1,346 results match your criteria Brain Stimulation [Journal]


Inter-ictal assay of peripheral circulating inflammatory mediators in migraine patients under adjunctive cervical non-invasive vagus nerve stimulation (nVNS): A proof-of-concept study.

Brain Stimul 2019 Jan 19. Epub 2019 Jan 19.

University Hospital Bonn, Rheinische Friedrich-Wilhelms-University of Bonn, Germany; Department of Psychiatry, Germany; Division of Medical Psychology, Germany. Electronic address:

Objective: To assay peripheral inter-ictal cytokine serum levels and possible relations with non-invasive vagus nerve stimulation (nVNS) responsiveness in migraineurs.

Methods: This double-blinded, sham-controlled study enrolled 48 subjects and measured headache severity, frequency [headache days/month, number of total and mild/moderate/severe classified attacks/month], functional state [sleep, mood, body weight, migraine-associated disability] and serum levels of inflammatory markers [inter-ictal] using enzyme-linked immunoassays at baseline and after 2 months of adjunctive nVNS compared to sham stimulation and suitably matched controls.

Results: No significant differences were observed at baseline and after 2 months for headache severity, total attacks/month, headache days/month and functional outcome [sleep, mood, disability] between verum and sham nVNS. Read More

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http://dx.doi.org/10.1016/j.brs.2019.01.008DOI Listing
January 2019

No evidence for modulation of outer hair-cell function by 4-Hz transcranial alternating current stimulation.

Brain Stimul 2019 Feb 1. Epub 2019 Feb 1.

Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Oxfordlaan 55, 6229 EV, Maastricht, the Netherlands.

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http://dx.doi.org/10.1016/j.brs.2019.01.022DOI Listing
February 2019

Light at the end of the tunnel: Improvement of post-stroke visual field defect after open-label navigated perilesional rTMS.

Brain Stimul 2019 Jan 31. Epub 2019 Jan 31.

Ain Shams Neuromodulation Research Lab, Neurology dep, Faculty of Medicine, Ain Shams University, Cairo, Egypt. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2019.01.018DOI Listing
January 2019

Autonomic arousal elicited by subcallosal cingulate stimulation is explained by white matter connectivity.

Brain Stimul 2019 Jan 26. Epub 2019 Jan 26.

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 101 Woodruff Circle, Atlanta, 30322, GA, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 1470 Madison Ave, New York, 10029, NY, USA.

Background: Subcallosal cingulate deep brain stimulation (SCC DBS) is an experimental treatment for severe depression. Surgery is performed with awake patients and intraoperative stimulation produces acute behavioral responses in select contacts. While there have been reports on the relationship between acute intraoperative behaviors and their relation to the location of the contacts, there are no descriptions of the physiological changes that accompany them. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X193004
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http://dx.doi.org/10.1016/j.brs.2019.01.015DOI Listing
January 2019
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Lowering the seizure threshold in electroconvulsive therapy using transcranial magnetic stimulation: A case report.

Brain Stimul 2019 Jan 24. Epub 2019 Jan 24.

Department of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czechia.

We demonstrate the feasibility of lowering the seizure threshold using a combined approach of electroconvulsive therapy and transcranial magnetic stimulation. High-frequency transcranial magnetic stimulation of the supplementary motor area shortly before each electroconvulsive treatment session resulted in a reduction of the seizure threshold by half in a male patient with a severe psychotic depressive episode of bipolar affective disorder. Read More

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http://dx.doi.org/10.1016/j.brs.2019.01.012DOI Listing
January 2019

Direction of TDCS current flow in human sensorimotor cortex influences behavioural learning.

Brain Stimul 2019 Jan 28. Epub 2019 Jan 28.

Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, London, UK.

Background: Recent studies have shown that neurophysiological outcomes of transcranial direct current stimulation (TDCS) are influenced by current flow in brain regions between the electrodes, and in particular the orientation of current flow relative to the cortical surface.

Objective: We asked whether the directional effects of TDCS on physiological measures in the motor system would also be observed on motor behaviours.

Methods: We applied TDCS during the practice of a ballistic movement task to test whether it affected learning or the retention of learning 48 h later. Read More

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http://dx.doi.org/10.1016/j.brs.2019.01.016DOI Listing
January 2019

Successful continued TMS treatment after a seizure: A letter to the editor.

Authors:
Debra J Stultz

Brain Stimul 2019 Jan 19. Epub 2019 Jan 19.

Sultz Sleep & Behavioral Health, 6171 Childers Road, Barboursville, WV, 25504, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2019.01.009DOI Listing
January 2019

Medial septal stimulation increases seizure threshold and improves cognition in epileptic rats.

Brain Stimul 2019 Jan 17. Epub 2019 Jan 17.

Department of Neurological Surgery, University of California, Davis, USA; Center for Neuroscience, University of California, Davis, USA. Electronic address:

Background: Temporal lobe epilepsy is most prevalent among focal epilepsies, and nearly one-third of patients are refractory to pharmacological intervention. Persistent cognitive and neurobehavioral comorbidities also occur due to the recurrent nature of seizures and medication-related side effects.

Hypothesis: Electrical neuromodulation is an effective strategy to reduce seizures both in animal models and clinically, but its efficacy to modulate cognition remains unclear. Read More

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http://dx.doi.org/10.1016/j.brs.2019.01.005DOI Listing
January 2019

Transcutaneous spinal direct current stimulation improves locomotor learning in healthy humans.

Brain Stimul 2019 Jan 29. Epub 2019 Jan 29.

Human Cortical Physiology and Neurorehabilitation Section, NINDS, USA.

Background: Ambulation is an essential aspect of daily living and is often impaired after brain and spinal cord injuries. Despite the implementation of standard neurorehabilitative care, locomotor recovery is often incomplete.

Objective: In this randomized, sham-controlled, double-blind, parallel design study, we aimed to determine if anodal transcutaneous spinal direct current stimulation (anodal tsDCS) could improve training effects on locomotion compared to sham (sham tsDCS) in healthy subjects. Read More

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http://dx.doi.org/10.1016/j.brs.2019.01.017DOI Listing
January 2019

Dual-site high-density 4Hz transcranial alternating current stimulation applied over auditory and motor cortical speech areas does not influence auditory-motor mapping.

Brain Stimul 2019 Jan 18. Epub 2019 Jan 18.

Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, 6229 EV, Maastricht, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X193003
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http://dx.doi.org/10.1016/j.brs.2019.01.007DOI Listing
January 2019
3 Reads

Case report of the treatment of diabetic foot disease using spinal cord stimulation.

Authors:
Jing-Bo Gao Min Bao

Brain Stimul 2019 Jan 28. Epub 2019 Jan 28.

Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, China. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2019.01.014DOI Listing
January 2019

A single case report of a patient with stuttering who improved after open label TMS.

Brain Stimul 2019 Jan 19. Epub 2019 Jan 19.

Service of Clinical Neurophysiology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

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http://dx.doi.org/10.1016/j.brs.2019.01.011DOI Listing
January 2019

Probing short-latency cortical inhibition in the visual cortex with transcranial magnetic stimulation: A reliability study.

Brain Stimul 2019 Jan 20. Epub 2019 Jan 20.

School of Kinesiology, University of Michigan, 401 Washtenaw Ave, 41809, Ann Arbor, MI, USA. Electronic address:

Background: Transcranial magnetic stimulation (TMS) is a non-invasive method to stimulate localized brain regions. Despite widespread use in motor cortex, TMS is seldom performed in sensory areas due to variable, qualitative metrics.

Objective: Assess the reliability and validity of tracing phosphenes, and to investigate the stimulation parameters necessary to elicit decreased visual cortex excitability with paired-pulse TMS at short inter-stimulus intervals. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X193004
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http://dx.doi.org/10.1016/j.brs.2019.01.013DOI Listing
January 2019
4 Reads

Time courses of BOLD responses during transcranial near-infrared laser irradiation.

Brain Stimul 2019 Jan 16. Epub 2019 Jan 16.

Division of Bioinformation and Therapeutic Systems, National Defense Medical College Research Institute, Tokorozawa, Saitama, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2019.01.006DOI Listing
January 2019

Personalized striatal targets for deep brain stimulation in obsessive-compulsive disorder.

Brain Stimul 2018 Dec 20. Epub 2018 Dec 20.

Laboratory for Clinical Neuroscience, Centre for Biomedical Technology, Universidad Politecnica de Madrid, Spain; Department of Neuroimaging, Reina Sofia Centre for Alzheimer's Disease, Madrid, Spain.

Background: Psychiatric conditions currently treated with deep brain stimulation (DBS), such as obsessive-compulsive disorder (OCD), are heterogeneous diseases with different symptomatic dimensions, indicating that fixed neuroanatomical DBS targets for all OCD cases may not be efficacious.

Objective/hypothesis: We tested whether the optimal DBS target for OCD is fixed for all patients or whether it is individualized and related to each patient's symptomatic content. Further, we explored if the optimal target can be predicted by combining functional neuroimaging and structural connectivity. Read More

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http://dx.doi.org/10.1016/j.brs.2018.12.226DOI Listing
December 2018
1 Read

Intermittent theta burst stimulation for major depression during pregnancy.

Brain Stimul 2019 Jan 12. Epub 2019 Jan 12.

Department of Psychiatry, University of Toronto, Canada; Temerty Centre for Therapeutic Brain Intervention and Campbell Family Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X193003
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http://dx.doi.org/10.1016/j.brs.2019.01.003DOI Listing
January 2019
3 Reads

Publication trends in transcranial magnetic stimulation: a 30-year panorama.

Brain Stimul 2019 Jan 9. Epub 2019 Jan 9.

Division of Functional and Restorative Neurosurgery, Department of Neurosurgery, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. Electronic address:

Background: Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulatory technique that has broad diagnostic and therapeutic potential across a range of neurological and psychiatric diseases.

Objective: This study utilises a bibliometric approach to systematically and comprehensively evaluate the literature on TMS from the last three decades.

Methods: The Scopus citation database was used to identify all peer-reviewed journal articles concerning TMS over the period 1988-2017. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X193003
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http://dx.doi.org/10.1016/j.brs.2019.01.002DOI Listing
January 2019
4 Reads

Differential effects of bifrontal tDCS on arousal and sleep duration in insomnia patients and healthy controls.

Brain Stimul 2019 Jan 4. Epub 2019 Jan 4.

Department of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany; University Hospital of Psychiatry and Psychotherapy, Bern, Switzerland. Electronic address:

Background: Arousal and sleep represent basic domains of behavior, and alterations are of high clinical importance.

Objective/hypothesis: The aim of this study was to further elucidate the neurobiology of insomnia disorder (ID) and the potential for new treatment developments, based on the modulation of cortical activity through the non-invasive brain stimulation technique transcranial direct current stimulation (tDCS). Specifically, we tested the hypotheses that bi-frontal anodal tDCS shortens and cathodal tDCS prolongs total sleep time in patients with ID, compared to sham stimulation. Read More

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http://dx.doi.org/10.1016/j.brs.2019.01.001DOI Listing
January 2019
2 Reads

Sham tDCS: A hidden source of variability? Reflections for further blinded, controlled trials.

Brain Stimul 2019 Jan 2. Epub 2019 Jan 2.

INSERM U1028, CNRS UMR5292, Lyon Neuroscience Research Center, Psychiatric Disorders: from Resistance to Response Team, F-69000, France; University Lyon 1, Villeurbanne, F-69000, France; Centre Hospitalier Le Vinatier, Lyon, F-69000, France. Electronic address:

Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique increasingly used to modulate neural activity in the living brain. In order to establish the neurophysiological, cognitive or clinical effects of tDCS, most studies compare the effects of active tDCS to those observed with a sham tDCS intervention. In most cases, sham tDCS consists in delivering an active stimulation for a few seconds to mimic the sensations observed with active tDCS and keep participants blind to the intervention. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X183139
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http://dx.doi.org/10.1016/j.brs.2018.12.977DOI Listing
January 2019
8 Reads

The effect of electroconvulsive therapy on cerebral monoamine oxidase A expression in treatment-resistant depression investigated using positron emission tomography.

Brain Stimul 2019 Jan 2. Epub 2019 Jan 2.

Neuroimaging Labs (NIL) PET, MRI, EEG, TMS and Chemical Lab, Department of Psychiatry and Psychotherapy, Medical University of Vienna, Austria. Electronic address:

Background: Electroconvulsive therapy (ECT) constitutes one of the most effective antidepressant treatment strategies in major depression (MDD). Despite its common use and uncontested efficacy, its mechanism of action is still insufficiently understood. Previously, we showed that ECT is accompanied by a global decrease of serotonin-1A receptors in MDD; however, further studies to investigate the involvement of the serotonergic system in the mechanism of action of ECT are warranted. Read More

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http://dx.doi.org/10.1016/j.brs.2018.12.976DOI Listing
January 2019
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Effect of transcranial direct current stimulation on exercise performance: A systematic review and meta-analysis.

Brain Stimul 2018 Dec 24. Epub 2018 Dec 24.

Graduate Program in Physical Education, State University of Londrina, Londrina, PR, Brazil; Center of Mathematics, Computation, and Cognition, Universidade Federal do ABC, São Bernardo do Campo, SP, Brazil. Electronic address:

Background: Transcranial direct current stimulation (tDCS) has been used to improve exercise performance, though the protocols used, and results found are mixed.

Objective: We aimed to analyze the effect of tDCS on improving exercise performance.

Methods: A systematic search was performed on the following databases, until December 2017: PubMed/MEDLINE, Embase, Web of Science, SCOPUS, and SportDiscus. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X183064
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http://dx.doi.org/10.1016/j.brs.2018.12.227DOI Listing
December 2018
6 Reads

Effects of single-session versus multi-session non-invasive brain stimulation on craving and consumption in individuals with drug addiction, eating disorders or obesity: A meta-analysis.

Brain Stimul 2018 Dec 27. Epub 2018 Dec 27.

School of Humanities, Tongji University, Shanghai, 200092, China; School of Psychological and Cognitive Sciences, Peking University, Beijing, 100871, China; Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, 100871, China; PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing, 100871, China. Electronic address:

Background: Brain stimulation interventions are increasingly used to reduce craving and consumption in individuals with drug addiction or excessive eating behavior. However, the efficacy of these novel treatments and whether effect sizes are affected by the length of the intervention has not been comprehensively evaluated.

Objective: A meta-analytical approach was employed to evaluate the effectiveness of non-invasive excitatory brain stimulation [transcranial Direct Current Stimulation (tDCS) and high-frequency repetitive Transcranial Magnetic Stimulation (rTMS)] targeted at dorsolateral prefrontal cortex (dlPFC) for reducing craving and consumption levels in drug and eating addiction, including both single- and multi-session protocols. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X183139
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http://dx.doi.org/10.1016/j.brs.2018.12.975DOI Listing
December 2018
6 Reads

Hand perceptions induced by single pulse transcranial magnetic stimulation over the primary motor cortex.

Brain Stimul 2018 Dec 23. Epub 2018 Dec 23.

Center for Neuroprosthetics, School of Life Science, Swiss Federal Institute of Technology (Ecole Polytechnique Fédérale de Lausanne), Campus Biotech, Geneva, Switzerland; Laboratory of Cognitive Neuroscience, Brain Mind Institute, School of Life Science, Swiss Federal Institute of Technology (Ecole Polytechnique Fédérale de Lausanne), Campus Biotech, Geneva, Switzerland; Center for Neuroprosthetics, School of Life Science, Swiss Federal Institute of Technology (Ecole Polytechnique Fédérale de Lausanne), Campus SUVA, Sion, Switzerland. Electronic address:

Background: When single pulse transcranial magnetic stimulation (TMS) is applied over the primary motor cortex (M1) with sufficient intensity, it evokes muscular contractions (motor-evoked potentials, MEPs) and muscle twitches (TMS-evoked movements). Participants may also report various hand sensations related to TMS, but the perception elicited by TMS and its relationship to MEPs and evoked movements has not been systematically studied.

Objective: The main aim of this work is to evaluate participants' kinesthetic and somatosensory hand perceptions elicited by single-pulse TMS over M1-hand area at different intensities of stimulation and their relation with MEPs and TMS-evoked movements. Read More

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http://dx.doi.org/10.1016/j.brs.2018.12.972DOI Listing
December 2018
3 Reads

Repetitive anodal transcranial direct current stimulation improves neurological outcome and survival in a ventricular fibrillation cardiac arrest rat model.

Brain Stimul 2018 Dec 27. Epub 2018 Dec 27.

School of Biomedical Engineering and Imaging Medicine, Army Medical University, Chongqing, China. Electronic address:

Background: Transcranial direct current stimulation (tDCS) modulates neuronal activity and is a potential therapeutic tool for many neurological diseases. However, its beneficial effects on post cardiac arrest syndrome remains uncertain.

Objective/hypothesis: We investigated the effects of repetitive anodal tDCS on neurological outcome and survival in a ventricular fibrillation (VF) cardiac arrest rat model. Read More

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http://dx.doi.org/10.1016/j.brs.2018.12.974DOI Listing
December 2018
2 Reads

Delusions following deep brain stimulation of the nucleus accumbens.

Brain Stimul 2018 Dec 26. Epub 2018 Dec 26.

Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Neuroscience, Amsterdam, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X183139
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http://dx.doi.org/10.1016/j.brs.2018.12.973DOI Listing
December 2018
4 Reads

Beneficial effects of cerebellar rTMS stimulation on a patient with spinocerebellar ataxia type 6.

Brain Stimul 2018 Dec 16. Epub 2018 Dec 16.

Department of Neurology, Shenzhen People's Hospital, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China; Department of Neurology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, Guangdong, China. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2018.12.225DOI Listing
December 2018
1 Read

The neuromodulatory and hormonal effects of transcutaneous vagus nerve stimulation as evidenced by salivary alpha amylase, salivary cortisol, pupil diameter, and the P3 event-related potential.

Brain Stimul 2018 Dec 14. Epub 2018 Dec 14.

Institute of Psychology, Leiden University, Leiden, 2333, AK, Netherlands; Leiden Institute for Brain and Cognition, Leiden University, Leiden, 2300, RC, Netherlands.

Background: Transcutaneous vagus nerve stimulation (tVNS) is a new, non-invasive technique being investigated as an intervention for a variety of clinical disorders, including epilepsy and depression. It is thought to exert its therapeutic effect by increasing central norepinephrine (NE) activity, but the evidence supporting this notion is limited.

Objective: In order to test for an impact of tVNS on psychophysiological and hormonal indices of noradrenergic function, we applied tVNS in concert with assessment of salivary alpha amylase (SAA) and cortisol, pupil size, and electroencephalograph (EEG) recordings. Read More

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http://dx.doi.org/10.1016/j.brs.2018.12.224DOI Listing
December 2018
1 Read

Anodal transcranial direct current stimulation over the right dorsolateral prefrontal cortex enhances reflective judgment and decision-making.

Brain Stimul 2018 Dec 7. Epub 2018 Dec 7.

School of Psychology, College of Applied Health and Communities, University of East London, London, United Kingdom; Centre for Affective Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

Background: Accounts of cognitive processes in judgment and decision-making are frequently based on a dual-process framework, which reflects two qualitatively different types of processing: intuitive (Type 1) and analytical (Type 2) processes.

Objective: The present study investigated the effects of bilateral transcranial direct current stimulation (tDCS) to the dorsolateral prefrontal cortex (DLPFC) on judgment and decision-making performance.

Methods: Participants received anodal tDCS stimulation to the right DLPFC, left DLPFC or sham. Read More

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http://dx.doi.org/10.1016/j.brs.2018.12.003DOI Listing
December 2018
2 Reads

Repetitive transcranial magnetic stimulation in cluster headache.

Brain Stimul 2019 Mar - Apr;12(2):383-384. Epub 2018 Dec 13.

Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, 226014, India.

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http://dx.doi.org/10.1016/j.brs.2018.12.004DOI Listing
December 2018
2 Reads

rTMS can improve post-stroke apraxia of speech. A case study.

Brain Stimul 2019 Mar - Apr;12(2):380-382. Epub 2018 Dec 10.

Istituto Auxologico Italiano, IRCCS, Department of Neurorehabilitation Sciences, Ospedale San Luca, Milano, Italy; Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2018.12.006DOI Listing
December 2018
1 Read

The effects of transcranial direct current stimulation on objective and subjective indexes of exercise performance: A systematic review and meta-analysis.

Brain Stimul 2019 Mar - Apr;12(2):242-250. Epub 2018 Dec 8.

Mind, Brain and Behavior Research Centre, Department of Experimental Psychology, University of Granada, Spain.

Objective: To examine the effects of transcranial direct current stimulation (tDCS) on objective and subjective indexes of exercise performance.

Design: Systematic review and meta-analysis.

Data Sources: A systematic literature search of electronic databases (PubMed, Web of Science, Scopus, Google Scholar) and reference lists of included articles up to June 2018. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X183042
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http://dx.doi.org/10.1016/j.brs.2018.12.002DOI Listing
December 2018
8 Reads

Electroconvulsive therapy induced gray matter increase is not necessarily correlated with clinical data in depressed patients.

Brain Stimul 2019 Mar - Apr;12(2):335-343. Epub 2018 Dec 4.

Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany.

Background: Electroconvulsive therapy (ECT) and depression have been associated with brain volume changes, especially in the hippocampus and the amygdala.

Methods: In this retrospective study we collected data from individual pre-post ECT whole brain magnetic resonance imaging scans of depressed patients from six German university hospitals. Gray matter volume (GMV) changes were quantified via voxel-based morphometry in a total sample of 92 patients with major depressive episodes (MDE). Read More

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http://dx.doi.org/10.1016/j.brs.2018.11.017DOI Listing
December 2018
1 Read

Response to "A comment on postural stability improvement in older adults with high fall risk after anodal tDCS on primary motor cortex versus cerebellar stimulation".

Brain Stimul 2019 Mar - Apr;12(2):369-370. Epub 2018 Dec 6.

Discipline of Physiotherapy, Department of Rehabilitation, Nutrition and Sport, School of Allied Health, La Trobe University, Bundoora, Victoria, 3086, Australia.

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http://dx.doi.org/10.1016/j.brs.2018.12.005DOI Listing
December 2018
1 Read

Motor training modulates intracortical inhibitory dynamics in motor cortex during movement preparation.

Brain Stimul 2019 Mar - Apr;12(2):300-308. Epub 2018 Nov 9.

Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, University College London (UCL), London, WC1N 3BG, UK; Oxford Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB), Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK; Oxford Centre for Human Brain Mapping (OHBA), Department of Psychiatry, University of Oxford, Oxford, OX3 7JX, UK. Electronic address:

Background: The primary motor cortex (M1) has a vital role to play in the learning of novel motor skills. However, the physiological changes underpinning this learning, particularly in terms of dynamic changes during movement preparation, are incompletely understood. In particular, a substantial decrease in resting gamma-amino butyric acid (GABA) activity, i. Read More

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http://dx.doi.org/10.1016/j.brs.2018.11.002DOI Listing
November 2018
1 Read

Catecholaminergic modulation of indices of cognitive flexibility: A pharmaco-tDCS study.

Brain Stimul 2019 Mar - Apr;12(2):290-295. Epub 2018 Dec 7.

Department of Psychology, Sociology and Politics, Sheffield Hallam University, Sheffield, UK. Electronic address:

Background: Dopaminergic activity within the dorsolateral prefrontal cortex (dlPFC) has been implicated in the control of cognitive flexibility. Much of the evidence for a causative relationship between cognitive flexibility and dopamine has come from animal studies, whilst human data have largely been correlational.

Objective/hypothesis: The current study examines whether changes in dopamine levels through tyrosine administration and suppression of dlPFC activity via cathodal tDCS could be causally related to cognitive flexibility as measured by task switching and reversal learning. Read More

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http://dx.doi.org/10.1016/j.brs.2018.12.001DOI Listing
December 2018
1 Read

False positives associated with responder/non-responder analyses based on motor evoked potentials.

Brain Stimul 2019 Mar - Apr;12(2):314-318. Epub 2018 Dec 3.

Acquired Brain Injury Rehabilitation Alliance, School of Health Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK. Electronic address:

Background: A trend in the non-invasive brain stimulation literature is to assess the outcome of an intervention using a responder analysis whereby participants are di- or trichotomised in order that they may be classified as either responders or non-responders.

Objective: Examine the extent of the Type I error in motor evoked potential (MEP) data subjected to responder analyses.

Methods: Seven sets of 30 MEPs were recorded from the first dorsal interosseous muscle in 52 healthy volunteers. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X183041
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http://dx.doi.org/10.1016/j.brs.2018.11.015DOI Listing
December 2018
4 Reads

Individual white matter bundle trajectories are associated with deep brain stimulation response in obsessive-compulsive disorder.

Brain Stimul 2019 Mar - Apr;12(2):353-360. Epub 2018 Nov 27.

Amsterdam UMC, University of Amsterdam, Department of Psychiatry, Amsterdam Neuroscience, Meibergdreef 9, 1105, AZ, Amsterdam, the Netherlands.

Background: The ventral anterior limb of the internal capsule (vALIC) is a target for deep brain stimulation (DBS) in obsessive-compulsive disorder (OCD). Conventional surgical planning is based on anatomical landmarks.

Objective/hypothesis: We hypothesized that treatment response depends on the location of the active DBS contacts with respect to individual white matter bundle trajectories. Read More

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http://dx.doi.org/10.1016/j.brs.2018.11.014DOI Listing
November 2018
2 Reads

Electroconvulsive therapy for anti-N-methyl-d-aspartate (NMDA) receptor encephalitis: A systematic review of cases.

Brain Stimul 2019 Mar - Apr;12(2):329-334. Epub 2018 Dec 4.

Metro South Addiction and Mental Health, Brisbane, Australia; University of Queensland, Brisbane, Australia.

Background: Anti-NMDA receptor encephalitis most commonly presents with psychiatric symptoms such as behavioural disturbance, catatonia and psychosis. Although the primary treatment is with immunomodulatory therapy, psychiatric symptoms often require adjuvant management. Side effects and treatment resistance limits the use of psychotropics, but the role of ECT has been minimally reviewed. Read More

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http://dx.doi.org/10.1016/j.brs.2018.11.016DOI Listing
December 2018
2 Reads

The effect of transcutaneous auricular vagus nerve stimulation on treatment-resistant depression monitored by resting-state fMRI and MRS: The first case report.

Brain Stimul 2019 Mar - Apr;12(2):377-379. Epub 2018 Nov 27.

Department of Radiology, Guang' anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2018.11.013DOI Listing
November 2018
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Miniature ultrasound ring array transducers for transcranial ultrasound neuromodulation of freely-moving small animals.

Brain Stimul 2019 Mar - Apr;12(2):251-255. Epub 2018 Nov 17.

School of Electrical Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea. Electronic address:

Background: Current transcranial ultrasound stimulation for small animal in vivo experiment is limited to acute stimulation under anesthesia in stereotaxic fixation due to bulky and heavy curved transducers.

Methods: We developed a miniaturized ultrasound ring array transducer which is capable of invoking motor responses through neuromodulation of freely-moving awake mice.

Results: The developed transducer is a 32-element, 183-kHz ring array with a weight of 0. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X183037
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http://dx.doi.org/10.1016/j.brs.2018.11.007DOI Listing
November 2018
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A systematic review and meta-analysis of the effects of transcranial direct current stimulation (tDCS) on episodic memory.

Brain Stimul 2019 Mar - Apr;12(2):231-241. Epub 2018 Nov 17.

Department of Psychology, Kingston University, Penrhyn Road, Kingston Upon Thames, KT1 2EE, United Kingdom.

Background: In the past decade, several studies have examined the effects of transcranial direct current stimulation (tDCS) on long-term episodic memory formation and retrieval. These studies yielded conflicting results, likely due to differences in stimulation parameters, experimental design and outcome measures.

Objectives: In this work we aimed to assess the robustness of tDCS effects on long-term episodic memory using a meta-analytical approach. Read More

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http://dx.doi.org/10.1016/j.brs.2018.11.008DOI Listing
November 2018
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A comment on postural stability improvement in older adults with high fall risk after anodal tDCS on primary motor cortex versus cerebellar stimulation.

Brain Stimul 2019 Mar - Apr;12(2):367-368. Epub 2018 Nov 23.

Motor Behavior Laboratory, University of Florida, Gainesville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2018.11.011DOI Listing
November 2018
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Stability of the cardiovascular response during single-pulse TMS in perinatal stroke.

Brain Stimul 2019 Mar - Apr;12(2):371-373. Epub 2018 Nov 20.

Division of Rehabilitation Science, Medical School, University of Minnesota, Minneapolis, MN, USA; Division of Physical Therapy, Medical School, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1016/j.brs.2018.11.010DOI Listing
November 2018
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Inferior thalamic peduncle deep brain stimulation for treatment-refractory obsessive-compulsive disorder: A phase 1 pilot trial.

Brain Stimul 2019 Mar - Apr;12(2):344-352. Epub 2018 Nov 27.

Division of Neurosurgery, University of Toronto, Canada. Electronic address:

Background: Several different surgical procedures targeting the limbic circuit have been utilized for severe, treatment resistant obsessive-compulsive disorder; however, there has only been limited exploration of the inferior thalamic peduncle (ITP). The aim of this study was to determine the safety and initial efficacy of ITP deep brain stimulation (DBS) in patients with severe obsessive-compulsive disorder.

Methods: Patients with severe, treatment-refractory obsessive-compulsive disorder were enrolled into this open-label phase 1 DBS pilot study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X183041
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http://dx.doi.org/10.1016/j.brs.2018.11.012DOI Listing
November 2018
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TMS motor mapping: Comparing the absolute reliability of digital reconstruction methods to the golden standard.

Brain Stimul 2019 Mar - Apr;12(2):309-313. Epub 2018 Nov 10.

Department of Rehabilitation Medicine, Erasmus MC, Rotterdam, the Netherlands; Rijndam Rehabilitation Center, Rotterdam, the Netherlands; Department of Plastic and Reconstructive Surgery, Erasmus MC, Rotterdam, the Netherlands.

Background: Changes in transcranial magnetic stimulation motor map parameters can be used to quantify plasticity in the human motor cortex. The golden standard uses a counting analysis of motor evoked potentials (MEPs) acquired with a predefined grid. Recently, digital reconstruction methods have been proposed, allowing MEPs to be acquired with a faster pseudorandom procedure. Read More

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http://dx.doi.org/10.1016/j.brs.2018.11.005DOI Listing
November 2018
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Temperature increases by kilohertz frequency spinal cord stimulation.

Brain Stimul 2019 Jan - Feb;12(1):62-72. Epub 2018 Oct 17.

Department of Biomedical Engineering, The City College of New York, New York, NY, 10031, USA. Electronic address:

Introduction: Kilohertz frequency spinal cord stimulation (kHz-SCS) deposits significantly more power in tissue compared to SCS at conventional frequencies, reflecting increased duty cycle (pulse compression). We hypothesize kHz-SCS increases local tissue temperature by joule heat, which may influence the clinical outcomes.

Methods: To establish the role of tissue heating in KHZ-SCS, a decisive first step is to characterize the range of temperature changes expected during conventional and KHZ-SCS protocols. Read More

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http://dx.doi.org/10.1016/j.brs.2018.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301103PMC
October 2018
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ECT-induced brain plasticity correlates with positive symptom improvement in schizophrenia by voxel-based morphometry analysis of grey matter.

Brain Stimul 2019 Mar - Apr;12(2):319-328. Epub 2018 Nov 17.

Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200030, China; CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Chinese Academy of Science, China; Brain Science and Technology Research Center, Shanghai Jiaotong University, Shanghai, 200030, China; Bio-X Institute, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiaotong University, Shanghai, 200030, China. Electronic address:

Background: Electroconvulsive therapy (ECT) is often considered as an augmentation of antipsychotic treatment for schizophrenia in drug-refractory cases. However, the mechanisms underlying the observed therapeutic effects are still not understood.

Objective: We aimed to investigate changes in whole brain grey matter volume (GMV) before and after modified ECT. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X183037
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http://dx.doi.org/10.1016/j.brs.2018.11.006DOI Listing
November 2018
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Relation between the electric field and activation of cortical neurons in transcranial electrical stimulation.

Brain Stimul 2019 Mar - Apr;12(2):275-289. Epub 2018 Nov 10.

School of Electrical Engineering and Computer Science, Gwangju Institute of Science & Technology, South Korea. Electronic address:

Background: To address the brain areas and circuits affected by transcranial electrical stimulation (tES), which had been used widely to treat psychiatric and neurological diseases, the stimulus-induced electric field in the cortex was calculated using a head model that reflects anatomical information. To obtain detailed information at the macroscopic and microscopic levels, multi-scale modeling was proposed that integrates the head model with multi-compartmental models of cortical neurons.

Objective: Our goal was to use multi-scale modeling to describe the relation between the stimulus-induced electric field and neuronal responses during tES. Read More

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http://dx.doi.org/10.1016/j.brs.2018.11.004DOI Listing
November 2018
10 Reads