345 results match your criteria Brain MRI Appearance of Hemorrhage


Onscreen-guided resection of extra-axial and intra-axial forebrain masses through registration of a variable-suction tissue resection device with a neuronavigation system.

Vet Surg 2020 May 27;49(4):676-684. Epub 2020 Mar 27.

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado.

Objectives: To describe a novel surgical technique in which neuronavigation is used to guide a tissue resection device during excision of forebrain masses in locations difficult to visualize optically.

Study Design: Short case series.

Animals: Six dogs and one cat with forebrain masses (five neoplastic, two nonneoplastic) undergoing excision with a novel tissue resection device and veterinary neuronavigation system. Read More

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http://dx.doi.org/10.1111/vsu.13414DOI Listing

Distinguishing mimics from true hemorrhagic cavernous malformations.

J Clin Neurosci 2020 Apr 22;74:11-17. Epub 2020 Jan 22.

Departments of Neurology, Mayo Clinic, Rochester, MN, USA. Electronic address:

Cavernous malformations (CM) are angiographically occult vascular malformations. CM appear as discrete, small lesions with mixed-signal characteristics on T2 reflecting the underlying pathology. However, the appearance is not pathognomonic. Read More

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http://dx.doi.org/10.1016/j.jocn.2020.01.070DOI Listing

Traumatic microbleeds suggest vascular injury and predict disability in traumatic brain injury.

Brain 2019 11;142(11):3550-3564

Center for Neuroscience and Regenerative Medicine, Bethesda, Maryland, USA.

Traumatic microbleeds are small foci of hypointensity seen on T2*-weighted MRI in patients following head trauma that have previously been considered a marker of axonal injury. The linear appearance and location of some traumatic microbleeds suggests a vascular origin. The aims of this study were to: (i) identify and characterize traumatic microbleeds in patients with acute traumatic brain injury; (ii) determine whether appearance of traumatic microbleeds predict clinical outcome; and (iii) describe the pathology underlying traumatic microbleeds in an index patient. Read More

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http://dx.doi.org/10.1093/brain/awz290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821371PMC
November 2019
1 Read

Pseudohypoxic Brain Swelling: Report of 2 Cases and Introduction of the Lentiform Rim Sign as Potential MRI Marker.

World Neurosurg 2020 Jan 10;133:221-226. Epub 2019 Oct 10.

Department of Radiology and Interventional Neuroradiology, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: A rare but important complication related to otherwise uneventful brain and spine surgery is becoming more recognized and more frequently reported in the medical literature. This has been variably labeled as pseudohypoxic brain swelling or postoperative hypotension-associated venous congestion. This poorly understood condition occurs in the setting of surgical intervention and is thought to be related to cerebrospinal fluid leak or evacuation, decreased intracranial pressure, and subsequent development of deep venous congestion affecting the basal ganglia, thalami, and cerebellum. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.10.018DOI Listing
January 2020
1 Read

Small vessel disease in patients with subarachnoid hemorrhage: Prevalence and associations with vasospasm occurrence, severity and clinical outcomes.

Neuroradiol J 2019 Dec 30;32(6):438-444. Epub 2019 Sep 30.

Service d'Imagerie Morphologique et Fonctionnelle, Centre Hospitalier Sainte-Anne, Paris, France.

Purpose: Investigating the associations between cerebral small vessel disease (cSVD) burden and cerebral vasospasm (CVS), delayed cerebral ischemia (DCI) and clinical outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH).

Methods: Consecutive aSAH patients with initial (<7 days after onset) and 3-month follow-up brain magnetic resonance imaging (MRI) and clinical evaluation at 6 months were included. The cSVD burden score was built using MRI criteria. Read More

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http://dx.doi.org/10.1177/1971400919877470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856992PMC
December 2019
2 Reads

Tumoral Mimics of Subdural Hematomas: Case Report and Review of Diagnostic and Management Strategies in Primary B-Cell Lymphoma of the Subdural Space.

World Neurosurg 2020 Jan 25;133:49-54. Epub 2019 Sep 25.

Department of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Background: Subdural lymphomas are a rare subtype of primary central nervous system lymphomas that can radiographically mimic epidural blood and pose a diagnostic challenge. They can complicate treatment if not preemptively identified.

Methods: We present a case report of a subdural lymphoma that mimicked a compressive subdural hematoma, and we review the PubMed database for similar cases. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.09.091DOI Listing
January 2020
4 Reads

[A Case of Meningitis Caused by Globicatella sanguinis in a Patient with a Lumbo-peritoneal Shunt].

Mikrobiyol Bul 2019 Jul;53(3):343-347

Sivas Cumhuriyet University Faculty of Medicine, Department of Neurosurgery, Sivas, Turkey.

Globicatella sanguinis is catalase-negative, alpha-hemolytic, nonmotile, facultative anaerobic grampositive cocci, identified as a new species in 1992. Since the colony morphology in blood agar and microscopic appearance resembles streptococci, it is thought that some of the isolates previously identified in the Streptococcus viridans group were G.sanguinis species. Read More

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http://dx.doi.org/10.5578/mb.68131DOI Listing
July 2019
3 Reads

Contribution of acute infarcts to cerebral small vessel disease progression.

Ann Neurol 2019 10 12;86(4):582-592. Epub 2019 Aug 12.

Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.

Objective: To determine the contribution of acute infarcts, evidenced by diffusion-weighted imaging positive (DWI+) lesions, to progression of white matter hyperintensities (WMH) and other cerebral small vessel disease (SVD) markers.

Methods: We performed monthly 3T magnetic resonance imaging (MRI) for 10 consecutive months in 54 elderly individuals with SVD. MRI included high-resolution multishell DWI, and 3-dimensional fluid-attenuated inversion recovery, T1, and susceptibility-weighted imaging. Read More

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http://dx.doi.org/10.1002/ana.25556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771732PMC
October 2019
3 Reads

[A Case of Glioblastoma that Appeared One Year after the Removal of Subcortical Hematoma].

No Shinkei Geka 2019 Jun;47(6):667-672

Department of Neurosurgery, Toki General Hospital.

Subcortical bleeding from brain tumors is not rare. In the majority of cases, tumors are revealed within a few months after bleeding. We herein report a relatively rare case of glioblastoma(GBM)that appeared one year after the removal of a subcortical hematoma. Read More

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http://dx.doi.org/10.11477/mf.1436204002DOI Listing
June 2019
11 Reads

Postobliteration Arteriovenous Malformation Mimicking Malignant Change 30 Years After X-Knife Treatment-Case Report and Review of Literature.

World Neurosurg 2019 Aug 10;128:169-173. Epub 2019 May 10.

Division of Neurosurgery, Department of Surgery, Chimei Medical Center, Tainan, Taiwan; Department of Biotechnology, Southern Taiwan University of Science and Technology, Tainan, Taiwan. Electronic address:

Background: Arteriovenous malformations (AVMs) are potentially dangerous vascular anomalies of the brain that can cause seizures or intracranial hemorrhage in patients if left untreated. Because full excision of these lesions is not always possible in deep or eloquent areas of the brain, radiosurgical advances have gone a long way in the control and treatment of AVMs. Postradiosurgery AVMs are followed closely via outpatient clinics with serial imaging every few months to assess AVM obliteration. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.04.263DOI Listing
August 2019
5 Reads

A case of functioning gonadotroph adenoma in a reproductive aged woman.

Endocr J 2019 Jul 19;66(7):653-656. Epub 2019 Apr 19.

Department of Obstetrics and Gynecology, The University of Tokyo Hospital, Tokyo 1138655, Japan.

A 34-year-old woman presented our hospital with complaint of irregular menstruation and abnormal uterine bleeding lasting for a month. After her second parturition at the age of 27, her menstrual cycle had been regular, but it suddenly became irregular at the age of 30. Transvaginal ultrasound revealed the presence of ovarian mass, and the patient underwent diagnostic laparoscopic surgery. Read More

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https://www.jstage.jst.go.jp/article/endocrj/advpub/0/advpub
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http://dx.doi.org/10.1507/endocrj.EJ19-0066DOI Listing
July 2019
21 Reads

Cortical Superficial Siderosis Evolution.

Stroke 2019 04;50(4):954-962

From the Hemorrhagic Stroke Research Program, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (A.C., G.B., L.X., M.P., D.R., A.A., K.M.S., J.R., M.E.G., A.V., S.M.G.).

Background and Purpose- We investigated cortical superficial siderosis (cSS) progression and its clinical relevance for incident lobar intracerebral hemorrhage (ICH) risk, in probable cerebral amyloid angiopathy presenting with neurological symptoms and without ICH at baseline. Methods- Consecutive patients meeting modified Boston criteria for probable cerebral amyloid angiopathy from a single-center cohort who underwent magnetic resonance imaging (MRI) at baseline and during follow-up were analyzed. cSS progression was assessed by comparison of the baseline and follow-up images. Read More

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http://dx.doi.org/10.1161/STROKEAHA.118.023368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433512PMC
April 2019
10 Reads
5.723 Impact Factor

MR Imaging for Assessing Injury Severity and Prognosis in Acute Traumatic Spinal Cord Injury.

Radiol Clin North Am 2019 Mar 17;57(2):319-339. Epub 2018 Nov 17.

Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, Room M779, San Francisco, CA 94143, USA; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA.

T2-weighted (T2W) imaging is the most important sequence for detection of acute traumatic spinal cord pathology in clinical practice. Intramedullary hemorrhage on T2W imaging is associated with some component of irreversible injury and arguably the most robust MR imaging predictor of injury severity. The MR imaging appearance of the injured spinal cord in the early stages of injury is highly dynamic, and the time delay from injury to imaging must be considered in image interpretation. Read More

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http://dx.doi.org/10.1016/j.rcl.2018.09.004DOI Listing
March 2019
5 Reads

Transsphenoidal Removal of Retroclival Chondroma with Pituitary Transposition Manifesting as Repeated Subarachnoid Hemorrhage: A Case Report.

J Neurol Surg A Cent Eur Neurosurg 2019 May 1;80(3):228-232. Epub 2019 Feb 1.

Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan.

Background:  Intracranial chondromas are extremely rare and represent only 0.2% of all intracranial primary neoplasms. The histologic appearance lacks nuclear atypism and mitoses, and it usually shows low growth potential, although these benign features do not necessarily imply a good prognosis. Read More

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http://dx.doi.org/10.1055/s-0038-1677452DOI Listing
May 2019
7 Reads

MRI Presentation of Infectious Intracranial Aneurysms in Infective Endocarditis.

Neurocrit Care 2019 06;30(3):658-665

Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.

Background: The radiographic appearance of infectious intracranial aneurysms (IIAs) of infective endocarditis (IE) on magnetic resonance imaging (MRI) of brain is varied. We aimed to describe the IIA-specific MRI features in a series of patients with IIAs.

Methods: Records of patients with active IE who had digital subtraction angiography (DSA) at a tertiary medical center from January 2011 to December 2016 were reviewed. Read More

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http://link.springer.com/10.1007/s12028-018-0654-1
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http://dx.doi.org/10.1007/s12028-018-0654-1DOI Listing
June 2019
37 Reads

Correlation of clinical parameters with imaging findings to confirm the diagnosis of fat embolism syndrome.

Int J Burns Trauma 2018 20;8(5):135-144. Epub 2018 Oct 20.

Department of Radiology, Hamad Medical Corporation Doha, Qatar.

Background: Fat embolism syndrome (FES) is a multi-organ dysfunction caused by the fat emboli. The diagnostic of FES remains a challenge for clinicians. The clinical criteria including those of Gurd's and Wilson's although universally used for its diagnosis are not specific. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261919PMC
October 2018
25 Reads

Post-operative complications of craniotomy and craniectomy.

Emerg Radiol 2019 Feb 25;26(1):99-107. Epub 2018 Sep 25.

Department of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, PO Box 648, Rochester, NY, 14642, USA.

Craniotomy and craniectomy are widely performed emergent neurosurgical procedures and are the prescribed treatment for a variety of conditions from trauma to cancer. It is vital for the emergency radiologist to be aware of expected neuroimaging findings in post-craniotomy and craniectomy patients in order to avoid false positives. It is just as necessary to be familiar with postsurgical complications in these patients to avoid delay in lifesaving treatment. Read More

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http://link.springer.com/10.1007/s10140-018-1647-2
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http://dx.doi.org/10.1007/s10140-018-1647-2DOI Listing
February 2019
46 Reads

Pitfalls in the Imaging Interpretation of Intracranial Hemorrhage.

Authors:
Humberto Morales

Semin Ultrasound CT MR 2018 Oct 3;39(5):457-468. Epub 2018 Aug 3.

Section of Neuroradiology, University of Cincinnati Medical Center, 234 Goodman St, Cincinnati, OH, 45267-0761. Electronic address:

Intracranial hemorrhage (ICH) is one of the most common pathologic findings in the emergent computed tomography (CT) imaging. ICH presents as hyperattenuation in parenchymal, subarachnoid, subdural, or epidural location. However, the initial interpretation of areas of hyperattenuation can be challenging as other pathologic or nonpathologic processes (eg, calcifications, vascular malformations, highly cellular tumors, iodinated contrast, or beam-hardening artifacts) can have similar appearance. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08872171183006
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http://dx.doi.org/10.1053/j.sult.2018.07.001DOI Listing
October 2018
20 Reads

Intracranial Hemorrhage Imaging.

Semin Ultrasound CT MR 2018 Oct 27;39(5):441-456. Epub 2018 Feb 27.

Department of Radiology, Stanford University School of Medicine, Stanford, CA.

Intracranial hemorrhage is a medical event frequently encountered in the clinical practice of radiology that has significant potential for patient morbidity and mortality. The expedient and accurate identification of intracranial hemorrhage as well as elucidation of the underlying cause can assist in optimizing the care of these patients. In this review, we attempt to familiarize the reader with the imaging appearance of multiple types of intracranial hemorrhage, both intra-axial and extra-axial and utilizing both computed tomography and magnetic resonance imaging, as well as to provide a framework for assessment of the underlying cause of the hemorrhage. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08872171183000
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http://dx.doi.org/10.1053/j.sult.2018.01.003DOI Listing
October 2018
36 Reads

Probable pathogenesis, diagnosis, and management of untreated arteriovenous malformation with cyst formation: case report and literature review.

Acta Neurol Belg 2018 Dec 21;118(4):603-605. Epub 2018 Sep 21.

Department of Neurosurgery, Chang Gung Memorial Hospital, Chang Gung University, No. 5 Fu-Shin Street, Gui-Shan Dist., Taoyuan, 33305, Taiwan, Republic of China.

Arteriovenous malformations (AVMs) usually manifest as headaches, seizures, focal neurological signs, and spontaneous intracerebral or subarachnoid hemorrhages. An untreated AVM with associated cyst formation is extremely rare, and the probable pathogenesis is unclear. We propose and discuss the possible pathogenesis of this condition and its diagnosis and management. Read More

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http://link.springer.com/10.1007/s13760-018-1011-z
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http://dx.doi.org/10.1007/s13760-018-1011-zDOI Listing
December 2018
13 Reads

Atypical chronological changes on neuroimaging in the epidermoid in the frontal lobe with intracystic hemorrhage and tumor growth: Case report.

Radiol Case Rep 2018 Dec 13;13(6):1133-1136. Epub 2018 Sep 13.

Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tenodai, Tsukuba, Ibaraki, 305-8575 Japan.

Intracranial epidermoids are rare lesions accounting for 0.2%-1.8% of all intracranial tumors. Read More

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http://dx.doi.org/10.1016/j.radcr.2018.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138860PMC
December 2018
9 Reads

Infundibuloneurohypophysitis associated with autoimmune thrombocytopenia and chiasmal syndrome: a case report.

Acta Neurol Belg 2019 Sep 20;119(3):337-342. Epub 2018 Aug 20.

Department of Neurology and Psychiatry, Neurosurgery, 'Sapienza' University of Rome, Rome, Italy.

Lymphocytic hypophysitis is an uncommon autoimmune disease. It may involve the adenohypophysis, neurohypophysis and pituitary stalk. It is most often encountered in pregnant women. Read More

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http://dx.doi.org/10.1007/s13760-018-1007-8DOI Listing
September 2019
12 Reads

Radiation-Induced Cerebral Microbleeds in Pediatric Patients With Brain Tumors Treated With Proton Radiation Therapy.

Int J Radiat Oncol Biol Phys 2018 12 6;102(5):1465-1471. Epub 2018 Aug 6.

Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana.

Purpose: Proton beam radiation therapy (PBT) has been increasingly used to treat pediatric brain tumors; however, limited information exists regarding radiation-induced cerebral microbleeds (CMBs) among these patients. The purpose of this study was to evaluate the incidence, risk factors, and imaging appearance of CMBs in pediatric patients with brain tumors treated with PBT.

Materials And Methods: A retrospective study was performed of 100 pediatric patients with primary brain tumors treated with PBT. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2018.07.2016DOI Listing
December 2018
5 Reads

One-year prognosis of non-traumatic cortical subarachnoid haemorrhage: A prospective series of 34 patients.

Neurologia 2018 Jun 11. Epub 2018 Jun 11.

Servicio de Neurología, Hospital La Fe, Valencia, España.

Introduction: Cortical subarachnoid haemorrhage (cSAH) has multiple aetiologies. No prospective study has reported the long-term progression of the condition. The objective of this study is to describe the clinical and aetiological characteristics of patients with cSAH and to gain insight into prognosis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02134853183002
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http://dx.doi.org/10.1016/j.nrl.2017.12.008DOI Listing
June 2018
61 Reads

[SPONTANEOUS PARENCHYMAL INTRACRANIAL HEMORRHAGE - A DIAGNOSTIC CHALLENGE].

Harefuah 2018 03;157(3):158-161

Department of Neurology, Hadassah Medical Center, Jerusalem Israel.

Introduction: Non-traumatic intracranial hemorrhage (ICH) is a devastating event associated with a high rate of morbidity and mortality. Patient age, hemorrhage location, number of foci, and underlying diseases are important clues to the etiology. Non-contrast head CT, given its availability and high sensitivity in detecting blood products, is frequently the first tool to readily detect ICH; however, different types of hemorrhages may share a common appearance on CT and the optimal therapeutic approach varies depending on etiology. Read More

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March 2018
15 Reads

Asymmetric and Symmetric Dimethylarginines are Markers of Delayed Cerebral Ischemia and Neurological Outcome in Patients with Subarachnoid Hemorrhage.

Neurocrit Care 2018 08;29(1):84-93

Institute of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Background: Delayed cerebral ischemia (DCI) is the major cause of lethality and neuronal damage in patients who survived the primary subarachnoid hemorrhage (SAH). Asymmetric and symmetric dimethylarginines (ADMA and SDMA) inhibit nitric oxide production from L-arginine via distinct mechanisms. Elevated ADMA levels are associated with vasospasm after SAH. Read More

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http://dx.doi.org/10.1007/s12028-018-0520-1DOI Listing
August 2018
6 Reads

Cerebral Microbleeds: Imaging and Clinical Significance.

Radiology 2018 Apr;287(1):11-28

From the Affidea Centre de Diagnostic Radiologique de Carouge (CDRC), Geneva, Switzerland (S.H.); Faculty of Medicine, University of Geneva, Geneva, Switzerland (S.H.); Department of Surgical Sciences, Radiology, Uppsala University, Uppsala, Sweden (S.H., E.M.L.); Department of Neuroradiology, University Hospital Freiburg, Freiburg, Germany (S.H.); Department of Radiology and Nuclear Medicine and Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands (M.W.V.); Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, the Netherlands (J.P.A.K., F.B.); Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, Institute of Neurology, University College London, London, England (H.R.J., F.B.).

Cerebral microbleeds (CMBs), also referred to as microhemorrhages, appear on magnetic resonance (MR) images as hypointense foci notably at T2*-weighted or susceptibility-weighted (SW) imaging. CMBs are detected with increasing frequency because of the more widespread use of high magnetic field strength and of newer dedicated MR imaging techniques such as three-dimensional gradient-echo T2*-weighted and SW imaging. The imaging appearance of CMBs is mainly because of changes in local magnetic susceptibility and reflects the pathologic iron accumulation, most often in perivascular macrophages, because of vasculopathy. Read More

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http://dx.doi.org/10.1148/radiol.2018170803DOI Listing
April 2018
28 Reads

Diagnosing Neoplastic Hematoma: Role of MR Perfusion.

Clin Neuroradiol 2019 Jun 7;29(2):263-268. Epub 2018 Feb 7.

Department of Pathology, Dalhousie University, Halifax, Canada.

Background: The imaging appearance of neoplastic hematoma can be complicated by the presence of a large hematoma, even on magnetic resonance imaging (MRI). We describe the role of MR perfusion (MRP) in detecting neoplastic hematomas in patients with intraparenchymal hematoma (IPH).

Material And Methods: A retrospective review was performed for consecutive patients with IPH, where MRP was performed. Read More

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http://link.springer.com/10.1007/s00062-018-0664-6
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http://dx.doi.org/10.1007/s00062-018-0664-6DOI Listing
June 2019
22 Reads

Evaluation of lymphatic vessel dilatations by anterior segment swept-source optical coherence tomography: case report.

BMC Ophthalmol 2017 Oct 23;17(1):194. Epub 2017 Oct 23.

Faculty of Medicine Department of Ophthalmology, Semmelweis University, Budapest, Hungary.

Background: Conjunctival lymphangiectasia is a rare condition presumably caused by the obstruction of lymphatic channels or by an abnormal connection between conjunctival lymphatic and blood vessels. Diagnosis is based on clinical appearance and histology. We report a case of conjunctival lymphangiectasia in which anterior segment optical coherence tomography (OCT) was used to assist the diagnosis and the planning of the biopsy location. Read More

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http://dx.doi.org/10.1186/s12886-017-0588-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654095PMC
October 2017
16 Reads

Initial Investigation into Microbleeds and White Matter Signal Changes following Radiotherapy for Low-Grade and Benign Brain Tumors Using Ultra-High-Field MRI Techniques.

AJNR Am J Neuroradiol 2017 Dec 28;38(12):2251-2256. Epub 2017 Sep 28.

From the Departments of Medical Biophysics (J.-G.B., G.S.B., R.S.M.)

Background And Purpose: External beam radiation therapy is a common treatment for many brain neoplasms. While external beam radiation therapy adheres to dose limits to protect the uninvolved brain, areas of high dose to normal tissue still occur. Patients treated with chemoradiotherapy can have adverse effects such as microbleeds and radiation necrosis, but few studies exist of patients treated without chemotherapy. Read More

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http://dx.doi.org/10.3174/ajnr.A5395DOI Listing
December 2017
6 Reads

Post-traumatic seizure with an unexpected finding.

Arch Dis Child Educ Pract Ed 2018 12 22;103(6):302-303. Epub 2017 Sep 22.

Department of Paediatric Neurology, Child Development Centre, Addenbrooke's Hospital, Cambridge, UK.

A 5-year-old boy of non-consanguineous Indian descent presented to the emergency department (ED) following a prolonged seizure, preceded by a minor head injury from a low-level unwitnessed fall. The seizure was described as focal with head and neck version to the right. There was urinary and faecal incontinence and foaming at the mouth. Read More

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http://dx.doi.org/10.1136/archdischild-2017-313314DOI Listing
December 2018
2 Reads

Status Epilepticus Secondary to Pseudonodular Hemorragic Occipital Lesion with Edema: "Non Semper Ea Sunt, Quae Videntur, Decipit Frons Prima Multos" (Things Are Not Always What They Seem; The First Appearance Deceives Many).

World Neurosurg 2017 Aug 27;104:1044.e1-1044.e3. Epub 2017 May 27.

Department of Neurosurgery, Institute for Scientific and Care Research, Main Hospital of Santa Maria Nuova, Reggio Emilia, Italy; Neurosurgery-Neurotraumatology Unit, University Hospital of Parma, Parma, Italy.

We report a case in which common radiologic images masked a rare case of supratentorial hemangioblastoma (HBL). Other peculiarities of this case are the clinical presentation with status epilepticus and the occurrence of a supratentorial HBL unrelated to von Hippel-Lindau syndrome. Based on clinical and radiologic findings, including massive cerebral edema and hemorrhagic presentation, our preoperative diagnosis was a cerebral metastasis. Read More

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http://dx.doi.org/10.1016/j.wneu.2017.05.114DOI Listing
August 2017
27 Reads

Characterization of a novel murine model for spontaneous hemorrhagic stroke using in vivo PET and MR multiparametric imaging.

Neuroimage 2017 07 1;155:245-256. Epub 2017 May 1.

Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tuebingen, Tuebingen, Germany. Electronic address:

The clinical use of Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) has proven to be a strong diagnostic tool in the field of neurology. The reliability of these methods to confirm clinical diagnoses has guided preclinical research to utilize these techniques for the characterization of animal disease models. Previously, we demonstrated that an endothelial cell-specific ablation of the murine Serum Response Factor (Srf) results in blood brain barrier (BBB) breakdown and hemorrhagic stroke. Read More

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http://dx.doi.org/10.1016/j.neuroimage.2017.04.071DOI Listing
July 2017
35 Reads

Early appearance of tuberous sclerosis complex on cerebral ultrasound in extremely preterm infant.

J Neonatal Perinatal Med 2017 ;10(2):203-206

Department of Paediatrics, Section Neonatology, Amalia Children Hospital, Radboud University Medical Centre Nijmegen, Nijmegen, The Netherlands.

Tuberous sclerosis complex (TSC) is an inherited neurocutaneous disorder. Diagnosis of early onset TSC in newborn infants is usually made by cardiac ultrasound because of circulatory problems due to cardiac rhabdomyoma. Early appearance of cortical tubers on cerebral ultrasound in newborn infants is very rare. Read More

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http://dx.doi.org/10.3233/NPM-171652DOI Listing
May 2018
25 Reads

[A clinical analysis of 5 patients with infratentorial primary angiitis of central nervous system].

Zhonghua Nei Ke Za Zhi 2017 Apr;56(4):284-289

Department of Neurology, Navy General Hospital, Beijing 100048, China.

To explore the clinical characteristics of infratentorial primary angiitis in central nervous system(PACNS). A total of 5 cases diagnosed as infratentorial PACNS in the neurology department of Navy General Hospital of PLA in 2015 were enrolled in the study. The clinical, imaging and pathological data were collected and analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0578-1426.2017.04.009DOI Listing
April 2017
9 Reads

Cytotoxic Lesions of the Corpus Callosum That Show Restricted Diffusion: Mechanisms, Causes, and Manifestations.

Radiographics 2017 Mar-Apr;37(2):562-576. Epub 2017 Feb 6.

From the Department of Radiology, St Luke's International Hospital, 9-1 Akashicho, Chuo, Tokyo 104-8560, Japan (J.S., N.K., Y.N.); and the Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, Iowa (T.M.).

Cytotoxic lesions of the corpus callosum (CLOCCs) are secondary lesions associated with various entities. CLOCCs have been found in association with drug therapy, malignancy, infection, subarachnoid hemorrhage, metabolic disorders, trauma, and other entities. In all of these conditions, cell-cytokine interactions lead to markedly increased levels of cytokines and extracellular glutamate. Read More

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http://dx.doi.org/10.1148/rg.2017160085DOI Listing
October 2017
95 Reads

Evolution of cerebral microbleeds after cranial irradiation in medulloblastoma patients.

Neurology 2017 Feb 25;88(8):789-796. Epub 2017 Jan 25.

From The Hemorrhagic Stroke Research Program (D.R., A.C., L.X., A.V., S.M.-R., A.V.), J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Department of Medicine (D.R.), Faculty of Medicine, Naresuan University, Phitsanulok, Thailand; Image Sciences Institute (H.J.K.), University Medical Center Utrecht, the Netherlands; Department of Radiation Oncology (H.A.S.), Massachusetts General Hospital, Boston; and Department of Neurology (C.M.G., J.D.), Division of Neuro-Oncology, Massachusetts General Hospital Cancer Center, and Center for Regenerative Medicine, Harvard Medical School, Boston.

Objective: To characterize the temporal and spatial pattern of cerebral microbleeds (CMBs) after cranial irradiation in patients with medulloblastoma.

Methods: We retrospectively identified patients with medulloblastoma treated with craniospinal irradiation at the Massachusetts General Hospital between 1999 and 2015. Longitudinal MRI including T2*-weighted gradient-recalled echo (GRE) sequences were reviewed, and the prevalence, spatial pattern, and risk factors associated with CMBs were characterized. Read More

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http://dx.doi.org/10.1212/WNL.0000000000003631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344076PMC
February 2017
22 Reads
1 Citation
8.290 Impact Factor

Mantle Cell Lymphoma with Central Nervous System Involvement Simulating Bilateral Subdural Hematomas.

World Neurosurg 2017 Mar 4;99:808.e1-808.e2. Epub 2017 Jan 4.

Department of Pathology, Hospital General Universitario de Castellón, Castellón, Spain.

We describe a 71-year-old-patient receiving antiplatelet therapy and being attended by emergency medical services for psychomotor retardation and gait disturbance. An emergency computed tomographic scan showed a bilateral subacute hematoma. The patient reported a fall 2 weeks earlier. Read More

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http://dx.doi.org/10.1016/j.wneu.2016.12.122DOI Listing
March 2017
4 Reads

Goggle-like Appearance of Injured Cerebellothalamic Axons Surrounding Red Nuclei in Holmes Tremor.

Can J Neurol Sci 2017 Jul 15;44(4):429-431. Epub 2016 Dec 15.

4Department of Neurology,University of Minnesota,Minneapolis,Minnesota.

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http://dx.doi.org/10.1017/cjn.2016.418DOI Listing
July 2017
34 Reads
1.600 Impact Factor

Dual-Energy CT in Emergency Neuroimaging: Added Value and Novel Applications.

Radiographics 2016 Nov-Dec;36(7):2186-2198

From the Department of Radiology, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115.

Dual-energy computed tomography (CT) is a powerful diagnostic tool that is becoming more widely clinically available. Dual-energy CT has the potential to aid in the detection or add diagnostic confidence in the evaluation of a variety of emergent neurologic conditions with use of postprocessing techniques that allow one to take advantage of the different x-ray energy-dependent absorption behaviors of different materials. Differentiating iodine from hemorrhage may help in delineating CT angiographic spot signs, which are small foci of intracranial hemorrhage seen on CT angiograms in cases of acute hemorrhage. Read More

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http://dx.doi.org/10.1148/rg.2016160069DOI Listing
September 2017
15 Reads

Magnetic Resonance Imaging Characteristics of Hyperacute Intracerebral Hemorrhage.

J Vasc Interv Neurol 2016 Oct;9(2):10-13

Department of Neurology, University of Tennessee Health Sciences Center, Memphis, TN, USA.

Background: Magnetic resonance imaging (MRI) of the brain is highly sensitive for detecting intracerebral hemorrhage (ICH). Understanding of the imaging characteristics of hyperacute ICH is limited secondary to availability and increased time to scan relative to other imaging modalities.

Objective: In this report, we present the MRI characteristics of two patients who developed ICH while on the MRI table. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094255PMC
October 2016
13 Reads

Magnetic Resonance Imaging Appearance and Mechanism of Action of Five Hemostatic Agents Used in Neurosurgery.

Vet Surg 2016 Nov 23;45(8):996-1004. Epub 2016 Sep 23.

Department of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado.

Objective: To describe the magnetic resonance (MR) image appearance of 5 hemostatic agents placed in the brain, and to review their clinical application.

Study Design: Descriptive ex vivo and in vivo study.

Animals: Canine cadavers (n=4), client-owned dogs (n=4). Read More

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http://dx.doi.org/10.1111/vsu.12551DOI Listing
November 2016
33 Reads

Evolution of Subarachnoid Hemorrhage Extension in Lobar Hemorrhage in the Early Chronic Phase and the Impact on Cerebral Amyloid Angiopathy Criteria.

J Stroke Cerebrovasc Dis 2016 Oct 16;25(10):2502-5. Epub 2016 Aug 16.

Department of Neurology, Hôpital Caremeau, CHU Nîmes, Nîmes Cedex 4, France; Institut de Génomique Fonctionnelle, UMR5203, Université Montpellier, Montpellier, France.

Background: Subarachnoid hemorrhage extension (SAHE) in acute lobar hemorrhage (LH) is frequent. Little is known about the short- and medium-term radiological evolution of SAHE. Our aim was to study this evolution by magnetic resonance imaging (MRI). Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.06.026DOI Listing
October 2016
9 Reads

Clinical characteristics and risk factors of Intracranial hemorrhage in patients following allogeneic hematopoietic stem cell transplantation.

Ann Hematol 2016 Oct 3;95(10):1637-43. Epub 2016 Aug 3.

Peking University People's Hospital, Institute of Hematology, Beijing Key Laboratory of HSCT, No. 11, Xizhimen South Street, Xicheng District, Beijing, 100044, China.

Intracranial hemorrhage (ICH) is one of the most life-threatening neurological complications after allogeneic hematopoietic stem cell transplantation. Although cerebral complications and its causes after allo-HSCT are well documented, assessment of the incidence and risk factors of intracranial hemorrhage following allo-HSCT are less discussed. A nested case-control study was conducted involving 160 subjects drawn from 2169 subjects who underwent HSCT at Peking University People's Hospital between 2004 and 2014. Read More

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http://dx.doi.org/10.1007/s00277-016-2767-yDOI Listing
October 2016
39 Reads
1 Citation
2.634 Impact Factor

Ischemic pituitary adenoma apoplexy-Clinical appearance and prognosis after surgical intervention.

Clin Neurol Neurosurg 2016 Sep 7;148:142-6. Epub 2016 Jul 7.

Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, Japan.

Background: Several retrospective investigations have recommended more passive surgical indications for intratumoral hemorrhage of pituitary adenomas due to probable spontaneous resolution. However, no definitive analyses have compared pituitary adenomas with hemorrhagic apoplexy and intratumoral hemorrhage without evident apoplectic symptoms or pituitary adenoma infarction.

Methods: This study retrospectively identified 43 patients with symptomatic pituitary apoplexy among 1067 patients with pituitary adenomas initially treated by surgery at a single institute between April 2005 and May 2015, with 27 cases of hemorrhagic (2. Read More

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http://dx.doi.org/10.1016/j.clineuro.2016.07.013DOI Listing
September 2016
90 Reads

Cerebral cavernous malformations with diffuse manifestation: A benign entity?

J Neurol Sci 2016 Aug 15;367:335-41. Epub 2016 Jun 15.

Department of Neurological Surgery, Juntendo University Urayasu Hospital, Urayasu, Chiba, Japan.

Purpose: Cerebral cavernous malformations (CCMs) are a distinct cerebrovascular disease. A fraction of CCMs present as diffuse manifestations distributed over the cerebral hemispheres, cerebellum, and brainstem. The purpose of the present study was to explore the clinical picture of such CCMs. Read More

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http://dx.doi.org/10.1016/j.jns.2016.06.012DOI Listing
August 2016
11 Reads

Combined 3 Tesla MRI Biomarkers Improve the Differentiation between Benign vs Malignant Single Ring Enhancing Brain Masses.

PLoS One 2016 13;11(7):e0159047. Epub 2016 Jul 13.

Department of Neurosciences, Imaging and Clinical Sciences, University "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy.

Purpose: To evaluate whether the combination of imaging biomarkers obtained by means of different 3 Tesla (3T) Magnetic Resonance Imaging (MRI) advanced techniques can improve the diagnostic accuracy in the differentiation between benign and malignant single ring-enhancing brain masses.

Materials And Methods: 14 patients presenting at conventional 3T MRI single brain mass with similar appearance as regard ring enhancement, presence of peri-lesional edema and absence of hemorrhage signs were included in the study. All lesions were histologically proven: 5 pyogenic abscesses, 6 glioblastomas, and 3 metastases. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159047PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943588PMC
July 2017
14 Reads

Application value of magnetic resonance imaging in diagnosing central nervous system lymphoma.

Pak J Med Sci 2016 Mar-Apr;32(2):389-93

Mingming Zhang, Department of Radiology, Binzhou People's Hospital, Binzhou, Shandong, 256610, China.

Objective: To describe the magnetic resonance imaging (MRI) appearance of central nervous system lymphoma.

Methods: We retrospectively reviewed MRI images of 40 patients who had pathologically proven primary central nervous system lymphoma (PCNSL) and received treatment in Binzhou People's Hospital, Shandong, China from January to December in 2014. Location, size and form of tumor was observed and relevant data were recorded for analysis. Read More

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http://dx.doi.org/10.12669/pjms.322.9013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859029PMC
May 2016
2 Reads

Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study.

Lancet Neurol 2016 07 11;15(8):811-819. Epub 2016 May 11.

Hemorrhagic Stroke Research Group, Massachusetts General Hospital, Boston, MA, USA.

Background: Loss of cortical grey matter is a diagnostic marker of many neurodegenerative diseases, and is a key mediator of cognitive impairment. We postulated that cerebral amyloid angiopathy (CAA), characterised by cortical vascular amyloid deposits, is associated with cortical tissue loss independent of parenchymal Alzheimer's disease pathology. We tested this hypothesis in patients with hereditary cerebral haemorrhage with amyloidosis-Dutch type (HCHWA-D), a monogenetic disease with minimal or no concomitant Alzheimer's disease pathology, as well as in patients with sporadic CAA and healthy and Alzheimer's disease controls. Read More

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http://dx.doi.org/10.1016/S1474-4422(16)30030-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248657PMC
July 2016
60 Reads

Clinical Deterioration and Early Imaging Changes after Intravenous Tissue Plasminogen Activator Administration in Acute Ischemic Stroke Patients.

J Stroke Cerebrovasc Dis 2016 Jul 25;25(7):1823-1827. Epub 2016 Apr 25.

Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, Ohio.

Background And Purpose: Clinical worsening is a known complication following acute ischemic stroke. This study attempted to determine the mechanism of deterioration by correlating clinical findings with changes on computed tomography or magnetic resonance.

Methods: From a single university medical center, 30 consecutive acute ischemic stroke patients who received intravenous tissue plasminogen activator within 3 hours of symptom onset during a 3-year period were identified from a quality database that included all hospitalized patients either admitted with strokes or with in-hospital strokes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10523057160015
Publisher Site
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.03.016DOI Listing
July 2016
9 Reads