Bone 2018 Feb 20. Epub 2018 Feb 20.
Department of Biomedicine, Aarhus University, Denmark. Electronic address:
Osteopenia and sarcopenia develops rapidly during disuse. The study investigated whether intermittent parathyroid hormone (1-34) (PTH) and growth hormone (GH) administered alone or in combination could prevent or mitigate disuse osteopenia and sarcopenia in rats. Disuse was achieved by injecting 4 IU botulinum toxin A (BTX) into the right hindlimb musculature of 12-14-week-old female Wistar rats. Read More