2,100 results match your criteria Brazilian Journal of Infectious Diseases [Journal]


HLA-B*14 allele predicts HIV-1 mother-to-child-transmission, in Salvador, Brazil.

Braz J Infect Dis 2019 Feb 14. Epub 2019 Feb 14.

Universidade Federal da Bahia, Complexo Hospitalar Prof. Edgard Santos, Laboratório de Pesquisa em Infectologia, Salvador, BA, Brazil; Universidade Federal da Bahia, Complexo Hospitalar Prof. Edgard Santos, Salvador, BA, Brazil; Universidade Federal da Bahia, Bahia, Departamento de Medicina, Salvador, BA, Brazil. Electronic address:

Background: Mother-to-child-transmission (MTCT) is the main route of HIV-1 infection in children. Genetic studies suggest HLA-B alleles play an important role on HIV-1 transmission, progression, and control of HIV-1 infection.

Objective: To evaluate which polymorphisms of HLA-B are involved in HIV-1 MTCT. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183055
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http://dx.doi.org/10.1016/j.bjid.2018.12.002DOI Listing
February 2019
2 Reads

HIV testing and HIV knowledge among men who have sex with men in Natal, Northeast Brazil.

Braz J Infect Dis 2019 Feb 8. Epub 2019 Feb 8.

Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil.

Background: Men who have sex with men (MSM) account for the highest prevalence of HIV in Brazil. HIV testing allows to implement preventive measures, reduces transmission, morbidity, and mortality.

Methods: We conducted a cross-sectional study to evaluate HIV testing during lifetime, factors associated with the decision to test, knowledge about HIV transmission, and use of condoms between MSM from the city of Natal, northeast Brazil. Read More

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http://dx.doi.org/10.1016/j.bjid.2019.01.003DOI Listing
February 2019

Molecular characteristics and virulence gene profiles of Staphylococcus aureus causing bloodstream infection.

Braz J Infect Dis 2018 Nov - Dec;22(6):487-494. Epub 2018 Dec 27.

Wuhan University, Zhongnan Hospital, Department of Laboratory Medicine, Wuhan, China. Electronic address:

Background: The rate of methicillin-resistant Staphylococcus aureus (MRSA) among the total of S. aureus isolates decreased to 35.3% in 2017 in China. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.12.001DOI Listing
December 2018
1 Read

Novel fluoronucleoside analog NCC inhibits lamivudine-resistant hepatitis B virus in a hepatocyte model.

Braz J Infect Dis 2018 Nov - Dec;22(6):477-486. Epub 2018 Dec 23.

Zhengzhou University, Academy of Medical and Pharmaceutical Sciences, Henan Key Laboratory for Pharmacology of Liver Diseases, Zhengzhou, China. Electronic address:

Antiviral drug resistance is the most important factor contributing to treatment failure using nucleos(t)ide analogs such as lamivudine for chronic infection with hepatitis B virus (HBV). Development of a system supporting efficient replication of clinically resistant HBV strains is imperative, and new antiviral drugs are needed urgently to prevent selection of drug-resistant HBV mutants. A novel fluorinated cytidine analog, NCC (N-cyclopropyl-4'-azido-2'-deoxy-2'-fluoro-β-d-cytidine), was recently shown to strongly inhibit human HBV in vitro and in vivo. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.11.005DOI Listing
December 2018
2 Reads

Assessing and screening for T-cell epitopes from Mycobacterium tuberculosis RD2 proteins for the diagnosis of active tuberculosis.

Braz J Infect Dis 2018 Nov - Dec;22(6):462-471. Epub 2018 Dec 5.

Fudan University, Huashan Hospital, Department of Infectious Diseases, Shanghai, China. Electronic address:

The Region of D eletion 2 (RD2) of Mycobacterium tuberculosis encodes reserved antigens that contribute to bacterial virulence. Among these antigens, Rv1983, Rv1986, Rv1987, and Rv1989c have been shown to be immunodominant in infected cattle; however, their diagnostic utility has not been evaluated in humans. In this study, we screened 87 overlapping synthetic peptides encoded by five RD2 proteins for diagnosing tuberculosis epitopes in 50 active tuberculosis (TB) cases, 31 non-tuberculosis patients and 36 healthy individuals. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.10.280DOI Listing
December 2018
1 Read

Human T cell lymphotropic virus type 1 infection among men who have sex with men in Central Brazil.

Braz J Infect Dis 2018 Nov - Dec;22(6):472-476. Epub 2018 Dec 6.

Universidade Federal de Mato Grosso do Sul, Faculdade de Ciências Farmacêuticas, Alimentos e Nutrição, Laboratório de Imunologia Clínica, Mato Grosso do Sul, MS, Brazil; Fundação Oswaldo Cruz, FIOCRUZ, Mato Grosso do Sul, MS, Brazil.

Human T cell lymphotropic virus type 1 (HTLV-1) was the first retrovirus discovered in humans and is endemic in several parts of the world. Because of risk behaviors, mainly sexual, men who have sex with men (MSM) are at high risk of acquiring HTLV-1 infection. A cross-sectional study was performed to estimate the prevalence of HTLV-1 infection, to characterize genetically HTLV-1 sequences and to identify risk behaviors associated with this infection among MSM in Central Brazil. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.11.003DOI Listing
December 2018
1 Read

Epidemiology of pathogens causing urinary tract infections in an urban community in southern Brazil.

Braz J Infect Dis 2018 Nov - Dec;22(6):505-507. Epub 2018 Dec 5.

Universidade Federal do Paraná, Curso de Farmácia, Departamento de Análises Clínicas, Curitiba, PR, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bjid.2018.10.279DOI Listing
December 2018
1 Read

Chronic skull osteomyelitis due to Cryptococcus neoformans: first case report in an HIV-infected patient.

Braz J Infect Dis 2018 Nov - Dec;22(6):499-502. Epub 2018 Dec 6.

Instituto de Infectologia Emilio Ribas, Departamento de Neurologia, São Paulo, SP, Brazil; Universidade de São Paulo, Hospital das Clínicas da Faculdade de Medicina (HCFM-USP), Departamento de Doenças e Infecciosas, São Paulo, SP, Brazil; Universidade de São Paulo, Instituto de Medicina Tropical, Laboratório de Investigação Médica, São Paulo, SP, Brazil.

Osteomyelitis due to Cryptococcus neoformans are described in mostly 10% of patients with disseminated cryptococcosis, being direct inoculation even more uncommon. We report the case of an HIV-infected patient with history of recurring itching on his scalp and repetitive local trauma. For eighteen months, he noticed a painful and slow growing lump on his scalp. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.11.004DOI Listing
December 2018
3 Reads

Measles outbreak in Brazil, 2018.

Braz J Infect Dis 2018 Sep - Oct;22(5):359

Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Unidade de Doenças Infecciosas, Porto Alegre, RS, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bjid.2018.11.001DOI Listing
November 2018
1 Read

Molecular types of Cryptococcus species isolated from patients with cryptococcal meningitis in a Brazilian tertiary care hospital.

Braz J Infect Dis 2018 Nov - Dec;22(6):495-498. Epub 2018 Nov 30.

Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Unidade de Doenças Infecciosas, Porto Alegre, RS, Brazil. Electronic address:

There are limited data on the molecular epidemiology of cryptococcosis in Brazil. Here, we report on the identification of the molecular pattern of the Cryptococcus species that caused meningitis in patients admitted in a Brazilian reference tertiary care hospital, and review the published studies addressing the molecular epidemiology of Cryptococcus in Brazil. Our study has shown the predominance of molecular type VNII in HIV-infected patients with cryptococcal meningoencephalitis. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.11.002DOI Listing
November 2018
2 Reads
1.096 Impact Factor

Clinical management of leprosy patients during the yellow fever outbreak in Brazil.

Braz J Infect Dis 2018 Nov - Dec;22(6):503-504. Epub 2018 Nov 27.

Universidade Federal de São Paulo, Departamento de Psicobiologia, São Paulo, SP, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bjid.2018.07.011DOI Listing
November 2018
1 Read

Assessment of conventional PCR and real-time PCR compared to the gold standard method for screening Streptococcus agalactiae in pregnant women.

Braz J Infect Dis 2018 Nov - Dec;22(6):449-454. Epub 2018 Nov 22.

Universidade de Santa Cruz do Sul (UNISC), Escola de Farmácia, Santa Cruz do Sul, RS, Brazil; Universidade Federal do Pampa (UNIPAMPA), Escola de Medicina, Uruguaiana, RS, Brazil. Electronic address:

Group B Streptococcus is a causative agent of invasive neonatal infections. Maternal colonization by Streptococcus agalactiae is a necessary condition for vertical transmission, with efficient screening of pregnant women playing an essential role in the prevention of neonatal infections. In this study, we aimed to compare the performance of conventional polymerase chain reaction and real-time PCR assays as screening methods for S. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.09.005DOI Listing
November 2018
11 Reads

Time of catheter removal in candidemia and mortality.

Braz J Infect Dis 2018 Nov - Dec;22(6):455-461. Epub 2018 Nov 20.

CTI - Clinical Trial & Consulting, Cincinnati, USA.

Background: The impact of central venous catheter (CVC) removal on the outcome of patients with candidemia is controversial, with studies reporting discrepant results depending on the time of CVC removal (early or any time during the course of candidemia).

Objective: Evaluate the effect of time to CVC removal, early (within 48h from the diagnosis of candidemia) vs. removal at any time during the course of candidemia, on the 30-day mortality. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.10.278DOI Listing
November 2018
8 Reads

Monetary costs and hospital burden associated with the management of invasive fungal infections in Mexico: a multicenter study.

Braz J Infect Dis 2018 Sep - Oct;22(5):360-370. Epub 2018 Nov 2.

Hospital Universitario "Dr. José Eleuterio González" UANL, Servicio de infectología, epidemiología hospitalaria y microbiología, Nuevo León, Mexico.

Background: Invasive fungal infections (IFIs) affect >1.5 million people per year. Nevertheless, IFIs are usually neglected and underdiagnosed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183053
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http://dx.doi.org/10.1016/j.bjid.2018.10.277DOI Listing
January 2019
14 Reads

Antiretroviral therapy immunologic non-response in a Brazilian population: association study using pharmaco- and immunogenetic markers.

Braz J Infect Dis 2018 Sep - Oct;22(5):392-401. Epub 2018 Oct 28.

Universidade Federal de Pernambuco, Departamento de Genética, Recife, PE, Brazil; Uiversità degli studi di Trieste, IRCCS Burlo Garofolo, Trieste, Italy.

Background: Antiretroviral therapy (ART) saved millions from HIV-1 infection and AIDS, but some patients do not experience adequate CD4+ T cells gain despite achieving viral suppression. The genetic component of this condition is not yet completely elucidated.

Objective: To identify predictive genetic markers of immune response to ART. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183046
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http://dx.doi.org/10.1016/j.bjid.2018.09.002DOI Listing
January 2019
6 Reads

The influenza season 2016/17 in Bucharest, Romania - surveillance data and clinical characteristics of patients with influenza-like illness admitted to a tertiary infectious diseases hospital.

Braz J Infect Dis 2018 Sep - Oct;22(5):377-386. Epub 2018 Oct 31.

National Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

Background: Influenza continues to drive seasonal morbidity, particularly in settings with low vaccine coverage.

Objectives: To describe the influenza cases and viral circulation among hospitalized patients.

Methods: A prospective study based on active surveillance of inpatients with influenza-like illness from a tertiary hospital in Bucharest, Romania, in the season 2016/17. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183052
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http://dx.doi.org/10.1016/j.bjid.2018.10.275DOI Listing
January 2019
9 Reads

A 19-year old man with IgA vasculitis after vaccination.

Braz J Infect Dis 2018 Sep - Oct;22(5):442-444. Epub 2018 Oct 30.

UTHealth - McGovern Medical School, Division of Infectious Diseases, Department of Internal Medicine, Houston, United States; UTHealth - McGovern Medical School, Center for Antimicrobial Resistance and Microbial Genomics (CARMiG) and Division of Infectious Diseases, Houston, United States; UTHealth - School of Public Health, Center for Infectious Diseases, Houston, United States; Universidad El Bosque, Centro Internacional de Genómica Microbiana, Unidad de Genética Molecular y Resistencia Antimicrobiana, Bogota, Colombia. Electronic address:

A 19-year-old patient who mistakenly received two doses of influenza vaccine 10 days before presentation, was admitted with malaise, weakness, and a purpuric non-blanching rash most prominent on the ankles followed by abdominal pain and hematochezia 72h later. The diagnosis of influenza vaccine-related Henoch-Schonlein vasculitis was made. This complication, although rare, is the most common vasculitis related to immunization. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183056
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http://dx.doi.org/10.1016/j.bjid.2018.09.004DOI Listing
January 2019
18 Reads

Molecular detection of Mycobacterium leprae by Polymerase Chain Reaction in captive and free-ranging wild animals.

Braz J Infect Dis 2018 Sep - Oct;22(5):445-447. Epub 2018 Oct 30.

Universidade Federal do Mato Grosso, Pós-Graduação em Ciências Veterinárias, Departamento de Veterinária, Mato Grosso, MT, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bjid.2018.09.003DOI Listing
October 2018
1 Read

Is community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) an emerging pathogen among children in Brazil?

Braz J Infect Dis 2018 Sep - Oct;22(5):371-376. Epub 2018 Oct 30.

Universidade de São Paulo, Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, Comissão de Controle de Infecção Hospitalar, Ribeirão Preto, SP, Brazil; Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Medicina Social, Ribeirão Preto, SP, Brazil. Electronic address:

Background: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is spreading worldwide, but little is known about the epidemiology of this pathogen in Brazil.

Objective: To evaluate clinical and microbiological features of children with S. aureus infections admitted to a university hospital. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183052
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http://dx.doi.org/10.1016/j.bjid.2018.10.276DOI Listing
January 2019
12 Reads

Mycobacterium tuberculosis complex bacteremia among HIV and non-HIV patients in a Mexican tertiary care center.

Braz J Infect Dis 2018 Sep - Oct;22(5):387-391. Epub 2018 Oct 30.

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Medicina, Ciudad de México, Mexico. Electronic address:

Objectives: To determine the factors associated with Mycobacterium tuberculosis complex-positive blood culture.

Methods: Case-control study. Sociodemographic, clinical and laboratory data were collected from 2000 to 2015. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183050
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http://dx.doi.org/10.1016/j.bjid.2018.10.274DOI Listing
January 2019
11 Reads

Viral detection profile in children with severe acute respiratory infection.

Braz J Infect Dis 2018 Sep - Oct;22(5):402-411. Epub 2018 Oct 23.

Universidade Federal do Rio de Janeiro (UFRJ), Faculdade de Medicina, Departamento de Pediatria, Rio de Janeiro, RJ, Brazil.

Objectives: The role of viral co-detection in children with severe acute respiratory infection is not clear. We described the viral detection profile and its association with clinical characteristics in children admitted to the Pediatric Intensive Care Unit (PICU) during the 2009 influenza A(H1N1) pandemic.

Method: Longitudinal observational retrospective study, with patients aged 0-18 years, admitted to 11 PICUs in Rio de Janeiro, with suspected H1N1 infection, from June to November, 2009. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183034
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http://dx.doi.org/10.1016/j.bjid.2018.09.001DOI Listing
January 2019
11 Reads

Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro.

Braz J Infect Dis 2018 Sep - Oct;22(5):412-417. Epub 2018 Oct 16.

Universidade Federal do Rio de Janeiro, Instituto de Puericultura e Pediatria Martagão Gesteira, Departmento de Medicina Preventiva, Rio de Janeiro, RJ, Brazil. Electronic address:

Background: Perinatally HIV-infected children are surviving into adulthood, and getting pregnant. There is a scarcity of information on health and pregnancy outcomes in these women.

Aim: To evaluate characteristics related to HIV disease and pregnancy outcomes in perinatally infected women, and to compare these women with a group of youth with behaviorally acquired HIV-infection, at a reference hospital in Rio de Janeiro, Brazil. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183040
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http://dx.doi.org/10.1016/j.bjid.2018.08.005DOI Listing
January 2019
11 Reads

Ventilator-associated pneumonia agents in Brazilian Neonatal Intensive Care Units - a systematic review.

Braz J Infect Dis 2018 Jul - Aug;22(4):338-344. Epub 2018 Jul 5.

Universidade Federal Fluminense, Faculdade de Medicina, Departamento Materno-Infantil, Laboratório de Ensino em Controle e Prevenção de Infecções Relacionadas à Assistência à Saúde, Niterói, Brazil.

Introduction: Ventilator-associated pneumonia (VAP) is one of the most common healthcare-associated infections (HAI) in neonates admitted in neonatal intensive care units (NICUs).

Methods: We did a systematic review using PRISMA methodology to identify the main etiological agents in Brazilian NICUs. Eligible studies published without period restriction were identified in PUBMED, SCIELO, LILACS and DOAJ. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183022
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http://dx.doi.org/10.1016/j.bjid.2018.06.002DOI Listing
October 2018
12 Reads

Multidrug-resistant Acinetobacter baumannii clones persist on hospital inanimate surfaces.

Braz J Infect Dis 2018 Sep - Oct;22(5):438-441. Epub 2018 Sep 25.

Fundação Oswaldo Cruz (FIOCRUZ), Instituto Aggeu Magalhães, Recife, PE, Brazil.

Acinetobacter baumannii is one of the most frequent Gram-negative opportunistic pathogens associated with hospital-acquired infection worldwide. We briefly describe A. baumannii isolates that were recovered from surrounding ICU bed surfaces, exhibiting multidrug resistance phenotype and belonging to some widely spread clonal complexes of clinical A. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183032
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http://dx.doi.org/10.1016/j.bjid.2018.08.004DOI Listing
January 2019
22 Reads

One-step real-time PCR assay for detection and quantification of RNA HCV to monitor patients under treatment in Brazil.

Braz J Infect Dis 2018 Sep - Oct;22(5):418-423. Epub 2018 Sep 20.

Federal University of Rio de Janeiro - UFRJ, Brazil.

The Brazilian Public Health Service provides freely αPEG-IFN to treat patients infected with HCV. The primary goal of HCV therapy is the long-term elimination of HCV from the blood to reduce the risk of HCV associated complications and death. Patient viremia affects the treatment duration and response, thus influencing clinical decisions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183031
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http://dx.doi.org/10.1016/j.bjid.2018.08.003DOI Listing
January 2019
8 Reads

Increasing prevalence and dissemination of invasive nontyphoidal Salmonella serotype Typhimurium with multidrug resistance in hospitalized patients from southern Brazil.

Braz J Infect Dis 2018 Sep - Oct;22(5):424-432. Epub 2018 Sep 18.

Universidade Luterana do Brasil (ULBRA), Programa de Pós-Graduação em Biologia Celular e Molecular Aplicada à Saúde, Canoas, RS, Brazil; Simbios Biotecnologia, Cachoeirinha, RS, Brazil.

Introduction: Nontyphoidal Salmonella serotypes are the main cause of human food-borne infection, including several hospitalization cases in the developing countries.

Aim: To detect the main serotypes and to characterize the antibiotic resistance of human non-enteric and enteric nontyphoidal Salmonella from clinical isolates in Brazil.

Methods: Salmonella serotypes were identified by microbiological and molecular methods. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.08.002DOI Listing
January 2019
2 Reads

Incidence of surgical site infection after craniotomy: comparison between three months and twelve months of epidemiological surveillance.

Braz J Infect Dis 2018 Sep - Oct;22(5):433-437. Epub 2018 Sep 12.

Universidade Federal de São Paulo, Hospital São Paulo, Departamento de Doenças Infecciosas, São Paulo, SP, Brazil; Universidade Federal de São Paulo, Hospital São Paulo, Comitê de Epidemiologia Hospitalar, São Paulo, SP, Brazil.

Objective: To determine the incidence of surgical site infection in patients undergoing craniotomy and to compare 12-month and 3-month post-discharge surveillance periods in terms of their impact on the incidence of surgical site infection in those patients.

Methods: This was a retrospective cohort study involving 173 adult patients submitted to "clean" craniotomy, with or without implants, during the six-month period, at a university hospital in the city of São Paulo, Brazil. All the patients were evaluated in the pre-, trans- and postoperative periods and were followed for 12 months to analyze the development of surgical site infections. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.08.001DOI Listing
January 2019
1 Read

Differences in the replicative capacities of clinical isolates of dengue virus in C6/36 cells and in urban populations of Aedes aegypti from Colombia, South America.

Braz J Infect Dis 2018 Jul - Aug;22(4):257-272. Epub 2018 Aug 28.

Universidad Cooperativa de Colombia, Facultad de Medicina Veterinaria y Zootecnia, Grupo de Investigación en Ciencias Animales-GRICA, Bucaramanga, Colombia. Electronic address:

Dengue, the most prevalent arboviral disease worldwide, is caused by any of the four dengue virus (DENV) serotypes that co-circulate constantly in hyperendemic areas such as Medellin (Colombia), and these serotypes are transmitted by mosquitoes of the genus Aedes. In this study, we evaluated the replicative capacity of strains isolated in Medellin between 2003 and 2007 in C6/36 cells and in colonies of Aedes aegypti collected during 2010-2011 from high or low-incidence areas within the same city. The phylogenetic analysis grouped isolates according to the predominant genotypes found in the Americas, and the in vitro characterization showed differences in the morphological changes induced by the isolates of each of the isolated serotypes compared to the reference serotypes. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.07.010DOI Listing
October 2018
13 Reads

The impact of urinary incontinence on the quality of life and on the sexuality of patients with HAM/TSP.

Braz J Infect Dis 2018 Jul - Aug;22(4):288-293. Epub 2018 Aug 24.

Instituto de Infectologia Emilio Ribas, Coordenação de Neurologia, São Paulo, SP, Brazil.

This study evaluated the impact of urinary incontinence (UI) on sexuality, body image, mood, and quality of life of patients with myyelopathy associated with HTLV-1/tropical spastic paraparesis (HAM/TSP). The sample consisted of 31 HAM/TSP outpatients, of both sexes, followed-up at the Emílio Ribas Infectology Institute. The following instruments were used: sociodemographic questionnaire, Hospital Anxiety and Depression Scale (HAD), Body Image Assessment Scale, Sexual Quotient Female (QS-F) and Male (QS-M) Versions, King's Health Questionnaire (KHQ), and Revised OSAME Motor Disability Score. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.07.003DOI Listing
October 2018
10 Reads

Clostridium difficile contamination in retail meat products in Brazil.

Braz J Infect Dis 2018 Jul - Aug;22(4):345-346. Epub 2018 Aug 23.

Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, RS, Brazil; Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil. Electronic address:

Introduction: Clostridium difficile is an important cause of diarrhoea, particularly in patients receiving antibiotic therapy. Recent studies have shown that a substantial proportion of C. difficile infections are acquired in the community, as a zoonotic disease. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183038
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http://dx.doi.org/10.1016/j.bjid.2018.07.007DOI Listing
October 2018
9 Reads

Inadequate use of antibiotics and increase in neonatal sepsis caused by resistant bacteria related to health care assistance: a systematic review.

Braz J Infect Dis 2018 Jul - Aug;22(4):328-337. Epub 2018 Aug 18.

Universidade Federal de Minas Gerais, Departamento de Pediatria, Belo Horizonte, MG, Brazil.

Background: Technologies and life support management have enhanced the survival of preterm infants. The immune system of newborns is immature, which contributes to the occurrence of healthcare-associated infections. The overlap of several conditions with neonatal sepsis and the difficulty of diagnosis and laboratory confirmation during this period result in a tendency to over-treat neonatal sepsis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183012
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http://dx.doi.org/10.1016/j.bjid.2018.07.009DOI Listing
October 2018
14 Reads

Secular trends of candidemia at a Brazilian tertiary care teaching hospital.

Braz J Infect Dis 2018 Jul - Aug;22(4):273-277. Epub 2018 Aug 16.

Universidade Federal do Rio de Janeiro, Hospital Universitário, Rio de Janeiro, RJ, Brazil. Electronic address:

Background: Candidemia is the most frequent invasive fungal disease in hospitalized patients, and is associated with high mortality rates. The main objective of this study was to evaluate changes in the epidemiology of candidemia at a tertiary care hospital in a 21-year period.

Methods: We evaluated all episodes of candidemia diagnosed between 1996 and 2016 at a University-affiliated tertiary care hospital in Brazil. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.07.008DOI Listing
October 2018
1 Read

Prevalence of hepatitis C among dock workers.

Braz J Infect Dis 2018 Jul - Aug;22(4):355-356. Epub 2018 Aug 16.

Universidade Metropolitana de Santos (UNIMES), Departamento de Infectologia, Mentoria Científica em Infectologia, Santos, SP, Brazil.

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http://dx.doi.org/10.1016/j.bjid.2018.07.006DOI Listing
February 2019
2 Reads

Predominance of Leishmania major and rare occurrence of Leishmania tropica with haplotype variability at the center of Iran.

Braz J Infect Dis 2018 Jul - Aug;22(4):278-287. Epub 2018 Aug 13.

Pasteur Institute of Iran, Parasitology Department, Molecular Systematics Laboratory, Tehran, Iran. Electronic address:

Background: Leishmania major is a causative agent of zoonotic cutaneous leishmaniasis in the center of Iran, Abarkouh district. Molecular characterization and precise incrimination of Leishmania species was carried out to perform controlling measurements and to design treatment programs for zoonotic cutaneous leishmaniasis.

Methods: All smears isolated from ulcers of suspected patients were examined under a light microscope and graded for amastigotes frequency. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.07.005DOI Listing
October 2018
5 Reads
1.100 Impact Factor

Central venous catheter-related infections caused by Corynebacterium amycolatum and other multiresistant non-diphtherial corynebacteria in paediatric oncology patients.

Braz J Infect Dis 2018 Jul - Aug;22(4):347-351. Epub 2018 Aug 11.

Universidade Estadual do Rio de Janeiro (UERJ), Faculdade de Ciências Médicas, Laboratório de Difteria e Corynebacteria de Relevância Clínica, Rio de Janeiro, RJ, Brazil; Ministério da Saúde, Fundação Nacional de Saúde, Centro de Referência e Pesquisa em Difteria, Brasília, DF, Brazil.

Bloodstream and venous catheter-related corynebacterial infections in paediatric patients with haematological cancer were investigated from January 2003 to December 2014 at the Brazilian National Cancer Institute in Rio de Janeiro, Brazil. We observed that during cancer treatment, invasive corynebacterial infections occurred independent of certain factors, such as age and gender, underlying diseases and neutropenia. These infections were ssscaused by Corynebacterium amycolatum and other non-diphtherial corynebacteria. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.07.004DOI Listing
October 2018
4 Reads

Bloodstream infection by mcr-1-harboring Escherichia coli in a cancer patient in southern Brazil.

Braz J Infect Dis 2018 Jul - Aug;22(4):356-357. Epub 2018 Aug 7.

Universidade Federal de Santa Maria, Departamento de Análises Clínicas e Toxicológicas, Laboratório de Bacteriologia, Santa Maria, RS, Brazil; Universidade Federal de Santa Maria, Programa de Pós-Graduação em Ciências Farmacêuticas, Santa Maria, RS, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bjid.2018.07.001DOI Listing
February 2019
1 Read

HBV epidemiology and genetic diversity in an area of high prevalence of hepatitis B in southern Brazil.

Braz J Infect Dis 2018 Jul - Aug;22(4):294-304. Epub 2018 Aug 6.

Universidade Luterana do Brasil (ULBRA), Programa de Pós-Graduação em Biologia Celular e Molecular Aplicada à Saúde, Canoas, RS, Brazil.

Background: Hepatitis B virus (HBV) infection is a major public health problem in Brazil. HBV endemicity is usually moderate to low according to geographic regions, and high prevalence of this virus has been reported in people of some specific Brazilian counties, including those with a strong influence of Italian colonization in southern Brazil. Analysis of HBV diversity and identification of the main risk factors to HBV infection are necessary to understand hepatitis B epidemiology in these high prevalence regions in southern Brazil. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.06.006DOI Listing
October 2018
18 Reads
1.100 Impact Factor

Predictors of mortality in multidrug-resistant tuberculosis patients from Brazilian reference centers, 2005 to 2012.

Braz J Infect Dis 2018 Jul - Aug;22(4):305-310. Epub 2018 Aug 6.

UNITAID, Vernier, Switzerland.

Objectives: To determine the main predictors of death in multidrug-resistant (MDRTB) patients from Brazil.

Design: Retrospective cohort study, a survival analysis of patients treated between 2005 and 2012.

Results: Of 3802 individuals included in study, 64. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.07.002DOI Listing
October 2018
1 Read

Helicobacter pylori eradication: influence of interleukin-1beta -31 C/T polymorphism.

Braz J Infect Dis 2018 Jul - Aug;22(4):311-316. Epub 2018 Jul 24.

Universidade Luterana do Brasil, Laboratório de Genética Molecular Humana, Canoas, RS, Brazil. Electronic address:

Aim: To analyze the influence of the -31 C/T polymorphism of the interleukin-1β gene on Helicobacter pylori eradication therapy success in patients with functional dyspepsia.

Methods: Functional dyspepsia was diagnosed according to the Rome III criteria. All patients underwent upper gastrointestinal endoscopy, and gastric biopsies were obtained at screening and 12 months after randomization (last follow-up visit). Read More

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http://dx.doi.org/10.1016/j.bjid.2018.06.005DOI Listing
October 2018
3 Reads

Effectiveness of chronic hepatitis C treatment with direct-acting antivirals in the Public Health System in Brazil.

Braz J Infect Dis 2018 Jul - Aug;22(4):317-322. Epub 2018 Jul 21.

Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil.

Introduction: Chronic hepatitis C virus infection is one of the major causes of cirrhosis, hepatocellular carcinoma and liver transplantation. Treatment using direct-acting antivirals has revolutionized the treatment of hepatitis C virus, increasing long-term prognosis after cure. The goal of the present study was to evaluate the effectiveness of direct-acting antivirals in a Public Health System in southern Brazil. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.06.004DOI Listing
October 2018
8 Reads

Microbiology and clinical characteristics of viridans group streptococci in patients with cancer.

Braz J Infect Dis 2018 Jul - Aug;22(4):323-327. Epub 2018 Jul 17.

Instituto Nacional de Cancerología, Departamento de Enfermedades Infecciosas, Ciudade de México, Mexico. Electronic address:

This study assessed the microbiology, clinical syndromes, and outcomes of oncologic patients with viridans group streptococci isolated from blood cultures between January 1st, 2013 and December 31st, 2016 in a referral hospital in Mexico using the Bruker MALDI Biotyper. Antimicrobial sensitivity was determined using BD Phoenix 100 according to CLSI M100 standards. Clinical information was obtained from medical records and descriptive analysis was performed. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.06.003DOI Listing
October 2018
3 Reads

Schistosomal liver fibrosis and hepatocellular carcinoma - case series of patients submitted to liver transplantation.

Braz J Infect Dis 2018 Jul - Aug;22(4):352-354. Epub 2018 Jul 12.

Universidade de Pernambuco, Hospital Universitário Oswaldo Cruz, Unidade de Transplante de Fígado, Recife, PE, Brazil.

Schistosomiasis affects approximately 207 million people in 76 countries. The association between hepatocellular carcinoma and Schistosoma mansoni infection has been investigated. Studies using animal models suggest that the parasite may accelerate the oncogenic process when combined with other factors, such as hepatitis C virus infection or exposure to a carcinogen. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.06.001DOI Listing
October 2018
5 Reads

Drug repositioning, a new alternative in infectious diseases.

Braz J Infect Dis 2018 May - Jun;22(3):252-256. Epub 2018 Jun 28.

Universidade Federal de Santa Maria, Programa de Pós-graduacão em Ciências Farmacêuticas, Santa Maria,RS, Brazil; UniversidadeSanta Maria, Departamento de Análises Clínicas e Toxicológicas, Santa Maria, RS, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bjid.2018.05.007DOI Listing
October 2018
2 Reads

Tailoring antimicrobials in febrile neutropenia: using faster diagnostic and communication tools to improve treatment in the era of extensively resistant pathogens.

Braz J Infect Dis 2018 May - Jun;22(3):239-242. Epub 2018 Jun 28.

Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM), Disciplina de Infectologia, São Paulo, SP, Brazil.

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http://dx.doi.org/10.1016/j.bjid.2018.05.009DOI Listing
October 2018
4 Reads

Immediate start of antiretroviral, why not?

Braz J Infect Dis 2018 May - Jun;22(3):250-251. Epub 2018 Jun 22.

Instituto Adolfo Lutz, Centro de Virologia, NDSS, São Paulo, SP, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bjid.2018.05.006DOI Listing
October 2018
3 Reads

An exuberant form of disseminated histoplasmosis.

Braz J Infect Dis 2018 May - Jun;22(3):243-244. Epub 2018 Jun 22.

Dermatologia da Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.

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http://dx.doi.org/10.1016/j.bjid.2018.05.008DOI Listing
October 2018
4 Reads

Low variation in initial CD4 cell count in a HIV referral center, in Salvador, Brazil, from 2002 to 2015.

Braz J Infect Dis 2018 May - Jun;22(3):245-247. Epub 2018 Jun 6.

Universidade Federal da Bahia, Faculdade de Medicina, Complexo Hospitalar Professor Edgard Santos, LAPI - Laboratório de Pesquisa em Infectologia, Salvador, BA, Brazil. Electronic address:

Early initiation of antiretroviral therapy increases the likelihood of effective immune restoration, quality of life, and greater life expectancy for HIV-infected individuals. We evaluated the evolution of mean CD4+ cells count at diagnosis of HIV/AIDS in Salvador, Brazil from 2002 to 2015. We identified HIV/AIDS patients older than 18 years with diagnosis of HIV infection from 2002 to 2015, who had their first laboratory evaluation at Complexo Hospitalar Prof. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.05.005DOI Listing
July 2018
5 Reads

Re-emergence of human T-lymphotropic viruses in West Africa.

Braz J Infect Dis 2018 May - Jun;22(3):224-234. Epub 2018 Jun 5.

Ahmadu Bello University, Faculty of Life Sciences, Department of Microbiology, Zaria, Nigeria.

Human T-lymphotropic viruses (HTLV) are Deltaretroviruses that infect millions of individuals worldwide via the same transmission routes as HIV. With the aim of exposing the possible re-emergence of HTLV in West Africa since discovery, a systematic review was carried out, focusing on the distribution of the virus types and significance of frequent indeterminate reports, while highlighting the need for mandatory routine blood screening. Capturing relevant data from discovery till date, sources searched were Google Scholar, CrossRef, NCBI (PubMed), MEDLINE, Research Gate, Mendeley, abstracts of Conferences and Proceedings, organization websites and reference lists of selected papers. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183015
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http://dx.doi.org/10.1016/j.bjid.2018.05.003DOI Listing
July 2018
5 Reads

Impact of A/H1N1 influenza in children at a Brazilian University Hospital.

Braz J Infect Dis 2018 May - Jun;22(3):219-223. Epub 2018 Jun 5.

Hospital de Clínicas de Porto Alegre (HCPA), Residência em Pediatria, Porto Alegre, RS, Brazil.

Background: A/H1N1 influenza is a viral disease that affects a significant part of the population mainly in winter, leading to increased number of medical consultations, hospitalizations and consequently care spending in emergency.

Methods: This is a case-series retrospective study, involving patients admitted to a tertiary hospital in southern Brazil in 2016 with a clinical diagnosis of acute respiratory infection of the influenza type and laboratory confirmation of influenza A/H1N1.

Results: 64 patients were included, mostly male, median age of 48. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.05.004DOI Listing
July 2018
3 Reads

Trypanosoma cruzi: analysis of two different strains after piplartine treatment.

Braz J Infect Dis 2018 May - Jun;22(3):208-218. Epub 2018 Jun 5.

Universidade Estadual Paulista - UNESP, Faculdade de Ciências Farmacêuticas, Araraquara, SP, Brazil. Electronic address:

The hemoflagellate protozoan, Trypanosoma cruzi, mainly transmitted by triatomine insects through blood transfusion or from mother-to-child, causes Chagas' disease. This is a serious parasitic disease that occurs in Latin America, with considerable social and economic impact. Nifurtimox and benznidazole, drugs indicated for treating infected persons, are effective in the acute phase, but poorly effective during the chronic phase. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.02.009DOI Listing
July 2018
7 Reads