3,751 results match your criteria Breast J[Journal]


Update on multi-gene panel testing and communication of genetic test results.

Authors:
Sonya Reid Tuya Pal

Breast J 2020 Jul 8. Epub 2020 Jul 8.

Vanderbilt University Medical Center, Nashville, Tennessee.

With technological advances, multi-gene panel testing has become increasingly used to identify patients at risk for hereditary breast cancer (HBC). There are currently evidence-based interventions and breast cancer screening strategies that exist for cancer prevention and early detection among patients with HBC. Moreover, in addition to the personal impact of identifying HBC, this information may be shared with at-risk family members to amplify the benefits of testing and subsequent care among those at high risk. Read More

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http://dx.doi.org/10.1111/tbj.13971DOI Listing

Rebound lymphocytosis in a patient with chronic lymphocytic leukemia after cessation of a CDK 4/6 inhibitor for concomitant breast cancer.

Breast J 2020 Jul 8. Epub 2020 Jul 8.

Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

Herein, we present the case of a female with co-occurring chronic lymphocytic leukemia (CLL) and metastatic ER/PR-positive breast cancer, who when taken off palbociclib for severe neutropenia and infectious complications, experienced rebound lymphocytosis. Though this was ultimately a benign clinical outcome, it exemplifies how CDK4/6 inhibitors induce a cell cycle arrest by decreasing the proliferation of hematopoietic stem cells (HSC), in this case CLL cells, with recovery of counts once drug is stopped. Read More

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http://dx.doi.org/10.1111/tbj.13955DOI Listing

Medical Management of newly diagnosed breast cancer in a BRCA1/2 mutation carrier.

Breast J 2020 Jul 6. Epub 2020 Jul 6.

Beth Israel Deaconess Medical Center, Boston, Massachusetts, US.

Germline BRCA1/2 mutations may be infrequent in unselected breast cancer population but are concentrated in those with triple-negative breast cancer or high-risk family history. Insight into the biology of BRCA mutation is now allowing a targeted therapeutic approach to these carriers with breast cancer. Functional BRCA genes play a critical role in DNA damage repair. Read More

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http://dx.doi.org/10.1111/tbj.13972DOI Listing

Special type breast carcinoma: Sebaceous carcinoma of the breast; A case report and review of literature.

Breast J 2020 Jul 4. Epub 2020 Jul 4.

General Surgery Department, Saint George Hospital University Medical Center, University of Balamand, Beirut, Lebanon.

Sebaceous carcinoma of the breast is an extremely rare tumor. To the best of our knowledge only 15 cases have been reported in literature. Herein, we report a case of sebaceous carcinoma of the breast and describe the histopathologic features of sebaceous carcinoma of the breast in an elderly female. Read More

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http://dx.doi.org/10.1111/tbj.13963DOI Listing

The evolution of breast prostheses.

Breast J 2020 Jul 1. Epub 2020 Jul 1.

Department of Medical Biotechnology and Translational Medicine BIOMETRA - Plastic Surgery Unit, Reconstructive and Aesthetic Plastic Surgery School, Humanitas Clinical and Research Hospital, University of Milan, Milan, Italy.

Every year approximately 1.5 million prostheses are implanted worldwide for breast augmentation and reconstructive indications. The modern breast implant as we know was released to the open market in 1963. Read More

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http://dx.doi.org/10.1111/tbj.13954DOI Listing

Utility of health services regions in examining socioeconomic disparities in receipt of breast reconstruction.

Breast J 2020 Jul 1. Epub 2020 Jul 1.

Department of Surgery, Wisconsin Surgical Outcomes Research Program, University of Wisconsin, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1111/tbj.13959DOI Listing

Syringomatous tumor of the nipple-areolar complex: mammographic, ultrasonographic, and MRI manifestations.

Breast J 2020 Jun 28. Epub 2020 Jun 28.

Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1111/tbj.13951DOI Listing

The patient's pathway for breast cancer in the COVID-19 era: An Italian single-center experience.

Breast J 2020 Jun 28. Epub 2020 Jun 28.

Department of Breast Cancer Surgery, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.

COVID-19 has been declared a pandemic by the World Health Organization. As of April 1, 2020, Italy was the country with the second highest number of cases in the world. The spread of COVID-19 has required a rapid reorganization of health service delivery in face of the pandemic. Read More

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http://dx.doi.org/10.1111/tbj.13958DOI Listing

Low-grade myofibroblastic sarcoma of the breast.

Breast J 2020 Jun 28. Epub 2020 Jun 28.

Centro Integrato di Senologia, Dipartimento Scienze della Salute della Donna, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

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http://dx.doi.org/10.1111/tbj.13956DOI Listing

Leiomyoma cutis of breast.

Breast J 2020 Jun 28. Epub 2020 Jun 28.

Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1111/tbj.13947DOI Listing

Pleomorphic lobular carcinoma in situ composed of signet ring cells mimicking cribriform ductal carcinoma in situ.

Breast J 2020 Jun 26. Epub 2020 Jun 26.

Department of Pathology, Baylor Scott and White Health, Gainesville, Florida, USA.

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http://dx.doi.org/10.1111/tbj.13935DOI Listing

Extraordinary emergency measures set up by a Breast Unit to prevent COVID-19: Report of our experience.

Breast J 2020 Jun 25. Epub 2020 Jun 25.

Breast Unit Department, Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy.

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http://dx.doi.org/10.1111/tbj.13920DOI Listing

Metastatic breast cancer presented as great toenail pyogenic granuloma.

Breast J 2020 Jun 24. Epub 2020 Jun 24.

Department of Surgery, Dankook University College of Medicine, Cheonan, Republic of Korea.

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http://dx.doi.org/10.1111/tbj.13903DOI Listing

Metastatic triple-negative breast cancer: Established and emerging treatments.

Breast J 2020 Jun 23. Epub 2020 Jun 23.

Houston Methodist Cancer Center, Houston, Texas, USA.

Metastatic triple-negative breast cancer (mTNBC) patients tend to have a poor overall survival. The primary goals of treatment focus on palliation of symptoms and improvement in overall survival (OS). Single-agent sequential chemotherapy with anthracycline or taxane has remained the cornerstone of treatment for many years. Read More

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http://dx.doi.org/10.1111/tbj.13946DOI Listing

Clinicopathologic update of calcium oxalate in breast: A 15-year retrospective review.

Breast J 2020 Jun 21. Epub 2020 Jun 21.

Department of Pathology and Laboratory Medicine, Rhode Island Hospital and Lifespan Medical Center, Warren Alpert Medical School of Brown University, Providence, RI, USA.

Mammary malignancies are radiologically detected by presence of masses, architectural distortions or microcalcifications. Unlike calcium hydroxyapatite, calcium oxalate (CaOx) deposits have been almost exclusively associated with benign mammary processes. The etiology and mechanism of mammary CaOx deposition remains poorly understood, and the original studies elucidating its histopathologic correlation are dated several decades ago. Read More

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http://dx.doi.org/10.1111/tbj.13952DOI Listing

Overall survival and related prognostic factors for familial breast cancer patients: A single institution study in Iran.

Breast J 2020 Jun 21. Epub 2020 Jun 21.

Cancer Research Center, Faculty of Medicine, Shahid Beheshti Univeristy of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1111/tbj.13942DOI Listing

Primary breast Anaplasic Lymphoma Kinase-positive anaplastic lymphoma in an adolescent.

Breast J 2020 Jun 21. Epub 2020 Jun 21.

Pathology Department, Faculty of Medicine of Tunis, Salah Azaiez Institute, El Manar University, Tunis, Tunisia.

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http://dx.doi.org/10.1111/tbj.13949DOI Listing
June 2020
1.433 Impact Factor

The emerging role of pectoral nerve block (PECS block) in breast surgery: A case-matched analysis.

Breast J 2020 Jun 21. Epub 2020 Jun 21.

Department of Medical, Surgical and Experimental Sciences, Unit of General Surgery 2, University of Sassari, Sassari, Italy.

To evaluate the benefits of pectoral nerve block (PECS block) in breast cancer surgery, we compared outcomes of 100 patients receiving PECS vs 107 without PECS. Intraoperative use of fentanyl (P < .001) acetaminophen (P = . Read More

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http://dx.doi.org/10.1111/tbj.13939DOI Listing

Idiopathic granulomatous mastitis with erythema nodosum: Is it a variant of clinical presentation indicating treatment resistance? A retrospective cohort study.

Breast J 2020 Jun 19. Epub 2020 Jun 19.

Breast and Endocrine Surgery Unit, SB Marmara University Pendik Training & Research Hospital, Istanbul, Turkey.

Idiopathic granulomatous mastitis (IGM) rarely occurs with erythema nodosum (EN) as a systemic finding. However, the impact of their coexistence on disease severity and response to steroids has not been investigated yet. Patients diagnosed with IGM between September 2014 and October 2018 were divided into two groups according to the presence or absence of EN during the first admission retrospectively. Read More

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http://dx.doi.org/10.1111/tbj.13944DOI Listing

Epithelioid hemangioma of breast mimicking malignancy: One trap during rapid frozen pathologic diagnosis.

Breast J 2020 Jun 19. Epub 2020 Jun 19.

Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

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http://dx.doi.org/10.1111/tbj.13948DOI Listing

Management of recurrent bilateral multifocal pseudoangiomatous stromal hyperplasia (PASH).

Breast J 2020 Jun 19. Epub 2020 Jun 19.

Section of Plastic and Reconstructive Surgery, Department of Surgery, Yale University School of Medicine, New Haven, CT, USA.

Pseudoangiomatous stromal hyperplasia (PASH) is a benign hyperplastic condition of the breast that can lead to macromastia. The standard treatment for PASH is focal excision or rarely reduction mammoplasty. We present a rare case of postpartum bilateral rapid breast enlargement and axillary growth that was refractory to reduction mammoplasty. Read More

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http://dx.doi.org/10.1111/tbj.13950DOI Listing

AJCC 8 edition-A step forward.

Breast J 2020 Jun 18. Epub 2020 Jun 18.

Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1111/tbj.13907DOI Listing

Smoke evacuation in endoscopic breast surgery can enhance operative visualization and respect surgical safety.

Breast J 2020 Jun 17. Epub 2020 Jun 17.

Division of Surgery, Sengkang General Hospital, Singapore.

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http://dx.doi.org/10.1111/tbj.13941DOI Listing

Breast manifestations of type I diabetes mellitus.

Breast J 2020 Jun 18. Epub 2020 Jun 18.

Department of Surgical oncology, Sacred Heart Hospital, Beirut, Lebanon.

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http://dx.doi.org/10.1111/tbj.13938DOI Listing

Tumoural pseudoangiomatous stromal hyperplasia and angiomatosis of the breast in the same tumour: An unprecedented association.

Authors:
Juan B Laforga

Breast J 2020 Jun 17. Epub 2020 Jun 17.

Pathologist, Servicio de Patología, Hospital de Denia, Denia, Spain.

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http://dx.doi.org/10.1111/tbj.13932DOI Listing

Breast unit Efficacy with the relocation of the surgical breast team during the COVID-19 pandemic.

Breast J 2020 Jun 16. Epub 2020 Jun 16.

Breast Surgery Unit, Department of Oncology, Bellaria Hospital "Carlo Alberto Pizzardi", Bologna, Italy.

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http://dx.doi.org/10.1111/tbj.13934DOI Listing

Poikilodermatous breast skin: indicator of an underlying sinister pathology.

Breast J 2020 Jun 16. Epub 2020 Jun 16.

Department of Dermatology, Venereology and Leprosy, King George's Medical University, Lucknow, India.

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http://dx.doi.org/10.1111/tbj.13933DOI Listing
June 2020
1.433 Impact Factor

Orbital metastasis in a male patient after seven years from breast cancer diagnosis.

Breast J 2020 Jun 15. Epub 2020 Jun 15.

Department of Ophthalmology, Humanitas Research Hospital - IRCCS, Rozzano/Milano, Italy.

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http://dx.doi.org/10.1111/tbj.13937DOI Listing

Delayed onset radiation-induced brachial plexopathy.

Breast J 2020 Jun 14. Epub 2020 Jun 14.

Department of Medical Oncology, Cork University Hospital, Co Cork, Ireland.

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http://dx.doi.org/10.1111/tbj.13927DOI Listing

Unicentric castleman's disease of interpectoral (rotter's) lymph nodes mimicking a breast tumor.

Breast J 2020 Jun 14. Epub 2020 Jun 14.

Breast Cancer Surgery Unit, Army General Hospital, Athens, Greece.

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http://dx.doi.org/10.1111/tbj.13929DOI Listing

Patients with psychiatric illness report worse patient-reported outcomes and receive lower rates of autologous breast reconstruction.

Breast J 2020 Jun 11. Epub 2020 Jun 11.

Division of Plastic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, CT, USA.

Psychiatric well-being impacts on general satisfaction and quality of life. This study explored how the presence of psychiatric diagnoses affects patient-reported outcomes in breast reconstruction and on selection of reconstructive modality. Patients who received breast reconstruction at a tertiary hospital between 2013 and 2018 and completed the BREAST-Q survey were included. Read More

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http://dx.doi.org/10.1111/tbj.13936DOI Listing

Autologous fat grafting efficacy in treating PostMastectomy pain syndrome: A prospective multicenter trial of two Senonetwork Italia breast centers.

Breast J 2020 Jun 10. Epub 2020 Jun 10.

Plastic Surgery Unit, Department of Medical Biotechnology and Translational Medicine BIOMETRA, Humanitas Clinical and Research Hospital, Reconstructive and Aesthetic Plastic Surgery School, University of Milan, Milan, Italy.

Postmastectomy pain syndrome (PMPS) represents a common complication following breast surgery defined as a chronic neuropathic pain located in the front of the chest, in the axilla and in the upper arm that for more than 3 months after surgery. Several medications prove to be ineffective while autologous fat grafting revealed to be an innovative solution in the treatment of neuropathic pain syndromes based on retrospective studies. For this reason, we performed a prospective multicenter trial to reduce the memory bias and further increase the evidence of the results. Read More

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http://dx.doi.org/10.1111/tbj.13923DOI Listing

Outcome of CT staging prior to neo-adjuvant chemotherapy in patients with early breast cancer.

Breast J 2020 Jun 10. Epub 2020 Jun 10.

Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.

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http://dx.doi.org/10.1111/tbj.13931DOI Listing

Male bilateral risk-reducing mastectomy: Report of a case.

Breast J 2020 Jun 9. Epub 2020 Jun 9.

Division of Breast Surgical Oncology, Department of Medical and Surgical, Maternal-Infantile and Adult Sciences, University Hospital of Modena, Modena, Italy.

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http://dx.doi.org/10.1111/tbj.13928DOI Listing

Drain secretion and seroma formation after immediate breast reconstruction with a biological and a synthetic mesh, respectively: A randomized controlled study.

Breast J 2020 Jun 9. Epub 2020 Jun 9.

Department of Clinical Sciences, Plastic and Reconstructive Surgery, The Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.

The aim of this study was to compare seroma production in breast reconstruction with a biological mesh with that of a synthetic mesh, in the same patient. The patients were randomized to biological mesh in one breast and synthetical in the other. Twenty-four breasts were included. Read More

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http://dx.doi.org/10.1111/tbj.13921DOI Listing

Male granulomatous mastitis with hidradenitis suppurativa, a rarely encountered disorder.

Breast J 2020 Jun 9. Epub 2020 Jun 9.

Department of Breast Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

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http://dx.doi.org/10.1111/tbj.13899DOI Listing

Feasibility and surgical impact of Z0011 trial criteria in a single-Institution practice.

Breast J 2020 Jun 7. Epub 2020 Jun 7.

Division of Breast Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy.

The purpose of this study is the evaluation of clinical and surgical impact of the Z0011 trial criteria on the management of breast cancer (BC) patients undergoing breast conservative surgery (BCS) at the European Institute of Oncology (IEO). We studied 1386 patients who underwent BCS and sentinel lymph node biopsy (SLNB) from July 2016 to July 2018. Clinical evaluation, breast ultrasound, mammogram, and cyto/histological examination were performed for all patients at the time of diagnosis. Read More

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http://dx.doi.org/10.1111/tbj.13851DOI Listing

Non-invasive lobular neoplasia of the breast: Morphologic features, clinical presentation, and management dilemmas.

Breast J 2020 Jun 4;26(6):1148-1155. Epub 2020 Jun 4.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.

The designation of noninvasive lobular neoplasia applies to atypical epithelial proliferations composed of noncohesive cells secondary to loss or functional alteration of E-cadherin-mediated cell adhesion. The morphologic spectrum of noninvasive lobular neoplasia encompasses atypical lobular hyperplasia (ALH) and classic lobular carcinoma in situ (classic LCIS) and two LCIS variants, namely florid LCIS (F-LCIS) and pleomorphic LCIS (P-LCIS), as defined in the World Health Organization (WHO) Classification of Tumors of the Breast 5th ed. Herein, we review the morphologic, immunohistochemical, and molecular features of noninvasive lobular neoplasia, with special emphasis on F-LCIS and P-LCIS. Read More

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http://dx.doi.org/10.1111/tbj.13857DOI Listing

Perception of pain and influences on opioid use in implant-based breast reconstruction patients.

Breast J 2020 Jun 4. Epub 2020 Jun 4.

Department of Plastic Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.

Although there has been a recent focus on decreasing opioid prescribing through alternative pain medication protocols, the patient's perception of pain related to breast reconstructive surgeries has not been well described. We sought to evaluate patient perception of pain control as it influences opioid use. We hypothesize that modifiable factors may influence patterns in pain perception and postoperative opioid use. Read More

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http://dx.doi.org/10.1111/tbj.13881DOI Listing

Clinical outcome and toxicity from taxanes in breast cancer patients with BRCA1 and BRCA2 pathogenic germline mutations.

Breast J 2020 Jun 4. Epub 2020 Jun 4.

Breast Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

Germline variations in genes coding for proteins involved in the oxidative stress and DNA repair greatly influence drug response and toxicity. Because BRCA1 and BRCA2 proteins play a role in DNA damage repair, we postulated that taxane-related toxicity is potentially higher and clinical outcome in different in patients with BRCA pathogenic variants (PV). Seven hundred nineteen women who underwent BRCA genetic testing and were treated with taxane-containing chemotherapy for early-stage breast cancer between 1997 and 2018 were included in the study. Read More

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http://dx.doi.org/10.1111/tbj.13922DOI Listing

The influence of comorbidity on treatment and survival of triple-negative breast cancer.

Breast J 2020 Jun 2. Epub 2020 Jun 2.

Sutter Institute for Medical Research, Sacramento, CA, USA.

Concomitant comorbidity is a key factor in treatment decision-making for breast cancer. The aim of this study was to determine how the Charlson Comorbidity Index (CCI) affected treatment and risk of mortality of women with TNBC, the subtype with the poorest prognosis. We accessed 20 177 cases of TNBC from the California Cancer Registry 2000-2015 with documented Charlson Comorbidity Index (CCI). Read More

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http://dx.doi.org/10.1111/tbj.13924DOI Listing

Management of breast cancer during COVID-19 pandemic in Morocco.

Breast J 2020 May 30. Epub 2020 May 30.

Department of Radiotherapy, National Institute of Oncology, Mohammed V University, Rabat, Morocco.

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http://dx.doi.org/10.1111/tbj.13925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300778PMC

Management of breast cancer in an EUSOMA-accredited Breast Unit in Lombardy, Italy, during the COVID-19 pandemic.

Breast J 2020 May 30. Epub 2020 May 30.

Laboratory of Nanomedicine and Molecular Imaging, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.

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http://dx.doi.org/10.1111/tbj.13926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300903PMC

Breast metastasis as the initial presentation of malignant pleural mesothelioma.

Breast J 2020 May 30. Epub 2020 May 30.

Clinical Department of Pathology and Cytology, University Hospital Centre Zagreb, Zagreb, Croatia.

Metastatic involvement of the breast is far less common than primary breast carcinoma, comprising 0.5%-6.6% of all breast malignancies. Read More

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http://dx.doi.org/10.1111/tbj.13898DOI Listing