28,264 results match your criteria Bowel Trauma

Case Report: Rectal Perforation Secondary to a Toothbrush in an Elderly Man.

Front Surg 2022 10;9:921843. Epub 2022 Jun 10.

Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.

Rectal foreign bodies often constitute an arduous diagnosis and perplexing management. A 72-year-old gentleman who is mentally sound was brought to the emergency department for severe epigastric pain of a 1-week duration. On examination, he was pyrexial and in sepsis. Read More

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Time from Injury to Initial Operation May Be the Sole Risk Factor for Postoperative Leakage in AAST-OIS 2 and 3 Traumatic Duodenal Injury: A Retrospective Cohort Study.

Medicina (Kaunas) 2022 Jun 14;58(6). Epub 2022 Jun 14.

Division of Trauma, Department of Surgery, Chonnam National University Medical School and Hospital, Chonnam National University, Gwangju 61469, Korea.

: Traumatic duodenal injury is a rare disease with limited evidence. We aimed to evaluate the risk factors for postoperative leakage and outcomes of pyloric exclusion after duodenal grade 2 and 3 injury. : We reviewed a prospectively collected trauma database for the period January 2004-December 2020. Read More

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Pediatric Spina Bifida and Spinal Cord Injury.

J Pers Med 2022 Jun 17;12(6). Epub 2022 Jun 17.

Department of Physical Medicine and Rehabilitation, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.

Pediatric spina bifida (SB) and spinal cord injury (SCI) are unfortunately common in our society, and their unique findings and comorbidities warrant special consideration. This manuscript will discuss the epidemiology, pathophysiology, prevention, and management strategies for children growing and developing with these unique neuromuscular disorders. Growth and development of the maturing child places them at high risk of spinal cord tethering, syringomyelia, ascending paralysis, pressure injuries, and orthopedic abnormalities that must be addressed frequently and judiciously. Read More

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Congenital ileal-mesenteric fibrous band remnant of the vitelline artery causing small bowel obstruction in an adult female: a case report.

Pan Afr Med J 2022 1;41:269. Epub 2022 Apr 1.

Department of Surgery, Potchefstroom Hospital, Potchefstroom, South Africa.

The vitelline circulation connects the fetus and yolk sac in the first few weeks of fetal development. Its components are the vitelline duct, vitelline arteries and vitelline vein. This gradually breaks down as the placenta grows and overtakes the function of yolk sac as the primary nutrition source. Read More

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The Impact of Supplements on Recovery After Peripheral Nerve Injury: A Review of the Literature.

Cureus 2022 May 19;14(5):e25135. Epub 2022 May 19.

Plastic Surgery, Cleveland Clinic, Cleveland, USA.

Peripheral nerve injury (PNI) can result from trauma, surgical resection, iatrogenic injury, and/or local anesthetic toxicity. Damage to peripheral nerves may result in debilitating weakness, numbness, paresthesia, pain, and/or autonomic instability. As PNI is associated with inflammation and nerve degeneration, means to mitigate this response could result in improved outcomes. Read More

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Midazolam premedication in ileocolic intussusception: a retrospective multicenter study.

Eur J Pediatr 2022 Jun 22. Epub 2022 Jun 22.

Department of Emergency Medicine and Trauma Center, Meyer University Children's Hospital, Florence, Italy.

Ileocolic intussusception is a common cause of bowel obstruction. When spontaneous reduction does not occur, non-operative management through enema reduction is necessary. Despite the evidence indicating that sedatives favor success in the reduction, their use is still not a common practice. Read More

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Intraoperative complications in kidney tumor surgery: critical grading for the European Association of Urology intraoperative adverse incident classification.

Scand J Urol 2022 Jun 22:1-8. Epub 2022 Jun 22.

Deparment of Urology, Tampere University Hospital and University of Tampere, Tampere, Finland.

Introduction: The European Association of Urology committee in 2020 suggested a new classification, intraoperative adverse incident classification (EAUiaiC), to grade intraoperative adverse events (IAE) in urology.

Aims: We applied and validated EAUiaiC, for kidney tumor surgery.

Patients And Methods: A retrospective multicenter study was conducted based on chart review. Read More

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FG-4592 protects the intestine from irradiation-induced injury by targeting the TLR4 signaling pathway.

Stem Cell Res Ther 2022 Jun 21;13(1):271. Epub 2022 Jun 21.

School of Public Health and Management, Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China.

Background: Severe ionizing radiation (IR)-induced intestinal injury associates with high mortality, which is a worldwide problem requiring urgent attention. In recent years, studies have found that the PHD-HIF signaling pathway may play key roles in IR-induced intestinal injury, and we found that FG-4592, the PHD inhibitor, has significant radioprotective effects on IR-induced intestinal injury.

Methods: In the presence or absence of FG-4592 treatment, the survival time, pathology, cell viability, cell apoptosis, and organoids of mice after irradiation were compared, and the mechanism was verified after transcriptome sequencing. Read More

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Fluoxetine reduces organ injury and improves motor function after traumatic brain injury in mice.

J Trauma Acute Care Surg 2022 Jul 12;93(1):38-42. Epub 2022 Apr 12.

From the Department of Surgery, Division of Trauma, Surgical Critical Care, Burns, and Acute Care Surgery, UC San Diego, San Diego, California.

Background: Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in trauma patients worldwide. Brain injury is associated with significant inflammation, both within the brain and in the peripheral organs. This inflammatory response in TBI leads to a secondary injury, worsening the effects of the original brain injury. Read More

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The influence of preoperative CT imaging on surgical delay in patients with acutely symptomatic abdominal wall hernias.

Eur J Trauma Emerg Surg 2022 Jun 21. Epub 2022 Jun 21.

Department of Gastrointestinal Surgery, Arrowe Park University Teaching Hospital, Arrow Park Rd, Birkenhead, CH49 5PE, Wirral, UK.

Purpose: Abdominal wall hernias are common in the UK and many present in an emergent fashion. The widespread introduction of computed tomography (CT) imaging has transformed surgical practice but out of hours access can be limited by hospital resources and introduce delays. We investigated the influence of preoperative CT imaging in acutely symptomatic hernia and the association with surgical delay and risks of bowel ischemia. Read More

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Radiodermatitis: severity, predictive factors and discontinuation of radiotherapy in patients with anal and rectal cancer.

Rev Esc Enferm USP 2022 15;56:e20210378. Epub 2022 Jun 15.

Instituto Nacional de Câncer José Alencar Gomes da Silva, Programa de Residência Multiprofissional em Oncologia, Rio de Janeiro, RJ, Brazil.

Objective: to determine the prevalence of radiodermatitis, severity grades and predictive factors of its occurrence in patients with anal and rectal cancer followed up by the nursing consultation, and to analyze the association of severity grades of radiodermatitis with temporary radiotherapy interruption.

Method: a quantitative, cross-sectional and retrospective study, carried out with 112 medical records of patients with anal and rectal cancer undergoing curative radiotherapy followed up in the nursing consultation. Data were collected using a form and analyzed using analytical and inferential statistics. Read More

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Alpha-Lipoic Acid Promotes Intestinal Epithelial Injury Repair by Regulating MAPK Signaling Pathways.

Mediators Inflamm 2022 7;2022:1894379. Epub 2022 Jun 7.

Department of Gastrointestinal Surgery I Section, Renmin Hospital of Wuhan University, Wuhan 430060, China.

Intestinal epithelial cells are an essential barrier in human gastrointestinal tract, and healing of epithelial wound is a key process in many intestinal diseases. -Lipoic acid (ALA) was shown to have antioxidative and anti-inflammatory effects, which could be helpful in intestinal epithelial injury repair. The effects of ALA in human colonic epithelial cells NCM460 and human colorectal adenocarcinoma cells Caco-2 were studied. Read More

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Three-Dimensional Ultrasound Imaging under Optimized Nuclear Regression Reconstruction Algorithm in the Diagnosis Vaginal Delivery and Cesarean Section on the Anal Sphincter Complex of Primiparas.

Comput Math Methods Med 2022 7;2022:6173460. Epub 2022 Jun 7.

Department of Obstetrics and Gynecology, Wuhan First Hospital, Wuhan 430022, China.

This study was aimed at analyzing the injury of anal sphincter (AS) for primipara caused by the vaginal delivery and cesarean section under the guidance of three-dimensional (3D) ultrasound images. A total of 160 patients who underwent postpartum reexamination were enrolled as the research subjects, including 80 cases of natural delivery (group A) and 80 cases of cesarean section pregnant women (group B), all of whom underwent three-dimensional ultrasound imaging scans. At the same time, an optimized kernel regression reconstruction (KRR) algorithm was proposed for the enhancement of ultrasound images. Read More

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The Scientific Rationale for the Introduction of Renalase in the Concept of Cardiac Fibrosis.

Front Cardiovasc Med 2022 31;9:845878. Epub 2022 May 31.

Institute of Pathophysiology, Faculty of Medicine, University of Niš, Niš, Serbia.

Cardiac fibrosis represents a redundant accumulation of extracellular matrix proteins, resulting from a cascade of pathophysiological events involved in an ineffective healing response, that eventually leads to heart failure. The pathophysiology of cardiac fibrosis involves various cellular effectors (neutrophils, macrophages, cardiomyocytes, fibroblasts), up-regulation of profibrotic mediators (cytokines, chemokines, and growth factors), and processes where epithelial and endothelial cells undergo mesenchymal transition. Activated fibroblasts and myofibroblasts are the central cellular effectors in cardiac fibrosis, serving as the main source of matrix proteins. Read More

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Perioperative and oncologic outcomes of interval colectomy performed by acute care surgeons after stenting as a bridge to surgery for left-sided malignant colonic obstruction are non-inferior to the outcomes of colorectal surgeons in the elective setting: single center experience.

Eur J Trauma Emerg Surg 2022 Jun 16. Epub 2022 Jun 16.

Head-in-Chief. General, Digestive and Transplantation Surgery Department, University Regional Hospital, Malaga, Spain.

Purpose: To analyze if perioperative and oncologic outcomes with stenting as a bridge to surgery (SEMS-BS) and interval colectomy performed by acute care surgeons for left-sided occlusive colonic neoplasms (LSCON) are non-inferior to those obtained by colorectal surgeons for non-occlusive tumors of the same location in the full-elective context.

Methods: From January 2011 to January 2021, patients with LSCON at University Regional Hospital in Málaga (Spain) were directed to a SEMS-BS strategy with an interval colectomy performed by acute care surgeons and included in the study group (SEMS-BS). The control group was formed with patients from the Colorectal Division elective surgical activity dataset, matching by ASA, stage, location and year of surgery on a ratio 1:2. Read More

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A 28-Year-Old Woman Presenting with a Clinical Flare of Systematic Lupus Erythematosus and Abdominal Pain Due to Rectus Sheath Hematoma.

Am J Case Rep 2022 Jun 15;23:e935472. Epub 2022 Jun 15.

Department of Nephrology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China (mainland).

BACKGROUND A flare, or flare-up, of systematic lupus erythematosus (SLE) is diagnosed by an increase in disease activity in one or more organs, new symptoms, or changes in laboratory measurements. A hematoma can occur in the sheath of the rectus abdominis following muscle trauma or rupture of an epigastric vessel, or it can occur spontaneously. This report is of a 28-year-old woman who presented with a clinical flare of SLE and abdominal pain due to rectus sheath hematoma. Read More

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Bladder and Bowel Dysfunction due to a Spontaneous Spinal Epidural Hematoma Without Paraplegia: A Case Report.

JBJS Case Connect 2022 04 8;12(2). Epub 2022 Jun 8.

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.

Case: A 44-year-old man developed urinary retention due to a spontaneous spinal epidural hematoma (SSEH) at the cervicothoracic junction, without paraplegia. Symptoms improved with surgical treatment.

Conclusion: SSEH is rare and causes acute neck or back pain and progressive paralysis. Read More

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[Stenotic ischemic enteritis secondary to intraperitoneal band infiltration: a case report].

Nihon Shokakibyo Gakkai Zasshi 2022 ;119(6):566-572

Digestive and Lifestyle Diseases, Kagoshima University Graduate School of Medical and Dental Sciences.

A 55-year-old man presented with vomiting and upper abdominal pain. Two months later, computed tomography revealed jejunal wall thickening and contrast enhancement. Double-balloon endoscopy revealed severe jejunal stenosis and mucosal prolapse. Read More

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Retention and loss of PIT tags and surgically implanted devices in the Eurasian beaver.

BMC Vet Res 2022 Jun 10;18(1):219. Epub 2022 Jun 10.

Department of Natural Sciences and Environmental Health, University of South-Eastern Norway, Bø i Telemark, Norway.

Background: Passive integrated transponder devices (PIT tags) are a valuable tool for individual identification of animals. Similarly, the surgical implantation of transmitters and bio-loggers can provide useful data on animal location, physiology and behavior. However, to avoid unnecessary recapture and related stress of study animals, PIT tags and bio-loggers should function reliably for long periods of time. Read More

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The dynamic cellular and molecular features during the development of radiation proctitis revealed by transcriptomic profiling in mice.

BMC Genomics 2022 Jun 9;23(1):431. Epub 2022 Jun 9.

Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.

Background: Radiation proctitis (RP) is the most common complication of radiotherapy for pelvic tumor. Currently there is a lack of effective clinical treatment and its underlying mechanism is poorly understood. In this study, we aimed to dynamically reveal the mechanism of RP progression from the perspective of RNomics using a mouse model, so as to help develop reasonable therapeutic strategies for RP. Read More

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Potential influences of expression levels of MFGE8 and HMGB1 on the intestinal mucosal barrier function and inflammatory response after blunt abdominal injury in rats.

Acta Cir Bras 2022 1;37(3):e370303. Epub 2022 Jun 1.

MD. The First Affiliated Hospital of Wenzhou Medical University - Department of Trauma Surgery (Emergency Surgery) - Wenzhou, China.

Purpose: To explore the influence of milk fat globule-EGF factor 8 protein (MFGE8) on blunt abdominal injury in Sprague Dawley (SD) rats through the RhoA/ROCK signaling pathway.

Methods: The blunt abdominal injury model was generated in SD rats. A total of 44 rats was randomly assigned into three groups. Read More

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Analysis of surgical mortality in rural South Australia: a review of four major rural hospital in South Australia.

ANZ J Surg 2022 Jun 8. Epub 2022 Jun 8.

Discipline of Surgery, The University of Adelaide, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia.

Background: One-third of Australia's population reside in rural and remote areas. This audit aims to describe all-causes of mortality in rural general surgical patients, and identify areas of improvement.

Methods: This is a retrospective multi-centre study involving four South Australian hospitals (Mt Gambier, Whyalla, Port Augusta, and Port Lincoln). Read More

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Knockout Alleviates DSS-Induced Colitis Regulating the Immune Function of Dendritic Cells.

Front Immunol 2022 20;13:841254. Epub 2022 May 20.

Department of Emergency Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.

Background: Dysfunction of the immune system would disturb the intestinal homeostasis and lead to inflammatory bowel disease (IBD). Dendritic cells (DCs) help maintain intestinal homeostasis and immediately respond to pathogens or injuries once the mucosa barriers are destroyed during IBD. G protein-coupled receptors(GPR)174 is an essential regulator of immunity that is widely expressed in most immune cells, including DCs. Read More

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The Utilization and National Variation of Plain X-Ray Services by Australian Residents of Long-Term Care Facilities.

J Am Med Dir Assoc 2022 Jun 3. Epub 2022 Jun 3.

Surgical Specialities, University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia, Australia; Royal Australasian College of Surgeons, Kent Town, South Australia, Australia.

Objectives: To (1) estimate incidence, trends, and determinants of government-subsidized diagnostic radiography (ie, plain x-ray) services utilization by Australian long-term care facility (LTCF) residents between 2009 and 2016; (2) examine national variation in services used.

Design: A repeated cross-sectional study.

Setting And Participants: Australian LTCF residents who were ≥65 years old. Read More

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Prediction of bowel management independence after ischemic spinal cord injury.

Eur J Phys Rehabil Med 2022 Jun 6. Epub 2022 Jun 6.

Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland -

Background: Ischemic spinal cord injury (SCI) belongs to the heterogeneous group of non-traumatic SCI, while the course of sensorimotor and functional recovery is comparable to traumatic SCI. Recently, we derived from data of patients with traumatic SCI a valid model to predict an independent and reliable bowel management one year after SCI.

Aim: To evaluate the performance of this model to predict an independent and reliable bowel management one year following ischemic SCI. Read More

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A rare presentation of delayed traumatic lumbar hernia after motor vehicle collision.

J Surg Case Rep 2022 May 31;2022(5):rjac188. Epub 2022 May 31.

General Surgery, St. Joseph's University Medical Center, Paterson, NJ, USA.

Traumatic abdominal wall hernia is defined as protrusion of bowel or an abdominal organ through a disruption of musculature and fascia following a severe blunt trauma. We report a case of a patient who had a delayed presentation of a traumatic, superiorly located paralumbar hernia months after the initial admission. Read More

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Cancer incidence in a male adult population in relation to estimated protracted colon dose - A nested case control study in Northern Sweden after the Chernobyl Nuclear Power Plant accident.

Sci Total Environ 2022 Sep 31;838(Pt 3):156349. Epub 2022 May 31.

Occupational and Environmental Medicine, Department of Medical Sciences, Uppsala University, Sweden; Occupational and Environmental Medicine, Uppsala University Hospital, Uppsala, Sweden.

Introduction: Uncertainty in the dose-response of low dose radiation raised concern of an increased cancer incidence in Sweden after the Chernobyl Nuclear Power Plant (NPP) accident.

Material And Methods: A closed cohort was created of all males ≥18 years of age living in the Northern Sweden in 1986. In total 826,400 individuals were enrolled including 40,874 hunters. Read More

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September 2022

[Postpartum fecal incontinence. State of the problem].

Khirurgiia (Mosk) 2022 (6):127-132

Lomonosov Moscow State University, Moscow, Russia.

A review of the current national and foreign literature is devoted to epidemiology, risk factors, causes, diagnosis and modern treatment approaches for fecal incontinence (FI). Incidence of FI in early and delayed period after childbirth is 30% or more. At the same time, up to 87% of postpartum injuries of anal sphincter remain undiagnosed. Read More

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Heat stress modulates the disruptive effects of Eimeria maxima infection on the ileum nutrient digestibility, molecular transporters, and tissue morphology in meat-type chickens.

PLoS One 2022 3;17(6):e0269131. Epub 2022 Jun 3.

Department of Poultry Science, University of Georgia, Athens, Georgia, United States of America.

Eimeria (E.) maxima is one of the most pathogenic Eimeria spp persistently invading the middle jejunum and ileum, damaging the intestinal mucosa of chickens. Heat stress (HS) is a common stressor and equally contributes to inflammation and oxidative stress. Read More

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Magnet and button battery ingestion in children: multicentre observational study of management and outcomes.


BJS Open 2022 05;6(3)

Background: Magnets and button batteries (BBs) are dangerous ingested foreign bodies in children. The scale and consequences of this public health issue in the UK are unknown. This study aims to report the current management strategies and outcomes associated with paediatric magnet and BB ingestion in the UK. Read More

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