233 results match your criteria Broad Ligament Disorders


Novel p.G1344E mutation in is associated with ectopia lentis.

Br J Ophthalmol 2020 May 13. Epub 2020 May 13.

Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Background: Ectopia lentis refers to dislocation or subluxation of the crystalline lens. Fibrillin-1, encoded by , is an important microfibrillar structural component that is specifically required for the suspensory ligament of the lens. mutations may cause abnormal structure of microfibrils and has been associated with a broad spectrum of clinical phenotypes. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2019-315265DOI Listing

Novel molecular cues for dental defects in hypophosphatasia.

Exp Cell Res 2020 Apr 22:112026. Epub 2020 Apr 22.

Bernhard-Heine-Center for Locomotion Research, University of Würzburg, Würzburg, Germany. Electronic address:

Mineralization disorders with a broad range of etiological factors represent a huge challenge in dental diagnosis and therapy. Hypophosphatasia (HPP) belongs to the rare diseases affecting predominantly mineralized tissues, bones and teeth, and occurs due to mutations in the ALPL gene, which encodes tissue-nonspecific alkaline phosphatase (TNAP). Here we analyzed stem cells from bone marrow (BMSCs), dental pulp (DPSCs) and periodontal ligament (PDLSCs) in the absence and presence of efficient TNAP inhibitors. Read More

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http://dx.doi.org/10.1016/j.yexcr.2020.112026DOI Listing

Symptoms in Dilating Venous Disease.

Curr Cardiol Rev 2020 Mar 11. Epub 2020 Mar 11.

Istinye University Faculty of Medicine Liv Hospital, Department of Cardiology. Turkey.

Lower extremity venous diseases or insufficiency include clinically deteriorating conditions with morphological and functional alterations of the venous system including venous hypertension, vascular wall structural abnormality, and venous valvar incompetency in association with a inflammatory process . In fact the same pathophysiological processes are the main underlying mechanisms of other venous insufficiencies in different vascular territories such as varicocele, pelvic varicosities or congestion syndrome and hemorrhoids.Regarding the anatomical continuity of lower extremity venous system, urogenital system (pampiniform plexus in male and broad ligament and ovarian veins in female) and anorectal venous system, it is reasonable to expect common symptoms such as pain, burning sensation, pruritis, swelling, which arises direclty from the involved tissue itself. Read More

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http://dx.doi.org/10.2174/1573403X16666200312101245DOI Listing

Female adnexal tumors of probable Wolffian origin: morphological, immunohistochemical, and molecular analysis of 15 cases.

Mod Pathol 2020 04 7;33(4):734-747. Epub 2019 Oct 7.

Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.

Female adnexal tumors of probable Wolffian origin are rare and present a diagnostic challenge due to their morphological and immunohistochemical overlap with more common ovarian and broad ligament entities. We evaluated the morphological, immunohistochemical, and molecular features of 15 tumors of probable Wolffian origin. Patients ranged from 32 to 69 (mean 47) years and tumors from 1. Read More

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http://dx.doi.org/10.1038/s41379-019-0375-9DOI Listing
April 2020
4 Reads

Volumetric Cone Beam Computed Tomography for the Assessment of Oral Manifestations in Systemic Sclerosis: Data from an EUSTAR Cohort.

J Clin Med 2019 Oct 4;8(10). Epub 2019 Oct 4.

Grigore T. Popa University of Medicine and Pharmacy, School of Medicine, Department of Rheumatology, Iasi 700115, Romania.

Background Oral health issues are commonly reported in systemic sclerosis (SSc), comprising a broad spectrum of manifestations, e.g., reduced mouth opening, periodontal disease, increased periodontal ligament (PDL) space width, and mandibular resorption. Read More

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http://dx.doi.org/10.3390/jcm8101620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832751PMC
October 2019
1 Read

Performance of PROMIS Computer Adaptive Testing As Compared With Established Instruments for Multiple-Ligament Knee Injuries.

Orthop J Sports Med 2019 Sep 5;7(9):2325967119867419. Epub 2019 Sep 5.

Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Background: The Patient-Reported Outcomes Measurement Information System (PROMIS) computer adaptive testing (CAT) is a patient-reported outcome metric that has been validated for anterior cruciate ligament (ACL) injuries, ACL reconstructions, and meniscal injuries. Thus far, the system has not been validated for multiligament knee injuries. The Multiligament Quality of Life (MLQOL) questionnaire is a validated, disease-specific patient-reported outcome instrument for this population that can serve as a gold standard for validation of the newer PROMIS. Read More

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http://dx.doi.org/10.1177/2325967119867419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728687PMC
September 2019
1 Read

En bloc resection of the external iliac vein along with broad ligament leiomyosarcoma: A case report.

Case Rep Womens Health 2019 Jul 27;23:e00131. Epub 2019 Jun 27.

Birmingham Cancer Research UK Cancer Centre, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham B15 2TT, UK.

Outcomes following the excision of the external iliac vein during gynaecological oncology surgery are poorly documented. This is because most gynaecological oncologists consider tumours with vascular involvement inoperable. We describe a patient whose right external iliac vein was transected during the removal of a large broad ligament leiomyosarcoma invading the right external iliac vein. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22149112193005
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http://dx.doi.org/10.1016/j.crwh.2019.e00131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639561PMC
July 2019
6 Reads

High-grade endometrial stromal sarcoma: a retrospective study of factors influencing prognosis.

Cancer Manag Res 2019 17;11:831-837. Epub 2019 Jan 17.

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China,

Objectives: The aim of this study was to evaluate the factors associated with progress-free survival (PFS) and overall survival (OS) in patients with high-grade endometrial stromal sarcoma (HG-ESS).

Patients And Methods: A total of 40 patients were enrolled in this study at the Peking Union Medical College Hospital, Beijing, China, from 2006 to 2016. The study retrospectively analyzed clinical and pathological data, and associations of these variables with PFS and OS were evaluated. Read More

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http://dx.doi.org/10.2147/CMAR.S187849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340498PMC
January 2019
15 Reads

Ulnar focal cortical indentation: a progressive, deforming variant of focal fibrocartilaginous dysplasia.

Pediatr Radiol 2019 02 15;49(2):187-195. Epub 2018 Nov 15.

Department of Musculoskeletal Radiology,, Temple University Hospital, 3401 N. Broad St., Philadelphia, PA, 19104, USA.

Background: Focal fibrocartilaginous dysplasia is a rare growth disturbance of bone resulting in deformity. In the ulna, focal fibrocartilaginous dysplasia is particularly rare, and the characteristic fibroligamentous tether can result in progressive deformity with progressive dislocation of the radial head. The fibroligamentous tether is similar in appearance and function to the Vickers ligament seen in Madelung deformity. Read More

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http://dx.doi.org/10.1007/s00247-018-4294-6DOI Listing
February 2019
58 Reads

Fibroblast growth factor-2 inhibits CD40-mediated periodontal inflammation.

J Cell Physiol 2019 05 28;234(5):7149-7160. Epub 2018 Oct 28.

Department of Periodontology, Osaka University Graduate School of Dentistry, Osaka, Japan.

Fibroblast growth factor-2 (FGF-2) stimulates periodontal regeneration by a broad spectrum of effects on periodontal ligament (PDL) cells, such as proliferation, migration, and production of extracellular matrix. A critical factor in the success of periodontal regeneration is the rapid resolution of inflammatory responses in the tissue. We explored an anti-inflammatory effect of FGF-2 during periodontal regeneration and healing. Read More

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http://doi.wiley.com/10.1002/jcp.27469
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http://dx.doi.org/10.1002/jcp.27469DOI Listing
May 2019
44 Reads

Pancreaticoduodenectomy for the Management of Pancreatic or Duodenal Metastases from Primary Sarcoma.

Anticancer Res 2018 Jul;38(7):4041-4046

Department of Academic Surgery, The Royal Marsden Hospital, London, U.K.

Background/aim: Sarcomas are rare and heterogeneous solid tumours of mesenchymal origin and frequently have an aggressive course. The mainstay of management for localized disease is surgical excision. Following excision there is approximately 30-50% risk of developing distant metastases. Read More

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http://dx.doi.org/10.21873/anticanres.12693DOI Listing
July 2018
25 Reads
1.872 Impact Factor

A robust method for RNA extraction and purification from a single adult mouse tendon.

PeerJ 2018 24;6:e4664. Epub 2018 Apr 24.

Center for Regenerative Medicine, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Background: Mechanistic understanding of tendon molecular and cellular biology is crucial toward furthering our abilities to design new therapies for tendon and ligament injuries and disease. Recent transcriptomic and epigenomic studies in the field have harnessed the power of mouse genetics to reveal new insights into tendon biology. However, many mouse studies pool tendon tissues or use amplification methods to perform RNA analysis, which can significantly increase the experimental costs and limit the ability to detect changes in expression of low copy transcripts. Read More

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http://dx.doi.org/10.7717/peerj.4664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922231PMC
April 2018
11 Reads

Tumors in von Hippel-Lindau Syndrome: From Head to Toe-Comprehensive State-of-the-Art Review.

Radiographics 2018 May-Jun;38(3):849-866. Epub 2018 Mar 30.

From the Departments of Radiology (D.G.) and Pathology (P.R.), University of Texas MD Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler St, Unit 1473, Houston, TX 77030-4009; Department of Radiology, Mayo Clinic Arizona, Phoenix/Scottsdale, Ariz (C.O.M.); Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (P.J.P., M.G.L.); Department of Radiology, Indiana University School of Medicine, Indianapolis, Ind (K.S.); and Section of Abdominal Imaging, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (S.B.).

Von Hippel-Lindau syndrome (VHL) is an autosomal-dominant hereditary tumor disease that arises owing to germline mutations in the VHL gene, located on the short arm of chromosome 3. Patients with VHL may develop multiple benign and malignant tumors involving various organ systems, including retinal hemangioblastomas (HBs), central nervous system (CNS) HBs, endolymphatic sac tumors, pancreatic neuroendocrine tumors, pancreatic cystadenomas, pancreatic cysts, clear cell renal cell carcinomas, renal cysts, pheochromocytomas, paragangliomas, and epididymal and broad ligament cystadenomas. The VHL/hypoxia-inducible factor pathway is believed to play a key role in the pathogenesis of VHL-related tumors. Read More

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http://dx.doi.org/10.1148/rg.2018170156DOI Listing
October 2018
15 Reads

Acute abdominal pain due to internal herniation of the sigmoid colon, fallopian tube and left ovary, a rare presentation of Allen Masters syndrome.

Acta Chir Belg 2019 Aug 12;119(4):248-250. Epub 2018 Feb 12.

a Department of Visceral Surgery , Centre Hospitalier Universitaire Ambroise Paré , Mons , Belgium.

In 1955, Allen and Masters describe a painful syndrome which associates traumatic delivery to laceration found on the posterior leaf of the broad ligament. Herniation through this defect is a rare entity, accounted for about 4-7% of all internal hernias. Normally, it involves the small bowel. Read More

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http://dx.doi.org/10.1080/00015458.2018.1438558DOI Listing
August 2019
11 Reads

Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.

Pathology 2018 Feb 17;50(2):238-256. Epub 2018 Jan 17.

University of California San Francisco, Pathology Department, San Francisco, CA, United States. Electronic address:

The most common hereditary gynaecological tumour syndromes are hereditary breast and ovarian cancer syndrome and Lynch syndrome. However, pathologists also may encounter gynaecological tumours in women with rare hereditary syndromes. Many of these tumours exhibit distinctive gross and microscopic features that are associated with a risk for an inherited gene mutation. Read More

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http://dx.doi.org/10.1016/j.pathol.2017.10.009DOI Listing
February 2018
27 Reads

Two Childhood Pheochromocytoma Cases due to von Hippel-Lindau Disease, One Associated with Pancreatic Neuroendocrine Tumor: A Very Rare Manifestation

J Clin Res Pediatr Endocrinol 2018 06 12;10(2):179-182. Epub 2017 Oct 12.

İstanbul University Cerrahpasa Faculty of Medicine, Department of Pediatric Endocrinology, İstanbul, Turkey

von Hippel-Lindau (VHL) disease is an autosomal dominantly inherited disorder, characterized by hemangioblastomas of the retina and central nervous system (CNS); renal cysts; clear cell carcinoma; pheochromocytoma (PCC); endolymphatic sac tumors; cystadenomas of the epididymis in males; broad ligament of uterus in females; pancreatic cysts; cystadenomas; and neuroendocrine tumors. We report two cases of VHL disease that presented with PCC as the first manifestation. Further clinical developments during follow-up, hemangioblastoma of CNS in one case and a pancreatic neuroendocrine tumor (PNET) in the second case led to the diagnosis of VHL disease. Read More

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http://dx.doi.org/10.4274/jcrpe.5078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985389PMC
June 2018
18 Reads

Transplantation of periodontal ligament cell sheets expressing human β‑defensin‑3 promotes anti‑inflammation in a canine model of periodontitis.

Mol Med Rep 2017 Nov 19;16(5):7459-7467. Epub 2017 Sep 19.

Department of Oral Mucosal Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, P.R. China.

Periodontitis is a chronic oral inflammatory disease caused by microorganisms. Human β‑defensin‑3 (HBD‑3) is an endogenous antimicrobial peptide that inhibits a broad spectrum of microorganisms. Cell sheet technology has been widely applied in tissue and organ reconstructions. Read More

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http://dx.doi.org/10.3892/mmr.2017.7514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865878PMC
November 2017
18 Reads

Spinal cord compression syndrome caused by intraspinal epidural fibrous cord: Three case reports.

Medicine (Baltimore) 2017 Aug;96(33):e7592

Department of Spinal Surgery, Luoyang Orthopaedic Hospital of Henan Province, Luoyang, Henan, China.

Rationale: The spinal cord compression caused by intraspinal epidural fibrous cord.

Patient Concerns: All patients in this study had spinal cord compression syndrome caused by an intraspinal epidural fibrous cord, manifested as abnormally increased epidural adipose tissue by imaging.

Diagnose: These abnormal fibrous connective tissue strips were not identical to the known pathological tissue such as "meningovertebral ligament. Read More

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http://dx.doi.org/10.1097/MD.0000000000007592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571680PMC
August 2017
16 Reads

Peroneal tendon disorders.

EFORT Open Rev 2017 Jun 22;2(6):281-292. Epub 2017 Jun 22.

Department of Foot & Ankle Surgery, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, HA7 4LP, UK.

Pathological abnormality of the peroneal tendons is an under-appreciated source of lateral hindfoot pain and dysfunction that can be difficult to distinguish from lateral ankle ligament injuries.Enclosed within the lateral compartment of the leg, the peroneal tendons are the primary evertors of the foot and function as lateral ankle stabilisers.Pathology of the tendons falls into three broad categories: tendinitis and tenosynovitis, tendon subluxation and dislocation, and tendon splits and tears. Read More

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http://online.boneandjoint.org.uk/doi/10.1302/2058-5241.2.16
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http://dx.doi.org/10.1302/2058-5241.2.160047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508858PMC
June 2017
22 Reads

Expression and antimicrobial character of cells transfected with human β‑defensin‑3 against periodontitis‑associated microbiota in vitro.

Mol Med Rep 2017 Sep 4;16(3):2455-2460. Epub 2017 Jul 4.

Department of Oral Mucosal Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, P.R. China.

Periodontitis is an oral chronic inflammatory disease induced by microorganisms that can destroy tooth‑supporting structures. Human β‑defensin‑3 (HBD‑3) is a type of endogenous antimicrobial peptide that inhibits a broad spectrum of microorganisms. The objectives of the present study were to transfect human periodontal ligament cells (HPDLCs) and human bone marrow stromal cells (HBMSCs) with lentivirus containing the HBD‑3 gene, determine the transfection efficiency, and investigate the antimicrobial activity of the experimental cells against periodontal pathogens. Read More

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http://dx.doi.org/10.3892/mmr.2017.6913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547979PMC
September 2017
24 Reads

Recurrent female adnexal tumor of probable Wolffian origin treated with debulking surgery, imatinib and paclitaxel/carboplatin combination chemotherapy: A case report.

Oncol Lett 2017 May 17;13(5):3403-3408. Epub 2017 Mar 17.

Department of Obstetrics and Gynecology, Graduate School of Medicine, University of The Ryukyus, Okinawa 903-0215, Japan.

In view of the small number of recurrent and metastatic cases of female adnexal tumors of probable Wolffian origin (FATWO), there is a distinct lack of evidence to support recommendations regarding treatment. In the present study, a 37-year-old female was diagnosed with a left adnexal tumor and underwent a left salpingo-oophorectomy (SO). The tumor was found to arise from the left tubal fimbria and extend to the posterior leaf of the broad ligament. Read More

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http://dx.doi.org/10.3892/ol.2017.5874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431746PMC
May 2017
55 Reads

Arthroscopic Findings in Anterior Shoulder Instability.

Open Orthop J 2017 28;11:119-132. Epub 2017 Feb 28.

Department of Orthopaedic Surgery and Musculoskeletal Trauma, Faculty of Medicine, School of Health Sciences, University of Thessalia, Larissa, Greece.

Background: In the last years, basic research and arthroscopic surgery, have improved our understanding of shoulder anatomy and pathology. It is a fact that arthroscopic treatment of shoulder instability has evolved considerably over the past decades. The aim of this paper is to present the variety of pathologies that should be identified and treated during shoulder arthroscopy when dealing with anterior shoulder instability cases. Read More

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http://dx.doi.org/10.2174/1874325001711010119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366393PMC
February 2017
9 Reads

Unusual case of pelvic hydatid cyst of broad ligament mimicking an ovarian tumour.

JMM Case Rep 2016 Aug 30;3(4):e005057. Epub 2016 Aug 30.

Microbiology Department, Mubarak Al Kabeer Hospital, Kuwait City, Kuwait; Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.

Introduction: The diagnosis of hydatid cyst in female genital tract is rare and difficult. A high degree of clinical suspicion is needed for pre-operative investigations to exclude hydatid cyst of female pelvis. The objective of this presentation is to highlight a pelvic hydatid cyst that presented as an ovarian tumour. Read More

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http://dx.doi.org/10.1099/jmmcr.0.005057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330247PMC
August 2016
13 Reads

Preventive Biomechanics: A Paradigm Shift With a Translational Approach to Injury Prevention.

Am J Sports Med 2017 Sep 15;45(11):2654-2664. Epub 2017 Feb 15.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Background: Preventive medicine techniques have alleviated billions of dollars' worth of the economic burden in the medical care system through the implementation of vaccinations and screenings before the onset of disease symptoms. Knowledge of biomechanical tendencies has progressed rapidly over the past 20 years such that clinicians can identify, in healthy athletes, the underlying mechanisms that lead to catastrophic injuries such as anterior cruciate ligament (ACL) ruptures. As such, preventive medicine concepts can be applied to noncontact musculoskeletal injuries to reduce the economic burden of sports medicine treatments and enhance the long-term health of athletes. Read More

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http://dx.doi.org/10.1177/0363546516686080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405413PMC
September 2017
18 Reads

Risk of iatrogenic injury to the infrapatellar branch of the saphenous nerve during hamstring tendon harvesting: A meta-analysis.

Muscle Nerve 2017 Nov 29;56(5):930-937. Epub 2017 Apr 29.

International Evidence-Based Anatomy Working Group, Krakow, Poland.

Introduction: Our goal was to conduct a comprehensive analysis of studies reporting data on the rate of injury to the infrapatellar branch of the saphenous nerve following hamstring tendon graft harvesting with respect to the type of incision over the pes anserinus.

Methods: A broad search through all major electronic databases was conducted to identify articles eligible for inclusion. All available data were extracted and pooled into the analysis. Read More

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http://doi.wiley.com/10.1002/mus.25587
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http://dx.doi.org/10.1002/mus.25587DOI Listing
November 2017
14 Reads

[Injuries of major tendons : Review of current diagnostic and surgical standards].

Chirurg 2017 Feb;88(2):175-186

Klinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, 24105, Kiel, Deutschland.

Chronic degenerative tendon injuries as well as injuries due to acute high-energy trauma and incisional injuries are a significant aspect in the emergency surgery department. As a result of anatomical characteristics and exposure certain tendons are particularly vulnerable to injury. These include the biceps brachialis, quadriceps femoris, patella, achilles and tibialis anterior tendons. Read More

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http://dx.doi.org/10.1007/s00104-016-0367-yDOI Listing
February 2017
6 Reads

A case report of a patient with high β-hCG levels after operation because of primary broad ligament pregnancy.

Clin Exp Obstet Gynecol 2017 ;44(1):138-142

Introduction: A broad ligament pregnancy is an extremely rare condition and diagnosis is frequently missed and finally made during laparotomy. This is a case of a young patient with high serum beta-human chorionic gonadotropin (β-hCG) levels after operation because of broad ligament pregnancy.

Case Report: A 31-year-old multipara complained of intermittent lower abdominal pain with vaginal bleeding for four months. Read More

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May 2018
8 Reads

Ten Principles for Safe Surgical Treatment of Ovarian Endometriosis.

J Minim Invasive Gynecol 2017 02 5;24(2):203-204. Epub 2016 Dec 5.

Department of Obstetrics and Gynecology, University of São Paulo Medical School, São Paulo, Brazil. Electronic address:

Study Objective: To show a step-by-step laparoscopic approach for excision of an ovarian endometrioma following surgical principles for safety and maximal preservation of ovarian function.

Design: Video. Medical management of ovarian endometriomas is not recommended. Read More

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http://dx.doi.org/10.1016/j.jmig.2016.11.009DOI Listing
February 2017
11 Reads

Endoscopic ultrasound of the hepatoduodenal ligament and liver hilum.

Endosc Ultrasound 2018 May-Jun;7(3):168-174

Mount Sinai Elmhurst Hospital Center, Elmhurst, New York, USA.

The porta hepatis and hepatoduodenal ligament (HDL) are important anatomical pathways of extension of disease to and from the liver. The imaging of this area is difficult. The role of endoscopic ultrasound (EUS) as an imaging modality for hepatoduodenal ligament has not been established so far. Read More

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http://dx.doi.org/10.4103/2303-9027.193584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032695PMC
November 2016
30 Reads

Bowel Obstruction and Peritoneal Dialysis: A Case Report of a Patient with Complications from a Broad Ligament Hernia.

Clin Med Insights Case Rep 2016 8;9:57-60. Epub 2016 Aug 8.

Division of Nephrology, Department of Internal Medicine.

Abdominal hernias are a common cause of bowel obstruction. The major types of abdominal hernias are external or abdominal wall hernias, which occur at areas of congenital or acquired weakness in the abdominal wall. An alternative entity is internal hernias, which are characterized by a protrusion of viscera through the peritoneum or mesentery. Read More

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http://dx.doi.org/10.4137/CCRep.S40059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978204PMC
August 2016
28 Reads

[ALLEN-MASTERS SYNDROME AS A CAUSE FOR CHRONIC PELVIC PAIN: DIAGNOSIS, TREATMENT AND LONG TERM FOLLOW-UP].

Harefuah 2016 Apr;155(4):215-8, 255

Chronic pelvic pain is one of the main causes for repeated ambulatory and hospital visits. The main findings on exploratory laparoscopy performed for these complaints are endometriosis and adhesions, while in more than 50% of cases, no cause for the pain is found. In 1955, Allen and Masters reported pain associated with traumatic labor. Read More

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April 2016
22 Reads

Von Hippel-Lindau Disease: Genetics and Role of Genetic Counseling in a Multiple Neoplasia Syndrome.

J Clin Oncol 2016 06 25;34(18):2172-81. Epub 2016 Apr 25.

Sarah M. Nielsen and Lindsay Rhodes, The University of Chicago, Chicago, IL; Ignacio Blanco, Hospital Universitari Germans Trias i Pujol, UAB - Universitat Autònoma de Barcelona, Barcelona, Spain; Wendy K. Chung, Columbia University, New York, NY; Charis Eng, Cleveland Clinic; Charis Eng, Case Western Reserve University School of Medicine, Cleveland, OH; Eamonn R. Maher, University of Cambridge and Cambridge NIHR Biomedical Research Centre, Cambridge, United Kingdom; Stéphane Richard, Réseau National pour Cancers Rares de l'Adulte PREDIR, INCa/AP-HP, Hôpital Bicêtre, Le Kremlin Bicêtre; Stéphane Richard, INSERM U1186, Gustave Roussy Cancer Campus, Villejuif, France; Rachel H. Giles, University Medical Center Utrecht, Regenerative Medicine Center Utrecht, Utrecht; and Rachel H. Giles, Dutch VHL Patient Organization, Gouda, the Netherlands.

Von Hippel-Lindau disease (VHL) is one of the most common inherited neoplasia syndromes and is characterized by highly vascular tumors of the eyes, brain, and spine, as well as benign and malignant tumors and/or cysts of the kidneys, adrenal medullae and sympathetic paraganglia, endolymphatic sac, epididymis, and broad ligament. Since the discovery of the VHL gene in 1993, more than 900 families with VHL have been identified and examined. Genetic testing for VHL is widely available and will detect a disease-causing mutation in rate 95% to 100% of individuals who have a clinical diagnosis of VHL, making it the standard of care for diagnosis of VHL. Read More

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http://dx.doi.org/10.1200/JCO.2015.65.6140DOI Listing
June 2016
18 Reads

NOX1/2 activation in human gingival fibroblasts by Fusobacterium nucleatum facilitates attachment of Porphyromonas gingivalis.

Arch Microbiol 2016 Aug 12;198(6):573-83. Epub 2016 Apr 12.

Department of Oral Biochemistry, Dental Science Research Institute, Medical Research Center for Biomineralization Disorders, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea.

Periodontal diseases are infectious polymicrobial inflammatory diseases that lead to destruction of the periodontal ligament, gingiva, and alveolar bone. Sequential colonization of a broad range of bacteria, including Fusobacterium nucleatum and Porphyromonas gingivalis, is an important phenomenon in this disease model. F. Read More

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http://dx.doi.org/10.1007/s00203-016-1223-7DOI Listing
August 2016
27 Reads

Successful treatment of advanced stage yolk sac tumour of extragonadal origin: a case report and review of literature.

Acta Med Litu 2016 ;23(2):110-116

Medical Faculty, Vilnius University, Vilnius, Lithuania.

Background: Yolk sac tumour diagnosis should be considered for young age patients admitted to the hospital with non-specific complaints of widespread disease. Correct diagnosis and carefully planned treatment is the key to a successful outcome.

Methods And Materials: We present a rare case of a widespread yolk sack tumour of a uterine broad ligament. Read More

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http://dx.doi.org/10.6001/actamedica.v23i2.3327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088743PMC
January 2016
26 Reads

[Urinary, infectious and digestive adverse events related to benign hysterectomy and the associated surgery on the Fallopian tube: Guidelines].

J Gynecol Obstet Biol Reprod (Paris) 2015 Dec 31;44(10):1183-205. Epub 2015 Oct 31.

Département de gynécologie-obstétrique, hôpital Mère-Enfant, CHU de Limoges, avenue Larrey, 87000 Limoges, France.

Objectives: To provide clinical practice guidelines from the French College of Obstetrics and Gynecology (CNGOF) based on the best evidence available, concerning the urinary, infectious and digestive adverse events related to benign hysterectomy and the associated surgery including opportunistic salpingectomy and adnexectomy.

Material And Method: Review of literature using following keywords: benign hysterectomy; urinary injury; bladder injury; ureteral injury; vesicovaginal fistula; infection; bowel injury; salpingectomy.

Results: Urinary catheter should be removed before 24h following uncomplicated hysterectomy (grade B). Read More

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http://dx.doi.org/10.1016/j.jgyn.2015.09.031DOI Listing
December 2015
18 Reads

Retrospective Clinical and Radiological Outcomes after Robotic Assisted Bicompartmental Knee Arthroplasty.

Adv Orthop 2015 3;2015:747309. Epub 2015 Sep 3.

Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.

Purpose. Bicompartmental knee arthroplasty (BiKA) is a favorable alternative to total knee arthroplasty for degenerative disease limited to two knee compartments. Recently developed robotic-assisted systems improved the clinical efficacy of unicompartmental knee arthroplasty by providing enhanced component positioning with dynamic ligament balancing. Read More

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http://dx.doi.org/10.1155/2015/747309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573219PMC
September 2015
19 Reads

New von Hippel-Lindau manifestations develop at the same or decreased rates in pregnancy.

Neurology 2015 Oct 25;85(17):1500-3. Epub 2015 Sep 25.

From the Departments of Cellular and Molecular Medicine (M.L.M.B., E.B.-J., M.L.B.) and Biostatistics (E.B.-J.), University of Copenhagen, Denmark.

Objective: In a national retrospective cohort study, we aimed to determine the effect of pregnancy on new von Hippel-Lindau (vHL) tumor development during pregnancy and at 1, 3, and 5 years after conception.

Methods: We included 52 VHL mutation carriers (26 men and 26 women) with 581 manifestations diagnosed throughout their lifetimes. We analyzed age-dependent manifestation rates using Poisson regression. Read More

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http://dx.doi.org/10.1212/WNL.0000000000002064DOI Listing
October 2015
7 Reads

From arterial hypertension complications to von Hippel-Lindau syndrome diagnosis.

Ital J Pediatr 2015 Aug 13;41:56. Epub 2015 Aug 13.

Department of Paediatric Endocrinology and Diabetology, Medical University in Lublin, Poland, ul. Prof. A. Gebali 6, 20-093, Lublin, Poland.

Von Hippel-Lindau syndrome is a rare, genetically based, autosomal dominant disorder. Its course is accompanied by the development of multiple neoplasms with the following tumours diagnosed most commonly in the central nervous system haemangioblastoma, clear cell renal cell carcinoma, phaeochromocytomas, pancreatic islet tumours, and endolymphatic sac tumours. Additionally, renal and pancreatic cystadenomas and epididymal cystadenomas have been diagnosed in males and cystadenomas of the broad ligament of the uterus have been diagnosed in females. Read More

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http://www.ijponline.net/content/pdf/s13052-015-0158-y.pdf
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http://www.ijponline.net/content/41/1/56
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http://dx.doi.org/10.1186/s13052-015-0158-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535675PMC
August 2015
11 Reads

Madelung deformity and Madelung-type deformities: a review of the clinical and radiological characteristics.

Pediatr Radiol 2015 Nov 2;45(12):1856-63. Epub 2015 Jul 2.

Shriners Hospitals for Children, Philadelphia, PA, USA.

Madelung deformity of the distal radius results from premature closure of the medial volar aspect of the distal radial physis, leading to increased volar tilt and increased inclination of the radial articular surface, triangulation of the carpus with proximal migration of the lunate and dorsal displacement of the distal ulna. The deformity is particularly common in Leri-Weill dyschondrosteosis, but it may also occur in isolation. True Madelung deformity can be differentiated from Madelung-type deformities by the presence of an anomalous radiolunate ligament (Vickers ligament). Read More

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http://dx.doi.org/10.1007/s00247-015-3390-0DOI Listing
November 2015
26 Reads

Hybrid Graft Anterior Cruciate Ligament Reconstruction: A Predictable Graft for Knee Stabilization.

Orthopedics 2015 Jun;38(6):e473-6

Trauma to the anterior cruciate ligament (ACL) is a season-ending injury and involves months of activity modification and rehabilitation. The annual incidence of ACL tears in the United States is approximately 200,000, which allows for a broad range of individualized treatment options. Various surgical techniques, including transtibial and independent tunnel drilling, allograft and autograft tissue, and various implants, have been described in the literature. Read More

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http://dx.doi.org/10.3928/01477447-20150603-54DOI Listing
June 2015
13 Reads
2 Citations
0.980 Impact Factor

Efficacy and Safety of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Anterior Cruciate Ligament Reconstruction of a Rabbit Model: New Strategy to Enhance Tendon Graft Healing.

Arthroscopy 2015 Aug 14;31(8):1530-9. Epub 2015 Apr 14.

Department of Orthopaedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

Purpose: To investigate whether non-autologous transplantation of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) could be integrated safely at the bone-tendon junction without immune rejection and could enhance bone-tendon healing effectively during anterior cruciate ligament (ACL) reconstruction in an animal model.

Methods: ACL reconstructions using hamstring tendons were performed in 30 adult rabbits. The bone tunnels were treated with hUCB-MSCs or were untreated. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07498063150013
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http://dx.doi.org/10.1016/j.arthro.2015.02.023DOI Listing
August 2015
85 Reads

Unlinked total elbow arthroplasty.

Instr Course Lect 2015 ;64:231-42

Medical Director, Roth McFarlane Hand and Upper Limb Centre, Department of Surgery, St. Joseph's Health Centre, Western University, London, Ontario, Canada.

For more than 60 years, total elbow arthroplasty (TEA) has been successfully used to treat a variety of elbow conditions. Although first designed to treat older patients with rheumatoid arthritis, the indications have expanded to include younger, higher-demand patients with a broad range of elbow pathology. Two groups of TEA currently exist. Read More

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August 2015
11 Reads

Intravenous leiomyomatosis revisited: an experience of 14 cases at a single medical center.

Int J Gynecol Pathol 2015 Mar;34(2):169-76

Department of Pathology, Yale School of Medicine, New Haven, Connecticut.

Intravenous leiomyomatosis (IVL) is a rare neoplasm of smooth muscle origin with the capacity for distant vascular and/or organ extension. The primary lesion is typically found in the uterus, with the most common extrauterine sites being pelvic/broad ligament vessels, and less often inferior vena cava, right heart chambers, and pulmonary vasculature. Extrauterine involvement can result in direct mass effect or vascular obstruction with associated clinical sequelae. Read More

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http://dx.doi.org/10.1097/PGP.0000000000000127DOI Listing
March 2015
15 Reads

Primary malignant lymphoma of the uterus and broad ligament: a case report and review of literature.

Onco Targets Ther 2015 29;8:265-8. Epub 2015 Jan 29.

Department of Hematology and Oncology (Key Department of Jiangsu Medicine), Zhongda Hospital, Medical School, Southeast University, Nanjing, Jiangsu Province, People's Republic of China.

Primary malignant lymphoma of the uterus and broad ligament is rare. Here, we present a rare case of primary diffuse large B-cell lymphoma (DLBCL) of uterus and broad ligament in a 63-year-old female. The patient presenting with lower abdominal distention was referred to our hospital. Read More

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http://dx.doi.org/10.2147/OTT.S78171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321664PMC
February 2015
14 Reads

Optical clearing in dense connective tissues to visualize cellular connectivity in situ.

PLoS One 2015 12;10(1):e0116662. Epub 2015 Jan 12.

Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, United States of America.

Visualizing the three-dimensional morphology and spatial patterning of cells embedded deep within dense connective tissues of the musculoskeletal system has been possible only by utilizing destructive techniques. Here we utilize fructose-based clearing solutions to image cell connectivity and deep tissue-scale patterning in situ by standard confocal microscopy. Optical clearing takes advantage of refractive index matching of tissue and the embedding medium to visualize light transmission through a broad range of bovine and whole mount murine tissues, including cartilage, bone, and ligament, of the head and hindlimb. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116662PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291226PMC
December 2015
20 Reads

Pregnancies and live births after 20 transplantations of cryopreserved ovarian tissue in a single center.

Fertil Steril 2015 Feb 6;103(2):462-8. Epub 2014 Dec 6.

Department of Gynecology and Obstetrics, Erlangen University Hospital, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen, Germany.

Objective: To report the results of 20 orthotopic retransplantations of cryopreserved ovarian tissue after cancer treatment.

Design: Retrospective analysis.

Setting: Tertiary gynecology department. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00150282140230
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http://dx.doi.org/10.1016/j.fertnstert.2014.10.045DOI Listing
February 2015
8 Reads

[Clinicopathologic features of intravenous leiomyomatosis with intracardiac extension].

Zhonghua Bing Li Xue Za Zhi 2014 Jun;43(6):408-11

Department of Pathology, Beijing Anzhen Hospital, Capital Medical University; Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, China.

Objective: To investigate clinicopathological features, immunophenotype and differential diagnosis of intravenous leiomyomatosis with intracardiac extension.

Methods: Clinical manifestations, morphologic features, and immunohistochemical staining were retrospectively analyzed in 19 cases of intravenous leiomyomatosis with intracardiac extension.

Results: The patients' age ranged from 33 to 59 years (mean 44 years). Read More

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June 2014
11 Reads

Advanced biomatrix designs for regenerative therapy of periodontal tissues.

J Dent Res 2014 Dec 19;93(12):1203-11. Epub 2014 Aug 19.

Department of Nanobiomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 330-714, Republic of Korea Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan 330-714, Republic of Korea Department of Biomaterials Science, College of Dentistry, Dankook University, Cheonan 330-714, Republic of Korea

Periodontitis is an inflammatory disease that causes loss of the tooth-supporting apparatus, including periodontal ligament, cementum, and alveolar bone. A broad range of treatment options is currently available to restore the structure and function of the periodontal tissues. A regenerative approach, among others, is now considered the most promising paradigm for this purpose, harnessing the unique properties of stem cells. Read More

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http://journals.sagepub.com/doi/10.1177/0022034514540682
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http://dx.doi.org/10.1177/0022034514540682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462799PMC
December 2014
15 Reads

Management of the neglected and healed bilateral cervical facet dislocation.

Eur Spine J 2014 Aug 7;23(8):1612-6. Epub 2014 May 7.

Spine Service, Department of Orthopaedic Surgery, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.

Introduction: There is limited literature on the management of neglected healed (fused) bilateral cervical facet dislocation. The authors report a case of a middle aged male who developed a bilateral facet dislocation but only sought treatment 14 months post injury when he experienced pain and deformity in the cervical spine.

Case Report: A 42-year-old male was pushed into a 1. Read More

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http://dx.doi.org/10.1007/s00586-014-3318-7DOI Listing
August 2014
59 Reads