326 results match your criteria Brain MRI Appearance of Hemorrhage


MR Imaging for Assessing Injury Severity and Prognosis in Acute Traumatic Spinal Cord Injury.

Radiol Clin North Am 2019 Mar 17;57(2):319-339. Epub 2018 Nov 17.

Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, Room M779, San Francisco, CA 94143, USA; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA.

T2-weighted (T2W) imaging is the most important sequence for detection of acute traumatic spinal cord pathology in clinical practice. Intramedullary hemorrhage on T2W imaging is associated with some component of irreversible injury and arguably the most robust MR imaging predictor of injury severity. The MR imaging appearance of the injured spinal cord in the early stages of injury is highly dynamic, and the time delay from injury to imaging must be considered in image interpretation. Read More

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http://dx.doi.org/10.1016/j.rcl.2018.09.004DOI Listing

MRI Presentation of Infectious Intracranial Aneurysms in Infective Endocarditis.

Neurocrit Care 2018 Dec 5. Epub 2018 Dec 5.

Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.

Background: The radiographic appearance of infectious intracranial aneurysms (IIAs) of infective endocarditis (IE) on magnetic resonance imaging (MRI) of brain is varied. We aimed to describe the IIA-specific MRI features in a series of patients with IIAs.

Methods: Records of patients with active IE who had digital subtraction angiography (DSA) at a tertiary medical center from January 2011 to December 2016 were reviewed. Read More

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http://link.springer.com/10.1007/s12028-018-0654-1
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http://dx.doi.org/10.1007/s12028-018-0654-1DOI Listing
December 2018
10 Reads

Correlation of clinical parameters with imaging findings to confirm the diagnosis of fat embolism syndrome.

Int J Burns Trauma 2018 20;8(5):135-144. Epub 2018 Oct 20.

Department of Radiology, Hamad Medical Corporation Doha, Qatar.

Background: Fat embolism syndrome (FES) is a multi-organ dysfunction caused by the fat emboli. The diagnostic of FES remains a challenge for clinicians. The clinical criteria including those of Gurd's and Wilson's although universally used for its diagnosis are not specific. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261919PMC
October 2018
1 Read

Post-operative complications of craniotomy and craniectomy.

Emerg Radiol 2019 Feb 25;26(1):99-107. Epub 2018 Sep 25.

Department of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, PO Box 648, Rochester, NY, 14642, USA.

Craniotomy and craniectomy are widely performed emergent neurosurgical procedures and are the prescribed treatment for a variety of conditions from trauma to cancer. It is vital for the emergency radiologist to be aware of expected neuroimaging findings in post-craniotomy and craniectomy patients in order to avoid false positives. It is just as necessary to be familiar with postsurgical complications in these patients to avoid delay in lifesaving treatment. Read More

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http://link.springer.com/10.1007/s10140-018-1647-2
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http://dx.doi.org/10.1007/s10140-018-1647-2DOI Listing
February 2019
26 Reads

Pitfalls in the Imaging Interpretation of Intracranial Hemorrhage.

Authors:
Humberto Morales

Semin Ultrasound CT MR 2018 Oct 3;39(5):457-468. Epub 2018 Aug 3.

Section of Neuroradiology, University of Cincinnati Medical Center, 234 Goodman St, Cincinnati, OH, 45267-0761. Electronic address:

Intracranial hemorrhage (ICH) is one of the most common pathologic findings in the emergent computed tomography (CT) imaging. ICH presents as hyperattenuation in parenchymal, subarachnoid, subdural, or epidural location. However, the initial interpretation of areas of hyperattenuation can be challenging as other pathologic or nonpathologic processes (eg, calcifications, vascular malformations, highly cellular tumors, iodinated contrast, or beam-hardening artifacts) can have similar appearance. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08872171183006
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http://dx.doi.org/10.1053/j.sult.2018.07.001DOI Listing
October 2018
9 Reads

Intracranial Hemorrhage Imaging.

Semin Ultrasound CT MR 2018 Oct 27;39(5):441-456. Epub 2018 Feb 27.

Department of Radiology, Stanford University School of Medicine, Stanford, CA.

Intracranial hemorrhage is a medical event frequently encountered in the clinical practice of radiology that has significant potential for patient morbidity and mortality. The expedient and accurate identification of intracranial hemorrhage as well as elucidation of the underlying cause can assist in optimizing the care of these patients. In this review, we attempt to familiarize the reader with the imaging appearance of multiple types of intracranial hemorrhage, both intra-axial and extra-axial and utilizing both computed tomography and magnetic resonance imaging, as well as to provide a framework for assessment of the underlying cause of the hemorrhage. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08872171183000
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http://dx.doi.org/10.1053/j.sult.2018.01.003DOI Listing
October 2018
10 Reads

Atypical chronological changes on neuroimaging in the epidermoid in the frontal lobe with intracystic hemorrhage and tumor growth: Case report.

Radiol Case Rep 2018 Dec 13;13(6):1133-1136. Epub 2018 Sep 13.

Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tenodai, Tsukuba, Ibaraki, 305-8575 Japan.

Intracranial epidermoids are rare lesions accounting for 0.2%-1.8% of all intracranial tumors. Read More

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http://dx.doi.org/10.1016/j.radcr.2018.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138860PMC
December 2018
1 Read

One-year prognosis of non-traumatic cortical subarachnoid haemorrhage: A prospective series of 34 patients.

Neurologia 2018 Jun 11. Epub 2018 Jun 11.

Servicio de Neurología, Hospital La Fe, Valencia, España.

Introduction: Cortical subarachnoid haemorrhage (cSAH) has multiple aetiologies. No prospective study has reported the long-term progression of the condition. The objective of this study is to describe the clinical and aetiological characteristics of patients with cSAH and to gain insight into prognosis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02134853183002
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http://dx.doi.org/10.1016/j.nrl.2017.12.008DOI Listing
June 2018
25 Reads

[SPONTANEOUS PARENCHYMAL INTRACRANIAL HEMORRHAGE - A DIAGNOSTIC CHALLENGE].

Harefuah 2018 03;157(3):158-161

Department of Neurology, Hadassah Medical Center, Jerusalem Israel.

Introduction: Non-traumatic intracranial hemorrhage (ICH) is a devastating event associated with a high rate of morbidity and mortality. Patient age, hemorrhage location, number of foci, and underlying diseases are important clues to the etiology. Non-contrast head CT, given its availability and high sensitivity in detecting blood products, is frequently the first tool to readily detect ICH; however, different types of hemorrhages may share a common appearance on CT and the optimal therapeutic approach varies depending on etiology. Read More

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March 2018
8 Reads

Cerebral Microbleeds: Imaging and Clinical Significance.

Radiology 2018 Apr;287(1):11-28

From the Affidea Centre de Diagnostic Radiologique de Carouge (CDRC), Geneva, Switzerland (S.H.); Faculty of Medicine, University of Geneva, Geneva, Switzerland (S.H.); Department of Surgical Sciences, Radiology, Uppsala University, Uppsala, Sweden (S.H., E.M.L.); Department of Neuroradiology, University Hospital Freiburg, Freiburg, Germany (S.H.); Department of Radiology and Nuclear Medicine and Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands (M.W.V.); Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, the Netherlands (J.P.A.K., F.B.); Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, Institute of Neurology, University College London, London, England (H.R.J., F.B.).

Cerebral microbleeds (CMBs), also referred to as microhemorrhages, appear on magnetic resonance (MR) images as hypointense foci notably at T2*-weighted or susceptibility-weighted (SW) imaging. CMBs are detected with increasing frequency because of the more widespread use of high magnetic field strength and of newer dedicated MR imaging techniques such as three-dimensional gradient-echo T2*-weighted and SW imaging. The imaging appearance of CMBs is mainly because of changes in local magnetic susceptibility and reflects the pathologic iron accumulation, most often in perivascular macrophages, because of vasculopathy. Read More

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http://dx.doi.org/10.1148/radiol.2018170803DOI Listing
April 2018
4 Reads

Evaluation of lymphatic vessel dilatations by anterior segment swept-source optical coherence tomography: case report.

BMC Ophthalmol 2017 Oct 23;17(1):194. Epub 2017 Oct 23.

Faculty of Medicine Department of Ophthalmology, Semmelweis University, Budapest, Hungary.

Background: Conjunctival lymphangiectasia is a rare condition presumably caused by the obstruction of lymphatic channels or by an abnormal connection between conjunctival lymphatic and blood vessels. Diagnosis is based on clinical appearance and histology. We report a case of conjunctival lymphangiectasia in which anterior segment optical coherence tomography (OCT) was used to assist the diagnosis and the planning of the biopsy location. Read More

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http://dx.doi.org/10.1186/s12886-017-0588-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654095PMC
October 2017
14 Reads

Initial Investigation into Microbleeds and White Matter Signal Changes following Radiotherapy for Low-Grade and Benign Brain Tumors Using Ultra-High-Field MRI Techniques.

AJNR Am J Neuroradiol 2017 Dec 28;38(12):2251-2256. Epub 2017 Sep 28.

From the Departments of Medical Biophysics (J.-G.B., G.S.B., R.S.M.)

Background And Purpose: External beam radiation therapy is a common treatment for many brain neoplasms. While external beam radiation therapy adheres to dose limits to protect the uninvolved brain, areas of high dose to normal tissue still occur. Patients treated with chemoradiotherapy can have adverse effects such as microbleeds and radiation necrosis, but few studies exist of patients treated without chemotherapy. Read More

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http://dx.doi.org/10.3174/ajnr.A5395DOI Listing
December 2017
3 Reads

Status Epilepticus Secondary to Pseudonodular Hemorragic Occipital Lesion with Edema: "Non Semper Ea Sunt, Quae Videntur, Decipit Frons Prima Multos" (Things Are Not Always What They Seem; The First Appearance Deceives Many).

World Neurosurg 2017 Aug 27;104:1044.e1-1044.e3. Epub 2017 May 27.

Department of Neurosurgery, Institute for Scientific and Care Research, Main Hospital of Santa Maria Nuova, Reggio Emilia, Italy; Neurosurgery-Neurotraumatology Unit, University Hospital of Parma, Parma, Italy.

We report a case in which common radiologic images masked a rare case of supratentorial hemangioblastoma (HBL). Other peculiarities of this case are the clinical presentation with status epilepticus and the occurrence of a supratentorial HBL unrelated to von Hippel-Lindau syndrome. Based on clinical and radiologic findings, including massive cerebral edema and hemorrhagic presentation, our preoperative diagnosis was a cerebral metastasis. Read More

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http://dx.doi.org/10.1016/j.wneu.2017.05.114DOI Listing
August 2017
13 Reads

Characterization of a novel murine model for spontaneous hemorrhagic stroke using in vivo PET and MR multiparametric imaging.

Neuroimage 2017 07 1;155:245-256. Epub 2017 May 1.

Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tuebingen, Tuebingen, Germany. Electronic address:

The clinical use of Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) has proven to be a strong diagnostic tool in the field of neurology. The reliability of these methods to confirm clinical diagnoses has guided preclinical research to utilize these techniques for the characterization of animal disease models. Previously, we demonstrated that an endothelial cell-specific ablation of the murine Serum Response Factor (Srf) results in blood brain barrier (BBB) breakdown and hemorrhagic stroke. Read More

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http://dx.doi.org/10.1016/j.neuroimage.2017.04.071DOI Listing
July 2017
25 Reads

Early appearance of tuberous sclerosis complex on cerebral ultrasound in extremely preterm infant.

J Neonatal Perinatal Med 2017 ;10(2):203-206

Department of Paediatrics, Section Neonatology, Amalia Children Hospital, Radboud University Medical Centre Nijmegen, Nijmegen, The Netherlands.

Tuberous sclerosis complex (TSC) is an inherited neurocutaneous disorder. Diagnosis of early onset TSC in newborn infants is usually made by cardiac ultrasound because of circulatory problems due to cardiac rhabdomyoma. Early appearance of cortical tubers on cerebral ultrasound in newborn infants is very rare. Read More

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http://dx.doi.org/10.3233/NPM-171652DOI Listing
May 2018
15 Reads

[A clinical analysis of 5 patients with infratentorial primary angiitis of central nervous system].

Zhonghua Nei Ke Za Zhi 2017 Apr;56(4):284-289

Department of Neurology, Navy General Hospital, Beijing 100048, China.

To explore the clinical characteristics of infratentorial primary angiitis in central nervous system(PACNS). A total of 5 cases diagnosed as infratentorial PACNS in the neurology department of Navy General Hospital of PLA in 2015 were enrolled in the study. The clinical, imaging and pathological data were collected and analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0578-1426.2017.04.009DOI Listing
April 2017
4 Reads

Cytotoxic Lesions of the Corpus Callosum That Show Restricted Diffusion: Mechanisms, Causes, and Manifestations.

Radiographics 2017 Mar-Apr;37(2):562-576. Epub 2017 Feb 6.

From the Department of Radiology, St Luke's International Hospital, 9-1 Akashicho, Chuo, Tokyo 104-8560, Japan (J.S., N.K., Y.N.); and the Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, Iowa (T.M.).

Cytotoxic lesions of the corpus callosum (CLOCCs) are secondary lesions associated with various entities. CLOCCs have been found in association with drug therapy, malignancy, infection, subarachnoid hemorrhage, metabolic disorders, trauma, and other entities. In all of these conditions, cell-cytokine interactions lead to markedly increased levels of cytokines and extracellular glutamate. Read More

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http://dx.doi.org/10.1148/rg.2017160085DOI Listing
October 2017
36 Reads

Evolution of cerebral microbleeds after cranial irradiation in medulloblastoma patients.

Neurology 2017 Feb 25;88(8):789-796. Epub 2017 Jan 25.

From The Hemorrhagic Stroke Research Program (D.R., A.C., L.X., A.V., S.M.-R., A.V.), J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Department of Medicine (D.R.), Faculty of Medicine, Naresuan University, Phitsanulok, Thailand; Image Sciences Institute (H.J.K.), University Medical Center Utrecht, the Netherlands; Department of Radiation Oncology (H.A.S.), Massachusetts General Hospital, Boston; and Department of Neurology (C.M.G., J.D.), Division of Neuro-Oncology, Massachusetts General Hospital Cancer Center, and Center for Regenerative Medicine, Harvard Medical School, Boston.

Objective: To characterize the temporal and spatial pattern of cerebral microbleeds (CMBs) after cranial irradiation in patients with medulloblastoma.

Methods: We retrospectively identified patients with medulloblastoma treated with craniospinal irradiation at the Massachusetts General Hospital between 1999 and 2015. Longitudinal MRI including T2*-weighted gradient-recalled echo (GRE) sequences were reviewed, and the prevalence, spatial pattern, and risk factors associated with CMBs were characterized. Read More

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http://dx.doi.org/10.1212/WNL.0000000000003631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344076PMC
February 2017
9 Reads
1 Citation
8.290 Impact Factor

Mantle Cell Lymphoma with Central Nervous System Involvement Simulating Bilateral Subdural Hematomas.

World Neurosurg 2017 Mar 4;99:808.e1-808.e2. Epub 2017 Jan 4.

Department of Pathology, Hospital General Universitario de Castellón, Castellón, Spain.

We describe a 71-year-old-patient receiving antiplatelet therapy and being attended by emergency medical services for psychomotor retardation and gait disturbance. An emergency computed tomographic scan showed a bilateral subacute hematoma. The patient reported a fall 2 weeks earlier. Read More

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http://dx.doi.org/10.1016/j.wneu.2016.12.122DOI Listing
March 2017
2 Reads

Goggle-like Appearance of Injured Cerebellothalamic Axons Surrounding Red Nuclei in Holmes Tremor.

Can J Neurol Sci 2017 Jul 15;44(4):429-431. Epub 2016 Dec 15.

4Department of Neurology,University of Minnesota,Minneapolis,Minnesota.

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http://dx.doi.org/10.1017/cjn.2016.418DOI Listing
July 2017
11 Reads
1.600 Impact Factor

Dual-Energy CT in Emergency Neuroimaging: Added Value and Novel Applications.

Radiographics 2016 Nov-Dec;36(7):2186-2198

From the Department of Radiology, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115.

Dual-energy computed tomography (CT) is a powerful diagnostic tool that is becoming more widely clinically available. Dual-energy CT has the potential to aid in the detection or add diagnostic confidence in the evaluation of a variety of emergent neurologic conditions with use of postprocessing techniques that allow one to take advantage of the different x-ray energy-dependent absorption behaviors of different materials. Differentiating iodine from hemorrhage may help in delineating CT angiographic spot signs, which are small foci of intracranial hemorrhage seen on CT angiograms in cases of acute hemorrhage. Read More

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http://dx.doi.org/10.1148/rg.2016160069DOI Listing
September 2017
7 Reads

Magnetic Resonance Imaging Characteristics of Hyperacute Intracerebral Hemorrhage.

J Vasc Interv Neurol 2016 Oct;9(2):10-13

Department of Neurology, University of Tennessee Health Sciences Center, Memphis, TN, USA.

Background: Magnetic resonance imaging (MRI) of the brain is highly sensitive for detecting intracerebral hemorrhage (ICH). Understanding of the imaging characteristics of hyperacute ICH is limited secondary to availability and increased time to scan relative to other imaging modalities.

Objective: In this report, we present the MRI characteristics of two patients who developed ICH while on the MRI table. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094255PMC
October 2016
4 Reads

Magnetic Resonance Imaging Appearance and Mechanism of Action of Five Hemostatic Agents Used in Neurosurgery.

Vet Surg 2016 Nov 23;45(8):996-1004. Epub 2016 Sep 23.

Department of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado.

Objective: To describe the magnetic resonance (MR) image appearance of 5 hemostatic agents placed in the brain, and to review their clinical application.

Study Design: Descriptive ex vivo and in vivo study.

Animals: Canine cadavers (n=4), client-owned dogs (n=4). Read More

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http://dx.doi.org/10.1111/vsu.12551DOI Listing
November 2016
13 Reads

Evolution of Subarachnoid Hemorrhage Extension in Lobar Hemorrhage in the Early Chronic Phase and the Impact on Cerebral Amyloid Angiopathy Criteria.

J Stroke Cerebrovasc Dis 2016 Oct 16;25(10):2502-5. Epub 2016 Aug 16.

Department of Neurology, Hôpital Caremeau, CHU Nîmes, Nîmes Cedex 4, France; Institut de Génomique Fonctionnelle, UMR5203, Université Montpellier, Montpellier, France.

Background: Subarachnoid hemorrhage extension (SAHE) in acute lobar hemorrhage (LH) is frequent. Little is known about the short- and medium-term radiological evolution of SAHE. Our aim was to study this evolution by magnetic resonance imaging (MRI). Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.06.026DOI Listing
October 2016
4 Reads

Clinical characteristics and risk factors of Intracranial hemorrhage in patients following allogeneic hematopoietic stem cell transplantation.

Ann Hematol 2016 Oct 3;95(10):1637-43. Epub 2016 Aug 3.

Peking University People's Hospital, Institute of Hematology, Beijing Key Laboratory of HSCT, No. 11, Xizhimen South Street, Xicheng District, Beijing, 100044, China.

Intracranial hemorrhage (ICH) is one of the most life-threatening neurological complications after allogeneic hematopoietic stem cell transplantation. Although cerebral complications and its causes after allo-HSCT are well documented, assessment of the incidence and risk factors of intracranial hemorrhage following allo-HSCT are less discussed. A nested case-control study was conducted involving 160 subjects drawn from 2169 subjects who underwent HSCT at Peking University People's Hospital between 2004 and 2014. Read More

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http://dx.doi.org/10.1007/s00277-016-2767-yDOI Listing
October 2016
29 Reads
1 Citation
2.634 Impact Factor

Ischemic pituitary adenoma apoplexy-Clinical appearance and prognosis after surgical intervention.

Clin Neurol Neurosurg 2016 Sep 7;148:142-6. Epub 2016 Jul 7.

Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, Japan.

Background: Several retrospective investigations have recommended more passive surgical indications for intratumoral hemorrhage of pituitary adenomas due to probable spontaneous resolution. However, no definitive analyses have compared pituitary adenomas with hemorrhagic apoplexy and intratumoral hemorrhage without evident apoplectic symptoms or pituitary adenoma infarction.

Methods: This study retrospectively identified 43 patients with symptomatic pituitary apoplexy among 1067 patients with pituitary adenomas initially treated by surgery at a single institute between April 2005 and May 2015, with 27 cases of hemorrhagic (2. Read More

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http://dx.doi.org/10.1016/j.clineuro.2016.07.013DOI Listing
September 2016
42 Reads

Cerebral cavernous malformations with diffuse manifestation: A benign entity?

J Neurol Sci 2016 Aug 15;367:335-41. Epub 2016 Jun 15.

Department of Neurological Surgery, Juntendo University Urayasu Hospital, Urayasu, Chiba, Japan.

Purpose: Cerebral cavernous malformations (CCMs) are a distinct cerebrovascular disease. A fraction of CCMs present as diffuse manifestations distributed over the cerebral hemispheres, cerebellum, and brainstem. The purpose of the present study was to explore the clinical picture of such CCMs. Read More

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http://dx.doi.org/10.1016/j.jns.2016.06.012DOI Listing
August 2016
7 Reads

Combined 3 Tesla MRI Biomarkers Improve the Differentiation between Benign vs Malignant Single Ring Enhancing Brain Masses.

PLoS One 2016 13;11(7):e0159047. Epub 2016 Jul 13.

Department of Neurosciences, Imaging and Clinical Sciences, University "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy.

Purpose: To evaluate whether the combination of imaging biomarkers obtained by means of different 3 Tesla (3T) Magnetic Resonance Imaging (MRI) advanced techniques can improve the diagnostic accuracy in the differentiation between benign and malignant single ring-enhancing brain masses.

Materials And Methods: 14 patients presenting at conventional 3T MRI single brain mass with similar appearance as regard ring enhancement, presence of peri-lesional edema and absence of hemorrhage signs were included in the study. All lesions were histologically proven: 5 pyogenic abscesses, 6 glioblastomas, and 3 metastases. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159047PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943588PMC
July 2017
7 Reads

Application value of magnetic resonance imaging in diagnosing central nervous system lymphoma.

Pak J Med Sci 2016 Mar-Apr;32(2):389-93

Mingming Zhang, Department of Radiology, Binzhou People's Hospital, Binzhou, Shandong, 256610, China.

Objective: To describe the magnetic resonance imaging (MRI) appearance of central nervous system lymphoma.

Methods: We retrospectively reviewed MRI images of 40 patients who had pathologically proven primary central nervous system lymphoma (PCNSL) and received treatment in Binzhou People's Hospital, Shandong, China from January to December in 2014. Location, size and form of tumor was observed and relevant data were recorded for analysis. Read More

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http://dx.doi.org/10.12669/pjms.322.9013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859029PMC

Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study.

Lancet Neurol 2016 07 11;15(8):811-819. Epub 2016 May 11.

Hemorrhagic Stroke Research Group, Massachusetts General Hospital, Boston, MA, USA.

Background: Loss of cortical grey matter is a diagnostic marker of many neurodegenerative diseases, and is a key mediator of cognitive impairment. We postulated that cerebral amyloid angiopathy (CAA), characterised by cortical vascular amyloid deposits, is associated with cortical tissue loss independent of parenchymal Alzheimer's disease pathology. We tested this hypothesis in patients with hereditary cerebral haemorrhage with amyloidosis-Dutch type (HCHWA-D), a monogenetic disease with minimal or no concomitant Alzheimer's disease pathology, as well as in patients with sporadic CAA and healthy and Alzheimer's disease controls. Read More

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http://dx.doi.org/10.1016/S1474-4422(16)30030-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248657PMC
July 2016
26 Reads

Clinical Deterioration and Early Imaging Changes after Intravenous Tissue Plasminogen Activator Administration in Acute Ischemic Stroke Patients.

J Stroke Cerebrovasc Dis 2016 Jul 25;25(7):1823-1827. Epub 2016 Apr 25.

Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, Ohio.

Background And Purpose: Clinical worsening is a known complication following acute ischemic stroke. This study attempted to determine the mechanism of deterioration by correlating clinical findings with changes on computed tomography or magnetic resonance.

Methods: From a single university medical center, 30 consecutive acute ischemic stroke patients who received intravenous tissue plasminogen activator within 3 hours of symptom onset during a 3-year period were identified from a quality database that included all hospitalized patients either admitted with strokes or with in-hospital strokes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10523057160015
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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.03.016DOI Listing
July 2016
3 Reads

MRI Appearance of Intracerebral Iodinated Contrast Agents: Is It Possible to Distinguish Extravasated Contrast Agent from Hemorrhage?

AJNR Am J Neuroradiol 2016 08 31;37(8):1418-21. Epub 2016 Mar 31.

From the Departments of Neuroradiology (O.N., S.D., M.W.).

Background And Purpose: Hyperattenuated cerebral areas on postinterventional CT are a common finding after endovascular stroke treatment. There is uncertainty about the extent to which these hyperattenuated areas correspond to hemorrhage or contrast agent that extravasated into infarcted parenchyma during angiography. We evaluated whether it is possible to distinguish contrast extravasation from blood on MR imaging. Read More

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http://www.ajnr.org/cgi/doi/10.3174/ajnr.A4755
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http://dx.doi.org/10.3174/ajnr.A4755DOI Listing
August 2016
56 Reads

Limitations of T2*-Gradient Recalled-Echo and Susceptibility-Weighted Imaging in Characterizing Chronic Subdural Hemorrhage in Infant Survivors of Abusive Head Trauma.

AJNR Am J Neuroradiol 2016 09 31;37(9):1752-6. Epub 2016 Mar 31.

Department of Radiology (G.L.H.), Primary Children's Hospital, Salt Lake City, Utah.

A possible misconception among radiologists is that chronic subdural hemorrhage should show some degree of blooming on T2*-gradient recalled-echo or susceptibility-weighted sequences such as SWI and susceptibility-weighted angiography, which is not necessarily true. We present 5 cases of chronic subdural hemorrhages in infants, demonstrating intensity near or greater than that of CSF with variable amounts of hemosiderin staining along the neomembranes. We review the physiology and MR imaging physics behind the appearance of a chronic subdural hemorrhage, highlighting that the absence of a BBB can allow hemosiderin to be completely removed from the subdural compartment. Read More

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http://dx.doi.org/10.3174/ajnr.A4769DOI Listing
September 2016
2 Reads

Microbleeds may expand acutely after traumatic brain injury.

Neurosci Lett 2016 Mar 18;617:207-12. Epub 2016 Feb 18.

Department of Neurosurgery, Pécs Medical School, H-7623, Rét. u. 2., Pécs, Hungary; MTA-PTE Clinical Neuroscience MR Research Group, Hungary. Electronic address:

Background And Purpose: Susceptibility weighted imaging (SWI) is a very sensitive tool for the detection of microbleeds in traumatic brain injury (TBI). The number and extent of such traumatic microbleeds (TMBs) have been shown to correlate with the severity of the injury and the clinical outcome. However, the acute dynamics of TMBs have not been revealed so far. Read More

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http://dx.doi.org/10.1016/j.neulet.2016.02.028DOI Listing
March 2016
12 Reads

Treatment of hemorrhagic acute disseminated encephalomyelitis with cyclophosphamide.

Am J Health Syst Pharm 2016 Feb;73(4):202-5

UC San Diego Health System, San Diego, CA.

Purpose: Improvements in hemorrhagic and clinical symptoms in a patient with hemorrhagic acute disseminated encephalomyelitis (ADEM) treated with i.v. cyclophosphamide are reported. Read More

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http://dx.doi.org/10.2146/ajhp150079DOI Listing
February 2016
1 Read

Hemorrhagic Cerebellar Abscess.

World Neurosurg 2016 Apr 25;88:692.e17-22. Epub 2015 Dec 25.

Division of Neurosurgery, Departments of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

Background: Brain abscess represents a significant medical problem, accounting for 1 in every 10,000 U.S. hospital admissions and imposing a mortality of 17%-32%. Read More

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http://dx.doi.org/10.1016/j.wneu.2015.12.039DOI Listing
April 2016
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New Cerebral Microbleeds After Mechanical Thrombectomy for Large-Vessel Occlusion Strokes.

Medicine (Baltimore) 2015 Nov;94(47):e2180

From the Department of Neurosurgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China (Z-SS); Division of Interventional Neuroradiology (GRD, RJ, ST, NRG, VS, FV), Department of Neurology (JLS, DK, LKA, SS, DSL), Department of Emergency Medicine (SS), Department of Neurosurgery (NRG, PMV), Division of Diagnostic Neuroradiology (NS, JPV), and Neurovascular Imaging Research Core (DSL), David Geffen School of Medicine at UCLA, Los Angeles, CA; Department of Radiology, Kaiser Permanente Medical Center, Los Angeles, CA (LF); Interventional Neuroradiology and Neurocritical Care Services, Madigan Army Medical Center, Tacoma, WA (YL), Guangdong Province Key Laboratory of Brain Function and Disease, Sun Yat-sen University, Guangzhou, China (Z-SS).

The interval appearance of cerebral microbleeds (CMBs) after endovascular treatment has never been described. We investigated the frequency and predictors of new CMBs that developed shortly after mechanical thrombectomy for acute ischemic stroke, and its impact on clinical outcome.We retrospectively analyzed patients with large-vessel occlusion strokes treated with Merci Retriever, Penumbra System, or stent-retriever devices. Read More

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http://dx.doi.org/10.1097/MD.0000000000002180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059022PMC
November 2015
32 Reads

Pathological Evaluation of Radiation-Induced Vascular Lesions of the Brain: Distinct from De Novo Cavernous Hemangioma.

Yonsei Med J 2015 Nov;56(6):1714-20

Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

Purpose: We aimed to evaluate the histologic and radiologic findings of vascular lesions after stereotactic radiosurgery (SRS) categorized as radiation-induced cavernous hemangioma (RICH).

Materials And Methods: Among 89 patients who underwent neurosurgery for cavernous hemangioma, eight RICHs from 7 patients and 10 de novo CHs from 10 patients were selected for histopathological and radiological comparison.

Results: Histologically, RICHs showed hematoma-like gross appearance. Read More

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http://dx.doi.org/10.3349/ymj.2015.56.6.1714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630064PMC
November 2015
10 Reads

Infratentorial hemorrhagic cerebral proliferative angiopathy: A rare presentation of a rare disease.

Asian J Neurosurg 2015 Jul-Sep;10(3):240-2

Department of Neurosurgery, Sawai Man Singh Medical College, Jaipur, Rajasthan, India.

Cerebral proliferative angiopathy (CPA) is a unique and rare vascular malformation with distinct clinico-radiological features. CPA is associated with low risk of hemorrhage as compared to classical cerebral arteriovenous malformations (AVMs). Infratentorial location of diffuse nidus is also an uncommon presentation. Read More

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http://dx.doi.org/10.4103/1793-5482.161185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553743PMC
September 2015
9 Reads

Imaging Cerebral Microhemorrhages in Military Service Members with Chronic Traumatic Brain Injury.

Radiology 2016 Feb 15;278(2):536-45. Epub 2015 Sep 15.

From the National Intrepid Center of Excellence (NICoE), Walter Reed National Military Medical Center, 4860 S Palmer Rd, Bethesda, MD 20889-5649 (W.L., K.S., J.S.S., D.J., P.H.Y., J.O., E.B.S., T.R.O., G.R.); Center for Neuroscience and Regenerative Medicine, Bethesda, Md (D.J., T.R.O., G.R.); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Md (D.J.); Biomedical Engineering Department, Cornell University, New York, NY (T.L., Y.W.); and The NorthTide Group, Sterling, Va (W.L., E.B.S.).

Purpose: To detect cerebral microhemorrhages in military service members with chronic traumatic brain injury by using susceptibility-weighted magnetic resonance (MR) imaging. The longitudinal evolution of microhemorrhages was monitored in a subset of patients by using quantitative susceptibility mapping.

Materials And Methods: The study was approved by the Walter Reed National Military Medical Center institutional review board and is compliant with HIPAA guidelines. Read More

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http://dx.doi.org/10.1148/radiol.2015150160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571643PMC
February 2016
4 Reads

Clinical evolutional aspects of chronic subdural haematomas - literature review.

J Med Life 2015 ;8 Spec Issue:26-33

Department of Neurosurgery, University Hospital Bucharest, Romania.

Apparently trivial, one of the most frequent pathologies in neurosurgical practice, chronic subdural haematoma, continues to be a challenge for the neurosurgeons both from the therapeutic and postoperatory complications point of view, taking into account that it is frequently met in elders, who usually present a complex pathology. The fact that, by definition, there is a latent period between the moment the brain injury, usually minor, occurs and the appearance of clinical symptomatology, frequently makes the trauma be ignored, this complicating the diagnosis and most of the times delaying the application of the adequate treatment. Developing slowly in time, in weeks or months, the aspect that chronic subdural haematoma usually occurs in elders should not be neglected, its clinical symptomatology often debuting with memory and attention disorders, so that the patient is usually referred to psychiatrists or neurologists, only a paraclinical investigation (CT scan or MRI) being able to establish the diagnosis. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564043PMC

Role of intraoperative indocyanine green video-angiography to identify small, posterior fossa arteriovenous malformations mimicking cavernous angiomas. Technical report and review of the literature on common features of these cerebral vascular malformations.

Clin Neurol Neurosurg 2015 Nov 26;138:45-51. Epub 2015 Jul 26.

Institute of Neurosurgery, Catholic University of Rome, Italy.

Objective: To illustrate the usefulness of intraoperative indocyanine green videoangiography (ICG-VA) to identify the nidus and feeders of a small cerebellar AVM resembling a cavernous hemangioma. To review the unique features regarding the overlay between these two vascular malformations and to highlight the importance to identify with ICG-VA, and treat accordingly, the arterial and venous vessels of the AVM.

Methods: A 36-year old man presented with bilateral cerebellar hemorrhage. Read More

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http://dx.doi.org/10.1016/j.clineuro.2015.07.016DOI Listing
November 2015
18 Reads

Prospective Hemorrhage Rates of Cerebral Cavernous Malformations in Children and Adolescents Based on MRI Appearance.

AJNR Am J Neuroradiol 2015 Nov 13;36(11):2177-83. Epub 2015 Aug 13.

From the Department of Neuroradiology (O.N., M.W.), University Hospital Aachen, Aachen, Germany

Background And Purpose: Current classifications of cerebral cavernous malformations focus solely on morphologic aspects. Our aim was to provide a morphologic classification that reflects hemorrhage rates.

Materials And Methods: We retrospectively categorized 355 cavernous malformations of 70 children and adolescents according to their morphologic appearance on MR imaging and calculated prospective hemorrhage rates on the basis of survival functions for 255 lesions in 25 patients with a radiologic observation period of >180 days. Read More

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http://www.ajnr.org/content/early/2015/08/13/ajnr.A4427.full
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http://www.ajnr.org/cgi/doi/10.3174/ajnr.A4427
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http://dx.doi.org/10.3174/ajnr.A4427DOI Listing
November 2015

The effects of anti-angiogenic therapy on the formation of radiation-induced microbleeds in normal brain tissue of patients with glioma.

Neuro Oncol 2016 Jan 22;18(1):87-95. Epub 2015 Jul 22.

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California (J.M.L., E.E.-B., S.C., S.J.N.); Department of Neurosurgery, University of California San Francisco, San Francisco, California (A.M.M., N.B., S.M.C., S.C.); Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California (A.M.M.); Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California (S.J.N.).

Background: Radiotherapy (RT) is an integral component in managing patients with glioma, but the damage it may cause to healthy brain tissue and quality of life is of concern. Susceptibility-weighted imaging (SWI) is highly sensitive to the detection of microbleeds that occur years after RT. This study's goals were to characterize the evolution of radiation-induced microbleeds in normal-appearing brain and determine whether the administration of an anti-angiogenic agent altered this process. Read More

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http://dx.doi.org/10.1093/neuonc/nov128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677411PMC
January 2016
11 Reads

Medullary hemorrhage that preceded the onset of multiple cavernous angiomas.

Intern Med 2015 1;54(7):843-6. Epub 2015 Apr 1.

Division of Neurology, Department of Internal Medicine, Shin-Oyama City Hospital, Japan.

Medullary hemorrhage is rare, and the causative role of hypertension still remains controversial. Cavernous angioma and other vascular malformations have been reported to cause medullary hemorrhage. A 53-year-old man was admitted to our hospital for vertigo. Read More

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http://dx.doi.org/10.2169/internalmedicine.54.3657DOI Listing
September 2015
13 Reads

Fetal MRI: An approach to practice: A review.

Authors:
Sahar N Saleem

J Adv Res 2014 Sep 11;5(5):507-23. Epub 2013 Jun 11.

Department of Radiology, Kasr Al Ainy Faculty of Medicine, Cairo University, Cairo, Egypt.

MRI has been increasingly used for detailed visualization of the fetus in utero as well as pregnancy structures. Yet, the familiarity of radiologists and clinicians with fetal MRI is still limited. This article provides a practical approach to fetal MR imaging. Read More

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http://dx.doi.org/10.1016/j.jare.2013.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294280PMC
September 2014
2 Reads
7 Citations

The neurological outcomes of cerebellar injury in premature infants.

Brain Dev 2015 Oct 13;37(9):858-63. Epub 2015 Feb 13.

Department of Pediatric Neurology, Takuto Rehabilitation Center for Children, Sendai, Japan; Department of Pediatrics, Tohoku University School of Medicine, Sendai, Japan.

Aim: Cerebellar injury is a characteristic injury associated with preterm infants. However, the impact of cerebellar injury on the development of preterm infants is unclear.

Method: We reviewed magnetic resonance image studies of preterm infants with cerebral palsy retrospectively and evaluated the developmental outcomes. Read More

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http://dx.doi.org/10.1016/j.braindev.2015.01.009DOI Listing
October 2015
9 Reads

Giant cavernous malformations in young adults: report of two cases, radiological findings and surgical consequences.

JBR-BTR 2014 Sep-Oct;97(5):274-8

Department of Pathology, University Hospital and University of Antwerp, Belgium.

Cerebral cavernous malformations, also known as cavernous angioma or cavernoma, are a type of vascular disorder. They consist of abnormally large vascular cavities or sinusoid channels of varying size. The majority of cavernous malformations in the brain are small and do not always present with symptoms. Read More

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February 2015
2 Reads

Subdural porous and notched mini-grid electrodes for wireless intracranial electroencephalographic recordings.

J Multidiscip Healthc 2014 9;7:573-86. Epub 2014 Dec 9.

Neurology Service, Department of Medicine, Notre-Dame Hospital, Centre Hospitalier de l'Université de Montréal (CHUM), QC, Canada.

Background: Intracranial electroencephalography (EEG) studies are widely used in the presurgical evaluation of drug-refractory patients with partial epilepsy. Because chronic implantation of intracranial electrodes carries a risk of infection, hemorrhage, and edema, it is best to limit the number of electrodes used without compromising the ability to localize the epileptogenic zone (EZ). There is always a risk that an intracranial study may fail to identify the EZ because of suboptimal coverage. Read More

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http://dx.doi.org/10.2147/JMDH.S64269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266360PMC
December 2014
42 Reads