67 results match your criteria Breast Stereotactic Core Biopsy Fine Needle Aspiration

Advances in Breast Imaging with Current Screening Recommendations and Controversies.

Obstet Gynecol Clin North Am 2022 Mar;49(1):1-33

WVU Department of Radiology, West Virginia University School of Medicine, PO Box 9235, Morgantown, WV 26506, USA; Breast Imaging Fellowship Director, WVU Department of Radiology; Associate Professor of Radiology, West Virginia University School of Medicine. Electronic address:

In the last several decades, breast imaging has undergone transformation. Technological advances in mammography and ultrasound and the development and increased availability of imaging modalities used in supplemental screening and diagnostic settings, including tomosynthesis and breast MRI, have allowed for improved breast cancer detection and diagnosis. Image-guided core breast biopsies have largely replaced fine needle aspirations. Read More

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Imaging of Intracystic Papillary Carcinoma.

Curr Probl Diagn Radiol 2019 Jul - Aug;48(4):348-352. Epub 2018 May 22.

The University of Texas MD Anderson Cancer Center, Department of Diagnostic Radiology, Division of Diagnostic Imaging, Houston, TX. Electronic address:

Objective: To describe the clinical, imaging, and histopathologic findings of intracystic papillary carcinoma (IPC) of the breast.

Materials And Methods: Following institutional review board approval, a database at a single institution was searched to identify cases of patients who received a diagnosis of IPC from 1999-2013 and who had undergone preoperative imaging with mammography, sonography, or MRI. The clinical, mammographic, sonographic, and MRI features of IPC were compared and analyzed using the BI-RADS mammography, ultrasound, and MRI lexicons. Read More

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December 2019

Biopsy Feasibility Trial for Breast Cancer Pathologic Complete Response Detection after Neoadjuvant Chemotherapy: Imaging Assessment and Correlation Endpoints.

Ann Surg Oncol 2018 Jul 17;25(7):1953-1960. Epub 2018 Apr 17.

Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Purpose: This study was designed to present the secondary imaging endpoints of the trial for evaluating mammogram (MMG), ultrasound (US) and image guided biopsy (IGBx) assessment of pathologic complete response (pCR) in breast cancer (BC) patients undergoing neoadjuvant chemotherapy (NAC).

Methods: Patients with T1-3, N0-3, M0 triple-negative or HER2-positive BC who received NAC were enrolled in an Institutional Review Board-approved prospective, clinical trial. Patients underwent US and MMG at baseline and after NAC. Read More

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Advances in breast intervention: where are we now and where should we be?

Clin Radiol 2018 08 8;73(8):724-734. Epub 2017 Dec 8.

Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Geert Grooteplein 10, Nijmegen, The Netherlands. Electronic address:

In the past four decades, a variety of methods for minimal or non-invasive diagnosis and treatment of breast cancer have been introduced. Although breast imaging has become more and more specific for diagnosis, specimen biopsy with histopathological confirmation is still necessary. Core-needle biopsy under ultrasound guidance is the appropriate first choice for the diagnosis of most lesions. Read More

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Mucocele-like lesions in the breast diagnosed with percutaneous biopsy: is surgical excision necessary?

AJR Am J Roentgenol 2015 Jan;204(1):204-10

1 Tufts University School of Medicine, Boston, MA.

Objective: The purpose of this study was to determine the frequencies of atypia and cancer at excisional biopsy of lesions with a diagnosis of mucocele-like lesion (MLL) at percutaneous breast biopsy.

Materials And Methods: Retrospective review of 9286 lesions subjected to percutaneous imaging-guided biopsy identified MLLs in 35 (0.38%) patients. Read More

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January 2015

Vacuum-assisted breast biopsy for breast cancer.

Gland Surg 2014 May;3(2):120-7

Department of Surgery, Kangnam CHA Hospital, CHA University College of Medicine, Seoul, Korea.

Sonographic examination of the breast with state-of-the-art equipment has become an essential part of the clinical work-up of breast lesions and a valuable adjunct to mammographic screening and physical examination. Fine-needle aspiration (FNA) and core-needle biopsy (CNB) are well-established, valuable techniques that are still used in most cases, whereas vacuum-assisted breast biopsy (VABB) is a more recent technique. VABB has proven clinical value and can be used under sonographic, mammographic, and magnetic resonance imaging guidance. Read More

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Predictors of pain experienced by women during percutaneous imaging-guided breast biopsies.

J Am Coll Radiol 2014 Jul;11(7):709-16

Department of Radiology, Duke University Medical Center, Durham, North Carolina. Electronic address:

Purpose: The purpose of this study was to evaluate pain experienced during imaging-guided core-needle breast biopsies and to identify factors that predict increased pain perception during procedures.

Methods: In this institutional review board-approved, HIPAA-compliant protocol, 136 women undergoing stereotactically or ultrasound-guided breast biopsy or cyst aspiration were recruited and provided written informed consent. Participants filled out questionnaires assessing anticipated biopsy pain, ongoing breast pain, pain experienced during biopsy, catastrophic thoughts about pain during biopsy, anxiety, perceived communication with the radiologist, chronic life stress, and demographic and medical information. Read More

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Flat ductal intraepithelial neoplasia 1A diagnosed at stereotactic core needle biopsy: is excisional biopsy indicated?

AJR Am J Roentgenol 2013 Mar;200(3):682-8

Department of Radiology, University of British Columbia, Vancouver, BC, Canada.

Objective: This study correlates ductal intraepithelial neoplasia (DIN) 1A diagnosed at stereotactic spring core needle biopsy (CNB) or vacuum-assisted biopsy (VAB) with the subsequent surgical histologic results or long-term follow-up imaging findings to predict the likelihood of upgrade to ductal carcinoma in situ (DCIS) or invasive carcinoma.

Materials And Methods: Stereotactic imaging-guided CNBs and VABs were performed principally for assessment of microcalcifications seen on mammography. DIN 1A diagnoses made at CNB or VAB were correlated with subsequent excisional biopsy results or imaging follow-up. Read More

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Breast imaging for interventional pathologists.

David Lieu

Arch Pathol Lab Med 2013 Jan 26;137(1):100-19. Epub 2012 Apr 26.

Fine Needle Aspiration Medical Group, Alhambra, California 91801, USA.

Context: Pathologist-performed, ultrasound-guided fine-needle aspiration biopsy is one of the frontiers of pathology. The College of American Pathologists, American Society for Clinical Pathology, and American Society of Cytopathology offer courses and certificate programs for pathologists in this area. The courses emphasize the biopsy of masses in the thyroid and head and neck. Read More

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January 2013

Stereotactic core biopsy: Comparison of 11 gauge with 8 gauge vacuum assisted breast biopsy.

Eur J Radiol 2012 Oct 27;81(10):2613-9. Epub 2011 Nov 27.

Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA.

Purpose: The compare the performance and ability to obtain a correct diagnosis on needle biopsy between 11 gauge and 8 gauge vacuum assisted biopsy devices.

Materials And Methods: Hospital records of all consecutive stereotactic core biopsies performed over five years were retrospectively reviewed in compliance Health Insurance Portability and Accountability Act (HIPPA) policy and with approval from the hospital institutional review board (IRB). Pathology from core biopsy was compared with surgical pathology and/or imaging follow-up. Read More

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October 2012

Image-guided breast biopsy: state-of-the-art.

Clin Radiol 2010 Apr;65(4):259-70

South East London Breast Screening Programme and National Breast Screening Training Centre, Kings College Hospital NHS Foundation Trust, London SE5 9RS, UK.

Percutaneous image-guided breast biopsy is widely practised to evaluate predominantly non-palpable breast lesions. There has been steady development in percutaneous biopsy techniques. Fine-needle aspiration cytology was the original method of sampling, followed in the early 1990s by large core needle biopsy. Read More

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Clinical implications of subcategorizing BI-RADS 4 breast lesions associated with microcalcification: a radiology-pathology correlation study.

Breast J 2010 Jan-Feb;16(1):28-31. Epub 2009 Nov 19.

Department of Pathology, University of Louisville, Louisville, Kentucky 40202, USA.

Currently radiologists have the option of subcategorizing BI-RADS 4 breast lesions into 4A (low suspicion for malignancy), 4B (intermediate suspicion of malignancy), and 4C (moderate concern, but not classic for malignancy). To determine the clinical significance of BI-RADS 4 subcategories and the common pathologic changes associated with these mammographic lesions, a retrospective review of 239 consecutive stereotactic-needle core biopsies (SNCB) for microcalcifications was performed. All 239 SNCBs were BI-RADS 4 lesions, and of these, 191 were subcategorized to 4A, 4B or 4C. Read More

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Biopsy method: a major predictor of adherence after benign breast biopsy?

AJR Am J Roentgenol 2009 Nov;193(5):W452-7

Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, School of Medicine, University of Athens, Greece, Ampelokipi, Athens 11521, Greece.

Objective: Adopting a longitudinal approach to assess women after breast biopsy with a benign result, this study aimed to comparatively evaluate the effect of the biopsy method on compliance with clinical recommendations for follow-up.

Materials And Methods: For this study, 410 patients who underwent biopsy of a breast lesion were included: fine-needle aspiration biopsy, n = 95 patients; core biopsy, n = 84; local excision under local anesthesia, n = 72; vacuum-assisted breast biopsy, n = 100; and hookwire localization, n = 59. Information about patient age, place of residence, whether complications occurred, and type of lesion was collected. Read More

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November 2009

Breast cancer seeding associated with core needle biopsies: a systematic review.

Maturitas 2009 Feb 22;62(2):113-23. Epub 2009 Jan 22.

Breast Unit, ISALA Breast Cancer Prevention Center and High Risk Clinic Dept OB-Gyn, St. Pierre University Hospital, Haute Str. 290, B-1000 Brussels, Belgium.

Background: Preoperative diagnosis has become the standard in breast cancer (BC) management. Recently, ultrasound guided core needle biopsy (CNB) and stereotactic needle core biopsy have replaced fine needle aspiration cytology. Epithelial cell displacement (DE) occurs frequently after core needle biopsy (CNB) for breast cancer diagnosis. Read More

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February 2009

Frequency and upgrade rates of atypical ductal hyperplasia diagnosed at stereotactic vacuum-assisted breast biopsy: 9-versus 11-gauge.

AJR Am J Roentgenol 2009 Jan;192(1):229-34

Department of Radiology, University of Washington Medical Center, Seattle, WA, USA.

Objective: Our goals were to determine the frequency and upgrade rate for atypical ductal hyperplasia (ADH) diagnosed with stereotactic 9-gauge vacuum-assisted breast biopsy and to compare the frequencies and upgrade rates of ADH between 9- and 11-gauge vacuum-assisted breast biopsy.

Materials And Methods: We retrospectively reviewed the pathology results of 991 consecutive 9- or 11-gauge stereotactic vacuum-assisted breast biopsy procedures from February 2001 through June 2006 and identified lesions diagnosed as ADH. The final diagnosis after surgical excision was determined from medical records. Read More

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January 2009

Large-core needle biopsy versus fine-needle aspiration biopsy in solid breast lesions: comparison of costs and diagnostic value.

Acta Radiol 2008 Oct;49(8):863-9

Medical Imaging Centre, Department of Radiology, Pirkanmaa Hospital District, Tampere, Finland.

Background: In the current climate of budget constraints and personnel shortages, hospitals are required to demonstrate ever-greater cost effectiveness. In the diagnosis of breast lesions, it is useful to compare the costs and benefits of fine-needle aspiration biopsy (FNAB) and core-needle biopsy (CNB).

Purpose: To determine the total costs of FNAB and CNB of breast lesions, and to compare the costs and diagnostic value of these methods. Read More

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October 2008

Evaluation and indications of ultrasound-guided vacuum-assisted core needle breast biopsy.

Breast Cancer 2007 ;14(3):292-6

Department of Surgery, Kawaguchi Municipal Medical Center, Kawaguchi-city, Saitama, Japan.

Background: The Mammotome is a diagnostic tool used under stereotactic or with ultrasound guidance. A clear indication for Mammotome use under stereotactic guidance is when a non-palpable microcalcification is a target. However, the indications for the use of the Mammotome under ultrasound guidance vary among institutions, and it is difficult to find a place for the Mammotome among conventional biopsy techniques. Read More

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November 2007

Ultrasound imaging features of radial scars of the breast.

Australas Radiol 2007 Jun;51(3):240-5

Department of Diagnostic and Interventional Radiology, Royal Perth Hospital, Perth, Western Australia, Australia.

Radial scars of the breast are common benign lesions, which are often radiologically occult. When they are detected by imaging, they are most often found by mammography. Radial scars are usually impalpable and have traditionally been localized for core biopsy and hookwire placement preoperatively by mammographic guidance. Read More

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A decade of breast cancer screening in The Netherlands: trends in the preoperative diagnosis of breast cancer.

Breast Cancer Res Treat 2007 Nov 12;106(1):113-9. Epub 2007 Jan 12.

Department of Radiology, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, The Netherlands.

Purpose: In a prospective, multi-institutional follow-up study we describe the trends in the preoperative pathologic confirmation of breast cancer of women who underwent breast cancer screening between 1995 and 2005.

Methods: We included all women aged 50-75 years who underwent biennial screening mammography in the southern breast cancer screening region of the Netherlands between February 13, 1995 and December 22, 2004. Clinical data, breast imaging reports, biopsy results and breast surgery reports were collected of all women with a positive screening result. Read More

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November 2007

Cost-effective use of breast biopsy techniques in a Veterans health care system.

Am J Surg 2006 Nov;192(5):e37-41

Department of General Surgery, VA Tennessee Valley Healthcare System, CCC-4312 Medical Center North, Nashville, TN 37232-2730, USA.

Background: Breast health has become an increasingly important issue among the veteran population. Options for the evaluation of a breast mass or a suspicious mammographic finding include open surgical biopsy at the Veterans Affairs (VA) hospital or percutaneous image-guided biopsy at an affiliated academic institution. We examined the costs and trends in the use of surgical versus percutaneous image-guided biopsy procedures in this diagnostic algorithm. Read More

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November 2006

Accuracy and underestimation of malignancy of breast core needle biopsy: the Florence experience of over 4000 consecutive biopsies.

Breast Cancer Res Treat 2007 Mar 6;101(3):291-7. Epub 2006 Jul 6.

Centro per lo Studio e la Prevenzione Oncologica (CSPO), Florence, Italy.

Breast core needle biopsy (CNB) is used for sampling breast lesions in both the screening and diagnostic context. We present the accuracy of breast CNB from a consecutive series of 4035 core biopsies, using methods that minimise selection and verification bias. We calculate accuracy and underestimation of malignancy for both automated (14G) and directional vacuum-assisted (11G) CNB performed under stereotactic or sonographic guidance. Read More

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Quality of diagnosis and surgical management of breast lesions in a community hospital: room for improvement?

Can J Surg 2006 Jun;49(3):185-92

Division of General Surgery, Department of Surgery, McMaster University, Hamilton, Ont.

Background: We aimed to examine both the diagnostic modalities used to identify breast lesions and their surgical management in an Ontario community hospital.

Methods: We conducted a retrospective chart review of the preoperative diagnostic tools used by 6 general surgeons for palpable and nonpalpable breast lesions and considered the types of surgical procedures performed. Patients who underwent noncosmetic breast surgery in the year 2000 were included in the study (n = 180). Read More

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Significance of papillary lesions at percutaneous breast biopsy.

Ann Surg Oncol 2006 Apr 14;13(4):480-2. Epub 2006 Feb 14.

Department of Surgery, Comprehensive Breast Service, St. Luke's Roosevelt Medical Center, 425 West 59th Street Suite 7A, New York, New York 10019, USA.

Background: The management of nonpalpable papillary lesions found in specimens obtained by percutaneous breast biopsy is controversial. We reviewed the treatment of patients found to have papillary lesions by stereotactic, sonographic, or fine-needle aspiration breast biopsy to identify indications for surgical excision.

Methods: Consecutive patients with intraductal papilloma, atypical papilloma/papilloma with atypical ductal hyperplasia, papillary neoplasm, and papillomatosis according to percutaneous breast biopsy were identified from radiology records. Read More

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Management of melanoma metastasis to the breast: case series and review of the literature.

Br J Dermatol 2005 Jun;152(6):1206-10

Skin Oncology Service, University Hospital Birmingham NHS Trust, Birmingham B29 6JD, UK.

Background: Metastases to the breast from extramammary cancers are rare; melanoma is one of the malignancies that can metastasize to the breast.

Objectives: To examine the records of a series of patients with a previous diagnosis of melanoma and a metastasis to the breast, and review the published literature of this condition.

Methods: We report details of eight female patients with breast metastases from melanoma seen over a 36-month period from 2001. Read More

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Trends in recall, biopsy, and positive biopsy rates for screening mammography in an academic practice.

Radiology 2005 May 15;235(2):396-401. Epub 2005 Mar 15.

Department of Radiology, University of Pittsburgh and Magee-Womens Hospital of the University of Pittsburgh Medical Center, 300 Halket Street, Imaging Research, Suite 4200, Pittsburgh, PA 15213-3180, USA.

Purpose: To retrospectively evaluate whether recall, biopsy, and positive biopsy rates for a group of radiologists who met requirements of Mammography Quality Standards Act of 1992 (MQSA) demonstrated any change over time during a 27-month period (nine consecutive calendar quarters).

Materials And Methods: Institutional review board approved study protocol, and informed consent was waived. All screening mammograms that had been interpreted by MQSA-qualified radiologists between January 1, 2001, and March 31, 2003, were reviewed. Read More

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Percutaneous breast biopsy for nonpalpable lesions.

Breast Dis 1998 Aug;10(3-4):67-81

Department of Radiology, University of Virginia, Charlottesville, VA, USA.

Increasingly, biopsies for suspected breast abnormalities are conducted by percutaneous needle extraction of core samples rather than by standard surgical excision or fine-needle aspiration (FNA) of cellular material. Core-needle biopsies are highly accurate and have many advantages over surgical excisions, including reduction of the morbidity and cost of breast disease diagnosis. Limitations include differentiating atypical ductal hyperplasia from ductal carcinoma in situ. Read More

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Practicing breast imaging in HRT ladies in Thailand.

J Med Assoc Thai 2004 Oct;87 Suppl 3:S169-73

Faculty of Medicine Siriraj Hospital, Bangkok 10700, Thailand.

The incidence of breast cancer in Thai women increased significantly each year. The statistic from Siriraj Cancer Institute, it was 6.8% of female cancers in 1985 and became 20. Read More

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October 2004

How stereotactic core-needle biopsy affected breast fine-needle aspiration utilization: an 11-year institutional review.

Diagn Cytopathol 2004 Aug;31(2):106-10

Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA.

To determine the effect of stereotactic core-needle biopsy (SCNB) on the utilization of breast fine-needle aspirate (FNA) biopsy, we retrospectively reviewed 1,568 cases of breast FNAs that were obtained from 1,188 patients between the years 1990 and 2000. There were 378 positive and atypical cases and 497 negative and unsatisfactory cases in the pre-SCNB group (between 1990 and 1996; 7 years); and 225 positive and atypical cases and 468 negative and unsatisfactory cases in the post-SCNB group (between 1997 and 2000; 4 years). The average number of cases per year in the pre- and post-SCNB groups was 125 and 173, respectively. Read More

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Stereotactic and sonographic large-core biopsy of nonpalpable breast lesions: results of the Radiologic Diagnostic Oncology Group V study.

Acad Radiol 2004 Mar;11(3):293-308

Department of Radiology, Johns Hopkins University, Baltimore, MD, USA.

Rationale And Objectives: To determine the diagnostic accuracy of stereotactically and sonographically guided core biopsy (CB) for the diagnosis of nonpalpable breast lesions.

Materials And Methods: Twenty-two institutions enrolled 2,403 women who underwent imaging-guided fine needle aspiration followed by imaging-guided large-CB of nonpalpable breast abnormalities. All mammograms were reviewed for study eligibility by one of two breast imaging radiologists. Read More

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