143,444 results match your criteria British journal of community nursing[Journal]


Gaze allocation in face-to-face communication is affected primarily by task structure and social context, not stimulus-driven factors.

Cognition 2018 Dec 14;184:28-43. Epub 2018 Dec 14.

Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, the Netherlands; Developmental Psychology, Utrecht University, Utrecht, the Netherlands; Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands.

Gaze allocation to human faces has recently been shown to be greatly dependent on the social context. However, what has not been considered explicitly here, is how gaze allocation may be supportive of the specific task that individuals carry out. In the present study, we combined these two insights. Read More

View Article
December 2018

Guidelines Versus Guidelines.

Ann Intern Med 2018 Dec;169(12):895-896

Johns Hopkins Bayview Medical Center, Baltimore, Maryland (T.F.).

View Article
December 2018

Long-Term Outcomes Among Patients Discharged From the Hospital With Moderate Anemia: A Retrospective Cohort Study.

Ann Intern Med 2018 Dec 18. Epub 2018 Dec 18.

Kaiser Permanente Northern California, Oakland, California (D.G.M., C.L., P.K., V.X.L., G.J.E.).

Background: Randomized clinical trial findings support decreased red blood cell (RBC) transfusion and short-term tolerance of in-hospital anemia. However, long-term outcomes related to changes in transfusion practice have not been described.

Objective: To describe the prevalence of anemia at and after hospital discharge and associated morbidity and mortality events. Read More

View Article
December 2018
1 Read

A Laboratory Evaluation of Contextual Factors Affecting Ratings of Speech in Noise: Implications for Ecological Momentary Assessment.

Ear Hear 2018 Dec 14. Epub 2018 Dec 14.

School of Audiology & Speech Sciences, University of British Columbia, Vancouver, British Columbia, Canada.

Objectives: As hearing aid outcome measures move from retrospective to momentary assessments, it is important to understand how contextual factors influence subjective ratings. Under laboratory-controlled conditions, we examined whether subjective ratings changed as a function of acoustics, response timing, and task variables.

Design: Eighteen adults (age 21 to 85 years; M = 51. Read More

View Article
December 2018

The Value of Imaging-The Case for Coronary Computed Tomography Angiography.

J Thorac Imaging 2019 Jan;34(1):2-3

Department of Medical Imaging and Division of Cardiology, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.

View Article
January 2019

Cost-Utility Study of the Economics of Bunion Correction Surgery.

Foot Ankle Int 2018 Dec 17:1071100718815663. Epub 2018 Dec 17.

3 Department of Orthopaedics, University of British Columbia, Vancouver, BC, Canada.

Background:: Bunion correction surgery is a very common procedure to improve patients' pain and physical function attributable to a misaligned first metatarsophalangeal joint. The objective of this study was to apply a health utility framework to estimate the cost utility of bunion correction surgery.

Methods:: Patients were prospectively recruited from the population of patients seen in a lower-extremity orthopedic clinic and scheduled for isolated bunion surgery. Read More

View Article
December 2018

Minimum Information about an Uncultivated Virus Genome (MIUViG).

Nat Biotechnol 2018 Dec 17. Epub 2018 Dec 17.

US Department of Energy Joint Genome Institute, Walnut Creek, California, USA.

We present an extension of the Minimum Information about any (x) Sequence (MIxS) standard for reporting sequences of uncultivated virus genomes. Minimum Information about an Uncultivated Virus Genome (MIUViG) standards were developed within the Genomic Standards Consortium framework and include virus origin, genome quality, genome annotation, taxonomic classification, biogeographic distribution and in silico host prediction. Community-wide adoption of MIUViG standards, which complement the Minimum Information about a Single Amplified Genome (MISAG) and Metagenome-Assembled Genome (MIMAG) standards for uncultivated bacteria and archaea, will improve the reporting of uncultivated virus genomes in public databases. Read More

View Article
December 2018
1 Read

VNUT and VMAT2 segregate within sympathetic varicosities and localize near preferred Cav2 isoforms in the rat tail artery.

Am J Physiol Heart Circ Physiol 2019 Jan 12;316(1):H89-H105. Epub 2018 Oct 12.

Department of Biomedical Physiology and Kinesiology, Simon Fraser University , Burnaby, British Columbia , Canada.

ATP and norepinephrine (NE) are coreleased from peripheral sympathetic nerve terminals. Whether they are stored in the same vesicles has been debated for decades. Preferential dependence of NE or ATP release on Ca influx through specific voltage-gated Ca channel (Cav2) isoforms suggests that NE and ATP are stored in separate vesicle pools, but simultaneous imaging of NE and ATP containing vesicles within single varicosities has not been reported. Read More

View Article
January 2019
1 Read

Death of the King: The Introduction of Vaccination into Nepal in 1816.

Authors:
Susan Heydon

Med Hist 2019 Jan;63(1):24-43

This article explores the introduction of smallpox vaccination into Nepal in 1816 at the request of the Nepalese government; the king, however, was not vaccinated, contracted the disease and died. British hopes that vaccination would be extended throughout the country did not eventuate. The article examines the significance of this early appearance of vaccination in Nepal for both Nepalese and British, and relates it to the longer history of smallpox control and eventual eradication. Read More

View Article
January 2019

'If We Are to Believe the Psychologists …': Medicine, Psychoanalysis and Breastfeeding in Britain, 1900-55.

Authors:
Katharina Rowold

Med Hist 2019 Jan;63(1):61-81

In 1942, the British Minister of Health commissioned a report from the newly established Advisory Committee on Mothers and Young Children into 'What can be done to intensify the effort to secure more breast feeding of infants?'. To make their case, the members of the sub-committee put in charge of the report sought expert testimony on the benefits of breastfeeding. They consulted medical officers of health, maternity and child-welfare officers, health visitors, midwives, obstetricians, paediatricians and a physician in private practice. Read More

View Article
January 2019

Effect of dialect on phonological analysis.

Clin Linguist Phon 2018 Dec 16:1-22. Epub 2018 Dec 16.

a Division of Graduate Medical Studies , National University of Singapore , Singapore.

It is important to understand a child's language background, to ensure appropriate assessment, diagnosis and treatment of speech sound disorders. Singapore is home to various cultures and languages, and local speech norms are needed to provide an accurate reference for assessing phonological disorders in the local population. This study aims to establish normative data and better understand the English phonological development of English-Mandarin bilingual preschoolers in Singapore, aged 3; 6-4; 5 years. Read More

View Article
December 2018

Distinction of Condylomata Acuminata from Vulvar Vestibular Papules or Pearly Penile Papules Using Ki-67 Immunostaining.

J Cutan Med Surg 2018 Dec 17:1203475418819992. Epub 2018 Dec 17.

1 Departments of Dermatology and Skin Science, University of British Columbia, Vancouver, Canada.

Background:: Ki-67 is an immunohistochemical stain used as a nuclear proliferation marker. It is nonspecific, and is expressed in all active phases of the cell cycle. Vulvar vestibular papules in women and pearly penile papules in men are benign fibrous papules on the genitals, are noninfectious, and do not require treatment. Read More

View Article
December 2018
1 Read

Bottoms up: the role of gut microbiota in brain health.

Environ Microbiol 2018 Dec 16. Epub 2018 Dec 16.

Department of Biochemistry & Molecular Biology, University of British Columbia, Vancouver.

The gut microbiota affects many aspects of human health, and research, especially over the past decade, is demonstrating that the brain is no exception. This review summarizes existing human observational studies of the microbiota in brain health and neurological conditions at all ages, as well as animal studies that are advancing the field beyond correlation and into causality. Potential mechanisms by which the brain and the gut microbiota are connected are explored, including inflammation, bacterially-produced metabolites and neurotransmitters, and specific roles for individual microbes. Read More

View Article
December 2018

Risk of Parkinson's disease in patients with neovascular age-related macular degeneration.

J Curr Ophthalmol 2018 Dec 5;30(4):365-367. Epub 2018 Sep 5.

Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada.

Purpose: To examine the risk of developing Parkinson's Disease (PD) in patients who are newly diagnosed with neovascular age-related macular degeneration (nAMD).

Methods: This was a cohort study using the British Columbia (BC) Retinal Disease Database. Data from 2009 to 2013 was accessed. Read More

View Article
December 2018

Resilience and learning from insurance firms: Dataset on British long-term insurance market performance.

Data Brief 2018 Dec 24;21:2360-2366. Epub 2018 Nov 24.

Portsmouth Business School, University of Portsmouth, PO1 3DE Portsmouth, UK.

This data article revealed data about the UK long-term insurance market performance for over a decade. The data was acquired from the ABI and contains important trading results (i.e. Read More

View Article
December 2018

Latent profile analysis of young adolescents' physical activity across locations on schooldays.

J Transp Health 2018 Sep 8;10:304-314. Epub 2018 Jun 8.

University of California San Diego, La Jolla, California USA.

Purpose: To investigate whether adolescents cluster into profiles based on where they accumulate moderate-to-vigorous physical activity (MVPA), if overall MVPA differs across profiles, and if walking to school and participant and neighborhood characteristics explain profile membership.

Methods: Adolescents (N=528; mean age=14.12±1. Read More

View Article
September 2018

Just flip it!-CRT implantation in a patient with dextrocardia and situs inversus totalis.

J Arrhythm 2018 Dec 6;34(6):656-658. Epub 2018 Oct 6.

Heart Rhythm Services - St-Paul's Hospital University of British Columbia Vancouver BC Canada.

Implantation of a cardiac resynchronization therapy (CRT) device in patients with congenital heart disease may be challenging because of the particular underlying anatomy. We present the case of a right-sided transvenous implantation of a dual-chamber CRT-D device in a patient with situs inversus totalis and mirror image dextrocardia. To facilitate our anatomic orientation and to overcome unusual hand-eye coordination problems, we decided to flip the fluoroscopic image projection by 180° (right-left), creating the optical impression of a "normalized" heart position (levocardia). Read More

View Article
December 2018

Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization.

Front Immunol 2018 30;9:2825. Epub 2018 Nov 30.

Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Pulmonary tuberculosis (TB), which is caused by (, remains a global pandemic, despite the widespread use of the parenteral live attenuated Bacillus Calmette-Guérin (BCG) vaccine during the past decades. Mucosal administration of next generation TB vaccines has great potential, but developing a safe and efficacious mucosal vaccine is challenging. Hence, understanding the biodistribution and pharmacokinetics of mucosal vaccines is essential for shaping the desired immune response and for optimal spatiotemporal targeting of the appropriate effector cells in the lungs. Read More

View Article
November 2018

Hyaluronan and Its Interactions With Immune Cells in the Healthy and Inflamed Lung.

Front Immunol 2018 29;9:2787. Epub 2018 Nov 29.

Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada.

Hyaluronan is a hygroscopic glycosaminoglycan that contributes to both extracellular and pericellular matrices. While the production of hyaluronan is essential for mammalian development, less is known about its interaction and function with immune cells. Here we review what is known about hyaluronan in the lung and how it impacts immune cells, both at homeostasis and during lung inflammation and fibrosis. Read More

View Article
November 2018

Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need.

Alzheimers Dement 2018 Dec 13. Epub 2018 Dec 13.

Department of Pharmacology & Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA. Electronic address:

Alzheimer's disease and related dementias (ADRDs) are a global crisis facing the aging population and society as a whole. With the numbers of people with ADRDs predicted to rise dramatically across the world, the scientific community can no longer neglect the need for research focusing on ADRDs among underrepresented ethnoracial diverse groups. The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART; alz. Read More

View Article
December 2018

Assessment and treatment of pediatric behavioral sleep disorders in Canada.

Sleep Med 2018 Nov 26. Epub 2018 Nov 26.

University of Alberta, Edmonton, AB, Canada.

Objectives/background: This paper outlines the current state of Canadian training, clinical services, research, and advocacy initiatives related to non-respiratory sleep disorders, with a specific focus on insomnia, the most common sleep problem in children.

Methods: Information for this narrative review was collected from peer-reviewed publications, web-resources, and personal communications and experiences.

Results: It is estimated that approximately one-third of Canadian children and youth present with insomnia, and that this is impacting their physical and mental health, as well as learning in school. Read More

View Article
November 2018

A Horizon Scan of Emerging Issues for Global Conservation in 2019.

Trends Ecol Evol 2018 Dec 5. Epub 2018 Dec 5.

Conservation Science Group, Department of Zoology, Cambridge University, The David Attenborough Building, Pembroke Street, Cambridge, CB2 3QZ, UK.

We present the results of our tenth annual horizon scan. We identified 15 emerging priority topics that may have major positive or negative effects on the future conservation of global biodiversity, but currently have low awareness within the conservation community. We hope to increase research and policy attention on these areas, improving the capacity of the community to mitigate impacts of potentially negative issues, and maximise the benefits of issues that provide opportunities. Read More

View Article
December 2018

Clinical research networks and assessing pandemic severity.

Lancet Glob Health 2019 Jan;7(1):e33

University of Western Australia, Perth, WA, Australia; International Severe and Acute Respiratory and Emerging Infections Consortium, Oxford, UK.

View Article
January 2019

Independent and combined effects of improved water, sanitation, and hygiene, and improved complementary feeding, on child stunting and anaemia in rural Zimbabwe: a cluster-randomised trial.

Lancet Glob Health 2019 Jan;7(1):e132-e147

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore MD, USA; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe; Blizard Institute, Queen Mary University of London, London, UK.

Background: Child stunting reduces survival and impairs neurodevelopment. We tested the independent and combined effects of improved water, sanitation, and hygiene (WASH), and improved infant and young child feeding (IYCF) on stunting and anaemia in in Zimbabwe.

Methods: We did a cluster-randomised, community-based, 2 × 2 factorial trial in two rural districts in Zimbabwe. Read More

View Article
January 2019

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.

Authors:
Nasim Mavaddat Kyriaki Michailidou Joe Dennis Michael Lush Laura Fachal Andrew Lee Jonathan P Tyrer Ting-Huei Chen Qin Wang Manjeet K Bolla Xin Yang Muriel A Adank Thomas Ahearn Kristiina Aittomäki Jamie Allen Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Kristan J Aronson Paul L Auer Päivi Auvinen Myrto Barrdahl Laura E Beane Freeman Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Hiltrud Brauch Michael Bremer Hermann Brenner Adam Brentnall Ian W Brock Angela Brooks-Wilson Sara Y Brucker Thomas Brüning Barbara Burwinkel Daniele Campa Brian D Carter Jose E Castelao Stephen J Chanock Rowan Chlebowski Hans Christiansen Christine L Clarke J Margriet Collée Emilie Cordina-Duverger Sten Cornelissen Fergus J Couch Angela Cox Simon S Cross Kamila Czene Mary B Daly Peter Devilee Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Lorraine Durcan Miriam Dwek Diana M Eccles Arif B Ekici A Heather Eliassen Carolina Ellberg Christoph Engel Mikael Eriksson D Gareth Evans Peter A Fasching Jonine Figueroa Olivia Fletcher Henrik Flyger Asta Försti Lin Fritschi Marike Gabrielson Manuela Gago-Dominguez Susan M Gapstur José A García-Sáenz Mia M Gaudet Vassilios Georgoulias Graham G Giles Irina R Gilyazova Gord Glendon Mark S Goldberg David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Ute Hamann Susan E Hankinson Elaine F Harkness Steven N Hart Wei He Alexander Hein Jane Heyworth Peter Hillemanns Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Anthony Howell Guanmengqian Huang Keith Humphreys David J Hunter Milena Jakimovska Anna Jakubowska Wolfgang Janni Esther M John Nichola Johnson Michael E Jones Arja Jukkola-Vuorinen Audrey Jung Rudolf Kaaks Katarzyna Kaczmarek Vesa Kataja Renske Keeman Michael J Kerin Elza Khusnutdinova Johanna I Kiiski Julia A Knight Yon-Dschun Ko Veli-Matti Kosma Stella Koutros Vessela N Kristensen Ute Krüger Tabea Kühl Diether Lambrechts Loic Le Marchand Eunjung Lee Flavio Lejbkowicz Jenna Lilyquist Annika Lindblom Sara Lindström Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Jan Lubiński Michael P Lux Robert J MacInnis Tom Maishman Enes Makalic Ivana Maleva Kostovska Arto Mannermaa Siranoush Manoukian Sara Margolin John W M Martens Maria Elena Martinez Dimitrios Mavroudis Catriona McLean Alfons Meindl Usha Menon Pooja Middha Nicola Miller Fernando Moreno Anna Marie Mulligan Claire Mulot Victor M Muñoz-Garzon Susan L Neuhausen Heli Nevanlinna Patrick Neven William G Newman Sune F Nielsen Børge G Nordestgaard Aaron Norman Kenneth Offit Janet E Olson Håkan Olsson Nick Orr V Shane Pankratz Tjoung-Won Park-Simon Jose I A Perez Clara Pérez-Barrios Paolo Peterlongo Julian Peto Mila Pinchev Dijana Plaseska-Karanfilska Eric C Polley Ross Prentice Nadege Presneau Darya Prokofyeva Kristen Purrington Katri Pylkäs Brigitte Rack Paolo Radice Rohini Rau-Murthy Gad Rennert Hedy S Rennert Valerie Rhenius Mark Robson Atocha Romero Kathryn J Ruddy Matthias Ruebner Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Fredrick Schumacher Peter Schürmann Lukas Schwentner Christopher Scott Rodney J Scott Caroline Seynaeve Mitul Shah Mark E Sherman Martha J Shrubsole Xiao-Ou Shu Susan Slager Ann Smeets Christof Sohn Penny Soucy Melissa C Southey John J Spinelli Christa Stegmaier Jennifer Stone Anthony J Swerdlow Rulla M Tamimi William J Tapper Jack A Taylor Mary Beth Terry Kathrin Thöne Rob A E M Tollenaar Ian Tomlinson Thérèse Truong Maria Tzardi Hans-Ulrich Ulmer Michael Untch Celine M Vachon Elke M van Veen Joseph Vijai Clarice R Weinberg Camilla Wendt Alice S Whittemore Hans Wildiers Walter Willett Robert Winqvist Alicja Wolk Xiaohong R Yang Drakoulis Yannoukakos Yan Zhang Wei Zheng Argyrios Ziogas Alison M Dunning Deborah J Thompson Georgia Chenevix-Trench Jenny Chang-Claude Marjanka K Schmidt Per Hall Roger L Milne Paul D P Pharoah Antonis C Antoniou Nilanjan Chatterjee Peter Kraft Montserrat García-Closas Jacques Simard Douglas F Easton

Am J Hum Genet 2018 Dec 5. Epub 2018 Dec 5.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.

Stratification of women according to their risk of breast cancer based on polygenic risk scores (PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, optimized for prediction of estrogen receptor (ER)-specific disease, from the largest available genome-wide association dataset and to empirically validate the PRSs in prospective studies. The development dataset comprised 94,075 case subjects and 75,017 control subjects of European ancestry from 69 studies, divided into training and validation sets. Read More

View Article
December 2018
1 Read

The Content and Correlates of Belief in Karma Across Cultures.

Pers Soc Psychol Bull 2018 Dec 16:146167218808502. Epub 2018 Dec 16.

1 The University of British Columbia, Vancouver, Canada.

Karmic beliefs, centered on the expectation of ethical causation within and across lifetimes, appear in major world religions as well as spiritual movements around the world, yet they remain an underexplored topic in psychology. In three studies, we assessed the psychological predictors of Karmic beliefs among participants from culturally and religiously diverse backgrounds, including ethnically and religiously diverse students in Canada, and broad national samples of adults from Canada, India, and the United States (total N = 8,996). Belief in Karma is associated with, but not reducible to, theoretically related constructs including belief in a just world, belief in a moralizing God, religious participation, and cultural context. Read More

View Article
December 2018

Medical Students Learn Professionalism in Near-Peer Led, Discussion-Based Small Groups.

Teach Learn Med 2018 Dec 15:1-12. Epub 2018 Dec 15.

d Undergraduate Medical Education , Queen's University , Kingston , Ontario , Canada.

Problem: Medical educators recognize that professionalism is difficult to teach to students in lecture-based or faculty-led settings. An underused but potentially valuable alternative is to enroll near-peers to teach professionalism.

Intervention: We describe a novel near-peer curriculum on professionalism developed at Queen's University School of Medicine. Read More

View Article
December 2018

Degree of optical polarization as a tool for detecting melanoma: proof of principle.

J Biomed Opt 2018 Dec;23(12):1-7

University of British Columbia, School of Biomedical Engineering, Vancouver, Canada.

Determining the optical polarization properties of a skin lesion is a proposed method to differentiate melanoma from other skin lesions. We developed an in vivo Stokes polarimetry probe that fires a laser of known polarization at the skin and measures the Stokes parameters of the backscattered light in one shot. From these measured Stokes parameters, we can calculate the degree of polarization (DOP). Read More

View Article
December 2018
1 Read

Cranioplasties following craniectomies in children-a multicenter, retrospective cohort study.

Childs Nerv Syst 2018 Dec 15. Epub 2018 Dec 15.

Department of Neurosurgery, Division of Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Heidelberglaan 100, room G03.124, 3484 CX, Utrecht, The Netherlands.

Objective: Complications following pediatric cranioplasty after craniectomy with either autologous bone flaps or cranial implants are reported to be common, particularly bone flap resorption. However, only sparse data are available regarding cranioplasty strategies, complications, and outcomes. This manuscript describes a Canadian-Dutch multicenter pediatric cohort study with autografts and cranial implant cranioplasties following craniectomies for a variety of indications. Read More

View Article
December 2018
1 Read

Functional, cognitive and physical outcomes 3 years after minor lacunar or cortical ischaemic stroke.

J Neurol Neurosurg Psychiatry 2018 Dec 15. Epub 2018 Dec 15.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK

Objective: Many studies examining stroke outcomes focus on more severe strokes or have short follow-up periods, so the long-term outcomes post-minor ischaemic stroke are unclear.

Methods: We recruited participants from inpatient and outpatient services with a lacunar or minor cortical ischaemic stroke (National Institutes of Health Stroke Scale score <8) and assessed current and premorbid cognitive functioning (Addenbrooke's Cognitive Examination-Revised (ACE-R), National Adult Reading Test (NART)), physical functioning (Timed Get Up and Go (TUG), 9-Hole Peg Test (9HPT)), dependency (modified Rankin Scale (mRS)), depression (Beck's Depression Inventory) in-person and remotely (Stroke Impact Scale).

Results: We followed up 224/264 participants at 3 years (mean age at index stroke=67, 126 (56%) men, 25 non-contactable, 15 declined): 66/151 (44%) had cognitive impairment, mean ACE-R 88 (SD 9, range 54-100/100), 61/156 (39%) had depression and 26/223 (12%) were dependent (mRS=3-5). Read More

View Article
December 2018

"It's about bloody time": Perceptions of people who use drugs regarding drug law reform.

Int J Drug Policy 2018 Dec 13;64:40-46. Epub 2018 Dec 13.

Drug Policy Modelling Program, University of New South Wales, 22-32 King Street, Randwick NSW 2031, Australia.

Background: In Australia and elsewhere, the impacts of drug prohibition have sparked a critical dialogue about the state of current drug laws. While a range of 'experts' have offered their opinion and participation in these deliberations, the voices of the affected community have largely been excluded. This study aimed to gather the opinions and preferences of people who use drugs about the current or alternative models of drug laws, in addition to how they think drug laws could be changed Author Conflict of Interest Declaration. Read More

View Article
December 2018
1 Read

Best practices for teaching pharmacology to undergraduate nursing students: A systematic review of the literature.

Nurse Educ Today 2018 Dec 7;74:15-24. Epub 2018 Dec 7.

Faculty of Health and Social Development, School of Nursing, University of British Columbia, Kelowna, BC, Canada.

Objective: In this systematic review we describe best practices for teaching pharmacology to undergraduate baccalaureate nursing students based on the available evidence. Numerous teaching strategies employed in undergraduate pharmacology courses for nursing students have been summarized and compared for their impact on pharmacology knowledge retention, application of pharmacology theory to practice, and student satisfaction. Future directions for research are discussed. Read More

View Article
December 2018

CONSERVE Your Energy and Resources.

Authors:
David E Newby

JACC Cardiovasc Imaging 2018 Dec 6. Epub 2018 Dec 6.

British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland, United Kingdom. Electronic address:

View Article
December 2018

Women's perspectives about cannabis use during pregnancy and the postpartum period: An integrative review.

Prev Med 2018 Dec 12. Epub 2018 Dec 12.

University of British Columbia, Vancouver, BC, Canada.

Cannabis is the most commonly used illicit drug among general and pregnant populations. Despite recommendations to abstain from cannabis use, its use is increasing during the perinatal period. In this integrative review, we aim to understand women's perspectives about the health aspects of perinatal cannabis use. Read More

View Article
December 2018
1 Read

Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis Worldwide.

Gastroenterology 2018 Dec 12. Epub 2018 Dec 12.

Unit of Internal Medicine and Hepatology (UIMH), Department of Medicine - DIMED, University of Padova, Padova, Italy. Electronic address:

Background And Aims: Bacterial infections are common and life-threatening in patients with cirrhosis. Little is known about the epidemiology of bacterial infections in different regions. We performed a multicenter prospective intercontinental study to assess the prevalence and outcomes of bacterial and fungal infections in patients with cirrhosis. Read More

View Article
December 2018
1 Read
16.716 Impact Factor

British Association of Dermatologists guidelines for the management of hidradenitis suppurativa (acne inversa) 2018.

Br J Dermatol 2018 Dec 15. Epub 2018 Dec 15.

British Association of Dermatologists, Willan House, 4 Fitzroy Square, London, W1T 5HQ, U.K.

The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the management of hidradenitis suppurativa (HS). The document aims to:. offer an appraisal of all relevant literature up to July 2018, focusing on any key developments. Read More

View Article
December 2018
1 Read

Probable reverse zoonosis of influenza A(H1N1)pdm 09 in a striped skunk (Mephitis mephitis).

Zoonoses Public Health 2018 Dec 14. Epub 2018 Dec 14.

Wildlife and Habitat Branch, BC Ministry of Forests, Lands, Natural Resource Operations and Rural Development, Nanaimo, British Columbia, Canada.

Striped skunks (skunks) are susceptible to respiratory infection by influenza A viruses (IAV). As they are common synanthropes, maintenance of IAV in skunks could provide a source of infection for humans. We previously studied the nasal turbinates, lungs and faeces of 50 free-ranging skunks for the presence of IAV and identified two individuals with influenza A(H1N1)pdm09 infection during the 2009/2010 and 2013/2014 flu seasons. Read More

View Article
December 2018

Lean mass and lower limb muscle function in relation to hip strength, geometry and fracture risk indices in community-dwelling older women.

Osteoporos Int 2018 Dec 14. Epub 2018 Dec 14.

Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

In a population-based sample of British women aged over 70 years old, lean mass and peak lower limb muscle force were both independently associated with hip strength and fracture risk indices, thereby suggesting a potential benefit of promoting leg muscle strengthening exercise for the prevention of hip fractures in postmenopausal women.

Introduction: To investigate cross-sectional associations of lean mass and physical performance, including lower limb muscle function, with hip strength, geometry and fracture risk indices (FRIs) in postmenopausal women.

Methods: Data were from the Cohort of Skeletal Health in Bristol and Avon. Read More

View Article
December 2018

Serum rantes, transforming growth factor-β1 and interleukin-6 levels correlate with cardiac muscle fibrosis in patients with aortic valve stenosis.

J Physiol Pharmacol 2018 Aug 9;69(4). Epub 2018 Dec 9.

Department of Interventional Cardiology, Jagiellonian University College of Medicine and the John Paul II Hospital, Cracow, Poland.

Regulated on Activation Normal T Expressed and Secreted (RANTES) chemokine is involved in the initiation of inflammation and immune-cell recruitment. Interleukin -6 (IL-6) is used as a general index of severity of the chronic inflammatory process. Finally, transforming growth factor-β (TGF-β) is an immune biomarker potentially involved in the regulation of valve fibrosis and calcification. Read More

View Article
August 2018
1 Read

Born to be Wise: a population registry data linkage protocol to assess the impact of modifiable early-life environmental exposures on the health and development of children.

BMJ Open 2018 Dec 14;8(12):e026954. Epub 2018 Dec 14.

Fielding School of Public Health, University of California, Los Angeles, California, USA.

Introduction: Deficiencies in childhood development is a major global issue and inequalities are large. The influence of environmental exposures on childhood development is currently insufficiently explored. This project will analyse the impact of various modifiable early life environmental exposures on different dimensions of childhood development. Read More

View Article
December 2018
1 Read

Understanding cauda equina syndrome: protocol for a UK multicentre prospective observational cohort study.

BMJ Open 2018 Dec 14;8(12):e025230. Epub 2018 Dec 14.

Department for Clinical Neurosciences, Western General Hospital, Edinburgh, UK.

Introduction: Cauda equina syndrome (CES) is a potentially devastating condition caused by compression of the cauda equina nerve roots. This can result in bowel, bladder and sexual dysfunction plus lower limb weakness, numbness and pain. CES occurs infrequently, but has serious potential morbidity and medicolegal consequences. Read More

View Article
December 2018

Cultural validation of the Addenbrooke's Cognitive Examination Version III Urdu for the British Urdu-speaking population: a qualitative assessment using cognitive interviewing.

BMJ Open 2018 Dec 14;8(12):e021057. Epub 2018 Dec 14.

Centre for Primary Care, The University of Manchester, Manchester, UK.

Objectives: Our research determined whether the Addenbrooke's Cognitive Examination Version III (ACE-III) Urdu eliminated cultural bias through a qualitative assessment of its understanding and acceptability within the British Urdu-speaking population, employing cognitive interviews.

Method: We aimed to recruit 25 participants fluent in speaking and writing Urdu, over the age of 60 years, able to give informed consent and who did not have a history of cognitive impairment. Participants were administered the ACE-III Urdu, and cognitive interviews were conducted, which involve obtaining verbal data on the individual's perception of the assessment overall, their understanding of the mental processes behind how they interpreted questions within the assessment and how they produced appropriate responses. Read More

View Article
December 2018

A Call for Improved Reporting of Human Islet Characteristics in Research Articles.

Diabetes 2018 Dec 14. Epub 2018 Dec 14.

Institute of Cellular Medicine, Faculty of Clinical Medical Sciences, Newcastle University, Newcastle upon Tyne, U.K.

View Article
December 2018

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

Lancet Respir Med 2018 Dec 11. Epub 2018 Dec 11.

Division of Respiratory Medicine, National Institute for Health Research, Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK. Electronic address:

Background: Few genetic studies that focus on moderate-to-severe asthma exist. We aimed to identity novel genetic variants associated with moderate-to-severe asthma, see whether previously identified genetic variants for all types of asthma contribute to moderate-to-severe asthma, and provide novel mechanistic insights using expression analyses in patients with asthma.

Methods: In this genome-wide association study, we used a two-stage case-control design. Read More

View Article
December 2018
2 Reads

Movies in the magnet: Naturalistic paradigms in developmental functional neuroimaging.

Dev Cogn Neurosci 2018 Nov 20. Epub 2018 Nov 20.

The Child Study Center at New York University Langone Medical Center, 1 Park Avenue, New York, NY, 10016, United States; Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY, 10962, United States.

The use of movie-watching as an acquisition state for functional connectivity (FC) MRI has recently enabled multiple groups to obtain rich data sets in younger children with both substantial sample sizes and scan durations. Using naturalistic paradigms such as movies has also provided analytic flexibility for these developmental studies that extends beyond conventional resting state approaches. This review highlights the advantages and challenges of using movies for developmental neuroimaging and explores some of the methodological issues involved in designing pediatric studies with movies. Read More

View Article
November 2018

Similarity of Repeated Falls in Older Long-Term Care Residents: Do the Circumstances of Past Falls Predict Those of Future Falls?

J Am Med Dir Assoc 2018 Dec 11. Epub 2018 Dec 11.

Injury Prevention and Mobility Laboratory, Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, Canada; Centre for Hip Health and Mobility, University of British Colombia, Vancouver, Canada; School of Engineering Science, Simon Fraser University, Burnaby, Canada.

View Article
December 2018

The top 100: A review of the most cited articles in Surgery.

Cir Esp 2018 Dec 11. Epub 2018 Dec 11.

Servicio de Cirugía General y Digestiva, Hospital Universitario de Guadalajara, Guadalajara, España.

Introduction: We performed a study of the top 100 most cited articles in the five general surgery journals with the highest impact according to Journal Citation Report.

Methods: We selected the five journals with the highest impact in 2015: Annals of Surgery, British Journal of Surgery, JAMA Surgery, Surgery, and Journal of the American College of Surgeons. In January 2017, using the Web of Science application, we performed a search of all articles published by these journals and identified the 100 most cited articles (top 100). Read More

View Article
December 2018
1 Read

Spatial and Temporal Variations of Six Criteria Air Pollutants in Fujian Province, China.

Int J Environ Res Public Health 2018 12 13;15(12). Epub 2018 Dec 13.

College of Landscape Architecture, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, China.

Air pollution has become a critical issue in the urban areas of southeastern China in recent years. A complete understanding of the tempo-spatial characteristics of air pollution can help the public and governmental bodies manage their lives and work better. In this study, data for six criteria air pollutants (including particulate matter (PM, PM), carbon monoxide (CO), sulfur dioxide (SO₂), nitrogen dioxide (NO₂) and ozone (O₃)) from 37 sites in nine major cities within Fujian Province, China were collected between January 2015 to December 2016, and analyzed. Read More

View Article
December 2018
2 Reads

Hydrostatic High-Pressure Post-Processing of Specimens Fabricated by DLP, SLA, and FDM: An Alternative for the Sterilization of Polymer-Based Biomedical Devices.

Materials (Basel) 2018 Dec 13;11(12). Epub 2018 Dec 13.

Department of Mechanical Engineering and Advanced Materials, Tecnologico de Monterrey, Monterrey 64849, NL, Mexico.

In this work, we assess the effects of sterilization in materials manufactured using additive manufacturing by employing a sterilization technique used in the food industry. To estimate the feasibility of the hydrostatic high-pressure (HHP) sterilization of biomedical devices, we have evaluated the mechanical properties of specimens produced by commercial 3D printers. Evaluations of the potential advantages and drawbacks of Fused Deposition Modeling (FDM), Digital Light Processing (DLP) technology, and Stereolithography (SLA) were considered for this study due to their widespread availability. Read More

View Article
December 2018