47,877 results match your criteria Brazilian Journal Of Botany[Journal]


One year cross-sectional study in adult and neonatal intensive care units reveals the bacterial and antimicrobial resistance genes profiles in patients and hospital surfaces.

PLoS One 2020 3;15(6):e0234127. Epub 2020 Jun 3.

BiomeHub, Florianopolis, Brazil.

Several studies have shown the ubiquitous presence of bacteria in hospital surfaces, staff, and patients. Frequently, these bacteria are related to HAI (healthcare-associated infections) and carry antimicrobial resistance (AMR). These HAI-related bacteria contribute to a major public health issue by increasing patient morbidity and mortality during or after hospital stay. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234127PLOS

Uncovering episodic influence of oceans on extreme drought events in Northeast Brazil by ordinal partition network approaches.

Chaos 2020 May;30(5):053104

CEMADEN, Brazilian National Center for Monitoring and Early Warning of Natural Disasters, São José dos Campos 12245-320, São Paulo, Brazil.

Since 2012, the semiarid region of Northeast Brazil (NEB) has been experiencing a continuous dry condition imposing significant social impacts and economic losses. Characterizing the recent extreme drought events and uncovering the influence from the surrounding oceans remain to be big challenges. The physical mechanisms of extreme drought events in the NEB are due to varying interacting time scales from the surrounding tropical oceans (Pacific and Atlantic). Read More

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http://dx.doi.org/10.1063/5.0004348DOI Listing

The different tests for the diagnosis of COVID-19 - A review in Brazil so far.

JBRA Assist Reprod 2020 Jun 3. Epub 2020 Jun 3.

Igenomix, São Paulo - SP.

SARS-CoV-2 is a novel virus from the coronavirus family that emerged in the end of December 2019 in Wuhan, China. The virus is now widespread and causing the current pandemic of COVID-19, a highly pathogenic viral pneumonia, commonly presented with fever and cough, which frequently lead to lower respiratory tract disease with poor clinical outcomes associated with older age and underlying health conditions. Supportive care for patients is typically the standard protocol because no specific effective antiviral therapies have been identified so far. Read More

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http://dx.doi.org/10.5935/1518-0557.20200046DOI Listing

Mapping carbon and nitrogen isotopic composition of fingernails to demonstrate a rural-urban nutrition transition in the Center-West, Northeast, and Amazon regions of Brazil.

Am J Phys Anthropol 2020 Jun 3. Epub 2020 Jun 3.

Laboratório de Ecologia Isotópica, CENA, Universidade de São Paulo, Piracicaba, Brazil.

Objective: The main objective of this study is to investigate diet patterns among rural and urban populations of the Center-West, Northeast, and Amazon regions of Brazil through the carbon and nitrogen isotopic composition of fingernails, recognizing that the extent of market integration is a key driver of food consumption.

Materials And Methods: In the Center-West, Northeast, and Amazon regions of Brazil, fingernails were sampled in clusters encompassing a major city, town, and rural village. A total of 2,133 fingernails were analyzed. Read More

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http://dx.doi.org/10.1002/ajpa.24078DOI Listing

Percutaneous Transseptal Bioprosthetic Implantation in Failed Prosthetic Surgical Mitral Valve - Brazilian Multicenter Experience.

Arq Bras Cardiol 2020 May 29. Epub 2020 May 29.

Hospital de Força Aérea do Galeão, Rio de Janeiro, RJ, Brasil.

Background Percutaneous intervention in patients with bioprosthetic mitral valve dysfunction is an alternative to conventional surgical treatment. Objectives To report the first Brazilian experience with transseptal transcatheter bioprosthetic mitral valve-in-valve implantation (transseptal-TMVIV). Methods Patients with surgical bioprosthetic dysfunction submitted to transseptal-TMVIV in 12 Brazilian hospitals were included. Read More

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http://dx.doi.org/10.36660/abc.20190252DOI Listing

Effects of dry and traditional bed bathing on respiratory parameters: a randomized pilot study.

Rev Lat Am Enfermagem 2020 1;28:e3264. Epub 2020 Jun 1.

Escola de Enfermagem, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.

Objective: to compare the time for performance of dry and traditional bed bathing and its effects on transcutaneous arterial oxygen saturation and respiratory rates in critical adult patients.

Method: pilot study of a randomized, open, crossover clinical trial, performed with 15 adult critically ill patients. Each patient received a dry and a traditional bed bath. Read More

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http://dx.doi.org/10.1590/1518-8345.3668.3264DOI Listing

Nurse Navigator: development of a program for Brazil.

Rev Lat Am Enfermagem 2020 1;28:e3275. Epub 2020 Jun 1.

Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil.

Objective: to develop a Navigation Program for cancer patients, based on the model proposed by The GW Cancer Institute at George Washington University, adapted to the reality of a Brazilian High Complexity Center in Oncology.

Method: a convergent care research applied in the development of a patient navigation care process, based on the model proposed by George Washington University, adapted for a High Complexity Center in Oncology in Brazil. Phases of the Convergent Assistance Research: conception, instrumentation, scrutiny, analysis and interpretation. Read More

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http://dx.doi.org/10.1590/1518-8345.3258.3275DOI Listing

Neighborhood environmental factors associated with leisure walking in adolescents.

Rev Saude Publica 2020 1;54:61. Epub 2020 Jun 1.

Programa de Pós-Graduação em Ciências do Movimento Humano, Escola de Educação Física, Fisioterapia e Dança, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.

OBJECTIVE To verify the associations of leisure walking with perceived and objective measures of neighborhood environmental factors stratified by gender and socioeconomic status (SES) in Brazilian adolescents. METHODS Cross-sectional study with a random sample of 1,130 high school students (47.3% girls; aged 14 to 20 years old) from Porto Alegre, Brazil. Read More

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http://dx.doi.org/10.11606/s1518-8787.2020054002222DOI Listing

Food advertisements on television and eating habits in adolescents: a school-based study.

Rev Saude Publica 2020 1;54:55. Epub 2020 Jun 1.

Departamento de Educação Física, Faculdade de Ciências e Tecnologia, Universidade Estadual Paulista, Presidente Prudente, SP, Brasil.

OBJECTIVE To analyze the association of television food advertisements with eating habits in Brazilian adolescents. METHODS The sample was composed of 1,011 adolescents, aged from 10-17 years. The influence of television food advertisements on eating habits, as well as food consumption and socioeconomic variables were assessed through questionnaires. Read More

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http://dx.doi.org/10.11606/s1518-8787.2020054001558DOI Listing

Brazilian cohorts with potential for life-course studies: a scoping review.

Rev Saude Publica 2020 20;54:48. Epub 2020 May 20.

Departamento de Medicina Preventiva, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.

OBJECTIVE To identify the Brazilian cohorts that started either in the prenatal period or at birth, to describe their characteristics and the explored variables, and to map the cohorts with potential for studies on early determinants on health and the risk of falling ill on later stages of the life cycle. METHODS A scoping review was carried out. The articles were searched in the electronic databases PubMed and Virtual Health Library (VHL). Read More

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http://dx.doi.org/10.11606/s1518-8787.2020054001825DOI Listing

International Classification of Functioning in professional rehabilitation: instruments for assessing work disability.

Rev Saude Publica 2020 20;54:45. Epub 2020 May 20.

Programa de Epidemiologia Clínica, Instituto Nacional de Câncer, Rio de Janeiro, RJ, Brasil.

OBJECTIVE To review the main instruments of functional assessment and health status cited in the literature to evaluate Brazilian workers and verify the compatibility of their items with the core set for professional rehabilitation. METHODS A review of the literature was conducted in the main databases in search of articles that used assessment instruments in populations of workers between 2007 and 2017. Subsequently, the contents of the identified instruments were retrieved, and two evaluators analyzed their items to verify the compatibility with the categories of the core set of the International Classification of Functioning for professional rehabilitation. Read More

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http://dx.doi.org/10.11606/s1518-8787.2020054001463DOI Listing

Chronic low back pain and physical activity among patients within the Brazilian National Health System: a cross-sectional study.

Sao Paulo Med J 2020 Mar 1;138(2):106-111. Epub 2020 Jun 1.

Department of Physical Education and Postgraduate Physiotherapy Program, Faculdade de Ciências e Tecnologia, Universidade Estadual Paulista, Presidente Prudente, SP, Brazil.

Background: This study was based on filling a gap in our knowledge regarding the issue of what the protective effect of physical exercise on patients within the Brazilian National Health System could be, in relation to low back pain.

Objectives: To determine the prevalence of chronic low back pain (CLBP) and to analyze the protective effect of physical exercise among patients over 50 years old attended at primary healthcare units (PHUs).

Design And Setting: Analytical cross-sectional study at Universidade Estadual Paulista (UNESP) that was conducted in two PHUs (Parque Cedral and Vila Real), located in different regions of the city of Presidente Prudente, Brazil. Read More

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http://dx.doi.org/10.1590/1516-3180.2019.0312.r1.19112019DOI Listing

Influence of air pollutants on pneumonia hospitalizations among children in a town in the Brazilian Legal Amazon region: a time series study.

Sao Paulo Med J 2020 Mar 1;138(2):126-132. Epub 2020 Jun 1.

Postgraduate Program on Environment and Health, Universidade de Cuiabá, Cuiabá, MT, Brazil.

Background: Exposure to particulate material produced as a result of increased agricultural activity may increase the number of pneumonia hospitalizations among children. We hope to contribute to the knowledge base through highlighting the environmental mechanisms involved in this outcome and optimizing pollutant control policies.

Objectives: To investigate the association between pneumonia hospitalizations among children and presence of environmental pollutants in a town in the Brazilian Legal Amazon region. Read More

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http://dx.doi.org/10.1590/1516-3180.2019.0456.r1.09122019DOI Listing

Validity Evidence of the Brazilian Version of the Florida Shock Anxiety Scale for Patients with Implantable Cardioverter Defibrillators.

Arq Bras Cardiol 2020 Jun;114(5):764-772

East Carolina University - Department of Psychology and Cardiovascular Sciences Greenville, North Carolina - USA.

Background: In spite of proven effectiveness of implantable cardioverter defibrillators (ICDs), shock therapy delivered by the device may result in increased levels of anxiety and depression, leading to deleterious effects on quality of life.

Objective: To carry out the translation, cross-cultural adaptation and validation of the Florida Shock Anxiety Scale (FSAS) scale into Brazilian Portuguese.

Methods: In this psychometric study, construct validity was performed by exploratory (EFA) and confirmatory (CFA) factor analyses, and by item response theory (IRT). Read More

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http://dx.doi.org/10.36660/abc.20190255DOI Listing

Community ecology of the metazoan parasites of the Atlantic thread herring, Opisthonema oglinum (Lesueur, 1818) (Actinopterygii: Clupeidae) from the Sepetiba Bay, Rio de Janeiro, Brazil.

Authors:
L Chaves F Paschoal

Braz J Biol 2020 May 29. Epub 2020 May 29.

Laboratório de Parasitologia Animal, Centro de Pesquisas em Biologia, Universidade Castelo Branco, Rio de Janeiro, RJ, Brasil.

This study aimed to evaluate the parasitic fauna of Opisthonema oglinum (Lesueur, 1818) from Southeastern Brazil. Between September 2017 and March 2018, a total of 100 specimens of O. oglinum from the Sepetiba Bay, Rio de Janeiro, Brazil (22°54'S, 43°34'W) were examined. Read More

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http://dx.doi.org/10.1590/1519-6984.229814DOI Listing

Prevalence of autosomal dominant polycystic kidney disease in Persian and Persian-related cats in Brazil.

Braz J Biol 2020 May 29. Epub 2020 May 29.

Departamento de Patologia, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, SP, Brasil.

Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic disease in cats. However, scarce data on its prevalence are available in Brazil. Persian cats and Persian-related breeds were assessed by molecular genotyping for a C to A transversion in exon 29 of PKD1 gene to determine ADPKD prevalence in a Brazilian population. Read More

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http://dx.doi.org/10.1590/1519-6984.227131DOI Listing

Trend of social iniquities in reports of sexual violence in Brazil between 2010 and 2014.

Rev Bras Epidemiol 2020 1;23:e200038. Epub 2020 Jun 1.

Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil.

Introduction: Sexual violence has emerged in the health field with changes in the epidemiological profiles of populations.

Methodology: An ecological study with 5,565 Brazilian municipalities between 2010 and 2014. A descriptive analysis of the variables (Population rate of sexual violence reporting, household income per capita and HDI) and their stratification by quintile was performed. Read More

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http://dx.doi.org/10.1590/1980-549720200038DOI Listing

Metabolic syndrome: physical inactivity and socioeconomic inequalities among non-institutionalized Brazilian elderly.

Rev Bras Epidemiol 2020 1;23:e200046. Epub 2020 Jun 1.

Instituto de Pesquisa René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.

Objective: Evaluate the association between Metabolic Syndrome (MetS), physical activity and socioeconomic conditions among non-institutionalized elderly individuals.

Methodology: Cross-sectional study with, elderly individuals (≥ 60) living in the city of São Paulo. MetS was evaluated by means of the National Cholesterol Education Program criteria, the Adult Treatment Panel III. Read More

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http://dx.doi.org/10.1590/1980-549720200046DOI Listing

Weight gain and changes in nutritional status of Brazilian adults after 20 years of age: a time-trend analysis (2006-2012).

Rev Bras Epidemiol 2020 1;23:e200045. Epub 2020 Jun 1.

Faculdade de Nutrição, Universidade Federal de Alagoas, Maceió, AL, Brazil.

Objective: To analyze weight gain (WG) and change in nutritional status (NS) after the age of 20 years in the Brazilian adult population between 2006 and 2012.

Methods: Time series using seven surveys from the Surveillance of Risk and Protective Factors for Chronic Diseases by Telephone Survey (VIGITEL). The analyses were stratified by region, age, sex and education, considering the sampling weights and complex design. Read More

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http://dx.doi.org/10.1590/1980-549720200045DOI Listing

Exposure to Community and Family violence and self-rated health in the Brazilian population.

Rev Bras Epidemiol 2020 1;23:e200039. Epub 2020 Jun 1.

Departamento de Medicina Preventiva, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.

Introduction: The isolated negative impacts of community violence and family violence on individuals' self-rated health (SRH) are known, but there is little evidence on the combined effect of these two types of interpersonal violence.

Objective: To analyze the association between exposure to community violence/by strangers and family violence/by acquaintances and negative SRH, distinguishing the type of violence suffered and also considering its cumulative exposure.

Methods: Epidemiological cross-sectional study developed with data from the National Health Survey (PNS) 2013. Read More

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http://dx.doi.org/10.1590/1980-549720200039DOI Listing

Care-seeking as a proxy indicator of the mental health of elderly Brazilians.

Braz J Psychiatry 2020 Jun 1. Epub 2020 Jun 1.

Centro de Integração de Dados e Conhecimentos para Saúde (CIDACS), Salvador, BA, Brazil.

Objective: To assess a large set of metadata made public by the Brazilian Ministry of Health on older subjects who visited outpatient mental health services in Brazil from 2008 to 2012.

Methods: We extracted data from the Brazilian Unified Health System Information Technology Department (Departamento de Informática do Sistema Único de Saúde, DATASUS), then calculated rates of visits per population in each of the five regions of Brazil, using census data for each year. Finally, logistic regressions were performed with depressive disorders or dementias as dependent variables, controlled by age and year of visit, stratified by region. Read More

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http://dx.doi.org/10.1590/1516-4446-2019-0721DOI Listing

Mild and moderate cognitive impairment and mortality among Brazilian older adults in long-term follow-up: The Bambui Health Aging Study.

Braz J Psychiatry 2020 Jun 1. Epub 2020 Jun 1.

Núcleo de Estudos em Saúde Pública e Envelhecimento, Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.

Objective: To compare mortality in older adults with and without mild or moderate cognitive impairment over 15 years of follow-up in a middle-income country, where little information on this subject is available.

Methods: A total of 1,281 community-dwelling older adults were followed-up for a median of 13.3 years. Read More

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http://dx.doi.org/10.1590/1516-4446-2019-0654DOI Listing

The trauma and acute care surgeon in the COVID-19 pandemic era.

Rev Col Bras Cir 2020 29;47:e20202576. Epub 2020 May 29.

Grupo Surgical, Campinas, SP, Brasil.

The World Health Organization recognized in March 2020 the existence of a pandemic for the new coronavirus that appeared in China, in late 2019, and whose disease was named COVID-19. In this context, the SBAIT (Brazilian Society of Integrated Care for Traumatized Patients) conducted a survey with 219 trauma and emergency surgeons regarding the availability of personal protective equipment (PPE) and the role of the surgeon in this pandemic by means of an electronic survey. It was observed that surgeons have been acting under inadequate conditions, with a lack of basic supplies as well as more specific equipment such as N95 masks and facial shields for the care of potential victims who may be contaminated. Read More

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http://dx.doi.org/10.1590/0100-6991e-20202576DOI Listing

Short Editorial: Ser49Gly Beta1-adrenergic Receptor Genetic Polymorphism as a Death Predictor in Brazilian Patients with Heart Failure.

Arq Bras Cardiol 2020 Apr 29;114(4):625-626. Epub 2020 May 29.

Departamento de Cardiopneumologia, FMUSP, São Paulo, SP, Brasil.

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http://dx.doi.org/10.36660/abc.20200183DOI Listing

Ser49Gly Beta1-Adrenergic Receptor Genetic Polymorphism as a Death Predictor in Brazilian Patients with Heart Failure.

Arq Bras Cardiol 2020 Apr 29;114(4):616-624. Epub 2020 May 29.

Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.

Background The role of Ser49Gly beta1-adrenergic receptor genetic polymorphism (ADBR1-GP-Ser49Gly) as a predictor of death in heart failure (HF) is not established for the Brazilian population. Objectives To evaluate the association between ADBR1-GP-Ser49Gly and clinical outcomes in individuals with HF with reduced ejection fraction. Methods Secondary analysis of medical records of 178 patients and genotypes of GPRβ1-Ser49Gly variants, classified as Ser-Ser, Ser-Gly and Gly-Gly. Read More

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http://dx.doi.org/10.36660/abc.20190187DOI Listing

Content Translation And Validation Of The Pediatric PIV Infiltration Scale Into Brazilian Portuguese.

Rev Bras Enferm 2020 1;73(4):e20190300. Epub 2020 Jun 1.

Universidade Federal do Ceará, Fortaleza, Ceará, Brasil.

Objectives: to translate, adapt and validate the PIV Infiltration Scale content into Brazilian Portuguese.

Methods: a methodological study. Initial translation was performed by two bilingual translators, translation synthesis; backtranslation to the original language; elaboration of the translated version and adapted by expert consensus; content validation and pretest. Read More

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http://dx.doi.org/10.1590/0034-7167-2019-0300DOI Listing

Structure and spatial distribution of the rotifer assemblages along a tropical reservoir.

Braz J Biol 2020 May 20. Epub 2020 May 20.

Centro de Ciências Agrárias, Ambientais e Biológicas, Universidade Federal do Recôncavo da Bahia, Cruz das Almas, BA, Brasil.

The construction of reservoirs is a common practice in the world. These systems modify the hydric landscape and alter the flow of rivers, becoming lotic environments in lentic. Here we investigated the structure and spatial distribution of rotifers along a tropical reservoir. Read More

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http://dx.doi.org/10.1590/1519-6984.226446DOI Listing

Diet of a bromeligenous species of treefrog in the Brazilian semiarid.

Braz J Biol 2020 May 20. Epub 2020 May 20.

Departamento de Ciências Biológicas, Universidade Estadual do Sudoeste da Bahia, Jequié, BA, Brasil.

Phyllodytes tuberculosus is a bromeligenous anuran species whose geographic distribution is restricted to areas of the Caatinga and to transition zones between Caatinga and Atlantic Forest in the central-south of the state of Bahia. Its existence in close relationship with bromeliads and its occurrence in dry and highly seasonal environments drove us to the supposition that species is opportunistic/generalist regard to diet. We collected the items present in the stomach of 43 P. Read More

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http://dx.doi.org/10.1590/1519-6984.229742DOI Listing

Binge drinking and overweight in brazilian adults - CUME Project.

Rev Bras Enferm 2020 1;73 Suppl 1:e20190316. Epub 2020 Jun 1.

Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Objective: To verify the association between heavy episodic alcohol consumption [binge drinking (BD)] and overweight in 2,909 adults from the Cohort of Universities of Minas Gerais (CUME Project) baseline, Brazil.

Method: Cross-sectional study in which sociodemographic, anthropometric (BMI ≥ 25 kg/m2 = overweight) and dietary intake data were collected. This study evaluated the occurrence and monthly frequency of BD (≥ 4 drinks at one time for women; ≥ 5 drinks at one time for men, in the last 30 days). Read More

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http://dx.doi.org/10.1590/0034-7167-2019-0316DOI Listing

An intervention for the implementation of clinical monitoring in specialized care services to people living with HIV/AIDS.

Cad Saude Publica 2020 1;36(5):e00136219. Epub 2020 Jun 1.

Centro de Referência e Treinamento DST/AIDS-SP-Coordenação do Programa Estadual de IST/AIDS, São Paulo, Brasil.

The clinical monitoring of people living with HIV/AIDS (PLWHA) contributes to identifying and managing cases of individuals who have not begun treatment (gap), those experiencing treatment failure or who have abandoned treatment. This article sought to present and discuss the development of a methodology to implement the clinical monitoring of PLWHA in the services of the Brazilian Unified National Health System (SUS). The methodology used since 2014 by the CRT-STI/AIDS-Coordination of the STI/AIDS Program, São Paulo State, Brazil, was re-structured in three meetings between June and August 2018. Read More

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http://dx.doi.org/10.1590/0102-311x00136219DOI Listing

[Markers of inequality in self-rated health in Brazilian adults according to sex].

Cad Saude Publica 2020 1;36(5):e00230318. Epub 2020 Jun 1.

Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil.

The aim of this study was to analyze self-rated health in Brazil's adult population according to markers of health inequality (color or race, region of residence, schooling, per capita household income, and social class), stratified by sex. We studied 59,758 individuals 18 years or older who participated in the 2013 National Health Survey, a population-based household survey. Data collection used face-to-face interviews and key physical measurements. Read More

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http://dx.doi.org/10.1590/0102-311x00230318DOI Listing

Challenges and opportunities for telehealth during the COVID-19 pandemic: ideas on spaces and initiatives in the Brazilian context.

Cad Saude Publica 2020 1;36(5):e00088920. Epub 2020 Jun 1.

Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.

COVID-19 has created enormous challenges for health systems worldwide, with the rapidly growing number of deaths and critical patients with pneumonia requiring ventilatory support. Alternative methods to control the spread of the disease such as social isolation, extreme quarantine measures, and contact tracing have been used around the world. However, these measures may not be totally effective to fight COVID-19, in step with the necessary national preparations to meet the new patient care demands. Read More

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http://dx.doi.org/10.1590/0102-311x00088920DOI Listing

[Implementation of the More Doctors Program in Espírito Santo State, Brazil: logic model and proposed indicators].

Cad Saude Publica 2020 1;36(5):e00043219. Epub 2020 Jun 1.

University of Massachusetts Boston, Boston, USA.

The study aimed to assess the implementation of the More Doctors Program (PMM in Portuguese) based on a case study of the Espírito Santo State, Brazil. The first stage involved analyzing the documents that launched the PMM, allowing the creation of a logic model. In the second stage, data on the PMM in Espírito Santo State were analyzed (2013-2016) based on population brackets, creating indicators for the proportion of physicians before and after the Program with the following parameters: unacceptable (0 to 0. Read More

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http://dx.doi.org/10.1590/0102-311x00043219DOI Listing

Distinct models to assess the cost-effectiveness of EGFR-tyrosine kinase inhibitors for the treatment of metastatic non-small cell lung cancer in the context of the Brazilian Unified Health Care System.

J Bras Pneumol 2020 1;46(4):e20180255. Epub 2020 Jun 1.

Centro de Estudos e Pesquisa de Hematologia e Oncologia, Faculdade de Medicina do ABC, Santo André, SP, Brazil.

Objective: Lung cancer is an important health problem due to its high incidence and mortality. The treatment of metastatic disease improved after the molecular pathways of cancer came to be known. However, targeted therapy is unavailable to many patients treated within the Brazilian Sistema Único de Saúde (SUS, Unified Health Care System). Read More

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http://dx.doi.org/10.36416/1806-3756/e20180255DOI Listing

Progression of confirmed COVID-19 cases after the implementation of control measures.

Rev Bras Ter Intensiva 2020 May 22. Epub 2020 May 22.

Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brasil.

Objective: To analyse the measures adopted by countries that have shown control over the transmission of coronavirus disease 2019 (COVID-19) and how each curve of accumulated cases behaved after the implementation of those measures.

Methods: The methodology adopted for this study comprises three phases: systemizing control measures adopted by different countries, identifying structural breaks in the growth of the number of cases for those countries, and analyzing Brazilian data in particular.

Results: We noted that China (excluding Hubei Province), Hubei Province, and South Korea have been effective in their deceleration of the growth rates of COVID-19 cases. Read More

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http://dx.doi.org/10.5935/0103-507x.20200028DOI Listing

Brazilian red propolis extract enhances expression of antioxidant enzyme genes and .

Biosci Biotechnol Biochem 2020 Jun 3:1-11. Epub 2020 Jun 3.

Nagaragawa Research Center, API Co., Ltd , Gifu, Japan.

Brazilian red propolis reportedly has reactive oxygen species (ROS) scavenging effects , but the cellular mechanisms remain unclear. In the present study, the effects of an ethanol extract of Brazilian red propolis (EERP) on the Nrf2-ARE intracellular antioxidant pathway were examined and . EERP and its constituents transactivated the reporter gene through the ARE sequence and enhanced the expression of Nrf2-regulated genes in HEK293 cells. Read More

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http://dx.doi.org/10.1080/09168451.2020.1773756DOI Listing

Association Between Abdominal Waist Circumference and Blood Pressure In Brazilian Adolescents With Normal Body Mass Index: Waist circumference and blood pressure in Adolescents.

Glob Heart 2020 Apr 3;15(1):27. Epub 2020 Apr 3.

Center for Clinical and Epidemiological Research (EpiCenter), School of Medicine, Pontifícia Universidade Católica do Paraná, Rua Rockfeller, Curitiba/PR, BR.

Obesity is the most common chronic disease in adolescents. In adults, waist circumference (WC) is associated with the presence of cardiovascular risk factors and is also a better predictor of cardiovascular (CV) risk than body mass index (BMI). The association between WC and CV risk factors in adolescents has been poorly explored so far, mainly in those within the normal BMI range. Read More

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http://dx.doi.org/10.5334/gh.779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218763PMC

Prevalence of Combined Lipid Abnormalities in Brazilian Adolescents and Its Association with Nutritional Status: Data from the Erica Study.

Glob Heart 2020 Mar 18;15(1):23. Epub 2020 Mar 18.

Pontificial Catholic University of Parana (PUCPR), Curitiba, BR.

Background: Cardiovascular diseases are the leading cause of death in Brazil and worldwide. The growing incidence of obesity in children and adolescents and its association with lipid abnormalities may worsen this scenario, mainly in developing countries where obesity has reached epidemic levels. Dyslipidemias have several patterns, and the combination of some lipid abnormalities may have higher atherogenic potential. Read More

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http://dx.doi.org/10.5334/gh.769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218779PMC

Cost-Effectiveness of Rheumatic Heart Disease Echocardiographic Screening in Brazil: Data from the PROVAR+ Study: Cost-effectiveness of RHD screening in Brazil.

Glob Heart 2020 Feb 20;15(1):18. Epub 2020 Feb 20.

Serviço de Cardiologia e Cirurgia Cardiovascular e Centro de Telessaúde, Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, MG, BR.

Introduction: In recent years, new technologies - noticeably ultra-portable echocardiographic machines - have emerged, allowing for Rheumatic Heart Disease (RHD) early diagnosis. We aimed to perform a cost-utility analysis to assess the cost-effectiveness of RHD screening with handheld devices in the Brazilian context.

Methods: A Markov model was created to assess the cost-effectiveness of one-time screening for RHD in a hypothetical cohort of 11-year-old socioeconomically disadvantaged children, comparing the intervention to standard care using a public perspective and a 30-year time horizon. Read More

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http://dx.doi.org/10.5334/gh.529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218764PMC
February 2020

Portuguese-Brazilian evidence-based guideline on the management of hyperglycemia in type 2 diabetes mellitus.

Diabetol Metab Syndr 2020 24;12:45. Epub 2020 May 24.

Internal Medicine Department, School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Rua Ramiro Barcelos, 2350, 4º Andar, Porto Alegre, RS 90035-007 Brazil.

Background: In current management of type 2 diabetes (T2DM), cardiovascular and renal prevention have become important targets to be achieved. In this context, a joint panel of four endocrinology societies from Brazil and Portugal was established to develop an evidence-based guideline for treatment of hyperglycemia in T2DM.

Methods: MEDLINE (via PubMed) was searched for randomized clinical trials, meta-analyses, and observational studies related to diabetes treatment. Read More

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http://dx.doi.org/10.1186/s13098-020-00551-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245758PMC

Bellwether Procedures for Monitoring Subnational Variation of All-cause Perioperative Mortality in Brazil.

World J Surg 2020 Jun 2. Epub 2020 Jun 2.

Deakin University and Barwon Health, Melbourne, Australia.

Background: All-cause perioperative mortality rate (POMR) is a commonly reported metric to assess surgical quality. Benchmarking POMR remains difficult due to differences in surgical volume and case mix combined with the burden of reporting and leveraging this complex and high-volume data. We seek to determine whether the pooled and individual procedure POMR of each bellwether (cesarean section, laparotomy, management of open fracture) correlate with state-level all-cause POMR in the interest of identifying benchmark procedures that can be used to make standardized regional comparisons of surgical quality. Read More

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http://dx.doi.org/10.1007/s00268-020-05607-xDOI Listing

Organizational factors associated with adherence to low tidal volume ventilation: a secondary analysis of the CHECKLIST-ICU database.

Ann Intensive Care 2020 Jun 1;10(1):68. Epub 2020 Jun 1.

Department of Critical Care Medicine, Hospital Israelita Albert Einstein, Albert Einstein Avenue, 700, São Paulo, Brazil.

Background: Survival benefit from low tidal volume (V) ventilation (LTVV) has been demonstrated for patients with acute respiratory distress syndrome (ARDS), and patients not having ARDS could also benefit from this strategy. Organizational factors may play a role on adherence to LTVV. The present study aimed to identify organizational factors with an independent association with adherence to LTVV. Read More

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http://dx.doi.org/10.1186/s13613-020-00687-3DOI Listing

Validation and cultural translation for the Brazilian Portuguese version of the Questionnaire for Urinary Incontinence Diagnosis.

Int Urogynecol J 2020 Jun 2. Epub 2020 Jun 2.

Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas (UNICAMP), Rua Alexander Fleming, 101, Cidade Universitária, Campinas, SP, 13083-881, Brazil.

Introduction And Hypothesis: Short questionnaires are important for validating the clinical diagnosis of urinary incontinence (UI). We sought to validate and culturally translate the Questionnaire for Urinary Incontinence Diagnosis (QUID) for the Brazilian Portuguese language.

Methods: A cross-sectional study with 457 women (330 with urinary incontinence and 127 controls) was performed in a Southeastern Brazilian outpatient clinic. Read More

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http://dx.doi.org/10.1007/s00192-020-04344-yDOI Listing

Pore-scale investigation of the use of reactive nanoparticles for in situ remediation of contaminated groundwater source.

Proc Natl Acad Sci U S A 2020 Jun 2. Epub 2020 Jun 2.

Brazilian Synchrotron Light Laboratory, Brazilian Center for Research in Energy and Materials, 13083-970 Campinas, São Paulo, Brazil.

Nanoscale zero-valent iron (nZVI) particles have excellent capacity for in situ remediation of groundwater resources contaminated by a range of organic and inorganic contaminants. Chlorinated solvents are by far the most treated compounds. Studies at column, pilot, and field scales have reported successful decrease in contaminant concentration upon injection of nZVI suspensions in the contaminated zones. Read More

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http://dx.doi.org/10.1073/pnas.1918683117DOI Listing