Association between polymorphisms in the APOB gene and hyperlipidemia in the Chinese Yugur population.
Braz J Med Biol Res 2017 Sep 12;50(11):e6613. Epub 2017 Sep 12.
The Institute of Minority Physique and Health, Medical College of Northwest University for Nationalities, Lanzhou, China.
We investigated the influence of apolipoprotein B gene (APOB) variants on the risk of hyperlipidemia (HL) in 631 middle-aged and elderly members of the Chinese Yugur population (HL, n=336; normolipidemia, n=295). APOB polymorphisms were identified using mass spectrometry, and five single nucleotide polymorphisms (rs1042034, rs2163204, rs512535, rs676210, and rs679899) and serum lipids were further analyzed. rs1042034 and rs676210 were significantly associated with HL (P<0. Read More