Search Our Scientific Publications & Authors

Pituitary 2022 Jun 24. Epub 2022 Jun 24.

Department of Endocrinology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, 400012, India.

Purpose: There is limited data regarding Pituitary Stalk Interruption Syndrome (PSIS) from India. Moreover, the pathophysiological link between perinatal events and PSIS is unclear. We aim to elucidate the predictors of PSIS among patients with growth hormone deficiency (GHD) and perinatal events in PSIS by comparing cohorts of PSIS and genetically proven GHD without PSIS. Read More

Sex Reprod Healthc 2022 Jun 15;33:100751. Epub 2022 Jun 15.

Department of Nursing and Health Promotion, Oslo Metropolitan University, Oslo, Norway.

Introduction: International guidelines recommend that external cephalic version (ECV) be offered to all women with single fetuses in breech presentation at term. In Norway, ECV is not offered routinely; the national clinical guidelines advice that birth units capable of offering ECV for breech pregnancies make their own practice decisions. This study was performed to determine the extent to which Norwegian birth units offer ECV to pregnant women with fetuses in breech presentations at term, and to identify factors that might influence the use of ECV. Read More

Medicine (Baltimore) 2022 Jun 17;101(24):e29421. Epub 2022 Jun 17.

Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.

Rationale: Patients with a single ventricle, who have not undergone surgery, reportedly have a lower survival rate. Furthermore, multiple pregnancies are rare among these females. We reported a case of anesthesia management of cesarean section in an uncorrected single-ventricular multi-pregnancy woman and review the anesthesia management of the published similar cases. Read More

Birth 2022 Jun 13. Epub 2022 Jun 13.

School of Nursing and Midwifery, Trinity College Dublin, Dublin, Ireland.

Background: There is widespread concern around the rising rates of cesarean births (CBs), especially among first-time mothers, despite evidence suggesting increased morbidities after birth by cesarean. There are uncertainties around factors associated with rising rates of CBs among first-time mothers in Ireland, and insight into these is essential for understanding the rising trend in CBs. Therefore, this study aimed to identify the factors associated with CBs in nulliparous women. Read More

Gynecol Obstet Fertil Senol 2022 May 27. Epub 2022 May 27.

Service de gynécologie-obstétrique, CHU de Nantes, Nantes, France; Centre d'investigation clinique CIC 1413, INSERM, CHU de Nantes, Nantes, France; Nantes université, mouvement - interactions-performance - MIP, EA4334, Nantes, France. Electronic address:

Objective: On January 2020, the French College of Gynecologists and Obstetricians (CNGOF) issued new Clinical Practice Guidelines (CPG) "Breech Presentation". Since then, it is recommended to use a tocolytic agent to improve the success rate of External Cephalic Version (ECV). The aim of this study, one year after these CPG, is to compare ECV without (before CPG) and with (after CPG) tocolysis in a type III maternity hospital. Read More

J Paediatr Child Health 2022 May 30. Epub 2022 May 30.

Penn State Hershey Medical Center, Bone and Joint Institute, Hershey, Pennsylvania, United States.

Developmental hip dysplasia (DDH) is a paediatric condition in which the 'ball and socket' hip joint fails to form properly during infancy. The increased mechanical stress on the hip joint from DDH can contribute to the development of osteoarthritis during adulthood. Therefore, careful physical examination and imaging of all infants to diagnose DDH is critical to provide the best possible functional outcome. Read More

Acta Obstet Gynecol Scand 2022 Jun;101(6):564-576

Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Gothenburg, Sweden.

Introduction: Three per cent of all infants are born in breech presentation, still the preferred way to deliver them remains controversial. The objective of this systematic review was to assess the safety for the mother and child depending on intended mode of delivery when the baby is in breech position at term.

Material And Methods: The population (P) was pregnant women with a child in breech presentation, from gestational week 34 . Read More

BMC Pediatr 2022 May 13;22(1):280. Epub 2022 May 13.

School of Public Health, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.

Background: Birth asphyxia is the inability of a newborn to start and conserve breathing immediately after birth. Globally, 2.5 million infants die within their first month of life every year, contributing nearly 47% of all deaths of children. Read More

J Gynecol Obstet Hum Reprod 2022 Jun 6;51(6):102404. Epub 2022 May 6.

CHU Lille, Department of Obstetrics, F-59000, Lille, France; University of Lille, EA 2694 - METRICS, F-59000, Lille, France.

Objective: Breech presentation at term accounts for around 5% of births. Few studies have evaluated the effectiveness of different induction methods for breech presentations. We aim to compare the mode of delivery after induction by intra cervical dilatation balloon compared to prostaglandin (PGE2) in breech presentation. Read More

Arch Gynecol Obstet 2022 Apr 27. Epub 2022 Apr 27.

Service de Gynécologie Obstétrique, Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Paris, France.

Purpose: To assess severe neonatal morbidity and mortality in induced labor in preterm breech deliveries, compared to spontaneous labor.

Methods: This is a retrospective study conducted in a tertiary university center in France. Women with single live breech pregnancy between 28 + 0 and 36 + 6 weeks gestation were included. Read More

Sex Reprod Healthc 2022 Jun 1;32:100724. Epub 2022 Apr 1.

Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway; Center for Fetal Medicine, Trondheim University Hospital (St. Olav's Hospital), Trondheim, Norway; Department of Obstetrics and Gynecology, Stavanger University Hospital, Stavanger, Norway.

Objective: To investigate outcomes in spontaneous and induced twin deliveries. Secondary aims were to study impact of delivery interval and breech presentation of the first twin.

Methods: This retrospective cohort study comprised 354 twin deliveries at a tertiary Norwegian hospital. Read More

J Gynecol Obstet Hum Reprod 2022 May 9;51(5):102377. Epub 2022 Apr 9.

Univ. Lille, CHU Lille, ULR 2694, METRICS-Evaluation des technologies de santé et des pratiques médicales, F-59000 Lille, France; CHU Lille, Department of Obstetrics, F-59000 Lille, France.

Background: Breech presentation of the first twin occurs in 20% of twin pregnancies. However, the impact of delivery mode on morbimortality in breech fetuses remains controversial in the literature generally, and has been infrequently studied in twin pregnancies specifically. The aim herein was to evaluate neonatal and maternal outcomes according to delivery mode when the first twin was in breech presentation, and to compare these results with those in the current literature. Read More

Am J Obstet Gynecol MFM 2022 07 8;4(4):100640. Epub 2022 Apr 8.

Department of Obstetrics and Gynecology, Hadassah Hebrew University Medical Center, Mount-Scopus, Jerusalem, Israel (Drs Hochler, Suissa-Cohen, Lipschuetz, Yagel, and Walfisch).

Background: Maternal and neonatal outcomes of trial of labor after cesarean delivery of twins are similar to those of singleton trials of labor after cesarean delivery. However, previous studies did not stratify outcomes by second-twin presentation on admission to labor.

Objective: To examine maternal and neonatal outcomes following trial of labor after cesarean delivery in twins with vertex-nonvertex presentation. Read More

Trials 2022 Apr 4;23(1):249. Epub 2022 Apr 4.

, London, UK.

Background: Women pregnant with a breech-presenting foetus at term are at increased risk of adverse pregnancy outcomes. The most common intervention used to improve neonatal outcomes is planned delivery by caesarean section. But this is not always possible, and some women prefer to plan a vaginal birth. Read More

Orthop Clin North Am 2022 Apr 5;53(2):167-177. Epub 2022 Mar 5.

Department of Orthopaedics, The Ohio State University Wexner Medical Center, 700 Children's Drive, T2E- A2700, Columbus, OH 43205, USA; Department of Orthopedic Surgery, Nationwide Children's Hopsital, Columbus, OH, USA. Electronic address:

Brachial plexus birth injuries (BPBIs) are typically traction type injuries to the newborn that occur during the delivery process. Although the incidence of these injuries has overall decreased from 1.5 to around 0. Read More

BMC Pediatr 2022 03 30;22(1):165. Epub 2022 Mar 30.

Asrat Woldeyus Health Science Campus, School of Medicine, Debre Berhan University, Debre Berhan, Ethiopia.

Background: Birth asphyxia is the major public health problem in the world. It is estimated that around 23% of all newborn deaths are caused by birth asphyxia worldwide. Birth asphyxia is the top three causes of newborn deaths in sub-Saharan Africa and more than one-third of deaths in Ethiopia. Read More

Indian Pediatr 2022 Mar 28. Epub 2022 Mar 28.

Department of Gynaecology, Thanawala Maternity Home, Vashi, Navi Mumbai, Maharashtra.

Justification: When developmental dysplasia of the hip (DDH) is diagnosed during infancy, conservative management is often successful, with good long-term outcomes. In India, DDH is often not diagnosed until walking age and there are limited guidelines for its screening.

Process: A multidisciplinary Expert Group consisting of members of the Paediatric Orthopaedic Society of India, Indian Academy of Pediatrics, National Neonatology Forum of India, Indian Radiological and Imaging Association, Indian Federation of Ultrasound in Medicine and Biology, Federation of Obstetric and Gynaecological Societies of India, and Indian Orthopaedic Association worked collaboratively to develop surveillance guidelines for DDH. Read More

Arch Gynecol Obstet 2022 Mar 27. Epub 2022 Mar 27.

Department of Obstetrics, Charité Hospital, Humboldt University, Berlin, Germany.

Purpose: This study aims to evaluate the level of psychological distress for women with breech compared to cephalic presentation. We hypothesized, that women with breech presentation have higher levels of depression, stress and anxiety. Secondary objectives were to analyze potential demographic risk factors and comorbidity of psychological distress in breech pregnancy. Read More

Eur J Obstet Gynecol Reprod Biol 2022 May 8;272:166-172. Epub 2022 Mar 8.

Department of Clinical Sciences, Division of Obstetrics and Gynecology, Karolinska Institutet, Danderyd Hospital, S-182 88 Stockholm, Sweden; The Institute for Evaluation of Labor Market and Education Policy (IFAU), S-751 20 Uppsala, Sweden. Electronic address:

Objective: The aim of this study was to examine the association between delivery mode and severe maternal and neonatal morbidity in singleton term breech births.

Study Design: This nationwide population-based cohort study includes 41 319 singleton term and post-term breech births (37 + 0-42 + 6 gestational weeks) in Sweden from 1998 to 2016. Data was retrieved from the Swedish Medical Birth Register. Read More

Eur J Obstet Gynecol Reprod Biol 2022 May 11;272:156-159. Epub 2022 Mar 11.

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, United States.

Background: External cephalic version (ECV) is a technique used to reduce the incidence of cesarean deliveries due to malpresentation. Nitrous oxide is an inhaled analgesic that may be used for pain relief for women undergoing external cephalic version.

Objective: To compare the conversion rate of non-cephalic to cephalic presentation in ECV with and without nitrous oxide. Read More

Ecotoxicol Environ Saf 2022 Mar 14;234:113408. Epub 2022 Mar 14.

Key Laboratory of Health Ministry for Congenital Malformation, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang, Liaoning 110004, China.

The etiology of developmental dysplasia of the hip (DDH) is multifactorial, including breech presentation and hip capsular laxity. In particular, hip laxity is the main contributor to DDH by changing the ratio and distribution of collagens. Also, fluoride (F) affects collagens from various tissue besides bone and tooth. Read More

BMC Pregnancy Childbirth 2022 Mar 16;22(1):211. Epub 2022 Mar 16.

Department of Obstetrics and Gynecology, University Hospital (HUS), University of Helsinki, Haartmaninkatu 2, 00290, Helsinki, Finland.

Background: In many countries, vaginal breech labor at term is an option in selected cases. However, the safety of vaginal breech labor in preterm is still unclear. Therefore our study aimed to evaluate the safety of vaginal breech labor in late preterm deliveries. Read More

Acta Obstet Gynecol Scand 2022 Jul 16;101(7):827-835. Epub 2022 Mar 16.

Department of Obstetrics and Gynecology, Danderyd Hospital, Stockholm, Sweden.

Introduction: The Robson Ten Group Classification System is widely used for the audit of cesarean section (CS) rates. However, CS rate alone is a poor quality indicator and should be balanced with other obstetric endpoints. The aim of this study was to evaluate whether Swedish national data on obstetric outcomes other than CS, stratified by the Robson classification, could be analyzed in a useful way. Read More

PLoS One 2022 14;17(3):e0262002. Epub 2022 Mar 14.

Department of Obstetrics and Gynecology, Jean Minjoz Hospital, Besançon University Medical Center-Alexander Fleming Boulevard, Besançon, France.

Background: Cervical dilatation curves are widely used to describe normal and abnormal labor progression for cephalic presentation. Labor curves for breech presentations have never been described.

Objectives: The aims of this study were to examine the pattern of labor progression in women with a breech presentation and to determine whether the type of breech or parity can influence the speed of cervical dilatation. Read More

J Matern Fetal Neonatal Med 2022 Mar 13:1-7. Epub 2022 Mar 13.

Department of Obstetrics and Gynecology, Emek Medical Center, Afula, Israel.

Introduction: Several adjuvant interventions have been evaluated for improving the success rate of the external cephalic version (ECV) and reducing the rate of cesarean delivery (CD). Evidence regarding the effect of Nitrous oxide is limited to a small number of participants with inconsistent results on pain score and success rate. This study aims to examine the effect of inhaled nitrous oxide on the success rate and pain score for women undergoing ECV. Read More

J Matern Fetal Neonatal Med 2022 Mar 2:1-8. Epub 2022 Mar 2.

Longgang District Maternal & Child Healthcare Hospital of Shenzhen City, Shenzhen, China.

Aims: To address the rate of spontaneous version in breech presentation until term and explore the risk factors for persistent breech presentation diagnosed by the second-trimester ultrasound examination.

Methods: This is a retrospective cohort study of pregnant women with a singleton pregnancy who had their ultrasound examination conducted at the time of 22-26 weeks of gestation in the Guangzhou Women and Children's Medical Center. Cox regressions were applied to determine the strength of association between selected risk factors and persistent breech presentation. Read More

Ann R Coll Surg Engl 2022 Jun 17;104(6):e187-e189. Epub 2022 Feb 17.

The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, UK.

We report the case of a five-month-old girl presenting with a subluxed left hip following normal neonatal clinical examination and serial ultrasound screening. Her only risk factor for developmental dysplasia of the hip (DDH) was breech presentation. She underwent closed reduction with successful concentric reduction. Read More

Med Arch 2021 Oct;75(5):386-389

Academy of Medical Sciences of Bosnia and Herzegovina, Sarajvo, Bosnia and Herzegovina.

Background: The peculiar reigning and private life of Maria Theresa in the tumultuous time of continuous wars in the then Europe was interwoven with her predominant maternal/obstetric history, as presented below.

Objective: All the sixteen pregnancies of Empress Maria Theresa ended in spontaneous vaginal deliveries at term, with no information on pregnancies ended in spontaneous abortion or preterm delivery.

Methods: Medicohystorical review of the obstetrical anamnesis of Empress Maria Theresia. Read More

J Clin Med 2022 Jan 28;11(3). Epub 2022 Jan 28.

Dutch Reference Center for Prader-Willi Syndrome Westzeedijk 106, 3016 AH Rotterdam, The Netherlands.

Objective: Prader-Willi syndrome (PWS) is a rare genetic syndrome with a wide spectrum of clinical features in early life. Late diagnoses are still present. We characterized the perinatal and neonatal features of PWS, compared them with those of healthy newborns and assessed the prenatal and neonatal differences between the genetic subtypes. Read More

J Clin Med 2022 Jan 19;11(3). Epub 2022 Jan 19.

Department of Obstetrics and Gynecology, 'Virgen de la Arrixaca' University Hospital, 30120 Murcia, Spain.

Although the influence of neuraxial anesthesia or sedation with remifentanil in external cephalic version (ECV) is widely known, ECV results using propofol have not been previously analyzed. This study aimed to evaluate ECV outcomes when propofol was used. An observational analysis of ECV was performed between 1 January 2018 and 31 December 2020. Read More