12,701 results match your criteria Bronchiectasis


A review of non-cystic fibrosis bronchiectasis in children with a focus on the role of long-term treatment with macrolides.

Pediatr Pulmonol 2019 Jan 16. Epub 2019 Jan 16.

Unité de Pneumologie Pédiatrique, CHU Timone Enfants, Marseille, France.

Bronchiectasis is a rare chronic airway disease arising from several respiratory and systemic diseases. The grade of evidence for specific treatment of childhood bronchiectasis unrelated to cystic fibrosis (CF) is low with very few randomized controlled trials. Treatment has been based mainly on evidence from studies in adults with non-cystic fibrosis bronchiectasis and patients with cystic fibrosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ppul.24252DOI Listing
January 2019

Cardiorespiratory Responses to Glittre ADL Test in Bronchiectasis: A Cross-Sectional Study.

Can Respir J 2018 17;2018:7470387. Epub 2018 Dec 17.

Associate Professor, Department of Pulmonary Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Mangaluru 575004, India.

Background: Bronchiectasis is a chronic respiratory condition characterised by chronic sputum production, fatigue, and dyspnoea. These symptoms will lead to reduced exercise capacity and a reduced ability to carry out activities of daily living. Glittre ADL test is a valid and reliable test which evaluates the activities of daily living. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2018/7470387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311838PMC
December 2018

Respiratory medicine: bronchiectasis.

Authors:
John Firth

Clin Med (Lond) 2019 Jan;19(1):64-67

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7861/clinmedicine.19-1-64DOI Listing
January 2019

Airway clearance, mucoactive therapies and pulmonary rehabilitation in bronchiectasis.

Respirology 2019 Jan 16. Epub 2019 Jan 16.

The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, UK.

This paper aims to provide physiological rationale for airway clearance, mucoactive therapy and pulmonary rehabilitation (PR) (or exercise interventions) in bronchiectasis. There is increasing emphasis on the role of airway clearance techniques (ACT) in the management of bronchiectasis. No single ACT has currently shown superior effect over another. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/resp.13459DOI Listing
January 2019
1 Read

Pulmonary Cavitary Disease Secondary to Mycobacterium xenopi Complicated by Respiratory Failure.

Cureus 2018 Oct 29;10(10):e3512. Epub 2018 Oct 29.

Internal Medicine, Staten Island University Hospital, Northwell Health, Staten Island, USA.

Non-tuberculous mycobacteria (NTM) are a significant cause of pulmonary infection worldwide and can be clinically challenging. Mycobacterium xenopi (M. xenopi) has low pathogenicity and usually requires either host immune impairment, as in the case of a human immunodeficiency virus infection, or a structural lung disease to cause a clinical disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.3512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318116PMC
October 2018

Chronic cough in a patient with stable ulcerative colitis: a rare but important extraintestinal manifestation of inflammatory bowel disease.

BMJ Case Rep 2019 Jan 14;12(1). Epub 2019 Jan 14.

Respiratory Division of Medicine, University College London, London, UK.

A 74-year-old woman presented to her general practitioner with cough and occasional sputum production. Having failed to respond to courses of antibiotics in the community, she was referred to the thoracic medicine clinic. High-resolution CT chest revealed cylindrical bronchiectasis predominantly in the right lower lobe. Read More

View Article

Download full-text PDF

Source
http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22706
Publisher Site
http://dx.doi.org/10.1136/bcr-2018-227066DOI Listing
January 2019
1 Read

Noncystic fibrosis bronchiectasis management: opportunities and challenges.

Curr Opin Pulm Med 2019 Jan 10. Epub 2019 Jan 10.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

Purpose Of Review: Noncystic fibrosis bronchiectasis is a challenging disease which carries a heavy healthcare burden and significant mortality and morbidity. This review highlights the challenges in the diagnosis of bronchiectasis and discusses the management strategies and research opportunities in this field.

Recent Findings: The challenges in the management of bronchiectasis appear to be multifactorial, arising from both etiological heterogeneity and disease-specific management. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MCP.0000000000000562DOI Listing
January 2019

Allergic bronchopulmonary aspergillosis screening in bronchiectasis: is there always a precise answer to a clear question?

Eur Ann Allergy Clin Immunol 2019 Jan;51(1):41-43

Cardio-Thoracic-Vascular Department, University of Milano Bicocca, Respiratory Unit, San Gerardo Hospital, ASST Monza, Monza, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.23822/EurAnnACI.1764-1489.62DOI Listing
January 2019

Low transmission risk of in a bronchiectasis clinic based on the knowledge of bacterial population biology.

Eur Respir J 2019 Jan 11. Epub 2019 Jan 11.

Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), German Center for Lung Research, Hannover, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/13993003.02191-2018DOI Listing
January 2019

A young woman with upper lobe predominant bronchiectasis.

BMJ 2019 Jan 10;364:k5244. Epub 2019 Jan 10.

Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida College of Medicine, Gainesville, FL, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.k5244DOI Listing
January 2019

Acute Exacerbation of Idiopathic Interstitial Pneumonia in a Patient with Hepatocellular Carcinoma after Transcatheter Arterial Therapy Using Miriplatin.

Intern Med 2019 Jan 10. Epub 2019 Jan 10.

Department of Respiratory Medicine, Kumamoto University Hospital, Japan.

A 76-year-old Japanese woman with recurrent hepatocellular carcinoma presented with acute exacerbation of idiopathic interstitial pneumonia (AE-IIP) after transcatheter arterial therapy using miriplatin. She had a history of preexisting IIP five years before presenting at our hospital. On day 4 after transcatheter arterial therapy, she complained of shortness of breath. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2169/internalmedicine.1446-18DOI Listing
January 2019

Predictive factors for relapse of cryptogenic organizing pneumonia.

BMC Pulm Med 2019 Jan 9;19(1):10. Epub 2019 Jan 9.

Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.

Background: Relapse of cryptogenic organizing pneumonia (COP) may lead to poor long-term prognosis and necessitates multiple rounds of steroid treatment with potential adverse effects. The objective of this study is to identify predictive factors of COP relapse by comparing demographic and clinical variables between relapse and non-relapse groups.

Methods: During 2008-2013, 33 COP patients were treated, of which 23 (69. Read More

View Article

Download full-text PDF

Source
https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890
Publisher Site
http://dx.doi.org/10.1186/s12890-018-0764-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327473PMC
January 2019
2 Reads

Objectively measured physical activity and sedentary behaviour in children with bronchiectasis: a cross-sectional study.

BMC Pulm Med 2019 Jan 8;19(1). Epub 2019 Jan 8.

Institute of Health and Biomedical Innovation, Centre for Children's Health Research, Queensland University of Technology, Brisbane, Australia.

Background: Bronchiectasis is a major contributor to respiratory morbidity and health care utilization in children and youth. Current treatment guidelines for bronchiectasis recommend participation in regular physical activity (PA) to improve aerobic fitness and quality of life (QoL). However, no previous study has assessed physical activity and sedentary behavior in this patient group, and the extent to which children with bronchiectasis meet guidelines for PA is unknown. Read More

View Article

Download full-text PDF

Source
https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890
Publisher Site
http://dx.doi.org/10.1186/s12890-018-0772-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323769PMC
January 2019
3 Reads

Technical considerations for lung transplantation in Kartagener's syndrome.

Ann Thorac Surg 2018 Oct 26. Epub 2018 Oct 26.

Division of Cardiothoracic Surgery, Department of Surgery. Electronic address:

Kartagener's syndrome is a rare genetic disorder of ciliated epithelial cells associated with recurrent respiratory tract infections, bronchiectasis, and situs inversus. In some patients the accumulation of airway secretions and recurrent infections lead to end-stage lung disease, for which lung transplantation (LT) is the only effective treatment. Anatomical variations, such as dextrocardia and pulmonary situs inversus, make the procedure challenging, yet feasible with certain technical modifications and careful preparation of donor lungs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.athoracsur.2018.08.095DOI Listing
October 2018
3 Reads

Number and cost of hospitalizations with principal and secondary diagnoses of tuberculosis, United States.

Int J Tuberc Lung Dis 2018 Dec;22(12):1495-1504

National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Objective: To estimate the number and cost of hospitalizations with a diagnosis of active tuberculosis (TB) disease in the United States.

Methods: We analyzed the 2014 National In-Patient Sample using the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9) codes to identify hospitalizations with a principal (TB-PD) or any secondary discharge (TB-SD) TB diagnosis. We used a generalized linear model with log link and gamma distribution to estimate the cost per TB-PD and TB-SD episode adjusted for patient demographics, insurer, clinical elements, and hospital characteristics. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5588/ijtld.18.0260DOI Listing
December 2018
1 Read

Pulmonary Bronchiectasis Mimicking a Giant Hydatid Cyst.

Ann Thorac Surg 2018 Dec 31. Epub 2018 Dec 31.

Department of Thoracic Surgery, Manchester University Foundation Trust, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.athoracsur.2018.11.063DOI Listing
December 2018

Clinical analysis of pneumonectomy for destroyed lung: a retrospective study of 32 patients.

Gen Thorac Cardiovasc Surg 2019 Jan 2. Epub 2019 Jan 2.

Departmant of Thoracic Surgery, Yuzuncu Yil University, Van, Turkey.

Objective: Destroyed lung is whole lung destruction secondary to chronic or recurrent lung infections. This clinical condition can result in irreversible changes in the lung parenchyma. In this study, we aimed to evaluate patients undergoing pneumonectomy with a diagnosis of lung destruction in terms of surgical technique, post-operative morbidity and mortality, and long-term outcomes. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11748-018-01055-6
Publisher Site
http://dx.doi.org/10.1007/s11748-018-01055-6DOI Listing
January 2019
2 Reads

Development of bronchiectasis during long-term rituximab treatment for rheumatoid arthritis.

Adv Respir Med 2018 Dec 30. Epub 2018 Dec 30.

GIRAT, Fundación Valle del Lili - Universidad Icesi, Cra. 98 18-49, 760026 Cali, Colombia.

Here the cases of three female patients who received long-term rituximab treatment for seropositive, erosive and deforming rheumatoid arthritis was reported. After rituximab treatment, they presented with recurrent sinusitis and pneumonia, followed by the subsequent development of bronchiectasis. A temporal relationship between rituximab treatment and the onset of respiratory complications was exposed as a possible pathogenic mechanism. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5603/ARM.a2018.0050DOI Listing
December 2018
3 Reads

Factors predisposing to non-tuberculous mycobacterial lung disease in the patients with respiratory isolates of non-tuberculous mycobacteria.

Adv Respir Med 2018 Dec 30. Epub 2018 Dec 30.

1st Department of Lung Diseases, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland.

Introduction: An increasing incidence rate of respiratory isolates of non-tuberculous mycobacteria (NTM) has been noted recently in most European countries as well as in the US. Despite many publications, there is no consensus concerning the importance of different factors in promoting NTM lung disease (NTMLD). The aim of the present retrospective study was to analyse patients with positive NTM respiratory isolates in search of factors predisposing to NTMLD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5603/ARM.a2018.0043DOI Listing
December 2018

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: Case series and a review of the literature.

Medicine (Baltimore) 2018 Dec;97(52):e13806

Department of Pathology.

Rationale: Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare idiopathic disease with only about 100 cases reported in the literature.

Patient Concerns: Here, we presented 4 cases of DIPNECH. Four patients included 2 females and 2 males, aged 54 to 64 years old; 3 had no smoking history and 1 had history of smoking for 30 years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000013806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314763PMC
December 2018
1 Read

[Can Perioperative Oscillating Positive Expiratory Pressure Practice Enhance Recovery 
in Lung Cancer Patients Undergoing Thorascopic Lobectomy?]

Zhongguo Fei Ai Za Zhi 2018 Dec;21(12):890-895

Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.

Background: Oscillatory positive expiratory pressure (OPEP) training is a kind of breathing exercise with Acapella. The clinical value of OPEP has been widely discussed in chronic obstructive pulmonary disease, bronchiectasis as well as pulmonary cyst. However, few studies have explored the application of OPEP in surgery lung cancer patients underwent lobectomy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3779/j.issn.1009-3419.2018.12.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318571PMC
December 2018
8 Reads

Therapeutic drug monitoring and adverse events of delayed-release posaconazole tablets in patients with chronic pulmonary aspergillosis.

J Antimicrob Chemother 2018 Dec 26. Epub 2018 Dec 26.

Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

Background: Posaconazole delayed-release tablets offer better bioavailability than the liquid suspension, but no post-marketing data are available in immunocompetent hosts such as those with chronic pulmonary aspergillosis (CPA).

Objectives: To explore the pharmacokinetics and adverse event (AE) profile of posaconazole tablets in patients with CPA.

Methods: Patients started on posaconazole tablets at the National Aspergillosis Centre (NAC), Manchester, UK between February 2014 and October 2015 were identified from the NAC database and analysed retrospectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jac/dky539DOI Listing
December 2018
1 Read

Case 40-2018: A 47-Year-Old Woman with Recurrent Sinusitis, Cough, and Bronchiectasis.

N Engl J Med 2018 Dec;379(26):2558-2565

From the Departments of Medicine (J.E.M., C.J.R.), Radiology (J.S.H.), and Pathology (L.P.H.), Massachusetts General Hospital, and the Departments of Medicine (J.E.M., C.J.R.), Radiology (J.S.H.), and Pathology (L.P.H.), Harvard Medical School - both in Boston.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMcpc1810388DOI Listing
December 2018

Recommended Reading from the Johns Hopkins University Pulmonary and Critical Care Fellows.

Am J Respir Crit Care Med 2018 Dec 26. Epub 2018 Dec 26.

Johns Hopkins University School of Medicine, Pulmonary and Critical Care Medicine, Baltimore, Maryland, United States ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201805-0848RRDOI Listing
December 2018
1 Read

An approach to the child with a wet cough.

Authors:
F J Gilchrist

Paediatr Respir Rev 2018 Nov 23. Epub 2018 Nov 23.

Institute of Applied Clinical Science, Keele University, Keele ST5 5BG, UK; Academic Department of Child Health, Royal Stoke University Hospital, University Hospitals of North Midlands NHS Trust, Stoke on Trent ST4 6QG, UK. Electronic address:

When children have a wet cough, it suggests the presence of secretions in their airways. This often has an infectious aetiology which is usually a self-limiting viral infection requiring no investigation or treatment. In those with acute wet cough it is, however, important to identify features suggestive of community acquired pneumonia or an inhaled foreign body as these causes require specific management. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prrv.2018.11.002DOI Listing
November 2018
1 Read

Thoracic manifestations of adult T-cell leukemia/lymphoma on chest CT: difference between clinical subtypes.

Diagn Interv Radiol 2019 Jan;25(1):55-61

Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, Nishihara, Okinawa, Japan.

Purpose: We aimed to evaluate thoracic computed tomography (CT) findings in adult T-cell leukemia/lymphoma (ATL) and their differences among clinical subtypes.

Methods: Thoracic CT scans of 49 ATL patients were retrospectively reviewed. On CT scans, the presence of lung parenchymal abnormalities (10 patterns), enlarged lymph nodes, pleural and pericardial effusions, and subcutaneous nodules was evaluated by two radiologists in cooperation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5152/dir.2018.18038DOI Listing
January 2019

Review shows paediatric protracted bacterial bronchitis needs an accurate diagnosis and strictly targeted extended antibiotics.

Authors:
Matti Korppi

Acta Paediatr 2018 Dec 23. Epub 2018 Dec 23.

Center for Child Health Research, Tampere University and University Hospital, Tampere, Finland.

Aim: In 2017, the European Respiratory Society task force stated that protracted bacterial bronchitis (PBB) was a distinct clinical entity and outlined the diagnostic criteria and principles for treatment. However, this guidance was based on data from Australia and the USA. This mini review evaluated the data and addressed the lack of research-based data from Europe. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/apa.14705
Publisher Site
http://dx.doi.org/10.1111/apa.14705DOI Listing
December 2018
5 Reads

Pulmonary rehabilitation in bronchiectasis: a propensity matched study.

Eur Respir J 2018 Dec 21. Epub 2018 Dec 21.

Harefield Pulmonary Rehabilitation and Muscle Research Group, Royal Brompton & Harefield NHS Foundation Trust, UK.

International guidelines recommend pulmonary rehabilitation (PR) for patients with bronchiectasis, supported by small trials and data extrapolated from chronic obstructive pulmonary disease (COPD). However, it is unknown whether real-life data on completion rates and response to PR are similar between patients with bronchiectasis and COPD. Using propensity score matching, 213 consecutive patients with bronchiectasis referred for a supervised PR programme were matched 1:1 with a control group of 213 patients with COPD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/13993003.01264-2018DOI Listing
December 2018
1 Read

Kartagener syndrome complicated by immunoglobulin A nephropathy.

Int Med Case Rep J 2018 10;11:359-362. Epub 2018 Dec 10.

Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan,

We herein report the case of a 36-year-old woman with Kartagener syndrome (KS), which is an autosomal recessive disorder defined by a triad of bronchiectasis, sinusitis, and situs inversus, with complications of asymptomatic microhematuria and proteinuria. She was finally diagnosed with biopsy-proven immunoglobulin (Ig) A nephropathy. KS constitutes a subgroup of primary ciliary dyskinesia (PCD) characterized by structural and/or functional ciliary abnormalities resulting in sinopulmonary involvement with varying severity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/IMCRJ.S185887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292226PMC
December 2018
1 Read

The characteristics and clinical significance of mucin levels in bronchoalveolar lavage fluid of patients with interstitial lung disease.

J Investig Med 2018 Dec 19. Epub 2018 Dec 19.

Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China.

To investigate the expression and clinical significance of secretory mucins in patients with interstitial lung disease (ILD). The bronchoalveolar lavage fluid (BALF) concentrations of mucins (MUCs) from 27 patients with ILD, 6 patients with lung cancer, 8 patients with pleural effusion and 9 patients with bronchiectasis were determined by ELISA. The concentration of MUC5AC was significantly increased in patients with ILD (12. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jim-2018-000785DOI Listing
December 2018
1 Read
1.503 Impact Factor

High-resolution computed tomography findings in humoral primary immunodeficiencies and correlation with pulmonary function tests.

World J Radiol 2018 Nov;10(11):172-183

Institute of Radiology, Department of Medicine, University of Udine, Azienda Sanitaria Universitaria Integrata di Udine, Udine 33100, Italy.

Aim: To compare high-resolution computed tomography (HRCT) findings between humoral primary immunodeficiencies (hPIDs) subtypes; to correlate these findings to pulmonary function tests (PFTs).

Methods: We retrospectively identified 52 consecutive adult patients with hPIDs who underwent 64-row HRCT and PFTs at the time of diagnosis. On a per-patient basis, an experienced radiologist recorded airway abnormalities (bronchiectasis, airway wall thickening, mucus plugging, tree-in-bud, and air-trapping) and parenchymal-interstitial abnormalities (consolidations, ground-glass opacities, linear and/or irregular opacities, nodules, and bullae/cysts) found on HRCT. Read More

View Article

Download full-text PDF

Source
http://www.wjgnet.com/1949-8470/full/v10/i11/172.htm
Publisher Site
http://dx.doi.org/10.4329/wjr.v10.i11.172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288673PMC
November 2018
7 Reads

Spotlight on inhaled ciprofloxacin and its potential in the treatment of non-cystic fibrosis bronchiectasis.

Drug Des Devel Ther 2018 27;12:4059-4066. Epub 2018 Nov 27.

Alfa Institute of Biomedical Sciences (AIBS), Athens, Greece,

Non-cystic fibrosis bronchiectasis (NCFB) is a severe chronic illness characterized by irreversible dilation of airways and thickening of bronchial walls, chronic inflammation, repeated infections, and progressive obstruction of the airways. In contrast to cystic fibrosis bronchiectasis (CFB), which is a well-defined genetic disorder, NCFB is a heterogeneous disease caused by many different medical entities. Inhaled antibiotics are effective for patients with CFB, but their efficacy in NCFB has not been proven. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/DDDT.S168014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267620PMC
November 2018

in idiopathic cystic bronchiectasis.

BMJ Case Rep 2018 Nov 28;11(1). Epub 2018 Nov 28.

Kettering Hospital, Kettering, UK.

This is the first case in the English language describing in a patient with idiopathic bronchiectasis. A 66-year-old man with bronchiectasis presented with shortness of breath to the emergency department of our institution, a district hospital in the UK. His medications included long-term supplemental oxygen therapy and prophylactic azithromycin. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2015-211610DOI Listing
November 2018
1 Read

Eosinophilic lung disease with plastic bronchitis and bronchiectasis in an adolescent male.

Clin Case Rep 2018 Dec 26;6(12):2407-2410. Epub 2018 Oct 26.

University of Illinois College of Medicine at Peoria Peoria Illinois.

Any case of unresolving chronic pneumonia with expectoration of thick mucoid plugs should have high index of suspicion for plastic/cast bronchitis, requiring early flexible bronchoscopy with lavage and histopathologic evaluation. Associated presence of idiopathic chronic eosinophilic pneumonia is unusual and could be considered as a cause for atypical plastic bronchitis complicated by bronchiectasis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ccr3.1853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293265PMC
December 2018
2 Reads

Automated computed tomographic scoring of lung disease in adults with primary ciliary dyskinesia.

BMC Pulm Med 2018 Dec 18;18(1):194. Epub 2018 Dec 18.

Radiology Department, Groupe Hospitalier Cochin-Hôtel Dieu, AP-HP, Université Paris Descartes - Sorbonne Paris Cité, Paris, France.

Background: The present study aimed to develop an automated computed tomography (CT) score based on the CT quantification of high-attenuating lung structures, in order to provide a quantitative assessment of lung structural abnormalities in patients with Primary Ciliary Dyskinesia (PCD).

Methods: Adult (≥18 years) PCD patients who underwent both chest CT and spirometry within a 6-month period were retrospectively included. Commercially available lung segmentation software was used to isolate the lungs from the mediastinum and chest wall and obtain histograms of lung density. Read More

View Article

Download full-text PDF

Source
https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890
Publisher Site
http://dx.doi.org/10.1186/s12890-018-0758-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299576PMC
December 2018
4 Reads
2.489 Impact Factor

Pulmonary arteriovenous malformations leading to hypoxemia in child with primary ciliary dyskinesia.

Pediatr Pulmonol 2018 Dec 18. Epub 2018 Dec 18.

Congenital Heart Center, Spectrum Health Helen DeVos Children's Hospital, Grand Rapids, Michigan.

Primary ciliary dyskinesia (PCD) is a rare genetic condition characterized by respiratory tract infections, situs inversus or heterotaxy, and male infertility. Chronic respiratory infections begin in childhood and result in complications such as bronchiectasis. As hypoxemia is often attributed to bronchiectasis, other etiologies for desaturation in this setting are not routinely evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ppul.24198DOI Listing
December 2018

Host Variability in NTM Disease: Implications for Research Needs.

Front Microbiol 2018 3;9:2901. Epub 2018 Dec 3.

Laboratory of Chronic Airway Infection, Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States.

Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that may cause opportunistic infections in susceptible hosts. Lung infections in immunocompetent persons with structural lung disease are most common, while disseminated disease occurs primarily in immunocompromised individuals. Human disease caused by certain species, such as complex, , and , is increasing in incidence and varies by geographic distribution. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2018.02901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286975PMC
December 2018

Differentiation of Common Variable Immunodeficiency from Igg Deficiency.

J Allergy Clin Immunol Pract 2018 Dec 14. Epub 2018 Dec 14.

Division of Clinical Immunology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York. Electronic address:

Background: Common variable immunodeficiency (CVID) and IgG deficiency are two of the more prevalent primary humoral immune defects. Whereas the former is defined by consensus with criteria for quantitative and qualitative antibody defects, the latter is used to describe patients with reduced IgG, who commonly have recurrent sinopulmonary infections but do not fulfill CVID criteria. However, these patients are often given this diagnosis. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22132198183082
Publisher Site
http://dx.doi.org/10.1016/j.jaip.2018.12.004DOI Listing
December 2018
6 Reads

Radiologic types of Mycobacterium xenopi pulmonary disease: different patients with similar short-term outcomes.

Eur J Clin Microbiol Infect Dis 2018 Dec 14. Epub 2018 Dec 14.

Division of Respirology, Department of Medicine, University of Toronto, Toronto, ON, Canada.

Mycobacterium xenopi pulmonary disease (Mxe-PD) is common among nontuberculous mycobacterial infections in Europe and Canada. Associations between radiological pattern and clinical features and outcomes are inadequately studied in Mxe-PD. We sought to investigate clinical characteristics and outcomes according to the dominant radiological pattern among patients with Mxe-PD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10096-018-3437-xDOI Listing
December 2018

A retrospective study of factors associated with treatment decision for nontuberculous mycobacterial lung disease in adults without altered systemic immunity.

BMC Infect Dis 2018 Dec 14;18(1):659. Epub 2018 Dec 14.

Département des Maladies infectieuses et tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 103, Grande-Rue de la Croix-Rousse, 69317, cedex 04, Lyon, France.

Background: Nontuberculous mycobacteria (NTM) lung diseases are increasingly recognized as chronic opportunistic infections, occurring in individuals with a wide variety of underlying conditions. In the absence of systemic immunodeficiency, decision of NTM lung disease treatment must relies on a careful risk/benefit assessment, given the requirement of long-term administration of multidrug therapies supported by limited evidence. The primary objective was to identify the factors associated with anti-NTM treatment initiation. Read More

View Article

Download full-text PDF

Source
https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
Publisher Site
http://dx.doi.org/10.1186/s12879-018-3559-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295085PMC
December 2018
1 Read

Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group.

J Clin Immunol 2018 Dec 13. Epub 2018 Dec 13.

Paediatric Immunology Unit, Department of Paediatric Pulmonology, Allergology and Neonatology, Hanover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.

Studies of chest computed tomography (CT) in patients with primary antibody deficiency syndromes (ADS) suggest a broad range of bronchial pathology. However, there are as yet no multicentre studies to assess the variety of bronchial pathology in this patient group. One of the underlying reasons is the lack of a consensus methodology, a prerequisite to jointly document chest CT findings. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10875-018-0577-9
Publisher Site
http://dx.doi.org/10.1007/s10875-018-0577-9DOI Listing
December 2018
4 Reads

Updated BTS Adult Bronchiectasis Guideline 2018: a multidisciplinary approach to comprehensive care.

Thorax 2019 Jan;74(1):1-3

Host Defence Unit, Division of Respiratory Medicine, Royal Brompton Hospital, London, UK.

The new British Thoracic Society (BTS) Guideline for Bronchiectasis in Adults has been published. This article provides a summary of key highlights of the new BTS Guideline and covers who to investigate, what investigations should be carried out and a management strategy. Read More

View Article

Download full-text PDF

Source
http://thorax.bmj.com/lookup/doi/10.1136/thoraxjnl-2018-2124
Publisher Site
http://dx.doi.org/10.1136/thoraxjnl-2018-212468DOI Listing
January 2019
13 Reads

Economic burden of bronchiectasis in Germany.

Eur Respir J 2018 Dec 5. Epub 2018 Dec 5.

Department of Respiratory Medicine, Hannover Medical School and Biomedical Research in End-stage and Obstructive Lung disease (BREATH), German Center for Lung Research (DZL), Hannover, Germany.

Estimates of healthcare costs for incident bronchiectasis patients are currently not available for any European country. Out of a sample of 4 859 013 persons covered by German statutory health insurance companies, 231 new bronchiectasis patients were identified in 2012. They were matched with 685 control patients by age, gender and Charlson Comorbidity Index and followed for 3 years. Read More

View Article

Download full-text PDF

Source
http://erj.ersjournals.com/lookup/doi/10.1183/13993003.02033
Publisher Site
http://dx.doi.org/10.1183/13993003.02033-2018DOI Listing
December 2018
10 Reads

Prevalence of allergic bronchopulmonary aspergillosis in asthmatic patients: A prospective institutional study.

Indian J Tuberc 2018 Oct 13;65(4):285-289. Epub 2018 Apr 13.

Director, National Institute of Tuberculosis and Respiratory Diseases, Sri Aurobindo Marg, New Delhi 110030, India.

Background: Allergic bronchopulmonary aspergillosis (ABPA) is characterized by an allergic inflammatory response to colonization by Aspergillus species, most commonly Aspergillus fumigatus.

Aim: To study the prevalence of ABPA in asthmatic patients presenting to our institute.

Materials And Methods: All consecutive asthma patients attending our allergy clinic Out Patient Department (OPD) over a period of 20 months were tested with skin prick test (SPT) for Aspergillus antigens and those who were found positive were further evaluated for ABPA using Greenberger's criteria. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijtb.2018.04.007DOI Listing
October 2018
2 Reads

Health Perception and Behaviors in Adults With Bronchiectasis.

Respir Care 2018 Dec 11. Epub 2018 Dec 11.

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, China.

Background: Bronchiectasis is a chronic debilitating suppurative disease that significantly impacts quality of life. Clinical outcomes like exacerbations, are usually physician centered; however, the patients' experience, health-related behaviors, and expectations have frequently been neglected. In addition, patients' health perceptions may be influenced by their culture. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4187/respcare.06394DOI Listing
December 2018
2 Reads

Allergic bronchopulmonary aspergillosis successfully treated with mepolizumab: Case report and review of the literature.

Respir Med Case Rep 2019 24;26:59-62. Epub 2018 Nov 24.

Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan.

A 56-year-old woman was referred to our hospital for recurrent asthma of 20 years duration. She was diagnosed as having allergic bronchopulmonary aspergillosis on the basis of clinical symptoms, peripheral blood eosinophilia, elevated total serum immunoglobulin E value, positive results of specific IgE and precipitating antibodies against sp., central bronchiectasis, and mucoid impaction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rmcr.2018.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263094PMC
November 2018
7 Reads

The association between computed tomography scan findings of pulmonary infection caused by atypical mycobacteria and bacillus count in sputum samples.

Int J Mycobacteriol 2018 Oct-Dec;7(4):355-357

Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: The use of imaging techniques is important for prompt diagnosis and treatment of atypical mycobacterial infections; it also reduces the burden of these infections. The purpose of the present study was to determine the association between computed tomography (CT) scan findings of pulmonary infection caused by atypical mycobacteria and bacillus count in sputum samples.

Methods: This cross-sectional, observational, comparative study included 50 consecutive patients with pulmonary infection caused by atypical mycobacteria, who were hospitalized in Masih-Daneshvari Hospital of Tehran, Iran during 2012-2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/ijmy.ijmy_139_18DOI Listing
December 2018
1 Read