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    15124 results match your criteria British medical journal Clinical research ed.[Journal]

    1 OF 303

    Uptake of immunisation in district health authorities in England.
    Br Med J (Clin Res Ed) 1988 Jun;296(6639):1775-8
    Department of General Practice, St Mary's Hospital Medical School, Lisson Grove Health Centre, London.
    The uptakes of immunisation in the district health authorities in England were studied for the years 1983-5. Multiple regression analysis showed that the factors significantly associated with a low uptake of immunisation were mainly related to social conditions, particularly overcrowding of households and population density. Of the service factors, high proportions of elderly and singlehanded general practitioners and high average list sizes were also associated with a low uptake of immunisation in some of the analyses. Read More

    Mentally abnormal prisoners on remand: II--Comparison of services provided by Oxford and Wessex regions.
    Br Med J (Clin Res Ed) 1988 Jun;296(6639):1783-4
    Maudsley Hospital, London.
    Most regional health authorities have or plan to have secure units for treating mentally abnormal offenders. A retrospective study was carried out to compare the effectiveness of the health care services for men remanded to Winchester prison from Oxford and Wessex regions over the five years 1979-83. Thirty seven (30%) of 124 prisoners from Oxford region were rejected for treatment compared with 36 (16%) of the 220 men from Wessex region. Read More

    Mentally abnormal prisoners on remand: I--Rejected or accepted by the NHS?
    Br Med J (Clin Res Ed) 1988 Jun;296(6639):1779-82
    Maudsley Hospital, London.
    Increasing numbers of mentally abnormal offenders are sentenced to prison. The decision to treat or imprison them is influenced by the attitudes of consultant psychiatrists and their staff. The process whereby those decisions were made and the willingness of consultants to offer treatment were investigated. Read More

    A randomised dose ranging study of recombinant tissue plasminogen activator in acute myocardial infarction.
    Br Med J (Clin Res Ed) 1988 Jun;296(6639):1768-71
    Regional Medical Cardiology Centre, Royal Victoria Hospital, Belfast.
    To assess the thrombolytic efficacy and the effect on the systemic fibrinolytic system of recombinant tissue plasminogen activator doses of 20 mg, 50 mg, and 100 mg were compared in a randomised study. Tissue plasminogen activator was infused intravenously over 90 minutes in 50 consecutive patients with acute myocardial infarction of four hours' duration or less; on average the infusion was started 135 minutes (range 20 to 240) after the onset of pain. The affected artery was patent at the end of the 90 minute infusion in 14/17 (82%) of those who received 100 mg, 12/17 (71%) of those who received 50 mg, and 8/16 (50%) of those who received 20 mg. Read More

    Improvement of in vitro fertilisation after treatment with buserelin, an agonist of luteinising hormone releasing hormone.
    Br Med J (Clin Res Ed) 1988 Jun;296(6639):1765-8
    Institute of Obstetrics and Gynaecology, Royal Postgraduate Medical School, Hammersmith Hospital, London.
    Treatment with buserelin, an agonist of luteinising hormone releasing hormone, and human menopausal gonadotrophin was compared with the conventional treatment of clomiphene citrate and human menopausal gonadotrophin in the outcome of in vitro fertilisation. Seventy seven infertile women had 83 cycles of treatment with buserelin and human menopausal gonadotrophin, and concurrently another 328 infertile women were treated with clomiphene citrate and human menopausal gonadotrophin. Seven (8%) cycles were cancelled owing to inadequate super-ovulation or ovarian hyperstimulation in the women receiving buserelin and 103 (31%) were cancelled because of poor follicular development in those receiving clomiphene citrate. Read More

    Carcinoma in situ of the testis: aneuploid cells in semen.
    Br Med J (Clin Res Ed) 1988 Jun;296(6639):1762-4
    University Department of Obstetrics and Gynaecology, Rigshospitalet, Copenhagen, Denmark.
    The content of cellular DNA in ejaculates from eight patients with carcinoma in situ of the testis and 26 controls without evidence of testicular neoplasia was studied by flow cytometry. An aneuploid cell population with a ploidy value similar to that found for carcinoma in situ cells was detected in seminal fluid from four of the eight men with carcinoma in situ but in none of the controls. One year after orchidectomy or local irradiation in these four men no aneuploid cells were found in the semen. Read More

    Effect of intravesical mitomycin C on recurrence of newly diagnosed superficial bladder cancer: interim report from the Medical Research Council Subgroup on Superficial Bladder Cancer (Urological Cancer Working Party).
    Br Med J (Clin Res Ed) 1988 Jun;296(6639):1759-61
    Royal Infirmary, Edinburgh.
    A randomised control trial of intravesical instillation of mitomycin C was conducted in 457 patients with cancer of the bladder that was confined to the submucosa on histological examination. The events studied were the recurrence free rate, the recurrence rate/year, and the number of new tumours developing/year. At the initial cystoscopy the tumours were completely resected and the patients randomised to have no instillation of mitomycin C, a single instillation of 40 mg in 40 ml of water at that cystoscopy, or a single instillation and then four further instillations. Read More

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