150 results match your criteria Brain tumor research and treatment[Journal]


Pheochromocytoma with Brain Metastasis: A Extremely Rare Case in Worldwide.

Brain Tumor Res Treat 2018 Oct;6(2):101-104

Department of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Pheochromocytoma (PCC) is a neuroendocrine tumor that mainly arises from the medulla of the adrenal gland. Some PCCs become malignant and metastasize to other organs. For example, it typically involves skeletal system, liver, lung, and regional lymph nodes. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.14791/btrt.2018.
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http://dx.doi.org/10.14791/btrt.2018.6.e18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212688PMC
October 2018
9 Reads

Metaplastic Meningioma Overspreading the Cerebral Convexity.

Brain Tumor Res Treat 2018 Oct;6(2):97-100

Department of Pathology, Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, Korea.

Meningioma is relatively common, benign, and extra-axial tumor accounting for about 20% of primary brain and spinal cord tumors. The World Health Organization (WHO) classified these tumors into Grade I (benign), Grade II (atypical), and Grade III (anaplastic) meningioma. Grade I meningioma which is slowly growing tumor and have some rare subtypes. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212693PMC
October 2018
5 Reads

Brain Abscess Showing a Lack of Restricted Diffusion and Successfully Treated with Linezolid.

Brain Tumor Res Treat 2018 Oct;6(2):92-96

Department of Neurosurgery, Eulji University, Nowon Eulji Medical Center, Seoul, Korea.

A 59-year-old patient with a history of hepatocellular carcinoma presented with decreased consciousness and left hemiparesis. A rim-enhanced mass lesion without diffusion restriction was observed in contrast-enhanced MRI including diffusion-weighted imaging. Based on these findings, metastatic brain tumor was suspected. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212685PMC
October 2018
14 Reads

Secondary Aneurysmal Bone Cyst in a Craniofacial Fibrous Dysplasia: Case Report.

Brain Tumor Res Treat 2018 Oct;6(2):86-91

Department of Neurosurgery, Konkuk University Medical Center, Seoul, Korea.

Aneurysmal bone cyst (ABC) is a rare non-neoplastic bone lesion that involves mostly the long bones and vertebrae and may occur very rarely in the craniofacial bones. ABCs may occur as secondary bony pathologies in association with various benign and malignant bone tumors and with fibrous dysplasia (FD). FD is a common non-neoplastic bony pathology mostly affecting craniofacial bones. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212691PMC
October 2018
2 Reads

Giant Sellar Xanthogranuloma after Surgical Treatment of Symptomatic Rathke's Cleft Cyst.

Brain Tumor Res Treat 2018 Oct;6(2):82-85

Department of Pathology, Kosin University Gospel Hospital, Busan, Korea.

Extremely massive sellar xanthogranuloma (XG) are rare, and the surgical outcome and prognosis are not well known. XG remain unknown whether they are derived from Rathke's cleft cysts (RCCs) or craniopharyngiomas (CPs) following extensive inflammation and metaplasia, to the point that no epithelium is readily identifiable. These lesions usually tend to occur in younger patients (mean 28. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212686PMC
October 2018
9 Reads

Gliosarcoma of Cerebello-Pontine Angle: A Case Report and Review of the Literature.

Brain Tumor Res Treat 2018 Oct;6(2):78-81

Department of Neurosurgery, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.

Gliosarcoma (GS), known as variant of glioblastoma multiforme, is aggressive and very rare primary central nervous system malignant neoplasm. They are usually located in the supratentorial area with possible direct dural invasion or only reactive dural thickening. However, in this case, GS was located in lateral side of left posterior cranial fossa. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.14791/btrt.2018.
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http://dx.doi.org/10.14791/btrt.2018.6.e11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212687PMC
October 2018
1 Read

Pineal and Suprasellar Germinoma Cooccurence with Vertebra Plana: A Case Report.

Brain Tumor Res Treat 2018 Oct;6(2):73-77

Department of Neurosurgery, Mashhad University of Medical Sciences, Mashhad, Iran.

Germinoma is the most common type of intracranial germ cell tumors (GCTs). Pineal gland and suprasellar region are the most frequent sites of central nervous system (CNS) involvement. Intracranial masses caused by Langerhans cell histiocytosis (LCH) mimics features of CNS GCTs. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.14791/btrt.2018.
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http://dx.doi.org/10.14791/btrt.2018.6.e9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212690PMC
October 2018
6 Reads

Arachnoid Granulations Mimicking Multiple Osteolytic Bone Lesions in the Occipital Bone.

Brain Tumor Res Treat 2018 Oct;6(2):68-72

Department of Neurosurgery, Kyungpook National University School of Medicine, Kyungpook National University Hospital, Daegu, Korea.

We report a rare case of arachnoid granulations mimicking multiple osteolytic bone lesions. A 66-year-old woman was admitted to a local clinic for a regular checkup. Upon admission, brain CT showed multiple osteolytic lesions in the occipital bone. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.14791/btrt.2018.
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http://dx.doi.org/10.14791/btrt.2018.6.e8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212694PMC
October 2018
14 Reads

Surgical Outcomes of Thalamic Tumors in Children: The Importance of Diffusion Tensor Imaging, Neuro-Navigation and Intraoperative Neurophysiological Monitoring.

Brain Tumor Res Treat 2018 Oct;6(2):60-67

Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Background: Recently, modern technology such as diffusion tensor imaging (DTI), neuro-navigation and intraoperative neurophysiological monitoring (IOM) have been actively adopted for the treatment of thalamic tumors. We evaluated surgical outcomes and efficacy of the aforementioned technologies for the treatment of pediatric thalamic tumors.

Methods: We retrospectively reviewed clinical data from 37 children with thalamic tumors between 2004 and 2017. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.14791/btrt.2018.
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http://dx.doi.org/10.14791/btrt.2018.6.e14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212692PMC
October 2018
2 Reads

A Retrospective Analysis of the Clinical Outcomes of Leptomeningeal Metastasis in Patients with Solid Tumors.

Brain Tumor Res Treat 2018 Oct;6(2):54-59

Department of Internal Medicine, Kosin University Gaspel Hospital, Busan, Korea.

Background: Leptomeningeal metastasis (LM) is an uncommon, but devastating complication of advanced cancer and has no standard treatment. Herein, we analyzed the clinical characteristics and outcomes of patients with solid tumors who were diagnosed with LM.

Methods: Between January 2007 and December 2017, we retrospectively analyzed the medical records of patients with solid tumors who were diagnosed with LM. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212684PMC
October 2018
4 Reads

Current Radiopharmaceuticals for Positron Emission Tomography of Brain Tumors.

Brain Tumor Res Treat 2018 Oct;6(2):47-53

Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Korea.

Brain tumors represent a diverse spectrum of histology, biology, prognosis, and treatment options. Although MRI remains the gold standard for morphological tumor characterization, positron emission tomography (PET) can play a critical role in evaluating disease status. This article focuses on the use of PET with radiolabeled glucose and amino acid analogs to aid in the diagnosis of tumors and differentiate between recurrent tumors and radiation necrosis. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212689PMC
October 2018
13 Reads

Extensive Pituitary Apoplexy after Chemotherapy in a Patient with Metastatic Breast Cancer.

Brain Tumor Res Treat 2018 Apr;6(1):43-46

Department of Cancer Control, National Cancer Center, Graduate School of Cancer Science and Policy, Goyang, Korea.

Surgery, anticoagulation therapy, pregnancy, and hormone treatments, such as bromocriptine, are well-characterized precipitating factors for pituitary apoplexy. However, whether cytotoxic chemotherapy for systemic cancer could cause pituitary apoplexy has not been investigated. Here, we present a case of a 41-year-old woman who developed a severe headache with decreased visual acuity after intravenous cytotoxic chemotherapy to treat metastatic breast cancer. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932299PMC
April 2018
4 Reads

Intermediate Pilomyxoid Astrocytoma in the Cerebellum of a 5-Year-Old Boy.

Brain Tumor Res Treat 2018 Apr;6(1):39-42

Department of Neurosurgery, Wonkwang University Hospital, Iksan, Korea.

Intermediate pilomyxoid tumors (IPTs) were defined by the presence of some features typical of pilomyxoid astrocytoma (PMA) in combination with features that could be considered more consistent with pilocytic astrocytoma (PA). PMA is rare in the cerebellum. And, IPT in the cerebellum is rarer than PMA. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932298PMC
April 2018
13 Reads

Mitochondrial 10398A>G NADH-Dehydrogenase Subunit 3 of Complex I Is Frequently Altered in Intra-Axial Brain Tumors in Malaysia.

Brain Tumor Res Treat 2018 Apr;6(1):31-38

Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, Kelantan, Malaysia.

Background: Mitochondria are major cellular sources of reactive oxygen species (ROS) generation which can induce mitochondrial DNA damage and lead to carcinogenesis. The mitochondrial 10398A>G alteration in NADH-dehydrogenase subunit 3 (ND3) can severely impair complex I, a key component of ROS production in the mitochondrial electron transport chain. Alteration in ND3 10398A>G has been reported to be linked with diverse neurodegenerative disorders and cancers. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932297PMC
April 2018
2 Reads

Risk of Brain Tumor Induction from Pediatric Head CT Procedures: A Systematic Literature Review.

Brain Tumor Res Treat 2018 Apr;6(1):1-7

Department of Neurosurgery, David Geffen School of Medicine of the University of California, Los Angeles (UCLA), Los Angeles, CA, USA.

Head computed tomography (CT) is instrumental for managing patients of all ages. However, its low dose radiation may pose a low but non-zero risk of tumor induction in pediatric patients. Here, we present a systematic literature review on the estimated incidence of brain tumor induction from head CT exams performed on children and adolescents. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932294PMC

Cystic Meningiomas: Correlation between Radiologic and Histopathologic Features.

Brain Tumor Res Treat 2018 Apr 2;6(1):13-21. Epub 2018 Apr 2.

Department of Neurosurgery, Gyeongsang National University Hospital, Jinju, Korea.

Background: Tumors with cysts often correlate with gliomas, metastatic tumors, or hemangioblastomas, which require differentiation.

Methods: Thirty-eight cases of cyst associated-meningioma based on preoperative radiologic studies and histologic confirmations were reviewed from November 1998 to July 2017.

Results: A total of 395 cases of meningioma were observed in the 20 years, and surgical treatment of intracranial meningioma was performed in 120 cases. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932295PMC
April 2018
10 Reads

Optic Nerve Sheath Meningioma: Preliminary Analysis of the Role of Radiation Therapy.

Brain Tumor Res Treat 2018 Apr 2;6(1):8-12. Epub 2018 Apr 2.

Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, Korea.

Background: The purpose of this study was to evaluate the treatment outcome of our optic nerve sheath meningioma (ONSM) case series in terms of preventing tumor growth and preserving vision in ONSM patients.

Methods: Between July 2003 and March 2015, 1,398 patients with intracranial meningioma were diagnosed at Seoul National University Bundang Hospital. Among them, only 13 patients (0. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932300PMC
April 2018
10 Reads

Prognostic Evaluation of Neurological Assessment of the Neuro-Oncology Scale in Glioblastoma Patients.

Brain Tumor Res Treat 2018 Apr 2;6(1):22-30. Epub 2018 Apr 2.

Division of Neuro-Oncology and Department of Neurosurgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.

Background: The aims of this study were to investigate the role of the Neurological Assessment of Neuro-Oncology (NANO) scale in predicting the prognosis of patients with glioblastoma, and compare these results to predicted data of the Karnofsky Performance Scale (KPS), and Eastern Cooperative Oncology Group (ECOG)/World Health Organization (WHO) performance status. Additionally, we examined other prognostic factors in glioblastoma patients.

Methods: The medical records of 76 patients with a new diagnosis of histologically ascertained glioblastoma in the period from January 2002 to December 2015 at the authors' institution were retrospectively reviewed. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932296PMC
April 2018
1 Read

Extra-Axial and Clear Cell Type Ependymoma, Mimicking a Convexity Meningioma.

Brain Tumor Res Treat 2017 Oct 31;5(2):127-130. Epub 2017 Oct 31.

Department of Neurosurgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Koera.

A 33-year-old woman presented with tingling and paresthesia on left extremity for 2 months. Magnetic resonance imaging revealed that the tumor was iso- and hypo-intensity on T1-weighted image, mixed iso- and high-signal intensity on T2-weighted images and heterogeneously enhanced with rim enhancement. Neither arachnoid cleft nor dural tail was certain but mass was located extra-axially so meningioma was suspected. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.2.127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700026PMC
October 2017
6 Reads

Astroblastoma in a Young Female Patient: A Case Report and Literature Review of Clinicopathological, Radiological and Prognostic Characteristics and Current Treatment Strategies.

Brain Tumor Res Treat 2017 Oct 31;5(2):120-126. Epub 2017 Oct 31.

Center for Nuclear Medicine and Radiotherapy, Quetta, Pakistan.

Astroblastoma is an uncommon glial tumor with predominant manifestation in the young age. Herein, we report a case of 18-year-old astroblastoma female patient who presented with history of two months headache. Magnetic resonance imaging (MRI) of the brain demonstrated well circumscribed, intra-axial abnormal signal intensity lesion (size=5×4 cm) in the right parieto-occipital region of the brain. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.14791/btrt.2017.
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http://dx.doi.org/10.14791/btrt.2017.5.2.120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700025PMC
October 2017
4 Reads

Subfrontal Schwannoma Extended Broadly to Nasal Cavity Treated by Gamma Knife Radiosurgery Following Surgical Excision: A Case Report.

Brain Tumor Res Treat 2017 Oct 31;5(2):116-119. Epub 2017 Oct 31.

Department of Neurosurgery, Pusan National University Hospital, Busan, Korea.

Subfrontal schwannomas are rarely reported. They are usually found only in the subfrontal area, but some extend to the nasal cavity. In these cases, prevention of postoperative cerebrospinal fluid (CSF) leakage through thinned or eroded anterior skull base is important. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.2.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700024PMC
October 2017
2 Reads

Pituicytoma with Significant Tumor Vascularity Mimicking Pituitary Macroadenoma.

Brain Tumor Res Treat 2017 Oct 31;5(2):110-115. Epub 2017 Oct 31.

Department of Pathology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.

A 19-year-old man presented with bitemporal hemianopsia and was found to have a large sellar and suprasellar tumor, resembling a pituitary macroadenoma. Emergency transsphenoidal approach was attempted because of rapid visual deterioration with headache. However, the approach was complicated and stopped by uncontrolled hemorrhage from the tumor. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.2.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700023PMC
October 2017
6 Reads

Supratentorial Pilocytic Astrocytoma Mimicking Convexity Meningioma with Early Anaplastic Transformation: A Case Report.

Brain Tumor Res Treat 2017 Oct 31;5(2):105-109. Epub 2017 Oct 31.

Department of Neurosurgery, Pusan National University Hospital, Busan, Korea.

Meningiomas and pilocytic astrocytomas are benign intracranial tumors. Pilocytic astrocytomas arises frequently at the posterior fossa in childhood. Meningiomas have several image findings, such as a dural tail sign, bony erosion, and sunburst appearance on angiography. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.2.105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700022PMC
October 2017
2 Reads

Response of Leptomeningeal Dissemination of Anaplastic Glioma to Temozolomide: Experience of Two Cases.

Brain Tumor Res Treat 2017 Oct 31;5(2):99-104. Epub 2017 Oct 31.

Department of Cancer Biomedical Science, National Cancer Center, Graduate School of Cancer Science and Policy, Goyang, Korea.

The incidence of leptomeningeal dissemination (LMD) of anaplastic glioma has been increasing. LMD can be observed at the time of initial presentation or the time of recurrence. As a result of both rarity and unusual presentation, a standard therapy has not yet been suggested. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.2.99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700034PMC
October 2017
6 Reads

Pituitary Ependymoma, 10-Year Follow-Up after Partial Resection and Radiation Therapy.

Brain Tumor Res Treat 2017 Oct 31;5(2):94-98. Epub 2017 Oct 31.

Neuro-Oncology Clinic, National Cancer Center, Goyang, Korea.

Ependymoma usually arises within the ventricles and central canal of the spinal cord. These tumors, found in the sellar region, are extremely rare. We report a case of pituitary ependymoma followed up over 10 years. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.2.94DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700033PMC
October 2017
3 Reads

Outcomes in 20 Gynecologic Cancer Patient with Brain Metastasis: A Single Institution Retrospective Study.

Brain Tumor Res Treat 2017 Oct 31;5(2):87-93. Epub 2017 Oct 31.

Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, Korea.

Background: The incidence of brain metastasis (BM) in gynecologic cancers has risen recently, due to prolonged survival times and an early diagnosis. We analyzed treatment outcomes of patients with BM from gynecologic cancers.

Methods: Among 951 patients with BM who were treated in neurosurgical department from July 2003 to February 2016, a total of 20 (2%) patients were from gynecologic cancers. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.2.87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700032PMC
October 2017
9 Reads

The Clinical Outcome of Hydroxyurea Chemotherapy after Incomplete Resection of Atypical Meningiomas.

Brain Tumor Res Treat 2017 Oct 31;5(2):77-86. Epub 2017 Oct 31.

Division of Neuro-Oncology and Department of Neurosurgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.

Background: The aim of this study is to investigate the clinical results of adjuvant chemotherapy with hydroxyurea and to compare those with the results of postoperative radiotherapy after incomplete resection of atypical meningiomas (ATMNGs).

Methods: We retrospectively reviewed the medical records of 84 patients with ATMNGs diagnosed in the period from January 2000 to December 2014. Clinical data included patient sex and age at the time of surgery, presenting symptoms at diagnosis, location and size of tumor, extent of surgery, use of postoperative radiotherapy or hydroxyurea chemotherapy, duration of follow-up, and progression. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.2.77DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700031PMC
October 2017
2 Reads

Ependymomas: Prognostic Factors and Outcome Analysis in a Retrospective Series of 33 Patients.

Brain Tumor Res Treat 2017 Oct 31;5(2):70-76. Epub 2017 Oct 31.

Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital & Medical School, Hwasun, Korea.

Background: The purpose of this study was to evaluate the prognostic factors and outcomes in patients with ependymoma to management plans.

Methods: Between 1997 and 2013, 33 patients with 25 ependymomas (WHO grade II) and eight anaplastic ependymomas (WHO grade III) were pathologically diagnosed. Six were pediatric patients (mean age, 6. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.2.70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700030PMC
October 2017
5 Reads

Genomic and Molecular Characterization of Brain Tumors in Asian and Non-Asian Patients of Los Angeles: A Single Institution Analysis.

Brain Tumor Res Treat 2017 Oct 31;5(2):64-69. Epub 2017 Oct 31.

Department of Neurosurgery, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA, USA.

Background: Worldwide, approximately 2% of new cancers are of the brain. Five-year survival rates among brain cancer patients have been reported as a little over a third. Differences in clinical outcomes between brain tumor patients of different races remain poorly understood. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.14791/btrt.2017.
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http://dx.doi.org/10.14791/btrt.2017.5.2.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700029PMC
October 2017
7 Reads

Recurred Intracranial Meningioma: A Retrospective Analysis for Treatment Outcome and Prognostic Factor.

Brain Tumor Res Treat 2017 Oct 3;5(2):54-63. Epub 2017 Nov 3.

Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital & Medical School, Hwasun, Korea.

Background: In this study, we aimed to compare repeated resection and radiation treatment, such as Gamma knife radiosurgery (GKRS) or conventional radiotherapy (RT), and investigate the factors influencing treatment outcome, including overall survival (OS), progression-free survival (PFS), and complication rates.

Methods: We retrospectively reviewed 67 cases of recurred intracranial meningiomas (repeated resection: 36 cases, radiation treatment: 31 cases) with 56 months of the median follow-up duration (range, 13-294 months).

Results: The incidence of death rate was 29. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.2.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700028PMC
October 2017
8 Reads

Greetings from the New Editor-in-Chief.

Authors:
Jeong-Hyun Hwang

Brain Tumor Res Treat 2017 Oct 31;5(2):53. Epub 2017 Oct 31.

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http://dx.doi.org/10.14791/btrt.2017.5.2.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700027PMC
October 2017

A Case of Coincidental Intrasellar Chordoma and Pituitary Adenoma.

Brain Tumor Res Treat 2017 Apr 30;5(1):49-52. Epub 2017 Apr 30.

Department of Neurosurgery, School of Medicine, Kyungpook National University, Daegu, Korea.

Although chordomas are midline tumors, primarily intrasellar chordomas are extremely rare. In this report, the authors describe the case of a 68-year-old female with partial abducens nerve palsy in the right eye due to the intrasellar cystic tumor. After endonasal trans-sphenoidal surgery, intraoperative and histopathological findings confirmed the co-occurrence of an entirely intrasellar chordoma and pituitary adenoma. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.1.49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433953PMC
April 2017
21 Reads

Cutaneous Anaplastic Large T-Cell Lymphoma with Invasion of the Central Nervous System: A Case Report.

Brain Tumor Res Treat 2017 Apr 30;5(1):45-48. Epub 2017 Apr 30.

Department of Neurosurgery, Konyang University Hospital, Daejeon, Korea.

Anaplastic large T-cell lymphoma (ALCL) encompasses different clinical entities that can be aggressive or localized. Scalp anaplastic lymphoma kinase (ALK)-negative ALCL is considered a localized lymphoma, and usually extends to the regional lymph nodes; intracranial invasion is rare. A 74-year-old woman was diagnosed with scalp ALK-negative ALCL, but did not exhibit invasion of the lymph nodes. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.1.45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433952PMC
April 2017
35 Reads

Fourth Ventricle Neurenteric Cyst Mimicking Hemangioblastoma.

Brain Tumor Res Treat 2017 Apr 30;5(1):42-44. Epub 2017 Apr 30.

Seoul National University College of Medicine, Seoul, Korea.

This report presents a case of fourth ventricle neurenteric cyst (NE cyst) mimicking hemangioblastoma, which developed in a 50-year-old woman. A tiny enhancing mural portion of the fourth ventricle in MRI suggested that the cyst was hemangioblastoma, but pathological evidence showed that the cyst was in fact NE cyst in the fourth ventricle. In order to make proper decision on to what extent of surgical resection should be done, considering every possibility in differential diagnosis might be helpful. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.1.42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433951PMC
April 2017
1 Read

Subependymal Giant Cell Astrocytoma Presenting with Tumoral Bleeding: A Case Report.

Brain Tumor Res Treat 2017 Apr 30;5(1):37-41. Epub 2017 Apr 30.

Department of Radiology, Chonnam National University Medical School, Chonnam National University Hwasun Hospital, Hwasun, Korea.

We report a rare case of subependymal giant cell astrocytoma (SEGA) associated with tumoral bleeding in a pediatric patient without tuberous sclerosis complex (TSC). A 10-year-old girl presented with a 2-week history of an increasingly aggravating headache. Brain magnetic resonance imaging revealed an approximately 3. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.1.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433950PMC
April 2017
24 Reads

Toxoplasmic Encephalitis in Patient with Acquired Immunodeficiency Syndrome.

Brain Tumor Res Treat 2017 Apr 30;5(1):34-36. Epub 2017 Apr 30.

Department of Neurosurgery, Uijeongbu St. Mary's Hospital, The Catholic University of Korea School of Medicine, Uijeongbu, Korea.

Toxoplasmic encephalitis (TE) is an opportunistic infection found in immunocompromised patients and TE related cerebral mass lesion is often reported in acquired immunodeficiency acquired immunodeficiency syndrome (AIDS) patients. However, incidence of TE related AIDS in Korea is still rare and is unfamiliar to neurosurgeons. Differential diagnosis is needed to rule out other brain lesions. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.1.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433949PMC
April 2017
11 Reads

Primary Central Nervous System Vasculitis Mimicking a Cortical Brain Tumor: A Case Report.

Brain Tumor Res Treat 2017 Apr 30;5(1):30-33. Epub 2017 Apr 30.

Department of Radiology, Chonnam National University Medical School, Chonnam National University Hwasun Hospital, Hwasun, Korea.

We report a case of primary central nervous system vasculitis (PCNSV) mimicking a cortical brain tumor. A 25-year-old woman presented with a 2-week history of headache and transient right hemiparesis. Brain magnetic resonance imaging (MRI) revealed a cortical-involving lesion on the left frontal lobe. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.1.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433948PMC
April 2017
17 Reads

Fourth Ventricular Lesions in Metastatic Gliomas: A Rare Predilection?

Brain Tumor Res Treat 2017 Apr 30;5(1):24-29. Epub 2017 Apr 30.

Department of Radiology, University of Manitoba, Winnipeg, Canada.

Over the course of five years, a total of ten cases were collected of glioma patients in whom a distant lesion at the fourth ventricle was noted. A 'distant lesion' was defined as a lesion with a normal appearing tissue bridge at imaging between the primary and secondary locations. Previous imaging of these patients was reviewed along with clinical history, course of therapy, and available histology. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.1.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433947PMC
April 2017
14 Reads

An Updated Nationwide Epidemiology of Primary Brain Tumors in Republic of Korea, 2013.

Brain Tumor Res Treat 2017 Apr 30;5(1):16-23. Epub 2017 Apr 30.

Neuro-Oncology Clinic, National Cancer Center, Goyang, Korea.

Background: This report aims to provide accurate nationwide epidemiologic data on primary brain and central nervous system (CNS) tumors in the Republic of Korea. We updated the data by analyzing primary brain and CNS tumors diagnosed in 2013 using the data from the national cancer incidence database.

Methods: Data on primary brain and CNS tumors diagnosed in 2013 were collected from the Korean Central Cancer Registry. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.1.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433946PMC
April 2017
38 Reads

Systematic Analysis of Clinical Outcomes Following Stereotactic Radiosurgery for Central Neurocytoma.

Brain Tumor Res Treat 2017 Apr 30;5(1):10-15. Epub 2017 Apr 30.

Department of Neurosurgery, University of California, Los Angeles, CA, USA.

Central neurocytoma (CN) typically presents as an intraventricular mass causing obstructive hydrocephalus. The first line of treatment is surgical resection with adjuvant conventional radiotherapy. Stereotactic radiosurgery (SRS) was proposed as an alternative therapy for CN because of its lower risk profile. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.1.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433945PMC
April 2017
10 Reads

Bevacizumab in Recurrent Glioma: Patterns of Treatment Failure and Implications.

Brain Tumor Res Treat 2017 Apr 30;5(1):1-9. Epub 2017 Apr 30.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.

Glioblastoma, the most common primary malignant brain tumor in adults, is highly aggressive and associated with a poor prognosis. Bevacizumab, a monoclonal antibody against the vascular endothelial growth factor receptor, has increasingly been used in the treatment of recurrent glioblastoma. It has achieved excellent rates of radiographic response, but most patients will progress after only a few months. Read More

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http://dx.doi.org/10.14791/btrt.2017.5.1.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433944PMC
April 2017
8 Reads

Seeding of Meningeal Sarcoma Along a Surgical Trajectory on the Scalp.

Brain Tumor Res Treat 2016 Oct 31;4(2):160-163. Epub 2016 Oct 31.

Department of Neurosurgery, Incheon St. Mary's Hospital, The Catholic University of Korea, Incheon, Korea.

Primary sarcomas of the central nervous system are rare. These tumors is rapid growth often produces mass effect on the brain. Diagnosis is rendered pathologically after resection. Read More

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http://dx.doi.org/10.14791/btrt.2016.4.2.160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114191PMC
October 2016

A Case of Primary Central Nervous System Lymphoma Located at Brain Stem in a Child.

Brain Tumor Res Treat 2016 Oct 31;4(2):155-159. Epub 2016 Oct 31.

Division of Neurooncology and Department of Neurosurgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.

Primary central nervous system lymphoma (PCNSL) is an extranodal Non-Hodgkin's lymphoma that is confined to the brain, eyes, and/or leptomeninges without evidence of a systemic primary tumor. Although the tumor can affect all age groups, it is rare in childhood; thus, its incidence and prognosis in children have not been well defined and the best treatment strategy remains unclear. A nine-year old presented at our department with complaints of diplopia, dizziness, dysarthria, and right side hemiparesis. Read More

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http://dx.doi.org/10.14791/btrt.2016.4.2.155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114190PMC
October 2016

Comparison of 3 and 7 Tesla Magnetic Resonance Imaging of Obstructive Hydrocephalus Caused by Tectal Glioma.

Brain Tumor Res Treat 2016 Oct 31;4(2):150-154. Epub 2016 Oct 31.

Medical Neuroscience and Neurosurgery, Chungbuk National University Hospital, Cheongju, Korea.; Department of Neurosurgery, Chungbuk National University Hospital, Cheongju, Korea.

Obstructive hydrocephalus caused by tectal glioma, which relived by neuroendoscopy, have been described using 3.0 Tesla magnetic resonance imaging (3T MRI) so far, we present the results obtained from 3T and 7T MRI in this patient. A 21-year-old woman presented at our hospital with gait disturbance, hormonal insufficiency, and urinary incontinence that began prior to 6 years of age. Read More

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http://dx.doi.org/10.14791/btrt.2016.4.2.150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114189PMC
October 2016
12 Reads

World Health Organization Grade II Oligodendroglioma Occurring after Successful Treatment for Childhood Acute Lymphoblastic Leukemia.

Brain Tumor Res Treat 2016 Oct 31;4(2):145-149. Epub 2016 Oct 31.

Department of Neurosurgery, Korea University Anam Hospital, College of Medicine, Korea University, Seoul, Korea.

When treating childhood acute lymphoblastic leukemia (ALL), secondary neoplasms are a significant long term problem. Radiation is generally accepted to be a major cause of the development of secondary neoplasms. Following treatment for ALL, a variety of secondary tumors, including brain tumors, hematologic malignancies, sarcomas, thyroid cancers, and skin cancers have been reported. Read More

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http://dx.doi.org/10.14791/btrt.2016.4.2.145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114188PMC
October 2016
7 Reads

Multiple Meningocerebral Metastasis and Extensive Skull Metastasis from Squamous Cell Carcinoma of Esophagus: A Case Report and Review of Literature.

Brain Tumor Res Treat 2016 Oct 31;4(2):142-144. Epub 2016 Oct 31.

Department of Neurosurgery, Hanyang University Guri Hospital, Guri, Korea.

Esophageal carcinoma rarely metastasizes to the brain. Although some studies have mentioned esophageal cancer with solitary brain metastasis or with meningocerebral metastasis or with skull metastasis, multiple meningocerebral metastasis and extensive skull metastasis from squamous cell carcinoma of esophagus has not been reported in the literature. We encountered a case of an extensive osteolytic change of the skull and multiple meningocerebral metastases from esophageal carcinoma. Read More

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http://dx.doi.org/10.14791/btrt.2016.4.2.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114187PMC
October 2016
6 Reads

A Case of Solitary Brain Metastasis from Uterine Mullerian Adenosarcoma with Sarcomatous Overgrowth.

Brain Tumor Res Treat 2016 Oct 31;4(2):138-141. Epub 2016 Oct 31.

Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea.

Uterine adenosarcoma (AS) are rare tumors and have more favorable outcomes than the aggressive uterine carcinosarcomas. Uterine adenosarcoma with sarcomatous overgrowth (ASSO) is a variant form of AS and exhibits aggressive growth of tumor and the prognosis is relatively poor compared with typical AS. Usually patterns of metastasis have been known to behave like endometrial carcinoma and spread through the lymphatics. Read More

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http://dx.doi.org/10.14791/btrt.2016.4.2.138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114186PMC
October 2016
31 Reads

A Stable Secondary Gliosarcoma with Extensive Systemic Metastases: A Case Report.

Brain Tumor Res Treat 2016 Oct 31;4(2):133-137. Epub 2016 Oct 31.

Department of Pathology, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital & Medical School, Gwangju, Korea.

A 63-year-old man complained of intermittent motor weakness of his arm. The magnetic resonance image (MRI) of his brain displayed a high signal lesion in right cingulate gyrus on T2 weighted image. One year later, he showed a stuporous mental status with repeated seizures, and the follow-up brain MRI showed heterogeneously enhanced mass associated with bleeding. Read More

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http://dx.doi.org/10.14791/btrt.2016.4.2.133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114185PMC
October 2016

Metastatic Intracranial Hemangiopericytoma to the Spinal Column: A Case Report.

Brain Tumor Res Treat 2016 Oct 31;4(2):128-132. Epub 2016 Oct 31.

Department of Pathology, Konkuk University Medical Center, Seoul, Korea.

Intracranial hemangiopericytoma (HPC) is a rare brain tumor with aggressive biologic behavior associated with high recurrence rate and often with extracranial metastasis. The most common sites of extracranial metastasis of the intracranial HPC are the long bones, lung, liver and abdominal cavity in the order of frequencies. Extracranial metastases usually occur long after the initial diagnosis of the primary tumor. Read More

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http://dx.doi.org/10.14791/btrt.2016.4.2.128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114184PMC
October 2016
1 Read

Failed First Craniotomy and Tumor Removal of Parasagittal Meningioma with Severe Peritumoral Brain Edema.

Brain Tumor Res Treat 2016 Oct 31;4(2):124-127. Epub 2016 Oct 31.

Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.; Department of Neurosurgery, SMG-Seoul National University Boramae Medical Center, Seoul, Korea.

Parasagittal meningioma often presents as peritumoral brain edema (PTBE). The risk of edema increases when the tumor occludes the superior sagittal sinus (SSS). Although PTBE may be expected based on the patient's symptoms or radiologic findings, extensive brain swelling and extracranial herniation during elective surgery are rare. Read More

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http://dx.doi.org/10.14791/btrt.2016.4.2.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114183PMC
October 2016
1 Read