2 results match your criteria Bone and Tissue Regeneration Insights [Journal]

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Cornea As a Model for Testing CTGF-Based Antiscarring Drugs.

Bone Tissue Regen Insights 2016 Jan-Dec;7. Epub 2016 Jun 20.

Schepens Eye Research Institute, Boston, MA, USA.

Scarring remains a serious complication of the wound healing process that can lead to the formation of excessive fibrous connective tissue in an organ or tissue leading to pain and loss of function. This process is mainly regulated by Transforming growth factor β1 (TGF-β1), which binds to receptors and induces its downstream mediator, Connective tissue growth factor (CTGF). The number of drugs targeting CTGF for treating scars has been on the rise in the past few years. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982571PMC
http://dx.doi.org/10.4137/BTRI.S19954DOI Listing
June 2016
5 Reads

Nanotechnology in the Regeneration of Complex Tissues.

Authors:
John W Cassidy

Bone Tissue Regen Insights 2014 Nov;5:25-35

Centre for Cell Engineering, University of Glasgow, Glasgow, UK. ; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.

Modern medicine faces a growing crisis as demand for organ transplantations continues to far outstrip supply. By stimulating the body's own repair mechanisms, regenerative medicine aims to reduce demand for organs, while the closely related field of tissue engineering promises to deliver "off-the-self" organs grown from patients' own stem cells to improve supply. To deliver on these promises, we must have reliable means of generating complex tissues. Read More

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http://dx.doi.org/10.4137/BTRI.S12331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471123PMC
November 2014
11 Reads
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