Clearance of human papillomavirus related anal condylomas after oral and endorectal multistrain probiotic supplementation in an HIV positive male: A case report.
- Giancarlo Ceccarelli,
- Eugenio Nelson Cavallari,
- Stefano Savinelli,
- Luigi Bianchi,
- Alessandra Pierangeli,
- Francesco Vullo,
- Antonio Ciardi,
- Gabriella D'ettorre
Medicine (Baltimore) 2018 Apr;97(16):e0329
Department of Public Health and Infectious Diseases.
Introduction: Here we present the case of a 56-year-old human immunodeficiency virus (HIV)-infected man with multiple anal condylomas and positivity for human papilloma virus (HPV) 18 on anal brushing. Biopsies of the anal mucosa led to the diagnosis of Bowen's disease and a subsequent pelvic magnetic resonance imaging (MRI) scan evidenced multiple reactive lymphoadenopathies and large intra-anal condylomas. The patient was treated with a complete excision of Bowen's lesion and with a 4 months course of supplementation with a high concentration multistrain probiotic formulation administered orally and by rectal instillation with the purpose to reduce local inflammation and to enhance local mucosal immunity. Read More