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    16080 results match your criteria British Journal of Radiology[Journal]

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    Effects of dose-escalated radiotherapy in combination with long-term androgen deprivation on prostate cancer.
    Br J Radiol 2017 Nov 22:20170431. Epub 2017 Nov 22.
    1 Department of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
    Objective: We aimed to examine the effects of a dose escalation for prostate cancer patients receiving long-term androgen deprivation therapy (ADT).

    Methods: A retrospective analysis of 605 patients treated with radiotherapy and long-term ADT (National Comprehensive Cancer Network criteria-defined intermediate-risk; minimum 10 months, high-risk and very-high-risk; minimum 20 months) was performed. The median ADT time was 31 months. Read More

    Primary constrained TIPS for treating refractory ascites or variceal bleeding secondary to hepatic cirrhosis.
    Br J Radiol 2017 Nov 22:20170409. Epub 2017 Nov 22.
    2 Rush University Medical Center, Chicago, IL, USA.
    Purpose: To report an initial experience using a primary constrained TIPS technique for treating cirrhotic patients with refractory ascites or variceal bleeding.

    Methods: All patients undergoing primary constrained (n=9) and conventional (n=18) TIPS between July 2014 and June 2016 were retrospectively reviewed. Pre-procedure demographics, Child-Pugh (CP), MELD, and technical variables were recorded. Read More

    Application of diffusion tensor imaging in quantitatively monitoring chronic constriction injury of rabbit sciatic nerves: correlation with histological and functional changes.
    Br J Radiol 2017 Nov 22:20170414. Epub 2017 Nov 22.
    1 Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
    Objective: To investigate the potential of diffusion tensor imaging (DTI) in quantitatively monitoring chronic constriction injuries (CCI) of sciatic nerves and to analyze the association of DTI parameters with nerve histology and limb function.

    Methods: CCI was created on sciatic nerves in the right hind legs of 20 rabbits with the left as control. DTI parameters -- fractional anisotropy (FA), apparent diffusion coefficient (ADC), axial diffusivity (AD) and radial diffusivity (RD) -- and limb function were longitudinally evaluated. Read More

    Dosimetric impact of gastrointestinal air column in radiation treatment of pancreatic cancer.
    Br J Radiol 2017 Nov 22:20170512. Epub 2017 Nov 22.
    4 Department of Radiation Oncology, New York University Langone Medical Center, New York, NY, USA.
    Objective: Dosimetric evaluation of air column in gastro-intestinal (GI) structures in IMRT of pancreatic cancer.

    Methods: Nine sequential patients were retrospectively chosen for dosimetric analysis of air column in the GI apparatus in pancreatic cancer using cone beam CT (CBCT). The 4DCT was used for target and organs at risk (OARs) and non-coplanar IMRT was used for treatment. Read More

    Imaging of iatrogenic esophageal injuries using optimized CT esophageal leak protocol: pearls and pitfalls.
    Br J Radiol 2017 Nov 22:20170629. Epub 2017 Nov 22.
    4 Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
    Iatrogenic injury to the esophagus is a serious complication which is increasingly seen in clinical practice secondary to expansion and greater acceptability of surgical and endoscopic esophageal procedures. Morbidity and mortality following such injury is high. This is mostly due to an inflammatory response to gastric contents in the mediastinum, and the negative intra-thoracic pressures that may further draw out esophageal contents into the mediastinum leading to mediastinitis. Read More

    Initial observations of intra- and inter- fractional motion variation in MR guided lung SBRT.
    Br J Radiol 2017 Nov 22:20170522. Epub 2017 Nov 22.
    2 Department of Radiation Oncology, University of California, Los Angeles, CA, USA.
    Objective: To evaluate variations in intra- and inter-fractional tumor motion, and the effect on ITV contour accuracy, using deformable image registration of real-time 2D-sagital cine-mode MRI acquired during lung SBRT treatments.

    Methods: Five lung tumor patients underwent free breathing SBRT treatments on the ViewRay system, with dose prescribed to a planning target volume (PTV; defined as a 3-6 mm expansion of the 4DCT-ITV). Sagittal slice cine-MR images (3. Read More

    Towards enhanced PET quantification in clinical oncology.
    Br J Radiol 2017 Nov 22:20170508. Epub 2017 Nov 22.
    5 5Translational and Molecular Imaging Institute, Department of Radiology, ICAHN School of Medicine at Mount Sinai, Newyork, NY, USA.
    Positron emission tomography (PET) has, since its inception, established itself as the imaging modality of choice for the in vivo quantitative assessment of molecular targets in a wide range of biochemical processes underlying tumour physiology. PET image quantification enables to ascertain a direct link between the time-varying activity concentration in organs/tissues and the fundamental parameters portraying the biological processes at the cellular level being assessed. However, the quantitative potential of PET may be affected by a number of factors related to physical effects, hardware and software system specifications, tracer kinetics, motion, scan protocol design and limitations in current image-derived PET metrics. Read More

    Accuracy of the raw-data based effective atomic numbers and monochromatic CT numbers for contrast medium with a dual-energy CT technique.
    Br J Radiol 2017 Nov 21:20170524. Epub 2017 Nov 21.
    4 Department of Radiation Oncology, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
    Objective: The aim of this study is to evaluate the accuracies of the raw-data based effective atomic number (Zeff) and monochromatic CT numbers for varying contrast material iodine concentration obtained using dual-energy CT.

    Methods: We used a tissue characterization phantom and different concentrations of iodinated contrast medium. A comparison between the calculated values of Zeff and that provided by the manufacturer was performed. Read More

    Imaging assessment of acute ischaemic stroke - a review of radiological methods.
    Br J Radiol 2017 Nov 16:20170573. Epub 2017 Nov 16.
    Neuroradiology Consultant, Hull Royal Infirmary, Hull, UK.
    Acute ischaemic stroke is the second largest cause of death worldwide and a cause of major physical and psychological morbidity. Current evidence based treatment includes intravenous thrombolysis (IVT) and mechanical thrombectomy (MT), both requiring careful patient selection and to be administered as quickly as possible within a limited time window from symptom onset. Imaging plays a crucial role identifying patients who may benefit from MT or IVT whilst excluding those that maybe harmed. Read More

    Correlation between obesity and fat-infiltrated axillary lymph nodes visualized on mammography.
    Br J Radiol 2017 Nov 16:20170110. Epub 2017 Nov 16.
    3 Department of Biomedical Data Science, The Dartmouth Institute for Health Policy and Clinical Practice, One Medical Center Dr., Lebanon, NH, USA.
    Objective: Using screening mammography, this study investigated the association between obesity and axillary lymph node (LN) size and morphology.

    Methods: We conducted a retrospective review of 188 women who underwent screening mammography at an academic medical center. Length and width of the LN and hilum were measured in the largest, mammographically visible axillary node. Read More

    Demand for CT scans increases during transition from paediatric to adult care: An observational study from 2009 to 2015.
    Br J Radiol 2017 Nov 16:20170467. Epub 2017 Nov 16.
    2 Division of Epidemiology and Public Health, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham, UK.
    Objective: Avoiding unnecessary radiation exposure is a clinical priority in children and young adults. We aimed to explore demand for CT scans in a busy general hospital with particular interest in the period of transition from paediatric to adult medical care.

    Methods: We used an observational epidemiological study based in a teaching hospital. Read More

    Use of patient outcome endpoints to identify the best functional CT imaging parameters in metastatic renal cell carcinoma patients.
    Br J Radiol 2017 Nov 16. Epub 2017 Nov 16.
    1 Department of Radiology, Aarhus University Hospital, Aarhus, Denmark.
    Objective: To use the patient outcome endpoints overall survival and progression-free survival to evaluate functional parameters derived from dynamic contrast-enhanced computed tomography (DCE-CT).

    Methods: 69 patients with metastatic renal cell carcinoma (mRCC) had DCE-CT scans at baseline and after 5 and 10 weeks of treatment. Blood volume, blood flow and standardized perfusion values were calculated using deconvolution (BVdeconv, BFdeconv and SPVdeconv), blood flow and standardized perfusion values using maximum slope (BFmax and SPVmax), and blood volume and permeability surface area product using the Patlak model (BVpatlak and PS). Read More

    Shear-Wave Elastography quantitative assessment of the male breast: added value to distinguish benign and malignant palpable masses.
    Br J Radiol 2017 Nov 16:20170676. Epub 2017 Nov 16.
    1 Department of Radiology, Institut Bergonié, comprehensive cancer center, Bordeaux, France.
    Objective: To evaluate the ability of shear-wave elastography (SWE) to distinguish between benign and malignant palpable masses of the adult male breast.

    Methods: Clinical examination, mammography, B-mode and Doppler ultrasound (US) findings and SWE quantitative parameters were compared in 50 benign lesions (including 40 gynecomastias) and 15 malignant lesions (invasive ductal carcinomas) from 65 patients who were consecutively addressed for specialized advice at our comprehensive cancer center. Mean elasticity (El mean), maximum elasticity (El max), El mean of the surrounding fatty tissue and lesion to fat ratio (El ratio) were reported for each patient. Read More

    Intravoxel incoherent motion diffusion-weighted mr imaging for differentiation of benign and malignant musculoskeletal tumors at 3 T.
    Br J Radiol 2017 Nov 16:20170636. Epub 2017 Nov 16.
    4 Department of Orthopedic Surgery, Seoul St. Mary's Hospital, School of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
    Objective: To evaluate the intravoxel incoherent motion (IVIM) diffusion-weighted (DW) magnetic resonance imaging (MRI) for differentiating between benign and malignant musculoskeletal tumors at 3 T.

    Methods: Sixty-five patients with treatment-naïve musculoskeletal tumors (47 malignant and 23 benign lesions) who underwent 3 T MRI including IVIM DW imaging were included. IVIM-derived parameters included pure diffusion coefficient (D), perfusion related incoherent microcirculation (D*, pseudodiffusion coefficient), and perfusion fraction (f). Read More

    The value of superb microvascular imaging in differentiating benign renal mass from malignant renal tumor: a retrospective study.
    Br J Radiol 2017 Nov 10:20170601. Epub 2017 Nov 10.
    Department of Ultrasound Diagnosis and Treatment, Tianjin Medical University Cancer Institute and Hospital, Tianjin Shi, China.
    Objective: This study is to evaluate the value of SMI in assessing renal tumor vascularity and in differentiating benign from malignant renal tumors.

    Methods: Patients with pathologically-confirmed renal mass who underwent CDFI and SMI examination between October 2016 and March 2017 were retrospectively analyzed. Patients were classified into benign renal mass group and malignant tumor group according to their pathological results. Read More

    A useful method for assessing differences of compensatory hypertrophy in the contralateral kidney before and after radical nephrectomy in patients with renal cell carcinoma: Ellipsoid formula on computed tomography.
    Br J Radiol 2017 Nov 10:20170425. Epub 2017 Nov 10.
    2 Department of Urology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
    Objective: To investigate the usefulness of the ellipsoid formula for assessing compensatory hypertrophy of the contralateral kidney on preoperative and postoperative CT in renal cell carcinoma(RCC) patients.

    Methods: We retrospectively identified 389 patients who had radical nephrectomy for RCC between 2011 and 2015. Contrast-enhanced CT was performed within three months preoperative and at 1 year postoperative. Read More

    A review of mammographic positioning image quality criteria for the craniocaudal projection.
    Br J Radiol 2017 Nov 10:20170611. Epub 2017 Nov 10.
    1 Discipline of Medical Radiation Science, Faculty of Health Science and Brain and Mind Centre, University of Sydney, Sydney, NSW, Australia.
    Detection of breast cancer is reliant on optimal breast positioning and the production of quality images. Two projections, the mediolateral (MLO) and craniocaudal (CC), are routinely performed. Determination of successful positioning and inclusion of all breast tissue is achieved through meeting stated image quality criteria. Read More

    Submillisievert chest dual energy computed tomography: a pilot study.
    Br J Radiol 2017 Nov 10:20170735. Epub 2017 Nov 10.
    Division of Thoracic Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
    Objective: To assess if diagnostic dual energy CT of the chest can be achieved at submillisievert doses (sub-mSv).

    Methods: Our IRB-approved prospective study included 20 patients who were scanned on dual-source MDCT. All patients gave written informed consent for acquisition of additional image series at reduced radiation dose on a dual-source MDCT (80/140kV) within 10 seconds after the standard of care acquisition. Read More

    Enhanced pre-operative axillary staging using intradermal microbubbles and contrast-enhanced ultrasound to detect and biopsy sentinel lymph nodes in breast cancer: A potential replacement for axillary surgery.
    Br J Radiol 2017 Nov 10:20170626. Epub 2017 Nov 10.
    8 Breast Unit, Addenbrooke's Treatment Centre, Keith Day Rd, Cambridge, UK.
    Objective: To compare the experience of 4 UK Centres in the use of intradermal microbubbles and contrast enhanced ultrasound (CEUS) to pre-operatively identify and biopsy sentinel lymph nodes (SLN) in patients with breast cancer.

    Methods: In all centres, breast cancer patients had a microbubble/ CEUS SLN core biopsy prior to axillary surgery and patients in Centres 1 and 2 had a normal grey-scale axillary ultrasound. Data was collected between 2010 and 2016; 1361 from Centre 1 (prospective, sequential), 376 from Centre 2 (retrospective, sequential), 122 from Centre 3 (retrospective, selected) and 48 from Centre 4 (prospective, selected). Read More

    ABO blood group related venous thrombosis risk in patients with peripherally inserted central catheters.
    Br J Radiol 2017 Nov 10:20170560. Epub 2017 Nov 10.
    6 Sansom Institute for Health Research, University of South Australia, Adelaide, SA, Australia.
    Objective: To investigate the association between ABO blood group and venous thrombosis (VT) risk in patients with peripherally inserted central catheters (PICC).

    Methods: Single centre retrospective cohort study. A cohort of patients who underwent PICC insertion from September 2010 to August 2014 were followed up for symptomatic VT presentations diagnosed by ultrasound. Read More

    (18)FDG-PET/CT is useful in the follow-up of surgically treated patients with esophageal adenocarcinoma.
    Br J Radiol 2017 Nov 10:20170341. Epub 2017 Nov 10.
    1 The University of Texas, M.D. Anderson Cancer Center. 1515 Holcombe Blvd., Houston, TX, USA.
    Purpose: The purpose of this study was to evaluate FDG- PET/CT's performance in the follow-up of patients with surgically treated esophageal adenocarcinoma.

    Material And Methods: The follow-up FDG-PET/CT scans of 162 consecutive patients with surgically treated esophageal adenocarcinoma were retrospectively reviewed. Histopathological and/or imaging examinations confirmed recurrent disease. Read More

    Benign and malignant enlarged chest nodes staging by diffusion weighted MRI: an alternative to mediastinoscopy?
    Br J Radiol 2017 Nov 10:20160919. Epub 2017 Nov 10.
    1 CNRS, CREATIS UMR 5220, Université Claude Bernard Lyon 1, Inserm U1206, INSA, Lyon, France.
    Objective: To evaluate the accuracy of diffusion weighted MRI with background suppression (DWIBS) in differentiating between malignant and benign mediastinal lymph-nodes.

    Methods: Consecutive patients with enlarged mediastinal lymph-nodes underwent MRI DWIBS within 10 days prior to mediastinoscopy. Relative contrast ratios (RCR) were computed on b800 and apparent diffusion coefficient (ADC) maps by dividing the node signal with the chest muscle signal, using manually drawn regions of interest (ROIs) by radiologists, blinded to pathology. Read More

    Automated retrieval of radiotherapy data for clinical trials, audit and research.
    Br J Radiol 2017 Nov 10:20170651. Epub 2017 Nov 10.
    1 Department of Medical Physics & Clinical Engineering, Cambridge University Hospitals, Cambridge, UK.
    Objective: To enable fast and customisable automated collection of radiotherapy data from tomotherapy storage.

    Methods: Human-readable data maps (TagMaps) were created to generate DICOM-RT data from tomotherapy archives, and provided access to "hidden" information comprising delivery sinograms, positional corrections and adaptive-RT doses.

    Results: 797 datasets totalling 25,000 scans were batch-exported in 31. Read More

    Screening for Lung cancer using sub-millisievert chest CT with iterative reconstruction algorithm: image quality and nodule detectability.
    Br J Radiol 2017 Nov 9:20170658. Epub 2017 Nov 9.
    1 Department of Radiology, Peking University People's Hospital, Beijing Shi, China.
    Objective: To investigate the image quality and nodules detectability using ultra-low dose (ULD) protocol with iterative model reconstruction (IMR) algorithm when compared to routine low dose (LD) chest CT in lung cancer screening.

    Methods: Chest CT scans were acquired using a 256-slice scanner for 300 subjects. The scan protocol for ULD group was 120kVp/17mAs while the LD group was 120kVp/30mAs. Read More

    Comparison of MRI visualisation between linearly placed iron-containing and non-iron-containing fiducial markers for prostate radiotherapy.
    Br J Radiol 2017 Nov 9:20170612. Epub 2017 Nov 9.
    4 Department of Radiology, Gifu University School of Medicine, Gifu, Japan.
    Objective: Visualising the gold marker (GM) in CT and MRI is critical, especially for registration in high-precision radiotherapy. GM sizes vary. Large markers are easily visualised in MRI. Read More

    Rectal cancer confined to the bowel wall: the role of 3 Tesla phased-array MR imaging in T categorization.
    Br J Radiol 2017 Nov 21:20170581. Epub 2017 Nov 21.
    4 Department of Pathology,Ankara University, Professor, School of Medicine , Ankara University, Professor, School of Medicine , Ankara , Turkey.
    Objective: To determine the diagnostic value of 3 Tesla MR imaging in detection of mucosal (Tis), submucosal (T1) and muscularis propria (T2) invasion in patients with early rectal cancer.

    Methods: A total of 50 consecutive patients who underwent 3 Tesla MR imaging and curative-intent intervention for MRI-staged Tis/T1/T2 rectal cancer from March 2012 to December 2016 were included. The radiological T category of each rectal tumour was compared retrospectively with histopathological results assessed according to the tumor, node, metastasis (TNM) classification. Read More

    Minimally invasive pancreatic necrosectomy; a technical pictorial review.
    Br J Radiol 2017 Nov 13:20170435. Epub 2017 Nov 13.
    3 Department of Interventional Radiology, Cambridge University Hospitals , Cambridge , UK.
    Necrotizing pancreatitis is the most severe form of acute pancreatitis, which is associated with significant mortality and morbidity. Open necrosectomy has been one of the treatment modalities; however, it has been associated with high mortality rates and alternative minimally invasive procedures such as minimal invasive pancreatic necrosectomy (MIPN) were developed to improve on the outcomes. While current clinical evidence on MIPN showed significant advantages in terms of incidence of multiple organ failure, incisional hernias and new-onset diabetes there were no differences in terms of mortality rate. Read More

    Investigating the minimum scan parameters required to generate free-breathing motion artefact-free fast-helical CT.
    Br J Radiol 2017 Nov 21:20170597. Epub 2017 Nov 21.
    3 Department of Radiation Oncology, University of California, Los Angeles , University of California, Los Angeles , California, CA , USA.
    Objective: A recently proposed "5DCT" protocol uses deformable registration of free-breathing fast-helical CT scans to generate a breathing motion model. In order to allow accurate registration, free-breathing images are required to be free of doubling-artefacts, which arise when tissue motion is greater than scan speed.

    Methods: Using a unique set of digital phantoms based on patient data and verified with a motion phantom, this work identifies the minimum scanner parameters required to successfully generate free-breathing artefact-free fast-helical scans. Read More

    Interrater reliability and radiation dosage of oblique coronal computed tomography for sacroiliitis in comparison with axial computed tomography.
    Br J Radiol 2017 Nov 3:20150700. Epub 2017 Nov 3.
    3 Department of Rheumatology , The First Affiliated Hospital of Chinese PLA General Hospital , Beijing, China.
    Objective: Sacroiliitis, a prerequisite to the diagnosis of ankylosing spondylitis, can be ascertained by CT when MRI is not available. Oblique coronal CT is an increasingly popular approach when examining sacroiliitis. The goal of this study was to understand how oblique coronal CT compared with axial CT scanning in terms of raters' concordance when diagnosing sacroiliitis. Read More

    Diagnostic accuracy of (18)F-FDG PET/CT for detection of peritoneal carcinomatosis; a systematic review and meta-analysis.
    Br J Radiol 2017 Nov 21:20170519. Epub 2017 Nov 21.
    3 Department of Nuclear Medicine, Kyungpook National University Medical Center and School of Medicine , Kyungpook National University Medical Center and School of Medicine , Daegu , Republic of Korea.
    Objective: The current review aimed to investigate the performance of the diagnostic accuracy of (18)F- fludeoxyglucose positron emission tomography/CT (PET/CT) in detecting peritoneal carcinomatosis (PC) through a systematic review and meta-analysis.

    Methods: The MEDLINE via PubMed and EMBASE from the earliest available date of indexing to 31 March 2017, were searched for studies evaluating the diagnostic performance of (18)F-FDG PET/CT in detecting PC. We evaluated the pooled sensitivities and specificities across included studies, calculated positive and negative likelihood ratios (LR+ and LR-), and plotted summary receiver operating characteristic curves. Read More

    Diagnostic performance and useful findings of ultrasound re-evaluation for patients with equivocal CT features of acute appendicitis.
    Br J Radiol 2017 Nov 9:20170529. Epub 2017 Nov 9.
    3 Department of Nuclear Medicine , Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine , Seoul, Republic of Korea.
    Objective: To evaluate the diagnostic performance of ultrasound and to determine which ultrasound findings are useful to differentiate appendicitis from non-appendicitis in patients who underwent ultrasound re-evaluation owing to equivocal CT features of acute appendicitis.

    Methods: 62 patients who underwent CT examinations for suspected appendicitis followed by ultrasound re-evaluation owing to equivocal CT findings were included. Equivocal CT findings were considered based on the presence of only one or two findings among the CT criteria, and ultrasound re-evaluation was done based on a predefined structured report form. Read More

    SPECT/CT arthrography.
    Br J Radiol 2017 Nov 16:20170635. Epub 2017 Nov 16.
    1 Nuclear Medicine and Radiology, Cantonal Hospital Lucerne, Lucerne, Switzerland.
    Single photon emission CT (SPECT)/CT arthrography, the combination of CT arthrography and late phase bone SPECT/CT, has been developed in 2011 and so far used in knee, ankle and wrist joints. SPECT/CT offers functional information about increased bone turnover in combination with morphological details. Compared with SPECT/CT alone, additional intra-articular contrast enables the assessment of cartilage, menisci, ligaments and loose bodies. Read More

    Image once, print thrice? Three-dimensional printing of replacement parts.
    Br J Radiol 2017 Nov 1:20170374. Epub 2017 Nov 1.
    4 University of Arizona Health Sciences Center, Southern Arizona Limb Salvage Alliance, Tucson, AZ, USA.
    Objective: The last 20 years has seen an exponential increase in 3D printing as it pertains to the medical industry and more specifically surgery. Previous reviews in this domain have chosen to focus on applications within a specific field. To our knowledge none have evaluated the broad applications of patient-specific or Digital Imaging and Communications in Medicine (DICOM) derived applications of this technology. Read More

    Effect of age-dependent bone electron density on the calculated dose distribution from kilovoltage and megavoltage photon and electron radiotherapy in paediatric MRI-only treatment planning.
    Br J Radiol 2017 Nov 9:20170511. Epub 2017 Nov 9.
    2 Radiation Research Center, School of Mechanical Engineering, Shiraz University, Shiraz, Iran.
    Objective: MRI-only treatment planning (TP) can be advantageous in paediatric radiotherapy. However, electron density extraction is necessary for dose calculation. Normally, after bone segmentation, a bulk density is assigned. Read More

    Pilot study: safety and effectiveness of simple ultrasound-guided high-intensity focused ultrasound ablating uterine leiomyoma with a diameter greater than 10 cm.
    Br J Radiol 2017 Nov 21:20160950. Epub 2017 Nov 21.
    1 Department of Gynecology and Gynecology and Obstetrics,The First Affiliated Hospital of Xinxiang Medical University , The First Affiliated Hospital of Xinxiang Medical University , Weihui, Henan , PR China.
    Objective: The study aimed to prospectively investigate whether uterine leiomyoma greater than 10 cm in diameter could be treated with simple ultrasound-guided high-intensity focused ultrasound (USgHIFU) in one-time treatment.

    Methods: A total of 36 patients with 36 symptomatic uterine leiomyoma greater than 10 cm in diameter who underwent simple USgHIFU treatment alone were analysed. Enhanced MRI was performed before and after HIFU treatment, and all patients had follow-up for 6 months after treatment. Read More

    Contrast enhancement in abdominal computed tomography: influence of photon energy of different scanners.
    Br J Radiol 2017 Nov 6:20170285. Epub 2017 Nov 6.
    1 Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University , Kumamoto , Japan.
    Objective: Different CT scanners have different X-ray spectra and photon energies indicating that contrast enhancement vary among scanners. However, this issue has not been fully validated; therefore, we performed phantom and clinical studies to assess this difference.

    Methods: Two scanners were used: scanner-A and scanner-B. Read More

    UK Quantitative WB-DWI Technical Workgroup: consensus meeting recommendations on optimisation, quality control, processing and analysis of quantitative whole-body diffusion weighted imaging for cancer.
    Br J Radiol 2017 Oct 27:20170577. Epub 2017 Oct 27.
    27 Centre for Medical Imaging, University College Hospital, London, UK.
    Introduction: Application of whole body diffusion weighted MRI (WB-DWI) for oncology are rapidly increasing within both research and routine clinical domains. However, WB-DWI as a quantitative imaging biomarker (QIB) has significantly slower adoption. To date challenges relating to accuracy and reproducibility, essential criteria for a good QIB, have limited widespread clinical translation. Read More

    Radioactive seed localization compared with wire-guided localization of non-palpable breast carcinoma in breast conservation surgery- the first experience in the United Kingdom.
    Br J Radiol 2017 Nov 16:20170268. Epub 2017 Nov 16.
    2 Department of Breast Surgery,Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust , Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust , Newcastle Upon Tyne , UK.
    Objective: In the UK, guidewires have traditionally been used for localization of non-palpable breast lesions in patients undergoing breast conservation surgery (BCS). Radioactive seed localization (RSL) using Iodine-125 seeds is an alternative localization method and involves inserting a titanium capsule, containing radioactive Iodine-125, into the breast lesion. We aim to demonstrate feasibility of RSL compared with guidewire-localization (GWL) for BCS in the UK. Read More

    Predicting poor outcome from simple ankle injuries: a prospective cohort study.
    Br J Radiol 2017 Nov 9:20170213. Epub 2017 Nov 9.
    1 St Luke's Radiology , Oxford , UK.
    Background: Sprained ankles are common and when there are no signs or evidence of a fracture, conventional management is conservative. At present, there are no clinical markers to identify those that may develop persisting instability and disability that would require rehabilitation or surgery.

    Objectives: To investigate the nature and extent of soft tissue ankle injuries, and to consider whether the anatomical severity of injury can predict functional outcome. Read More

    Cost-effectiveness of magnetic resonance carotid plaque imaging for primary stroke prevention in Canada.
    Br J Radiol 2017 Nov 21:20170518. Epub 2017 Nov 21.
    1 Department of Medical Imaging,University of Toronto , University of Toronto , Toronto, ON , Canada.
    Objective: Magnetic resonance of the carotid arteries provides important insight into plaque composition and vulnerability in addition to the traditional measure of stenosis. The purpose of this study was to evaluate the cost-effectiveness of MR imaging as a first-line modality to assess carotid disease and guide management for high-risk patients with <50% stenosis.

    Methods: Using TreeAge Pro, a cost-effectiveness simulation was conducted comparing two strategies: (a) standard of care first-line carotid duplex ultrasound (DUS) with regular follow-up, vs (b) first-line MR assessment of stenosis and intraplaque haemorrhage (MRIPH) in which patients with IPH received annual DUS surveillance and immediate carotid endarterectomy in case of plaque progression. Read More

    Depiction of lower limb venous anatomy in patients undergoing interventional deep venous reconstruction-the role of balanced steady state free precession MRI.
    Br J Radiol 2017 Nov 3:20170005. Epub 2017 Nov 3.
    2 Department of Radiology, Guy's & St Thomas' NHS Foundation Trust , London , UK.
    Objectives: This study evaluates the use of balanced steady-state free precession MRI (bSSFP-MRI) in the diagnostic work-up of patients undergoing interventional deep venous reconstruction (I-DVR). Intravenous digital subtraction angiography (IVDSA) was used as the gold-standard for comparison to assess disease extent and severity.

    Methods: A retrospective comparison of bSSFP-MRI to IVDSA was performed in all patients undergoing both examinations for treatment planning prior to I-DVR. Read More

    Assessment of noise reduction potential and image quality improvement of a new generation adaptive statistical iterative reconstruction (ASIR-V) in chest CT.
    Br J Radiol 2017 Nov 16:20170521. Epub 2017 Nov 16.
    1 College of Medical Technology, Shaanxi University of Chinese Medicine, Xianyang, China.
    Objective: To evaluate the image quality improvement and noise reduction in routine dose, non-enhanced chest CT imaging by using a new generation adaptive statistical iterative reconstruction (ASIR-V) in comparison with ASIR algorithm.

    Methods: 30 patients who underwent routine dose, non-enhanced chest CT using GE Discovery CT750HU (GE Healthcare, Waukesha, WI) were included. The scan parameters included tube voltage of 120 kVp, automatic tube current modulation to obtain a noise index of 14HU, rotation speed of 0. Read More

    Flat epithelial atypia: conservative management of patients without residual microcalcifications post-vacuum-assisted breast biopsy.
    Br J Radiol 2017 Nov 9:20170484. Epub 2017 Nov 9.
    3 Department of Radiology, Policlinico San Martino , Genoa , Italy.
    Objective: To determine the malignancy rate (defined in this study as stability or absence of malignancy developed on close imaging follow-up post-biopsy) of conservative management in patients with a vacuum-assisted breast biopsy (VAB) diagnosis of flat epithelial atypia (FEA), performed on single group of microcalcifications, completely removed during procedure.

    Methods: This is a retrospective, monocentric, observational study, approved by IRB. Inclusion criteria were: VAB performed on a single group of microcalcifications; the absence of residual calcifications post-VAB; diagnosis of isolated FEA as the most advanced proliferative lesion; radiological follow-up at least of 12 months. Read More

    Dual-region-of-interest bolus-tracking technique for coronary computed tomographic angiography on a 320-row scanner: reduction in the interpatient variability of arterial contrast enhancement.
    Br J Radiol 2017 Nov 8:20170541. Epub 2017 Nov 8.
    2 Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
    Objective: We compared the effect of a dual-region-of-interest (ROI) bolus-tracking technique on interpatient variability of arterial contrast enhancement with that of the conventional bolus-tracking technique in coronary computed tomographic angiography (CTA) on a 320-row scanner.

    Methods: This study included 100 patients who underwent coronary CTA using one of two protocols: (1) 50 patients underwent scanning using a conventional single-ROI bolus-tracking technique (P-single) with an ROI placed in the ascending aorta, and (2) 50 patients underwent scanning using a dual-ROI technique (P-dual) with two ROIs placed in the pulmonary trunk and the ascending aorta. CT attenuation in the ascending aorta and coronary arteries, and the interpatient variability were compared between the two scanning protocols. Read More

    The effect of Mepitel Film on acute radiation-induced skin reactions in head and neck cancer patients: a feasibility study.
    Br J Radiol 2017 Nov 8:20170298. Epub 2017 Nov 8.
    4 Department of Radiation Therapy, University of Otago , Wellington , New Zealand.
    Objective: Mepitel Film significantly decreases acute radiation-induced skin reactions in breast cancer patients. Here we investigated the feasibility of using Mepitel Film in head and neck cancer patients (ACTRN12614000932662).

    Methods: Out of a total of 36 head and neck cancer patients from New Zealand (NZ) (n = 24) and China (n = 12) recruited between June 2015 and December 2016, 33 patients complied with protocol. Read More

    Cervical cancer treated with reduced-volume intensity-modulated radiation therapy base on Sedlis criteria (NCCN VS. RTOG).
    Br J Radiol 2017 Oct 26:20170398. Epub 2017 Oct 26.
    1 Department of Radiation Oncology, FuZhou General Hospital of PLA, FuZhou, China.
    Objective: This study aimed to evaluate the clinical efficacy of different target volumes in pelvic radiotherapy in postoperative treatment of cervical cancer based on the Sedlis criteria.

    Methods: Patients who admitted to our department for postoperative radiotherapy of cervical cancer from December 2001 to December 2011 and met the Sedlis criteria were retrospectively analyzed. The incidences of acute and late radiation injuries, and overall, disease-free, and tumor-specific survival with reduced-volume pelvic and whole-pelvis radiotherapy were evaluated and compared. Read More

    Efficacy and safety of ultrasound guided percutaneous glue embolization in iatrogenic haemorrhagic complications of paracentesis and thoracocentesis in cirrhotic patients.
    Br J Radiol 2017 Nov 8:20170259. Epub 2017 Nov 8.
    3 Department of Hepatology , Institute of Liver and Biliary Sciences , New Delhi, India.
    Objective: To compare the safety and efficacy of ultrasound guided percutaneous glue (N-butyl-2-cyanoacrylate) embolization with transarterial embolization in the management of iatrogenically injured arteries while performing paracentesis or thoracocentesis in patients with chronic liver disease.

    Methods: Hospital database was searched for cirrhotic patients having abdominal/thoracic wall haemorrhage following paracentesis/thoracocentesis procedure from January 2011 to June 2016. Doppler ultrasound and/or CT angiography were used to localize the site of haemorrhage and patients were treated by transarterial embolization or ultrasound-guided percutaneous glue embolization. Read More

    Strategies for reducing ovarian dose in volumetric modulated arc therapy (VMAT) for postoperative uterine cervical cancer.
    Br J Radiol 2017 Nov 3:20160777. Epub 2017 Nov 3.
    1 Department of Radiation Oncology, Osaka International Cancer Institute, Osaka Japan.
    Objective: To reduce the ovarian dose with volumetric modulated arc therapy (VMAT), an original VMAT was designed with two types of arcs to restrict angles and fields (R-VMAT).

    Methods: The subjects were 11 patients who underwent ovarian transposition with clips left by a surgeon. Three methods, intensity-modulated radiotherapy (IMRT), standard VMAT (S-VMAT) and R-VMAT, were optimized for assessment of the ovarian dose with the target coverage kept high. Read More

    T3 subclassification using the EMD/mesorectum ratio predicts neoadjuvant chemoradiation outcome in T3 rectal cancer patients.
    Br J Radiol 2017 Nov 21:20170617. Epub 2017 Nov 21.
    1 Department of Radiation Oncology,Fudan University Shanghai Cancer Center , Fudan University Shanghai Cancer Center , Shanghai , China.
    Objective: To evaluate the feasibility of the EMD (extramural depth)/mesorectum ratio as a marker for T3 rectal cancer and its ability to predict tumour response to neoadjuvant chemoradiation and survival.

    Methods: From 2010 to 2016, 284 T3 rectal cancer patients who underwent high resolution MRI before neoadjuvant chemoradiation were enrolled. The EMD was defined as the distance from the outer edge of the muscularis propria to the outermost edge of the tumour. Read More

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