786 results match your criteria Bmj Supportive & Palliative Care[Journal]


Meaning in life and quality of life: palliative care patients versus the general population.

BMJ Support Palliat Care 2020 Jul 6. Epub 2020 Jul 6.

Palliative and Supportive Care Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Background And Objectives: Meaning in life (MIL) represent a key topic in palliative care. The aims of this study were to explore (1) the differences in perceived MIL and in the meaning-relevant life areas between a representative sample of the Swiss population and palliative care patients, and (2) to what extent MIL can be considered as a significant predictor of quality of life (QOL).

Methods: A cross-sectional study was conducted separately for the patients (face-to-face interviews) and the general population (telephone survey). Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002211DOI Listing

Fan therapy for cough: case report and literature review.

BMJ Support Palliat Care 2020 Jul 6. Epub 2020 Jul 6.

Palliative Care, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

This case report describes the care of a 59-year-old woman with metastatic small cell lung cancer and chronic obstructive pulmonary disease who was highly symptomatic with an intractable cough. The patient reported a subjective benefit from a table fan. The authors observed an objective improvement with a marked reduction in cough frequency when the fan was in use. Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002363DOI Listing

Lemierre's syndrome in an intravenous drug user.

BMJ Case Rep 2020 Jul 5;13(7). Epub 2020 Jul 5.

Department of Internal Medicine, Wright Center for Graduate Medical Education, Scranton, Pennsylvania, USA

A 29-year-old Dominican man with a history of intravenous heroin use and hepatitis C presented with a 5-day history of fever, dyspnoea, haemoptysis, pleuritic chest pain, abdominal pain, haematochezia and haematemesis. Initial physical examination was significant for scleral icterus, generalised abdominal tenderness to palpation, melaena and blood-tinged sputum. Blood cultures grew species. Read More

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http://dx.doi.org/10.1136/bcr-2020-235390DOI Listing

Against the odds: unlikely COVID-19 recovery.

BMJ Support Palliat Care 2020 Jul 3. Epub 2020 Jul 3.

Royal United Hospital Bath NHS Trust, Bath, Bath and North East Somerset, UK.

Background: We present a 67-year-old male, with palliative hypopharyngeal squamous cell carcinoma, who contracted COVID-19 infection while in hospital. Cancer diagnosis, among other clinical features, increases the risk of poor outcome of COVID-19 infection. A recently validated risk calculator (COVID-GRAM) can help to guide prognosis. Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002477DOI Listing

Viral and bacterial coinfection of the respiratory tract in a 10-month-old child.

BMJ Case Rep 2020 Jul 1;13(7). Epub 2020 Jul 1.

Consultant, Department of Paediatrics and Neonates, North Manchester General Hospital, Manchester, England, UK.

A 10-month-old child, immunised appropriately for age, presented with a history of cough, vomiting, diarrhoea, increased work of breathing and eye redness for 1 week. She was treated for suspected bronchiolitis with supportive oxygen and hypertonic saline nebulisation. In view of continuing fever spikes and persistent oxygen requirement, she was evaluated further. Read More

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http://dx.doi.org/10.1136/bcr-2020-235295DOI Listing

Evaluation of a learning collaborative to advance team-based care in Federally Qualified Health Centers.

BMJ Open Qual 2020 Jul;9(3)

Weitzman Institute, Community Health Center Inc, Middletown, Connecticut, USA.

Practising team-based primary care allows Federally Qualified Health Centers (FQHC) in the USA to be accredited as patient-centred medical homes, positioning them for value-based models of shared savings in healthcare costs. Team-based care (TBC) involves redesign of staff roles and care delivery processes to improve efficiency and effectiveness, which requires a systematic and supportive approach to practice change over time. Thirteen FQHC primary care teams participated in an 8-month learning collaborative with a goal of providing teams with the knowledge, skills and coaching support needed to advance TBC in their organisations. Read More

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http://dx.doi.org/10.1136/bmjoq-2019-000794DOI Listing

4-month-old boy coinfected with COVID-19 and adenovirus.

BMJ Case Rep 2020 Jun 30;13(6). Epub 2020 Jun 30.

Pediatrics, Rush University Medical Center, Chicago, Illinois, United States.

A 4-month-old boy with a history of muscular ventricular septal defect and atopic dermatitis presented with decreased oral intake, loose stools, stuffy nose, mild cough and diaphoresis. The patient had an in-home exposure to COVID-19. The initial respiratory pathogen panel was positive for adenovirus, consistent with his symptoms. Read More

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http://dx.doi.org/10.1136/bcr-2020-236264DOI Listing

Parecoxib for opioid-induced hyperalgesia.

BMJ Support Palliat Care 2020 Jun 29. Epub 2020 Jun 29.

Department of Pharmacy, The Christie NHS Foundation Trust, Manchester, UK.

This paper describes the case report of a patient admitted to hospital with severe and complex pain and subacute bowel obstruction, who failed to respond to multiple analgesic regimens including ketamine burst and opioid rotation, and was subsequently successfully managed with a parecoxib infusion. Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002290DOI Listing

Colorectal cancer survivors' quality of life: a qualitative study of unmet need.

BMJ Support Palliat Care 2020 Jun 29. Epub 2020 Jun 29.

School of Nursing and Midwifery, Trinity College Dublin, Dublin, Dublin 2, Ireland.

Objective: Cancer survivors' perceptions of healthcare have been identified as a predictor of quality of life (QoL) outcomes. This study aims to explore colorectal cancer (CRC) survivors' perceptions of how cancer-related healthcare affects their QoL.

Methods: Semistructured interviews were conducted with 22 CRC survivors receiving follow-up care between 1 and 5 years post diagnosis. Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002190DOI Listing

Descriptive study of workplace demand, control and bullying among migrant and Australian-born workers by gender: does workplace support make a difference?

BMJ Open 2020 Jun 28;10(6):e033652. Epub 2020 Jun 28.

Preventive Medicine and Public Health Area, University of Alicante, Alicante, Alicante, Spain.

Objective: The objective of this study is to examine the relationship between bullying in migrants and Australians and types of workplace Iso-strain, by gender.

Design And Setting: Two descriptive cross-sectional surveys of the Australian working population.

Participants: Australian-born workers of Caucasian ancestry (n=1051, participant response rate=87. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-033652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322333PMC

The ACS-TQIP palliative care guidelines at two level I trauma centres: a prospective study of patient and caregiver satisfaction.

BMJ Support Palliat Care 2020 Jun 24. Epub 2020 Jun 24.

Trauma Research Department, St Anthony Hospital and Medical Campus, Lakewood, Colorado, USA

Objectives: To measure trauma patient and caregiver satisfaction before and after implementation of standardised palliative care (PC) guidelines.

Methods: Prospective pre-post study at two level-I trauma centres. PC satisfaction surveys were administered prior to discharge for consented trauma patients (Family Satisfaction with Advanced Cancer Scale, Patient (FAMCARE-P13) survey)≥55 years, and their caregivers (FAMCARE survey), from 1 November 2016 to 30 November 2018. Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002229DOI Listing

Mindful breathing for suffering.

BMJ Support Palliat Care 2020 Jun 24. Epub 2020 Jun 24.

Department of Medicine, University of Malaya, Kuala Lumpur, Wilayah Persekutuan, Malaysia

We present a case of a 64-year-old woman with stage 1 breast cancer. She underwent a modified radical mastectomy, followed by chemotherapy. She reported physical and psychosocial suffering due to her disease and treatment. Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002373DOI Listing

Facilitators and barriers to general practitioner and general practice nurse participation in end-of-life care: systematic review.

BMJ Support Palliat Care 2020 Jun 19. Epub 2020 Jun 19.

Primary Care Clinical Unit, The University of Queensland Faculty of Medicine, Herston, Queensland, Australia

Background: General practitioners (GPs) and general practice nurses (GPNs) face increasing demands to provide palliative care (PC) or end-of-life care (EoLC) as the population ages. To enhance primary EoLC, the facilitators and barriers to their provision need to be understood.

Objective: To provide a comprehensive description of the facilitators and barriers to GP and GPN provision of PC or EoLC. Read More

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http://dx.doi.org/10.1136/bmjspcare-2019-002109DOI Listing

Anticipatory prescribing in community end-of-life care in the UK and Ireland during the COVID-19 pandemic: online survey.

BMJ Support Palliat Care 2020 Jun 16. Epub 2020 Jun 16.

Department of Public Health and Primary Care, University of Cambridge Primary Care Unit, Cambridge, Cambridgeshire, UK.

Background: Anticipatory prescribing (AP) of injectable medications in advance of clinical need is established practice in community end-of-life care. Changes to prescribing guidelines and practice have been reported during the COVID-19 pandemic.

Aims And Objectives: To investigate UK and Ireland clinicians' experiences concerning changes in AP during the COVID-19 pandemic and their recommendations for change. Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335692PMC

COVID-19 presenting as severe, persistent abdominal pain and causing late respiratory compromise in a 33-year-old man.

BMJ Case Rep 2020 Jun 16;13(6). Epub 2020 Jun 16.

Department of Infection & Tropical Medicine, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.

A 33-year-old man presented repeatedly with severe abdominal pain and diarrhoea. Renal colic was suspected, and he was admitted for pain management. Questioning elicited an additional history of sore throat and mild, dry cough. Read More

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http://dx.doi.org/10.1136/bcr-2020-236030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299013PMC

Dexmedetomidine for dyspnoea.

BMJ Support Palliat Care 2020 Jun 11. Epub 2020 Jun 11.

Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.

Dexmedetomidine is a selective α-adrenoreceptor agonist with a broad range of effects, including easily controllable sedation, analgesia and anxiolysis. Because of these favorable features, it has replaced traditional sedatives, such as benzodiazepines, and is becoming the first-line sedative for the patients in intensive care units. Terminally ill patients often need sedatives for symptom management, especially for dyspnoea. Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002334DOI Listing

Outpatient palliative medicine consultations: urgent or routine?

BMJ Support Palliat Care 2020 Jun 11. Epub 2020 Jun 11.

Supportive Care, Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Background: Although outpatient palliative care clinics (OPCCs) provide a venue for early, pre-emptive referral to palliative care on a routine basis, some patients will continue to require urgent referrals. The purpose of this study was to characterise these urgent referrals to determine whether they reflect clinical need or convenience.

Methods: We retrospectively compared new patients in an OPCC who were seen urgently versus those seen at routine appointments. Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002201DOI Listing

Community health workers for pandemic response: a rapid evidence synthesis.

BMJ Glob Health 2020 06;5(6)

The George Institute for Global Health, Vishakhapatnam, India.

Introduction: Coronavirus disease (COVID-19), affects 213 countries or territories globally. We received a request from National Health Systems Resource Centre, a public agency in India, to conduct rapid evidence synthesis (RES) on community health workers (CHWs) for COVID-19 prevention and control in 3 days.

Methods: We searched PubMed, websites of ministries (n=3), public agencies (n=6), multilateral institutions (n=3), COVID-19 resource aggregators (n=5) and preprints (n=1) (without language restrictions) for articles on CHWs in pandemics. Read More

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http://dx.doi.org/10.1136/bmjgh-2020-002769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292038PMC

Provision of palliative care in National Cancer Grid treatment centres in India: a cross-sectional gap analysis survey.

BMJ Support Palliat Care 2020 Jun 9. Epub 2020 Jun 9.

Director (Tata Memorial Hospital), Professor of Thoracic Surgery (Surgical Oncology), Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India.

Objectives: This study aimed to identify gaps in palliative care (PC) provision across the National Cancer Grid (NCG) centres in India.

Methods: We performed a cross-sectional validated web-based survey on 102 NCG cancer centres (Nov '17 to April '18). The survey questionnaire had seven sections collecting data relating to the capacity to provide cancer care and PC, drug availability for pain and symptom control, education, advocacy, and quality assurance activities for PC. Read More

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http://dx.doi.org/10.1136/bmjspcare-2019-002152DOI Listing

Spirituality and religiosity in a palliative medicine population: mixed-methods study.

BMJ Support Palliat Care 2020 Jun 4. Epub 2020 Jun 4.

Palliative and Supportive Care Research Department, Cabrini Health, Melbourne, Victoria, Australia

Background: Spiritual care allows palliative care patients to gain a sense of purpose, meaning and connectedness to the sacred or important while experiencing a serious illness. This study examined how Australian patients conceptualise their spirituality/religiosity, the associations between diagnosis and spiritual/religious activities, and views on the amount of spiritual support received.

Methods: This mixed-methods study used anonymous semistructured questionnaires, which included the Functional Assessment of Chronic Illness Therapy-Spiritual Scale-12 (FACIT-SP-12) and adapted and developed questions examining religion/spirituality's role and support. Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002261DOI Listing

Refractory angina is a growing challenge for palliative medicine: a systematic review of non-invasive interventions.

BMJ Support Palliat Care 2020 Jun 4. Epub 2020 Jun 4.

Palliative Medicine, Trinity Hospice & Palliative Care Services, Blackpool, Lancashire, UK.

Background: Refractory angina can have a significant effect on quality of life. Non-invasive interventions have been suggested but there are few guidelines on management. Our aim was to systematically review all studies that reported non-invasive interventions for refractory angina and report on their effectiveness and safety. Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002202DOI Listing

The KOMPACT-P study: Knee Osteoarthritis Management with Physiotherapy informed by Acceptance and Commitment Therapy-Pilot study protocol.

BMJ Open 2020 Jun 3;10(6):e032675. Epub 2020 Jun 3.

Discipline of Physiotherapy, Sydney School of Health Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.

Introduction: Incidence of total knee arthroplasty (TKA) is projected to rise 276% in 2030, and psychological distress affects up to 42% of people with knee osteoarthritis undergoing TKA, with demonstrated detrimental effects on postoperative outcomes. Few studies have assessed psychological treatment in people awaiting TKA, and these have been psychologist-delivered treatments. No evidence exists regarding psychologically-informed interventions delivered by health professionals currently embedded in TKA clinical pathways. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-032675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279646PMC

Symptom burden and clinical profile of COVID-19 deaths: a rapid systematic review and evidence summary.

BMJ Support Palliat Care 2020 May 28. Epub 2020 May 28.

Marie Curie Palliative Care Research Centre, Cardiff University, Cardiff, UK.

The spread of pandemic COVID-19 has created unprecedented need for information. The pandemic is the cause of significant mortality and with this the need for rapidly disseminated information for palliative care professionals regarding the prevalence of symptoms, their intensity, their resistance or susceptibility to symptom control and the mode of death for patients.

Methods: We undertook a systematic review of published evidence for symptoms in patients with COVID-19 (with a specific emphasis on symptoms at end of life) and on modes of death. Read More

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http://dx.doi.org/10.1136/bmjspcare-2020-002368DOI Listing

Early palliative care: the surprise question and the palliative care screening tool-better together.

BMJ Support Palliat Care 2020 May 25. Epub 2020 May 25.

Institute of Public Health, National Yang-Ming University, Taipei, Taiwan.

Objective: The 'surprise question' (SQ) and the palliative care screening tool (PCST) are the common assessment tools in the early identification of patients requiring palliative care. However, the comparison of their prognostic accuracies has not been extensively studied. This study aimed to compare the prognostic accuracy of SQ and PCST in terms of recognising patients nearing end of life (EOL) and those appropriate for palliative care. Read More

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http://dx.doi.org/10.1136/bmjspcare-2019-002116DOI Listing

Intractable pain and cordotomy.

BMJ Support Palliat Care 2020 May 20. Epub 2020 May 20.

Pain Relief and Supportive Care, Private Hospital La Maddalena, Palermo 90146, Italy

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http://dx.doi.org/10.1136/bmjspcare-2020-002360DOI Listing

Global and regional geographical prevalence of depression in gastric cancer: a systematic review and meta-analysis.

BMJ Support Palliat Care 2020 May 20. Epub 2020 May 20.

Department of Epidemiology, Center for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Sharoud, Iran

Background: Substantial uncertainty exists about the prevalence of depression in patients with gastric cancer. We aimed to summarise the global and regional pooled prevalence of depression among patients with gastric cancer.

Method: Up to February 2020, we searched PubMed/MEDLINE, Embase, Scopus, Web of science (ISI) and PsychINFO to identify published studies on the prevalence of depression among patients with gastric cancer. Read More

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http://dx.doi.org/10.1136/bmjspcare-2019-002050DOI Listing

Evaluating the real-world implementation of the Family Nurse Partnership in England: protocol for a data linkage study.

BMJ Open 2020 May 18;10(5):e038530. Epub 2020 May 18.

Great Ormond Street Institute of Child Health, University College London, London, UK

Introduction: Almost 20 000 babies are born to teenage mothers each year in England, with poorer outcomes for mothers and babies than among older mothers. A nurse home visitation programme in the USA was found to improve a wide range of outcomes for young mothers and their children. However, a randomised controlled trial in England found no effect on short-term primary outcomes, although cognitive development up to age 2 showed improvement. Read More

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http://dx.doi.org/10.1136/bmjopen-2020-038530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239518PMC

Delayed-onset progressive pseudorheumatoid dysplasia with secondary synovial chondromatosis.

BMJ Case Rep 2020 May 18;13(5). Epub 2020 May 18.

Radiology, PGIMER, Chandigarh, India.

A 25-year-old man presented to us with progressive multiple joint pain, enlargement, and restricted movements. X-rays showed platyspondyly, multiple epiphyseal widening, synovial chondromatosis, and decreased bone stock and cortical thickness. Genetic testing showed biallelic pathogenic variants in CCN6 which confirmed the diagnosis of progressive pseudorheumatoid dysplasia. Read More

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http://dx.doi.org/10.1136/bcr-2020-234461DOI Listing

Which men change in intimate partner violence prevention interventions? A trajectory analysis in Rwanda and South Africa.

BMJ Glob Health 2020 May;5(5)

Gender and Health Research Unit, South African Medical Research Council, Pretoria, Gauteng, South Africa.

Introduction: Emerging evidence suggests working with men to prevent intimate partner violence (IPV) perpetration can be effective. However, it is unknown whether all men benefit equally, or whether different groups of men respond differentially to interventions.

Methods: We conducted trajectory modelling using longitudinal data from men enrolled in intervention arms of three IPV trials in South Africa and Rwanda to identify trajectories of IPV perpetration. Read More

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http://dx.doi.org/10.1136/bmjgh-2019-002199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239517PMC

Focus group discussions on low-flow oxygen and bubble CPAP treatments among mothers of young children in Malawi: a CPAP IMPACT substudy.

BMJ Open 2020 May 12;10(5):e034545. Epub 2020 May 12.

Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, United States.

Objective: To determine the acceptability of bubble continuous positive airway pressure (bCPAP) and low-flow oxygen among mothers of children who had received either therapy.

Setting: A district hospital in Salima, Malawi.

Participants: We conducted eight focus group discussions (FGDs) with a total of 54 participants. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-034545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228516PMC
May 2020
2.063 Impact Factor

Learning a new way of living together: a qualitative study exploring the relationship changes and intervention needs of patients with cardiovascular disease and their partners.

BMJ Open 2020 May 6;10(5):e032948. Epub 2020 May 6.

Département de Psychoéducation et de Psychologie, Universite du Quebec en Outaouais, Gatineau, Quebec, Canada.

Objectives: Cardiovascular disease (CVD) not only affects the patient, but has implications for the partner. Emerging evidence suggests that supportive couple relationships enhance CVD outcomes and reduce patient and partner distress. To date, however, little research has been done to address the couple relationship as a potentially important component of cardiac care. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-032948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223018PMC

Cancer immunotherapy and toxic epidermal necrolysis.

BMJ Support Palliat Care 2020 Apr 27. Epub 2020 Apr 27.

The Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of GI Medical Oncology, Peking University School of Oncology, Beijing Cancer Hospital & Institute, Beijing, China.

Objectives: Immunotherapy has come to play an increasingly important role in cancer treatment. Accordingly, immune-related adverse events (irAEs) have drawn considerable attention. In this case, a young female patient developed immune-related toxic epidermal necrolysis (TEN). Read More

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http://dx.doi.org/10.1136/bmjspcare-2019-002135DOI Listing

Human resources and curricula content for early child development implementation: multicountry mixed methods evaluation.

BMJ Open 2020 Apr 26;10(4):e032134. Epub 2020 Apr 26.

Maternal, Adolescent, Reproductive and Child Health Centre, London School of Hygiene and Tropical Medicine, London, UK

Objective: The WHO recommends responsive caregiving and early learning (RCEL) interventions to improve early child development (ECD), and to achieve the Sustainable Development Goals' vision of a world where all children thrive. Implementation of RCEL programmes in low and middle-income countries (LMIC) requires evidence to inform decisions about human resources and curricula content. We aimed to describe human resources and curricula content for implementation of RCEL projects across diverse LMICs, using data from the Grand Challenges Canada Saving Brains ECD portfolio. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-032134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204990PMC
April 2020
2.063 Impact Factor

Rare case of EBV-induced colitis in an immunocompetent individual.

BMJ Open Gastroenterol 2020 25;7(1):e000360. Epub 2020 Mar 25.

Gastroenterology and Hepatology Division, Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA.

Epstein-Barr virus (EBV) is a member of the herpes virus family and affects people worldwide. EBV-infected colitis can occur in patients in immunocompromised states. However, EBV-induced colitis in immunocompetent patients is extremely rare. Read More

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http://dx.doi.org/10.1136/bmjgast-2019-000360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170404PMC

Administration of end-of-life drugs by family caregivers during covid-19 pandemic.

BMJ 2020 Apr 24;369:m1615. Epub 2020 Apr 24.

Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1136/bmj.m1615DOI Listing

Prospective observational study on the pharmacokinetic properties of the Irrua ribavirin regimen used in routine clinical practice in patients with Lassa fever in Nigeria.

BMJ Open 2020 Apr 16;10(4):e036936. Epub 2020 Apr 16.

Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Introduction: Lassa fever (LF) is a severe and often fatal systemic disease in humans and affects a large number of countries in West Africa. Treatment options are limited to supportive care and the broad-spectrum antiviral agent ribavirin. However, evidence for ribavirin efficacy in patients with LF is poor and pharmacokinetic (PK) data are not available. Read More

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http://dx.doi.org/10.1136/bmjopen-2020-036936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200043PMC

Biomarker-guided implementation of the KDIGO guidelines to reduce the occurrence of acute kidney injury in patients after cardiac surgery (PrevAKI-multicentre): protocol for a multicentre, observational study followed by randomised controlled feasibility trial.

BMJ Open 2020 04 6;10(4):e034201. Epub 2020 Apr 6.

Anesthesiology, Intensive Care and Pain Medicine, Universitatsklinikum Munster, Munster, Nordrhein-Westfalen, Germany

Introduction: Acute kidney injury (AKI) is a frequent complication after cardiac surgery with adverse short-term and long-term outcomes. Although prevention of AKI (PrevAKI) is strongly recommended, the optimal strategy is uncertain. The Kidney Disease: Improving Global Outcomes (KDIGO) guideline recommended a bundle of supportive measures in high-risk patients. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-034201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245412PMC
April 2020
2.063 Impact Factor

Young adults with life-limiting or life-threatening conditions: sexuality and relationships support.

BMJ Support Palliat Care 2020 Apr 2. Epub 2020 Apr 2.

Faculty of Wellbeing, Education and Language Studies, The Open University, Milton Keynes, UK.

Objective: The research project addressed the need to support young adults with issues relating to sexuality and relationships though the development of guidance and standards for practice.

Methods: An action research project underpinned by an interpretivist qualitative framework. Participants were recruited to the project via three hospices in the UK. Read More

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http://dx.doi.org/10.1136/bmjspcare-2019-002070DOI Listing

UK palliative medicine trainees and multisource communication skills feedback: an educational tool?

BMJ Support Palliat Care 2020 Mar 31. Epub 2020 Mar 31.

Department of Postgraduate Education, Royal College of Physicians of London, London, London, UK.

Background: Multisource feedback provides ratings of a trainee doctor's performance from a range of assessors and enables 360 degree feedback on communication skills and team working behaviours. It is a tool used throughout palliative medicine training in the UK. There are limited data on the value of multisource feedback from a palliative medicine trainee perspective. Read More

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http://dx.doi.org/10.1136/bmjspcare-2019-002133DOI Listing

Factors impacting on retention, success and equitable participation in clinical academic careers: a scoping review and meta-thematic synthesis.

BMJ Open 2020 Mar 25;10(3):e033480. Epub 2020 Mar 25.

Medical Education Research Unit, Faculty of Medicine, Imperial College London, London, UK

Objectives: To examine and synthesise current evidence on the factors that affect recruitment, retention, participation and progression within the clinical academic pathway, focusing on equitable participation across protected characteristics including gender, ethnicity and sexual orientation.

Design: Scoping review and meta-thematic synthesis.

Data Sources: Web of Science, Google Scholar. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-033480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170560PMC

Preferred place of death in paediatric, teenage and young adult haemato-oncology patients: a retrospective review.

BMJ Support Palliat Care 2020 Mar 24. Epub 2020 Mar 24.

Paediatric Oncology, University College London Hospital, London, UK.

Objectives: Identifying the preferred place of death for children/young people with cancer and determining whether this is achieved is pertinent to inform palliative care service provision. The aims of this retrospective case series review were to determine where children/young people with cancer want to die and whether their preferred place of death was achieved.

Methods: Clinical/demographic details, including preferred and actual places of death, were recorded for 121 patients who died between 2012 and 2016 at a tertiary haematology-oncology centre. Read More

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http://dx.doi.org/10.1136/bmjspcare-2019-002005DOI Listing

Clinical research in cancer palliative care: a metaresearch analysis.

BMJ Support Palliat Care 2020 Jun 24;10(2):249-258. Epub 2020 Mar 24.

Medical Department, EORTC Headquarters, Brussels, Belgium.

Objective: This metaresearch of the clinicaltrials.gov database aims to evaluate how clinical research on palliative care is conducted within the setting of advanced cancer.

Methods: Clinicaltrials. Read More

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http://dx.doi.org/10.1136/bmjspcare-2019-002086DOI Listing

Pain Squad+ smartphone app to support real-time pain treatment for adolescents with cancer: protocol for a randomised controlled trial.

BMJ Open 2020 Mar 16;10(3):e037251. Epub 2020 Mar 16.

Child Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada.

Introduction: Pain negatively affects the health-related quality of life (HRQL) of adolescents with cancer. The Pain Squad+ smartphone-based application (app), has been developed to provide adolescents with real-time pain self-management support. The app uses a validated pain assessment and personalised pain treatment advice with centralised decision support via a registered nurse to enable real-time pain treatment in all settings. Read More

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http://dx.doi.org/10.1136/bmjopen-2020-037251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076249PMC

Psychometric validation of a Patient-Centred Quality of Cancer Care Questionnaire in Mexico.

BMJ Open 2020 Mar 16;10(3):e033114. Epub 2020 Mar 16.

Division of Social Protection and Health, Inter-American Development Bank, Kingston, Jamaica.

Objectives: To develop and validate a Patient-Centred Quality of Cancer Care Questionnaire in Spanish (PCQCCQ-S) appropriate to the Mexican context.

Design: Psychometric validation of a questionnaire.

Setting: Two public oncology hospitals in Mexico City. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-033114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076235PMC

Pediatric Adenotonsillectomy Trial for Snoring (PATS): protocol for a randomised controlled trial to evaluate the effect of adenotonsillectomy in treating mild obstructive sleep-disordered breathing.

BMJ Open 2020 Mar 15;10(3):e033889. Epub 2020 Mar 15.

Division of Sleep Medicine and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Introduction: Mild obstructive sleep-disordered breathing (oSDB), characterised by habitual snoring without frequent apnoeas and hypopnoeas on polysomnography, is prevalent in children and commonly treated with adenotonsillectomy (AT). However, the absence of high-level evidence addressing the role of AT in improving health and behavioural outcomes has contributed to significant geographical variations in care and potential for surgery to be both overused and underused.

Methods And Analysis: The Pediatric Adenotonsillectomy Trial for Snoring (PATS) is a single-blinded, multicentre randomised controlled trial designed to evaluate the effect of AT in treating mild oSDB. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-033889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073822PMC

Prone positioning in a patient with fat embolism syndrome presenting as diffuse alveolar haemorrhage: new perspective.

BMJ Case Rep 2020 Mar 10;13(3). Epub 2020 Mar 10.

Department of Anesthesiology, Critical Care and Pain Medicine, All India Institute of Medical Sciences, New Delhi, India.

Diffuse alveolar haemorrhage (DAH) is a rare complication of fat embolism syndrome leading to severe hypoxaemia due to the effusion of blood into the alveoli from the damaged pulmonary microvasculature. The management is usually supportive with patients being nursed in supine position. The use of prone position ventilation in a DAH has rarely been reported before. Read More

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http://dx.doi.org/10.1136/bcr-2019-233452DOI Listing

Returning to daily life: a qualitative interview study on parents of childhood cancer survivors in Germany.

BMJ Open 2020 Mar 8;10(3):e033730. Epub 2020 Mar 8.

Department of Medical Psychology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Objectives: To investigate experiences of parents of paediatric cancer survivors in cancer-related changes in the parents' daily life (work life, family life, partner relationship and social life) during and after intensive cancer treatment and to examine the reintegration process with its impeding and facilitating factors.

Design: The design of this cross-sectional study involves a qualitative content analysis of semistructured interviews.

Setting: Participants were consecutively recruited in clinical settings throughout Germany. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-033730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064139PMC

'I can do this': a qualitative exploration of acceptability and experiences of a physical activity behaviour change intervention in people with multiple sclerosis in the UK.

BMJ Open 2020 Mar 6;10(3):e029831. Epub 2020 Mar 6.

Ageing Studies Theme, Institute of Environment, Health and Societies, Brunel University London, Uxbridge, UK.

Objectives: The purpose of this study was to explore the experiences of people with multiple sclerosis (MS) who participated in iStep-MS, a feasibility randomised controlled trial of a behaviour change intervention that aimed to increase physical activity and reduce sedentary behaviour.

Design: A qualitative approach was undertaken embedded in the feasibility randomised controlled trial. One-to-one semi-structured interviews were conducted and analysed using Framework analysis. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-029831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064077PMC

A qualitative approach in determining the patient-centered information and supportive care needs of cancer patients in Singapore.

BMJ Open 2020 02 28;10(2):e034178. Epub 2020 Feb 28.

Division of Division of Community Outreach and Philanthropy, National Cancer Centre Singapore, Singapore, Singapore.

Objectives: To qualitatively interpret the information and supportive care needs perceived by cancer patients undergoing treatment in order to get a deeper appreciation of patients' needs and concerns. The intended outcome is to provide baseline knowledge for improving patient-centred strategies to better meet the information and supportive needs of patients.

Design: A qualitative research approach, based on conventional content analysis, was used throughout the research process. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-034178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050354PMC
February 2020

Support from superiors reduces depression in Republic of Korea military officers.

BMJ Mil Health 2020 Feb 27. Epub 2020 Feb 27.

Institute of Health Services Research, Yonsei University, Seodaemun-gu, Seoul, Republic of Korea

Background: The prevalence of depression is relatively high in the Korean military. Social support is a protective factor against depression and is classified into four categories: emotional support-having the sense of feeling loved; instrumental support-receiving material assistance; informational support-receiving advice; appraisal support-feeling valued and respected for one's abilities.

Objective: To investigate the effect of support from one's superior on depression among Republic of Korea (ROK) military officers. Read More

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http://dx.doi.org/10.1136/jramc-2019-001343DOI Listing
February 2020