17,027 results match your criteria British Journal of Radiology[Journal]


Can t2 blackout effect be A marker of iron accumulation in brains of multiple sclerosis patients ?: A qualitative study.

Br J Radiol 2020 Jul 1:20200552. Epub 2020 Jul 1.

Department of Radiology, Inonu UniversityFaculty of Medicine, Malatya, Turkey.

Objective: T2blackout (TBO) effect, which is a commonfinding in thebrains of multiplesclerosis (MS) patients and older population that are imaged for other reasons on diffusion weighted imagings (DWI) and apparent diffusion coefficent map (ADC) shows the existence of paramagnetic materials in thetissue. Becauseiron is known to accumulate in especially deep graymatter (DGM) structures in MS brains, we aimed to investigate the relationship between TBO and clinico-radiological parameters that may be iron-related in MS.

Methods: We retrospectively reviewed the latest MR images of MS patients on 3 Tesla MR scanner between 2018-2019. Read More

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http://dx.doi.org/10.1259/bjr.20200552DOI Listing

Voxel based evaluation of sequential radiotherapy treatment plans with different dose fractionation schemes.

Br J Radiol 2020 Jul 2:20200197. Epub 2020 Jul 2.

Department of Radiotherapy, PGIMER, Regional Cancer Centre, Chandigarh, India.

Objective: This study presents a methodology for voxel-based evaluation of two phase sequential radiotherapy treatment plans having conventional dose scheme in the first phase and subsequent hypofractionation dose scheme in the second phase based upon different priority [planning target volume (PTV), clinical target volume (CTV) and organs at risk (OAR)] of display modes.

Methods: A case of carcinoma prostate was selected for demonstration. Varian Eclipse treatment planning system (TPS) was used for contouring and planning. Read More

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http://dx.doi.org/10.1259/bjr.20200197DOI Listing

Contrast agent accumulation patterns in chronic interstitial lung disease using 5d MRI.

Br J Radiol 2020 Jun 25:20190121. Epub 2020 Jun 25.

Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at Heidelberg University Hospital, Heidelberg, Germany.

Objectives: To analyse delayed contrast dynamics of fibrotic lesions in interstitial lung disease (ILD) using 5D MRI and to correlate contrast dynamics with disease severity.

Methods: 20 patients (mean age: 71 years; M:F, 13:7), with chronic fibrosing ILD: = 12 idiopathic pulmonary fibrosis (IPF) and = 8 non-IPF, underwent thin-section multislice CT as part of the standard diagnostic workup and additionally MRI of the lung. Two minutes after contrast injection, a radial gradient echo sequence with golden-angle spacing was acquired during 5 min of free-breathing, followed by 5D image reconstruction. Read More

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http://dx.doi.org/10.1259/bjr.20190121DOI Listing

Imaging findings in coronavirus infections: SARS-CoV, MERS-CoV, and SARS-CoV-2.

Br J Radiol 2020 Jul 6:20200515. Epub 2020 Jul 6.

Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine (SKKU-SOM), Seoul, Korea.

During the first two decades of the 21st century, there have been three coronavirus infection outbreaks raising global health concerns by severe acute respiratory syndrome coronavirus (SARS-CoV), the Middle East respiratory syndrome coronavirus (MERS-CoV), and the SARS-CoV-2. Although the reported imaging findings of coronavirus infection are variable and non-specific, the most common initial chest radiograph (CXR) and CT findings are ground-glass opacities and consolidation with peripheral predominance and eventually spread to involve both lungs as the disease progresses. These findings can be explained by the immune pathogenesis of coronavirus infection causing diffuse alveolar damage. Read More

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http://dx.doi.org/10.1259/bjr.20200515DOI Listing

Pulmonary artery enlargement on routine staging F-fluodeoxyglucose positron emission tomography/CT for lung and oesophageal cancer.

Br J Radiol 2020 Jun 25:20200323. Epub 2020 Jun 25.

Department of Nuclear Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

Objective: Pulmonary hypertension (PH) is an underdiagnosed condition associated with poor survival and increased post-operative mortality in lung cancer. CT-based parameters of pulmonary artery enlargement are strong predictors of PH. We used these parameters to investigate pulmonary artery enlargement in lung and oesophageal cancer. Read More

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http://dx.doi.org/10.1259/bjr.20200323DOI Listing

Consensus survey on pre-procedural safety practices in radiological examinations: a multicenter study in seven Asian regions.

Br J Radiol 2020 Jul 2:20200082. Epub 2020 Jul 2.

Department of Radiology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.

Objective: To understand the status of pre-procedural safety practices in radiological examinations at radiology residency training institutions in various Asian regions.

Methods: A questionnaire based on the Joint Commission International Accreditation Standards was electronically sent to 3 institutions each in 10 geographical regions across 9 Asian countries. Questions addressing 45 practices were divided into 3 categories. Read More

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http://dx.doi.org/10.1259/bjr.20200082DOI Listing

Comparison of F-FDG PET-MR and fecal biomarkers in the assessment of disease activity in patients with ulcerative colitis.

Br J Radiol 2020 Jun 24:20200167. Epub 2020 Jun 24.

Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, University of Duisburg-Essen, Am Deimelsberg 34a, 45276 Essen, Germany.

Objective: To compare the diagnostic performance of fecal biomarkers and F-fludeoxyglucose (F-FDG) positron emmision tomography-MR (PET-MR) in the assessment of disease activity in patients with ulcerative colitis.

Methods: This study was conducted under the framework of a single-center clinical trial (clinicaltrials.gov [NCT03781284]). Read More

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http://dx.doi.org/10.1259/bjr.20200167DOI Listing
June 2020
1.533 Impact Factor

The diagnostic performance of CESM and CE-MRI in evaluating the pathological response to neoadjuvant therapy in breast cancer: a systematic review and meta-analysis.

Br J Radiol 2020 Jul 2:20200301. Epub 2020 Jul 2.

Department of Radiology, The Yongchuan Affiliated Hospital, Chongqing Medical University, Yongchuan District, Chongqing, PR China.

Objectives: Neoadjuvant chemotherapy (NAC) is an important method for breast cancer treatment. By monitoring its pathological response, the selection of clinical treatment strategies can be guided. In this study, the meta-analysis was used to compare the accuracy of contrast-enhanced MRI (CE-MRI) and contrast-enhanced spectral mammography (CESM) in detecting the pathological response of NAC. Read More

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http://dx.doi.org/10.1259/bjr.20200301DOI Listing

Linear Mixed-effects models for estimation of pulmonary metastasis growth rate: implications for CT surveillance in patients with sarcoma.

Br J Radiol 2020 Jun 19:20190856. Epub 2020 Jun 19.

Department of Radiology, University of Pennsylvania, 3400 Civic Center, Philadelphia, PA 19104, USA.

Objectives: Sarcoma patients often undergo surveillance chest computed tomography (CT) for detection of pulmonary metastases. No data exists on the optimal surveillance interval for chest CT. The aim of this study was to estimate pulmonary metastasis growth rate in sarcoma patients. Read More

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http://dx.doi.org/10.1259/bjr.20190856DOI Listing

Multimodality imaging of adult rhabdomyosarcoma: the added value of hybrid imaging.

Br J Radiol 2020 Jun 26:20200250. Epub 2020 Jun 26.

Medical Oncology and Hematology Unit, Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy.

Rhabdomyosarcoma (RMS) represents more than 50% of paediatric soft tissue tumours. Conversely, it is extremely rare among adults, where it shows peculiar biological and clinical features that are still poorly investigated. RMS patients should be referred to a Sarcoma Centre, where the contribution of experienced radiologists plays a relevant role in the diagnostic assessment of the disease, including precise localisation, staging, image-guided biopsy, response evaluation after treatment and follow-up. Read More

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http://dx.doi.org/10.1259/bjr.20200250DOI Listing

Bad neighbours: hypoxia and genomic instability in prostate cancer.

Br J Radiol 2020 Jun 18:20200087. Epub 2020 Jun 18.

Translational Oncogenomics, CRUK Manchester Institute and CRUK Manchester Centre, Manchester, United Kingdom.

Prostate cancer (PCa) is a clinically heterogeneous disease and has poor patient outcome when tumours progress to castration-resistant and metastatic states. Understanding the mechanistic basis for transition to late stage aggressive disease is vital for both assigning patient risk status in the localised setting and also identifying novel treatment strategies to prevent progression. Subregions of intratumoral hypoxia are found in all solid tumours and are associated with many biologic drivers of tumour progression. Read More

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http://dx.doi.org/10.1259/bjr.20200087DOI Listing

Comparison of radiographer interobserver image registration variability using cone beam CT and MR for cervix radiotherapy.

Br J Radiol 2020 Jun 16:20200169. Epub 2020 Jun 16.

Department of Radiotherapy, The Christie NHS Foundation Trust, Manchester, UK.

Objectives: The aim of this study was to assess the consistency of therapy radiographers performing image registration using cone beam computed tomography (CBCT)-CT, magnetic resonance (MR)-CT, and MR-MR image guidance for cervix cancer radiotherapy and to assess that MR-based image guidance is not inferior to CBCT standard practice.

Methods: 10 patients receiving cervix radiation therapy underwent daily CBCT guidance and magnetic resonance (MR) imaging weekly during treatment. Offline registration of each MR image, and corresponding CBCT, to planning CT was performed by five radiographers. Read More

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http://dx.doi.org/10.1259/bjr.20200169DOI Listing

Primary operator radiation dose in the cardiac catheter laboratory.

Br J Radiol 2020 Jun 23:20200018. Epub 2020 Jun 23.

The Prince Charles Hospital, Chermside, Queensland, Australia.

Objectives: Radiation from cardiac angiography procedures is harmful to patients and the staff performing them. This study sought to investigate operator radiation dose for a range of procedures and different operators in order to investigate trends and optimise dose.

Methods: Real-time dosemeters (RTDs) were worn by operators for angiography procedures for 3 years. Read More

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http://dx.doi.org/10.1259/bjr.20200018DOI Listing

Is percutaneous image-guided renal tumour ablation ready for prime time?

Br J Radiol 2020 Jun 22:20200284. Epub 2020 Jun 22.

Interventional Radiology, University Hospital of Strasbourg; 1 place de l'hôpital, 67000, Strasbourg, France.

In the last few decades, thermal ablation (TA) techniques have been increasingly applied to treat small localised renal cell carcinomas. Despite this trend, there is still an underuse of TA compared to surgery and a substantial lack of high-quality evidence derived from large, prospective, randomised controlled trials comparing the long-term oncologic outcomes of TA and surgery. Therefore, in this narrative review, we assess published guidelines and recent literature concerning the diagnosis and management of kidney-confined renal cell carcinoma to understand whether percutaneous image-guided TA is ready to be proposed as a first-line treatment. Read More

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http://dx.doi.org/10.1259/bjr.20200284DOI Listing

Evaluation of genitourinary fistulas in pelvic malignancies with etiopathologic correlation: role of cross sectional imaging in detection and management.

Br J Radiol 2020 Jul 15;93(1111):20200049. Epub 2020 Jun 15.

Department of Surgical Oncology, Basavatarakam Indo American Cancer Hospital & Research Institute, Road No 10, Banjara Hills, Hyderabad, Telangana, India, 500034.

Objective: Genitourinary fistulas in pelvic malignancies are abnormal communications occurring due to either locally advanced tumours invading the surrounding organs or post-therapeutic complications of malignancies. In this article we review and describe the role of cross-sectional imaging findings in the management of genitourinary fistulas in pelvic malignancies.

Methods: A retrospective study, for the period January 2012 to December 2018, was undertaken in patients with pelvic malignancies having genitourinary fistulas. Read More

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http://dx.doi.org/10.1259/bjr.20200049DOI Listing

Diagnostic value and forensic relevance of a novel photorealistic 3D reconstruction technique in post-mortem CT.

Br J Radiol 2020 Jun 18:20200204. Epub 2020 Jun 18.

Department of Diagnostic and Interventional Radiology, University Dusseldorf, Medical Faculty, D-40225, Dusseldorf, Germany.

Objectives: Evaluation of performance and forensic relevance of a novel, photorealistic, 3D reconstruction method (cinematic rendering, (CR)) in comparison with conventional post-mortem CT (PMCT) and volume rendering (VR) technique for visualization of traumatic injuries.

Methods: 112 pathologies (fractures, soft tissue injuries and foreign bodies) from 33 human cadavers undergoing whole body PMCT after traumatic death were retrospectively analyzed. Pathologies were reconstructed with CR and VR techniques. Read More

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http://dx.doi.org/10.1259/bjr.20200204DOI Listing

Left-right breast asymmetry and risk of screen-detected and interval cancers in a large population-based screening population.

Br J Radiol 2020 Jun 22:20200154. Epub 2020 Jun 22.

Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

Objectives: To assess the associations between automated volumetric estimates of mammographic asymmetry and breast cancers detected at the same ("contemporaneous") screen, at subsequent screens, or in between (interval cancers).

Methods: Automated measurements from mammographic images ( = 79,731) were used to estimate absolute asymmetry in breast volume (BV) and dense volume (DV) in a large ethnically diverse population of attendees of a UK breast screening programme. Logistic regression models were fitted to assess asymmetry associations with the odds of a breast cancer detected at contemporaneous screen (767 cases), adjusted for relevant confounders. Read More

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http://dx.doi.org/10.1259/bjr.20200154DOI Listing

CT-guided radiofrequency ablation of osteoid osteoma: established concepts and new ideas.

Br J Radiol 2020 Jun 24:20200266. Epub 2020 Jun 24.

Department of Radiology and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

Osteoid osteoma is a painful benign bone tumour of children and young adults with characteristic clinico-radiological features depending upon the location of the lesion. Intraoperative visualisation of the nidus is difficult and therefore curative surgery is often associated with excessive bone removal, significant perioperative morbidity and potential need of bone grafting procedures. With advancement in cross-sectional imaging and radiofrequency ablation (RFA) technology, CT-guided RFA has emerged as the treatment of choice for the osteoid osteoma. Read More

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http://dx.doi.org/10.1259/bjr.20200266DOI Listing

Survival prediction for oral tongue cancer patients via probabilistic genetic algorithm optimized neural network models.

Br J Radiol 2020 Jun 19:20190825. Epub 2020 Jun 19.

Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA 90095, USA.

Objectives: High throughput pre-treatment imaging features may predict radiation treatment outcome and guide individualized treatment in radiotherapy (RT). Given relatively small patient sample (as compared with high dimensional imaging features), identifying potential prognostic imaging biomarkers is typically challenging. We aimed to develop robust machine learning methods for patient survival prediction using pre-treatment quantitative CT image features for a subgroup of head-and-neck cancer patients. Read More

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http://dx.doi.org/10.1259/bjr.20190825DOI Listing

Non-neoplastic conditions mimicking peritoneal carcinomatosis at CT imaging.

Br J Radiol 2020 Jul 3:20200401. Epub 2020 Jul 3.

Department of Radiology, University of Wisconsin School of Medicine & Public Health, Madison, WI, United States.

The general appearance of peritoneal carcinomatosis at abdominal CT and other cross-sectional imaging modalities consists of varying amounts of peritoneal-based soft tissue implants (mass-forming or infiltrative), peritoneal fluid, and occasionally calcification. However, a wide variety of common and uncommon neoplastic and non-neoplastic conditions can closely mimic peritoneal carcinomatosis at imaging. Neoplastic mimics of peritoneal carcinomatosis include primary peritoneal and sub peritoneal tumors, as well as peritoneal lymphomatosis and sarcomatosis. Read More

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http://dx.doi.org/10.1259/bjr.20200401DOI Listing

Increased visceral adipose tissue in clear cell renal cell carcinoma with and without peritumoral collateral vessels.

Br J Radiol 2020 Jun 16:20200334. Epub 2020 Jun 16.

Unit of Diagnostic Imaging, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21, 00128, Rome, Italy.

Objective: The excessive amount of adipose tissue, mainly visceral, determines adiposopathy. With respect to oncogenesis, visceral adipose tissue (VAT) releases secretes adipokines, proinflammatory citokines and growth factors, considered mediating molecules in the development of obesity-related tumors. In this study, we quantify VAT in male patients with clear cell renal cell carcinoma (ccRCC) subgrouped according to the presence or absence of peritumoral collateral vessels. Read More

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http://dx.doi.org/10.1259/bjr.20200334DOI Listing

Staging of bladder cancer with multiparametric MRI.

Br J Radiol 2020 Jun 9:20200116. Epub 2020 Jun 9.

Department of Diagnostic Radiology, Osaka Medical College, Osaka, Japan.

The distinction of non-muscle-invasive bladder cancer and muscle-invasive bladder cancer is important for the selection of the optimal treatment. Multiparametric MRI (mp-MRI) has been an useful modality for the T staging of bladder cancer, and a systematic evaluation of mp-MRI is needed. The Vesical Imaging Reporting and Data System was designed to standardize the scanning and reporting criteria based on mp-MRI for clinical and research applications. Read More

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http://dx.doi.org/10.1259/bjr.20200116DOI Listing

Radiological features and management of retained needles.

Br J Radiol 2020 Jun 18:20200316. Epub 2020 Jun 18.

Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

The identification of retained needles is essential because of their sharp structure with possible life-threatening complications. However, radiological evaluation could be challenging, especially in case of needles' relatively poor conspicuity and small dimension. This pictorial essay focuses on clinical issues (needle features, retention mechanisms and associated complications) and technical aspects (choice of the best diagnostic modality and technique) that can lead the radiologist to an earlier and proper diagnosis of needle retention in order to provide the best treatment for the patient. Read More

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http://dx.doi.org/10.1259/bjr.20200316DOI Listing

Clinical utility of fat-suppressed 3-dimensional controlled aliasing in parallel imaging results in higher acceleration sampling perfection with application optimized contrast using different flip angle evolutions MRI of the knee in adults.

Br J Radiol 2020 Jun 24:20190725. Epub 2020 Jun 24.

Department of the orthopedic Surgery, Chung-Ang University Hospital, Seoul, Korea.

Objective: To compare htree-dimensional CAIPIRINHA SPACE and two-dimensional turbo spin echo (2D TSE) MRI in the diagnosis of knee pathology in symptomatic adult patients.

Methods: From February to September in 2018, 120 patients who underwent a knee MRI using both 3D CAIPIRINHA SPACE and 2D TSE MRI were enrolled. The signal-to-noise ratios (SNRs) and contrast-to-noise ratio (CNR) of the 2D and 3D MRI were compared using a paired -test. Read More

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http://dx.doi.org/10.1259/bjr.20190725DOI Listing

Impact of dosimetric differences between CT and MRI derived target volumes for external beam cervical cancer radiotherapy.

Br J Radiol 2020 Jun 18:20190564. Epub 2020 Jun 18.

Department of Radiation Oncology, South Western Sydney Local Health District, New South Wales, Australia.

Objectives: The use of MRI is becoming more prevalent in cervical cancer external beam radiotherapy (RT). The aim of this study was to investigate the impact of dosimetric differences between CT and MRI-derived target volumes for cervical cancer external beam RT.

Methods: An automated planning technique for volumetric modulated arc therapy was developed. Read More

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http://dx.doi.org/10.1259/bjr.20190564DOI Listing

A review of the PERFORMS scheme in breast screening.

Br J Radiol 2020 Jun 12:20190908. Epub 2020 Jun 12.

Division of Cancer and Stem Cells, University of Nottingham, Nottingham, UK.

This review details the aetiology of the PERFORMS self-assessment scheme in breast screening, together with its subsequent development, current implementation and future function. The purpose of the scheme is examined and the importance of its continuing role in a changing screening service described, together with current evolution. Read More

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http://dx.doi.org/10.1259/bjr.20190908DOI Listing

Evolution of radiation protection for medical workers.

Br J Radiol 2020 Jun 4:20200282. Epub 2020 Jun 4.

Mayo Clinic, Rochester, MN, USA.

Within a few months of discovery, x-rays were being used worldwide for diagnosis and within a year or two for therapy. It became clear very quickly that while there were immense benefits there were significant associated hazards, not only for the patients, but also for the operators of the equipment. Simple radiation protection measures were implemented within a decade or two and radiation protection for physicians and other operators has continued to evolve over the last century driven by cycles of widening uses, new technologies, realization of previously unidentified effects, development of recommendations and regulations, along with the rise of related societies and professional organizations. Read More

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http://dx.doi.org/10.1259/bjr.20200282DOI Listing

A half-century of innovation in technology-preparing MRI for the 21st century.

Br J Radiol 2020 Jul 15;93(1111):20200113. Epub 2020 Jun 15.

Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands.

MRI developed during the last half-century from a very basic concept to an indispensable non-ionising medical imaging technique that has found broad application in diagnostics, therapy control and far beyond. Due to its excellent soft-tissue contrast and the huge variety of accessible tissue- and physiological-parameters, MRI is often preferred to other existing modalities. In the course of its development, MRI underwent many substantial transformations. Read More

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http://dx.doi.org/10.1259/bjr.20200113DOI Listing

Defining short and prolonged breath-holds.

Br J Radiol 2020 Jul 2;93(1111):20200191. Epub 2020 Jun 2.

Department of Anesthesiology, Amsterdam University Medical Center, location AMC, Meibergdreef, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1259/bjr.20200191DOI Listing

Differential diagnosis of <3 cm renal tumors by ultrasonography: a rapid, quantitative, elastography self-corrected contrast-enhanced ultrasound imaging mode beyond screening.

Br J Radiol 2020 Jun 9:20190974. Epub 2020 Jun 9.

Department of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital & Shanghai Institute of Ultrasound in Medicine, Shanghai, 200233, PR China.

Objectives: To assess the combined diagnostic strategy of contrast-enhanced ultrasound (CEUS) and acoustic radiation force impulse (ARFI) in the precise differential diagnosis of clear cell renal cell carcinoma (CCRCC) and urothelium carcinoma of the renal pelvis (UCRP) with other small renal tumors (SRTs) <3 cm in size.

Methods: The elastography self-corrected CEUS (ESC) mode was established to perform the quantitative differential diagnosis of SRTs (<3 cm). The kidney shear wave velocity (SWV) value recorded by ARFI showed substantial variability in patients with CCRCC (high elasticity value) and UCRP (low elasticity value) compared with other renal masses, thus providing critical self-correction information for the ultrasound differential diagnosis of SRTs. Read More

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http://dx.doi.org/10.1259/bjr.20190974DOI Listing

Comparison of Likert and PI-RADS version 2 MRI scoring systems for the detection of clinically significant prostate cancer.

Br J Radiol 2020 Jun 11:20200298. Epub 2020 Jun 11.

Department of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.

Objective: To compare the performance of Likert and Prostate Imaging-Reporting and Data System (PI-RADS) multiparametric (mp) MRI scoring systems for detecting clinically significant prostate cancer (csPCa).

Methods: 199 biopsy-naïve males undergoing prostate mpMRI were prospectively scored with Likert and PI-RADS systems by four experienced radiologists. A binary cut-off (threshold score ≥3) was used to analyze histological results by three groups: negative, insignificant disease (Gleason 3 + 3; iPCa), and csPCa (Gleason ≥3 +4). Read More

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http://dx.doi.org/10.1259/bjr.20200298DOI Listing

A simple model for calculating relative biological effectiveness of X-rays and gamma radiation in cell survival.

Br J Radiol 2020 Jun 4:20190949. Epub 2020 Jun 4.

Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Objectives: The relative biological effectiveness (RBE) of X-rays and γ radiation increases substantially with decreasing beam energy. This trend affects the efficacy of medical applications of this type of radiation. This study was designed to develop a model based on a survey of experimental data that can reliably predict this trend. Read More

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http://dx.doi.org/10.1259/bjr.20190949DOI Listing

Safety and efficacy of endovascular implantation of a portal vein stent combined with iodine-125 seed-strips followed by transcatheter arterial chemoembolization with sorafenib for the treatment of hepatocellular carcinoma with portal vein tumor thrombosis.

Br J Radiol 2020 Jun 3:20190279. Epub 2020 Jun 3.

Interventional Department, The First Hospital of Lanzhou University, Lanzhou, Gansu, China.

Objective: To assess the safety and efficacy of endovascular implantation of a portal vein stent combined with iodine- seed-strips followed by transcatheter arterial chemoembolization with sorafenib (PVS-I-TACE-S) for the treatment of hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT).

Methods: Between January 2015 and July 2017, 18 patients with PVTT caused by HCC that were treated with PVS-I-TACE-S were reviewed. The technical success, complications, changes in liver function from baseline values due to subsequent endovascular implantation of a portal vein stent combined with iodine- seed-strips (PVS-I), time-to-tumor progression (TTP) and overall survival (OS) were observed. Read More

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http://dx.doi.org/10.1259/bjr.20190279DOI Listing
June 2020
1.533 Impact Factor

Does contrast-enhanced ultrasound (CEUS) play a better role in diagnosis of breast lesions with calcification? A comparison with MRI.

Br J Radiol 2020 Jun 2:20200195. Epub 2020 Jun 2.

Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China.

Objective: To compare the efficacy of contrast-enhanced ultrasound enabled reclassification of Breast Imaging Reporting and Data System (CEUS-BI-RADS) with MRI in the diagnosis of breast lesions with calcification.

Methods: A total of 52 breast lesions with calcification from 51 patients were detected by ultrasound as hyperechoic foci and categorized as BI-RADS 3-5. The 51 patients further underwent CEUS scan and MRI. Read More

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http://dx.doi.org/10.1259/bjr.20200195DOI Listing

Focal nodular marrow hyperplasia: Imaging features of 53 cases.

Br J Radiol 2020 Jun 3:20200206. Epub 2020 Jun 3.

Department of Medical Imaging, Royal National Orthopaedic Hospital, Brockley Hill Stanmore, UK.

Objective: To describe the characteristic imaging features of focal nodular marrow hyperplasia (FNMH).

Methods And Materials: Retrospective review of all patients with a diagnosis of FNMH between January 2007 and September 2019.

Results: The study included 53 patients, 7 males and 46 females with a mean age of 58 years (range 12-95 years). Read More

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http://dx.doi.org/10.1259/bjr.20200206DOI Listing

Undergraduate medical education: a national survey of consultant radiologists.

Authors:
C Chew P J O'Dwyer

Br J Radiol 2020 Jun 2:20200380. Epub 2020 Jun 2.

Emeritus Professor Gastrointestinal Surgery, University of Glasgow, Glasgow, Scotland.

Objective: Rising clinical demand and changes to Radiologists' job plans mean it is becoming ever more difficult for Radiologists to teach medical students.The aim of this study was to assess the current role of Radiologists in undergraduate medical education in Scotland.

Methods: Consultant Radiologists working across all 14 Scottish Health Boards were invited by email to participate in an anonymous short online survey. Read More

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http://dx.doi.org/10.1259/bjr.20200380DOI Listing

BioXmark® liquid fiducial markers for image-guided radiotherapy in muscle invasive bladder cancer: a safety and performance trial.

Br J Radiol 2020 Jul 1;93(1111):20200241. Epub 2020 Jun 1.

Department of radiation oncology, Amsterdam UMC, Amsterdam, The Netherlands.

Objective: This study evaluated the performance of the novel liquid fiducial marker (BioXmark®) in IGRT for bladder cancer.

Methods: 20 patients with muscle invasive bladder cancer were entered in this prospective, single center, Phase I-II study. The novel BioXmark liquid markers were injected around the tumor using a flexible cystoscopy. Read More

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http://dx.doi.org/10.1259/bjr.20200241DOI Listing

Radiobiologically derived biphasic fractionation schemes to overcome the effects of tumour hypoxia.

Br J Radiol 2020 Jun 2:20190250. Epub 2020 Jun 2.

Faculty of Medicine, Imperial College, London, UK.

Objective: As a fractionated course of radiotherapy proceeds tumour shrinkage leads to resolution of hypoxia and the initiation of accelerated proliferation of radioresistant cancer cells with better repair capacity. We hypothesise that, in tumours with significant hypoxia, improved tumour control could be achieved with biphasic fractionation schedules that either use acceleration after 3-4 weeks of conventional radiotherapy or deliver a higher proportional dose towards the end of a course of treatment. We conducted a modelling study based on the concept of biological effective dose (BED) comparing such novel regimens with conventional fractionation. Read More

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http://dx.doi.org/10.1259/bjr.20190250DOI Listing

Patterns of enhancement in the hepatobiliary phase of gadoxetic acid-enhanced MRI.

Br J Radiol 2020 Jun 1:20190989. Epub 2020 Jun 1.

Diagnostic Imaging Department, Monash Health, Melbourne, Australia.

A variety of patterns of enhancement of liver lesions and liver parenchyma is observed in the hepatobiliary phase (HBP) of gadoxetic acid-enhanced MRI. It is becoming increasingly apparent that many lesions may exhibit HBP enhancement. Much of the literature regarding the role of gadoxetic acid-enhanced MRI in characterising liver lesions is dichotomous, focusing on whether lesions are enhancing or non-enhancing in the HBP, rather than examining the patterns of enhancement. Read More

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http://dx.doi.org/10.1259/bjr.20190989DOI Listing

High prevalence of peribronchial focal lesions of airway invasive aspergillosis in hematological cancer patients with prolonged neutropenia.

Br J Radiol 2020 Jun 4:20190693. Epub 2020 Jun 4.

Division of Radiology, Department of interventional and diagnostic radiology, University Hospital of Lausanne, CHUV, Switzerland.

Objective: The aim of this study is to characterize chest CT findings of neutropenic patients with proven/probable invasive pulmonary aspergillosis (IPA).

Methods: Hematological cancer patients admitted to our institution (2007-2017) were retrospectively enrolled if the diagnostic criteria of proven/probable IPA during the neutropenia were met (EORTC/MSG). Galactomannan (GM) was routinely measured in serum and chest CT-scan was routinely performed in case of recurrent/persistent fever. Read More

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http://dx.doi.org/10.1259/bjr.20190693DOI Listing

A comparison of manually populated radiology information system digital radiographic data with electronic dose management systems.

Br J Radiol 2020 Jul 2;93(1111):20200055. Epub 2020 Jun 2.

Medical Physics and Clinical Engineering, Nottingham University Hospitals, Nottingham, NG5 1PB, United Kingdom.

Objective: To assess the accuracy and agreement of radiology information system (RIS) kerma-area product (KAP) data with respect to automatically populated dose management system (DMS) data for digital radiography (DR).

Methods: All adult radiographic examinations over 12 months were exported from the RIS and DMS at three centres. Examinations were matched by unique identifier fields, and grouped by examination type. Read More

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http://dx.doi.org/10.1259/bjr.20200055DOI Listing

Application of monoexponential, biexponential, and stretched-exponential models of diffusion-weighted magnetic resonance imaging in the differential diagnosis of metastases and myeloma in the spine-Univariate and multivariate analysis of related parameters.

Br J Radiol 2020 Jun 11:20190891. Epub 2020 Jun 11.

Department of Radiology, Peking University Third Hospital, Beijing, PR China.

Objective: To explore the value of related parameters in monoexponential, biexponential, and stretched-exponential models of diffusion-weighted imaging (DWI) in differentiating metastases and myeloma in the spine.

Methods: 53 metastases and 16 myeloma patients underwent MRI with 10 b-values (0-1500 s/mm). Parameters of apparent diffusion coefficient (ADC), true diffusion coefficient (D), pseudo-diffusion coefficient (D*), perfusion fraction (f), the distribution diffusion coefficient (DDC), and intravoxel water diffusion heterogeneity (α) from DWI were calculated. Read More

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http://dx.doi.org/10.1259/bjr.20190891DOI Listing
June 2020
1.533 Impact Factor

Emerging strategies to target cancer metabolism and improve radiation therapy outcomes.

Br J Radiol 2020 Jun 23:20200067. Epub 2020 Jun 23.

Department of Radiation Oncology, Wexner Medical Center and Comprehensive Cancer Center The Ohio State University Columbus, OH, USA.

Cancer-specific metabolic changes support the anabolic needs of the rapidly growing tumor, maintain a favorable redox balance, and help cells adapt to microenvironmental stresses like hypoxia and nutrient deprivation. Radiation is extensively applied in a large number of cancer treatment protocols but despite its curative potential, radiation resistance and treatment failures pose a serious problem. Metabolic control of DNA integrity and genomic stability can occur through multiple processes, encompassing cell cycle regulation, nucleotide synthesis, epigenetic regulation of gene activity, and antioxidant defenses. Read More

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http://dx.doi.org/10.1259/bjr.20200067DOI Listing

It is time to think inside the (collimation) box; a quality improvement project to reduce over-scanning in CT scanning of the kidneys, ureters and bladder.

Br J Radiol 2020 May 27:20200068. Epub 2020 May 27.

University of Bristol Medical School, Bristol, United Kingdom.

Objective: The Royal College of Radiologists (RCR) recommend CT of the kidneys, ureters and bladder (CTKUB) as the first-line investigation for renal colic, stating that excess scan length above the upper pole of the highest kidney should not exceed 10% of the total scan length. The project aim was to determine what proportion of CTKUB scans performed at a district general hospital (DGH) were meeting this standard and explore improvement options as necessary.

Methods: A retrospective study was performed on 100 consecutive patients who attended a Radiology Department with renal colic. Read More

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http://dx.doi.org/10.1259/bjr.20200068DOI Listing

Fascia lata attachment at the iliac crest: refining our diagnostic criteria of injury on magnetic resonance imaging.

Br J Radiol 2020 Jul 27;93(1111):20200187. Epub 2020 May 27.

Department of Radiology, Northwestern University, Chicago, Illinois, United States.

Objective: The objective of this study was to determine the prevalence and spectrum of pathology of the fascia lata attachment at the iliac crest (FLAIC) on MRI in asymptomatic patients in order to refine our diagnostic criteria for clinically relevant FLAIC injury.

Methods And Material: Two readers retrospectively evaluated the FLAIC on each side on coronal large field-of-view short tau inversion recovery images on 100 musculoskeletal pelvic MRI exams performed in patients without hip pain (total = 200). Pathology of the FLAIC was graded using a 3-point Likert scale and discrepancies were resolved by consensus. Read More

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http://dx.doi.org/10.1259/bjr.20200187DOI Listing

Chest CT-based differential diagnosis of 28 patients with suspected corona virus disease 2019 (COVID-19).

Br J Radiol 2020 Jun 2:20200243. Epub 2020 Jun 2.

Department of Infectious Disease, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Objectives: The chest CT findings that can distinguish patients with corona virus disease 2019 (COVID-19) from those with clinically suspected COVID-19 but subsequently found to be COVID-19 negative have not previously been described in detail. The purpose of this study was to determine the distinctions among patients with COVID-19 by comparing the imaging findings of patients with suspected confirmed COVID-19 and those of patients initially suspected to have COVID-19 who were ultimately negative for the disease.

Methods: 28 isolated suspected in-patients with COVID-19 were enrolled in this retrospective study from January 22, 2020 to February 6, 2020. Read More

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http://dx.doi.org/10.1259/bjr.20200243DOI Listing

Minimizing contrast media dose in CT pulmonary angiography with high-pitch technique.

Br J Radiol 2020 Jul 21;93(1111):20190995. Epub 2020 May 21.

Department of Radiology, Faculty of Medicine and Health, Örebro University, S-70182 Örebro, Sweden.

Objectives: To perform CT pulmonary angiography (CTPA) using a minimal amount of iodinated contrast media.

Methods: 47 patients (25 females) with mean age 69 years (range 41-82 years) referred for contrast-enhanced chest CT were prospectively included in this Phase IV clinical drug trial. All participants underwent a study specific CTPA in addition to the chest CT. Read More

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http://dx.doi.org/10.1259/bjr.20190995DOI Listing

The impact of restricted length of treatment field and anthropometric factors on selection of head and neck cancer patients for treatment on the MR-Linac.

Br J Radiol 2020 Jul 21;93(1111):20200023. Epub 2020 May 21.

The Institute of Cancer Research and Royal Marsden NHS Trust, Head and Neck Radiotherapy and Imaging, Sutton, United Kingdom.

Objective: This study investigates the impact of a restricted craniocaudal (CC) field length of <20 cm on the selection of head and neck cancer (HNC) patients who can be treated on the MR-Linac using a single isocentre technique. We also assess the effects of anthropometric factors and the neck position on the CC field length.

Methods: 110 HNC patients who underwent radical primary or adjuvant radiotherapy were retrospectively analysed. Read More

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http://dx.doi.org/10.1259/bjr.20200023DOI Listing

Comparison of quantity and quality of muscle as clinical prognostic markers in patients undergoing carotid endarterectomy.

Br J Radiol 2020 Jul 27;93(1111):20200136. Epub 2020 May 27.

Leeds Vascular Institute, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Great George Street, Leeds, LS1 3EX, United Kingdom.

Objective: The measurement of muscle area is routinely utilised in determining sarcopaenia in clinical research. However, this simple measure fails to factor in age-related morphometric changes in muscle quality such as myosteatosis. The aims of this study were to: firstly investigate the relationship between the masseter area (quantity) and density (quality), and secondly compare the prognostic clinical relevance of each parameter. Read More

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http://dx.doi.org/10.1259/bjr.20200136DOI Listing
July 2020
1.533 Impact Factor

Aggressive pelvic angiomyxoma and its mimics: can imaging be the guiding light?

Br J Radiol 2020 Jul 21;93(1111):20200255. Epub 2020 May 21.

Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.

Objective: To evaluate the imaging characteristics of aggressive angiomyxoma (AA) and identify features which would help to differentiate it from similar appearing lesions.

Methods: A retrospective review of departmental records was done and cases where AA was suspected on CT or MRI were included. With histopathology as gold-standard, the cases were grouped into AA or mimics and differentiating features were identified on USG, CT and MRI. Read More

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http://dx.doi.org/10.1259/bjr.20200255DOI Listing
July 2020
1.533 Impact Factor