324 results match your criteria Bowenoid Papulosis

Two Cases of Multiple Epidermolytic Acanthomas Mimicking Verruca Vulgaris.

Ann Dermatol 2020 Dec 11;32(6):512-515. Epub 2020 Nov 11.

Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Epidermolytic acanthoma (EA) is a rare benign tumor, which usually appears as a solitary small papule. However, there are a few case reports of multiple EA, most of which occurs on the genital area. Cases of multiple EA may mimic verruca vulgaris, condyloma accuminatum, seborrheic keratosis, and bowenoid papulosis, and therefore, can be easily misdiagnosed. Read More

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December 2020

A case of perianal bowenoid papulosis: dermoscopic features and a review of previous cases.

Acta Dermatovenerol Alp Pannonica Adriat 2021 Mar;30(1):39-41

Department of Dermatology and Venereology, Faculty of Medicine, Trakya University, Edirne, Turkey.

Bowenoid papulosis is an uncommon precancerous condition of the genitalia caused by oncogenic human papillomavirus types. It is seen in young, sexually active adults and histologically resembles Bowen's disease. Dermoscopy is useful in the diagnosis of both pigmented and non-pigmented skin lesions, but dermoscopic diagnostic accuracy criteria have not yet developed in diseases such as bowenoid papulosis and Bowen's disease. Read More

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Genital premalignant and malignant diseases: a retrospective study of male genital skin biopsies.

Int J Dermatol 2021 Jun 27;60(6):712-716. Epub 2021 Feb 27.

Mater Misericordiae Hospital, Brisbane, Queensland, Australia.

Background: Genital skin malignancies are a rare entity encountered by clinicians that may result in significant morbidity and mortality. Lack of familiarity or expertise in this area among clinicians can delay appropriate management of these conditions and may result in disease progression.

Methods: We performed a retrospective descriptive cohort study of male patients who received a genital skin biopsy reported by one major dermatopathology laboratory between January 2017 and December 2018 with a histological diagnosis of a premalignant or malignant condition. Read More

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The prevalence of human leucocyte antigen and human papillomavirus DNA in penile intraepithelial neoplasia in England 2011-2012.

Int J STD AIDS 2021 Apr 12;32(5):388-395. Epub 2021 Feb 12.

Dermatology Department, University College Hospital, Chelsea and Westminster Hospital, London, UK.

Background: The pathogenesis of penile intraepithelial neoplasia (PeIN) is unclear but human papillomavirus (HPV) infection and polymorphisms in human leucocyte antigen (HLA).

Objectives: To examine the prevalence of HPV DNA and HLA in PeIN.

Methods: Adult Caucasian men with a clinical and histological diagnosis of PeIN, that is, Bowenoid papulosis (BP), Bowen's disease of penis (BDP) and erythroplasia of Queyrat (EQ) were selected and phenotyped from the clinical records. Read More

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[Update on precursors of vulvar carcinoma].

Gynecol Obstet Fertil Senol 2021 Jun 6;49(6):538-546. Epub 2020 Nov 6.

Institut Curie Saint-Cloud, 35, rue Dailly, 92210 Saint-Cloud, France; Université de Versailles-Saint-Quentin-en-Yvelines, UFR sciences de la santé, Versailles, France. Electronic address:

Vulvar carcinomas represent 4% of all gynaecological cancers with 838 new cases in France in 2018. The precursor lesions of vulvar carcinomas are differentiated vulvar intraepithelial lesion (dVIN) in a context of lichen sclerosus and vulvar high-grade squamous intraepithelial lesion (HSIL) link to human papillomavirus (HPV) infection. Three typical clinical forms of HSIL are described: the Bowenoid papulosis, the Bowen's disease and the confluent VIN. Read More

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Dihydroartemisinin administration improves the effectiveness of 5-aminolevulinic acid-mediated photodynamic therapy for the treatment of high-risk human papillomavirus infection.

Photodiagnosis Photodyn Ther 2021 Mar 4;33:102078. Epub 2020 Nov 4.

Molecular Diagnosis and Treatment Center for Infectious Diseases, Dermatology Hospital, Southern Medical University, Guangzhou 510091, China.

Aims And Background: High-risk human papillomavirus (HR-HPV) infection has been confirmed to be highly related to diseases such as Bowenoid papulosis, cervical cancer, and cervical intraepithelial neoplasia. 5-aminolevulinic acid-mediated PDT (ALA-PDT) has been used in a variety of HR-HPV infection-related diseases. Dihydroartemisinin (DHA) is one of artemisinin derivatives, and has inhibitory effects on a variety of cancer cells. Read More

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Challenge of reflectance confocal microscopy in the diagnosis of genital warts.

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2020 Aug;45(8):988-993

Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410043, China.

Objectives: Reflection confocal microscopy (RCM) is commonly used to assist in the diagnosis of skin diseases. RCM has been found to be useful in the diagnosis of genital warts. The characteristics of genital warts under RCM are not specific. Read More

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The management of penile intraepithelial neoplasia (PeIN): clinical and histological features and treatment of 345 patients and a review of the literature.

J Dermatolog Treat 2020 Aug 6:1-16. Epub 2020 Aug 6.

Department of Dermatology, University College London Hospitals, London, UK.

Introduction: Penile intraepithelial neoplasia (PeIN) is a histological term for precancerous penile lesions. PeIN is important due to the high morbidity and mortality associated with progression to penile squamous cell carcinoma (PSSC). But PeIN is rare, contributing to a limited evidence-base for the relative efficacy of available treatment options. Read More

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Reflectance Confocal Microscopy of Pigmented Bowen's Disease: A Case Series of Difficult to Diagnose Lesions.

Case Rep Dermatol 2020 May-Aug;12(2):98-106. Epub 2020 May 15.

Department of Medicine and Medical Specialties, University of Alcalá, Madrid, Spain.

Pigmented Bowen's disease is a rare variant of in situ squamous skin cell carcinoma. It mainly affects patients between 60 and 70 years of age. Its clinical features include well-demarcated, pigmented plaque arising in photo-exposed areas of the body. Read More

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A case of bowenoid papulosis treated with sequential curettage and photodynamic therapy.

Photodermatol Photoimmunol Photomed 2020 05 27;36(3):251-253. Epub 2020 Feb 27.

Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.

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squamous cell carcinoma of male and female external genitalia.

Indian J Sex Transm Dis AIDS 2019 Jul-Dec;40(2):168-171

Department of Dermatology, Topiwala National Medical College and BYL Nair Hospital, Mumbai, Maharashtra, India.

squamous cell carcinoma (SCC) of male and female genitalia can present as Bowen's disease (BD), erythroplasia of Queyrat, Bowenoid papulosis, Paget's disease, pseudoepitheliomatous keratotic, and micaceous balanitis. BD is SCC . It affects both skin and mucous membranes and has the potential to progress to invasive SCC. Read More

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January 2020

Premalignant male genital dermatoses.

Indian J Sex Transm Dis AIDS 2019 Jul-Dec;40(2):97-104

Department of Skin and VD, Shree Krishna Hospital, Karamsad, Gujarat, India.

The spectrum of conditions affecting the penile skin is varied and ranges from simple, benign dermatoses to premalignant and malignant conditions. Anogenital malignancies and premalignancies are an important personal/public health problem due to their effects on individuals' physical, mental, and sexual health. Furthermore, due to their etiological association with human papillomavirus infection, anogenital malignancies, and premalignancies constitute an immense public health burden. Read More

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January 2020

Therapeutic evaluation of 5-aminolevulinic acid-mediated photodynamic therapy in Bowenoid papulosis.

Photodiagnosis Photodyn Ther 2020 Mar 20;29:101635. Epub 2019 Dec 20.

Department of Dermatology and Venereology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address:

Background: Bowenoid papulosis is a polymorphic papular disease that occurs on the external genital area. We investigated the efficacy of 5-aminolevulinic acid-mediated photodynamic therapyin the treatment of Bowenoid papulosis.

Methods: We investigated 200 Bowenoid papulosis cases from the Department of Dermatology and Venereology of Nanfang Hospital in 2016-2018. Read More

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Efficacy and Tolerability of Topical Polyphenon E in Multiple "Seborrheic Keratosis-Like" Lesions of the Groin in an Immunocompetent 26-Year-Old Man.

Case Rep Dermatol 2019 Sep-Dec;11(3):310-316. Epub 2019 Nov 7.

Medical Department Cantabria Labs Difa Cooper, Caronno Pertusella, Italy.

Polyphenon E 10%, a green tea extract containing epigallocatechin gallate (EGCG) as the main active compound, is a topical formulation indicated for the treatment of genital warts. Polyphenon E has also shown to be very effective in the treatment of periungual and plane warts. Here, we report a dramatic clinical effect of topical treatment with polyphenon E in a subject with multiple "seborrheic keratosis-like" lesions of the genital area. Read More

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November 2019

Distinguishing bowenoid papulosis from Bowen disease in the mouth: A case report.

J Cutan Pathol 2020 Mar 30;47(3):257-262. Epub 2019 Sep 30.

Department of Oral Medicine (Oral Pathology), Dental School, Federal University of Goiás, Goiânia, Brazil.

Bowenoid papulosis (BPap) is an uncommon skin disorder linked to human papillomavirus (HPV) infection and characterized clinically by the presence of scattered papules or small plaques, multiple and pigmented, that involve the stratified squamous epithelium. Bowen disease (BD) is recognized as the main differential diagnosis of BPap. An 80-year old white woman was referred for the evaluation of multiple, brown verrucous papules measuring 3 to 4 mm in diameter on the right maxillary gingiva. Read More

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Linear Bowenoid Papulosis.

Actas Dermosifiliogr (Engl Ed) 2020 Jan 25;111(1):76-77. Epub 2019 Sep 25.

Servicio de Dermatología, Hospital do Meixoeiro, EOXI, Vigo, Pontevedra, España.

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January 2020

Human Papilloma Virus Infection and Anal Squamous Intraepithelial Lesions.

Clin Colon Rectal Surg 2019 Sep 22;32(5):347-357. Epub 2019 Aug 22.

Department of Surgery, Centro de Educación Médica e Investigaciones clínicas, Buenos Aires, Argentina.

This article addresses the natural history of the human papilloma virus (HPV) infection to anal squamous intraepithelial lesions, and onto squamous cell carcinoma of the anus. This article provides overviews of the virology, pathophysiology, nomenclature, classification, historical terms, risk factors, clinical evaluation, differential diagnosis, and treatment of HPV infection and its sequelae. Read More

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September 2019

Bowenoid papulosis unveiling a rare cause of immunosuppression.

Int J STD AIDS 2019 04 4;30(5):522-525. Epub 2019 Feb 4.

Department of Dermatology & Venereology, Govt. Medical College, Thrissur, Kerala.

Bowenoid papulosis (BP) is a premalignant condition usually caused by oncogenic types of human papillomavirus (HPV) presenting clinically as warty genital papules. Adult T-cell leukaemia-lymphoma (ATLL) is a peripheral T-cell leukaemia-lymphoma caused by the retrovirus, human T-cell lymphotropic virus 1 (HTLV-1). We report a case of BP initially mistaken as genital warts; on detailed evaluation the patient had features of chronic immunosuppression. Read More

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Dermatoscopic findings of penile intraepithelial neoplasia: Bowenoid papulosis, Bowen disease and erythroplasia of Queyrat.

Australas J Dermatol 2019 Aug 25;60(3):e201-e207. Epub 2018 Dec 25.

Department of Dermatology, University College London Hospital, London, UK.

Background/objectives: The clinical diagnosis of penile intraepithelial neoplasia is challenging. No specific dermoscopic criteria for penile intraepithelial neoplasia have been described in the literature. This study aimed to describe and evaluate the dermoscopic features of penile intraepithelial neoplasia. Read More

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Human papillomavirus 34 associated with bowenoid papulosis of the penile shaft.

J Dermatol 2019 Jun 20;46(6):e192-e193. Epub 2018 Dec 20.

Department of Dermatology, Tokyo Women's Medical University Yachiyo Medical Center, Chiba, Japan.

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Oral bowenoid papulosis.

Cutis 2018 Nov;102(5):E27-E29

Division of Anatomic Pathology, Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA.

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November 2018

Penile intraepithelial neoplasia: Nomenclature, incidence and progression to malignancy in the Netherlands.

Int J Urol 2019 03 3;26(3):353-357. Epub 2018 Dec 3.

Department of Urology, University Medical Center Utrecht, Utrecht, the Netherlands.

Objective: To determine the incidence of penile intraepithelial neoplasia in the Netherlands using a nationwide histopathology registry and to discuss the nomenclature of premalignant penile lesions.

Methods: Data from patients in the Netherlands diagnosed with a premalignant penile lesion between January 1998 and December 2007 were collected from the nationwide histopathology registry (PALGA); this database covers all pathology reports of inhabitants in the Netherlands. The premalignant lesions included were erythroplasia of Queyrat; Bowen's disease; bowenoid papulosis; mild, moderate and severe dysplasia; and carcinoma in situ of the penis. Read More

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Epidermal mast cells in Bowenoid papulosis during topical imiquimod therapy.

J Dermatol 2019 Apr 11;46(4):e137-e138. Epub 2018 Sep 11.

Department of Dermatology, Fukushima Medical University, Fukushima, Japan.

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Verruciform and Condyloma-like Squamous Proliferations in the Anogenital Region.

May P Chan

Arch Pathol Lab Med 2019 07 11;143(7):821-831. Epub 2018 Sep 11.

From the Department of Pathology, University of Michigan Health System, Ann Arbor.

Context.—: Histologic distinction between condyloma acuminatum and various benign and malignant condyloma-like lesions in the anogenital area poses a common diagnostic challenge to pathologists across subspecialties.

Objective. Read More

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[Penile intra-epithelial neoplasia].

Prog Urol 2018 Sep 22;28(10):466-474. Epub 2018 Jun 22.

Service de dermatologie, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France.

Introduction: Penile intra-epithelial neoplasia (PIN) are precancerous lesions, characterized by architectural and cytological abnormalities of the genital epithelium, from which can arise squamous carcinomas.

Methods: A literature review was performed on the Medline database, considering the articles listed between October 2007 and October 2017 dealing with PIN, using the following keywords "intraepithelial neoplasia" or "Bowen's disease" or "erythroplasia of Queyrat" or "bowenoid papulosis" and "penis ». Papers were selected according to their language (English and French) and their relevance. Read More

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September 2018

Genital bowenoid papulosis: the variegated dermoscopic features.

G Ital Dermatol Venereol 2018 Aug;153(4):595-597

Unit of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, Policlinico Sant'Orsola-Malpighi, University of Bologna, Bologna, Italy.

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Combination of imiquimod with cryotherapy in the treatment of penile intraepithelial neoplasia.

JAAD Case Rep 2017 Nov 6;3(6):546-549. Epub 2017 Nov 6.

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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November 2017

Urologic Dermatology: a Review.

Curr Urol Rep 2017 Aug;18(8):62

Virginia Mason Medical Center, Seattle, WA, USA.

Purpose Of Review: Genital dermatology represents a challenge to many providers. Though dermatologic lesions involving the genitalia may present to any of a number of practices, ranging from primary care to urology, gynecology, and dermatology, few training programs provide significant training regarding the diagnosis and management of genital dermatologic lesions. The purpose of this review is to provide urologists with an overview of common genital dermatological lesions that may be encountered in a clinic. Read More

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Vulvar Bowenoid Papulosis: Histologically High-Grade Squamous Intraepithelial Lesion Known to Spontaneously Regress.

J Low Genit Tract Dis 2017 07;21(3):e30-e32

1Department of Pathology and Laboratory Medicine, Wexner Medical Center at The Ohio State University, Columbus, OH; and 2Department of Obstetrics and Gynecology, Wexner Medical Center at The Ohio State University, Columbus, OH.

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