1,270,909 results match your criteria Body Fluid Exposures


Quality of Bowel Preparation for Colonoscopy in Patients with a History of Abdomino-Pelvic Surgery: Retrospective Cohort Study.

Yonsei Med J 2019 Jan;60(1):73-78

Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.

Purpose: Prior abdomino-pelvic (AP) surgery makes colonoscopy difficult and can affect bowel preparation quality. However, bowel preparation quality has been found to vary according to prior AP surgery type. We examined the relationship of prior AP surgery type with bowel preparation quality in a large-scale retrospective cohort. Read More

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January 2019

Serum adipocyte fatty acid-binding protein levels: an indicator of non-alcoholic fatty liver disease in Chinese individuals.

Liver Int 2018 Dec 16. Epub 2018 Dec 16.

Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital; Shanghai Clinical Center for Diabetes; Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, 200233, China.

Background & Aims: Serum adipocyte fatty acid-binding protein (A-FABP) is closely correlated to metabolic disorders such as obesity and insulin resistance (IR). Non-alcoholic fatty liver disease (NAFLD) is a typical feature of IR in the liver. The aim of this study was to explore the relationship between serum A-FABP levels and NAFLD. Read More

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December 2018

Three-Dimensional Printing in Anatomy Education:Assessing Potential Ethical Dimensions.

Authors:
D Gareth Jones

Anat Sci Educ 2018 Dec 15. Epub 2018 Dec 15.

Department of Anatomy, University of Otago, Dunedin, New Zealand.

New technological developments have frequently had major consequences for anatomy education, and have raised ethical queries for anatomy educators. The advent of three-dimensional (3D) printing of human material is showing considerable promise as an educational tool that fits alongside cadaveric dissection, plastination, computer simulation, and anatomical models and images. At first glance its ethical implications appear minimal, and yet the more extensive ethical implications around clinical bioprinting suggest that a cautious approach to 3D printing in the dissecting room is in order. Read More

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December 2018

Fucoxanthin prevents lipopolysaccharide-induced depressive-like behavior in mice via AMPK- NF-κB pathway.

Metab Brain Dis 2018 Dec 15. Epub 2018 Dec 15.

Department of Pharmacy, Institute of toxicology and pharmacology, Zhejiang Pharmaceutical College, Ningbo, 315000, China.

Fucoxanthin (FX), a natural carotenoid abundant in edible brown seaweeds, has been shown the great anti-oxidant, anti-inflammatory and anti-diabetic effects in vivo and in vitro. The present study was designed to investigate the effects of FX on lipopolysaccharide (LPS)-induced behavioral defects in mice. In depressive behavior tests, the increased immobility time of forced swimming test and tail suspension test by LPS treatment in mice, which were significantly reversed by FX treatment (200 mg/kg, i. Read More

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December 2018

The effects of a 12-week jump rope exercise program on abdominal adiposity, vasoactive substances, inflammation, and vascular function in adolescent girls with prehypertension.

Eur J Appl Physiol 2018 Dec 15. Epub 2018 Dec 15.

Department of Physical Education, Pusan National University, Busan, South Korea.

Introduction: Childhood obesity is strongly associated with cardiovascular disease (CVD) development. It is necessary to combat unfavorable outcomes of obesity at a young age by utilizing effective interventions, such as exercise.

Purpose: We sought to examine the effects of a jump rope exercise program on CVD risk factors, including body composition, vasoactive substances, inflammation, and vascular function in prehypertensive adolescent girls. Read More

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December 2018
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Effects of Selenium-Enriched Yeast Improved Aflatoxin B1-Induced Changes in Growth Performance, Antioxidation Capacity, IL-2 and IFN-γ Contents, and Gene Expression in Mice.

Biol Trace Elem Res 2018 Dec 15. Epub 2018 Dec 15.

College of Animal Science and Veterinary Medicine, Tianjin Agricultural University, Tianjin, 300384, China.

Sixty Kunming mice were randomly assigned into three groups. Mice in a control group were fed a basal diet, while mice in AFB1 group and AFB1-Se group were fed the basal diet supplemented with 250 μg/kg AFB1 or the basal diet supplemented with 250 μg/kg AFB1 and 0.2 mg/kg selenium as selenium-enriched yeast, respectively. Read More

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December 2018

Radiotherapy for oligometastatic cancer: a survey among radiation oncologists of Lombardy (AIRO-Lombardy), Italy.

Radiol Med 2018 Dec 15. Epub 2018 Dec 15.

S. C. Radioterapia, ASST dei Sette Laghi-Ospedale di Circolo e Fondazione Macchi, Varese, Italy.

Aims: To evaluate the use of radiotherapy (RT) for oligometastatic cancer (OMC) among radiation oncologists in Lombardy, Italy.

Methods And Study Design: A survey with 12 items regarding data of 2016 was sent to all 34 Lombardy RT centers. The survey included six general items and six specific items regarding patient/disease/treatment characteristics. Read More

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December 2018

Resveratrol Protects Against Renal Damage via Attenuation of Inflammation and Oxidative Stress in High-Fat-Diet-Induced Obese Mice.

Inflammation 2018 Dec 15. Epub 2018 Dec 15.

College of Animal Science and Technology, Nanjing Agricultural University, No. 1 Weigang, Nanjing, 210095, Jiangsu, People's Republic of China.

Oxidative stress and inflammation play an important role in the chronic kidney disease associated with obesity. Resveratrol (RSV) has been reported to exhibit a wide range of biological activities including antioxidant and anti-inflammatory properties. The objective of the present study was to investigate the effects of RSV on renal inflammation and oxidative stress in obese mice induced by high-fat diet. Read More

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December 2018

Adsorption and in vitro release study of curcumin form polyethyleneglycol functionalized multi walled carbon nanotube: kinetic and isotherm study.

Daru 2018 Dec 15. Epub 2018 Dec 15.

Department of Food Science & Technology, Faculty of Food Industry and Agriculture, Standard Research Institute (SRI), Karaj, P.O. Box: 31745-139, Iran.

Polyethylene glycol functionalized with oxygenated multi-walled carbon nanotubes (O-PEG-MWCNTs) as an efficient nanomaterial for the in vitro adsorption/release of curcumin (CUR) anticancer agent. The synthesized material was morphologically characterized using scanning electron microscopy, Fourier transform infrared spectroscopy and transmission electron microscopy. In addition, the CUR adsorption process was assessed with kinetic and isotherm models fitting well with pseudo-second order and Langmuir isotherms. Read More

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December 2018

Metabolic requirements of the nephron.

Pediatr Nephrol 2018 Dec 15. Epub 2018 Dec 15.

Rangos Research Center, UPMC Children's Hospital of Pittsburgh, Pittsburgh, USA.

The mammalian kidney is a complex organ that has several metabolically active cell types to aid in waste filtration, salt-water balance, and electrolyte homeostasis in the body. These functions are done primarily through the nephron, which relies on strict regulation of various metabolic pathways. Any deviations in the metabolic profile of nephrons or their precursor cells called nephron progenitors can lead to renal pathologies and abnormal development. Read More

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December 2018
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Efficacy and Safety of CFTR Corrector and Potentiator Combination Therapy in Patients with Cystic Fibrosis for the F508del-CFTR Homozygous Mutation: A Systematic Review and Meta-analysis.

Adv Ther 2018 Dec 15. Epub 2018 Dec 15.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.

Introduction: Cystic fibrosis (CF) is a progressive, genetic disease that causes persistent lung infections and limits the ability to breathe over time. The combination of a cystic fibrosis transmembrane conductance regulator (CFTR) corrector and potentiator has provided a benefit by decreasing sweat chloride concentration in CF for the F508del-CFTR homozygous mutation, but it remains controversial in lung function, nutritional status, clinical score and safety.

Methods: The authors performed a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the efficacy and safety of combination therapy on lung function, nutritional status, clinical score and safety in CF for the F508del-CFTR homozygous mutation. Read More

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December 2018
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Effect of model race and viewing perspective on body attractiveness and body size assessment in young Caucasian women: an eye-tracking study.

Psychol Res 2018 Dec 15. Epub 2018 Dec 15.

School of Psychology, University of Lincoln, Brayford Pool, Lincoln, LN6 7TS, UK.

Research has indicated that Caucasian women gaze more often at waist-hip and chest regions than other local body areas when assessing female body attractiveness and body size, and this stereotypical gaze distribution is further modulated by their own body satisfaction and body composition. However, little is known whether the model race and viewing perspective could affect women's body-viewing gaze behaviour and body perception. Here, we presented female body images of Caucasian, Asian and African avatars in a continuum of common dress sizes in full frontal, mid-profile and rear view, and asked young Caucasian women to rate the perceived body attractiveness and body size. Read More

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December 2018

Young adult e-cigarette users: perceptions of stress, body image, and weight control.

Eat Weight Disord 2018 Dec 15. Epub 2018 Dec 15.

Westat Cancer Prevention and Control Program, Georgetown University Medical Center, 1600 Research Boulevard, Rockville, MD, 20850-3129, USA.

Objective: With the rise in electronic cigarette (ENDS) use among US young adults, more research is needed on expectations for use and perceptions related to body image, weight control, and stress relief.

Methods: College students (N = 230; modal age 21 years; 68% female) completed an online survey assessing cigarette smoking and ENDS, dieting and body image, perceptions about flavors, stress, weight gain prevention, and appetite regulation.

Sample Characteristics: Dual use (cigarette and ENDS) was reported by n = 69 (30. Read More

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December 2018

Association between REM sleep and obstructive sleep apnea in obese and overweight adolescents.

Sleep Breath 2018 Dec 15. Epub 2018 Dec 15.

Children's Hospital Los Angeles, 4650 Sunset Blvd., #83, Los Angeles, CA, USA.

Purpose: Overweight and obese children have demonstrated reduced rapid eye movement (REM) sleep, affecting energy balance regulation and predisposition to weight gain. Obstructive sleep apnea (OSA) is a known cause of decreased REM sleep. The purpose of this study is to examine the association between the percentage of REM sleep, BMI z-score, and OSA severity in overweight and obese adolescents. Read More

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December 2018

Endodontic sealers based on calcium silicates: a systematic review.

Odontology 2018 Dec 15. Epub 2018 Dec 15.

Central Interdisciplinary Ambulance in the School of Dentistry, Albert-Schweitzer-Campus 1, Building W 30, 48149, Münster, Germany.

Recently, sealers based on calcium silicates were developed as a new class of endodontic sealers. Inspired by the excellent sealing ability and biocompatibility of calcium silicate-based cements, these sealers establish a biological point of view on the obturation of root canals. No longer, the bacteria-tight seal against reinfection of the root canal is the only goal of root canal obturation. Read More

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December 2018

Late systemic symptoms in head and neck cancer survivors.

Support Care Cancer 2018 Dec 15. Epub 2018 Dec 15.

Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, 2220 Pierce Avenue, 777 Preston Research Building, Nashville, TN, 37232, USA.

Purpose: Neuroinflammation and central sensitization from cancer and its therapy may result in chronic systemic symptoms (CSS) such as fatigue, sleep disturbance, chronic widespread pain, mood disorders, neuropsychiatric symptoms, and temperature dysregulation. We undertook a cross-sectional study of CSS in head and neck cancer (HNC) survivors to determine their frequency, severity, and impact.

Methods: HNC patients without evidence of recurrence who were at least 12 months post-treatment completed a one-time battery of self-report measures including the Vanderbilt Head and Neck Symptom survey plus the General Symptom Subscale, the Body Image Quality of Life Inventory, Neurotoxicity Rating Scale, the Profile of Mood States, and a five-item quality of life measure. Read More

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December 2018
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Administrative healthcare data applied to fracture risk assessment.

Osteoporos Int 2018 Dec 15. Epub 2018 Dec 15.

Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Fracture risk scores generated from population-based administrative healthcare data showed comparable or better discrimination than the Fracture Risk Assessment Tool (FRAX) scores computed without bone mineral density for predicting incident major osteoporotic fracture. Administrative data may be useful to identify individuals at high fracture risk at the population level.

Purpose: To evaluate the discrimination of fracture risk scores defined using inputs available from administrative data for predicting incident major osteoporotic fracture (MOF) and hip fracture (HF) alone. Read More

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December 2018

The Relationship between Weight Status and Depressive Symptoms in a Population Sample with Obesity: The Mediating Role of Appearance Evaluation.

Obes Facts 2018 Dec 14;11(6):514-523. Epub 2018 Dec 14.

Integrated Research and Treatment Center (IFB) AdiposityDiseases, University Hospital Leipzig, Leipzig, Germany.

Objectives: Identifying the underlying pathways between obesity and depression and which individuals with obesity are at risk for developing depressive symptoms is important for improving prevention and treatment efforts. The current study investigated appearance evaluation as a potential mediator of the relationship between obesity and depression.

Methods: A total of 1,000 participants with a self-reported BMI greater than 30 kg/m2 were interviewed about their experiences with an elevated body weight and completed measures on appearance evaluation and depression. Read More

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December 2018

Metabolic Alterations in Celiac Disease Occurring after Following a Gluten-Free Diet.

Digestion 2018 Dec 14:1-7. Epub 2018 Dec 14.

Gastroenterology Unit, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila,

Background And Aim: Many investigations have demonstrated that changes in body weight are frequent in patients with coeliac disease (CD) after a gluten-free diet (GFD); conversely data on the metabolic syndrome (MS) and hepatic steatosis (HS) are still rare. The aim is to evaluate the prevalence of MS and HS in patients with CD, before and after a GFD.

Methods: One hundred eighty-five coeliac adult patients were enrolled in the study. Read More

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December 2018

Relationship between depressive symptom severity and amygdala volume in a large community-based sample.

Psychiatry Res Neuroimaging 2018 Dec 6;283:77-82. Epub 2018 Dec 6.

Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd. MC 8849, Dallas, TX, USA. Electronic address:

Amygdala is an affective processing center that regulates and assigns valence to different emotions and has been implicated in the pathophysiology of mood disorders. This population-based study employed a community sample of 1747 adults to examine relationships between amygdala volume and depressive symptom severity. Neuroimaging data from participants in the Dallas Heart Study were used. Read More

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December 2018

Evodiamine prevents dextran sulfate sodium-induced murine experimental colitis via the regulation of NF-κB and NLRP3 inflammasome.

Biomed Pharmacother 2018 Dec 13;110:786-795. Epub 2018 Dec 13.

College of Veterinary Medicine, Jilin University, Changchun, 130062, People's Republic of China. Electronic address:

Evodiamine (EVO), an extraction from the traditional Chinese medicine Evodia rutaecarpa, has been reported to possess anti-inflammatory, anti-tumor and other pharmacological activities. However, the effectiveness of EVO to relieve dextran sodium sulfate (DSS)-induced ulcerative colitis (UC) has not been evaluated. In this study, the protective effects and mechanisms of EVO on DSS-induced UC mice were investigated. Read More

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December 2018

Chlamydia trachomatis ct143 stimulates secretion of proinflammatory cytokines via activating the p38/MAPK signal pathway in THP-1 cells.

Mol Immunol 2018 Dec 13;105:233-239. Epub 2018 Dec 13.

Department of Immunology, Xiangya School of Medicine, Central South University, Changsha, 410078, China.

Chlamydia trachomatis (Ct) infections can cause bacterial sexually-transmitted and preventable blindness. The Ct infections induced excessive cytokines generation which attributed to pathologic changes in host cells. However, the precise mechanisms of Ct-induced cytokines production are still unclear. Read More

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December 2018

Bioaccumulation and morphological traits in a multi-generation test with two Daphnia species exposed to lead.

Chemosphere 2018 Dec 7;219:636-644. Epub 2018 Dec 7.

Department of Biology & CESAM, University of Aveiro, 3810-193, Portugal.

Anthropic pressure negatively affects natural environments. Lead (Pb) is a non-essential highly toxic metal that is present in aquatic ecosystems. Two daphnid species from two different latitudes, the temperate Daphnia magna and the tropical Daphnia similis were used as test-organisms to evaluate a long-term Pb exposure. Read More

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December 2018

Best practices for teaching pharmacology to undergraduate nursing students: A systematic review of the literature.

Nurse Educ Today 2018 Dec 7;74:15-24. Epub 2018 Dec 7.

Faculty of Health and Social Development, School of Nursing, University of British Columbia, Kelowna, BC, Canada.

Objective: In this systematic review we describe best practices for teaching pharmacology to undergraduate baccalaureate nursing students based on the available evidence. Numerous teaching strategies employed in undergraduate pharmacology courses for nursing students have been summarized and compared for their impact on pharmacology knowledge retention, application of pharmacology theory to practice, and student satisfaction. Future directions for research are discussed. Read More

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December 2018

Physiotherapists implicitly evaluate bending and lifting with a round back as dangerous.

Musculoskelet Sci Pract 2018 Dec 8;39:107-114. Epub 2018 Dec 8.

School of Psychology, Curtin University, Perth, Australia.

Background: Beliefs can be assessed using explicit measures (e.g. questionnaires) that rely on information of which the person is 'aware' and willing to disclose. Read More

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December 2018

How do manual handling advisors and physiotherapists construct their back beliefs, and do safe lifting posture beliefs influence them?

Musculoskelet Sci Pract 2018 Dec 1;39:101-106. Epub 2018 Dec 1.

Centre for Applied Research in Health, University of Huddersfield, HD1 3DH, UK; South West Yorkshire Partnership NHS Foundation Trust, UK.

Background: The Back-Pain Attitudes (Back-PAQ) questionnaire measures back beliefs across 6 domains. Our previous study showed that manual handling advisors (MHAs) have more negative beliefs than physiotherapists (PTs), and those who think straight back lifting is safer than a rounder back have more negative beliefs. However, exactly which domains of the Back-PAQ are most negative is unknown. Read More

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December 2018

Induction of spermiation using Ovaprim™ with topical gill method in the silver rasbora (Rasbora argyrotaenia).

Theriogenology 2018 Dec 8;126:172-176. Epub 2018 Dec 8.

Study Program of Aquaculture, Banyuwangi Campus, Department of Fish Health and Aquaculture, Faculty of Fisheries and Marine, Universitas Airlangga, Indonesia. Electronic address:

The main obstacles on silver rasbora (Rasbora argyrotaenia) culture are having the limited number of broodstock and spawning depending on the season. The purpose of this study was to determine the effect of different dosage of Ovaprim™ induction by topical gill method to silver rasbora spermiation in order to continue the production out of its reproduction season with an optimum dose. A total of 30 male fish with a weight of 7. Read More

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December 2018

A regression model including fetal orbit measurements to predict parturition in Standardbred mares with normal pregnancy.

Theriogenology 2018 Dec 10;126:153-158. Epub 2018 Dec 10.

Department of Veterinary Medical Sciences, University of Bologna, Via Tolara di Sopra 50, 40064, Ozzano Emilia, Bologna, Italy. Electronic address:

In the mare, foaling is a critical unpredictable event due to a wide range of gestational length and the absence of clear signs of impending parturition. To predict foaling, pH, inversion sodium potassium and increase of calcium concentration in mammary secretions are used. The aim of this study was to find how many days are left until parturition knowing mare's age (A) and parity (P) combined with ultrasonographic measurements of the fetal orbit in Standardbred mares with normal pregnancy. Read More

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December 2018

Contraction mode and intensity effects on elbow antagonist muscle co-activation.

J Electromyogr Kinesiol 2018 Dec 8;44:101-107. Epub 2018 Dec 8.

Department of Kinesiology, The University of Toledo, United States.

Introduction: Agonist muscle contraction mode and intensity effects on antagonist co-activation was examined between men and women.

Methods: Fifteen healthy young men (mean ± standard deviation age = 24.9 ± 4. Read More

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December 2018

Gelatin-based Hydrogels as Potential Biomaterials for Colonic Delivery of Oxaliplatin.

Int J Pharm 2018 Dec 13. Epub 2018 Dec 13.

Faculty of Pharmacy, The University of Lahore, Pakistan; International Joint Laboratory for Nuclear Protein Regulation, Henan University, Kaifeng, China.

In present investigation, gelatin-based (AA-co-AMPS) hydrogels were prepared using N, N'-Methylenebisacrylamide (MBA) as a cross-linker and ammonium per sulfate (APS) as an initiator. The successful crosslinking and network formation was confirmed by Fourier transform infrared spectroscopy (FT IR). Differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) investigations proved the higher thermal stability and successful entrapment of oxaliplatin (OXP) in the polymeric network. Read More

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December 2018

A mechanistic account of bodily resonance and implicit bias.

Cognition 2018 Dec 13;184:1-10. Epub 2018 Dec 13.

UCL Institute of Cognitive Neuroscience, London, UK; UCL Queen Square Institute of Neurology, London, UK. Electronic address:

Implicit social biases play a critical role in shaping our attitudes towards other people. Such biases are thought to arise, in part, from a comparison between features of one's own self-image and those of another agent, a process known as 'bodily resonance'. Recent data have demonstrated that implicit bias can be remarkably plastic, being modulated by brief immersive virtual reality experiences that place participants in a virtual body with features of an out-group member. Read More

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December 2018

The comparisons in protective mechanisms and efficiencies among dietary α-lipoic acid, β-glucan and l-carnitine on Nile tilapia infected by Aeromonas hydrophila.

Fish Shellfish Immunol 2018 Dec 13. Epub 2018 Dec 13.

Laboratory of Aquaculture Nutrition and Environmental Health (LANEH), School of Life Sciences, East China Normal University, Shanghai, 200241, PR China. Electronic address:

Dietary α-lipoic acid (LA), β-glucan (Gluc) and l-carnitine (L-Ca) are commonly used additives to promote fish growth and stress resistance in aquaculture production. However their mechanisms and efficiencies in helping fish to resist diseases have not been compared before. In this study, we fed Nile tilapia (Oreochromis niloticus) with diets containing appropriate doses of LA, Gluc and L-Ca for five weeks and further intraperitoneally injected the fish with Aeromonas hydrophila. Read More

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December 2018

Food restriction, but not seasonality, modulates the acute phase response of a neotropical bat.

Comp Biochem Physiol A Mol Integr Physiol 2018 Dec 13. Epub 2018 Dec 13.

Departamento de Zoologia, Instituto de Biociências Universidade Estadual Paulista Julho de Mesquita Filho, Rio Claro, São Paulo, Brazil.

Season and food intake are known to affect immune response of vertebrates yet their effects on metabolic rate have been rarely explored. We tested the effect of season and acute food restriction and their interaction on the energetic cost of immune response activation of a tropical vertebrate, the Seba's short-tailed fruit bat (Carollia perspicillata). We specifically stimulated the acute phase response (APR) with bacterial lipopolysaccharide (LPS) to measure metabolic changes along with changes in body temperature (T), body mass (M), white blood cell counts and the Neutrophil/Lymphocyte ratio (N/L). Read More

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December 2018

Molecular characterization and juvenile hormone-regulated transcription of the vitellogenin receptor in the cabbage beetle Colaphellus bowringi.

Comp Biochem Physiol A Mol Integr Physiol 2018 Dec 13. Epub 2018 Dec 13.

Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. Electronic address:

The vitellogenin receptor (VgR) is highly expressed in the ovaries where it is responsible for vitellogenin (Vg) deposition during oogenesis in insects. Therefore, identifying the VgR of insect pests, and understanding the mechanism regulating its expression, could lead to the development of pest management strategies based on disrupting reproduction. We cloned and identified VgR in the cabbage beetle, Colaphellus bowringi, which is a serious pest of cruciferous vegetables in Asia. Read More

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December 2018

Skim milk powder with high content of Maillard reaction products affect weight gain, organ development and intestinal inflammation in early life in rats.

Food Chem Toxicol 2018 Dec 13. Epub 2018 Dec 13.

Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Sweden; Skane University Hospital, Department of Endocrinology, Lund, Sweden. Electronic address:

Background: The intestinal tract is important for development of immune tolerance and disturbances are suggested to trigger autoimmune disorders. The aim of this study was to explore the effect of Maillard products in skim milk powder obtained after long storage, compared to fresh skim milk powder.

Methods: Young rats were weaned onto a diet based on skim milk powder with high concentration of Maillard products (HM-SM, n = 18) or low (C-SM, n = 18) for one week or four weeks. Read More

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December 2018

Correlation between vertebral bone microstructure and estimated strength in elderly women: An ex-vivo HR-pQCT study of cadaveric spine.

Bone 2018 Dec 13. Epub 2018 Dec 13.

Department of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical Sciences, Japan.

Purpose: A vertebral fracture is the most common complication of osteoporosis, and various factors are involved in its occurrence. The purpose of this study was to investigate the role of trabecular and cortical bone microstructure on vertebral strength using high-resolution peripheral quantitative computed tomography (HR-pQCT).

Methods: Three female cadaveric spines were investigated (average age: 80. Read More

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December 2018

Palatal augmentation prosthesis (PAP) can improve swallowing function for the patients in rehabilitation hospital.

J Prosthodont Res 2018 Dec 12. Epub 2018 Dec 12.

Department of Advanced Prosthodontics, Hiroshima University Graduate School of Biomedical & Health Sciences, Hiroshima, Japan.

Purpose: The aim of this study was to clarify the effects of fitting palatal augmentation prosthesis (PAP) on the swallowing function for the patients in rehabilitation hospital.

Methods: The subjects included 18 elderly hospitalized patients whose body mass index was <18.5kg/m. Read More

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December 2018

Risk factors for admission after shoulder arthroscopy.

J Shoulder Elbow Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Orthopaedic Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Background: Shoulder arthroscopy is a common orthopedic procedure typically performed on an outpatient basis. Occasionally, patients require an unplanned hospital admission. An understanding of the incidence and risk factors for admission after shoulder arthroscopy may assist surgeons in determining which patients may be susceptible to unplanned admission after surgery. Read More

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December 2018

Different patterns of white matter changes after successful surgery of mesial temporal lobe epilepsy.

Neuroimage Clin 2018 Dec 8:101631. Epub 2018 Dec 8.

Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China. Electronic address:

Objectives: To explore the dynamic changes of white matters following anterior temporal lobectomy (ATL) in mesial temporal lobe epilepsy (MTLE) patients who achieved seizure-free at two-year follow-up.

Methods: Diffusion tensor imaging (DTI) was obtained in ten MTLE patients at five serial time points: before surgery, three months, six months, 12 months and 24 months after surgery, as well as in 11 age- and sex-matched healthy controls at one time point. Regions with significant postoperative fractional anisotropy (FA) changes and their dynamic changes were confirmed by comparing all preoperative and postoperative data using Tract-Based Spatial Statistics (TBSS). Read More

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December 2018

Increased usual physical activity is associated with a blunting of the triglyceride response to a high-fat meal.

J Clin Lipidol 2018 Nov 20. Epub 2018 Nov 20.

Program in Personalized and Genomic Medicine, and Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.

Background: Postprandial lipemia (PPL), defined as a prolonged or elevated rise in triglycerides that accompanies fat feeding, is a significant risk factor for coronary heart disease and associated comorbidities. The impact of PPL on coronary heart disease risk is underscored by the preponderance of each day spent in the postprandial state.

Objective: In this study, we evaluated cross-sectionally the association between usual (ie, noninterventional) physical activity and the 6-hour triglyceride response to a standardized high-fat meal. Read More

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November 2018

Sensory trick efficacy in cervical dystonia is linked to processing of neck proprioception.

Parkinsonism Relat Disord 2018 Dec 5. Epub 2018 Dec 5.

Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, UK.

Background: Muscle vibration activates muscle spindles and when applied over posterior neck muscles during stance modulates global body orientation. This is characterised by a tonic forward sway response that is reportedly diminished or absent in patients with idiopathic cervical dystonia.

Objective: To investigating the impact of the sensory trick on vibration-induced postural responses. Read More

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December 2018

Body Mass Index, Change in Weight, Body Weight Variability and Outcomes in Type 2 Diabetes Mellitus (from the ACCORD Trial).

Am J Cardiol 2018 Dec 3. Epub 2018 Dec 3.

Heart and Vascular Center of Excellence, Wake Forest Baptist Health, Winston Salem, North Carolina. Electronic address:

Weight management is highly recommended to patients with diabetes mellitus. However, this prescription is often characterized by weight fluctuations. It remains unclear the effects of weight fluctuations on outcomes in diabetes mellitus. Read More

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December 2018

Insect-inspired neuromorphic computing.

Curr Opin Insect Sci 2018 Dec 21;30:59-66. Epub 2018 Sep 21.

Insect Biology Research Institute, UMR CNRS 7261, University of Tours, Tours 37200, France. Electronic address:

The steady improvement in the performance of computing systems seen for many decades is levelling off as the miniaturization of semiconducting technology approaches the atomic limit, facing severe physical and technological issues. Neuromorphic computing is an emerging solution which makes use of silicon technology in a different way, inline with the computational principles observed in animal nervous systems. In this article, we argue that the nervous systems of insects in particular offer themselves as an ideal starting point for incorporation into realistic neuromorphic systems and review research in developing insect-inspired neuromorphic systems. Read More

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December 2018

Identification and characterization of a novel nuclear structure containing members of the homologous recombination and DNA damage response pathways.

Cancer Genet 2018 Dec 18;228-229:98-109. Epub 2018 Oct 18.

Division of Cancer Biology & Genetics, Cancer Research Institute, Queen's University, Kingston, ON K7L 3N6, Canada; Department of Biochemistry, Queen's University, Kingston, ON K7L 3N6, Canada; Departments of Pathology and Molecular Medicine, and Oncology, Queen's University, Kingston, ON K7L 3N6, Canada. Electronic address:

The human RAD9A protein is required for successful execution of the G2/M DNA damage checkpoint. Along with RAD1 and HUS1, RAD9A exists in a heterotrimeric ring-shaped complex which is necessary for activation of the CHK1 checkpoint kinase. RAD9A is also required for proper localization of both TopBP1 and the Claspin adaptor protein during the DNA damage response. Read More

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December 2018

Physical, psychological and economic burden of two-wheel users after a road traffic injury: Evidence from intensive care units of three EU countries.

J Safety Res 2018 Dec 21;67:155-163. Epub 2018 Oct 21.

Laboratory of Health and Road Safety, Department of Social Work, School of Health and Social Welfare, Technological Educational Institute of Crete, Estavromenos, P.C. 71004 Heraklion, Greece. Electronic address:

Introduction: This study aimed to assess the physical, psychological, and economic burden shouldered by severely injured two-wheel users in three European countries as well as the cost resulting from their hospitalization.

Methods: A total of seven public hospitals were involved in three countries: Greece, Italy, and Germany. Participants enrolled during a 12-month period starting in April 2013. Read More

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December 2018

Medium-chain triglyceride reinforce the hepatic damage caused by fructose intake in mice.

Prostaglandins Leukot Essent Fatty Acids 2019 Jan 10;140:64-71. Epub 2018 Nov 10.

Laboratory of Morphometry, Metabolism and Cardiovascular Diseases, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil.

We aimed to investigate the effects of medium-chain triglyceride oil on the high fructose diet-provoked hepatic abnormalities in mice. We used C57bl/6 mice of 3-months-old divided into four groups for 12 weeks: control (C), control with MCT (C-MCT), fructose (F), and fructose with MCT (F-MCT). We investigated food and water intake, body mass, blood pressure, glucose tolerance, plasma and liver biochemistry, hepatic protein and gene expression. Read More

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January 2019
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Physicochemical surface properties of bacterial cellulose/polymethacrylate nanocomposites: an approach by inverse gas chromatography.

Carbohydr Polym 2019 Feb 31;206:86-93. Epub 2018 Oct 31.

LB3, Faculty of Exact Science and Engineering, University of Madeira, 9000-390 Funchal, Portugal; CIIMAR - Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208, Porto, Portugal. Electronic address:

Nanocomposites of poly(glycidyl methacrylate) and bacterial cellulose (BC), or poly(poly(ethylene glycol) methacrylate) and BC were produced via the in-situ polymerization of methacrylic monomers, inside the BC 3D network. The nanocomposites surface properties were evaluated by inverse gas chromatography (IGC). The dispersive component of surface energy (γ) varied between 35. Read More

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February 2019

Incisional hernia after cystectomy: incidence, risk factors and anthropometric predisposition.

Can J Urol 2018 Dec;25(6):9573-9578

Department of Urology, Hahnemann University Hospital/Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.

Introduction: Postoperative incisional hernias (PIH) are an established complication of abdominal surgery with rates after radical cystectomy (RC) poorly defined. The objective of this analysis is to compare rates and risk factors of PIH after open (ORC) and robotic-assisted (RARC) cystectomy at a tertiary-care referral center.

Materials And Methods: We performed a retrospective review of patients undergoing ORC and RARC from 2000-2015 with pre and postoperative cross-sectional imaging available. Read More

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December 2018

An efficient strategy to estimate thermodynamics and kinetics of G protein-coupled receptor activation using metadynamics and maximum caliber.

J Chem Phys 2018 Dec;149(22):224101

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, New York 10029, USA.

Computational strategies aimed at unveiling the thermodynamic and kinetic properties of G Protein-Coupled Receptor (GPCR) activation require extensive molecular dynamics simulations of the receptor embedded in an explicit lipid-water environment. A possible method for efficiently sampling the conformational space of such a complex system is metadynamics (MetaD) with path collective variables (CVs). Here, we applied well-tempered MetaD with path CVs to one of the few GPCRs for which both inactive and fully active experimental structures are available, the μ-opioid receptor (MOR), and assessed the ability of this enhanced sampling method to estimate the thermodynamic properties of receptor activation in line with those obtained by more computationally expensive adaptive sampling protocols. Read More

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December 2018

Granularity impact on hotspot formation and local chemistry in shocked nanostructured RDX.

Authors:
X Bidault N Pineau

J Chem Phys 2018 Dec;149(22):224703

CEA/DAM/DIF, F-91297 Arpajon, France.

The nanostructuration of energetic materials results in interesting properties. In particular, the detonation of carbon-rich explosives leads to the formation of nanodiamonds, the size of which is linked to the initial size of the explosive nanograins. This correlation could come from the role played by the granularity in the shock properties, especially the local temperature, which could be enhanced when the shock front crosses the various interfaces and nanoporosities of the material. Read More

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December 2018
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