1,293,762 results match your criteria Body & Society[Journal]


Association between neonatal serum bilirubin and childhood obesity in preterm infants.

Pediatr Res 2019 Apr 17. Epub 2019 Apr 17.

Department of Neonatology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

Background: Serum bilirubin levels are inversely associated with obesity in adults. We are interested in whether neonatal jaundice is associated with childhood obesity in preterm infants.

Methods: Data were obtained from the US Collaborative Perinatal Project. Read More

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http://www.nature.com/articles/s41390-019-0399-3
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http://dx.doi.org/10.1038/s41390-019-0399-3DOI Listing
April 2019
2 Reads

Intravitreal Ranibizumab Injection for the Treatment of Retinopathy of Prematurity.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

Objectives: To evaluate the efficacy of a single injection of 0.3 mg of intravitreal ranibizumab for the treatment of retinopathy of prematurity.

Methods: We conducted this retrospective case series study in King Abdul Aziz Medical City, Riyadh, Saudi Arabia. Read More

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http://dx.doi.org/10.1159/000500310DOI Listing
April 2019
1 Read

Sense of Effort and Articulatory Contact Pressure Associated with Talking by Individuals Using Tracheoesophageal Speech.

Authors:
Jeff Searl

Folia Phoniatr Logop 2019 Apr 17:1-10. Epub 2019 Apr 17.

Hearing and Speech Department, University of Kansas Medical Center, Kansas City, Kansas, USA,

Background/aims: The aims of this study were (1) to determine locations of increased effort in the body when talking using tracheoesophageal speech (TES); (2) to compare talking effort for participants using TES and those using laryngeal speech; (3) to compare tongue-palate contact pressure during talking for TES and laryngeal speech; and (4) to assess the relationship between talking effort and articulatory contact pressure (ACP).

Methods: This cohort comparison study included 16 individuals using TES and 10 using laryngeal speech. Participants rated talking effort on a visual analog scale and then rated effort in the lungs, throat, oral cavity, brain (cognitive) and arm/shoulder. Read More

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http://dx.doi.org/10.1159/000496794DOI Listing

The Arginase Pathway in Neonatal Brain Hypoxia-Ischemia.

Dev Neurosci 2019 Apr 17:1-14. Epub 2019 Apr 17.

Department of Pediatrics, University of California San Francisco, San Francisco, California, USA.

Brain damage after hypoxia-ischemia (HI) occurs in an age-dependent manner. Neuroprotective strategies assumed to be effective in adults might have deleterious effects in the immature brain. In order to create effective therapies, the complex pathophysiology of HI in the developing brain requires exploring new mechanisms. Read More

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http://dx.doi.org/10.1159/000496467DOI Listing

Strain-stress relationship and dislocation evolution of W-Cu bilayers from a constructed n-body W-Cu potential.

J Phys Condens Matter 2019 Apr 17. Epub 2019 Apr 17.

State Key Laboratory of Powder Metallurgy, Central South University, Changsha, Hunan, CHINA.

An n-body W-Cu potential is constructed under the framework of the embedded-atom method by means of a proposed function of the cross potential. This W-Cu potential is realistic to reproduce mechanical property and structural stability of WCu solid solutions within the entire composition range, and has better performances than the three W-Cu potentials already published in the literature. Based on this W-Cu potential, molecular dynamics simulation is conducted to reveal the mechanical property and dislocation evolution of the bilayer structure between pure W and W0. Read More

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http://dx.doi.org/10.1088/1361-648X/ab1a8aDOI Listing

ADAM phantom to test 4D medical imaging and dose delivery devices.

Phys Med Biol 2019 Apr 17. Epub 2019 Apr 17.

Agricultural, Food and Forestry System, Universita di Firenze, Florence, ITALY.

Radiotherapy treatment of moving lesions is a challenging task in which different strategies can be used. The clinical implementation of the variety of complex technical solutions pursued to treat cancer, while sparing healthy tissues, requires accurate quality assurance tests and adequate phantoms. The aim of this work is to report on the Anthropomorphic Dynamic breAthing Model (ADAM) and on its applications to test image quality and dose delivery for four-dimensional (4D) techniques used to compensate for breathing-induced tumor motion. Read More

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http://iopscience.iop.org/article/10.1088/1361-6560/ab1a49
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http://dx.doi.org/10.1088/1361-6560/ab1a49DOI Listing
April 2019
1 Read

Considerations for mood and emotion measures in mindfulness-based intervention research.

Curr Opin Psychol 2019 Feb 8;28:279-284. Epub 2019 Feb 8.

Departments of Psychiatry and Medicine, University of Massachusetts Medical School, Worcester, MA 06155, USA.

A large and growing body of work has examined the effects of Mindfulness-Based Interventions (MBI's), such as Mindfulness-Based Stress Reduction and Mindfulness-Based Cognitive Therapy, on emotion-related outcomes, both in mental health settings and general populations. These studies vary widely in the approach to measurement of emotion-related measurements after MBI's. A systematic review of randomized clinical trials of MBIs was conducted with a focus on identifying what emotion-related assays were able to detect changes with MBI's, including scales and instruments (both self-report and clinician-rated) on constructs such as depression, anxiety, emotion regulation, and other mood states. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S2352250X183023
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http://dx.doi.org/10.1016/j.copsyc.2019.02.001DOI Listing
February 2019
1 Read

Tailor-made branch reconstruction by intracranial to intracranial bypass during clipping surgery for middle cerebral artery aneurysms.

World Neurosurg 2019 Apr 14. Epub 2019 Apr 14.

Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan.

Background: In clipping surgery, it is advantageous to dissect an adhered artery from the aneurysmal dome to achieve complete clipping. Bypass surgery is useful to reconstruct an adhered artery when dissection of the artery is technically difficult or risky. Here, we report the effectiveness of tailor-made intracranial (IC)-IC bypass to reconstruct an adhered artery in clipping surgery for middle cerebral artery (MCA) aneurysms. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.04.074DOI Listing

'Acute Flare-Ups' In Patients With, Or At High Risk Of, Knee Osteoarthritis: A Daily Diary Study With Case-Crossover Analysis.

Osteoarthritis Cartilage 2019 Apr 14. Epub 2019 Apr 14.

Clinical Epidemiology, Arthritis Research UK Primary Care Centre, Research Institute for Primary Care & Health Sciences, Keele University, UK. Electronic address:

Objective: To determine the natural history of flare-ups in knee osteoarthritis and their relation to physical exposures.

Design: Adults aged ≥45 years with a recent primary care consultation for knee OA/arthralgia completed a daily pen-and-paper diary for up to 3 months, including questions on average knee pain intensity, pain descriptors, other symptoms, activity interference, and selected physical exposures (prolonged kneeling, squatting, climbing stairs, ladders, and moving/lifting heavy objects). Informed by a systematic review, flare-ups were defined a priori. Read More

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http://dx.doi.org/10.1016/j.joca.2019.04.003DOI Listing

Rhythmic Food Intake Drives Rhythmic Gene Expression More Potently than the Hepatic Circadian Clock in Mice.

Cell Rep 2019 Apr;27(3):649-657.e5

Program of Genetics, Texas A&M University, College Station, TX 77843, USA; Department of Biology, Texas A&M University, College Station, TX 77843, USA. Electronic address:

Every mammalian tissue exhibits daily rhythms in gene expression to control the activation of tissue-specific processes at the most appropriate time of the day. Much of this rhythmic expression is thought to be driven cell autonomously by molecular circadian clocks present throughout the body. By manipulating the daily rhythm of food intake in the mouse, we here show that more than 70% of the cycling mouse liver transcriptome loses rhythmicity under arrhythmic feeding. Read More

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http://dx.doi.org/10.1016/j.celrep.2019.03.064DOI Listing

A difficult foreign body retrieval: when necessity is the mother of invention.

Gastrointest Endosc 2019 Apr 14. Epub 2019 Apr 14.

Gastroenterology and Endoscopy Unit, ARNAS Civico-Di Cristina-Benfratelli Hospital, Palermo, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00165107193159
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http://dx.doi.org/10.1016/j.gie.2019.04.214DOI Listing
April 2019
1 Read

Radiographic Prevalence of Symphysis Pubis Abnormalities and Clinical Outcomes in Patients With Femoroacetabular Impingement Syndrome.

Am J Sports Med 2019 Apr 17:363546519837203. Epub 2019 Apr 17.

Section of Young Adult Hip Surgery, Division of Sports Medicine, Department of Orthopaedic Surgery, Rush Medical College of Rush University, Rush University Medical Center, Chicago, Illinois, USA.

Background: The decreased hip range of motion seen in femoroacetabular impingement syndrome (FAIS) may lead to compensatory increased motion at the symphysis pubis (SP) with resultant increased stress on the joint, which can subsequently lead to osteitis pubis.

Purpose: To quantify the prevalence of SP abnormalities in patients with FAIS through the use of imaging modalities and to compare outcomes based on the presence of SP abnormalities.

Study Design: Cohort study; Level of evidence, 3. Read More

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http://dx.doi.org/10.1177/0363546519837203DOI Listing

Effect of Anti-CD4 Antibody UB-421 on HIV-1 Rebound after Treatment Interruption.

N Engl J Med 2019 04;380(16):1535-1545

From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung - all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD (J.B., K.E.C., T.-W.C.); and the California Department of Public Health, Richmond (C.V.H.).

Background: Administration of a single broadly neutralizing human immunodeficiency virus (HIV)-specific antibody to HIV-infected persons leads to the development of antibody-resistant virus in the absence of antiretroviral therapy (ART). It is possible that monotherapy with UB-421, an antibody that blocks the virus-binding site on human CD4+ T cells, could induce sustained virologic suppression without induction of resistance in HIV-infected persons after analytic treatment interruption.

Methods: We conducted a nonrandomized, open-label, phase 2 clinical study evaluating the safety, pharmacokinetics, and antiviral activity of UB-421 monotherapy in HIV-infected persons undergoing analytic treatment interruption. Read More

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http://www.nejm.org/doi/10.1056/NEJMoa1802264
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http://dx.doi.org/10.1056/NEJMoa1802264DOI Listing
April 2019
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Potential Technologies Review - A hybrid information retrieval framework to accelerate demand-pull innovation in biomedical engineering.

Res Synth Methods 2019 Apr 17. Epub 2019 Apr 17.

Science Management, Institute of Applied Medical Engineering, RWTH Aachen University, Aachen, Germany.

Launching biomedical innovations based on clinical demands instead of translating basic research findings to practice reduces the risk that the results will not fit the clinical routine. To realize this type of innovation, a meta-analysis of the body of research is necessary to reveal demand-matching concepts. However, both the data deluge and the narrow time constraints for innovation make it impossible to perform such reviews manually. Read More

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http://dx.doi.org/10.1002/jrsm.1350DOI Listing

The short-term effect of PRP on chronic pain in knee osteoarthritis.

Agri 2019 Apr;31(2):63-69

Department of Biochemistry, Istanbul Silivri Medicalpark Hospital, Istanbul, Turkey.

Objectives: The administration of platelet-rich plasma (PRP), which increases the release of growth factors targeting cartilage regeneration, is used in an effort to relieve pain in knee osteoarthritis (OA). This study measured the short-term efficacy of PRP on chronic pain in patients with OA of the knee.

Methods: Patients with chronic knee pain and grade 2-4 knee OA based on the Kellgren-Lawrence (K-L) classification were enrolled in the study. Read More

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http://www.agridergisi.com/jvi.aspx?pdir=agri&plng=eng&a
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http://dx.doi.org/10.14744/agri.2019.81489DOI Listing
April 2019
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Effects of Colombian oregano essential oil (Lippia origanoides Kunth) and Eimeria species on broiler production and cecal microbiota.

Poult Sci 2019 Apr 17. Epub 2019 Apr 17.

Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogotá 11001, Colombia.

The gut microbiota has an important effect on poultry health and production. The aim of this study was to evaluate the effect of Colombian oregano (COO), Lippia origanoides Kunth, essential oil supplementation on broiler chicken performance and their cecal bacterial microbiome by 16S-based sequencing. Essential oil was extracted by steam distillation and analyzed by Gas chromatography/mass spectrometry. Read More

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http://dx.doi.org/10.3382/ps/pez193DOI Listing

Effect of low protein diets supplemented with free amino acids on growth performance, slaughter yield, litter quality, and footpad lesions of male broilers.

Poult Sci 2019 Apr 17. Epub 2019 Apr 17.

Wageningen Livestock Research, 6700 AH Wageningen, the Netherlands.

A study with 884 Ross 308 male broilers, housed in 68 floor pens (0.75 m2) from 0 to 35 days of age was conducted to evaluate the effects of low crude protein (CP) diets, with partial replacement of soybean meal by free amino acids (AA), on performance, slaughter yields, litter quality and footpad lesions. During the first 11 d, all broilers received the same control starter diet (216 g/kg CP, 11. Read More

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http://dx.doi.org/10.3382/ps/pez229DOI Listing

Effects of water supplementation of an organic acid-trace mineral complex on production and slaughter parameters, intestinal histomorphology, and macronutrient digestibility in growing ostriches.

Poult Sci 2019 Apr 17. Epub 2019 Apr 17.

Department of Research and Development, Sodour Ahrar Shargh Company, Tehran 14159-4-4341, Iran.

An experiment was conducted to study the effect of water supplementation of organic acid-chelated trace minerals (OTM) on production traits, carcass characteristics, intestinal histomorphology, and nutrient digestibility in African ostrich chicks from 8 to 12 mo of age. A total of 20 growing ostriches, with almost similar body weight (73.4 to 75. Read More

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https://academic.oup.com/ps/advance-article/doi/10.3382/ps/p
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http://dx.doi.org/10.3382/ps/pez221DOI Listing
April 2019
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Effects of dietary energy and protein content and lipid source on growth performance and carcass traits in Pekin ducks.

Poult Sci 2019 Apr 17. Epub 2019 Apr 17.

State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China.

The present study was conducted to determine the impact of dietary energy and protein concentrations and lipid sources on growth performance and carcass traits of Pekin ducks. In Exp. 1, 15-day-old ducks (6 replicate pens, 60 ducks/pen) were randomly assigned to 4 dietary treatments with different metabolizable energy (ME) and crude protein (CP) concentrations (2,850 kcal/kg and 16%, 2,950 kcal/kg and 16. Read More

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http://dx.doi.org/10.3382/ps/pez217DOI Listing

The proportion of alveolar type 1 cells decreases in murine hypoplastic congenital diaphragmatic hernia lungs.

PLoS One 2019 17;14(4):e0214793. Epub 2019 Apr 17.

Department of Development and Regeneration, Division Organ Systems, KU Leuven, Leuven, Belgium.

Background: Pulmonary hypoplasia, characterized by incomplete alveolar development, remains a major cause of mortality and morbidity in congenital diaphragmatic hernia. Recently demonstrated to differentiate from a common bipotent progenitor during development, the two cell types that line the alveoli type 1 and type 2 alveolar cells have shown to alter their relative ratio in congenital diaphragmatic hernia lungs.

Objective: We used the nitrofen/bisdiamine mouse model to induce congenital diaphragmatic hernia and accurately assess the status of alveolar epithelial cell differentiation in relation to the common bipotent progenitors. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214793PLOS

Repeatability of brown adipose tissue measurements on FDG PET/CT following a simple cooling procedure for BAT activation.

PLoS One 2019 17;14(4):e0214765. Epub 2019 Apr 17.

Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri, United States of America.

Brown Adipose Tissue (BAT) is present in a significant number of adult humans and can be activated by exposure to cold. Measurement of active BAT presence, activity, and volume are desirable for determining the efficacy of potential treatments intended to activate BAT. The repeatability of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) measurements of BAT presence, activity, and volume under controlled conditions has not been extensively studied. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214765PLOS

Spondylosis deformans as an indicator of transport activities in archaeological dogs: A systematic evaluation of current methods for assessing archaeological specimens.

PLoS One 2019 17;14(4):e0214575. Epub 2019 Apr 17.

Department of Anthropology, University of Alberta, Edmonton, Alberta, Canada.

Over the past several decades archaeologists have used the spinal pathology spondylosis deformans as an indicator that archaeological dogs were used to pull or carry loads. This interpretive approach is largely based upon observations of prehistoric dog remains and archaeologist's interpretations of veterinary literature on recent sled dogs and other draft animals. However, no comparative large-scale studies of the occurrence of spondylosis deformans in wild canids, transport dogs, and dogs never involved in pulling or carrying loads have been published. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214575PLOS

Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease.

PLoS Negl Trop Dis 2019 Apr 17;13(4):e0007324. Epub 2019 Apr 17.

Laboratory of Molecular Immunopathology, Department of Clinical Pathology, Federal University of Paraná, Curitiba, Brazil.

Chagas Disease (CD) is an anthropozoonosis caused by Trypanosoma cruzi. With complex pathophysiology and variable clinical presentation, CD outcome can be influenced by parasite persistence and the host immune response. Complement activation is one of the primary defense mechanisms against pathogens, which can be initiated via pathogen recognition by pattern recognition molecules (PRMs). Read More

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http://dx.plos.org/10.1371/journal.pntd.0007324
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http://dx.doi.org/10.1371/journal.pntd.0007324DOI Listing
April 2019
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Putative parapoxvirus-associated foot disease in the endangered huemul deer (Hippocamelus bisulcus) in Bernardo O'Higgins National Park, Chile.

PLoS One 2019 17;14(4):e0213667. Epub 2019 Apr 17.

One Health Institute, School of Veterinary Medicine, University of California, Davis, CA, United States of America.

The huemul (Hippocamelus bisulcus) is an endangered cervid endemic to southern Argentina and Chile. Here we report foot lesions in 24 huemul from Bernardo O'Higgins National Park, Chile, between 2005 and 2010. Affected deer displayed variably severe clinical signs, including lameness and soft tissue swelling of the limbs proximal to the hoof or in the interdigital space, ulceration of the swollen tissues, and some developed severe proliferative tissue changes that caused various types of abnormal wear, entrapment, and/or displacement of the hooves and/or dewclaws. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213667PLOS

Vimentin is required for normal accumulation of body fat.

Biol Chem 2019 Apr 1. Epub 2019 Apr 1.

Laboratory of Astrocyte Biology and CNS Regeneration, Center for Brain Repair, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Box 440, S-40530 Gothenburg, Sweden.

Intermediate filaments (nanofilaments) have many functions, especially in response to cellular stress. Mice lacking vimentin (Vim-/-) display phenotypes reflecting reduced levels of cell activation and ability to counteract stress, e.g. Read More

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http://dx.doi.org/10.1515/hsz-2019-0170DOI Listing

The Prevalence and Functional Impact of Chronic Edema and Lymphedema in Japan: LIMPRINT Study.

Lymphat Res Biol 2019 Apr;17(2):195-201

2 Department of Gerontological Nursing/Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

This was a part of LIMPRINT (Lymphoedema IMpact and PRevalence-INTernational), an international study aimed at capturing the size and impact of lymphedema and chronic edema in different countries and health services across the world. The purpose of this study was to clarify the prevalence and the impact of chronic edema in Japan. This was a two-phase facility-based study to determine the prevalence and functional impact of chronic edema in the adult population in Japan between 2014 and 2015. Read More

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https://www.liebertpub.com/doi/10.1089/lrb.2018.0080
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http://dx.doi.org/10.1089/lrb.2018.0080DOI Listing
April 2019
1 Read

Lymphedema Impact and Prevalence International Study: The Canadian Data.

Lymphat Res Biol 2019 Apr;17(2):178-186

2 Parkwood Institute Research, St. Joseph's Health Care London, Lawson Health Research Institute, London, Canada.

Chronic edema/lymphedema is defined as edema present for more than 3 months. It is underrecognized and undertreated. The International Lymphedema Framework developed an international study, Lymphedema Impact and Prevalence International (LIMPRINT), to estimate the prevalence and impact of chronic edema in heterogeneous populations. Read More

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http://dx.doi.org/10.1089/lrb.2019.0014DOI Listing

Galvanic vestibular stimulation: from basic concepts to clinical applications.

J Neurophysiol 2019 Apr 17. Epub 2019 Apr 17.

Department Biology II, Ludwig-Maximilians-University Munich, Germany.

Galvanic vestibular stimulation (GVS) plays an important role in the quest to understand sensory signal processing in the vestibular system under normal and pathological conditions. It has become a highly relevant tool to probe neuronal computations and to assist in the differentiation and treatment of vestibular syndromes. Following its accidental discovery, GVS became a diagnostic tool that generates eye movements in the absence of head/body motion. Read More

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https://www.physiology.org/doi/10.1152/jn.00035.2019
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http://dx.doi.org/10.1152/jn.00035.2019DOI Listing
April 2019
1 Read

Concentration and Prevalence of Aflatoxin M in Human Breast Milk in Iran: Systematic Review, Meta-Analysis, and Carcinogenic Risk Assessment: A Review.

J Food Prot 2019 Apr 15:785-795. Epub 2019 Apr 15.

8 Department of Food Science, Faculty of Food Engineering, University of Campinas, Rua Monteiro Lobato 80, 13083-862 Campinas, São Paulo, Brazil (ORCID: https://orcid.org/0000-0001-5769-0004 ).

This meta-analysis was designed to review the published reports regarding the concentration and/or prevalence of aflatoxin M (AFM) in human breast milk in Iran. The carcinogenic risk for Iranian infants consuming this milk was estimated with the hazard index. The PubMed and Scopus databases and the Scientific Information Database were screened for relevant studies between 1995 and 2017, and 11 of the 112 collected studies were included in the systematic review and meta-analysis. Read More

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http://dx.doi.org/10.4315/0362-028X.JFP-18-367DOI Listing

Long-term survivors of cardiac arrest: A narrative inquiry.

Eur J Cardiovasc Nurs 2019 Apr 17:1474515119844717. Epub 2019 Apr 17.

University of Newcastle, Port Macquarie, Australia.

Background: Despite extensive knowledge and research in cardiac health there is limited understanding in how a cardiac arrest influences the life of long-term survivors.

Objective: The aim of this study was to explore how long-term survivors of a cardiac arrest adjusted to their new reality, expressed in their re-storied narratives.

Methods: Seven individuals surviving a cardiac arrest 5-26 years ago were interviewed through in-depth conversations over a six-month period. Read More

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http://dx.doi.org/10.1177/1474515119844717DOI Listing

International comparisons of autism spectrum disorder behaviors in preschoolers rated by parents and caregivers/teachers.

Autism 2019 Apr 17:1362361319839151. Epub 2019 Apr 17.

2 University of Vermont, USA.

This study tested international similarities and differences in scores on a scale comprising 12 items identified by international mental health experts as being very consistent with the Diagnostic and Statistical Manual of Mental Disorders (5th ed.) category of autism spectrum disorder. Participants were 19,850 preschoolers in 24 societies rated by parents on the Child Behavior Checklist for Ages 1½-5; 10,521 preschoolers from 15 societies rated by caregivers/teachers on the Caregiver-Teacher Report Form, and 7380 children from 13 societies rated by both types of informant. Read More

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http://dx.doi.org/10.1177/1362361319839151DOI Listing

The Human Lung Cell Atlas - A high-resolution reference map of the human lung in health and disease.

Am J Respir Cell Mol Biol 2019 Apr 17. Epub 2019 Apr 17.

University of Groningen, University Medical Center Groningen, Pathology and Medical Biology, Groningen, Netherlands.

Lung disease accounts for every sixth death globally. Profiling the molecular state of all lung cell types in health and disease is currently revolutionizing the identification of disease mechanisms and will aid the design of novel diagnostic and personalized therapeutic regimens. Recent progress in high-throughput techniques for single-cell genomic and transcriptomic analyses has opened up new possibilities to study individual cells within a tissue, classify these into cell types, and characterize variations in their molecular profiles as a function of genetics, environment, cell-cell interactions, developmental processes, ageing or disease. Read More

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https://www.atsjournals.org/doi/10.1165/rcmb.2018-0416TR
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http://dx.doi.org/10.1165/rcmb.2018-0416TRDOI Listing
April 2019
1 Read

Reduced Left Ventricular Diastolic Function in Women with Post-Traumatic Stress Disorder.

Am J Physiol Regul Integr Comp Physiol 2019 Apr 17. Epub 2019 Apr 17.

Cardiology Division, Internal Medicine, UT Southwestern Medical Center, United States.

Women are 2-3 times more likely to develop post-traumatic stress disorder (PTSD) compared with men after exposure to a major trauma, and PTSD is associated with increased risk for cardiovascular disease in later life. The underlying mechanisms are unclear, but alterations in cardiac function may be involved. We hypothesized that women with PTSD have reduced left ventricular (LV) diastolic function. Read More

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https://www.physiology.org/doi/10.1152/ajpregu.00002.2019
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http://dx.doi.org/10.1152/ajpregu.00002.2019DOI Listing
April 2019
1 Read

[Menopausal hormone therapy. Effects on bone and body composition].

Rev Med Suisse 2019 Apr;15(647):836-839

Centre des maladies osseuses, Département de l'appareil locomoteur, CHUV, 1011 Lausanne.

Changes occurring at menopause can be mitigated by prescribing menopausal hormone replacement therapy (HRT). Recent publications from the CoLaus/OsteoLaus cohorts provide important insights into the effects of HRT and after its discontinuation on bone and body composition. HRT has a beneficial effect on bone mineral density, bone microarchitecture and fracture prevention. Read More

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April 2019
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The effects of parathyroid hormone-related peptide on cardiac angiogenesis, apoptosis, and function in mice with myocardial infarction.

J Cell Biochem 2019 Apr 17. Epub 2019 Apr 17.

Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

It is known that parathyroid hormone-related peptide (PTHrP) contains a nuclear localization sequence (NLS, 87-107), which, together with its C-terminus (107-139), has been shown to positively regulate vascular smooth muscle cell (VSMCs) proliferation and vascular neointima formation, and inhibit cellular apoptosis. The role of PTHrP in ischemic cardiac diseases remains unclear. In this study, we attempted to determine whether PTHrP 87 to 139 can play a role in promoting cardiac function via enhancing angiogenesis after myocardial infarction (MI) occurred. Read More

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http://dx.doi.org/10.1002/jcb.28735DOI Listing

Radiosynthesis, radiochemical, and biological characterization of Lu-labeled diethylenetriamine penta-acetic acid.

J Cell Biochem 2019 Apr 17. Epub 2019 Apr 17.

Department of Medical Sciences, Pakistan Institute of Engineering and Applied Sciences, Islamabad, Pakistan.

Diethylenetriamine penta-acetic acid (DTPA), when complexed with a gamma (γ)-emitter radioisotope like Tc, is used for renal function diagnosis and many other diagnostic applications. The main aim of this study was to develop a novel and versatile single-step methodology for the synthesis of a new Lu-labeled radiopharmaceutical with high radiochemical yield, which can be used for diagnostic purposes and therapeutic purposes also. The single and well-defined Lu-DTPA complex was radiochemically characterized by paper chromatography, thin-layer chromatography, high-performance liquid chromatography, and electrophoresis techniques. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.28712
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http://dx.doi.org/10.1002/jcb.28712DOI Listing
April 2019
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GLP-1 induces alpha cell proliferation and overrides leptin suppression induced by negative energy balance in vagotomized rats.

J Cell Biochem 2019 Apr 17. Epub 2019 Apr 17.

Endocrine, Cardiovascular & Metabolic Research, Unit for Multidisciplinary Research in Biomedicine (UMIB), University of Porto, Porto, Portugal.

Glucagon-like peptide-1 (GLP-1) influences energy balance by exerting effects on food intake and glucose metabolism, through mechanisms that are partially dependent on the vagal pathway. The aim of this study was to characterize the effects of chronic GLP-1 stimulation on energy homeostasis and glucose metabolism in the absence of vagal innervation Truncal vagotomized (VGX) and sham operated rats (SHAM) received an intraperitoneal GLP-1 infusion (3.5 pmol/kg/min) trough mini-osmotic pumps. Read More

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http://dx.doi.org/10.1002/jcb.28719DOI Listing

Fabella prevalence rate increases over 150 years, and rates of other sesamoid bones remain constant: a systematic review.

J Anat 2019 Apr 17. Epub 2019 Apr 17.

Department of Bioengineering, Imperial College London, London, UK.

The fabella is a sesamoid bone located behind the lateral femoral condyle. It is common in non-human mammals, but the prevalence rates in humans vary from 3 to 87%. Here, we calculate the prevalence of the fabella in a Korean population and investigate possible temporal shifts in prevalence rate. Read More

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http://dx.doi.org/10.1111/joa.12994DOI Listing

Gut microbiome interventions in human health and diseases.

Med Res Rev 2019 Apr 17. Epub 2019 Apr 17.

Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan, Hubei, China.

Ongoing studies have determined that the gut microbiota is a major factor influencing both health and disease. Host genetic factors and environmental factors contribute to differences in gut microbiota composition and function. Intestinal dysbiosis is a cause or a contributory cause for diseases in multiple body systems, ranging from the digestive system to the immune, cardiovascular, respiratory, and even nervous system. Read More

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http://dx.doi.org/10.1002/med.21584DOI Listing

Genetic risk, body mass index, and weight control behaviors: Unlocking the triad.

Int J Eat Disord 2019 Apr 17. Epub 2019 Apr 17.

Department of Psychiatry, University of California, San Francisco, San Francisco, California.

Background: The relationship between genetic risk for body mass index (BMI) and weight control behaviors remains unknown. The objectives of this study were to determine the association between genetic risk for BMI and weight control behaviors in young adults, and to examine actual measured BMI as a potential mediator variable.

Method: We analyzed data from three data collection waves of the National Longitudinal Study of Adolescent to Adult Health. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/eat.23083
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http://dx.doi.org/10.1002/eat.23083DOI Listing
April 2019
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A curious association of chronic homeopathic arsenic ingestion with nonspecific symptoms in a Swiss teenager.

Authors:
Sergio U Dani

Swiss Med Wkly 2019 Apr 17;149:w20071. Epub 2019 Apr 17.

Medawar Institute for Medical and Environmental Research, Acangau Foundation, Paracatu, MG, Brazil, and PizolCare Praxis Sargans, Switzerland.

Arsenic is a toxicant that has no dose threshold below which exposures are not harmful. Here I report a curious association of chronic homeopathic arsenic ingestion with nonspecific symptoms in a Swiss teenager. For about 4 years she had taken globules of a freely purchasable homeopathic remedy containing inorganic arsenic (iAs), infinitesimally diluted to D6 (average arsenic content per single globule: 0. Read More

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https://doi.emh.ch/smw.2019.20071
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http://dx.doi.org/10.4414/smw.2019.20071DOI Listing
April 2019
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Predictors of quality of life in Brazilian medical students: a systematic review and meta-analysis.

Braz J Psychiatry 2019 Apr 15. Epub 2019 Apr 15.

Departamento e Instituto de Psiquiatria, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, Brazil.

Objective: To examine predictors associated with quality of life (QoL) in Brazilian medical students.

Methods: PubMed, PsycINFO, EMBASE, LILACS, and Google Scholar were searched for research articles in English or Portuguese published through August 2018. Observational studies that measured QoL with standard instruments were selected. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/1516-4446-2018-0116DOI Listing
April 2019
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Uremic neuropathy: an overview of the current literature.

Rev Assoc Med Bras (1992) 2019 Mar 11;65(3):469-474. Epub 2019 Apr 11.

Department of Integrated Clinical Discussions, ABC Medical School, Santo André, SP, Brasil.

Introduction: Peripheral neuropathy is a disorder that affects the cell body, axon or myelin of motor or peripheral sensory neurons and occurs in 60-100% of patients who are submitted to dialysis due to chronic kidney disease. Uremic neuropathy (UN) is attributed to the accumulation of organic waste, evident in patients with reduced glomerular filtration rate.

Objectives: This review aims to make clinical characteristics of uremic neuropathy evident enabling early diagnosis and treatment. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/1806-9282.65.3.469DOI Listing
March 2019
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The positive impact of physical activity on the reduction of anxiety scores: a pilot study.

Rev Assoc Med Bras (1992) 2019 Mar 11;65(3):434-440. Epub 2019 Apr 11.

Professor of the Medical Program of the Metropolitan Institute of Higher Education/IMES - Univaço, Ipatinga, Minas Gerais, Brasil.

Objectives: To compare anxiety scores between physical activity practitioners and sedentary, men and women and to relate them to physical activity frequency and age.

Methods: In this cross-sectional study, a sample of 256 regular aerobic physical activity practitioners was compared to a sample of 256 sedentary individuals (control group). Anxiety scores were quantified by Anxiety Inventory Spielberger State-Trait (STAI). Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/1806-9282.65.3.434DOI Listing
March 2019
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Sleep disorders in polycystic ovary syndrome: influence of obesity and hyperandrogenism.

Rev Assoc Med Bras (1992) 2019 Mar 11;65(3):375-383. Epub 2019 Apr 11.

Department of Psychobiology, Federal University of Sao Paulo, Sao Paulo, SP, Brasil.

Objective: This study aims to evaluate the sleep of subjects with polycystic ovary syndrome (PCOS), with and without hyperandrogenism, in comparison with a healthy control group and examine the effects of hyperandrogenism and obesity on sleep parameters.

Methods: A total of 44 volunteers were recruited to participate in the study. Clinical, biochemical and polysomnographic parameters were used to diagnose PCOS and hyperandrogenism. Read More

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http://dx.doi.org/10.1590/1806-9282.65.3.375DOI Listing
March 2019
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Influences of dietary crude protein and stocking density on growth performance and body measurements of ostrich chicks.

An Acad Bras Cienc 2019 8;91(1):e20180479. Epub 2019 Apr 8.

Nutrition and Clinical Nutrition Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt.

Thirty-six African Black ostrich chicks were used to investigate the effects of dietary crude protein (CP) levels (180, 210 and 240 g/kg), stocking density (4.5 and 3 m2/bird) and their interactions. A factorial arrangement was used to examine the impact of treatments on growth performance and body measurements of ostrich chicks during 2 to 10 weeks of the age. Read More

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http://dx.doi.org/10.1590/0001-3765201920180479DOI Listing

Metacercariae of Strigeidae Parasitizing Amphibians of the Chaco Region in Argentina.

An Acad Bras Cienc 2019 8;91(1):e20180044. Epub 2019 Apr 8.

Consejo Nacional de Investigaciones Científicas y Técnicas/CONICET, Centro de Ecología Aplicada del Litoral/CECOAL, W 3400 AMD, Corrientes, Argentina.

The goal of the present study was to analyze the metacercariae found in adult amphibians collected in the Argentinean Chaco region. A total of 194 frogs, Leptodactylus chaquensis, Leptodactylus latinasus, and Lepidobatrachus laevis was examined for digeneans. Three different larval trematodes of the genus Strigea (Digenea, Strigeidae) were found infecting the liver, mesentery, body cavity, and muscle of frogs. Read More

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http://dx.doi.org/10.1590/0001-3765201920180044DOI Listing

Ecological aspects of natural populations of Hyalella pampeana (Crustacea, Amphipoda, Hyalellidae) from the Natural Reserve Island of Martín García (Río de La Plata, Argentina).

An Acad Bras Cienc 2019 8;91(1):e20170928. Epub 2019 Apr 8.

Departamento de Biología, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata/FCEyN, UNMdP, Funes St. 3350, 7600 Mar del Plata, Argentina.

Freshwater amphipods of the genus Hyalella have a great importance in aquatic ecosystems due to their role in matter and energy cycling and its utilization as bioindicators of environmental health. The aim of this work was to analyze relevant population parameters of Hyalellapampeana, such as population density and structure, individual body size, sex ratio, fecundity and recruitment, and to study the possible relation of these parameters to variations in environmental variables. Samples were taken monthly during a one-year period (2006) at three small ponds in the Natural Reserve Island of Martín García, Argentina. Read More

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http://dx.doi.org/10.1590/0001-3765201920170928DOI Listing

Reproductive aspects of the semi-aquatic snake Erythrolamprus miliaris (Dipsadidae: Xenodontini) in the state of Rio de Janeiro, southeastern Brazil.

An Acad Bras Cienc 2019 8;91(1):e20170657. Epub 2019 Apr 8.

Departamento de Zoologia, Instituto de Biociências, Universidade Federal do Estado do Rio de Janeiro, Avenida Pasteur, 458, Urca, 22290-255 Rio de Janeiro, RJ, Brazil.

We analyzed some aspects of reproduction and sexual dimorphism of the semi-aquatic dipsadid snake Erythrolamprus miliaris in the state of Rio de Janeiro, southeastern Brazil. We detected sexual dimorphism in body size (snout-vent length), with females averaging larger than males, but no sexual dimorphism in the relative length of the tail. Oviductal eggs and secondary follicles were found in all seasons, suggesting that female reproductive cycles are continuous, in spite of the tropical seasonal climate in the region. Read More

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http://dx.doi.org/10.1590/0001-3765201920170657DOI Listing
April 2019
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Experiences of transgender women/transvestites with access to health services: progress, limits, and tensions.

Cad Saude Publica 2019 8;35(4):e00111318. Epub 2019 Apr 8.

Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de de Janeiro, Brasil.

Given both the changes in sexual customs, norms and policies and the persistent patterns in Brazil, the article analyzes the experiences of transgender women/transvestites with access to health services and discusses sexual/gender discrimination and their demands for gender transition and AIDS prevention services. The study involved interviews with nine transgender women/transvestites 23-45 years of age from low-income strata in the Baixada Fluminense region of Greater Metropolitan Rio de Janeiro, Brazil, in 2016 and observation of contexts of prostitution and sociability. Compared to the violence experienced years previously, the narratives of transgender women/transvestites highlight important social strides. Read More

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http://dx.doi.org/10.1590/0102-311X00111318DOI Listing
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