10,218 results match your criteria Bowen Disease


Development and validation of a haematuria cancer risk score to identify patients at risk of harbouring cancer.

J Intern Med 2018 Dec 6. Epub 2018 Dec 6.

Division of Surgery & Interventional Science, University College London, London, UK.

Background: A lack of consensus exists among national guidelines regarding who should be investigated for haematuria. Type of haematuria and age specific thresholds are frequently used to guide referral for investigation of haematuria.

Objectives: To develop and externally validate the haematuria cancer risk score (HCRS) to improve patient selection for investigation of haematuria. Read More

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December 2018

Multimorbidity rehabilitation versus disease-specific rehabilitation in people with chronic diseases: a pilot randomized controlled trial.

Pilot Feasibility Stud 2018 29;4:181. Epub 2018 Nov 29.

1Department of Physiotherapy/Community Services, Western Health, 176 Furlong Road, St Albans, Victoria 3021 Australia.

Background: Multimorbidity (the co-existence of two or more chronic conditions in an individual) is a growing healthcare burden internationally; however, healthcare and disease management, including rehabilitation, is often delivered in single-disease siloes. The aims of this study were to (1) evaluate the safety and feasibility of multimorbidity rehabilitation compared to a disease-specific rehabilitation program in people with multimorbidity and (2) gather preliminary data regarding clinical outcomes and resource utilization to inform the design of future trials.

Methods: A pilot feasibility randomized controlled trial with concealed allocation, assessor blinding, and intention-to-treat analysis. Read More

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November 2018

Development and Validation of an Electronic Postoperative Morbidity Score.

Anesth Analg 2018 Nov 30. Epub 2018 Nov 30.

From the University Division of Anaesthesia.

Background: Electronic health records are being adopted due to numerous potential benefits. This requires the development of objective metrics to characterize morbidity, comparable to studies performed in centers without an electronic health record. We outline the development of an electronic version of the postoperative morbidity score for integration into our electronic health record. Read More

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November 2018

Clinico-pathological predictors of mismatch repair deficiency in sebaceous neoplasia: A large case series from a single Australian private pathology service.

Australas J Dermatol 2018 Dec 2. Epub 2018 Dec 2.

Department of Clinical Pathology, Colorectal Oncogenomics Group, The University of Melbourne, Parkville, Victoria, Australia.

Background/objectives: Loss of expression of mismatch repair (MMR) proteins is frequently observed in sebaceous skin lesions and can be a herald for Lynch syndrome. The aim of this study was to identify clinico-pathological predictors of MMR deficiency in sebaceous neoplasia that could aid dermatologists and pathologists in determining which sebaceous lesions should undergo MMR immunohistochemistry (IHC).

Methods: An audit of sebaceous skin lesions (excluding hyperplasia) where pathologist-initiated MMR IHC was performed between January 2009 to December 2016 was undertaken from a single pathology practice identifying 928 lesions from 882 individuals. Read More

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December 2018

Acral and Multicentric Pigmented Bowen's Disease in HIV-Positive Patients: Report on Two Unusual Cases.

Indian J Dermatol 2018 Nov-Dec;63(6):506-508

Centro De Investigación En Enfermedades Infecciosas, Instituto Nacional De Enfermedades Respiratorias, Ismael Cosío Villegas, México City, México.

squamous cell carcinoma of the skin (SCCis or Bowen's disease) is a common intraepidermal cutaneous malignancy with a low invasive potential. Acral Bowen's disease is usually solitary, but multiple acral SCCis have been reported. Pigmented Bowen's disease is typically unilesional and characterized by a hyperpigmented plaque with a velvety of keratotic surface, which can eventually simulate melanoma clinically. Read More

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December 2018

The history of suture anchors in orthopaedic surgery.

Clin Biomech (Bristol, Avon) 2018 Nov 23;61:70-78. Epub 2018 Nov 23.

Princess Alexandra Hospital, 199 Ipswich Rd, Woolloongabba, QLD 4102, Australia; Brisbane Hand and Upper Limb Research Institute, 259 Wickham Terrace, Spring Hill, QLD 4000, Australia; Field Orthopaedics Research Group, 375 Wickham Terrace, Spring Hill, QLD 4000, Australia.

The suture anchor allows secure fixation of soft tissue to bone and has become an invaluable tool for the orthopaedic surgeon. The original suture anchor was developed over 3 decades ago when a suture was bonded to a headless screw. Since then anchors have undergone a wide variety of design modifications to increase strength and allow for new applications based on biomechanical and clinical evidence. Read More

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November 2018

Actinic keratosis and squamous cell carcinoma of the elderly

Rev Prat 2017 12;67(10):1084-1088

Service de gériatrie - plaies et cicatrisation, hôpital Rothschild, Assistance publique-Hôpitaux de Paris, Paris, France.

Actinic keratosis and squamous cell carcinoma in the elderly. The increase in life expectancy and the change in the habits of the population with respect to UV exposure have led to an increase in the incidence of actinic keratosis (AK) and squamous cell carcinoma (SCC). There is no specific recommendation for the "frail" elderly, but they would not differ much from the recommendations of the younger subjects. Read More

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December 2017
3 Reads

Childhood health and education outcomes following early term induction for large-for-gestational age: a population-based record linkage study.

Acta Obstet Gynecol Scand 2018 Dec 4. Epub 2018 Dec 4.

Clinical and Population Perinatal Health Research, Kolling Institute, Northern Sydney Local Health District, Sydney, NSW, Australia.

Introduction: There is debate about optimal management of pregnancies with a large-for-gestational age baby. A recent randomized controlled trial reported that early term induction of labor reduced cesarean section rates and infant morbidity. However, long term childhood outcomes have not been assessed. Read More

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December 2018
1 Read

Double trouble in the South Pacific subtropical gyre: Increased plastic ingestion by fish in the oceanic accumulation zone.

Mar Pollut Bull 2018 Nov 6;136:547-564. Epub 2018 Oct 6.

University of Auckland, School of Environment, Auckland 1010, New Zealand.

Fish are an important food source for South Pacific (SP) island countries, yet there is little information on contamination of commercial marine fish species by plastic. The aim of our study was to perform a broad-scale assessment of plastic ingestion by fish common in the diet of SP inhabitants. We examined 932 specimens from 34 commercial fish species across four SP locations, and some of the prey they ingested, for the presence of marine plastics. Read More

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November 2018

Asking for Feedback: Clinical Nurses' Perceptions of a Peer Review Program in a Community Hospital.

J Nurs Adm 2018 Nov 28. Epub 2018 Nov 28.

Author Affiliations: Co-Magnet® Program Director (Former Associate Chief Nurse) (Dr Bowen-Brady), Brigham and Women's Faulkner Hospital, Boston, Massachusetts; Consultant (Dr Haag-Heitman), Nursing Consultant Partners, Whitefish Bay, Wisconsin; Associate Dean and Associate Professor (Dr Hunt), Professor (Dr Oot-Hayes), School of Nursing, Regis College, Weston, Massachusetts.

Objective: The purpose of this study was to understand clinical nurses' perceptions of their participation in a formal, annual peer review process at a metropolitan community hospital.

Background: Peer review is an essential component of professional nursing practice for self-regulation of the practice and promotion of quality and safety. Robust empirical evidence of formalized and effective peer review nursing processes is not evident. Read More

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November 2018
1 Read

Neurodevelopmental outcomes of extremely preterm infants in New South Wales and the Australian Capital Territory.

J Paediatr Child Health 2018 Nov 30. Epub 2018 Nov 30.

Department of Newborn Care, Royal Hospital for Women, Sydney, New South Wales, Australia.

Aim: This study aimed to provide updated information on gestation-specific neurodevelopmental outcomes of extremely to very preterm infants 23-28 weeks' gestation admitted to neonatal intensive care units (NICUs).

Methods: This was a population-based retrospective cohort study of infants born between 23 and 28 weeks' gestation and admitted to a network of NICUs between 2007 and 2012 in a well-defined geographic area of New South Wales (NSW) and the Australian Capital Territory (ACT). Primary outcome was moderate to severe neurodevelopmental impairment. Read More

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November 2018

Management factors and clinical implications of glandular and squamous gastric disease in horses.

J Vet Intern Med 2018 Nov 29. Epub 2018 Nov 29.

School of Veterinary Medicine and Science, University of Nottingham, Nottingham, United Kingdom.

Background: To date, risk factors for equine glandular gastric disease (EGGD) have not been described in Thoroughbred racehorses.

Objectives: To determine management factors associated with EGGD, identify clinical signs in affected horses, and compare these to equine squamous gastric disease (ESGD).

Animals: The study was carried out on 109 Thoroughbred racehorses from 8 training yards (3 in the United Kingdom and 5 in Australia). Read More

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November 2018

Identification of expressed R-genes associated with leaf spot diseases in cultivated peanut.

Mol Biol Rep 2018 Nov 30. Epub 2018 Nov 30.

Department of Crop, Soil and Environmental Sciences, Auburn University, 258 Funchess Hall, Auburn, AL, 36849, USA.

Peanut (Arachis hypogaea L.) is an important food and oilseed crop worldwide. Yield and quality can be significantly reduced by foliar fungal diseases, such as early and late leaf spot diseases. Read More

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November 2018

Economic analysis of pharmacist-administered influenza vaccines in Ontario, Canada.

Clinicoecon Outcomes Res 2018 24;10:655-663. Epub 2018 Oct 24.

School of Pharmacy, Faculty of Science, University of Waterloo, Waterloo, ON, Canada.

Objective: The aim of this study was to evaluate the impact of pharmacist administration of influenza vaccine in Ontario on: 1) vaccination-associated costs related to the number of people vaccinated; 2) annual influenza-related outcomes and costs; and 3) change in productivity costs.

Methods: Using available data for Ontario, the total number of vaccinations given by providers in the 2011/12 influenza season (pre) was compared to the 2013/14 influenza season (post). Vaccine costs and provider fees for administration were assigned for both periods. Read More

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October 2018
1 Read

Randomized trial of a web-based survivor intervention on melanoma prevention behaviors of first-degree relatives.

Cancer Causes Control 2018 Nov 27. Epub 2018 Nov 27.

Bioethics and Humanities, University of Washington, Seattle, WA, 98195, USA.

Objectives: Melanoma can be prevented through reducing sun exposure and detected early by increasing examination of skin for lesions. First-degree relatives of melanoma cases have higher risk than the general population and, therefore, could be targets of behavioral interventions through families. We tested the effects of a family-based web delivered intervention to melanoma families on the melanoma risk reduction behaviors of first-degree relatives of melanoma cases. Read More

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November 2018
2 Reads

Aggressive nutrition intervention reduces ascites and frequency of paracentesis in malnourished patients with cirrhosis and ascites.

JGH Open 2017 Nov 31;1(3):92-97. Epub 2017 Oct 31.

Liver Injury and Cancer Centenary Research Institute Sydney New South Wales Australia.

Background And Aim: Alterations in nutrient metabolism, nutritional requirements, and reduced dietary intakes are common in chronic liver disease (CLD). These result in malnutrition, sarcopenia, and exacerbate progression to decompensation and ascites. We aimed to investigate the effects of continuous tube feeding (TF) on nutritional status and levels of ascites in malnourished individuals with decompensated cirrhosis. Read More

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November 2017

Compensatory regrowth of the mouse bladder after partial cystectomy.

PLoS One 2018 26;13(11):e0206436. Epub 2018 Nov 26.

Developmental Biology, Stanley Manne Children's Research Institute, Anne and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States of America.

Cystectomy is the removal of all or part of the urinary bladder. It has been observed that there is significant regrowth of the bladder after partial cystectomy and this has been proposed to be through regeneration of the organ. Regrowth of tissue in mammals has been proposed to involve compensatory mechanisms that share many characteristics of true regeneration, like the growth of specialized structures such as blood vessels or nerves. Read More

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November 2018
2 Reads

Toll-like receptor/interleukin-1 domain innate immune signalling pathway genetic variants are candidate predictors for severe gastrointestinal toxicity risk following 5-fluorouracil-based chemotherapy.

Cancer Chemother Pharmacol 2018 Nov 24. Epub 2018 Nov 24.

Cancer Treatment Toxicities Group, Adelaide Medical School, Disciplines of Pharmacology and Physiology, University of Adelaide, Level 2, Helen Mayo South Building, Adelaide, SA, 5005, Australia.

Purpose: Severe gastrointestinal (GI) toxicity is a common adverse effect following 5-fluorouracil (5-FU)-based chemotherapy treatment. The presence of severe GI toxicity leads to treatment revisions, sub-optimal therapy outcomes, and decreases to patients' quality of life. There are no adequate predictors for 5-FU-induced severe GI toxicity risk. Read More

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November 2018

Raja yoga meditation and medication-assisted treatment for relapse prevention: A pilot study.

J Subst Abuse Treat 2019 Jan 26;96:58-64. Epub 2018 Oct 26.

University of Louisiana at Lafayette, United States of America.

The continued need for advancement in evidence-based SUD treatment, as well as increases in treatment expense and decline in support from insurance providers, suggest that brief, innovative, and affordable treatments are needed. Meditation, spirituality, and adherence to medication-assisted treatments have all been shown to support abstinence. The current trial assessed effects of spiritually-based meditation, versus relaxation or standard treatment, on substance abstinence and psychological distress and dysfunction in a partially buprenorphine-supported (41. Read More

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January 2019

Use of the Worklife and Levels of Burnout Surveys to Assess the School Nurse Work Environment.

J Sch Nurs 2018 Nov 22:1059840518813697. Epub 2018 Nov 22.

1 School of Nursing, The State University of New Jersey, Newark, NJ, USA.

Previous research regarding burnout in acute care settings revealed that positive work environments increase job satisfaction, decrease staff turnover, and improve patient outcomes. However, few studies address burnout among school nurses. The purpose of this study was to describe the relationship between the school nurse practice environment, school nurses' levels of burnout, and perceived sources of work stress. Read More

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November 2018
2 Reads

Racial/ethnic measurement invariance of the School Success Profile (SSP)'s future orientation scale.

J Sch Psychol 2018 Dec 16;71:85-107. Epub 2018 Nov 16.

Silver School of Social Work, New York University, 1 Washington Square North, New York, NY 10003, United States of America; McSilver Institute for Poverty Policy and Research, 41 East 11th Street, Room 704, New York, NY 10003, United States of America. Electronic address:

Future orientation (FO) has received increasing attention for its positive effects on adolescent well-being and successful transition to adulthood. Although numerous measures of FO exist, most are not developmentally appropriate for diverse populations of adolescents, do not assess all theoretical components of FO, and/or were not developed for administration in schools. Additionally, the invariance of existing measures across racial/ethnic groups has not been examined using appropriately rigorous procedures. Read More

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December 2018
2 Reads

Model-Based and Model-Free Techniques for Amyotrophic Lateral Sclerosis Diagnostic Prediction and Patient Clustering.

Neuroinformatics 2018 Nov 20. Epub 2018 Nov 20.

Statistics Online Computational Resource, Department of Health Behavior and Biological Sciences, University of Michigan, Ann Arbor, MI, 48109, USA.

Amyotrophic lateral sclerosis (ALS) is a complex progressive neurodegenerative disorder with an estimated prevalence of about 5 per 100,000 people in the United States. In this study, the ALS disease progression is measured by the change of Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) score over time. The study aims to provide clinical decision support for timely forecasting of the ALS trajectory as well as accurate and reproducible computable phenotypic clustering of participants. Read More

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November 2018
5 Reads

Single Cell Transcriptomics Reveal Abnormalities in Neurosensory Patterning of the Mutant Mouse Ear.

Front Genet 2018 23;9:473. Epub 2018 Oct 23.

Medical Scientist Training Program, University of Michigan, Ann Arbor, MI, United States.

The chromatin remodeling protein CHD7 is critical for proper formation of the mammalian inner ear. Humans with heterozygous pathogenic variants in exhibit CHARGE syndrome, characterized by hearing loss and inner ear dysplasia, including abnormalities of the semicircular canals and Mondini malformations. heterozygous null mutant mice also exhibit dysplastic semicircular canals and hearing loss. Read More

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October 2018
2 Reads

Equus caballus papillomavirus 8 (EcPV8) associated with multiple viral plaques, viral papillomas, and squamous cell carcinoma in a horse.

Equine Vet J 2018 Nov 19. Epub 2018 Nov 19.

Department of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, NY, 14853, USA.

Background: Equus caballus papillomavirus 8, a recently discovered virus, has been reported to cause generalised papillomavirus in horses OBJECTIVES: To describe a case in which multiple viral plaques, viral papillomas, squamous cell carcinoma (SCC) in situ and invasive squamous cell carcinoma (ISCC) were associated with EcPV8 in a horse.

Study Design: Case report.

Methods: A 16-year-old mixed breed horse presented with dozens of raised crusted papular to nodular lesions over the course of 4 years. Read More

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November 2018

Hepatitis B virus infection among sexually active individuals in Nigeria: a cross-sectional study.

Pan Afr Med J 2018 20;30:155. Epub 2018 Jun 20.

Department of Virology, College of Medicine University of Ibadan, Nigeria.

Introduction: Hepatitis B virus (HBV) infection is a major health challenge in sub-Saharan African countries. Chronic HBV infection is a risk factor for severe disease progression. Perinatal and sexual transmissions of Hepatitis B virus are the main routes of infection in HBV endemic countries like Nigeria. Read More

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June 2018
3 Reads

The Cancer Prevention Project of Philadelphia: preliminary findings examining diversity among the African diaspora.

Ethn Health 2018 Nov 19:1-17. Epub 2018 Nov 19.

a Cancer Prevention and Control Program , Fox Chase Cancer Center-Temple Health , Philadelphia , USA.

Objective: Cancer mortality inequity among persons of African Ancestry is remarkable. Yet, Black inclusion in cancer biology research is sorely lacking and warrants urgent attention. Epidemiologic research linking African Ancestry and the African Diaspora to disease susceptibility and outcomes is critical for understanding the significant and troubling health disparities among Blacks. Read More

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November 2018
3 Reads

Neutropenia in Barth syndrome: characteristics, risks, and management.

Curr Opin Hematol 2019 Jan;26(1):6-15

Department of Medicine, University of Washington, Seattle, Washington, USA.

Purpose Of Review: Barth syndrome (BTHS) is an X-linked disease characterized by defective remodeling of phospholipid side chains in mitochondrial membranes. Major features include neutropenia, dilated cardiomyopathy, motor delay and proximal myopathy, feeding problems, and constitutional growth delay. We conducted this review of neutropenia in BTHS to aid in the diagnosis of this disease, and to improve understanding of both the consequences of neutropenia and the benefits of treatment with granulocyte colony-stimulating factor (G-CSF). Read More

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January 2019
7 Reads

Chemical constituents, cytotoxic and antioxidant activities of extract from the rhizomes of Osmunda japonica Thunb.

Nat Prod Res 2018 Nov 16:1-4. Epub 2018 Nov 16.

b Beijing Institute of Radiation Medicine , Beijing , China.

Thirty-three compounds (1-33) were isolated from the rhizomes of Osmunda japonica. Their structures were elucidated on the basis of spectral analysis and identified as ent-kaurene terpenoids (1-3), anthraquinones (4-8), flavonoids (9-12), steroids (13-15), and other compounds (16-33). Compound 1-14, 19-27 were isolated from the genus osmunda for the first time. Read More

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November 2018
3 Reads
0.920 Impact Factor

Tralokinumab did not demonstrate oral corticosteroid-sparing effects in severe asthma.

Eur Respir J 2018 Nov 15. Epub 2018 Nov 15.

AstraZeneca, Gaithersburg, Maryland, USA.

Long-term oral corticosteroid (OCS) use in patients with severe asthma is associated with significant adverse effects.This 40-week, randomised, double-blind trial evaluated the OCS-sparing potential of tralokinumab in patients with severe, uncontrolled asthma requiring maintenance OCS treatment plus inhaled corticosteroids/long-acting β-agonists. Overall, 140 patients were randomised to tralokinumab 300 mg or placebo (n=70 each) administered subcutaneously every 2 weeks. Read More

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November 2018

Reporting Harassment and Stalking to the Police: A Qualitative Study of Victims' Experiences.

J Interpers Violence 2018 Nov 15:886260518811423. Epub 2018 Nov 15.

1 University of Worcester, St Johns, UK.

To date, there have been few studies with victims of stalking in the United Kingdom, and this is the first to have been conducted following the clarification of stalking as a criminal offense in 2012. In 2016, Her Majesty's Inspectorate of Constabulary Fire and Rescue Services (HMICFRS) and Her Majesty's Crown Prosecution Inspectorate (HMCPSI) announced the first ever inspection into harassment and stalking in England and Wales. This article presents research commissioned by HMICFRS as part of the inspection. Read More

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November 2018

"There is nothing so practical as a good theory": a pragmatic guide for selecting theoretical approaches for implementation projects.

BMC Health Serv Res 2018 Nov 14;18(1):857. Epub 2018 Nov 14.

Adelaide Nursing School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, 5000, Australia.

Background: A multitude of theories, models and frameworks relating to implementing evidence-based practice in health care exist, which can be overwhelming for clinicians and clinical researchers new to the field of implementation science. Clinicians often bear responsibility for implementation, but may be unfamiliar with theoretical approaches designed to inform or understand implementation.

Main Text: In this article, a multidisciplinary group of clinicians and health service researchers present a pragmatic guide to help clinicians and clinical researchers understand what implementation theories, models and frameworks are; how a theoretical approach to implementation might be used; and some prompts to consider when selecting a theoretical approach for an implementation project. Read More

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November 2018
2 Reads

Mechanisms and Role of Dendritic Membrane Trafficking for Long-Term Potentiation.

Front Cell Neurosci 2018 30;12:391. Epub 2018 Oct 30.

Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO, United States.

Long-term potentiation (LTP) of excitatory synapses is a major form of plasticity for learning and memory in the central nervous system. While the molecular mechanisms of LTP have been debated for decades, there is consensus that LTP induction activates membrane trafficking pathways within dendrites that are essential for synapse growth and strengthening. Current models suggest that key molecules for synaptic potentiation are sequestered within intracellular organelles, which are mobilized by synaptic activity to fuse with the plasma membrane following LTP induction. Read More

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October 2018
1 Read

The Development of an Effective Bacterial Single-Cell Lysis Method Suitable for Whole Genome Amplification in Microfluidic Platforms.

Micromachines (Basel) 2018 Jul 25;9(8). Epub 2018 Jul 25.

Department of Surgery, Division of Surgical Research, Mayo Clinic, Rochester, MN 55905, USA.

Single-cell sequencing is a powerful technology that provides the capability of analyzing a single cell within a population. This technology is mostly coupled with microfluidic systems for controlled cell manipulation and precise fluid handling to shed light on the genomes of a wide range of cells. So far, single-cell sequencing has been focused mostly on human cells due to the ease of lysing the cells for genome amplification. Read More

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Ameliorative effect of low-dose spironolactone on obesity and insulin resistance is through replenishment of estrogen in ovariectomized rats.

Can J Physiol Pharmacol 2018 Nov 13. Epub 2018 Nov 13.

University of Ilorin, Ilorin, Nigeria, Cardiovascular Research Laboratory, Department of Physiology, , P.M.B. 1515 , Ilorin, Kwara, Nigeria , 240003 ;

Women have a lower incidence of cardiovascular diseases (CVD) than men at a similar age but the reverse is the case after menopause, indicating a possible protective effect of estrogen on cardiometabolic function. Obesity with insulin resistance is closely linked to CVD risks while ovariectomized rodents have been shown to mimic obese-insulin resistant (IR) state. We therefore hypothesized that low-dose spironolactone, would ameliorate obese-IR in estrogen-deprived rats by replenishing estrogen and suppressing elevated glycogen synthase kinase-3 (GSK-3). Read More

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November 2018
4 Reads
1.550 Impact Factor

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.

Alzheimers Dement (Amst) 2018 22;10:595-598. Epub 2018 Sep 22.

NHLBI's Framingham Heart Study, Framingham, MA, USA.

Introduction: There is conflicting evidence whether high-density lipoprotein cholesterol (HDL-C) is a risk factor for Alzheimer's disease (AD) and dementia. Genetic variation in the cholesteryl ester transfer protein () locus is associated with altered HDL-C. We aimed to assess AD risk by genetically predicted HDL-C. Read More

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September 2018
3 Reads

Using Theory to Understand the Barriers to Engagement in Group Offending Behavior Programs.

Int J Offender Ther Comp Criminol 2018 Nov 12:306624X18812040. Epub 2018 Nov 12.

1 Coventry University, UK.

Noncompletion of group offending behavior programs is a common problem, indicating barriers to engagement. While existing theoretical models have accounted for determinants of motivation, little focus has been directed towards barriers to engagement. The authors developed the program engagement theory (PET) which not only accounts for the determinants of engagement and the engagement process, it also considers the barriers to engagement. Read More

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November 2018

Preliminary study: Factor structure and psychometric properties of Affective Lability Scale-18 in pregnant and postpartum women.

J Affect Disord 2018 Nov 5;245:312-320. Epub 2018 Nov 5.

College of Nursing, University of Saskatchewan, 104 Clinic Place Saskatoon, SK, S7N 5E5 Canada.

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November 2018
1 Read

Proportion of Violent Injuries Unreported to Law Enforcement.

JAMA Intern Med 2018 Nov 12. Epub 2018 Nov 12.

Division of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia.

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November 2018
1 Read

Development of an In Vitro Model of Inflammatory Cytokine Influences on Intervertebral Disk Cells in 3D Cell Culture Using Activated Macrophage-Like THP-1 Cells.

Bull Exp Biol Med 2018 Nov 12;166(1):151-154. Epub 2018 Nov 12.

Barrow Neurological Institute, Phoenix, AZ, USA.

We developed a new model for evaluation of the influence of proinflammatory cytokines on intervertebral disc cells in a 3D culture based on co-culturing of these cells with activated macrophage-like THP-1 cells. The levels of TNFα, IL-1β, IL-6, IL-8, IL-10, and IL-12p70 production were assessed by flow cytofluorometry using microspheres. Considerable differences in the level of spontaneous cytokine secretion by normal and degenerated intervertebral disc cells were revealed. Read More

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November 2018

Indium Phosphide Photonic Integrated Circuits for Free Space Optical Links.

IEEE J Sel Top Quantum Electron 2018 Nov 23;24(6). Epub 2018 Aug 23.

Department of Electrical and Computer Engineering, University of California Santa Barbara, Santa Barbara, CA 93106, USA

An indium phosphide (InP)-based photonic integrated circuit (PIC) transmitter for free space optical communications was demonstrated. The transmitter consists of a sampled grating distributed Bragg reflector (SGDBR) laser, a high-speed semiconductor optical amplifier (SOA), a Mach-Zehnder modulator, and a high-power output booster SOA. The SGDBR laser tunes from 1521 nm to 1565 nm with >45 dB side mode suppression ratio. Read More

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November 2018
3 Reads

A Review of the Effects of Physical Therapy on Self-Esteem in Postpartum Women With Lumbopelvic Dysfunction.

J Obstet Gynaecol Can 2018 Nov 7. Epub 2018 Nov 7.

Bourassa and Associates Rehabilitation Centre, Saskatoon, SK.

This study sought to determine the impact of physical therapy for lumbopelvic dysfunction on self-esteem in postpartum women. Systematic searches were carried out in CINAHL, Embase, PsycINFO, Medline (OVID), Cochrane, and Web of Science by a health sciences librarian using various combinations of subject headings and key words. A dual review process was used first to assess titles and abstracts and then to examine the full text. Read More

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November 2018
2 Reads

Offering better equine dentistry services.

Authors:

Vet Rec 2018 Nov;183(18):575

Horse owner Anna Bowen describes why she uses a vet rather than an equine dentist for her horse's teeth. Read More

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November 2018

Automated CT Perfusion Prediction of Large Vessel Acute Stroke from Intracranial Atherosclerotic Disease.

Interv Neurol 2018 Oct 17;7(6):334-340. Epub 2018 May 17.

Emory University/Grady Memorial Hospital - Marcus Stroke and Neuroscience Center, Atlanta, Georgia, USA.

Background And Purpose: We have observed that large vessel occlusion acute strokes (LVOS) due to intracranial atherosclerotic disease (ICAD) present with more benign CT perfusion (CTP) profiles, which we presume to potentially represent enhanced collateralization compared to embolic LVOS. We aim to determine if CTP profiles can predict ICAD in LVOS.

Methods: Retrospective review of a prospectively collected interventional stroke database from September 2010 to March 2015. Read More

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October 2018
3 Reads

Resection versus preservation of the middle turbinate in surgery for chronic rhinosinusitis with nasal polyposis: a randomized controlled trial.

J Otolaryngol Head Neck Surg 2018 Nov 8;47(1):67. Epub 2018 Nov 8.

Université de Sherbrooke, 580 Rue Bowen S, Sherbrooke, QC, J1G 2E8, Canada.

Background: Chronic rhinosinusitis (CRS) affects up to 16% of the population. When medical treatment fails, endoscopic sinus surgery (ESS) is considered. The value of resecting the middle turbinate to optimize surgical outcomes has been hypothesized but remains controversial and unproven. Read More

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November 2018
2 Reads

Structural Correlations and Percolation in Twisted Perylene Diimides Using a Simple Anisotropic Coarse-Grained Model.

J Chem Theory Comput 2018 Nov 20. Epub 2018 Nov 20.

Institute for Molecular Engineering, University of Chicago , Chicago , Illinois 60615 , United States.

Large, twisted, and fused conjugated molecular architectures have begun to appear more prominently in the organic semiconductor literature. From a modeling perspective, such structures present a challenge to conventional simulation techniques; atomistic resolutions are computationally inefficient, while traditional isotropic coarse-grained models do not capture the inherent anisotropies of the molecules. In this work, we develop a simple coarse-grained model that explicitly incorporates the anisotropy of these molecular architectures, thereby providing a route toward analyzing π-stacking, and thus qualitative electronic structure, at a computationally efficient coarse-grained resolution. Read More

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November 2018
3 Reads

What do people think about genetics? A systematic review.

J Community Genet 2018 Nov 7. Epub 2018 Nov 7.

University of Washington, Box 357120, Seattle, WA, 98195, USA.

Genetics is increasingly becoming a part of modern medical practice. How people think about genetics' use in medicine and their daily lives is therefore essential. Earlier studies indicated mixed attitudes about genetics. Read More

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November 2018
2 Reads

A rare x-ray image of emphysematous cystitis.

Urol Case Rep 2019 Jan 25;22:40-41. Epub 2018 Oct 25.

Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Queensland, 4102, Australia.

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January 2019