486 results match your criteria Breast Dis[Journal]


Paget disease of the breast: A national retrospective analysis of the US population.

Breast Dis 2020 May 6. Epub 2020 May 6.

Division of Plastic Surgery, Mayo Clinic, Jacksonville, FL, USA.

Background: Paget's disease of the breast is rare. The National Cancer Database (NCDB) is one of the largest tumor databases in the United States.

Methods: We queried the NCDB to identify male and female patients with Paget's disease of the breast who were treated from January 1, 2004, through December 31, 2015. Read More

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http://dx.doi.org/10.3233/BD-200439DOI Listing

Evaluation of Tumor infiltrating lymphocytes in breast carcinoma and their correlation with molecular subtypes, tumor grade and stage.

Breast Dis 2020 Apr 9. Epub 2020 Apr 9.

Department of Community Medicine, ESIC Medical College, Faridabad, Haryana, India.

Background: Tumour infiltrating lymphocytes (TILs) exhibit the local immune response directed against tumor growth and metastasis. TILs have emerged as a tool to assess immune-reactivity in various malignancies including colon, ovary, lung, bladder, breast etc as well as independent marker of favourable prognosis in many tumors. TILs in breast cancer (BC) play a role in tumor response to therapy in the adjuvant and neoadjuvant settings, especially in triple-negative cancers. Read More

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http://dx.doi.org/10.3233/BD-200442DOI Listing

An audit of over 1000 breast cancer patients from a tertiary care center of Northern India.

Breast Dis 2020 Apr 9. Epub 2020 Apr 9.

Additional Professor, Department of Radiation Oncology, AIIMS, New Delhi.

Background: Breast cancer is the commonest cancer among women. India along with United States and China collectively account for one third of the global burden. The present study reports the clinico-epidemiological data of our patient population. Read More

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http://dx.doi.org/10.3233/BD-190435DOI Listing

Primary amyloidosis of the breast excised using an oncoplastic reduction approach.

Breast Dis 2020 Apr 9. Epub 2020 Apr 9.

Department of General Surgery, Division of Breast Services, Cleveland Clinic, Cleveland, OH, USA.

We present a case of surgical removal of primary amyloidosis of the breast utilizing an oncoplastic reduction pattern technique. Primary amyloidosis of the breast is a very rare benign disease characterized by accumulation of insoluble amyloid protein. Biopsy is required for definitive diagnosis, and surgical removal of the mass with clear margins is the main treatment for primary amyloidosis. Read More

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http://dx.doi.org/10.3233/BD-190424DOI Listing

Successful management of diffuse bilateral pseudoangiomatous stromal hyperplasia of the mammary glands by reductive mammoplasty.

Breast Dis 2020 Apr 6. Epub 2020 Apr 6.

Intern, King Abdullah University Hospital, Irbid, Jordan.

Pseudoangiomatous stromal hyperplasia (PASH) is a benign breast condition commonly presented as an incidental microscopic finding. However, it can also manifest as a mass-forming lesion (tumorous PASH) or as gigantomastia (diffuse PASH). Most of the previously reported cases are unilateral tumorous PASH treated by mastectomy. Read More

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http://dx.doi.org/10.3233/BD-190428DOI Listing

YouTube: Searching for answers about breast cancer.

Breast Dis 2020 Apr 2. Epub 2020 Apr 2.

Oklahoma State University Center for Health Sciences, US.

Introduction: Breast cancer is the most common cancer in women, affecting approximately 1 in 8 women worldwide. Additionally, it is either the most or second-most lethal cancer depending on ethnicity. Many women and concerned family members turn to the internet for information regarding the signs, symptoms, diagnosis and treatment of this life-altering condition. Read More

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http://dx.doi.org/10.3233/BD-200445DOI Listing

Breast cancer in elderly Korean women: clinicopathological and biological features.

Breast Dis 2020 Apr 2. Epub 2020 Apr 2.

Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea.

Background: With an aging society, Korean women ≥70 years of age are increasingly being diagnosed with breast cancer.

Objective: To investigate the clinicopathological and biological characteristics of breast cancer in elderly Korean women and compare them with breast cancer in elderly (≥70 years) women globally and in Korean women of all ages.

Methods: We retrospectively reviewed the clinicopathological and biological features of breast cancer in elderly Korean women (≥70 years; n = 87) who sought treatment during 2004-2014 from a single institution. Read More

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http://dx.doi.org/10.3233/BD-190422DOI Listing

Brachial plexus schwannoma mimicking advanced breast carcinoma.

Breast Dis 2020 Feb 17. Epub 2020 Feb 17.

Departamento de Patologia, Hospital de Câncer de Barretos, São Paulo, Brazil.

Background: Schwannoma is an extremely rare benign tumour of the peripheral nervous system; its association with breast cancer is sporadic, and its association with the brachial plexus is extremely rare.

Case Description: The authors report a case of a patient with breast cancer associated with nodulation in the left supraclavicular fossa, and due to the clinical and radiological features, it was considered metastatic lymph node disease. The patient underwent neoadjuvant chemotherapy, with partial response of the breast. Read More

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http://dx.doi.org/10.3233/BD-190432DOI Listing
February 2020

Selection of the Bacillus thuringiensis Berliner strain to produce a parasporin with cytotoxic activity against MCF-7 breast cancer cells.

Breast Dis 2020 ;39(1):37-42

Department of Bioscience and Bioinfomatics, Kyushu Institute of Technology (KIT), Iizuka, Fukuoka, Japan.

Background: Bacillus thuringiensis (Bt) is a Gram-positive bacterium that is known worldwide for its entomopathogenic properties. Recent studies indicate that bacteria produces protein inclusions called parasporins (PSs) that have anti-cancer activity against several types of tumor cells.

Objective: The present work aimed to select a Bt strain that produces an active PS against MCF-7 breast cancer cells, and to provide an initial quantification of its toxicity and protein concentration. Read More

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http://dx.doi.org/10.3233/BD-190405DOI Listing
January 2020

Intracystic papillary carcinoma of the male breast: Dilemmas in diagnosis and management.

Breast Dis 2020 Jan 27. Epub 2020 Jan 27.

Department of General Surgery, All India Institute of Medical Sciences, Patna, Bihar, India.

Intracystic papillary carcinoma (IPC) is a rare malignancy of the breast which is usually found in postmenopausal women. It is still rarer in males and may present with signs of a benign cystic lump. It is sub-classified into three equally prevalent groups considering treatment strategies: intracystic papillary carcinoma alone, intracystic papillary carcinoma with ductal carcinoma in-situ, and those with evidence of invasion. Read More

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http://dx.doi.org/10.3233/BD-190421DOI Listing
January 2020

Breast-conserving surgery vs. total mastectomy in patients with triple negative breast cancer in early stages: A propensity score analysis.

Breast Dis 2020 ;39(1):29-35

Department of Medical Oncology, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.

Background: Breast-conserving surgery (BCS) as an alternative to total mastectomy (TM) in patients with early-stage triple-negative breast cancer (TNBC) is not widely spread.

Objective: We aimed to compare the overall survival (OS) and disease-free survival (DFS) between both surgical approaches in early-stage TNBC patients at 10 years.

Methods: We conducted a retrospective cohort study in TNBC female patients with stage I-IIa, treated at a single-center during the period of 2000-2014. Read More

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http://dx.doi.org/10.3233/BD-190391DOI Listing
January 2020

Evaluation of the expression of P16INK4A by immunohistochemistry in post-neoadjuvant chemotherapy hormone receptor negative breast cancer specimens.

Breast Dis 2019 Dec 9. Epub 2019 Dec 9.

A.M. Rywlin, MD Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL, USA.

Background: Hormone-receptor-negative breast carcinoma (HRNBC), including triple-negative and HER-2 amplified tumors, can overexpress P16INK4a with substantial contribution to tumor progression. In nonneoplastic cells, P16INK4a mediates growth arrest and senescence secondary to cytotoxic compounds.

Objective: We assessed the impact of neoadjuvant chemotherapy (NAC) on P16INK4a expression in breast specimens. Read More

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http://dx.doi.org/10.3233/BD-190419DOI Listing
December 2019

Role of androgen and microRNA in triple-negative breast cancer.

Breast Dis 2020 ;39(1):15-27

Department of Biological Sciences, School of Science, The University of Jordan, Amman, Jordan.

Breast cancer (BC) is the most frequent type of malignancy affecting females worldwide. Molecular-based studies resulted in an identification of at least four subtypes of breast carcinoma, including luminal A and luminal B, Human growth factor receptor (HER-2)-enriched and triple-negative tumors (basal-like and normal breast-like). A proportion of BC cases are of the triple-negative breast cancer (TNBC) type. Read More

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http://dx.doi.org/10.3233/BD-190416DOI Listing
January 2020

Invasive breast carcinoma with hyaline globules ("thanatosomes").

Authors:
Joško Bezić

Breast Dis 2020 ;39(1):43-45

Institute of Pathology, Forensic Medicine and Cytology, Clinical Hospital Center Split, Split, Croatia.

Hyaline globules (thanatosomes) have been observed in many neoplastic and non-neoplastic processes. They represent terminal cytoplasmic structures associated with cytoplasmic blebbing, which are related to cell injury and apoptosis. Thanatosomes are reported rarely in breast tumors. Read More

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http://dx.doi.org/10.3233/BD-190414DOI Listing
January 2020

Role of CD44 in breast cancer.

Breast Dis 2020 ;39(1):1-13

School of Science, The University of Jordan, Amman, Jordan.

Breast cancer (BC) is among the most prevalent type of malignancy affecting females worldwide. BC is classified into different types according to the status of the expression of receptors such as estrogen receptor (ER), human epidermal growth factor receptor 2 (HER2), and progesterone receptor (PR). Androgen receptor (AR) appears to be a promising therapeutic target of BC. Read More

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http://dx.doi.org/10.3233/BD-190409DOI Listing
January 2020
5 Reads

Orbital metastases of invasive lobular breast carcinoma.

Breast Dis 2019 ;38(3-4):85-91

Third Department of Medicine, Oncology Unit, Sotiria General Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Breast cancer is the main site of origin of orbital metastatic disease. Although invasive lobular breast carcinoma accounts for 10-15% of all breast cancer cases, it has been noticed that it metastasizes to the orbit more often compared to breast cancer of no special type (NST). The pathogenesis of this metastasis is not entirely understood; however, it seems that the unique tissue-specific characteristics of orbital microenvironment might contribute to metastatic disease in this particular site. Read More

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http://dx.doi.org/10.3233/BD-190398DOI Listing
March 2020
3 Reads

What you see is not always what you get: Radiographic-pathologic discordance among benign breast masses.

Breast Dis 2019 ;38(3-4):117-123

Division of Plastic and Reconstructive Surgery, St. Joseph's Health Centre, University of Toronto, Toronto, ON, Canada.

The differential diagnosis for benign breast masses is broad and ranges from common lesions like fibroadenomas to rare masses like breast hamartomas. Fibroadenomas are proliferative benign masses made up of fibroglandular tissue. Hamartomas are neoplasms comprised of different tissues that are endogenous to the area where they originate. Read More

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http://dx.doi.org/10.3233/BD-190400DOI Listing
March 2020
2 Reads

IAC standardized reporting of breast fine-needle aspiration cytology, Yokohama 2016: A critical appraisal over a 2 year period.

Breast Dis 2019 ;38(3-4):109-115

Department of Pathology, ESIC Medical College & Hospital, NIT 3, Faridabad, India.

Background: Breast cytology is a significant component of the "Triple approach" for pre-operative diagnosis of breast lumps, the other two being clinical assessment and radiological imaging. The role of Fine needle aspiration cytology (FNAC) as a first line investigation in diagnosing breast lesions is well documented, however histopathology is the gold standard. Cyto-histopathological correlation is of great relevance and also increases precision. Read More

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http://dx.doi.org/10.3233/BD-190393DOI Listing

Inflammatory breast cancer: A review from our experience.

Breast Dis 2019 ;38(2):47-55

Breast Surgery Unit, Aarhus University Hospital, Aarhus, Denmark/Randers Regional Hospital, Randers, Denmark.

Introduction: Inflammatory Breast Cancer (IBC) is a distinct and rare type of breast cancer accounting for up to 6% of all breast cancer cases in Europe. The aim of this study was to investigate diagnostic methods, treatments, and outcome after IBC in patients treated at a single institution in Denmark.

Method: All patients treated for IBC at Aarhus University Hospital between 2000 and 2014 were identified and included in the cohort. Read More

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http://dx.doi.org/10.3233/BD-180365DOI Listing
November 2019
1 Read

Evaluating the incidence of inflammatory breast cancer using population- and hospital-based cancer registries in Casablanca, Morocco.

Breast Dis 2019 ;38(2):39-45

Community Health and Social Medicine Department, CUNY School of Medicine, New York, NY, USA.

Background: Inflammatory breast cancer (IBC) is a rare and aggressive type of breast cancer (BC). Physicians have difficulty diagnosing it correctly given its clinical nature. Previous studies have shown that North Africa compared to the United States has a higher proportion of IBC relative to all BC. Read More

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http://dx.doi.org/10.3233/BD-180357DOI Listing
November 2019
12 Reads

Small breast Schwannoma in an old female; a case report.

Breast Dis 2019 ;38(2):81-83

Surgical Oncology Unit, Oncology Center Mansoura University (OCMU), Mansoura, Egypt.

Schwannoma is a usually benign peripheral nerve sheath tumor with rare breast incidence and few reported cases. We report a case which was presented to and managed in the Oncology center, Mansoura University in November 2017. Read More

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http://dx.doi.org/10.3233/BD-180329DOI Listing
November 2019
1 Read

Infiltration of CD4, CD8, CD56, and Fox-P3-positive lymphocytes in breast carcinoma tissue after neoadjuvant chemotherapy with or without trastuzumab.

Breast Dis 2019 ;38(2):57-65

Department of Surgery, Shiga University of Medical Science, Tsukinowa-cho, Seta, Otsu, Shiga, 520-2192, Japan.

Background: Trastuzumab (Tz) is assumed to prime antibody-dependent cellular cytotoxicity (ADCC); however, it remains unclear whether Tz therapy can clinically induce adaptive cellular immunity.

Objective: Adaptive Cellular Immune Effect of Tz Therapy.

Methods: This study included 29 surgical invasive breast carcinomas administered neoadjuvant chemotherapy with Tz (15 cases) or without Tz (14 cases). Read More

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http://dx.doi.org/10.3233/BD-180350DOI Listing
November 2019
10 Reads

Upstaging papillary lesions to carcinoma on surgical excision is not impacted by patient race.

Breast Dis 2019 ;38(2):67-72

Division of Surgical Pathology, Mercy Hospital and Medical Center, 2525 Michigan Avenue, Chicago, IL, USA.

Background: The management of papillary lesions is controversial with studies showing different rates of upstaging to malignancy. There is a paucity of research into race as an independent risk factor. The aim of this study is to identify if race is correlated with upstaging to malignancy with a secondary focus of analyzing for other personal and tumor specific risk factors for upstaging. Read More

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http://dx.doi.org/10.3233/BD-180379DOI Listing
November 2019
8 Reads

Oncology nurses' knowledge about lymphedema assessment, prevention, and management among women with breast cancer.

Authors:
Loai Abu Sharour

Breast Dis 2019 ;38(3-4):103-108

Faculty of Nursing, AL-Zaytoonah University of Jordan, Amman, Jordan.

Background: Breast cancer-related lymphedema (BCRL) is one of the most common complications among women with breast cancer.

Objective: This study was conducted to evaluate the oncology nurses' knowledge about lymphedema assessment, prevention, and management among women with breast cancer, and identify the relationships between oncology nurses' academic qualification, years of experience, and level of knowledge.

Methods: A cross-sectional descriptive design was used. Read More

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http://dx.doi.org/10.3233/BD-190381DOI Listing
March 2020
2 Reads

WITHDRAWN: Performance of survivin mRNA as a biomarker for breast cancer among Vietnamese women.

Breast Dis 2019 Mar 26. Epub 2019 Mar 26.

Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.

Ahead of Print article withdrawn by publisher. Read More

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http://dx.doi.org/10.3233/BD-180374DOI Listing
March 2019
2 Reads

Inter-laboratory comparison of Ki-67 proliferating index detected by visual assessment and automated digital image analysis.

Breast Dis 2019 ;38(2):73-79

Department of Pathology, General Hospital Slavonski Brod, Croatia.

Background: Proliferation rate is a major determinant of the biologic behavior of the tumor and provides information that can be used to guide treatment decisions.

Methods: This ring study included 27 pathologists from 14 Institutions, in order to assess inter-observer concordance between pathologists in Croatia. We analyzed Ki-67 proliferative index on ten randomly selected breast cancer samples comparing consistency between visual assessment using light microscopy compared to digital image analyses results from one central laboratory as a referral value. Read More

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http://dx.doi.org/10.3233/BD-180341DOI Listing
November 2019
31 Reads

A clinicopathological study of fibroadenomas with epithelial proliferation including lobular carcinoma in-situ, atypical ductal hyperplasia, DCIS and invasive carcinoma.

Breast Dis 2019 ;38(3-4):97-101

Arkadi Rywlin Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami, FL, USA.

Background: Fibroadenoma is a benign mixed tumor composed of epithelial and non-epithelial components. The epithelial component of a fibroadenoma may exhibit proliferation, including lobular carcinoma in-situ, atypical ductal hyperplasia, DCIS and rarely, invasive breast carcinoma.

Objective: In this series of 30 cases of fibroadenoma with epithelial proliferation, we assessed the radiological and histopathological findings of each entity. Read More

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http://dx.doi.org/10.3233/BD-180368DOI Listing
March 2020
25 Reads

A comparative analysis of axillary nodal burden in ultrasound/biopsy positive axilla vs ultrasound negative sentinel lymph node biopsy positive axilla.

Breast Dis 2019 ;38(3-4):93-96

Breast Unit, University Hospital of North Midlands and Keele University, Stoke On Trent, UK.

Background: Axillary Ultrasound (AUS) is now performed as a protocol in every newly diagnosed breast cancer in most European countries. It is an inexpensive and sensitive tool in hands of a trained operator. All AUS negative patients undergo Sentinel Lymph Node Biopsy (SLNB), while AUS positive patients bypass SLNB and undergo axillary nodal clearance (ANC) as a standard protocol. Read More

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http://dx.doi.org/10.3233/BD-160230DOI Listing
March 2020
24 Reads

Metastatic breast cancer to the adductor magnus: A case report and literature overview.

Breast Dis 2019 ;38(1):35-38

University of Illinois, Chicago, USA.

Metastatic breast cancer is commonly found in the pectoralis major and minor muscles, ribs, spine, pelvis, long bones of the extremities, liver, lung, and the brain. It is unusual to see breast cancer metastases to distal skeletal muscle. We report a case of a patient with a history of stage IIA infiltrating lobular carcinoma of the right breast presenting with a metastatic lesion in the right adductor magnus. Read More

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http://dx.doi.org/10.3233/BD-180376DOI Listing
July 2019
3 Reads

Breast cancer section analysis correlates with sentinel lymph node biopsies: Precision and topographic anatomy.

Breast Dis 2019 ;38(1):1-5

Department of 1st Propaedeutic Surgery, University of Athens, Medical School, Hippokratio Hospital, Athens, Greece.

Background: The mainstream treatment of breast cancer is radical mastectomy accompanied with Axillary Lymph Node Dissection (ALND). Lately, more conservative methods accompanied by adjuvant radiotherapy have been gradually replacing radical modalities. The Sentinel Lymph Node Biopsy (SLNB) has been considered such a valuable alternative to surgery conservative approach. Read More

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http://dx.doi.org/10.3233/BD-180355DOI Listing
July 2019
17 Reads

DSCAM-AS1 up-regulation in invasive ductal carcinoma of breast and assessment of its potential as a diagnostic biomarker.

Breast Dis 2019 ;38(1):25-30

Department of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: The long non-coding RNA (lncRNA) DSCAM-AS1 has been demonstrated to participate in the pathogenesis of breast cancer and tamoxifen resistance.

Objective: To evaluate expression profile of DSCAM-AS1 in invasive ductal carcinoma of breast and its suitability as a biomarker for diagnosis of breast cancer.

Methods: We evaluated expression of DSCAM-AS1 in 108 breast tissues including tumoral and adjacent non-cancerous tissues (ANCTs) by means of quantitative real time PCR. Read More

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http://dx.doi.org/10.3233/BD-180351DOI Listing
July 2019
4 Reads

Expression of urokinase plasminogen activator (uPA) in the leukocytes and tissues of patients with benign and malignant breast lesions.

Breast Dis 2019 ;38(1):15-23

Institute of Oncology of Southern Switzerland (IOSI), Breast Unit of Southern Switzerland (CSSI), 6500, Bellinzona, Ticino, Switzerland.

Objective: To show that the expression of urokinase plasminogen activator (uPA) in the leucocytes of patients with benign and malignant breast lesions correlates with its expression in the lesions, and to explore the role of uPA as a tumour marker in breast cancer.

Methods: Using real time reverse transcriptase - polymerase chain reaction (RT-PCR), we examined the expression of uPA in leukocytes and tissues of three groups of women: a) with breast cancer (BC), b) with benign breast lesions and c) a control group of healthy women. An arbitrary value of 1 was assigned to the level of uPA expressed in the leucocytes of the healthy controls; all other measurements were expressed as a function of this value. Read More

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http://dx.doi.org/10.3233/BD-180348DOI Listing
July 2019
4 Reads

Recurrent Mondor's breast disease -- Hormonal contraceptive involvement.

Breast Dis 2019 ;38(1):31-33

Department of Gynecology, Geneva University hospitals (HUG), Switzerland.

Mondor's disease can be a challenging diagnosis. The case we present is of a 29 year-old Brazilian woman, under combined hormonal contraception, who consulted for a painful lump on her right breast. She presented a complete resolution after a local treatment of heparinoid cream and a non-steroidal anti-inflammatory oral treatment, but relapsed 18 months later. Read More

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http://dx.doi.org/10.3233/BD-180346DOI Listing
July 2019
5 Reads

Re-excision rate after sector resection for breast cancer: A 5-year retrospective cohort study.

Breast Dis 2019 ;38(1):7-13

Breast and Endocrine Surgery Unit, Flinders Medical Centre, Adelaide, Australia.

Background: Positive margins after Breast conserving surgery (BCS) for breast cancer can result in local recurrence (LR) requiring further surgery. This can lead to unnecessary patient anxiety, poor prognosis and impose additional economic burden to our health system. The aim of this study is to assess the rate of re-excision for positive margins after BCS using the sector resection technique. Read More

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http://dx.doi.org/10.3233/BD-180339DOI Listing
July 2019
23 Reads

Role of radiotherapy in women over the age of 65 after breast conserving surgery for breast cancer: A 5-year retrospective study.

Breast Dis 2018 ;37(4):197-205

Department of Surgery, Flinders University School of Medicine, Adelaide, SA, Australia.

Background/objective: This study aimed to analyse the local recurrence (LR) and breast cancer related mortality (BCRM) in older women who underwent breast-conserving surgery (BCS) with and without adjuvant radiotherapy (XRT).

Methods: This retrospective study included a total of 299 women who underwent BCS for early breast carcinoma, between the years of 2007 and 2011. Predictive risk factors, local recurrence (LR) and breast cancer related mortality (BCRM) were assessed with a mean follow-up period of 84 months. Read More

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http://dx.doi.org/10.3233/BD-180340DOI Listing
April 2019
14 Reads

Molecular prevalence of human papillomavirus infection among Iranian women with breast cancer.

Breast Dis 2018 ;37(4):207-213

Department of Virology, Iran University of Medical Sciences, Tehran, Iran.

Background: The etiology and molecular mechanisms involved in the development of breast cancer still remain poorly understood. Some epidemiological studies have shown an association between human papillomavirus (HPV) and breast cancer. However, the findings are controversial. Read More

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http://dx.doi.org/10.3233/BD-180333DOI Listing
April 2019
3 Reads

Ductal carcinoma in-situ, cystic hypersecretory type presented by recurrent hemorrhagic cyst.

Breast Dis 2018 ;37(4):225-227

Queen Sirikit Centre for Breast Cancer, Thai Red Cross Society, Bangkok, Thailand.

Recurrent hemorrhagic cyst is an uncommon presentation of breast disease. The ordinary imaging could not demonstrate the malignant features of the cyst. However, the non-contrast dedicated breast computerized tomography could support the malignancy concern. Read More

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http://dx.doi.org/10.3233/BD-180328DOI Listing
April 2019
35 Reads

Prospective comparative study assessing role of ultrasound versus thermography in breast cancer detection.

Breast Dis 2018 ;37(4):191-196

Department of Bio-Medical Engineering, Institute of Electrical Engineering & Information Technology, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran.

Background: The limitations of mammography as a screening and diagnostic tool, especially for younger women with dense breasts, makes it necessary to use an adjunctive modality to cover its shortcomings. Ultrasound and thermography both have potential role in this era.

Objectives: We will compare the accuracy of thermography with ultrasound in breast cancer diagnosis in a clinical setting. Read More

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http://dx.doi.org/10.3233/BD-180321DOI Listing
April 2019
3 Reads

Overall survival of elderly patients with breast cancer is not related to breast-cancer specific survival: A single institution experience in Japan.

Breast Dis 2018 ;37(4):177-183

Background: As the aging population grows, the number of elderly breast cancer patients has rapidly increased especially in Japan; a suitable treatment for elderly patients, considering chronic comorbidities and treatment tolerance, is urgently needed.

Methods: In this retrospective study, 286 elderly breast cancer patients were investigated. Tumor characteristics and survival outcome were compared between 70-79-year-old and ≥ 80-year-old groups. Read More

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http://dx.doi.org/10.3233/BD-170280DOI Listing
April 2019
9 Reads

The relationship between serum E2 levels and recurrence in premenopausal, ER-positive breast cancer patients: A retrospective study.

Breast Dis 2018 ;37(4):185-190

Department of Breast Surgery, The Tazuke Kofukai Medical Research Institute Kitano Hospital, 2-4-20 Ogi-machi Kita-ku Osaka, 530-8480 Japan.

Background: Among estrogens, estradiol (E2) has the strongest physiological activity as a stimulator in estrogen receptor (ER)-positive breast cancer. The aim of this study is to investigate E2 dynamics during endocrine therapy and to explore the optimal environment in which tamoxifen (TAM) exhibits better efficacy for ER-positive premenopausal early breast cancer patients.

Methods: This is a retrospective study enrolled 194 patients with premenopausal ER-positive early-stage breast cancer who aging ≤45 years at onset and receiving luteinizing hormone-releasing hormone-agonist (LHRH-a) and TAM-therapy. Read More

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http://dx.doi.org/10.3233/BD-170307DOI Listing
April 2019
28 Reads

Intracystic breast carcinoma. An important differential diagnosis in postmenopausal patients presenting with a rapidly growing breast cyst. Management and literature review.

Breast Dis 2018 ;37(4):219-224

Intracystic breast carcinoma is a rare clinical entity accounting for 0.5-2% of all breast cancers. It represents a distinctive clinical form rather a histological subtype of breast cancer and can either be in situ or invasive tumor. Read More

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http://dx.doi.org/10.3233/BD-170316DOI Listing
April 2019
8 Reads

Huge mucinous carcinoma of the breast in which doubling time was observed by computed tomography during 3 years without treatment.

Breast Dis 2018 ;37(4):215-218

Department of Surgery, Kashiwara City Municipal Hospital, 1-7-9 Hozenji, Kashiwara City, Osaka 582-0005, Japan.

Here we report the case of a 77-year-old woman with a huge cancer of the right breast for which size was measured on computed tomography in our hospital preoperatively and in other hospital 3 years earlier. During the 3-year untreated interval, the tumor grew from 4 cm to 13 cm in maximum diameter, and the tumor-volume doubling time (TVDT) was calculated as 209 days. The patient underwent mastectomy with axillary lymph node dissection, with the large skin defect covered by autologous skin graft. Read More

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http://dx.doi.org/10.3233/BD-170300DOI Listing
April 2019
12 Reads

Forkhead box M1 (FOXM1) expression predicts disease free survival and may mediate resistance to chemotherapy and hormonotherapy in male breast cancer.

Breast Dis 2018 ;37(3):109-114

Department of Immuno-Histo-Cytology, Salah Azaïz Cancer Institute, Bab Saadoun, 1006 Tunis, Tunisia.

Background: Male breast cancer (MBC) is a rare and neglected disease. Prognostic and predictive factors in MBC are extrapoled from trials conducted on its female counterpart.

Objective: Since the relationship between the transcription factor Forkhead box M1 (FOXM1) expression and the clinical response to chemotherapy and hormonotherapy in MBC remains unknown, we sought to investigate the predictive value of FOXM1 in MBC. Read More

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http://dx.doi.org/10.3233/BD-170315DOI Listing
September 2018
39 Reads

Metaplastic carcinoma of the breast with mesenchymal differentiation (carcinosarcoma). A unique presentation of an aggressive malignancy and literature review.

Breast Dis 2018 ;37(3):169-175

Metaplastic carcinoma of the breast with mesenchymal differentiation (MCMD), previously known as carcinosarcoma, is a very rare and aggressive tumor that has been recently classified as a subtype of metaplastic breast carcinoma. It accounts for 0.08%-0. Read More

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http://dx.doi.org/10.3233/BD-170313DOI Listing
September 2018
42 Reads

Clinico-pathologic disparities of breast cancer in Hispanic/Latina women.

Breast Dis 2018 ;37(3):147-154

Pathology Department, Faculty of Medicine, Benha University, Benha, Egypt.

Background: Breast cancer is the leading cause of cancer death in Hispanic/Latina women nationwide. Limited cancer research has been conducted in this population. El Paso, Texas is a large border city with a population of around 900,000, of which 85% are Latinos and would provide a suitable setting for this study. Read More

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http://dx.doi.org/10.3233/BD-170309DOI Listing
September 2018
21 Reads

Isolated metachronous breast metastasis from renal cell carcinoma: A report of two cases.

Breast Dis 2018 ;37(3):163-167

Metastases to the breast are very uncommon as compared to primary tumours. Breast is an unusual site for metastasis from renal cell carcinoma. Only occasional cases are reported in the literature. Read More

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http://dx.doi.org/10.3233/BD-170294DOI Listing
September 2018
10 Reads

Phyllodes tumors of the breast: clinicopathological analysis of 106 cases from a single institution.

Breast Dis 2018 ;37(3):139-145

Department of pathology, Hassan II university hospital, Fez, Morocco.

Background: Phyllodes tumors (PT) are uncommon biphasic tumors, accounting for less than 1% of all breast primary neoplasms. They form a wide variety of tumors ranging from benign to malignant. Several histological features are used to grade PT into 3 categories: benign (grade I), borderline (grade II) and malignant (grade III) tumors. Read More

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http://dx.doi.org/10.3233/BD-170297DOI Listing
September 2018
17 Reads

Cytological diagnosis of crystallizing galactocele - report of an unusual case.

Breast Dis 2018 ;37(3):159-161

Crystallizing galactocele is a very rare entity which yields a viscous, chalky material on Fine Needle Aspiration Cytology (FNAC). FNAC is used both for diagnosis as well as treatment of this condition. We present here a case of 26 years old lactating female who presented with swelling in the right breast for 8 months. Read More

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http://dx.doi.org/10.3233/BD-170295DOI Listing
September 2018
12 Reads

Primary breast angiosarcoma - a single institution experience from a tertiary cancer center in South India.

Breast Dis 2018 ;37(3):133-138

Department of Pathology, Kidwai Cancer Institute, Bangalore, 560029, India.

Introduction: Primary angiosarcoma of the breast is a rare entity with incidence of less than 0.05% of all malignant breast neoplasms. It occurs in young females without any associated risk factors. Read More

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http://dx.doi.org/10.3233/BD-170291DOI Listing
September 2018
28 Reads