Repeated olanzapine treatment mitigates PTSD like symptoms in rats with changes in cell signaling factors.
Brain Res Bull 2018 Jun 11. Epub 2018 Jun 11.
Neurotherapeutics Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (B enhance the sensitizaanaras Hindu University), Varanasi, U.P., 221 005, India. Electronic address:
Post Traumatic Stress Disorder is an anxiety disorder with prolonged distortion of rational behavior. In this study, we report the preclinical potential of olanzapine (OLZ) in the treatment of PTSD. Since the atypical antipsychotics have modulating effects on cell protective and destructive factors, we tested the effects of OLZ in PTSD regarding these cell modulating factors. Read More