16,627 results match your criteria British Journal of Radiology[Journal]


Fluoroscopic Self-Expandable metallic stent placement for treating postoperative nonanastomotic strictures in the proximal small bowel: A 15-Year single institution experience.

Br J Radiol 2019 Apr 24:20180957. Epub 2019 Apr 24.

3 Department of Radiologic Technology, Cheju Halla University , Jeju , Republic of Korea.

Objectives: To evaluate the efficacy and safety of fluoroscopic self-expandable metallic stent (SEMS) placement for treating postoperative nonanastomotic strictures in the proximal small bowel.

Methods: Data from eight consecutive patients (mean age, 63.8 ± 6. Read More

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http://dx.doi.org/10.1259/bjr.20180957DOI Listing

Quantitative evaluation of Beta-Amyloid brain PET imaging in dementia: A comparison between two commercial software packages and the clinical report.

Br J Radiol 2019 Apr 24:20181025. Epub 2019 Apr 24.

2 Department of Nuclear Medicine, Imperial College Healthcare NHS Trust, Charing Cross Hospital, Fulham Palace Road , London , UK.

Objectives: To compare commercially available image analysis tools Hermes BRASS and Siemens with clinical assessment in 18F-Florbetapir PET scans.

Methods: 225 scans were reported by clinicians and quantified using two software packages. Scans were classified into type A (typical features) or non-type A (atypical features) for both positive and negative scans. Read More

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http://dx.doi.org/10.1259/bjr.20181025DOI Listing

Optimisation and usefulness of quantitative analysis of F-florbetapir PET.

Br J Radiol 2019 Apr 24:20181020. Epub 2019 Apr 24.

1 Radiological Sciences Unit, Imperial College Healthcare NHS Trust, Charing Cross Hospital, Fulham Palace Road , London , UK.

Objectives: This study investigates the usefulness of quantitative SUVR thresholds on sub types of typical (type A) and atypical (non-type A) positive (Aβ+) and negative (Aβ-) F-florbetapir scans and aims to optimise the thresholds.

Methods: Clinical F-florbetapir scans ( = 100) were categorised by sub type and visual reads were performed independently by three trained readers. Inter reader agreement and reader-to-reference agreement were measured. Read More

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http://dx.doi.org/10.1259/bjr.20181020DOI Listing

Contrast enhanced digital mammography versus magnetic resonance imaging for accurate measurement of the size of breast cancer.

Br J Radiol 2019 Apr 24:20180929. Epub 2019 Apr 24.

1 Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of medicine , Seoul , Korea.

Objective: To compare the accuracy of contrast-enhanced digital mammography (CEDM) and MRI, including maximal intensity projection (MIP) images, for measuring the tumour size of breast cancer.

Methods: We included 52 females (mean age, 50.9 years) with surgery due to breast cancer, and measured maximum diameter of main mass on mediolateral oblique (MLO) and craniocaudal (CC) views of mammography and CEDM; sagittal, axial MIP images, and early dynamic contrast-enhanced MRI (CEMRI) before surgery. Read More

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http://dx.doi.org/10.1259/bjr.20180929DOI Listing

Prostate cancer dose-response, fractionation sensitivity and repopulation parameters evaluation from 25 international radiotherapy outcome data sets.

Br J Radiol 2019 Apr 24:20180823. Epub 2019 Apr 24.

5 Radiation Therapy, Candiolo Cancer Institute - FPO , IRCCS, Candiolo (To) , Italy.

Objective: This study was undertaken to model the biochemical free survival at 5 years and to evaluate the parameters defining dose-response curve, dose-fractionation radiosensitivity and repopulation.

Methods: It was carried out a literature search on Pubmed to retrieve data sets of patients treated with external beam radiation therapy of 1.8-4. Read More

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http://dx.doi.org/10.1259/bjr.20180823DOI Listing

The clinical utility of phase-based respiratory gated PET imaging based on visual feedback with a head-mounted display system.

Br J Radiol 2019 Apr 24:20180233. Epub 2019 Apr 24.

3 Department of Radiological Sciences, Graduate School of Medicine, Tokyo Metropolitan University , Tokyo.

Objective: We developed a new respiratory-gated positron emission tomography (PET) imaging method (RGV-PET) that phase-based respiratory gated PET imaging (RG-PET) combine with head-mounted display (HMD)-guided "visual feedback." The purpose of this study was to investigate whether RGV-PET is effective for stabilizing the quantitativeness of tumors in the phase-based respiratory gating method.

Methods: Of the 41 enrolled patients with hepatobiliary or pancreatic cancer, 20 patients underwent RGV-PET and the remaining 21 patients underwent RG-PET. Read More

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http://dx.doi.org/10.1259/bjr.20180233DOI Listing

Dose-painted volumetric modulated arc therapy of high-grade glioma using 3,4-dihydroxy-6-[F]fluoro-l-phenylalanine positron emission tomography.

Br J Radiol 2019 Apr 24:20180901. Epub 2019 Apr 24.

3 Department of Radiation Oncology, BC Cancer - Vancouver , Vancouver , British Columbia, Canada.

Objectives: To determine whether dose painting with volumetric modulated arc therapy (VMAT) for high-grade gliomas using 3,4-dihydroxy-6-[F]fluoro- l -phenylalanine (F-FDOPA) positron emission tomography (PET) could achieve dose-escalated coverage of biological target volumes (BTVs) without increasing the dose to cranial organs at risk.

Methods: Ten patients with high-grade gliomas underwent CT, MRI, and F-FDOPA PET/CT images for postoperative radiation therapy planning. Two VMAT plans were retrospectively generated for each patient: a conventional plan with 60 Gy in 30 fractions to the planning target volume (PTV) delineated on MRI and a dose-escalated plan with a maximum dose of 80 Gy in 30 fractions to BTVs. Read More

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http://dx.doi.org/10.1259/bjr.20180901DOI Listing

Quantitative study of liver hemodynamic changes in rats with small-for-size syndrome by the 4D-CT perfusion technique.

Br J Radiol 2019 Apr 24:20180847. Epub 2019 Apr 24.

1 Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University , Guangzhou , China.

Objective: The microcirculatory hemodynamic changes of small-for-size syndrome (SFSS) are still unclear. In this study, they were investigated by four-dimensional CT perfusion (4D-CTP) technique.

Methods: The sham group, 50, 60, 70 and 80 % partial hepatectomy (PH) rat groups were established. Read More

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http://dx.doi.org/10.1259/bjr.20180847DOI Listing

Machine-learning identifies parkinson's disease patients based on resting-state between-network functional connectivity.

Br J Radiol 2019 Apr 17:20180886. Epub 2019 Apr 17.

1 Department of Diagnostic and Interventional Radiology, University Dusseldorf, Medical Faculty , Dusseldorf , Germany.

Objectives: Evaluation of a data-driven, model-based classification approach to discriminate idiopathic Parkinson's disease (PD) patients from healthy controls (HC) based on between-network connectivity in whole-brain resting-state functional MRI (rs-fMRI).

Methods: Whole-brain rs-fMRI (EPI/TR = 2.2  s/TE = 30  ms/flip angle = 90°/resolution = 3. Read More

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http://dx.doi.org/10.1259/bjr.20180886DOI Listing

Towards a standard MRI protocol for multiple sclerosis across the UK.

Br J Radiol 2019 Apr 17:20180926. Epub 2019 Apr 17.

7 Department of Diagnostic and Interventional Neuroradiology, Hannover Medical School , Hannover , Germany.

Multiple sclerosis (MS) is a chronic inflammatory demyelinating and degenerative disease of the central nervous system. It is the most common non-traumatic cause of chronic disability in young adults. An early and accurate diagnosis, and effective disease modifying treatment (DMT) are key elements of optimum care for people with MS (pwMS). Read More

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April 2019
6 Reads

Clinical trials in molecular radiotherapy-Tribulations and Triumphs Report of the NCRI CTRad meeting held at the Lift Islington, 8 June 2018.

Br J Radiol 2019 Apr 14:20190117. Epub 2019 Apr 14.

2 Joint Department of Physics, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research , Sutton, Surrey , UK.

It has been almost a decade since the commentary Molecular radiotherapy - the radionuclide raffle? by Gaze and Flux (2010) . The overarching feeling then was that no individual or organisation has taken up the challenge, nationally or internationally, of championing molecular radiotherapy in all its aspects. Here, we report on the recent NCRI-CTRad (Clinical Trials in Molecular Radiotherapy-Tribulations and Triumphs) meeting, held in London on the 8 June 2018. Read More

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https://www.birpublications.org/doi/10.1259/bjr.20190117
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April 2019
1 Read

Quantitative pancreatic MRI: a pathology-based review.

Br J Radiol 2019 Apr 14:20180941. Epub 2019 Apr 14.

1 University College London (UCL) Centre for Medical Imaging, Division of Medicine, UCL , London , UK.

MRI plays an important role in the clinical management of pancreatic disorders and interpretation is reliant on qualitative assessment of anatomy. Conventional sequences capturing pancreatic structure can however be adapted to yield quantitative measures which provide more diagnostic information, with a view to increasing diagnostic accuracy, improving patient stratification, providing robust non-invasive outcome measures for therapeutic trials and ultimately personalizing patient care. In this review, we evaluate the use of established techniques such as secretin-enhanced MR cholangiopancreatography, diffusion-weighted imaging, T , T * and fat fraction mapping, but also more experimental methods such as MR elastography and arterial spin labelling, and their application to the assessment of diffuse pancreatic disease (including chronic, acute and autoimmune pancreatitis/IgG4 disease, metabolic disease and iron deposition disorders) and cystic/solid focal pancreatic masses. Read More

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http://dx.doi.org/10.1259/bjr.20180941DOI Listing
April 2019
1 Read

Cyclo-oxygenase-2 expression is associated with mean standardised uptake value on 18F-Fluorodeoxyglucose positron emission tomography in oesophageal adenocarcinoma.

Br J Radiol 2019 Apr 14:20180668. Epub 2019 Apr 14.

1 Department of Radiology, University Hospital of Wales, Heath , UK.

Objectives: This pilot study investigated the association of four PET image features and cyclo-oxygenase-2 (COX-2) expression in patients with oesophageal adenocarcinoma. The prognostic significance of these biomarkers was also assessed.

Methods: Fifty consecutive patients [median age = 68 (range 47 - 84), males = 45) with oesophageal adenocarcinoma had PET/CT staging between January 2011 and July 2015. Read More

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https://www.birpublications.org/doi/10.1259/bjr.20180668
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April 2019
1 Read

Factors associated with pseudoaneurysm development and necessity for re-intervention: a single centre study.

Br J Radiol 2019 Apr 14:20180893. Epub 2019 Apr 14.

2 Vascular radiology department, University Hospitals of Leicester NHS Trust and University of Leicester , Leicestershire, United Kingdom.

Objectives: Evaluate the factors associated with pseudoaneurysm development and morphology. Measure ultrasound-guided thrombin injection (UGTI) and surgical treatment outcomes for pseudoaneurysms, and the necessity for post-primary intervention (re-intervention).

Methods: Retrospective analysis of ultrasound scans and CT angiography of peripheral pseudoaneurysm interventions from February 2011 to April 2017. Read More

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http://dx.doi.org/10.1259/bjr.20180893DOI Listing
April 2019
1.533 Impact Factor

Clinical F-FDG and Amyloid Brain Positron Emission Tomography/CT in the Investigation of Cognitive Impairment: Where Are We Now?

Br J Radiol 2019 Apr 14:20181027. Epub 2019 Apr 14.

2 Department of Nuclear Medicine, Imperial College Healthcare NHS Trust, London UK.

The number of people living with dementia is increasing, but as yet there remains no cure or disease-modifying treatment. This review aims to help readers understand the role of F-FDG PET/CT imaging in the investigation of cognitive impairment and how the advent of amyloid PET/CT imaging may hold the key to radically changing management of the most common form of dementia - Alzheimer's disease. The indications for F-FDG PET/CT and amyloid PET/CT imaging in cognitive impairment are outlined. Read More

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http://dx.doi.org/10.1259/bjr.20181027DOI Listing

Towards understanding neural network signatures of motor skill learning in parkinson's disease and healthy aging.

Br J Radiol 2019 Apr 14:20190071. Epub 2019 Apr 14.

1 Department of Rehabilitation Sciences, KU Leuven , Leuven , Belgium.

In the past decade, neurorehabilitation has been shown to be an effective therapeutic supplement for patients with Parkinson's disease (PD). However, patients still experience severe problems with the consolidation of learned motor skills. Knowledge on the neural correlates underlying this process is thus essential to optimize rehabilitation for PD. Read More

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http://dx.doi.org/10.1259/bjr.20190071DOI Listing

Preclinical neuroimaging of gene-environment interactions in psychiatric disease.

Br J Radiol 2019 Apr 14:20180885. Epub 2019 Apr 14.

1 Neuroscience Training Program, University of Wisconsin-Madison, Wisconsin Institutes for Medical Research , Madison , USA.

Psychiatric disease is one of the leading causes of disability worldwide. Despite the global burden and need for accurate diagnosis and treatment of mental illness, psychiatric diagnosis remains largely based on patient-reported symptoms, allowing for immense symptomatic heterogeneity within a single disease. In renewed efforts towards improved diagnostic specificity and subsequent evaluation of treatment response, a greater understanding of the underlying of the neuropathology and neurobiology of neuropsychiatric disease is needed. Read More

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http://dx.doi.org/10.1259/bjr.20180885DOI Listing

Multiparametric MRI appearances of primary granulomatous prostatitis.

Br J Radiol 2019 Apr 9:20180075. Epub 2019 Apr 9.

4 Department of Radiology, Southend University Hospital, Westcliff-on-Sea , Essex , UK.

Objective: Radiological features of granulomatous prostatitis (GP) overlap with those of prostate adenocarcinoma. Identification of specific GP features may aid diagnosis. We aimed to evaluate the multiparametric MRI (mpMRI) features of GP. Read More

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http://dx.doi.org/10.1259/bjr.20180075DOI Listing

Beam direction arrangement using a superconducting rotating gantry in carbon ion treatment for pancreatic cancer.

Br J Radiol 2019 Apr 24:20190101. Epub 2019 Apr 24.

2 Research Center for Charged Particle Therapy, National Institute of Radiological Sciences , Chiba , Japan.

Objectives: Carbon ion radiotherapy provides a concentrated dose distribution to the target and has several advantages over photon radiotherapy. This study aimed to evaluate the optimal beam direction in carbon ion pencil beam scanning and compare dose distributions between the rotating gantry system (RGS) and fixed-beam port system (FBPS).

Methods: Patients with locally advanced pancreatic cancer were randomly selected. Read More

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http://dx.doi.org/10.1259/bjr.20190101DOI Listing
April 2019
3 Reads

Early results and volumetric analysis after spot-scanning proton therapy with concomitant hyperthermia in large inoperable sacral chordomas.

Br J Radiol 2019 Apr 3:20180883. Epub 2019 Apr 3.

1 Center for Proton Therapy, Paul Scherrer Institute, ETH Domain, Villigen PSI , Switzerland.

Objectives: : Large inoperable sacral chordomas show unsatisfactory local control rates even when treated with high dose proton therapy (PT). The aim of this study is assessing feasibility and reporting early results of patients treated with PT and concomitant hyperthermia (HT).

Methods: : Patients had histologically proven unresectable sacral chordomas and received 70Gy(RBE) in 2. Read More

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https://www.birpublications.org/doi/10.1259/bjr.20180883
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April 2019
3 Reads
1.533 Impact Factor

Realising the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer.

Br J Radiol 2019 Apr 1:20180670. Epub 2019 Apr 1.

1 Institute of Cancer Research and Royal Marsden National Health Service Foundation Trust , Sutton, Surrey , United Kingdom.

Computerised tomography based radiotherapy workflow is limited by poor soft tissue definition in the pelvis and reliance on rigid registration methods. Current image guided radiotherapy and adaptive radiotherapy models therefore have limited ability to improve clinical outcomes. The advent of magnetic resonance image guided radiotherapy solutions provides the opportunity to overcome these limitations with the potential to deliver online real time magnetic resonance imaging based plan adaptation on a daily basis, a true "plan of the day". Read More

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https://www.birpublications.org/doi/10.1259/bjr.20180670
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April 2019
6 Reads

Introduction to quantitative susceptibility mapping and susceptibility weighted imaging.

Br J Radiol 2019 Apr 1:20181016. Epub 2019 Apr 1.

2 Radiology, Cambridge University Hospitals , Cambridge , United Kingdom.

Quantitative Susceptibility Mapping (QSM) and Susceptibility Weighted Imaging (SWI) are magnetic resonance imaging techniques that measure and display differences in the magnetisation that is induced in tissues, i.e. their magnetic susceptibility, when placed in the strong external magnetic field of an MRI system. Read More

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http://dx.doi.org/10.1259/bjr.20181016DOI Listing

Fatigue in radiology: A fertile area for future research.

Br J Radiol 2019 Apr 1:20190043. Epub 2019 Apr 1.

1 Warwick Medical School, The University of Warwick , Coventry , England.

Fatigue in radiologists may be responsible for a large number of medical errors. This review describes the latest research on fatigue in radiology. This includes measurement methods, and recent evidence on how fatigue affects accuracy in laboratory test conditions and in clinical practice. Read More

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http://dx.doi.org/10.1259/bjr.20190043DOI Listing

Added value of contrast -Enhanced Mammography in Assessment of Breast Asymmetries.

Br J Radiol 2019 Apr 1:20180245. Epub 2019 Apr 1.

1 Department of Radiology Faculty of Medicine, Kasr El Aini hospital, Cairo University , Egypt.

Objective:: To evaluate the clinical performance of contrast-enhanced spectral mammography (CESM) on asymmetries detected on a mammogram (MG).

Methods:: This study was approved by the Scientific Research Review Board of the Radiology Department, and waiver of informed consent was applied for the uses of data of the included cases. The study included 125 female patients,33 (26. Read More

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https://www.birpublications.org/doi/10.1259/bjr.20180245
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http://dx.doi.org/10.1259/bjr.20180245DOI Listing
April 2019
5 Reads

The evolving role of image-guided biopsy and specimen fixation-update from an oncology setting.

Br J Radiol 2019 Apr 9:20180971. Epub 2019 Apr 9.

1 Department of Radiology, University Hospital Southampton , Southampton , UK.

Image-guided biopsy is well established in clinical practice, however a recent shift towards "personalized medicine" and genomic research, particularly in the oncology setting, has resulted in a greater demand for tissue, not only at preliminary diagnosis but at multiple time points in the patient's journey. Research into the molecular pathobiology underpinning cancer development and progression continues to identify diagnostic, predictive and prognostic biomarkers that help determine and guide treatment both at the outset, and as patient's progress or recur. This extensive tissue analysis however, necessitates larger tissue cores and a greater number of biopsies with correct fixation of the specimens obtained. Read More

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http://dx.doi.org/10.1259/bjr.20180971DOI Listing

The advanced radiotherapy network (ART-NET) UK lung stereotactic ablative radiotherapy survey: national provision and a focus on image guidance.

Br J Radiol 2019 Apr 24:20180988. Epub 2019 Apr 24.

1 Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust , Leeds , England.

Objective: Stereotactic ablative radiotherapy (SABR) has become the standard of care for suitable patients with peripherally located early stage non-small cell lung cancer. Lung SABR requires strict image-guided radiotherapy (IGRT) protocols to ensure its safe delivery. The aim of this survey was to provide an assessment of current lung SABR practice in the UK. Read More

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http://dx.doi.org/10.1259/bjr.20180988DOI Listing
April 2019
3 Reads

Utilization of volumetric magnetic resonance imaging for baseline and surveillance imaging in Neuro-oncology.

Br J Radiol 2019 03 29:20190059. Epub 2019 Mar 29.

1 Department of Neuroradiology, National Cancer Research Institute Metastases and Meningioma subgroup of the Brain Clinical Studies Group and The Walton Centre NHS Foundation Trust , Liverpool , England.

The acquisition of volumetric post-contrast MRI has clear advantages in the interpretation of neuro-oncology studies but has yet to find its way into routine clinical practice beyond planning scans for surgery and radiotherapy. This commentary briefly highlights the benefits of these techniques whilst dispelling some of the perceived disadvantages. Read More

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http://dx.doi.org/10.1259/bjr.20190059DOI Listing
March 2019
2 Reads
1.533 Impact Factor

Changes in liver morphology in patients with extrahepatic portal venous obstruction: a retrospective magnetic resonance imaging study.

Br J Radiol 2019 Apr 9:20180890. Epub 2019 Apr 9.

2 Radiodiagnosis and Imaging, PGIMER , Chandigarh , India.

Objective: To investigate the liver parenchymal changes on MRI in patients with extrahepatic portal venous obstruction (EHPVO).

Methods: This was a retrospective evaluation of the MRI studies in patients with EHPVO between January 2016 and April 2018. The diagnosis of EHPVO in each case had been established on the basis of clinical and Doppler parameters. Read More

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http://dx.doi.org/10.1259/bjr.20180890DOI Listing
April 2019
5 Reads

Dual energy computed tomography virtual monoenergetic imaging: technique and clinical applications.

Br J Radiol 2019 Apr 9:20180546. Epub 2019 Apr 9.

2 Department of Diagnostic and Interventional Radiology, Division of Experimental Imaging, University Hospital Frankfurt , Frankfurt , Germany.

Dual energy CT (DECT) has evolved into a commonly applied imaging technique in clinical routine due to its unique post-processing opportunities for improved evaluation of all body areas. Reconstruction of virtual monoenergetic imaging (VMI) series has shown beneficial effects for both non-contrast and contrast-enhanced DECT due to the flexibility to calculate low-keV VMI reconstructions to increase contrast and iodine attenuation, or to compute high-keV VMI reconstructions to reduce beam-hardening artefacts. The goal of this review article is to explain the technical background of VMI and noise-optimized VMI+ algorithms and to give an overview of useful clinical applications of the VMI technique in DECT of various body regions. Read More

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http://dx.doi.org/10.1259/bjr.20180546DOI Listing

Multiparametric MRI-guided dose boost to dominant intraprostatic lesions in CT-based High-dose-rate prostate brachytherapy.

Br J Radiol 2019 May 9;92(1097):20190089. Epub 2019 Apr 9.

1 Department of Radiation Oncology and Winship Cancer Institute, Emory University , Atlanta, GA , USA.

Objective: The purpose of this study is to investigate the dosimetric feasibility of delivering focal dose to multiparametric (mp) MRI-defined DILs in CT-based high-dose-rate (HDR) prostate brachytherapy with MR/CT registration and estimate its clinical benefit.

Methods: We retrospectively investigated a total of 17 patients with mp-MRI and CT images acquired pre-treatment and treated by HDR prostate brachytherapy. 21 dominant intraprostatic lesions (DILs) were contoured on mp-MRI and propagated to CT images using a deformable image registration method. Read More

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http://dx.doi.org/10.1259/bjr.20190089DOI Listing
May 2019
1.533 Impact Factor

Establishing MRI-guided prostate intervention at a UK Centre.

Br J Radiol 2019 Apr 24:20180918. Epub 2019 Apr 24.

1 University Hospital Southampton NHS Foundation Trust , Hampshire.

Objectives: To describe our preliminary experience in establishing an MRI suite capable to deliver targeted prostate biopsy and cryoablation.

Methods: This article includes a description of the necessary infrastructure alterations, scanning sequence suggestions, anaesthetic advice, and practical procedural considerations. We aim to examine the anticipated issues most UK centres would encounter and offer our experience in overcoming them. Read More

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http://dx.doi.org/10.1259/bjr.20180918DOI Listing

Stereotactic body radiotherapy to the prostate and pelvic lymph nodes: A detailed dosimetric analysis of a phase II prospective trial.

Br J Radiol 2019 Apr 3:20181001. Epub 2019 Apr 3.

1 Department of Radiation Oncology, University of California , Los Angeles , USA.

Objective:: To evaluate the dosimetric ramifications of simultaneously irradiating the prostate and pelvic lymph nodes (PLNs) with a stereotactic body radiotherapy approach based on rigid registration to intraprostatic markers (IPMs).

Methods And Materials:: Nineteen patients received concurrent SBRT to the prostate and PLNs on a phase II clinical trial. The translational and rotation shifts required for rigid registration to bony anatomy and changes in bladder and rectal anatomy were compared between patients with > 90% and < 90% coverage of the nodal clinical target volume (CTV ) as drawn on fractional kilovoltage cone-beam CTs. Read More

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http://dx.doi.org/10.1259/bjr.20181001DOI Listing

Reduced motion and improved rectal dosimetry through endorectal immobilization for prostate stereotactic body radiotherapy.

Br J Radiol 2019 Apr 24:20190056. Epub 2019 Apr 24.

2 Liverpool Cancer Therapy Centre , Liverpool , Australia.

Objective: PROMETHEUS (ACTRN12615000223538) is a multicentre clinical trial investigating the feasibility of 19 Gy in 2 fractions of stereotactic body radiotherapy (SBRT) as a boost technique for prostate cancer. The objective of this substudy was to evaluate intrafraction motion using cine MRI and assess the dosimetric impact of using a rectal displacement device (RDD).

Methods: The initial 10 patients recruited underwent planning CT and MRI, with and without a RDD. Read More

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http://dx.doi.org/10.1259/bjr.20190056DOI Listing
April 2019
1 Read

Volumetric versus single slice measurements of core abdominal muscle for sarcopenia.

Br J Radiol 2019 May 9;92(1097):20180434. Epub 2019 Apr 9.

1 Leeds Vascular Institute, Leeds General Infirmary , Leeds , UK.

Objective: We investigated whether total psoas muscle area (TPMA) was representative of the total psoas muscle volume (TPMV). Secondly, we assessed whether there was a relationship between the two commonly used single slice measurements of sarcopenia, TPMA and total abdominal muscle area (TAMA).

Methods: Pre-operative CT imaging of 110 patients undergoing elective endovascular aneurysm repair were analyzed by two trained independent observers. Read More

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http://dx.doi.org/10.1259/bjr.20180434DOI Listing
May 2019
3 Reads
1.533 Impact Factor

Patients with metallic coils and Amplatzer vascular plugs used to treat pulmonary arteriovenous malformations since 1984 can safely undergo magnetic resonance imaging.

Br J Radiol 2019 Apr 24:20180752. Epub 2019 Apr 24.

2 Respiratory Medicine, Imperial College Healthcare NHS Trust , London , UK.

Objective: To examine the MRI safety of metallic coils and Amplatzer vascular plugs. Currently, concern regarding MR safety of devices used to treat pulmonary arteriovenous malformations (PAVMs) causes delays in performing emergency MRI in patients presenting with acute neurological symptoms.

Methods: A retrospective audit was performed on all patients who underwent PAVM embolization at Hammersmith Hospital, London UK between 1984 and 2017. Read More

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http://dx.doi.org/10.1259/bjr.20180752DOI Listing
April 2019
1 Read

Iodine load reduction in dual-energy spectral CT portal venography with low energy images combined with adaptive statistical iterative reconstruction.

Br J Radiol 2019 Mar 21:20180414. Epub 2019 Mar 21.

1 Department of Radiology, Affiliated Hospital of Shaanxi University of Chinese Medicine , Xianyang , Shaanxi, China.

Objective:: To study the application of using low energy images combined with adaptive statistical iterative reconstruction (ASiR) in dual-energy spectral CT portal venography (CTPV) to reduce iodine load.

Methods:: 41 patients for CTPV were prospectively and randomly divided into two groups. Group A ( n = 21) used conventional 120kVp scanning protocol with contrast dose at 0. Read More

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http://dx.doi.org/10.1259/bjr.20180414DOI Listing

Feasibility of an ADC-based radiomics model for predicting pelvic lymph node metastases in patients with stage IB-IIA cervical squamous cell carcinoma.

Br J Radiol 2019 May 1;92(1097):20180986. Epub 2019 Apr 1.

1 Department of Radiology, Cancer Hospital of China Medical University, Liaoning cancer hospital & institute Shenyang , Liaoning , China.

Objectives: To investigate the prediction value of a radiomics model based on apparent diffusion coefficient (ADC) maps for pelvic lymph node metastasis (PLNM) in patients with stage IB-IIA cervical squamous cell carcinoma (CSCC).

Methods: A total of 153 stage IB-IIA CSCC patients who underwent preoperative MRI including DWI from January 2015 to October 2017 were retrospectively studied and divided into a training cohort ( = 102) and a validation cohort ( = 51). Radiomics features were extracted from the ADC maps. Read More

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http://dx.doi.org/10.1259/bjr.20180986DOI Listing
May 2019
2 Reads

Stiffness of prostate gland measured by transrectal real-time shear wave elastography for detection of prostate cancer: a feasibility study.

Br J Radiol 2019 May 26;92(1097):20180970. Epub 2019 Mar 26.

2 Department of Ultrasound Medicine, Baoji Municipal Centre Hospital , Baoji, Shanxi Province , China.

Objective: This study aimed to evaluate the value of the Young's modulus obtained by transrectal real-time shear wave elastography (SWE) for detection of prostate cancer (PCa).

Methods: 215 patients underwent SWE in six identical planes before biopsy guided with transrectal ultrasonography. The Young's modulus of the entire prostate gland was defined as the mean of the results in these planes. Read More

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http://dx.doi.org/10.1259/bjr.20180970DOI Listing

Neuroimaging in Psychiatry and Neurodevelopment: why the emperor has no clothes.

Br J Radiol 2019 Mar 15:20180910. Epub 2019 Mar 15.

2 Department of Radiology and Imaging Sciences, University of Utah , Salt Lake City, UT.

Neuroimaging has been a dominant force in guiding research into psychiatric and neurodevelopmental disorders for decades, yet researchers have been unable to formulate sensitive or specific imaging tests for these conditions. The search for neuroimaging biomarkers has been constrained by limited reproducibility of imaging techniques, limited tools for evaluating neurochemistry, heterogeneity of patient populations not defined by brain-based phenotypes, limited exploration of temporal components of brain function, and relatively few studies evaluating developmental and longitudinal trajectories of brain function. Opportunities for development of clinically impactful imaging metrics include longer duration functional imaging data sets, new engineering approaches to mitigate suboptimal spatiotemporal resolution, improvements in image post-processing and analysis strategies, big data approaches combined with data sharing of multisite imaging samples, and new techniques that allow dynamical exploration of brain function across multiple timescales. Read More

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March 2019
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Linac-based stereotactic body radiation therapy vs moderate hypofractionated radiotherapy in prostate cancer: propensity-score based comparison of outcome and toxicity.

Br J Radiol 2019 May 29;92(1097):20190021. Epub 2019 Mar 29.

1 Radiotherapy and Radiosurgery, Humanitas Clinical and Research Center - IRCCS , Rozzano, Via Manzoni 56 , Italy.

Objective: Prostate cancer represents the second most common malignancy in the world and majority of patients have diagnosis of localized disease. The aim of the present study was to compare two cohorts of patients treated with moderate hypofractionation (MHRT) or stereotactic body radiation therapy (SBRT).

Methods: We included patients treated between 2010 and 2015. Read More

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May 2019
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Assessing a small field of view hybrid gamma camera for perioperative iodine-125 seed localisation.

Br J Radiol 2019 Apr 24:20190020. Epub 2019 Apr 24.

1 Radiological Sciences and Precision Imaging Beacon, School of Medicine, University of Nottingham , UK.

Objective: To examine the imaging capability of a novel small field of view hybrid gamma camera (HGC) using I seeds prior to surgical use.

Methods: The imaging performance of the camera system was assessed quantitatively and qualitatively at different source depths, source to collimator distances (SCD), activity levels, acquisition times and source separations, utilising bespoke phantoms.

Results: The system sensitivity and spatial resolution of the HGC for I were 0. Read More

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April 2019
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Comparative effectiveness of intensity modulated radiation therapy to 3-dimensional conformal radiation in locally advanced lung cancer: pathological and clinical outcomes.

Br J Radiol 2019 May 1;92(1097):20180960. Epub 2019 Apr 1.

1 Department of Radiation Oncology, Institute Of Oncology, Chaim Sheba Medical Center, Tel Hashomer, Affiliated to Sackler Faculty of Medicine, Tel Aviv University , Ramat Gan , Israel.

Objective: Intensity-modulated radiotherapy (IMRT) has better normal-tissue sparing compared with 3-dimensional conformal radiation (3DCRT). We sought to assess the impact of radiation technique on pathological and clinical outcomes in locally advanced non-small cell lung cancer (LANSCLC) treated with a trimodality strategy.

Methods: Retrospective review of LANSCLC patients treated from August 2012 to August 2018 at Sheba Medical Center, Israel. Read More

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May 2019
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MRI evaluation of pelvis in Mayer-Rokitansky-Kuster-Hauser syndrome: interobserver agreement for surgically relevant structures.

Br J Radiol 2019 May 15;92(1097):20190045. Epub 2019 Mar 15.

1 Department of Radiology and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital , New Delhi , India.

Objectives: Diagnostic role of MRI in Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is well documented. Recent studies have shown the relevance of MRI in detailing the pelvic anatomy, particularly small Mullerian remnants. The results are, however, not consistent and reproducibility of MRI features has not been confirmed. Read More

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May 2019
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Results of re-irradiation for pelvic recurrence in anorectal cancer patients.

Br J Radiol 2019 May 29;92(1097):20180794. Epub 2019 Mar 29.

6 Department of Radiation Oncology, Seoul National University College of Medicine , Seoul , Republic of Korea.

Objective: To evaluate outcomes and toxicity profiles after re-irradiation in patients with pelvic recurrence of anorectal cancer.

Methods: 25 anorectal cancer patients who received re-irradiation for pelvic recurrence between 2005 and 2015 were included. For initial treatment, all patients underwent surgical resection and preoperative or postoperative radiotherapy. Read More

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May 2019
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CT support of cardiac structural interventions.

Br J Radiol 2019 Mar 11:20180707. Epub 2019 Mar 11.

Department of Cardiology, Faculty of Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) , Erlangen , Germany.

Due to its high temporal and isotropic spatial resolution, CT has become firmly established for pre-procedural imaging in the context of structural heart disease interventions. CT allows to very exactly measure dimensions of the target structure, CT can provide information regarding the access route and, as a very valuable addition, volumetric CT data sets can be used to identify fluoroscopic projection angulations to optimally visualize the target structure and place devices. This review provides an overview of current methods and applications of pre-interventional CT to support adult cardiac interventions including transcatheter aortic valve implantation, percutaneous mitral valve intervention, left atrial appendage occlusion and paravalvular leak closure. Read More

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March 2019
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Neuroimaging reward, craving, learning, and cognitive control in substance use disorders: review and implications for treatment.

Br J Radiol 2019 Mar 11:20180942. Epub 2019 Mar 11.

2 Departments of Psychiatry, University of Colorado Anschutz Medical Center , Aurora , CO.

Substance use disorder is a leading causes of preventable disease and mortality. Drugs of abuse cause molecular and cellular changes in specific brain regions and these neuroplastic changes are thought to play a role in the transition to uncontrolled drug use. Neuroimaging has identified neural substrates associated with problematic substance use and may offer clues to reduce its burden on the patient and society. Read More

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Complications from percutaneous microwave ablation of liver tumours: - A pictorial review.

Br J Radiol 2019 Mar 8:20180864. Epub 2019 Mar 8.

1 Department of Radiology, King's College Hospital , London , England.

Percutaneous microwave ablation of liver tumors is a well-established technique that has been proven to be effective in the curative and palliative treatment of small volume primary and secondary liver tumours. Microwave ablation is designed to achieve larger areas of necrosis compared to radiofrequency ablation and has a good safety profile among liver tumor treatments. Mortality is unreported and major complications are rare. Read More

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March 2019
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Percutaneous MR-guided whole-gland prostate cancer cryoablation: safety considerations and oncologic results in 30 consecutive patients.

Br J Radiol 2019 May 9;92(1097):20180965. Epub 2019 Apr 9.

1 Department of Interventional Radiology, University Hospital of Strasbourg, 1 Place de l'Hôpital , Strasbourg , France.

Objective: To assess the safety and oncological efficacy of percutaneous MR-guided whole-gland prostate cancer (PCa) cryoablation (CA).

Methods And Materials: Between July 2009 and January 2018, 30 patients (mean age 72.9 ± 5. Read More

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May 2019
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Tumor thrombus in the venous drainage pathways of primary, recurrent and metastatic disease on routine oncologic imaging studies: beyond hepatocellular and renal cell carcinomas.

Br J Radiol 2019 Apr 24:20180478. Epub 2019 Apr 24.

1 Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center Houston , Texas , USA.

Radiologists routinely evaluate for tumor thrombus in the portal and hepatic veins in patients with hepatocellular carcinoma and in the renal vein and inferior vena cava in patients with renal cell carcinoma. However, tumor thrombus occurs in association with numerous other tumor types, . colorectal carcinoma and pancreatic neuroendocrine tumor. Read More

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April 2019
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Tumor-stromal ratio (TSR) of invasive breast cancer: correlation with multi-parametric breast MRI findings.

Br J Radiol 2019 May 15;92(1097):20181032. Epub 2019 Mar 15.

1 Department of Radiology, Faculty of Medicine, Saga University , Saga , Japan.

Objective: To correlate the tumor-stromal ratio (TSR) of invasive breast cancer and MRI findings.

Methods: This study was approved by our institutional review board. 126 consecutive patients with surgically proven invasive breast cancer were included. Read More

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