41,225 results match your criteria Brazilian Journal of Medical and Biological Research [Journal]


Socioeconomic differences among resident, users and neighbour populations of a protected area in the Brazilian dry forest.

J Environ Manage 2018 Dec 3;232:607-614. Epub 2018 Dec 3.

Departamento de Biociências, Universidade Federal Rural do Semiárido, Av. Francisco Mota, 572, Mossoró, Rio Grande do Norte, Brazil. Electronic address:

Protected areas are an important strategy to safeguard biodiversity. However, if social development is not considered, biological conservation targets may not be achieved. In this empirical study, we assess the relationship between poverty and conservation goals in dry forests within a 62,000-ha Brazilian National Park (Caatinga biome). Read More

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December 2018
1 Read

Stepping into a dangerous quagmire: Macroecological determinants of Bothrops envenomings, Brazilian Amazon.

PLoS One 2018 6;13(12):e0208532. Epub 2018 Dec 6.

Escola Superior de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Brazil.

Despite significant and successful efforts in Brazil regarding snakebites in the areas of research, antivenom manufacture and quality control, training of health professionals in the diagnosis and clinical management of bites, little is known about determinants of snakebites incidence in order to further plan interventions to reduce the impact of this medical condition. Understanding the complexity of ecological interactions in a geographical region is important for prediction, prevention and control measures of snakebites. This investigation aims to describe spatial distribution and identify environmental determinants of human envenoming by lancehead pit vipers (Bothrops genus), in the Brazilian Amazon. Read More

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December 2018

Location of water in fresh sugarcane bagasse observed by synchrotron X-ray microtomography.

PLoS One 2018 6;13(12):e0208219. Epub 2018 Dec 6.

Brazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, SP, Brazil.

Sugarcane bagasse is a vast lignocellulosic byproduct generated in the industry with ~50% humidity (1 kg dry matter associated with 1 kg water). Although the presence of water brings deleterious consequences for combustion, storage and sugar extraction, the location of water in fresh bagasse remains unknown. In this work, we use synchrotron X-ray microtomography for non-invasive 3D imaging of fresh bagasse particles, which allows the visualization of intraparticle water. Read More

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December 2018

Letter to The Editor: Access to Opioids, A Global Challenge - Impressions of The Brazilian Scenario.

Authors:
Carolina Neiva

Acta Med Port 2018 Nov 30;31(11):698. Epub 2018 Nov 30.

Serviço de Cuidados Paliativos. Instituto de Assistência ao Servidor Público Estadual. São Paulo. Brazil.

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November 2018
2 Reads

Docosahexaenoic acid promotes cell cycle arrest and decreases proliferation through WNT/β-catenin modulation in colorectal cancer cells exposed to γ-radiation.

Biofactors 2018 Dec 6. Epub 2018 Dec 6.

Cellular and Molecular Oncobiology Program, Brazilian National Cancer Institute, Rio de Janeiro, RJ, Brazil.

The effects of radiation are known to be potentiated by N-3 polyunsaturated fatty acids, which modulate several signaling pathways, but the molecular mechanisms through which these fatty acids enhance the anticancer effects of irradiation in colorectal cancer (CRC) treatment remain poorly elucidated. Here, we aimed to ascertain whether the fatty acid docosahexaenoic acid (DHA) exerts a modulating effect on the response elicited by radiation treatment (RT). Two CRC cell lines, Caco-2 and HT-29, were exposed to RT, DHA, or both (DHA + RT) for various times, and then cell viability, proliferation, and clonogenicity were assessed. Read More

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December 2018

CYP1B1 Gene and Phenotypic Correlation in Patients from Northeastern Brazil with Primary Congenital Glaucoma.

J Glaucoma 2018 Dec 5. Epub 2018 Dec 5.

Hospital das Clínicas, Federal University of Pernambuco (HC - UFPE), Recife, Pernambuco, Brazil.

Purpose: To identify variants in the CYP1B1 gene in northeastern Brazilian patients with PCG and possible genotype-phenotype correlations.

Materials And Methods: This is a cross-sectional observational study of 17 non-related patients with PCG, performed at the Altino Ventura Foundation, Recife, Brazil, between December 2017 and February 2018. All patients underwent an examination, including gathering information from their medical records, slit lamp examination, fundoscopy, tonography, and measuring corneal diameter and thickness. Read More

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December 2018

Evaluation of triage quality in the emergency department: a scoping review protocol.

JBI Database System Rev Implement Rep 2018 Dec 4. Epub 2018 Dec 4.

School of Nursing, University of São Paulo, São Paulo, Brazil.

Review Questions: The objective of this scoping review is to explore the existing literature on the evaluation of the quality of triage for patients of all ages and medical conditions in emergency departments (ED).The question for this review is: How is triage in ED evaluated? More specifically, we are interested in answering the following sub-questions. Read More

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December 2018

Why pesticides with mutagenic, carcinogenic and reproductive risks are registered in Brazil.

Dev World Bioeth 2018 Dec 6. Epub 2018 Dec 6.

Brazil is the biggest market for pesticides in the world. In the registration process, a pesticide must be authorized by the Institute of the Environment, Health Surveillance Agency and Ministry of Agriculture. Evaluations follow a package of toxicological studies submitted by the companies and also based on the Brazilian law regarding pesticides. Read More

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December 2018

Visceral adiposity index is a better predictor of unhealthy metabolic phenotype than traditional adiposity measures: results from a population-based study.

Public Health Nutr 2018 Dec 6:1-10. Epub 2018 Dec 6.

2Department of Nutrition and Health,Universidade Federal de Viçosa,Viçosa, MG,Brazil.

Objective: The present study aimed to investigate whether the visceral adiposity index (VAI) is an effective predictor to identify unhealthy metabolic phenotype by comparing normal-weight and overweight individuals.

Design: A population-based cross-sectional study. Data were collected by interviews, anthropometric evaluation, dietetic, clinical and laboratory tests. Read More

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December 2018
2 Reads

Follicular Development and Reproductive Characteristics in Four Species of Brazilian Tropidurus Lizards.

Zoolog Sci 2018 Dec;35(6):553-563

4 Biology Institute, State University of Campinas. Monteiro Lobato st., 255 - Cidade Universitária, Campinas, São Paulo 13083-862, Brazil.

The follicular development and reproductive characteristics of four species of oviparous lizards in the Tropidurus torquatus group were anatomically and histologically evaluated. We measured specimens, recorded the number of follicles and eggs, and removed the right ovary of each individual, which we processed according to histological routine and photo-documented. For all species, ovaries were divided into a cortical germinal bed, where oogonia and stage I oocytes are located, and a medullar stroma, where the remaining follicular developmental stages occur. Read More

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December 2018

Passalidae (Coleoptera: Scarabaeoidea) from the West-Most Brazilian Amazon Region: Checklist, New Records, and Identification Key.

Neotrop Entomol 2018 Dec 5. Epub 2018 Dec 5.

Coordenação de Biodiversidade, Lab de Sistemática e Ecologia de Coleoptera, Instituto Nacional de Pesquisas da Amazônia, Av. André Araújo, N° 2936, campus II, caixa postal 478, CEP 69011-970, Aleixo Manaus, Amazonas, Brasil.

We present a list of Passalidae species found in the westmost Brazilian Amazon region, which is considered to be a diversity-rich area due to being a tectonic and geographic transition zone in relation to Brazilian Amazon lowlands and the Andean range. The specimens acquired in field collections and museums were analyzed. Their geographical distributions were estimated based on data from labeled specimens and the literature. Read More

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December 2018

Transition to parenthood and mental health at 30 years: a prospective comparison of mothers and fathers in a large Brazilian birth cohort.

Arch Womens Ment Health 2018 Dec 6. Epub 2018 Dec 6.

Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.

Parenthood represents a major biological, social and environmental life change. Mental health disorders are common in parents and impact both the parent and their offspring. However, the relationship between parenthood and mental health and the direction of these effects are poorly understood. Read More

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December 2018
1 Read

Sustainability indicators for bioenergy generation from Amazon׳s non-woody native biomass sources.

Data Brief 2018 Dec 14;21:1900-1908. Epub 2018 Nov 14.

Graduate Program in Health Promotion, Human Development, and Society, Universidade Luterana do Brasil, Canoas, Rio Grande do Sul, Brazil.

This data article focuses on sustainability indicators for bioenergy generation from Brazilian Amazon׳s non-woody native biomass sources, considered to be modern forms of biomass. In the construction of the indicators, the Indicator-based Framework for Evaluation of Natural Resource Management Systems (MESMIS, from the original Spanish) method was used, with the application of the seven sustainability attributes to identify critical points and limiting and favorable factors for sustainability. The data yielded a list of 29 indicators distributed across 27 critical points, selected from three system evaluation areas: 11 environmental indicators, 11 social indicators, and 7 economic indicators. Read More

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December 2018

Paternity analysis, pollen flow, and spatial genetic structure of a natural population of in the Brazilian Amazon.

Ecol Evol 2018 Nov 31;8(22):11143-11157. Epub 2018 Oct 31.

Departamento de Ciências Florestais Escola Superior de Agricultura "Luiz de Queiroz"/Universidade de São Paulo (ESALQ/USP) Piracicaba SP Brazil.

, known as açaí do Amazonas, is a regionally important palm of the Amazon rainforest for the fruit production through extractive agriculture. Little information is available with regard to genetic diversity, gene flow, and spatial genetic structure (SGS) of açaí populations, which are essential for the use, management, and conservation of genetic resources of the species. This research aimed to assess the genetic diversity, inbreeding level, SGS, and gene flow in four ontogenetic stages of a natural population in the Brazilian Amazon, based on 18 microsatellite loci. Read More

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November 2018
1 Read

Deep sequencing analysis of toad skin glands and partial biochemical characterization of its cutaneous secretion.

J Venom Anim Toxins Incl Trop Dis 2018 29;24:36. Epub 2018 Nov 29.

2Laboratory of genetics - LABGEN, Institute of Genetics and Biochemistry, Campus Umuarama, Federal University of Uberlândia, Avenida Pará, Uberlândia, MG 1720 Brazil.

Background: Animal poisons and venoms are sources of biomolecules naturally selected. toads are widespread in the whole Brazilian territory and they have poison glands and mucous gland. Recently, protein from toads' secretion has gaining attention. Read More

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November 2018
1 Read

Evaluation of sexual function in Brazilian women with and without chronic pelvic pain.

J Pain Res 2018 8;11:2761-2767. Epub 2018 Nov 8.

Department of Gynecology and Obstetrics, Federal University of Goiás, Goiânia, Goiás, Brazil,

Purpose: The aim of this study was to evaluate sexual function in women with chronic pelvic pain (CPP) compared to a control group without CPP and to investigate the factors associated with sexual dysfunction in women with CPP.

Methods: This cross-sectional study included 100 women with CPP and 100 controls. Sexual function was evaluated using the Female Sexual Function Index (FSFI) and depression and anxiety using the Hospital Anxiety and Depression Scale (HADS). Read More

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November 2018

Review for Analytical Methods for the Determination of Sodium Cephalothin.

Crit Rev Anal Chem 2018 Dec 5:1-8. Epub 2018 Dec 5.

a School of Pharmaceutical Sciences , São Paulo State University (UNESP) , Araraquara , São Paulo , Brazil.

Infections are the second leading cause of global morbidity and mortality, therefore it is highly important to study the antimicrobial agents such as cephalosporins. Cephalothin, an antimicrobial agent that belongs to the class of cephalosporins, has bactericidal activity and it is widely used in the Brazilian health system. In literature, some analytical methods are found for the identification and quantification of this drug, which are essential for its quality control, which ensures maintaining the product characteristics, therapeutic efficacy and patient's safety. Read More

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December 2018

Sea-level fluctuations and coastal evolution in the state of Rio de Janeiro, southeastern Brazil.

An Acad Bras Cienc 2014 Jun;86(2):671-683

Laboratório de Geologia Costeira, Sedimentologia e Meio Ambiente/LAGECOST, Museu Nacional, Universidade Federal do Rio de Janeiro/ UFRJ, Rio de Janeiro, RJ, Brasil.

The present paper aims to investigate the relative sea-level and the coastal evolution during the Holocene in the Rio de Janeiro coastline, based on geological and biological indicators. Using topographic survey, excavation and coring, and 14C dating of these coastal deposits and beachrocks outcrops, we have reconstructed a sea-level curve for the Holocene. For the first time on the Brazilian coast it was identified a negative record of relative sea-level during Late Pleistocene and Early Holocene transition. Read More

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Polymorphisms in CYP2E1, GSTM1 and GSTT1 and anti-tuberculosis drug-induced hepatotoxicity.

An Acad Bras Cienc 2014 Jun;86(2):855-865

Departamento de Biologia Molecular e Biotecnologia, IB e Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.

Anti-tuberculosis drug-induced hepatitis (ATD- induced hepatitis) has been linked to polymorphisms in genes encoding drug metabolizing enzymes. N-acetyltransferase 2 (NAT2), cytochrome P450 2E1 (CYP2E1) and glutathione S-transferase (loci GSTM1 and GSTT1) are involved in the metabolism of isoniazid, the most toxic drug for the treatment of tuberculosis (TB). This study was designed to determine the frequency and to evaluate whether polymorphisms at CYP2E1, GSTM1 and GSTT1 genes are associated with drug response, as well as to identify clinical risk factors for ATD-induced hepatitis. Read More

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Rheological and some physicochemical characteristics of selected floral honeys from plants of caatinga.

An Acad Bras Cienc 2014 Jun;86(2):981-994

Departamento de Agrotecnologia e Ciências Sociais, Universidade Federal Rural do Semi-Árido/ UFERSA, Mossoró, RN, Brasil.

The aim of this paper was to investigate the physicochemical characteristics and rheological behavior of some floral honeys from species of wild plants found in the Caatinga biome, as well as, correlate honey viscosities with its chemical composition. Thus, five honeys with floral predominance of typical plants foraged by honeybees in Caatinga were analyzed. Results showed that moisture content of honeys ranged from 17. Read More

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June 2014
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Mitochondrial DNA reveals species composition and phylogenetic relationships of hookworms in northeastern Brazil.

Infect Genet Evol 2018 Nov 30. Epub 2018 Nov 30.

Laboratory of Epidemiology and Molecular Systematics, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil; Oswaldo Cruz Foundation, Teresina, Piauí, Brazil. Electronic address:

Hookworm infection persists focally in rural communities in Brazil. In this study, we analyze the mitochondrial nucleotide sequences obtained from hookworms infecting humans in order to characterize species composition and assess their genetic diversity and phylogenetic relationships. Field expeditions and cross-sectional surveys were carried out in three Brazilian municipalities from 2013 to 2017: Nossa Senhora de Nazaré (n = 605) and Teresina (n = 297), in the state of Piauí, and Russas (n = 213) in the State of Ceará. Read More

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November 2018
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Diversification of the widespread Neotropical frog Physalaemus cuvieri in response to Neogene-Quaternary geological events and climate dynamics.

Mol Phylogenet Evol 2018 Nov 30. Epub 2018 Nov 30.

Laboratório de Genética & Biodiversidade, Instituto de Ciências Biológicas, Universidade Federal de Goiás (UFG), Campus Samambaia, 74001-970, Goiânia, Goiás, Brazil. Electronic address:

Here we reconstructed the demographical history and the dispersal dynamics of Physalemus cuvieri through the Neogene-Quaternary periods by coupling DNA regions with different mutation rates, ecological niche modelling, reconstruction of spatio-temporal lineage dispersal and coalescent simulations. Still, to test alternative diversification scenarios we used approximate Bayesian computation. Molecular phylogenetic analysis recovered four deep and strongly supported clades, which we interpret as population lineages. Read More

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November 2018

Molecular types of Cryptococcus species isolated from patients with cryptococcal meningitis in a Brazilian tertiary care hospital.

Braz J Infect Dis 2018 Nov 30. Epub 2018 Nov 30.

Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Unidade de Doenças Infecciosas, Porto Alegre, RS, Brazil. Electronic address:

There are limited data on the molecular epidemiology of cryptococcosis in Brazil. Here, we report on the identification of the molecular pattern of the Cryptococcus species that caused meningitis in patients admitted in a Brazilian reference tertiary care hospital, and review the published studies addressing the molecular epidemiology of Cryptococcus in Brazil. Our study has shown the predominance of molecular type VNII in predominantly HIV-infected patients with meningoencephalitis admitted to a tertiary care hospital in the southern area of Brazil. Read More

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November 2018

Chemical Space and Diversity of NuBBE Database: A Chemoinformatic Characterization.

J Chem Inf Model 2018 Dec 3. Epub 2018 Dec 3.

NuBBEDB is the first library of natural products of Brazilian biodiversity. It includes a large variety of classes of compounds and structural types of secondary metabolites of plants, fungi, insects, marine organisms and bacteria. So far the chemical diversity and complexity of NuBBEDB has not been characterized in a systematic and detailed manner. Read More

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December 2018
3 Reads

Pesticide Exposure Assessment Paradigm for Stingless Bees.

Environ Entomol 2018 Dec 3. Epub 2018 Dec 3.

Federal University of Bahia (UFBA), Salvador, BA, Brazil.

Although the importance of bees as the pollinators responsible for maintaining gene flow for many native and cultivated plants in ecosystems around the world is recognized, much of their biodiversity and behavior remains to be discovered. Stingless bees are considered key pollinators for several plant species in tropical and subtropical ecosystems and they also provide pollination services for economically important agricultural crops. Many countries are using the honey bee (Apis mellifera Linnaeus, 1758, Hymenoptera: Apidae) as a surrogate to evaluate the risk of pesticides to all species of bees. Read More

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December 2018

Cytogenetics of two hylid frogs from Brazilian Cerrado.

Genet Mol Biol 2018 Nov 29. Epub 2018 Nov 29.

Laboratório de Genética & Biodiversidade, Departamento de Genética, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, GO, Brazil.

Cytogenetic data can be useful for taxonomic and phylogenetic studies, as well as to provide information about chromosome evolution. Therefore, it may help design conservation priorities for some threatened species, such as anurans. Herein, we describe the karyotypes of Scinax constrictus and Ololygon centralis, native endemic species from the Brazilian Cerrado. Read More

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November 2018

Lack of association between genetic polymorphisms in IGF1 and IGFBP3 with twin births in a Brazilian population (Cândido Godói, Rio Grande do Sul).

Genet Mol Biol 2018 Nov 29. Epub 2018 Nov 29.

Departmento de Genética, Instituto de Bociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

Insulin-like growth factor (IGF-1) is an important peptide hormone involved in the reproduction and fetal development of mammals, and it is suggested that it may influence the human twinning rate. This study aimed to test such possible association, investigating the genetic polymorphisms IGF1 (CA)n and IGFBP3 rs2854744 in the population from Candido Godoi (CG), a small city located in the South of Brazil that has a high prevalence of twin births. A case-control study was performed comprising a total of 39 cases (representing about 40% of the mothers of twins who were born in CG after 1995) and 214 controls (mothers of non-twin children), 97 of whom were living in CG while 117 were living in Porto Alegre. Read More

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November 2018
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Molecular genotyping of G6PD mutations and Duffy blood group in Afro-descendant communities from Brazilian Amazon.

Genet Mol Biol 2018 Nov 29. Epub 2018 Nov 29.

Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, PA, Brazil.

Glucose-6-phosphate dehydrogenase deficiency (G6PDd) and Duffy-negative blood group are two red blood cells variants that confer protection against malaria. In this study, the distribution of the most common G6PD variants (G6PD*A-, GGPD*A and G6PD Mediterranean) and the major alleles of the Duffy blood group (FY*A, FY*B and FY*BES) were investigated in an Afro-descendant population from state of Pará, Brazilian Amazon. G6PD variants and Duffy blood group alleles were determined by TaqMan SNP genotyping assay. Read More

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November 2018

The pequi pulp oil (Caryocar brasiliense Camb.) provides protection against aging-related anemia, inflammation and oxidative stress in Swiss mice, especially in females.

Genet Mol Biol 2018 Nov 29. Epub 2018 Nov 29.

Departmento de Genética e Morfologia, Instituto de Ciências Biologicas, Universidade de Brasília, Brasilia, DF, Brazil.

Continued exposure to reactive oxygen species and inflammation are the rationale behind aging theories and associated diseases. Scientific evidence corroborates the ethnomedicinal use of the oil of pequi (Caryocar brasiliense Camb.), a typical Brazilian Cerrado fruit, against oxidative damage to biomolecules and inflammation. Read More

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November 2018
5 Reads

Effects of polymorphisms in APOB, APOE, HSD11β1, PLIN4, and ADIPOQ genes on lipid profile and anthropometric variables related to obesity in children and adolescents.

Genet Mol Biol 2018 Nov 23. Epub 2018 Nov 23.

Laboratório de Polimorfismos e Ligação, Departamento de Genética, Universidade Federal do Paraná (UFPR) Curitiba, PR, Brazil.

Genes can influence lipid profile and anthropometric variables related to obesity. The present study aimed to verify if variants of the APOE, APOB, ADIPOQ, HSD11β1, and PLIN4 genes are associated with lipid levels or anthropometric variables in a sample comprised of 393 Euro-Brazilian children and adolescents. DNA was genotyped by TaqMan allelic discrimination assay. Read More

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November 2018
1 Read

Parasitism, sexual dimorphism and effect of host size on Apocephalus attophilus offspring, a parasitoid of the leaf-cutting ant Atta bisphaerica.

PLoS One 2018 3;13(12):e0208253. Epub 2018 Dec 3.

Institute of Biological Sciences, Federal University of Viçosa Campus Florestal, Florestal, Minas Gerais, Brazil.

Atta bisphaerica (Forel) is a leaf-cutting ant that specializes on grass and causes productivity losses in sugar cane fields and pastures. Three phorid species, Apocephalus attophilus (Borgmeier), Myrmosicarius grandicornis (Borgmeier) and Eibesfeldtphora bragancai (Brown), have been found parasitizing A. bisphaerica workers. Read More

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December 2018

Advances in rheumatology practice in Brazil.

Rheumatol Int 2018 Dec 1. Epub 2018 Dec 1.

Laboratório de Investigação em Osteoartropatias, Department of Internal Medicine, Liga de Reumatologia e Doenças Autoimunes, Instituto de Biomedicina, Faculdade de Medicina, Federal University of Ceará, Rua Cel. Nunes de Melo, 1315, 1°. Andar, Rodolfo Teófilo, Fortaleza, CE, 60430-270, Brazil.

Despite resilient inequities, Brazil has seen progressive improvement in health care in the last 25 years. Infectious diseases rendered place to chronic non-communicable diseases as a major cause of death. Existence of traditional schools of medicine and training services in rheumatology helped form a reasonable number of specialists, though irregular distribution due to the economic issues favoring their clustering in major cities. Read More

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December 2018

Screening of plant growth promotion ability among bacteria isolated from field-grown sorghum under different managements in Brazilian drylands.

World J Microbiol Biotechnol 2018 Nov 30;34(12):186. Epub 2018 Nov 30.

Embrapa Semiárido, BR 428, km 152, s/n, Petrolina, PE, Brazil.

Sorghum [Sorghum bicolor (L.) Moench] is a multipurpose grass cultivated in drylands due to its adaptation to drought. However the characteristics of sorghum-associated bacteria are not known in the Brazilian drylands. Read More

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November 2018

Brazilian Analytical Decision Model for Cardiovascular Disease: An Adaptation of the Scottish Cardiovascular Disease Policy Model.

Value Health Reg Issues 2018 Nov 28;17:210-216. Epub 2018 Nov 28.

Health Economics and Health Technology Assessment, Institute of Health and Technology Assessment, University of Glasgow, Glasgow, UK.

Introduction: Despite the significant impact of cardiovascular disease (CVD), there is not yet an analytical decision tool for assessing efficiency of interventions to prevent primary CVD events in Brazil. Therefore, we sought to adapt a Scottish CVD Policy Model to be used in the proposed population.

Methods: Calibration consisted of identifying multiplicative factors for linear predictors of existing survival analysis models to produce predictions that closely match observed data (Life-table and Brazilian cohort study). Read More

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November 2018

Factors associated with mortality in severe community-acquired pneumonia: A multicenter cohort study.

J Crit Care 2018 Nov 22;50:82-86. Epub 2018 Nov 22.

Programa de Pós-Graduação em Clínica Médica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.; Postgraduate Program, Instituto D'Or de Pesquisa e Ensino, Rio de Janeiro, Brazil.

Objective: Describe characteristics and outcomes of CAP admitted to public ICUs in Brazil.

Methods: Retrospective cohort study in 4 Tertiary Public Hospitals in Rio de Janeiro, Brazil during 2016. Patients admitted to ICUs with a diagnosis of community-acquired pneumonia were included. Read More

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November 2018

Cross-cultural adaptation of the Pelvic Girdle Questionnaire (PGQ) into Brazilian Portuguese and clinimetric testing of the PGQ and Roland Morris questionnaire in pregnancy pelvic pain.

Braz J Phys Ther 2018 Nov 17. Epub 2018 Nov 17.

Masters and Doctoral Programs in Physical Therapy, Universidade Cidade de São Paulo (UNICID), São Paulo, SP, Brazil. Electronic address:

Objective: To translate and cross-culturally adapt the Pelvic Girdle Questionnaire (PGQ) into Brazilian Portuguese and test the measurement properties of the PGQ and the Roland Morris Disability Questionnaire (RMDQ) in women with pelvic pain during pregnancy.

Methods: Thirty pregnant women were included in the assessment of the pre-test of the final version of the PGQ and 100 were included in the assessment of the measurement properties. In the initial assessment, the PGQ, RMDQ, pain numerical rating scale, and WHOQOL-BREF were applied to test the internal consistency and construct validity. Read More

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November 2018

The effects of dual task gait and balance training in Parkinson's disease: a systematic review.

Physiother Theory Pract 2018 Dec 3:1-9. Epub 2018 Dec 3.

a Laboratory of Motor Behavior, School of Physical Education and Sport , University of São Paulo , São Paulo , Brazil.

In patients with Parkinson's disease (PD), the ability to perform simultaneous tasks may be impaired. However, there is no consensus as to whether the strategy of use dual task (DT) should be used with PD patients during gait and balance training because DT can increase the risk of falls. Therefore, it is necessary to critically analyze the relevant studies and evaluate the indications for the use of DT and its effects as a therapeutic strategy. Read More

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December 2018

Improving measurement accuracy of Brazilian tensile strength of rock by digital image correlation.

Rev Sci Instrum 2018 Nov;89(11):115107

Petroleum Engineering Department, University of Louisiana at Lafayette, Lafayette, Louisiana 70506, USA.

Since the invention of the Brazilian test about eight decades ago, discussions on the validity of indirect tensile strength measurement by the Brazilian test have always been of focus in rock fracture mechanics. According to the principles of the Brazilian test, experimental data are only valid when a fracture is initiated at/near the disc-shaped planar center and propagates along the diametral loading plane. However, traditional experimental results can only show readers a final failure instead of fracture process. Read More

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November 2018

Chronic pain is associated with increased health care use among community-dwelling older adults in Brazil: the Pain in the Elderly (PAINEL) Study.

Fam Pract 2018 Dec 5. Epub 2018 Dec 5.

Faculty of Medicine, Department of Preventive and Social Medicine, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, Brazil.

Background: Chronic pain is known to increase health care use in high-income countries, but in Brazil, little is known.

Objective: To investigate the association between chronic pain and health care use among Brazilian older adults and explore the relationship between pain severity and health care use.

Methods: This cross-sectional study was derived from the population-based study Frailty in Brazilian Older People-FIBRA. Read More

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December 2018

Guided imagery relaxation therapy on preoperative anxiety: a randomized clinical trial.

Rev Lat Am Enfermagem 2018 Nov 29;26:e3101. Epub 2018 Nov 29.

Universidade Federal do Triângulo Mineiro, Departamento Didático Científico de Enfermagem na Assistência Hospitalar, Uberaba, MG, Brasil.

Objective: to evaluate the effect of relaxation therapy with guided imagery on state anxiety and cortisol in the immediate preoperative period in patients submitted to bariatric surgery by videolaparoscopy.

Method: a randomized, triple-blind clinical trial in a large teaching hospital in the interior of Minas Gerais. Twenty-four patients who would undergo video-laparoscopic bariatric surgery were randomly allocated in two groups, namely 12 in the control group and 12 in the experimental group. Read More

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November 2018
1 Read

Frailty syndrome among elderly and associated factors: comparison of two cities.

Rev Lat Am Enfermagem 2018 Nov 29;26:e3100. Epub 2018 Nov 29.

Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto, SP, Brasil.

Objective: to compare the frailty syndrome among elderly people living at home in two Brazilian cities and to identify factors related to sociodemographic and health-related variables.

Method: population-based cross-sectional study with 480 elderly individuals from the cities of Ribeirão Preto/SP and João Pessoa/PB, with application of the Mini Mental State Examination instruments and the Edmonton Frailty, Geriatric Depression and Lawton and Brody scales. Descriptive analysis, Chi-square test, Fisher's test, Student's t-test, Spermann's correlation and Logistic regression were used. Read More

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November 2018
5 Reads

Clinical trial for the control of water intake of patients undergoing hemodialysis treatment.

Rev Lat Am Enfermagem 2018 Nov 29;26:e3091. Epub 2018 Nov 29.

Universidade de São Paulo, Escola de Enfermagem de Ribeirão Preto, PAHO/WHO Collaborating Centre for Nursing Research Development, Ribeirão Preto, SP, Brazil.

Objective: to analyze the impact of an educational and motivational intervention for patients with a chronic kidney disease, undergoing hemodialysis treatment, on the control of fluid intake during interdialytic periods.

Method: a quasi-experimental, non-randomized clinical trial with patients from a Nephrological Unit of the State of São Paulo. Participants were included in two groups: Control Group with 106 patients and Intervention Group with 86 patients, totaling 192 participants. Read More

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November 2018
1 Read

Randomized clinical study on radial artery compression time after elective coronary angiography.

Rev Lat Am Enfermagem 2018 Nov 29;26:e3084. Epub 2018 Nov 29.

Universidade Federal de São Paulo, Escola Paulista de Enfermagem, São Paulo, SP, Brasil.

Objective: to compare two compression times of the radial artery after coronary angiography with customized compressive dressing regarding the occurrence of hemostasis and vascular complications.

Method: a randomized clinical study was carried out in patients undergoing elective transradial coronary angiography in two study groups: (G30), whose compressive dressing was maintained for 30 minutes, and (G60), whose compressive dressing was maintained for 60 minutes, both until the first evaluation of hemostasis. Variables related to patients, procedure, occurrence of hemostasis, and vascular complications were analyzed. Read More

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November 2018
3 Reads

Gender and generation perspectives in the narratives of sexually abused women in childhood.

Rev Lat Am Enfermagem 2018 Nov 29;26:e3078. Epub 2018 Nov 29.

Universidade de São Paulo, Escola de Enfermagem, São Paulo, SP, Brazil.

Objective: to analyze the narratives of sexually abused women in childhood, identifying issues related to gender and generation.

Method: descriptive research with a qualitative approach, based on 214 reports selected from the Brazilian campaign #primeiroassedio (first harassment), which took place on Twitter social network, collected from a structured instrument. Thematic content analysis was used. Read More

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November 2018
1 Read

Safety of a formulation containing chitosan microparticles with chamomile: blind controlled clinical trial.

Rev Lat Am Enfermagem 2018 Nov 29;26:e3075. Epub 2018 Nov 29.

Universidade de São Paulo, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Ribeirão Preto, SP, Brazil.

Objective: to evaluate the safety of a topical formulation containing chamomile microparticles coated with chitosan in the skin of healthy participants.

Method: phase I blind, controlled, non-randomized, single-dose clinical trial with control for skin, base formulation, and formulation with microparticles. The variables analyzed were irritation and hydration by the Wilcoxon and Kruskall-Wallis tests. Read More

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November 2018
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Type 1 cardiorenal syndrome in a patient with an acute infection caused by Trypanosoma cruzi in the Brazilian Amazon region - a case report.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):869-872

Programa de Pós-Graduação em Medicina Tropical, Universidade do Estado do Amazonas, Manaus, AM, Brasil.

Cardiorenal syndrome type 1 (CRS 1) occurs when acute heart failure leads to acute kidney injury. There are several etiologies of CRS 1, including Chagas disease. Here, we present the first case report of CRS 1 in a patient with acute Chagas disease. Read More

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April 2018
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American cutaneous leishmaniasis in a northeast Brazilian city: clinical and epidemiological features.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):837-842

Faculdade de Medicina, Universidade Federal do Cariri, Barbalha, CE, Brasil.

Introduction: This study characterized the clinico-epidemiological profile of American cutaneous leishmaniasis (ACL) cases in Barbalha, Ceará State, Brazil.

Methods: Medical records of 363 patients visiting Federal University of Cariri between 2009 and 2014 were analyzed.

Results: ACL was more prevalent in men with low education level from rural zones. Read More

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December 2017
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