Search Our Scientific Publications & Authors

J Registry Manag 2020 ;47(3):118-121

Objectives: To examine cancer incidence among the 3 Asian, non-Hispanic ethnicities with the highest frequency of cases (South Asian, Chinese, and Vietnamese).

Methods: Age-adjusted incidence rates for all invasive cancers were calculated for South Asian (Indian, Pakistani), Chinese, and Vietnamese cancer cases reported to the Massachusetts Cancer Registry (MCR). Additionally, rates were calculated for the most frequent cancers among non-Hispanic Asians (prostate, colorectal, female breast, female thyroid, lung, and male liver). Read More

Br J Cancer 2021 Jun 14. Epub 2021 Jun 14.

Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.

Background: Mammographic microcalcifications are considered early signs of breast cancer (BC). We examined the association between microcalcification clusters and the risk of overall and subtype-specific BC. Furthermore, we studied how mammographic density (MD) influences the association between microcalcification clusters and BC risk. Read More

Ultrasound Med Biol 2021 Jun 11. Epub 2021 Jun 11.

Department of Pathology, Gaziosmanspasa Education and Research Hospital, Gaziosmanpasa, Istanbul, Turkey.

Our aim was to investigate the correlations between the findings of two-dimensional shear-wave elastography (2D-SWE) and the histopathologic results of microcalcifications (MCs) visualized using ultrasonography (USG). Fifty people with suspicious MCs without accompanying mass were evaluated. They underwent USG and 2D-SWE before USG-guided tru-cut biopsy. Read More

Ann Surg Oncol 2021 Jun 14. Epub 2021 Jun 14.

Division of Surgery, Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Background: Nearly one-third of patients with inflammatory breast cancer (IBC) present with de novo stage IV disease. There are limited data on frequency and clinical outcomes of contralateral axillary metastasis (CAM) in IBC with no consensus diagnostic and treatment guidelines.

Patients And Methods: Frequency of synchronous CAM was calculated in unilateral IBC patients at a single center (10/2004-6/2019). Read More

Front Oncol 2021 28;11:600546. Epub 2021 May 28.

Department of Radiology, Fudan University Shanghai Cancer Center, Shanghai, China.

A limited number of studies have focused on the radiomic analysis of contrast-enhanced mammography (CEM). We aimed to construct several radiomics-based models of CEM for classifying benign and malignant breast lesions. The retrospective, double-center study included women who underwent CEM between November 2013 and February 2020. Read More

Cureus 2021 Jun 8;13(6):e15516. Epub 2021 Jun 8.

Department of Radiology, King Abdulaziz University Hospital, Jeddah, SAU.

Background Neoadjuvant chemotherapy (NAC) is an important step in the treatment of various types of breast cancer by downsizing the tumor to make it operable. Determining disease extent after NAC is essential for accurate surgical planning. MRI has been the gold standard for detecting tumors that are usually difficult to detect on ultrasound or mammography. Read More

Breast Cancer 2021 Jun 13. Epub 2021 Jun 13.

Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, P.O. Box 14155-6117, Tehran, Iran.

Background: Dietary intake of isoflavones has been positively associated with risk of breast cancer (BC) in some earlier studies. In addition, most studies on diet-disease associations came from western countries and limited data are available in the Middle-East.

Methods: This case-control study was performed on 350 women with BC aged over 30 years who were recruited from hospitals or private clinics in Isfahan, Iran. Read More

Breast 2021 Jun 2;59:16-26. Epub 2021 Jun 2.

Department of Translational Medicine, Diagnostic Radiology, Lund University, Skåne University Hospital, 205 02 Malmö, Sweden.

Sweden has a population-based mammography screening programme for women aged 40-74. The objective of this study was to examine the association between mammography screening attendance and sociodemographic factors in 15 of Sweden's 21 health care regions. Register-based information was collected on all mammography screening invitations and attendance during 2017 and 2018, and linked to individual-level sociodemographic data from Statistics Sweden. Read More

Eur Radiol 2021 Jun 12. Epub 2021 Jun 12.

Department of Health Sciences, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.

Objectives: In breast cancer screening, two readers separately examine each woman's mammograms for signs of cancer. We examined whether preventing the two readers from seeing each other's decisions (blinding) affects behaviour and outcomes.

Methods: This cohort study used data from the CO-OPS breast-screening trial (1,119,191 women from 43 screening centres in England) where all discrepant readings were arbitrated. Read More

Lab Invest 2021 Jun 11. Epub 2021 Jun 11.

School of Physics and Astronomy, University of Exeter, Exeter, UK.

Microcalcifications are early markers of breast cancer and can provide valuable prognostic information to support clinical decision-making. Current detection of calcifications in breast tissue is based on X-ray mammography, which involves the use of ionizing radiation with potentially detrimental effects, or MRI scans, which have limited spatial resolution. Additionally, these techniques are not capable of discriminating between microcalcifications from benign and malignant lesions. Read More

PLoS One 2021 11;16(6):e0252476. Epub 2021 Jun 11.

Departments of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Purpose: To investigate the imaging characteristics of early and late recurrent breast cancer and the detectability of mammography, ultrasonography, and breast magnetic resonance imaging (MRI) in patients who underwent breast-conservation therapy (BCT).

Materials And Methods: Total of 1312 women with 2026 surveillance breast MRI after BCT between January 2014 and September 2018 were studied. Early recurrence was defined as newly diagnosed breast cancer and/or axillary metastasis within 12 months of surgery. Read More

Acta Med Litu 2020 23;27(2):61-69. Epub 2020 Dec 23.

Laboratory of Clinical Oncology, National Cancer Institute, Vilnius, Lithuania.

Abstract Background: Breast cancer is the most frequent oncological disease as well as the leading cause of cancer death among women worldwide. Decline in mortality in economically strong countries is observed. This decline is mostly related to early diagnosis (an improvement in breast cancer awareness and the mammography screening program (MSP)) and a more effective treatment. Read More

Eur Radiol 2021 Jun 10. Epub 2021 Jun 10.

Section for Breast Cancer Screening, Cancer Registry of Norway, P.O. Box 5313, 0304, Oslo, Norway.

Objective: To analyze the association between radiologists' performance and image position within a batch in screen reading of mammograms in Norway.

Method: We described true and false positives and true and false negatives by groups of image positions and batch sizes for 2,937,312 screen readings performed from 2012 to 2018. Mixed-effects models were used to obtain adjusted proportions of true and false positive, true and false negative, sensitivity, and specificity for different image positions. Read More

Med Care 2021 Jun 9. Epub 2021 Jun 9.

Faculty of Health Sciences and Social Care, Molde University College Clinic of Surgery, Møre and Romsdal Hospital Trust, Molde Hospital, Molde Section for Cervical Cancer Screening, Cancer Registry of Norway Department of Biostatistics, Oslo Centre for Biostatistics and Epidemiology, University of Oslo Centre for Forensic Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

Background: Many ethnic minority women have low attendance at breast cancer screening.

Objectives: This brief report explores whether women's screening histories impact mammography screening attendance after tailored education.

Research Design: Systematic searches were conducted in 5 databases. Read More

J Cancer Educ 2021 Jun 8. Epub 2021 Jun 8.

Department of Community Health and Social Medicine, School of Medicine, City University of New York, 160 Convent Avenue, New York, NY, 10031, USA.

Most breast cancers in Oman are diagnosed at advanced stages and therefore early detection is important. The Oman Cancer Association (OCA) initiated a mobile mammography program in 2009, but no studies have evaluated its impact. This study aimed at estimating the proportion and predictors of OCA-screened women who had repeated mammography (adherence) and the sensitivity and specificity of the program. Read More

J Surg Case Rep 2021 Jun 4;2021(6):rjab199. Epub 2021 Jun 4.

Department of Breast Oncology, Saitama Medical University International Medical Center, Saitama, Japan.

Granulomatous mastitis is a rare breast disease that is categorized as a benign tumor with chronic inflammation. Since the cause of the chronic inflammation is usually unknown, it is sometimes called idiopathic granulomatous mastitis (IGM). Although imaging modalities, such as ultrasound, magnetic resonance imaging and mammography can detect tumors, they are sometimes unable to differentiate between benign and malignant tumors. Read More

Rev Med Inst Mex Seguro Soc 2020 04 13;58(2):92-99. Epub 2020 Apr 13.

Instituto Mexicano del Seguro Social, Unidad de Medicina Familiar No. 13, Área de Educación. Ciudad de México, México.

Background: In Mexico, breast cancer represents the leading cause of death due to malignant pathology in women, presenting itself at a younger age. Due to an increase in BI-RADS 0 mammograms, the question arises as to what is the incidence of said result in mammograms performed during 2014 and 2017, determine the factors associated with variations in the BI-RADS determination and validate the diagnostic utility of this scale.

Material And Methods: Cross-sectional, comparative, retrospective study. Read More

Radiology 2021 Jun 8:203074. Epub 2021 Jun 8.

From the Departments of Radiology (G.R.K., N.C., S.Y.K., W.K.M.) and Surgery (W.H.), Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea; Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea (G.R.K.); Department of Radiology, Seoul National College of Medicine, Seoul, Republic of Korea (N.C., S.Y.K., W.K.M.); and Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea (N.C., S.Y.K., W.K.M.).

Background There are few interval cancer studies of incident screening MRI for women with a personal history of breast cancer (PHBC). Purpose To evaluate the performance measures of screening breast MRI in women with a PHBC across multiple rounds and to identify subgroups who might be more at risk for interval cancer. Materials and Methods Between January 2008 and March 2019, consecutive screening breast MRI studies for women who had undergone breast-conserving surgery because of breast cancer were retrospectively identified. Read More

Clin Breast Cancer 2021 Jun 4. Epub 2021 Jun 4.

Radiology Department, St. Barts NHS Trust, London, United Kingdom.

Increased breast density is a risk factor for breast cancer and can mask cancer on mammography. This survey attempts to understand clinician views regarding breast density notification in the United Kingdom. Two separate breast density surveys were distributed to radiologists and breast surgeons between May 2019 and May 2020. Read More

Radiol Case Rep 2021 May 28. Epub 2021 May 28.

Department of Radiology, University of Kentucky School of Medicine.

We describe the case of a 64-year-old female with a no relevant medical history. Screening mammography in March 2020 demonstrated calcifications in the right breast, and a diagnostic mammogram was recommended. In the months that followed, the patient experienced tissue changes in the right breast but avoided returning to the facility as the COVID-19 pandemic worsened. Read More

Eur J Radiol 2021 May 23;141:109790. Epub 2021 May 23.

Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77030, United States.

Objectives: To identify associations between baseline ultrasound (US) and mammographic features and metastasis free survival (MFS) in women receiving neo-adjuvant chemotherapy (NACT) for breast cancer.

Methods: The data were collected as part of an ethically approved prospective study. Women with invasive breast cancer receiving NACT who were metastasis free at diagnosis were included. Read More

Gynecol Obstet Fertil Senol 2021 Jun 3. Epub 2021 Jun 3.

Service d'anatomie et cytologie pathologiques, Hôpital Nord Franche-Comté, 100 Route de Moval, 90400 Trévenans, France.

Objectives: Breast cancer is the leading cancer in women worldwide with about 2 million new cases and 685,000 deaths each year. Mammography is the most widely used screening and diagnostic method. Currently, digital technologies advances facilitate the development of connected and portable devices. Read More

J Educ Health Promot 2021 31;10:119. Epub 2021 Mar 31.

Social Determinants of Health Research Center, Health Management and Safety Promotion Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.

Background: Breast cancer is the most common type of cancer among women. Mammography is the most sensitive and important method for screening and early diagnosis of breast cancer. Considering the importance of using mammography in breast cancer screening, this study was performed to evaluate mammographic determinants. Read More

J Educ Health Promot 2021 31;10:102. Epub 2021 Mar 31.

Social Determinants of Health Research Center, Department of Health Promotion and Education, School of Health, Birjand University of Medical Sciences, Birjand, Iran.

Background: Breast cancer is a preventable disease, using three secondary preventive methods of mammography, clinical breast examination (CBE), and breast self-examination (BSE) that can lead to early detection of breast cancer. This study was designed to assess breast cancer screening behavior and its associated factors in females employed in South Khorasan.

Materials And Methods: In this analytic-descriptive study, 2256 female personnel of governmental organizations were investigated in Birjand city in 2016-2017. Read More

Breast Cancer Res Treat 2021 Jun 3. Epub 2021 Jun 3.

Department of Biomedical Data Science, Dartmouth College, 1 Medical Center Drive, HB 7261, Lebanon, NH, 03756, USA.

Purpose: Obesity associated fat infiltration of organ systems is accompanied by organ dysfunction and poor cancer outcomes. Obese women demonstrate variable degrees of fat infiltration of axillary lymph nodes (LNs), and they are at increased risk for node-positive breast cancer. However, the relationship between enlarged axillary nodes and axillary metastases has not been investigated. Read More

Health Promot J Austr 2021 Jun 3. Epub 2021 Jun 3.

Population Health, Sydney Local Health District, Forest Lodge, NSW, Australia.

Background: There are persistent disparities in breast screening participation rates between Australian-born women and women from culturally and linguistically diverse (CALD) backgrounds. Cancer Institute NSW statistics from 2015 show Korean speaking women had the second lowest breast screening participation rates when compared across all language groups.

Objective: The study aimed to gain a better understanding of the motivators and barriers associated with participation in breast cancer screening among women from a Korean background living in the Sydney metropolitan area. Read More

Front Genet 2021 17;12:628136. Epub 2021 May 17.

College of Information Science and Engineering, Xinjiang University, Urumqi, China.

Mastering the molecular mechanism of breast cancer (BC) can provide an in-depth understanding of BC pathology. This study explored existing technologies for diagnosing BC, such as mammography, ultrasound, magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) and summarized the disadvantages of the existing cancer diagnosis. The purpose of this article is to use gene expression profiles of The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) to classify BC samples and normal samples. Read More

Cancer Epidemiol Biomarkers Prev 2021 Jun 2. Epub 2021 Jun 2.

Cancer Prevention and Control, Department of Oncology, Georgetown University Medical Center

Background: Previous reports suggested risk of death and breast cancer varied by comorbidity and age in older women undergoing mammography. However, impacts of functional limitations remain unclear.

Methods: We used data from 238,849 women in the Breast Cancer Surveillance Consortium-Medicare linked database (1999-2015) who had screening mammogram at ages 66-94 years. Read More

J Pathol Clin Res 2021 Jun 2. Epub 2021 Jun 2.

Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, University of Bergen, Bergen, Norway.

The tumor microenvironment plays a critical role in breast cancer progression. Here, we investigated tumor-infiltrating lymphocytes (TILs) and associations with macrophage numbers, tumor stromal elastosis, vascular invasion, and tumor detection mode. We performed a population-based retrospective study using data from The Norwegian Breast Cancer Screening Program in Vestfold County (2004-2009), including 200 screen-detected and 82 interval cancers. Read More

Radiol Phys Technol 2021 Jun 2. Epub 2021 Jun 2.

Medical Image Optimization and Perception Group (MIOPeG), Faculty of Medicine and Health, The University of Sydney, Campus C4 75 East Street, Sydney, NSW 2141, Australia.

Radiomic features from mammograms have been shown to predict breast cancer (BC) risk; however, their contribution to BC characteristics has not yet been explored. This study included 184 women with BC between January 2012 and April 2017. A set of 33 global radiomic features were extracted from the ipsilateral breast mammogram. Read More