Biomed Res Int 2017 19;2017:4790810. Epub 2017 Sep 19.
Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Chronic pruritus is a difficult condition to treat and is associated with several comorbidities, including insomnia, depression, and decreased quality of life. Treatment for chronic itch includes corticosteroids, antihistamines, and systemic therapies such as naltrexone, gabapentin, UV light therapy, and immunomodulatory treatments, including azathioprine, methotrexate, and cellcept. However, some patients still remain refractory to conventional therapy. Read More