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    2020 results match your criteria Blood purification[Journal]

    1 OF 41

    Serum Magnesium Abnormality and Influencing Factors of Serum Magnesium Level in Peritoneal Dialysis Patients: A Single-Center Study in Northern China.
    Blood Purif 2017 Dec 14;45(1-3):110-117. Epub 2017 Dec 14.
    Background/aims: Both hypomagnesemia and hypermagnesemia have been associated with cardiovascular diseases, bone diseases, and mortality in dialysis patients. We aimed to investigate the prevalence of and influencing factors for abnormal serum Mg levels in patients on peritoneal dialysis (PD).

    Methods: A cross-sectional study in Peking University People's Hospital recorded the demographic information, clinical characteristics, and laboratory data. Read More

    Nursing Intervention on the Compliance of Hemodialysis Patients with End-Stage Renal Disease: A Meta-Analysis.
    Blood Purif 2017 Dec 12;45(1-3):102-109. Epub 2017 Dec 12.
    Kidney Internal Medicine, Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing, China.
    Background: Dialysis is imperative for patients with end-stage renal disease (ESRD); however, compliance ensures its efficacy. Nursing intervention has been considered to improve compliance. This meta-analysis is aimed at exploring the effects of nursing intervention on dialysis compliance. Read More

    Peritonitis in Children on Chronic Peritoneal Dialysis: The Experience of a Large National Pediatric Cohort.
    Blood Purif 2017 Dec 14;45(1-3):118-125. Epub 2017 Dec 14.
    Department of Medicine, São Paulo State University (UNESP), Botucatu, Brazil.
    Background: We performed this study to evaluate the incidence, risk factors, microbiology, treatment, and outcome of peritonitis in pediatric Peritoneal dialysis (PD) patients at a nationwide prospective study.

    Methodology: Patients younger than 18 years recruited in the BRAZPD II study from 2004 to 2011, who presented their first peritonitis episode, were included in the study.

    Results: We found 125 first episodes of peritonitis in 491 children PD patients (0. Read More

    Implication of Haemodiafiltration Flow Rate on Amikacin Pharmacokinetic Parameters in Critically Ill Patients.
    Blood Purif 2017 Dec 12;45(1-3):88-94. Epub 2017 Dec 12.
    Intensive Care Unit, Hospital Universitario y Politécnico La Fe, Avenida Fernando Abríl Martorell, Valencia, Spain.
    Background: To analyse the effect of haemodiafiltration (CVVHDF) flow rate on amikacin pharmacokinetics and blood concentrations.

    Methods: Prospective observational study. Patients receiving CVVHDF and amikacin treatment were included. Read More

    Prognostic Factors and Efficacy for Continuous Renal Replacement Therapy in Critically Ill Patients: A Chinese Single-Center Retrospective Study.
    Blood Purif 2017 Dec 7;45(1-3):53-60. Epub 2017 Dec 7.
    Background: There is controversy about the efficacy and prognostic factors for continuous renal replacement therapy (CRRT) in China due to practice variation. Our aim is to investigate these questions.

    Method: A total of 613 adult patients receiving CRRT in last 3 years from one Chinese ICU were enrolled. Read More

    Effect of Cinacalcet Combined with Calcitriol on the Clinical Outcome and Bone Metabolism in Patients on Hemodialysis with Severe Secondary Hyperparathyroidism.
    Blood Purif 2017 Dec 7;45(1-3):73-78. Epub 2017 Dec 7.
    Objective: To observe the clinical outcome and the effect of bone metabolism of cinacalcet combined with calcitriol in maintenance hemodialysis (MHD) patients with severe secondary hyperparathyroidism (SHPT).

    Methods: Thirty MHD patients with SHPT were enrolled into the study. All patients were given cinacalcet 25-75 mg and 0. Read More

    A Simplified Approach to Extravascular Lung Water Assessment Using Point-of-Care Ultrasound in Patients with End-Stage Chronic Renal Failure Undergoing Hemodialysis.
    Blood Purif 2017 Dec 7;45(1-3):79-87. Epub 2017 Dec 7.
    Department of Anesthesia, Montreal Heart Institute and Université de Montréal, Montreal, Québec, Canada.
    Background: Fluid overload leading to pulmonary congestion is an important issue in patients undergoing hemodialysis. This study aimed to determine if a simplified method of extravascular lung water assessment using ultrasound provided clinically relevant information.

    Methods: This prospective study recruited 47 patients from a single hemodialysis center. Read More

    Sodium Prescription in the Prevention of Intradialytic Hypotension: New Insights into an Old Concept?
    Blood Purif 2017 Nov 23;45(1-3):61-70. Epub 2017 Nov 23.
    Nephrology, Dialysis and Renal Transplantation Unit, S. Orsola University Hospital, Bologna, Italy.
    Background: Sodium prescription in patients with intradialytic hypotension remains a challenge for the attending nephrologist, as it increases dialysate conductivity in hypotension-prone patients, thereby adding to dietary sodium levels.

    Methods: New sodium prescription strategies are now available, including the use of a mathematical model to compute the sodium mass to be removed during dialysis as a physiological controller.

    Results: This review describes the sodium load of patients with end-stage renal disease on chronic hemodialysis (HD) and discusses 2 strategies to remove excess sodium in patients prone to intradialytic hypotension, namely, Profiled HD and the hemodiafiltration Aequilibrium System. Read More

    Transport Characteristics of Asymmetric Cellulose Triacetate Hemodialysis Membranes.
    Blood Purif 2017 Nov 22;45(1-3):46-52. Epub 2017 Nov 22.
    Department of Chemical Engineering, The Pennsylvania State University, University Park, PA, USA.
    Aims: The objective of this study was to compare the transport characteristics of highly asymmetric cellulose triacetate (ATA™) membranes with that of both symmetric cellulose triacetate and asymmetric polysulfone membranes.

    Methods: Data were obtained for solute clearance and sieving coefficients of vitamin B12 and a range of polydisperse dextrans using ATA™ SOLACEA-25H and Optiflux F250NR polysulfone dialyzers. Results for these, and the CT190 symmetric cellulose triacetate dialyzer, were analyzed using available membrane transport models. Read More

    Clinical Benefits of High-Volume Hemofiltration in Critically Ill Pediatric Patients with Severe Sepsis: A Retrospective Cohort Study.
    Blood Purif 2017 Nov 22;45(1-3):18-27. Epub 2017 Nov 22.
    Department of Critical Care Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Putuo District, Shanghai, China.
    Aims: The study aimed to assess the clinical benefits of high-volume hemofiltration (HVHF) in pediatric patients with severe sepsis compared with standard-volume continuous veno-venous hemofiltration (CVVH).

    Methods: We retrospectively analyzed the medical records of 155 pediatric patients with severe sepsis admitted to the pediatric intensive care unit of Shanghai Children's Hospital from January 2010 to June 2016. A total of 93 patients were treated with HVHF and 62 patients were treated with CVVH. Read More

    Endotoxin Effects on Cardiac and Renal Functions and Cardiorenal Syndromes.
    Blood Purif 2017 Nov 22;44(4):314-326. Epub 2017 Nov 22.
    Department of Nephrology, Dialysis and Transplant, San Bortolo Hospital, Agrigento, Italy.
    Gram-negative sepsis is a major cause of morbidity and mortality in critical ill patients. Recent findings in molecular biology and in signaling pathways have enhanced our understanding of its pathogenesis and opened up opportunities of innovative therapeutic approaches. Endotoxin plays a pivotal role in the pathogenesis of multi-organ dysfunction in the setting of gram-negative sepsis. Read More

    Maintained Folic Acid Supplementation Reduces the Risk of Mortality in Continuous Ambulatory Peritoneal Dialysis Patients.
    Blood Purif 2017 Nov 22;45(1-3):28-35. Epub 2017 Nov 22.
    Department of Nephrology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
    Background: The association between folic acid (FA) supplementation and mortality in continuous ambulatory peritoneal dialysis (CAPD) patients is unclear.

    Methods: FA exposure was calculated as a percentage of cumulative duration of drug usage to total follow-up duration (FA%). A total of 1,358 patients were classified by a cutoff value of FA%. Read More

    A Randomized Controlled Trial of Comparing Ultrasound-Guided Transversus Abdominis Plane Block with Local Anesthetic Infiltration in Peritoneal Dialysis Catheter Implantation.
    Blood Purif 2017 Nov 22;45(1-3):8-14. Epub 2017 Nov 22.
    Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, PR China.
    Background: The ultrasound-guided transversus abdominis plane (TAP) block has been demonstrated as a useful analgesia technique in lower-abdomen surgeries. We hypothesized that it could be the principal anesthesia technique for end-stage renal disease (ESRD) patients undergoing peritoneal dialysis (PD) catheter (PDC) implantation using the open dissection method.

    Methods: This was a single-center, prospective, randomized, and double-blinded study. Read More

    Association between Extreme Values of Markers of Chronic Kidney Disease: Mineral and Bone Disorder and 5-Year Mortality among Prevalent Hemodialysis Patients.
    Blood Purif 2017 Nov 22;45(1-3):1-7. Epub 2017 Nov 22.
    Department of Nephrology, Tianjin Union Medicine Center, Tianjin, PR China.
    Background/aims: We examined the association between markers of chronic kidney disease - mineral and bone disorder (CKD-MBD) and mortality in hemodialysis (HD) patients.

    Methods: We retrospectively reviewed the association between markers of CKD-MBD and mortality in 1,126 HD patients from 2009 to 2013 with baseline (B), time-average (TA), and time-dependent (TD) Cox regression models.

    Results: Hypercalcemia (10. Read More

    Higher versus Lower Continuous Renal Replacement Therapy Intensity in Critically ill Patients with Liver Dysfunction.
    Blood Purif 2017 Nov 22;45(1-3):36-43. Epub 2017 Nov 22.
    Department of Intensive Care, Austin Hospital, Heidelberg, VIC, Australia.
    Aims: To study the association between higher versus lower continuous renal replacement therapy (CRRT) intensity and mortality in critically ill patients with combined acute kidney injury and liver dysfunction.

    Methods: Post-hoc analysis of patients with liver dysfunction (Sequential Organ Failure Assessment liver score ≥2 or diagnosis of liver failure/transplant) included in the Randomized Evaluation of Normal versus Augmented Level renal replacement therapy (RENAL) trial.

    Results: Of 444 patients, 210 (47. Read More

    Cardiac Remodelling in Patients Undergoing in-Centre Nocturnal Haemodialysis: Results from the MIDNIGHT Study, a Non-Randomized Controlled Trial.
    Blood Purif 2017 Oct 31;44(4):301-310. Epub 2017 Oct 31.
    National Centre for Sport and Exercise Medicine, Loughborough, UK.
    Evidence suggests extended-hours haemodialysis (HD) may improve cardiovascular, medical and quality-of-life outcomes. In-centre nocturnal haemodialysis (INHD) is an established but underutilized method of providing extended-hours treatment. This 6-month, non-randomized controlled trial (ISRCTN16672784) recruited 13 INHD patients and 12 control patients on conventional HD. Read More

    Thiamine Diphosphate Status and Dialysis-Related Losses in End-Stage Kidney Disease Patients Treated with Hemodialysis.
    Blood Purif 2017 Oct 28;44(4):294-300. Epub 2017 Oct 28.
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdańsk, Gdańsk, Poland.
    Aim: (1) To describe the whole blood content of thiamine diphosphate (TDP), a biologically active form of vitamin B1 in end-stage kidney disease patients treated with hemodialysis (HD); (2) to establish the impact of a single HD procedure on TDP blood concentrations; and (3) to describe potential explanatory variables influencing TDP dialysis related losses, including dialysis prescription, vitamin B1 dietary intake and supplementation.

    Methods: Single-center, cross-sectional study in 50 clinically stable maintenance HD patients. The assessment of whole blood TDP with the High Performance Liquid Chromatography method, before and after a single, middle-week dialysis session and analysis of clinical and laboratory parameters potentially influencing TDP status Results: We report a significant difference in TDP levels before and after HD sessions - 42. Read More

    Early Continuous Veno-Venous Hemofiltration Is Effective in Decreasing Intra-Abdominal Pressure and Serum Interleukin-8 Level in Severe Acute Pancreatitis Patients with Abdominal Compartment Syndrome.
    Blood Purif 2017 Oct 25;44(4):276-282. Epub 2017 Oct 25.
    Digestive Department, Affiliated Yidu Central Hospital of Weifang Medical College, Qingzhou, China.
    Objective: The aim of this study was to evaluate the efficacy of early continuous veno-venous hemofiltration (CVVH) in decreasing the intra-abdominal pressure (IAP) and serum interleukin-8 (IL-8) level in severe acute pancreatitis (SAP) patients with abdominal compartment syndrome (ACS).

    Methods: Twenty-five ACS patients of SAP were enrolled in a prospective study conducted according to the standard management protocol. They were treated in the intensive care unit (ICU) of Affiliated Yidu Central Hospital of Weifang Medical College and underwent CVVH. Read More

    Urgent-Start Peritoneal Dialysis: The First Year of Brazilian Experience.
    Blood Purif 2017 Oct 25;44(4):283-287. Epub 2017 Oct 25.
    São Paulo State University - UNESP, Alameda dasHortencias, Botucatu, Brazil.
    Background: This study aimed to evaluate mechanical and infectious complications associated with urgent-start peritoneal dialysis (PD) and patients and technique survival in the first 180 days.

    Methods: It was a prospective study that evaluated chronic patients who started unplanned PD using high-volume PD (HVPD) right after (<72 h) PD catheter placement. After hospital discharge, patients were treated with intermittent PD on alternate days in a dialysis unit until family training was provided. Read More

    Vitamin E-Coated Dialyzer Inhibits Oxidative Stress.
    Blood Purif 2017 Oct 25;44(4):288-293. Epub 2017 Oct 25.
    Department of Healthcare and Regulatory Sciences, School of Pharmaceuticy, Showa University, Shinagawa-ku, Japan.
    Aim: To examine the effects of vitamin E-coated dialyzer on oxidative stress in vitro.

    Methods: A dialyzer with a synthetic polymer membrane (APS-11SA) and vitamin E-coated dialyzer (VPS-11SA) were connected to a blood tubing line, and U937 cells were circulated in the device. The circulating fluid was collected at 1, 2, 5, 10, 25, and 50 cycles, which are estimated numbers of passes through the dialyzer. Read More

    A Call to Action to Develop Integrated Curricula in Cardiorenal Medicine.
    Blood Purif 2017 Oct 25;44(4):251-259. Epub 2017 Oct 25.
    Department of Nephrology, San Bortolo Hospital, Vicenza, Italy.
    With the adoption of the new definition and classification of cardiorenal syndrome (CRS) and its relevant subtypes, much attention has been placed on elucidating the mechanisms of heart and kidney interactions. Of great interest are the pathophysiological pathways by which acute heart failure may result in acute kidney injury (AKI; type 1), chronic heart failure accelerating the progression of chronic kidney disease (CKD; type 2), AKI provoking cardiac events (type 3), and CKD increasing the risk and severity of cardiovascular disease (type 4). A remarkable interest has also been placed on the acute and chronic systemic conditions, such as sepsis and diabetes, which simultaneously affect heart and kidney function (type 5). Read More

    Clearance of Selected Plasma Cytokines with Continuous Veno-Venous Hemodialysis Using Ultraflux EMiC2 versus Ultraflux AV1000S.
    Blood Purif 2017 Oct 7;44(4):260-266. Epub 2017 Oct 7.
    Christian Doppler Laboratory for Innovative Therapy Approaches in Sepsis, Donau University Krems, Krems an der Donau, Austria.
    Background: High cutoff hemofilters might support the restoration of immune homeostasis in systemic inflammation by depleting inflammatory mediators from the circulation.

    Methods: Interleukin (IL)-6, IL-8, IL-10, and tumor necrosis factor-alpha depletion was assessed in 30 sepsis patients with acute renal failure using continuous veno-venous hemodialysis with high cutoff versus standard filters (CVVHD-HCO vs. CVVHD-STD) over 48 h. Read More

    Prognostic Factors of Human Immunodeficiency Virus-Infected Patients on Chronic Hemodialysis.
    Blood Purif 2017 3;44(3):244-250. Epub 2017 Oct 3.
    Department of Nephrology, Hospital de Santa Cruz, Lisbon, Portugal.
    Background/aims: The number of human immunodeficiency virus (HIV)-infected patients on hemodialysis (HD) have increased, and their prognostic factors are still poorly clarified. The study aimed to identify factors that can influence the survival of HIV-infected patients on HD.

    Methods: We performed a retrospective cohort study of 44 HIV-infected patients on HD. Read More

    Troponin I Levels in Asymptomatic Hemodialysis Patients.
    Blood Purif 2017 29;44(3):236-243. Epub 2017 Sep 29.
    Division of Cardiology, San Paolo Hospital, University of Milan, Italy.
    Background: End-stage renal disease (ESRD) represents a situation in which persistently elevated levels of cardiac troponins I (cTnI) are frequently found in the absence of clinically evident cardiac disease. Moreover, the effect of hemodialysis (HD) on cTnI levels is not definitively elucidated. The aim of this study was to investigate the effects of HD on cTnI levels in ESRD patients. Read More

    Effect of Cardiac Surgery-Associated Acute Kidney Injury on Long-Term Outcomes of Chinese Patients: A Historical Cohort Study.
    Blood Purif 2017 6;44(3):227-233. Epub 2017 Sep 6.
    Department of Nephrology, The First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), Nanjing, China.
    Background/aims: To evaluate the long-term outcomes of Chinese patients with cardiac surgery-associated acute kidney injury (CSA-AKI).

    Methods: Patients who underwent cardiac surgery with a median 3-year follow-up were enrolled. The long-term survival rate and the incidence of chronic kidney disease (CKD) were recorded, and related risk factors were analyzed. Read More

    Management of Nephrotic Syndrome: A Case Report from Lao PDR.
    Blood Purif 2017 5;44 Suppl 1:31-34. Epub 2017 Sep 5.
    Hemodialysis Center and Division of Nephrology, Mittaphab Hospital, Vientiane, Lao PDR.
    We report the case of a 23-year-old woman with a 2-week history of swelling around the eyes and both legs, and generalized body swelling. She had a history of chronic constipation and poor diet but no fever, recent illnesses, or hematuria. Examination revealed bilateral pedal edema and mild ascites. Read More

    Acute Kidney Injury due to Fish Gallbladder Ingestion: A Case Report from Cambodia.
    Blood Purif 2017 5;44 Suppl 1:22-25. Epub 2017 Sep 5.
    Chea Sim Hemodialysis Center, Calmette Hospital, Phnom Penh, Cambodia.
    We report the case of a 22-year-old woman with a 3-day history of watery stool, generalized abdominal pain, repeated vomiting, and decreased urine output following the consumption of fish gallbladder for self-treatment of acne. She was admitted and received empirical antiemetic, proton pump inhibitor, and intravenous saline treatment. Urine output reduced drastically with markedly elevated urea and creatinine, and she underwent urgent hemodialysis (HD). Read More

    Acute Kidney Injury following Ingestion of Henna Leaf Extract: A Case Report from Myanmar.
    Blood Purif 2017 5;44 Suppl 1:41-45. Epub 2017 Sep 5.
    Nephrology Department, Thingangyun Sanpya General Hospital (TSGH), Yangon, Myanmar.
    Alternative medicine is gaining popularity worldwide. In Asia, particularly Southeast Asia, herbal medicine plays an important role in healthcare. A 34-year-old man from Yangon, Myanmar, was admitted to the medical ward of our hospital after ingesting a herbal remedy of boiled henna leaves (Dan Ywet in Burmese). Read More

    Support for Dialysis Therapy in Vietnam, Cambodia, and Myanmar by Japanese Societies in the Field of Blood Purification.
    Blood Purif 2017 5;44 Suppl 1:55-61. Epub 2017 Sep 5.
    Kitasato University School of Allied Health Sciences, Kanagawa, Japan.
    With recent economic development in Southeast Asia, there have been improvements in medical services and healthcare provision. This has led to increased numbers of dialysis patients and increased numbers of dialysis facilities in the region. To assist economically developing countries in managing this change, support projects from Japan have been conducted in the region since around 2007. Read More

    Severe Secondary Hyperparathyroidism in a Hemodialysis Patient: A Case Report from Mongolia.
    Blood Purif 2017 5;44 Suppl 1:35-40. Epub 2017 Sep 5.
    Nephrology Center, First Central Hospital of Mongolia, Ulaanbaatar, Mongolia.
    Secondary hyperparathyroidism (SHPT) occurs in patients with chronic renal failure complicated with renal bone disease and soft tissue/vascular calcification. In dialysis patients with severe SHPT, medical treatment may fail and parathyroidectomy (PTX) is indicated for definitive treatment. Severe hypocalcemia from hungry bone disease or postoperative hypoparathyroidism may occur during the postoperative period. Read More

    Mineral and Bone Disorder in Chronic Kidney Disease: A Case Report from Vietnam.
    Blood Purif 2017 5;44 Suppl 1:46-51. Epub 2017 Sep 5.
    Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.
    We report a case of calcium pyrophosphate dihydrate deposition disease (CPDD) involving a patient on maintenance hemodialysis (MHD). The 32-year-old man presented in August 2016 with a complaint of left shoulder swelling of 8 months' duration with no trauma or fever. He was diagnosed with nephrotic syndrome in 1998, which progressed to ESRD. Read More

    Prospects for Vascular Access Education in Developing Countries: Current Situation in Cambodia.
    Blood Purif 2017 5;44 Suppl 1:52-54. Epub 2017 Sep 5.
    Department of Urology, Osaka City University Graduate School of Medicine, Osaka, and Ubiquitous Blood Purification International, Yokohama, Japan.
    We report our activities training doctors on vascular access procedures at International University (IU) Hospital in Cambodia through a program facilitated by Ubiquitous Blood Purification International, a nonprofit organization that provides medical support to developing countries in the field of dialysis medicine. Six doctors from Japan have been involved in the education of medical personnel at IU, and we have collectively visited Cambodia about 15 times from 2010 to 2016. In these visits, we have performed many operations, including 42 for arteriovenous fistula, 1 arteriovenous graft, and 1 percutaneous transluminal angioplasty. Read More

    Typical Hemodialysis in India: A Case Report.
    Blood Purif 2017 5;44 Suppl 1:26-30. Epub 2017 Sep 5.
    Madras Medical Mission, Chennai, India.
    We report here a typical case of a patient on hemodialysis (HD) for end-stage renal disease (ESRD) in India that highlights some of the management issues encountered in a country with an enormous burden of ESRD and major challenges of underdialysis and management of comorbidities. The patient, a 42-year-old multiparous woman with chronic kidney disease (CKD) stage V, type 2 diabetes mellitus, and hypertension is a homemaker from a middle-class family, living in a large city, with no family history of CKD. From May 2013 to December 2016, she has been receiving twice-weekly maintenance HD for 4 h (intermittent HD); access was via an internal jugular line initially and then via a left brachiocephalic arteriovenous fistula (AVF) from late June 2013. Read More

    Increasing Haemodialytic Clearances as Residual Renal Function Declines: An Incremental Approach.
    Blood Purif 2017 16;44(3):217-226. Epub 2017 Aug 16.
    Faculty of Medicine, Mahasarakham University, Mahasarakham, Thailand.
    Many patients with chronic kidney disease start undergoing thrice-weekly haemodialysis (HD), aiming for an HD sessional dialyzer urea clearance target, irrespective of whether they have residual renal function (RRF). While increasing sessional dialyzer urea clearance above a target of 1.2 has not been shown to improve patient survival, it has been shown that the preservation of RRF improves patient self-reported outcomes and survival. Read More

    Elimination Rates of Electrolytes, Vitamins, and Trace Elements during Continuous Renal Replacement Therapy with Citrate Continuous Veno-Venous Hemodialysis: Influence of Filter Lifetime.
    Blood Purif 2017 9;44(3):210-216. Epub 2017 Aug 9.
    Department of Cardiac Anesthesiology, University Hospital Ulm, Ulm, Germany.
    Background/aims: During continuous renal replacement therapy, relevant losses of nutritional substrates, vitamins, and trace elements via the filter may occur. We investigated filter lifetime efficiency during a 72-h treatment period.

    Methods: This prospective study included 40 patients undergoing citrate continuous veno-venous hemodialysis (CVVHD). Read More

    Therapeutic Plasma Exchange in Neonates and Infants: Successful Use of a Miniaturized Machine.
    Blood Purif 2017 31;44(2):100-105. Epub 2017 Mar 31.
    Nephrology, Dialysis and Transplant Unit, Department of Woman's and Child's Health, University-Hospital of Padova, Padova, Italy.
    Therapeutic plasma exchange (TPE) in neonates and small infants is a treatment method at the forefront that may become a potentially life-saving procedure in a wide array of severe conditions. Indications for TPE in the pediatric population have been mainly derived from adult literature, with neonatal hyperbilirubinemia being the most notable exception. The only alternative to TPE in small pediatric patients is manual blood exchange transfusion, which, however, bears an unacceptably high risk of severe complications. Read More

    Anatomy Revisited: Hemodialysis Catheter Malposition in the Left Ascending Lumbar Vein.
    Blood Purif 2017 1;44(3):206-209. Epub 2017 Jul 1.
    Medical Clinic III, Department of Nephrology, University Hospital Frankfurt, Frankfurt, Germany.
    In selected cases, cuffed tunneled catheters via the iliac vein are implanted as a last resort access for hemodialysis. To monitor the correct position, sonography of the inferior vena cava (IVC) is sufficient in most cases. Position control using an X-ray of the abdomen is not routinely recommended when femoral catheters are implanted. Read More

    Metformin-Associated Lactic Acidosis Undergoing Renal Replacement Therapy in Intensive Care Units: A Five-Million Population-Based Study in the North-West of Italy.
    Blood Purif 2017 1;44(3):198-205. Epub 2017 Jul 1.
    Department of General and Specialist Medicine, Nephrology, Dialysis and Transplantation U, CTO Hospital, Torino, Italy.
    Background: Metformin-associated lactic acidosis (MALA) is a severe complication of drug administration with significant morbidity and mortality. So far no study in large population areas have examined the incidence, clinical profile and outcome of acute kidney injury (AKI)-MALA patients admitted in intensive care units (ICUs) and treated by renal replacement therapy (MALA-RRT).

    Methods: Retrospective analysis over a 6-year period (2010-2015) in Piedmont and Aosta Valley regions (5,305,940 inhabitants, 141,174 diabetics treated with metformin) of all MALA-RRT cases. Read More

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