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J Clin Neuromuscul Dis 2022 Jun;23(4):229-230

Mercy Medical Center, Baltimore, MD.

J Clin Neuromuscul Dis 2022 Jun;23(4):227-228

Department of Radiology, Hospital for Special Surgery, New York, NY.

Surg Neurol Int 2022 15;13:152. Epub 2022 Apr 15.

Departments of Neurosurgery, Brigham and Women's Hospital, Boston, Massachusetts, United States.

Background: Parsonage-Turner syndrome (PTS) is a rare brachial plexopathy characterized by self-limiting shoulder girdle and upper arm pain followed by the upper extremity weakness and sensory changes. While the etiology is not well-understood, the most common cause of PTS is thought to be postviral. There are at least nine reports, to the best of our knowledge, of PTS associated with COVID-19 infection and nine reports associated with COVID-19 vaccination. Read More

Children (Basel) 2022 Apr 7;9(4). Epub 2022 Apr 7.

Department of Rehabilitation Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu 42601, Korea.

Hereditary neuropathy with liability to pressure palsy (HNPP) makes nerves increasingly susceptible to mechanical pressure at entrapment sites. Neuralgic amyotrophy (NA) can cause sudden regional weakness following events to which the patient is immunologically predisposed, such as vaccination. However, NA related to human papilloma virus (HPV) vaccination is seldom reported. Read More

Hong Kong Med J 2022 Apr 8;28(2):178-180. Epub 2022 Apr 8.

Department of Anaesthesia, Pamela Youde Nethersole Eastern Hospital, Hong Kong.

CMAJ 2022 Apr;194(13):E502-E503

Deputy editor, CMAJ.

CMAJ 2022 Apr;194(13):E495-E499

Departments of Physical Medicine and Rehabilitation (Miller, Hooper) and Internal Medicine (Sharma), Faculty of Medicine, University of Manitoba, Winnipeg, Man.

Zhonghua Liu Xing Bing Xue Za Zhi 2022 Mar;43(3):431-435

School of Public Health, Peking University, Beijing 100191, China Research Center of Clinical Epidemiololgy, Peking University Third Hospital, Beijing 100191, China.

To establish a sustainable updated literature data warehouse for global vaccine safety assessment, and provide data support for evidence-based vaccine safety assessment. Semi-automated construction and updating of a literature data warehouse were achieved through the continuous integration of standard operating steps of evidence-based reviews with artificial intelligence technologies. Following the standard procedure of a systematic literature review, the literatures about vaccine safety assessment published before November 29, 2020 were retrieved from 9 databases including OVID, Scopus, Web of Science, Cochrane Library, and ClinicalTrails. Read More

BMC Neurol 2022 Mar 16;22(1):96. Epub 2022 Mar 16.

Department of Gerontology, Neuroscience and Orthopedics, Fondazione Universitaria Policlinico Gemelli, IRCCS, Rome, Italy.

Background: Neurological manifestations of Sars-CoV-2 infection have been described since March 2020 and include both central and peripheral nervous system manifestations. Neurological symptoms, such as headache or persistent loss of smell and taste, have also been documented in COVID-19 long-haulers. Moreover, long lasting fatigue, mild cognitive impairment and sleep disorders appear to be frequent long term neurological manifestations after hospitalization due to COVID-19. Read More

Neurol Sci 2022 Jun 15;43(6):3515-3517. Epub 2022 Mar 15.

Department of Neurology, Asl To4 Ivrea, P.zza Credenza, 2-10015, Ivrea, Turin, Italy.

Adv Biomed Res 2022 31;11. Epub 2022 Jan 31.

Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Parsonage-Turner syndrome (PTS) is a rare syndrome of unknown etiology; however, it is believed that an abnormality of immune response after a previous infection may be the cause of the disease. We report neuralgic amyotrophy in a patient with a history of kidney transplantation with severe acute respiratory distress syndrome coronavirus 2 infection. This literature is reviewed regarding clinical presentation, etiology, treatment, and prognosis of PTS after COVID-19 infection. Read More

Lupus 2022 Apr 8;31(4):500-504. Epub 2022 Mar 8.

Department of Medicine, State University of New York, 12302Upstate Medical University, Syracuse, NY, USA.

Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects many organs of the body including the peripheral nervous system (PNS) which has potential significant impact. Plexopathy is rare but one of the serious PNS manifestations of lupus.

Case: A 41-year-old female presented with recurrent attacks of painful brachial plexopathy and right hemi-diaphragmatic paralysis. Read More

Zh Nevrol Psikhiatr Im S S Korsakova 2022 ;122(1):8-14

Burnazyan Medical and Biological University of Innovation and Continuing Education Federal Medical Biophysical Center Federal Medical and Biological Agency of Russia, Moscow, Russia.

A review of the literature covering the issues of etiology, pathogenesis, variety of atypical forms, diagnosis and management of patients with neuralgic amyotrophy is presented. Read More

Neurology 2022 04 10;98(14):597-600. Epub 2022 Feb 10.

From the Departments of Neurology (A.D., G.T., T.R.M., O.S.) Infectious Diseases (E.C.-B.), Inselspital, Bern University Hospital, University of Bern, Switzerland.

We present a case of a cat owner with a scar on his right thenar eminence, followed by lymphadenopathy in the right axilla, general malaise and fever, and subsequent onset of bilateral neuralgic amyotrophy within one week. After a comprehensive workup, cat scratch disease caused by was confirmed serologically and adequately treated. Despite antibiotic treatment, the patient presented clinically with persistent bilateral, asymmetric neuropathy of the median nerve, predominantly the interosseous anterior nerve, which was confirmed by multifocal swelling and hyperintense signal of the nerves on T2-weighted MR neurography. Read More

Clin Neuropathol 2022 May-Jun;41(3):135-144

Neuralgic amyotrophy (NA), also known as Parsonage-Turner syndrome (PTS), is a distinct idiopathic immune-mediated neuritis of the brachial plexus, characterized by sudden attacks of severe neuropathic pain usually in the shoulder and/or arm, followed by progressive neurologic deficits, including weakness, atrophy, and occasionally sensory abnormalities. Pathogenesis is assumed to be multifactorial, and several observations support the hypothesis of an immune-triggering event preceding PTS, most frequently infections. A literature review reveals a variety of clinical presentations and courses. Read More

Neurol Sci 2022 Mar 29;43(3):1685-1693. Epub 2022 Jan 29.

Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, Sichuan Province, China.

As the incidence of peripheral neurological diseases increases, the precise display of nerves becomes important in imaging examinations. Among them, the pain caused by brachial plexus neuropathy is very prominent, and the magnetic resonance imaging of nerve is quite complex and messy. This paper will systematically elaborate from the aspects of brachial plexus neuropathy, morphological and functional imaging, and post-processing. Read More

Surg Radiol Anat 2022 Feb 23;44(2):223-226. Epub 2022 Jan 23.

Department of Anatomy, University of Lyon 1, 8 Avenue Rockefeller, 69003, Lyon, France.

Purpose: The main anatomic variations should be taught along with the classical anatomy curriculum, since they can mislead both diagnosis and treatment. We report here a clinical and radiological case of left C6 cervicobrachial neuralgia recurrence due to a vertebral artery loop, we then describe 13 published cases of such neurovascular conflicts.

Case: A 51-year-old woman suffered from recurrence of C6 cervicobrachial neuralgia after an initial C5-C6 decompression-fusion. Read More

JBJS Case Connect 2022 01 12;12(1). Epub 2022 Jan 12.

Ann Indian Acad Neurol 2021 Sep-Oct;24(5):693-702. Epub 2021 May 28.

Department of Neurology, Deenanath Mangeshkar Hospital and Research Center, Pune, Maharashtra, India.

Background: Dengue is a common endemic infection in India. Neurological complications involving various parts of the neuro-axis have been reported. We report neurological complications amongst dengue patients admitted to a tertiary hospital in Western India. Read More

Rev Neurol (Paris) 2022 Jan-Feb;178(1-2):157-158. Epub 2021 Dec 23.

Centre de Référence des Maladies Neuromusculaires AOC, FILNEMUS, Euro-NMD, Hôtel-Dieu, CHU Nantes, 44093 Nantes, France.

JBJS Case Connect 2021 12 22;11(4). Epub 2021 Dec 22.

Department of Orthopedic Surgery, Beaumont Dearborn Hospital, Dearborn, Michigan.

Case: A 43-year-old man developed Parsonage-Turner syndrome shortly after receiving a COVID-19 vaccine. The patient presented to the hospital 5 days after receiving a COVID-19 vaccine to the right shoulder complaining of severe right shoulder pain, right upper extremity swelling, and weakness. Clinical examination, physical examination, and magnetic resonance imaging findings were consistent with Parsonage-Turner syndrome. Read More

JSES Rev Rep Tech 2021 Aug 21;1(3):252-256. Epub 2021 Apr 21.

Department of Radiology, Clínica Cordillera, Santiago, Chile.

J Med Case Rep 2021 Dec 13;15(1):589. Epub 2021 Dec 13.

Department of Health Sciences, University of Genoa, L.go R. Benzi, 10 (Building 3), 16122, Genoa, Italy.

Background: Parsonage-Turner syndrome is an acute peripheral neuropathy that affects the upper brachial plexus region. Previously published reports demonstrate that the condition can be triggered by surgery, infection, autoimmune diseases, strenuous exercise, trauma, radiation, and vaccination. Parsonage-Turner syndrome has already been reported in three other patients who were vaccinated against coronavirus disease 2019. Read More

J Int Med Res 2021 Nov;49(11):3000605211056783

Department of Rehabilitation Medicine, 37976Keimyung University School of Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea.

The ongoing global administration of vaccines for coronavirus disease 2019 (COVID-19) means that increasing numbers of patients are likely to present with post-vaccination complications. We describe the first reported case of neuralgic amyotrophy (NA) involving the lumbosacral plexus occurring after AstraZeneca COVID-19 vaccination. The patient presented with acute-onset leg paralysis following administration of the vaccine. Read More

J Am Coll Radiol 2021 11;18(11S):S423-S441

Specialty Chair, Atlanta VA Health Care System and Emory University, Atlanta, Georgia.

Plexopathy may be caused by diverse pathologies, including trauma, nerve entrapment, neoplasm, inflammation, infection, autoimmune disease, hereditary disease, and idiopathic etiologies. For patients presenting with brachial or lumbosacral plexopathy, dedicated plexus MRI is the most appropriate initial imaging modality for all clinical scenarios and can identify processes both intrinsic and extrinsic to the nerves. Other imaging tests may be appropriate for initial imaging depending on the clinical scenario. Read More

J Clin Med 2021 Nov 5;10(21). Epub 2021 Nov 5.

Physiotherapy and Pain Research Center, General Foundation of the University of Alcalá, 28805 Madrid, Spain.

Background: This study aimed to compare the effectiveness of cervical lateral glide (CLG) added to median nerve neural mobilization (MNNM) in patients with neck pain (NP).

Methods: A single-blinded randomized controlled clinical trial was carried out in a Pain Management Unit from a Hospital. A total sample of 72 patients with NP was recruited from a hospital. Read More

JBJS Case Connect 2021 09 24;11(3). Epub 2021 Sep 24.

Department of Orthopaedic Surgery and Rehabilitation, The University of Texas Medical Branch, Galveston, Texas.

Case: Parsonage-Turner syndrome, also known as brachial neuritis or neuralgic amyotrophy, is characterized by sudden-onset pain and subsequent weakness of the shoulder. Known precipitating factors include viral and bacterial infections and certain immunizations. Isolated cases after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been reported. Read More

Muscle Nerve 2021 12 14;64(6):E27-E28. Epub 2021 Oct 14.

Neurological Institute, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.

Radiol Case Rep 2021 Nov 26;16(11):3176-3181. Epub 2021 Aug 26.

Centro de Diagnóstico Por Imágenes Clínico Integral (CEDICLIN), Santiago, Dominican Republic.

Parsonage-Turner Syndrome (PTS), also known as brachial neuritis or neuralgic amyotrophy, is a rare disorder affecting 2 to 3 individuals per 100,000 each year. Abrupt onset shoulder pain, followed by motor weakness, paresthesia and hypoesthesia, is usually reported, lasting several months with variable recovery. The etiology of the disease may be idiopathic or triggered by an underlying autoimmune disease in genetically susceptible individuals. Read More

Yonsei Med J 2021 Sep;62(9):868-871

Division of Infectious Disease, Department of Internal Medicine, Myongji Hospital, Goyang, Korea.

Parsonage-Turner syndrome is a rare neurological disease of varying etiology characterized by severe shoulder pain, muscle weakness, and atrophy. Mechanisms are unclear, but are thought to be genetic and immune-mediated reactions. Rarely, Parsonage-Turner syndrome occurs as a side effect of vaccination. Read More