3,716 results match your criteria Brain Injury[Journal]


Longitudinal examination of the relationship between changes in white matter organization and cognitive outcome in chronic TBI.

Brain Inj 2019 Apr 24:1-8. Epub 2019 Apr 24.

b Kessler Foundation , East Hanover , NJ , USA.

Background And Objective: Changes in cerebral white matter organization have been documented in acute phases of recovery from traumatic brain injury (TBI). However, little is known about reorganization processes in more chronic stages of recovery. The current study identified changes in white matter organization in chronic cases of TBI, and determined the relationship between structural changes and cognitive functioning. Read More

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http://dx.doi.org/10.1080/02699052.2019.1606449DOI Listing

Validity of the CES-D for depression screening in military service members with a history of mild traumatic brain injury.

Brain Inj 2019 Apr 24:1-9. Epub 2019 Apr 24.

b Defense and Veterans Brain Injury Center (DVBIC) San Antonio VA Polytrauma Rehabilitation Center, South Texas Veterans Healthcare System , San Antonio , Texas , USA.

Primary Objective: To advance knowledge about the value of the Center for Epidemiologic Studies - Depression scale (CES-D) for depression screening in military service members with a history of mild traumatic brain injury (mTBI).

Research Design: Retrospective data from 336 military service members with a history of mTBI were extracted from a TBI Repository at a large military medical center. Participants included in this study screened positive for mTBI in a primary care clinic or soldier readiness processing center and were enrolled in the TBI repository from November 6, 2014 to May 31, 2017. Read More

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http://dx.doi.org/10.1080/02699052.2019.1610191DOI Listing

Loss of consciousness and altered mental state predicting depressive and post-concussive symptoms after mild traumatic brain injury.

Brain Inj 2019 Apr 24:1-6. Epub 2019 Apr 24.

f Department of Emergency Medicine , University of Michigan Medical School , Ann Arbor , MI , USA.

Objective: Limited studies exist on the association between loss of consciousness (LOC) and altered mental state (AMS) and development of depressive and post-concussive symptoms within six months after mild traumatic brain injury (mTBI). We tested the hypothesis that presence of both LOC and AMS predict the highest risk of symptoms within the first six months post-mTBI compared to either variable alone, and that LOC alone is more strongly associated with these symptoms.

Research Design: We analyzed data from 407 subjects with mTBI from the Head injury Serum Markers for Assessing Response to Trauma (HeadSMART) cohort, a prospective cohort of patients post-TBI presenting to two urban emergency departments. Read More

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http://dx.doi.org/10.1080/02699052.2019.1606447DOI Listing

Longitudinal patterns of behavior, cognition, and quality of life after mild traumatic brain injury in children: BIONIC study findings.

Brain Inj 2019 Apr 23:1-10. Epub 2019 Apr 23.

e BIONIC Study Group members listed below.

Background: Research following mild traumatic brain injury (mTBI) during childhood predominantly examines recovery up to 12 months post-injury.

Objectives: To determine children's longer-term (4 years) patterns and predictors of recovery.

Methods: Parents of 196 children (aged 1-15 years) completed the Behaviour Assessment System for Children and Pediatric Quality of Life Inventory at baseline, 1, 6, 12, and 48 months post-injury. Read More

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http://dx.doi.org/10.1080/02699052.2019.1606445DOI Listing

Seizure frequency in patients with isolated subdural hematoma and preserved consciousness.

Brain Inj 2019 Apr 21:1-5. Epub 2019 Apr 21.

d Department of Emergency Medicine , Massachusetts General Hospital , Boston , MA , USA.

Background: Seizures are a complication of subdural hematoma (SDH), and there is substantial variability in the use of seizure prophylaxis for patients with SDH. However, the incidence of seizures in patients with SDH without severe neurotrauma is not clear. The objective of this study was to assess the frequency of and factors associated with seizures in patients with isolated SDH (iSDH) without severe neurotrauma. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1606446DOI Listing
April 2019
1 Read

Why do people misunderstand stroke symptoms? How background knowledge affects causal attributions for ambiguous stroke symptoms.

Brain Inj 2019 Apr 21:1-8. Epub 2019 Apr 21.

b School of Psychology , Victoria University of Wellington , Wellington , New Zealand.

Primary Objective: People often misattribute stroke survivors' symptoms to other causes such as their personality, especially when the survivors are young. As a result, these stroke survivors experience feelings of resentment towards and from their acquaintances, and may struggle to retain employment. This study aimed to clarify how people's misattributions for stroke symptoms were affected by varying information about the stroke. Read More

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http://dx.doi.org/10.1080/02699052.2019.1606451DOI Listing

Clinical correlates of noise sensitivity in patients with acute TBI.

Brain Inj 2019 Apr 21:1-9. Epub 2019 Apr 21.

a Department of Psychology , Auckland University of Technology , Auckland , New Zealand.

Primary Objective: The impact of noise sensitivity (NS) on the daily functioning of people who have experienced a traumatic brain injury (mTBI) is an understudied area, particularly following mTBI. The primary objective of this cross-sectional study was to investigate clinical markers of NS in a sample of New Zealand adults following mTBI.

Research Design: Cross-sectional study. Read More

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http://dx.doi.org/10.1080/02699052.2019.1606443DOI Listing

Location of traumatic brain injury-related deaths: epidemiological analysis of 11 European countries.

Brain Inj 2019 Apr 21:1-6. Epub 2019 Apr 21.

a Department of Public Health, Faculty of Health Sciences and Social Work , Trnava University , Trnava , Slovak Republic.

Background: Understanding the factors related to traumatic brain injury (TBI)-related mortality is important in obtaining a complete picture of the predictors and burden of injury-related deaths.

Objective: To analyze deaths due to TBI occurring inside versus outside hospitals.

Methods: Data were obtained by requests to the representatives of national statistical offices and health administration institutions for one reported calendar year (2014 or the nearest available year). Read More

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http://dx.doi.org/10.1080/02699052.2019.1605622DOI Listing

External causes of death after severe traumatic brain injury in a multicentre inception cohort: clinical description and risk factors.

Brain Inj 2019 Apr 8:1-9. Epub 2019 Apr 8.

a Liverpool Brain Injury Rehabilitation Unit , Liverpool Hospital , Sydney , New South Wales , Australia.

Objective: To characterize the clinical profile of patients dying from external causes (EC) following severe traumatic brain injury (TBI).

Design And Methods: Data from 2545 patients forming the NSW-BIRP inception cohort discharged from post-acute inpatient rehabilitation between 1 July 1990 and 1 October 2007 were retrospectively reviewed. Standardized mortality ratios (SMRs) were calculated for EC sub-categories. Read More

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http://dx.doi.org/10.1080/02699052.2019.1600020DOI Listing
April 2019
1 Read

GLP-1's role in neuroprotection: a systematic review.

Brain Inj 2019 Apr 2:1-85. Epub 2019 Apr 2.

a School of Medicine , Koç University , Istanbul , Turkey.

Glucagon-like peptide 1 (GLP-1) is a target for treatment of diabetes; however, its function in the brain is not well studied. In this systematic review, we aimed to analyze the neuroprotective role of GLP-1 and its defined mechanisms.

Methods: We searched 'Web of Science' and 'Pubmed' to identify relevant studies using GLP-1 as the keyword. Read More

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http://dx.doi.org/10.1080/02699052.2019.1587000DOI Listing
April 2019
2 Reads

Attention and visuo-spatial function in children without cerebral palsy who were cooled for neonatal encephalopathy: a case-control study.

Brain Inj 2019 Mar 29:1-5. Epub 2019 Mar 29.

d Translational Health Sciences, Bristol Medical School, St Michael's Hospital , University of Bristol , UK.

Objectives: Dorsal-stream functions are vulnerable to early brain injury associated with neonatal encephalopathy (NE) following perinatal asphyxia, even in children not developing cerebral palsy (CP). Since therapeutic hypothermia (TH) became the standard treatment for NE, the incidence of CP is reduced but the impact on dorsal-stream functions is unknown. We aimed to compare dorsal-stream functions in TH-treated survivors of NE, without CP, with those of matched controls. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1597163DOI Listing
March 2019
3 Reads

Emotion regulation after acquired brain injury: a study of heart rate variability, attentional control, and psychophysiology.

Brain Inj 2019 Mar 23:1-9. Epub 2019 Mar 23.

b Ferkauf Graduate School of Psychology , Albert Einstein College of Medicine Yeshiva University , New York , NY , USA.

Primary Objective: To examine the efficacy of heart rate variability biofeedback (HRV-BF) to treat emotional dysregulation in persons with acquired brain injury.

Design: A secondary analysis of a quasi-experimental study which enrolled 13 individuals with severe chronic acquired brain injury participating in a community-based programme. Response-to-treatment was measured with two HRV resonance indices (low frequency activity [LF] and low frequency/high frequency ratio [LF/HF]). Read More

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http://dx.doi.org/10.1080/02699052.2019.1593506DOI Listing
March 2019
1 Read

MRS and DTI evidence of progressive posterior cingulate cortex and corpus callosum injury in the hyper-acute phase after Traumatic Brain Injury.

Brain Inj 2019 Mar 8:1-15. Epub 2019 Mar 8.

a FMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences , University of Oxford , Oxford , United Kingdom.

The posterior cingulate cortex (PCC) and corpus callosum (CC) are susceptible to trauma, but injury often evades detection. PCC Metabolic disruption may predict CC white matter tract injury and the secondary cascade responsible for progression. While the time frame for the secondary cascade remains unclear in humans, the first 24 h (hyper-acute phase) are crucial for life-saving interventions. Read More

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http://dx.doi.org/10.1080/02699052.2019.1584332DOI Listing

Variability in daily self-reported emotional symptoms and fatigue measured over eight weeks in community dwelling individuals with traumatic brain injury.

Brain Inj 2019 5;33(5):567-573. Epub 2019 Mar 5.

e Department of Physical Medicine and Rehabilitation , University of Pittsburgh , Pittsburgh , PA , USA.

Objective: To investigate within-person variability in daily self-reported emotional and fatigue symptoms and factors associated with high within-person variability among individuals with chronic traumatic brain injury (TBI).

Design: This was a prospective descriptive pilot study of n = 18 adults with chronic TBI (2-27 years post-injury) who owned and could independently use an Apple or Android device.

Methods: Participants completed daily assessments for 8 weeks via smartphone. Read More

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http://dx.doi.org/10.1080/02699052.2019.1584333DOI Listing
March 2019
4 Reads

Examining the relationship between neuroticism and post-concussion syndrome in mild traumatic brain injury.

Brain Inj 2019 Feb 27:1-9. Epub 2019 Feb 27.

d Department of Psychology , Saint Louis University , St. Louis , MO , USA.

Objective: We sought to examine the relationship between personality traits and post-concussion symptom reporting in individuals with and without a self-reported history of concussion.

Methods: Data were collected via a cross-sectional electronic survey from 619 individuals via Amazon Mechanical Turk (mTurk). Participants completed a background demographic questionnaire, as well as both the Post-Concussion Symptom Scale (PCSS) and IPIP-NEO-120 personality inventory. Read More

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http://dx.doi.org/10.1080/02699052.2019.1581949DOI Listing
February 2019
2 Reads

A new global health outcome score after trauma (GHOST) for disability, cognitive impairment, and health-related quality of life: data from a prospective cross-sectional observational study.

Brain Inj 2019 Feb 27:1-10. Epub 2019 Feb 27.

a CINTESIS - Center for Health Technology and Services Research, Faculty of Medicine , University of Porto , Porto , Portugal.

Background: Trauma patients experience morbidity related to disability and cognitive impairment that negatively impact their health-related quality of life (HRQoL). We assessed the impact of trauma on disability, cognitive impairment and HRQoL after intensive care in patients with and without traumatic brain injury (TBI) and created a predictive score to identify patients with worse outcome.

Methods: We identified 262 patients with severe trauma (ISS>15) admitted to the emergency room of a level 1 trauma center. Read More

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http://dx.doi.org/10.1080/02699052.2019.1581257DOI Listing
February 2019

Patterns of early conversational recovery for people with traumatic brain injury and their communication partners.

Brain Inj 2019 23;33(5):690-698. Epub 2019 Feb 23.

a Discipline of Speech Pathology, Faculty of Health Sciences , University of Sydney , Lidcombe, NSW , Australia.

Primary Objective: To investigate whether the degree of participation by people with severe Traumatic Brain Injury (TBI), and the degree of support by their communication partners (CPs) changes in conversation during subacute recovery.

Methods And Procedures: Seventeen pairs of participants with TBI and their CPs were video-recorded during a 10 min casual conversation at 3 and 6 months post-injury. Communication behaviors were rated using the adapted Measure of Participation in Conversation (MPC) and the adapted Measure of Support in Conversation (MSC) at both time points and compared. Read More

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http://dx.doi.org/10.1080/02699052.2019.1571632DOI Listing
February 2019
1 Read

NFL blood levels are moderated by subconcussive impacts in a cohort of college football players.

Brain Inj 2019 11;33(4):456-462. Epub 2019 Jan 11.

d Department of Neuroscience , Lewis Katz School of Medicine at Temple University , Philadelphia , PA , USA.

Introduction: Repetitive subconcussive head impacts in contact/collision sports such as in US football are believed to contribute to long-term brain changes and chronic symptoms. However, the lack of tools to measure the effects of repeated subconcussion limits our understanding of potential contributions to neuropathological alterations including cellular damage.

Methods: We examined subconcussive head impacts using an accelerometer-embedded mouthguard on changes in blood levels of neurofilament light (NFL) chain in 18 Division I college football players. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1565895DOI Listing
January 2019
5 Reads

Autonomic impairment of patients in coma with different Glasgow coma score assessed with heart rate variability.

Brain Inj 2019 12;33(4):496-516. Epub 2019 Feb 12.

g Institute of Basic and Preclinical Sciences, "Victoria de Girón" , Havana , Cuba.

Primary Objective: The objective of this study is to assess the functional state of the autonomic nervous system in healthy individuals and in individuals in coma using measures of heart rate variability (HRV) and to evaluate its efficiency in predicting mortality.

Design And Methods: Retrospective group comparison study of patients in coma classified into two subgroups, according to their Glasgow coma score, with a healthy control group. HRV indices were calculated from 7 min of artefact-free electrocardiograms using the Hilbert-Huang method in the spectral range 0. Read More

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http://dx.doi.org/10.1080/02699052.2018.1553312DOI Listing
February 2019
2 Reads
1.861 Impact Factor

Safety and feasibility of minocycline in treatment of acute traumatic brain injury.

Brain Inj 2019 12;33(5):679-689. Epub 2019 Feb 12.

a Department of Physical Medicine and Rehabilitation-Oakwood, School of Medicine , Wayne State University , Taylor , MI , USA.

Background: Minocycline is a pleomorphic neuroprotective agent well studied in animal models of traumatic brain injury (TBI) and brain ischemia.

Methods: To test the hypothesis that administration of minocycline in moderate to severe TBI (Glasgow Coma Score 3-12). Fifteen patients were enrolled in a two-dose escalation study of minocycline to evaluate the safety of twice the recommended antibiotic dosage; tier 1 n = 7 at a loading dose of 800 mg followed by 200 mg twice a day (BID) for 7 days; tier 2 n = 8 at a loading dose of 800 mg followed by 400 mg BID for 7 days. Read More

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http://dx.doi.org/10.1080/02699052.2019.1566968DOI Listing
February 2019

An examination of financial capacity and neuropsychological performance in chronic acquired brain injury (CABI).

Brain Inj 2019 Feb 3:1-12. Epub 2019 Feb 3.

c Psychology Department , Drexel University , Philadelphia , Pennsylvania , USA.

Primary Objective: Financial Capacity (FC) is known to be impaired in the acute and subacute stages of brain injury. The current study sought to examine FC in the context of chronic, moderate to severe acquired brain injury (CABI).

Research Design: The Financial Competence Assessment Inventory (FCAI), developed in Australia, was adapted to examine the integrity of FC in an American sample. Read More

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http://dx.doi.org/10.1080/02699052.2019.1570340DOI Listing
February 2019
3 Reads

Exploratory study of sport-related concussion effects on peripheral micro-RNA expression.

Brain Inj 2019 31;33(4):1-7. Epub 2019 Jan 31.

d Department of Community Health and Family Medicine , University of Florida , Gainesville , FL , USA.

Objective: Explore changes in micro-RNA (miRNA) expression in blood after sport-related concussion (SRC) in collegiate athletes.

Methods: Twenty-seven collegiate athletes (~41% male, ~75% white, age 18.8 ± 0. Read More

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http://dx.doi.org/10.1080/02699052.2019.1573379DOI Listing
January 2019
3 Reads

Collegiate student-athlete sex, years of sport eligibility completed, and sport contact level influence on concussion reporting intentions and behaviours.

Brain Inj 2019 31;33(5):592-597. Epub 2019 Jan 31.

a Department of Kinesiology, Concussion Research Laboratory , University of Georgia , Athens , GA , USA.

Primary Objective: The objective of this study was to determine whether sex, years of sport eligibility completed, and sport contact level influenced student-athletes' concussion reporting intentions and behaviours.

Research Design: Cross-sectional.

Methods And Procedures: Student-athletes (n = 828) reported their sex, years of sport eligibility completed, sport, and completed concussion reporting intentions and behaviours surveys. Read More

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http://dx.doi.org/10.1080/02699052.2019.1568573DOI Listing
January 2019
1 Read

Vocabulary skills of school-age children with acquired brain injury: an exploration of tiered word knowledge and naming errors.

Brain Inj 2019 31;33(5):657-669. Epub 2019 Jan 31.

a Discipline of Speech Pathology, Faculty of Health Sciences , University of Sydney , Lidcombe , Australia.

Background: Vocabulary deficits are the most frequently documented communication difficulty following childhood acquired brain injury (ABI). Given the adverse consequences of limited vocabulary on academic success, it is critical to identify the presence and nature of vocabulary impairments to provide effective intervention for children with ABI.

Method: Eleven children (7;6-11;11) with moderate/severe ABI (>12 months post-injury) and individually matched typically developing (TD) controls completed an Australian adaptation of a vocabulary assessment based on a three-tiered framework: tier 1 (basic words), tier 2 (high-frequency, cross-curricular words), and tier 3 (curriculum-based words). Read More

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http://dx.doi.org/10.1080/02699052.2019.1567939DOI Listing
January 2019
1 Read

Long-term factor structure of the Rivermead Post-Concussion Symptom Questionnaire in mild traumatic brain injury and normative sample.

Brain Inj 2019 30;33(5):618-622. Epub 2019 Jan 30.

b National Institute for Stroke and Applied Neuroscience, School of Public health & Psychosocial Studies , Auckland University of Technology , Auckland , New Zealand.

Background: Previous studies of the Rivermead Post-Concussive Questionnaire(RPQ)'s factor structure were conducted within 1 year post-injury. Post-concussive symptoms may persist, and are common in the general population, so determining if the factor structure in mild-TBI and controls differ is important. This study examined factor structure of the RPQ in adults 4 years post-mild-TBI and in age-/gender-matched controls. Read More

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http://dx.doi.org/10.1080/02699052.2019.1570339DOI Listing
January 2019
2 Reads

Opioids and cerebral physiology in the acute management of traumatic brain injury: a systematic review.

Brain Inj 2019 29;33(5):559-566. Epub 2019 Jan 29.

a Parkwood Institute Research , Lawson Health Research Institute,Parkwood Institute , London , Ontario , Canada.

Background: Following traumatic brain injury (TBI), optimization of cerebral physiology is recommended to promote more favourable patient outcomes. Accompanying pain and agitation are commonly treated with sedative and analgesic agents, such as opioids. However, the impact of opioids on certain aspects of cerebral physiology is not well established. Read More

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http://dx.doi.org/10.1080/02699052.2019.1574328DOI Listing
January 2019
1 Read

Agitated behavior scale in pediatric traumatic brain injury.

Brain Inj 2019 Jan 29:1-6. Epub 2019 Jan 29.

f Department of Critical Care Medicine , Hospital for Sick Children , Toronto , ON , Canada.

Agitation following TBI commonly occurs during the acute recovery phase. The ABS is a valid measure of agitation in adults following TBI. The objective of the study was to determine if ABS scores accurately measure acute agitation in pediatric patients recovering from TBI. Read More

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http://dx.doi.org/10.1080/02699052.2019.1565893DOI Listing
January 2019

Overview of pharmacological interventions after traumatic brain injuries: impact on selected outcomes.

Brain Inj 2019 29;33(4):442-455. Epub 2019 Jan 29.

l Department of Physical Medicine and Rehabilitation , University of Colorado Anschutz Medical Campus , Aurora , Colorado , USA.

The purpose of this study was to conduct an overview of systematic reviews (SRs) to appraise the published evidence related to pharmacological interventions after traumatic brain injury (TBI). Searches were conducted with Medline, Embase, PsycINFO, Web of Science, PubMed. 780 retrieved SRs underwent a two-level screening to determine inclusion. Read More

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http://dx.doi.org/10.1080/02699052.2019.1565896DOI Listing
January 2019
1.861 Impact Factor

Screening questionnaires for substance abuse post brain injury: a review.

Brain Inj 2019 26;33(5):551-558. Epub 2019 Jan 26.

a Lawson Health Research Institute , London , ON , Canada.

Objective: To assess the psychometric properties of the available assessment questionnaires for substance abuse studied within a brain injury population.

Methods: A literature search was conducted on MEDLINE, PsycINFO, CINAHL, and Embase databases. Articles published in English from inception through March 2018 on the screening questionnaires used to identify substance abuse post brain injury were reviewed. Read More

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http://dx.doi.org/10.1080/02699052.2019.1567938DOI Listing
January 2019

Self-awareness following a traumatic brain injury in childhood: a developmental perspective.

Brain Inj 2019 25;33(5):633-642. Epub 2019 Jan 25.

b University of Warwick , Coventry.

Impaired self-awareness is a common consequence following a brain injury that affects engagement in rehabilitation and results in poor long term functional outcomes. Literature regarding self-awareness following a brain injury in childhood is lacking. The aim of this research study was to understand the self-awareness of deficits from a developmental perspective. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1566838DOI Listing
January 2019
11 Reads

Development of the family needs questionnaire - pediatric version [FNQ-P] - phase I.

Brain Inj 2019 24;33(5):623-632. Epub 2019 Jan 24.

a Bloorview Research Institute , Toronto , Ontario , Canada.

Objective: To adapt the well-validated 37-item adult Family Needs Questionnaire to make it suitable for families of children and youth with acquired brain injury (ABI).

Methods: Measurement construction employed a modified Delphi technique to identify the most relevant content items for the pediatric Family Needs Questionnaire (FNQ-P). The Delphi process involved a panel of 11 ABI-team clinicians and seven family caregivers of children/youth with an ABI and four rounds of anonymous voting on each item's importance. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1566836DOI Listing
January 2019
12 Reads

Care coordination experiences of people with traumatic brain injury and their family members in the 4-years after injury: a qualitative analysis.

Brain Inj 2019 23;33(5):574-583. Epub 2019 Jan 23.

a Department of Epidemiology and Preventive Medicine , Monash University , Melbourne , Australia.

Title: Care coordination experiences of people with traumatic brain injury and their family members 4-years after injury: A qualitative analysis.

Aim: To explore experiences of care coordination in the first 4-years after severe traumatic brain injury (TBI).

Methods: A qualitative study nested within a population-based longitudinal cohort study. Read More

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http://dx.doi.org/10.1080/02699052.2019.1566835DOI Listing
January 2019
3 Reads

The long-term effects of childhood traumatic brain injury on adulthood relationship quality.

Brain Inj 2019 21;33(5):649-656. Epub 2019 Jan 21.

b School of Psychological Sciences , University of Melbourne , Melbourne , Australia.

Primary Objective: To investigated the long-term effect of childhood Traumatic Brain Injury (TBI) on adulthood Relationship Quality (RQ), examining injury severity, age of injury, and markers of prefrontal cortex (PFC) functioning, apathy, disinhibition, and executive dysfunction.

Research Design: Longitudinal, between-subjects, cross-sectional design using retrospective and current data.

Methods And Procedures: Participants (N = 169; 61 mild TBI (mTBI); 65 moderate to severe TBI (MSTBI); 43 orthopaedic injury (OI); Injury age: 1-17 years; Testing age: 18-31 years) completed a structured interview regarding their injury, demographic characteristics and RQ, the National Adults Reading Test, and Frontal Systems Behaviour Scale. Read More

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http://dx.doi.org/10.1080/02699052.2019.1567936DOI Listing
January 2019
1 Read

Prediction of discharge destination after traumatic brain injury in children using the head abbreviated injury scale.

Brain Inj 2019 19;33(5):643-648. Epub 2019 Jan 19.

a Department of Neurosurgery , University of Minnesota , Minneapolis , Minnesota , USA.

Introduction: Traumatic brain injury (TBI) is a major public health problem, particularly in children. Prognostication of injury severity at the time of presentation is difficult. The Abbreviated Injury Scale (AIS) is a commonly used anatomical-based coding system created to classify and describe injury severity after initial presentation, once test results are able to better define the anatomical characteristics of the injury. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1566966DOI Listing
January 2019
10 Reads

Physiological and pathological covariates of persistent concussion-related fatigue: results from two regression methodologies.

Brain Inj 2019 20;33(4):463-479. Epub 2019 Jan 20.

a Rehabilitation Sciences Institute, Faculty of Medicine , University of Toronto , Canada , Ontario , Canada.

Background: Fatigue severity in persons with mild traumatic brain injury (mTBI) has received little research attention, despite its typically positively skewed nature. Investigation of covariates across a range of fatigue severity may provide insight into important contributors.

Objective: To assess the relative significance of a priori-hypothesized covariates of physiological and pathological (mental and physical) fatigue in persons with mTBI/concussion, applying ordinary least squares (OLS) and quantile regression (QR) approaches. Read More

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http://dx.doi.org/10.1080/02699052.2019.1566833DOI Listing
January 2019
2 Reads

Validation of the Chinese version of the Coma Recovery Scale-Revised (CRS-R).

Brain Inj 2019 19;33(4):529-533. Epub 2019 Jan 19.

a International Vegetative State and Consciousness Science Institute, Hangzhou Normal University , Hangzhou , Zhejiang , China.

Primary Objective: This study aims to validate the Chinese version of the Coma Recovery Scale-Revised (CRS-R).

Methods: One hundred sixty-nine patients were assessed with both the CRS-R and the Glasgow Coma Scale (GCS), diagnosed as being in unresponsive wakefulness syndrome (UWS, formerly known as vegetative state), minimally conscious state (MCS), or emergence from MCS (EMCS). A subgroup of 50 patients has been assessed twice by the same rater, within 24 h. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1566832DOI Listing
January 2019
13 Reads

Impaired ankle joint mechanics during running can be resolved in people with traumatic brain injury.

Brain Inj 2019 20;33(5):670-678. Epub 2019 Jan 20.

c La Trobe Sport and Exercise Medicine Research Centre , La Trobe University , Bundoora , Victoria , Australia.

Objectives: 1) To compare lower-limb joint mechanics during running for people with traumatic brain injury (TBI) to equivalent data obtained from a group of healthy controls (HCs); and 2) To determine if deficits identified in biomechanical variables during running for people with TBI responded to a six-month period of rehabilitation.

Methods: Running biomechanics data were recorded from 12 people with TBI who were attending a large metropolitan rehabilitation hospital for mobility limitations, and a comparative sample of 10 HCs at baseline and six-month follow-up.

Main Measures: Average power absorbed and generated at the hip, knee and ankle joints during stance. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1567940DOI Listing
January 2019
9 Reads

Predictive utility of an adapted Marshall head CT classification scheme after traumatic brain injury.

Brain Inj 2019 19;33(5):610-617. Epub 2019 Jan 19.

i Department of Physical Medicine and Rehabilitation , Spaulding Rehabilitation Hospital , Charlestown , Massachusetts , USA.

Objective: To study the predictive relationship among persons with traumatic brain injury (TBI) between an objective indicator of injury severity (the adapted Marshall computed tomography [CT] classification scheme) and clinical indicators of injury severity in the acute phase, functional outcomes at inpatient rehabilitation discharge, and functional and participation outcomes at 1 year after injury, including death.

Participants: The sample involved 4895 individuals who received inpatient rehabilitation following acute hospitalization for TBI and were enrolled in the Traumatic Brain Injury Model Systems National Database between 1989 and 2014.

Design: Head CT variables for each person were fit into adapted Marshall CT classification categories I through IV. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1566970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436993PMC
January 2019
6 Reads

Psychometric evaluation of the Self-Awareness in Daily Life-3 Scale (SADL-3) for the assessment of self-awareness after acquired brain injury.

Brain Inj 2019 19;33(5):598-609. Epub 2019 Jan 19.

b Limburg Brain Injury Center , Maastricht University , Maastricht , The Netherlands.

Objective: The Self-Awareness in Daily Life-3 Scale (SADL-3) was designed to assess self-awareness in the chronic phase after acquired brain injury (ABI). The main objective was to evaluate its feasibility and usability for clinical practice, reliability and validity.

Methods: Participants were 89 patients with ABI. Read More

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http://dx.doi.org/10.1080/02699052.2019.1566969DOI Listing
January 2019
1 Read

Comparison of early and late depression after TBI; (the SHEFBIT study).

Brain Inj 2019 19;33(5):584-591. Epub 2019 Jan 19.

c Institute of Work Psychology , Sheffield University Management School , Sheffield , UK.

Objective: Evaluate the prevalence and risk factors for depression at 1 year after traumatic brain injury (TBI) and contrast against those at 10 weeks.

Methods: Prospective TBI admissions over 2 years to an emergency department were recruited to form a representative TBI population. Depression was recorded at 10 weeks and 1 year by HADS (Hospital Anxiety and Depression Scale) with score>8. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1566837DOI Listing
January 2019
15 Reads

Experiences of challenges and support among family members of people with acquired brain injury: a qualitative study in the UK.

Brain Inj 2019 19;33(4):401-411. Epub 2019 Jan 19.

a Head First , Kent , UK.

Primary Objective: Family members (FM) are affected by the impact of an Acquired Brain Injury (ABI) upon their relatives and play an important role in rehabilitation and long-term support. This study explores how families are affected and integrates their views on the formal/informal support received as a consequence of ABI.

Research Design: A qualitative research design was employed to capture the lived experience of FM of people with ABI. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1566967DOI Listing
January 2019
17 Reads

International survey on diagnostic and prognostic procedures in pediatric disorders of consciousness.

Brain Inj 2019 19;33(4):517-528. Epub 2019 Jan 19.

h DOC Research Laboratory and Neurorehabilitation Unit for DOC patients , Maugeri Clinical Scientific Institutes, IRCCS , Telese Terme , Italy.

Aims: 1. to investigate diagnostic and prognostic procedures routinely used by international professionals to assess children with disorders of consciousness (DoC); 2. to explore use and availability of internal and national guidelines for pediatric DoC; 3. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1565899DOI Listing
January 2019
11 Reads

Sex-dependent and chronic alterations in behavior and mitochondrial function in a rat model of pediatric mild traumatic brain injury.

Brain Inj 2019 19;33(4):534-542. Epub 2019 Jan 19.

b Alberta Children's Hospital Research Institute , University of Calgary , Calgary , Alberta , Canada.

Objective: To determine if chronic changes in mitochondrial function occur following a mild traumatic brain injury in young rats.

Research Design: Closed-head, weight drop model was used to cause mTBI by applying rotational forces to the brain without surgery. Behavioral battery was used to assess multiple dimensions of impairment across time. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1565898DOI Listing
January 2019
11 Reads

The effect of impact location on brain strain.

Brain Inj 2019 19;33(4):427-434. Epub 2019 Jan 19.

a Department of Mechanical Engineering , Technological University Dublin , Tallaght, Dublin , Ireland.

Objective: To determine the effect of impact direction on strains within the brain.

Research Design: Laboratory drop tests of hybrid III head-form and finite element simulation of impacts.

Methods And Procedures: A head-form instrumented with accelerometers and gyroscopes was dropped from 10 different heights in four orientations: front, rear, left and right-hand side. Read More

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http://dx.doi.org/10.1080/02699052.2019.1566834DOI Listing
January 2019
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Balance in chronic traumatic brain injury: correlations between clinical measures and a self-report measure.

Brain Inj 2019 14;33(4):435-441. Epub 2019 Jan 14.

b Research Department , Craig Hospital , Englewood , CO , USA.

Objective: To assess associations among commonly used self-report and clinical measures of balance in chronic TBI.

Design: Cross-sectional analysis of balance in a convenience sample of individuals at least one year post TBI.

Main Outcome Measures: Activities-Specific Balance Confidence Scale (ABC) (self-reported balance impairment), Community Balance and Mobility Scale (CB&M) (clinical measure validated in TBI), and Balance Evaluation Systems Test (BESTest) (clinical measure not validated in TBI). Read More

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http://dx.doi.org/10.1080/02699052.2019.1565900DOI Listing
January 2019
2 Reads

Bilateral M1 anodal transcranial direct current stimulation in post traumatic chronic minimally conscious state: a pilot EEG-tDCS study.

Brain Inj 2019 11;33(4):490-495. Epub 2019 Jan 11.

a Neuroscience and Rehabilitation Department , Ferrara University Hospital , Ferrara , Italy.

Objective: We tested the preliminary effects of bilateral anodal transcranial direct current stimulation (tDCS) in patients with disorders of consciousness.

Design: Open label pilot study.

Subjects: Ten chronic (greater than 12 months) patients in a minimally conscious state (MCS) following severe traumatic brain injury. Read More

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http://dx.doi.org/10.1080/02699052.2019.1565894DOI Listing
January 2019
2 Reads

Predictors of post-concussion symptom severity in a university-based concussion clinic.

Brain Inj 2019 9;33(4):480-489. Epub 2019 Jan 9.

c Department of Community Health and Family Medicine , University of Florida , Gainesville , FL , USA.

Objective: To investigate potential predictors of acute post-concussion symptom severity in a university population.

Methods: Data were obtained from the University of Florida Student Health Care Center Concussion Databank. Symptom severity, measured by the Sport Concussion Assessment Tool - third edition Symptom Evaluation (S3SE), was analyzed at 0-3 (n = 99) and 7-14 days (n = 56) post-concussion. Read More

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http://dx.doi.org/10.1080/02699052.2019.1565897DOI Listing
January 2019
2 Reads

Traumatic brain injury in patients screened for blood alcohol concentration based on the mechanism of injury.

Brain Inj 2019 5;33(4):419-426. Epub 2019 Jan 5.

f Department of Surgery, Trauma Surgery , Hamad General Hospital , Doha , Qatar.

Introduction: We aimed to investigate in-hospital outcomes of traumatic brain injury (TBI) based on blood alcohol concentration (BAC) and mechanism of injury (MOI).

Methods: We conducted a retrospective study for patients admitted with TBI between 2010 and 2014. Based on BAC, patients were classified into [negative (-BAC) and positive (+BAC) group]. Read More

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http://dx.doi.org/10.1080/02699052.2018.1553065DOI Listing
January 2019
5 Reads
1.861 Impact Factor

The relation between cognitive dysfunction and diffusion tensor imaging parameters in traumatic brain injury.

Brain Inj 2019 19;33(3):355-363. Epub 2018 Dec 19.

c Department of Radiology , Wayne State University School of Medicine , Detroit , MI , USA.

Purpose Of The Study: To investigate the association among global and regional white matter fractional anisotropy (FA) values following traumatic brain injury (TBI) and cognitive functioning.

Materials And Methods: This research was conducted in an urban rehabilitation hospital. Participants included adults who were healthy controls (n = 18) or who had a TBI (n = 27). Read More

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http://dx.doi.org/10.1080/02699052.2018.1553073DOI Listing
December 2018
2 Reads
1.861 Impact Factor

Targeting mast cell as a neuroprotective strategy.

Brain Inj 2018 Dec 17:1-11. Epub 2018 Dec 17.

a Department of Basic Sciences, Division of Physiology , Loma Linda University School of Medicine , Loma Linda , CA , USA.

Background: Mast cells (MCs) are perivascularly located immune cells of haematopoietic origin. Emerging evidences suggest that the activation of MCs play important roles in the pathogenesis of blood brain barrier disruption, neuroinflammation, and neurodegeneration.

Objectives: In this review, we aimed to discuss the detrimental effects of MCs in response to various types of brain injury, as well as the therapeutic potential and neuroprotective effects of targeting the activation and degranulation of MCs, particularly in the management of the acute phase. Read More

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https://www.tandfonline.com/doi/full/10.1080/02699052.2018.1
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http://dx.doi.org/10.1080/02699052.2018.1556807DOI Listing
December 2018
23 Reads