Myostatin promotes distinct responses on protein metabolism of skeletal and cardiac muscle fibers of rodents.
Braz J Med Biol Res 2017 Oct 19;50(12):e6733. Epub 2017 Oct 19.
Departamento de Fisiologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil.
Myostatin is a novel negative regulator of skeletal muscle mass. Myostatin expression is also found in heart in a much less extent, but it can be upregulated in pathological conditions, such as heart failure. Myostatin may be involved in inhibiting protein synthesis and/or increasing protein degradation in skeletal and cardiac muscles. Read More