2,168 results match your criteria Blood purification[Journal]


Misplacement of Tunneled Hemodialysis Catheter into Azygos Vein: Left or Right Jugular Insertion Has Similar Susceptibility.

Blood Purif 2019 Feb 14:1-9. Epub 2019 Feb 14.

Department of Nephrology, University of Hong Kong-Shenzhen Hospital, Shenzhen,

Background: Central venous catheter (CVC) is commonly used to provide access for hemodialysis (HD) when arteriovenous access is not available. The misplacement of CVC into azygos vein (AV) is a rare but a potential serious complication. Previous reports communicated the opinion that left-sided catheterization predisposed to AV misplacement, but these reports concentrated on peripherally inserted CVCs, placed for indications rather than HD. Read More

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http://dx.doi.org/10.1159/000497231DOI Listing
February 2019

Uremic Patients with Increased Vascular Calcification Score Have Serum with High Calcific Potential: Role of Vascular Smooth Muscle Cell Osteoblastic Differentiation and Apoptosis.

Blood Purif 2019 Feb 6:1-8. Epub 2019 Feb 6.

Renal Division, ASST Santi Paolo e Carlo, Department of Health Sciences, University of Milan, Milan,

Background/aims: Uremic patients experience premature vascular ageing that causes cardiovascular morbidity. In this study, we investigated the relationship between uremic serum calcific potential induced by high phosphate (Pi) and vascular calcification score (VCS).

Methods: Vascular smooth muscle cells (VSMCs) were cultured with 3. Read More

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http://dx.doi.org/10.1159/000497229DOI Listing
February 2019
3 Reads

Multi-Biomarkers Panel in Cardiac Surgery Patients.

Blood Purif 2019 Feb 6. Epub 2019 Feb 6.

IRRIV-International Renal Research Institute Vicenza, Vicenza, Italy.

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http://dx.doi.org/10.1159/000497230DOI Listing
February 2019

Chronic Kidney Disease: Exploring Value-Based Healthcare as a Potential Viable Solution.

Blood Purif 2019 Feb 1;47(1-3):156-165. Epub 2019 Feb 1.

Care Value Management EMEA, Fresenius Medical Care, Bad Homburg, Germany.

Background: Increasing healthcare expenditures have triggered a trend from volume to value by linking patient outcome to costs. This concept first described as value-based healthcare (VBHC) by Michael Porter is especially applicable for chronic conditions. This article aims to explore the applicability of the VBHC framework to the chronic kidney disease (CKD) care area. Read More

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http://dx.doi.org/10.1159/000496681DOI Listing
February 2019

Maximum Glomerular Filtration Decline Rate is Associated with Mortality and Poor Renal Outcome in Chronic Kidney Disease Patients.

Blood Purif 2019 Feb 1:1-7. Epub 2019 Feb 1.

Division of Nephrology, Asia University Hospital, Taichung,

Background: Glomerular filtrate rate (GFR) decline is associated with increased risk of dialysis in patients with chronic kidney disease (CKD). It is unclear whether the maximum, the minimum, or the average of GFR decline rate is associated with the risk of mortality and the initiation of renal replacement therapy (RRT). We investigated prognostic role of the maximum, the minimum, and the average of GFR decline rate in patients with CKD not yet on dialysis. Read More

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http://dx.doi.org/10.1159/000496082DOI Listing
February 2019

ACUsmart Continuous Renal Replacement Therapy Platform: Multicenter Pilot Study for Technical and Clinical Assessment (A.M.P. Study).

Blood Purif 2019 Feb 1:1-7. Epub 2019 Feb 1.

Department of Nephrology, Dialysis and Transplantation and International Renal Research Institute of Vicenza, San Bortolo Hospital, Vicenza, Italy.

Background: ACUsmart (Medica S.P.A. Read More

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http://dx.doi.org/10.1159/000496090DOI Listing
February 2019
2 Reads

Sclerostin/Receptor Related Protein 4 and Ginkgo Biloba Extract Alleviates β-Glycerophosphate-Induced Vascular Smooth Muscle Cell Calcification By Inhibiting Wnt/β-Catenin Pathway.

Blood Purif 2019 Jan 30:1-7. Epub 2019 Jan 30.

Department of Nephrology, The First Hospital of China Medical University, Shenyang,

Background: Abnormal mineral metabolism in patients with chronic kidney disease (CKD) may lead to vascular calcification, which is markedly associated with adverse events, including ischemic cardiac diseases and all-cause cardiovascular mortality. Thus, preventing and treating vascular calcification play an important role in improving the prognosis of CKD patients.

Objectives: To investigate the potential functions of sclerostin and low-density lipoprotein receptor-related protein 4 (Lrp4) in alleviating the β-glycerophosphate (β-GP)-induced vascular smooth muscle cell (VSMC) calcification, and the protective effect of Ginkgo biloba extract (GBE). Read More

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http://dx.doi.org/10.1159/000496219DOI Listing
January 2019
1 Read

Study on the Prevalence of Vascular Calcification in Different Types of Arteries and Influencing Factors in Maintenance Peritoneal Dialysis Patients.

Blood Purif 2019 Jan 30:1-9. Epub 2019 Jan 30.

Department of Nephrology, Peking University People's Hospital, Beijing, China.

Objective: To investigate the occurrence of vascular calcification (VC) in different types of arteries in patients with maintenance peritoneal dialysis (PD) patients and its influencing factors.

Methods: This study enrolled PD patients with stable status who has received PD treatment for more than 6 months in Peking University People's Hospital. We used plain X-ray films of abdomen, pelvis, and hands to quantitatively evaluate VC of large artery (abdominal aorta, iliac artery), medium artery (femoral artery, radial artery), and small artery (finger arteries). Read More

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http://dx.doi.org/10.1159/000496218DOI Listing
January 2019
1 Read

Improved Control of Secondary Hyperparathyroidism in Hemodialysis Patients Switching from Oral Cinacalcet to Intravenous Etelcalcetide, Especially in Nonadherent Patients.

Blood Purif 2019 Jan 30:1-9. Epub 2019 Jan 30.

Department of Nephrology and Renal Transplantation, Hospital Clínic de Barcelona, Barcelona,

Background: Etelcalcetide is a novel second-generation calcimimetic that, because of its intravenous administration, could improve treatment adherence in secondary hyperparathyroidism (SHPT). The aim of this study was to evaluate the effectiveness of etelcalcetide compared with that of cinacalcet in controlling SHPT in patients under hemodialysis.

Methods: A prospective observational study was performed in 29 patients with SHPT under hemodialysis who switched from cinacalcet to etelcalcetide with a follow-up of 6 months. Read More

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http://dx.doi.org/10.1159/000496562DOI Listing
January 2019
1 Read

Effects of Multidisciplinary Team Care Based on 5E's Renal Rehabilitation for Peritoneal Dialysis Patients in Guangxi Zhuang Autonomous Region of China: A Randomized Controlled Trial.

Blood Purif 2019 Jan 30:1-9. Epub 2019 Jan 30.

Department of Nutritional, First Affiliated Hospital of Guangxi Medical University, Nanning, China.

Background: The number of patients with peritoneal dialysis (PD) in China has been increasing year after year, but there are still some challenge in the management of PD patients, and the efficient and effective method has yet to be developed. Multidisciplinary team (MDT) is to create a standardized, individualized, and continuous integrated treatment program for the patients, to ensure the best efficacy and improve patient outcomes. 5E's renal rehabilitation was originally developed by the Life Options Rehabilitation Advisory Council in 1997 to achieve better management of PD patients. Read More

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http://dx.doi.org/10.1159/000496823DOI Listing
January 2019

Meta-Analysis of the Association between Fibroblast Growth Factor 23 and Mortality and Cardiovascular Events in Hemodialysis Patients.

Blood Purif 2019 Jan 30:1-7. Epub 2019 Jan 30.

Departments of Nephrology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.

Introduction: This study was conducted to ensure the correlation between fibroblast growth factor 23 (FGF23) and death and cardiovascular events in hemodialysis patients.

Methods: We conducted a literature search of PubMed database to April 2018 for relevant articles that reported the association between FGF23 and risk of all-cause mortality and cardiovascular disease (CVD) events. The meta-analysis was performed using the Revman 5. Read More

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http://dx.doi.org/10.1159/000496220DOI Listing
January 2019

Clearance of Magnesium in Peritoneal Dialysis Patients: A Single-Center Study.

Blood Purif 2019 Jan 30:1-7. Epub 2019 Jan 30.

Department of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Objective: This retrospective study aimed to investigate the clearance of magnesium (Mg) in peritoneal dialysis (PD) patients and its influencing factors.

Methods: The demographic information, clinical characteristics and laboratory data of the patients were collected. According to the corrected serum Mg (cS-Mg) concentration, patients were divided into 3 groups including hypomagnesemia (Mg2+ < 0. Read More

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http://dx.doi.org/10.1159/000496217DOI Listing
January 2019
1 Read

Ectopic Calcification of Fibrin Sheath on the Catheter.

Blood Purif 2019 Jan 30:1-3. Epub 2019 Jan 30.

Department of Kidney Disease and Blood Purification, Institute of Urology and Key Laboratory of Tianjin, The Second Hospital of Tianjin Medical University, Tianjin,

We describe a case of hemodialysis catheter that appeared to be encased in a sleeve-shaped fibrous sheath with calcification. Ectopic calcification is a serious complication in hemodialysis patients with calcium-phosphorus metabolism disorder. Clinical awareness and understanding of this condition is imperative to the prevention and management of ectopic calcification. Read More

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https://www.karger.com/Article/FullText/496231
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http://dx.doi.org/10.1159/000496231DOI Listing
January 2019
3 Reads

Differential Molecular Modeling Predictions of Mid and Conventional Dialysate Flows.

Blood Purif 2019 Jan 30:1-8. Epub 2019 Jan 30.

Palo Alto Medical Foundation, Palo Alto, California,

Background: High dialysate flow rates (QD) of 500-800 mL/min are used to maximize urea removal during conventional hemodialysis. There are few data describing hemodialysis with use of mid-rate QD (300 mL/min).

Methods: We constructed uremic solute (urea, beta2-microglobulin and phosphate) kinetic models at varying volumes of distribution and blood flow rates to predict solute clearances at QD of 300 and 500 mL/min. Read More

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http://dx.doi.org/10.1159/000495022DOI Listing
January 2019

Effects of Peritoneal Dialysis on Clinical Factors and Functional Performance.

Blood Purif 2019 Jan 30:1-7. Epub 2019 Jan 30.

Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung,

Background: We investigated the longitudinal trend of functional performance in peritoneal dialysis (PD) patients over 1 year after PD commencement and its related clinical parameters.

Methods: One hundred and ninety-six PD patients were enrolled in this study. Karnofsky Performance Status Scale(KPSS) scores were used to assess functional performance. Read More

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https://www.karger.com/Article/FullText/496081
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http://dx.doi.org/10.1159/000496081DOI Listing
January 2019
3 Reads

Preface - Advances in CKD 2019.

Blood Purif 2019 Jan 9:1-2. Epub 2019 Jan 9.

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http://dx.doi.org/10.1159/000495158DOI Listing
January 2019
1 Read

Could there be Haemodynamic Stress Effects on Pro-Inflammatory CD14+CD16+ Monocytes during Convective-Diffusive Treatments? A Prospective Randomized Controlled Trial.

Blood Purif 2019 Jan 2:1-10. Epub 2019 Jan 2.

Haematology Unit, Bone Marrow Transplant Center, Businco Hospital, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

Background: The main aim is to compare the pro-inflammatory CD14+CD16+ monocytes blood levels in patient in end-stage renal disease (ESRD) undergoing Mixed online Haemodiafiltration (Mixed OL-HDF) vs. post-dilution OL-HDF and online high-efficiency haemodialysis.

Methods: The study is a prospective double-blind randomized controlled cross-over trial. Read More

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http://dx.doi.org/10.1159/000494711DOI Listing
January 2019
1 Read

Patient-Centric User-Interface in Automated Peritoneal Dialysis: Impact on Training and Outcomes at a Single Center.

Blood Purif 2019 Jan 2:1-4. Epub 2019 Jan 2.

Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Background: AMIA cycler is a new automated peritoneal dialysis (APD) system, which was approved by FDA in 2015, which is more patient centric due to its features of voice guidance and touch screen. We retrospectively studied if these patient-centric features translated into better patient outcomes.

Methods: We compared 18 patients on AMIA cycler to 18 patients on conventional APD system. Read More

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https://www.karger.com/Article/FullText/495341
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http://dx.doi.org/10.1159/000495341DOI Listing
January 2019
4 Reads
1.920 Impact Factor

The Application Analysis of Multiplex Real-Time Polymerase Chain Reaction Assays for Detection of Pathogenic Bacterium in Peritoneal Dialysis-Associated Peritonitis.

Blood Purif 2019 Jan 2:1-9. Epub 2019 Jan 2.

Background/aims: To estimate the clinical value of bacterial detection in peritoneal dialysis-associated peritonitis (PDAP) by multiplex real-time polymerase chain reaction (RT-PCR). This study was undertaken to evaluate multiplex RT-PCR for identifying clinically significant bacteria in PDAP.

Methods: Seventy peritoneal dialysate specimens were collected and traditional bacterial culture and universal primer RT-PCR detection of the bacterial were used. Read More

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http://dx.doi.org/10.1159/000495780DOI Listing
January 2019
1 Read

Effect of Ionic Strength, pH and Chemical Displacers on the Percentage Protein Binding of Protein-Bound Uremic Toxins.

Blood Purif 2018 Dec 18:1-10. Epub 2018 Dec 18.

Background And Objectives: While trying to optimize the dialysis clearances of protein-bound uremic toxins (PBUTs), their percentage protein binding (% PB) is an important parameter. We evaluated the effects of ionic strength, pH change and chemical displacers on the dissociation of PBUTs from albumin in vitro.

Methods: PBUTs, such as 3-Carboxy-4-methyl-5-propyl-2-furan-propanoic acid (CMPF), p-cresylsulfate (PCS), indoxyl sulfate (IS) and indole-3-acetic acid (IAA), were spiked with human serum albumin (HSA) solution prepared with different Nacl concentrations and pH values or in the presence of a series of chemical displacers. Read More

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http://dx.doi.org/10.1159/000495343DOI Listing
December 2018
1 Read

The Effect of Citrate on Clot Formation, Dialyzer Reuse, and Anemia in Hemodialysis Patients.

Blood Purif 2018 Dec 13:1-8. Epub 2018 Dec 13.

Renal Unit, Department of Medical, Faculty of Medicine, Navamindradhiraj University, Bangkok, Thailand.

Background: Citrate anticoagulation is increasingly favored for preventing extracorporeal circuit clotting during renal replacement therapy. This study tested the effect of citrate compared with acetate on heparin avoidance and other parameters.

Methods: Sixty-one chronic hemodialysis (HD) patients were switched from conventional dialysis fluid (acetate) to citrate dialysis fluid and were treated in 3 phases, each lasting 4 weeks: 50%, 25%, and no heparin. Read More

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https://www.karger.com/Article/FullText/495025
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http://dx.doi.org/10.1159/000495025DOI Listing
December 2018
6 Reads

Different Effect of Hemodialysis on Function of Human Arterial and Venous Endothelial Cells.

Blood Purif 2018 Dec 13:1-5. Epub 2018 Dec 13.

Background/aims: Hemodialysis causes the systemic inflammatory response, which may affect the function of endothelial cells.

Methods: We studied the effect of the serum obtained after a hemodialysis session, compared to serum collected before the start of the treatment, on the gene expression and secretory activity of arterial endothelial cells (AECs) and venous endothelial cells (VECs) in in vitro culture.

Results: Serum collected at the end of the hemodialysis session increased expression of the studied genes in VECs, and at the same time decreased their expression in AECs. Read More

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http://dx.doi.org/10.1159/000495342DOI Listing
December 2018
1 Read

Tracking Arteriovenous Fistula Maturation: A Novel Approach.

Blood Purif 2018 Dec 6:1-6. Epub 2018 Dec 6.

Renal Research Institute, New York, New York, USA.

Background: The time between the creation of an arteriovenous fistula (AVF) and its successful use is significantly longer in hemodialysis (HD) patients in the United States compared to those in other countries, and there is an urgent need to reduce the residence time of central-venous catheters (CVC).

Methods: Successful AVF creation and maturation results in typical hemodynamic changes, such as an increase in cardiac output and upper body blood flow (UBBF). In patients with CVC as vascular access, we measured once per minute intradialytic central-venous oxygen saturation (ScvO2) and hemoglobin levels simultaneously using the Crit-Line Monitor. Read More

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http://dx.doi.org/10.1159/000494742DOI Listing
December 2018
18 Reads

Impact of Hybrid Therapy Comprising Peritoneal Dialysis and Hemodialysis on Acute Cardiovascular Events.

Blood Purif 2018 Dec 6:1-7. Epub 2018 Dec 6.

Background: The impact of hybrid therapy comprising peritoneal dialysis (PD) and hemodialysis on cardiovascular events in PD patients remains unclear.

Objective: We aimed to evaluate the effect of hybrid therapy on cardiovascular events.

Methods: A total of 93 PD patients undergoing hybrid therapy for ≥3 years were divided into 2 groups according to left ventricular ejection fraction (LVEF): lower ejection fraction (LEF [n = 29], LVEF < 60%) and normal ejection fraction (NEF [n = 64], LVEF ≥60%). Read More

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http://dx.doi.org/10.1159/000495357DOI Listing
December 2018
8 Reads

Virtual Reality Simulation in Peritoneal Dialysis Training: The Beginning of a New Era.

Blood Purif 2018 Dec 6:1-5. Epub 2018 Dec 6.

Weltenmacher GmbH, VR Training-Application, Düsseldorf, Germany.

Background/aim: Peritonitis rates in peritoneal dialysis (PD) vary considerably not only across countries but also between centers in the same country. Patient education has been shown to significantly reduce infection rates but up till now training lacks standardization with patients being trained using different methods and media (e.g. Read More

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https://www.karger.com/Article/FullText/494595
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http://dx.doi.org/10.1159/000494595DOI Listing
December 2018
25 Reads

Difficult Patient Behavior in Dialysis Facilities.

Blood Purif 2018 Dec 6:1-5. Epub 2018 Dec 6.

Difficult behavior exhibited by dialysis patients is a spectrum that includes nonadherence, verbal or physical abuse, and threatening acts. Such behaviors may lead to harmful consequences to the patient, other patients, the facility, and staff and can culminate in involuntary discharge. It is important to recognize that these "difficult behaviors" may be due to underlying psychosocial or medical issues, which places an onus on care providers to explore further. Read More

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https://www.karger.com/Article/FullText/494592
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http://dx.doi.org/10.1159/000494592DOI Listing
December 2018
8 Reads

Association of Central Venous Oxygen Saturation Variability and Mortality in Hemodialysis Patients.

Blood Purif 2018 Dec 6:1-8. Epub 2018 Dec 6.

Renal Research Institute, New York, New York,

Background: Central venous oxygen saturation (ScvO2) is correlated with cardiac output. In most patients, ScvO2 declines during hemodialysis (HD) due to factors such as reduced preload, myocardial stunning, and intermittent arrhythmias. Previous research has shown that low ScvO2 is associated with higher mortality in chronic HD patients. Read More

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http://dx.doi.org/10.1159/000494630DOI Listing
December 2018
9 Reads

Direct Effect of Septic Plasma in Human Cell Lines Viability.

Blood Purif 2018 Dec 6:1-7. Epub 2018 Dec 6.

Department of Nephrology, Dialysis and Transplant, San Bortolo Hospital, Vicenza, Italy.

Background: Sepsis is a life-threatening condition often associated with a high incidence of multiple organs injury. Several papers suggested the immune response by itself, with the production of humoral inflammatory mediators, is crucial in determining organ injury. However, little is known of how sepsis directly induces organ injury at the cellular levels. Read More

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https://www.karger.com/Article/FullText/494597
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http://dx.doi.org/10.1159/000494597DOI Listing
December 2018
12 Reads

Sickle Cell Nephropathy in the Pediatric Population.

Blood Purif 2018 Dec 5:1-9. Epub 2018 Dec 5.

Division of Nephrology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts,

Background: Compared to the past, patients with sickle cell disease (SCD) currently live longer due to improvements in diagnosis and comprehensive care. Due to these advances, long-term chronic complications pose a greater challenge in the management of patients with SCD. In particular, sickle cell nephropathy (SCN) is associated with significant morbidity and mortality across all age groups. Read More

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https://www.karger.com/Article/FullText/494581
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http://dx.doi.org/10.1159/000494581DOI Listing
December 2018
14 Reads

Dialysate Calcium Levels: Do They Matter?

Blood Purif 2018 Dec 5:1-6. Epub 2018 Dec 5.

Department of Internal Medicine, Division of Nephrology, Maastricht University Medical Center, Maastricht, The Netherlands.

Background: Calcium (Ca) is an essential element that plays a critical role in many biological processes. In dialysis patients, the regulation of Ca balance is highly complex, given the absence of kidney function, endocrine disturbances and the use of drugs such as phosphate binders, vitamin D analogues, and calcimimetics. Also, the use of different dialysate Ca (DCa) baths has profound effect on Ca balance, which depends both on the difference between the Ca concentration in the bath and the serum of the patients, as on the ultrafiltration volume. Read More

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https://www.karger.com/Article/FullText/494584
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http://dx.doi.org/10.1159/000494584DOI Listing
December 2018
12 Reads

Disaster Management in a Nephrology Service: Lessons Learned from Hurricane Maria.

Blood Purif 2018 Dec 5:1-6. Epub 2018 Dec 5.

Background: Puerto Rico suffered a major humanitarian -crisis after Hurricane Maria. We describe our experience with patients with renal disease in an academic medical center.

Summary: A comprehensive emergency response plan should be developed, shared and discussed with the team and the patients prior to the hurricane. Read More

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https://www.karger.com/Article/FullText/494580
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http://dx.doi.org/10.1159/000494580DOI Listing
December 2018
15 Reads

Best Vascular Access in the Elderly: Time for Innovation?

Blood Purif 2018 Dec 5:1-4. Epub 2018 Dec 5.

Division of Nephrology, Salisbury VA Health System, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.

Background: Conflicting data continue to surround the optimal dialysis access for the elderly. Many propose that catheters are the best option for this population; others emphasize the creation of an arteriovenous fistula.

Summary: While an arteriovenous access is the best available access, it has a high early failure rate, particularly in the elderly. Read More

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https://www.karger.com/Article/FullText/494591
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http://dx.doi.org/10.1159/000494591DOI Listing
December 2018
13 Reads

Body Fluids in End-Stage Renal Disease: Statics and Dynamics.

Blood Purif 2018 Dec 5:1-7. Epub 2018 Dec 5.

Background: Abnormalities in fluid status in hemodialysis (HD) patients are highly prevalent and are related to adverse outcomes.

Summary: The inherent discontinuity of the HD procedure in combination with an often compromised cardiovascular response is a major contributor to this phenomenon. In addition, systemic inflammation and endothelial dysfunction are related to extracellular fluid overload (FO). Read More

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https://www.karger.com/Article/FullText/494583
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http://dx.doi.org/10.1159/000494583DOI Listing
December 2018
10 Reads

End-Stage Kidney Patients Require Hemodialysis Therapy Full Start.

Blood Purif 2018 Dec 5:1-9. Epub 2018 Dec 5.

Recently the concept that prescription of chronic hemodialysis (HD) start should be tailored based on residual renal function (RRF) and urine output (UO) has been revived from the past and called infrequent or incremental dialysis. It mainly consists in prescribing 1 or 2 HD sessions per week instead of what has become the standard thrice-weekly HD. It is both surprising and fascinating that almost 60 years after the first end-stage kidney disease patient was treated by Scribner et al. Read More

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https://www.karger.com/Article/FullText/494582
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http://dx.doi.org/10.1159/000494582DOI Listing
December 2018
11 Reads

Recognizing Common Skin and Soft Tissue Infections in the Nephrology Clinic.

Blood Purif 2018 Dec 5:1-6. Epub 2018 Dec 5.

Renal failure patients have an increased risk of infection, including skin and soft tissue infections. This increased susceptibility is multifactorial, due to the conditions causing the renal failure as well as complications of treatment and renal failure's innate effects on patient health. These infections have a significant impact on patient morbidity, increased hospital and procedural demands, and the cost of health care. Read More

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http://dx.doi.org/10.1159/000494594DOI Listing
December 2018
12 Reads

Risk Factors of Central Venous Catheter-Related Bloodstream Infection for Continuous Renal Replacement Therapy in Kidney Intensive Care Unit Patients.

Blood Purif 2018 Nov 28:1-8. Epub 2018 Nov 28.

Background: The incidence of central venous catheter-related bloodstream infection (CRBSI) for continuous renal replacement therapy (CRRT) in kidney intensive care unit (ICU) patients is worthy of particular attention and recently, we analyzed clinical characteristics and risk factors of CRBSI for CRRT in our kidney ICU patients.

Methods: To be part of this retrospective study, 1,523 patients who had a central venous catheter (CVC) for CRRT during the period April 2010 to May 2015 in our centre were enrolled. The clinical features and pathogens of CRBSI patients were investigated. Read More

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http://dx.doi.org/10.1159/000495024DOI Listing
November 2018
4 Reads

Increased Frequency of In-Center Hemodialysis as Rescue Therapy: Impact on Hospitalization for Acute Cardiovascular Events.

Blood Purif 2018 Nov 22:1-8. Epub 2018 Nov 22.

Department of Artificial Organs, Akane-Foundation, Tsuchiya General Hospital, Hiroshima, Japan.

Background: The intermittency of conventional hemodialysis (HD) leads to an increase in cardiovascular events.

Objective: We aimed to evaluate the effect of in-center frequent HD (FHD, 4-6 times a week) as a rescue option for cardiovascular events.

Method: Patients who failed to achieve fluid volume control with conventional HD (thrice a week) were administered FHD. Read More

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http://dx.doi.org/10.1159/000495023DOI Listing
November 2018
1 Read

The Association of Longitudinal Serum Uric Acid and All-Cause Mortality in Incident Peritoneal Dialysis Patients.

Blood Purif 2018 Nov 21:1-8. Epub 2018 Nov 21.

Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan.

Background: Time-averaged uric acid (TA-UA) value was calculated to investigate the association of longitudinal UA and all-cause mortality in incident peritoneal dialysis (PD) patients.

Methods: Three hundred PD patients were divided into 3 groups based on the serum TA-UA level (Group 1: < 6 mg/dL; Group 2: 6-8 mg/dL; Group 3: ≥8 mg/dL). Hazards ratio (HR) of all-cause mortality was calculated. Read More

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http://dx.doi.org/10.1159/000494987DOI Listing
November 2018
8 Reads

Cycles, Arrows and Turbulence: Time Patterns in Renal Disease, a Path from Epidemiology to Personalized Medicine?

Blood Purif 2018 Nov 16:1-14. Epub 2018 Nov 16.

Renal Research Institute, New York, New York, USA.

Patients with end-stage renal disease (ESRD) experience unique patterns in their lifetime, such as the start of dialysis and renal transplantation. In addition, there is also an intricate link between ESRD and biological time patterns. In terms of cyclic patterns, the circadian blood pressure (BP) rhythm can be flattened, contributing to allostatic load, whereas the circadian temperature rhythm is related to the decline in BP during hemodialysis (HD). Read More

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https://www.karger.com/Article/FullText/494827
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http://dx.doi.org/10.1159/000494827DOI Listing
November 2018
17 Reads

Comparison of the Accuracy of the Novel PrisMax Continuous Renal Replacement Therapy System to the Classic Prismaflex System.

Blood Purif 2018 Nov 14:1-5. Epub 2018 Nov 14.

Department of Nephrology, St Bortolo Hospital, Vicenza, Italy.

Background/aims: We assessed how the novel PrisMax continuous renal replacement therapy (CRRT) system performed in an international multicentre setting. The system has multiple novel tools aiming to increase accuracy and dose delivery.

Methods: Data was prospectively collected from 7 intensive care units in 6 countries. Read More

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https://www.karger.com/Article/FullText/494764
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http://dx.doi.org/10.1159/000494764DOI Listing
November 2018
16 Reads

Continuous Veno-Venous Hemodialysis Using the Cardio-Renal Pediatric Dialysis Emergency MachineTM: First Clinical Experiences.

Blood Purif 2018 Oct 31:1-7. Epub 2018 Oct 31.

Department of Nephrology, Dialysis, and Transplantation, International Renal Research Institute, San Bortolo Hospital, Vicenza, Italy.

We report the first worldwide experience with continuous veno-venous hemodialysis (CVVHD) in children using the last generation Cardio-Renal Pediatric Dialysis Emergency Machine (CARPEDIEM)TM device. Thirteen children received 1,008 h of CVVHD during 95 sessions, using a 0.15 (n = 7) or a 0. Read More

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https://www.karger.com/Article/FullText/494437
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http://dx.doi.org/10.1159/000494437DOI Listing
October 2018
14 Reads
1.920 Impact Factor

Survival and Clinical Outcomes of Tunneled Central Jugular and Femoral Catheters in Prevalent Hemodialysis Patients.

Blood Purif 2018 Oct 25:1-8. Epub 2018 Oct 25.

Background: The literature on the outcomes of tunneled femoral catheters compared to that of jugular catheters is scarce and derived mainly from small cohorts.

Material And Methods: Seven hundred and sixty six catheters were placed in 673 hemodialysis patients, 622 in the jugular/subclavian veins and 144 in the femoral veins. Patients were followed prospectively for 36 months. Read More

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https://www.karger.com/Article/FullText/494206
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http://dx.doi.org/10.1159/000494206DOI Listing
October 2018
16 Reads

Plasmapheresis Combined with Continuous Plasma Filtration Adsorption Rescues Severe Acute Liver Failure in Wilson's Disease before Liver Transplantation.

Blood Purif 2018 Oct 25:1-6. Epub 2018 Oct 25.

Wilsonian crisis (hemolytic crisis and acute liver failure [ALF] in Wilson's disease) is fatal and almost all patients ultimately need a timely liver transplantation to save their lives. How to safely pass the critical period to liver transplantation is still a big challenge to doctors especially to pediatricians facing more difficult situations in blood purification. Here, we report about a 7-year-old child (weight 21 kg) presenting with severe hemolysis and impending ALF that made a rapid recovery with prompt initiation of plasmapheresis combined with continuous plasma filtration adsorption (CPFA) and chelation therapy. Read More

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http://dx.doi.org/10.1159/000493909DOI Listing
October 2018
10 Reads

Presepsin and Procalcitonin Levels as Markers of Adverse Postoperative Complications and Mortality in Cardiac Surgery Patients.

Blood Purif 2018 Oct 18:1-9. Epub 2018 Oct 18.

IRRIV - International Renal Research Institute Vicenza, Vicenza, Italy.

Backgound: This study was aimed at evaluating the presepsin and procalcitonin levels to predict adverse postoperative complications and mortality in cardiac surgery patients.

Methods: A total of 122 cardiac surgery patients were enrolled for the study. Presepsin and procalcitonin levels were measured 48 h after the procedure. Read More

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http://dx.doi.org/10.1159/000494207DOI Listing
October 2018
3 Reads
1.920 Impact Factor

Is Expanded Hemodialysis an Option to Online Hemodiafiltration for Small- and Middle-Sized Molecules Clearance?

Blood Purif 2018 Oct 12:1-6. Epub 2018 Oct 12.

Department of Nephrology, Hospital General Universitario of Castellón, Castellón, Spain.

Background: Recent evidence suggests a better reduction rate of some uremic toxins with expanded hemodialysis (HDx).

Methods: Prospective study including 8 hemodialysis patients. We divided the study in 2 phases; within the first one, we assigned 4 patients (group 1) to undergo online hemodiafiltration with a PF 210H dialyzer, and the other 4 patients (group 2) to undergo HDx with the high retention onset Theranova 500 dialyzer during 24 sessions. Read More

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October 2018
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Introduction to Extracorporeal Multiple Organ Support.

Blood Purif 2018 Oct 10:1-2. Epub 2018 Oct 10.

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http://dx.doi.org/10.1159/000492380DOI Listing
October 2018
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Calculating Standard Kt/V during Hemodialysis Based on Urea Mass Removed.

Blood Purif 2018 Oct 8:1-7. Epub 2018 Oct 8.

Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

Background/aims: We derived a novel equation for calculating weekly urea standard Kt/V (stdKt/V) during hemodialysis (HD) based on urea mass removed, comparable to the approach during peritoneal dialysis.

Methods: Theoretical consideration of urea mass balance during HD led to the following equation for stdKt/V, namely, stdKt/V = N × (URR + UFV/V), where N is the number of treatments per week, URR is urea reduction ratio per treatment, UFV is ultrafiltration volume per treatment, and V is postdialysis urea distribution volume. URR required corrections for postdialysis rebound and intradialytic urea generation. Read More

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https://www.karger.com/Article/FullText/493178
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http://dx.doi.org/10.1159/000493178DOI Listing
October 2018
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Effect of Increased Convection Volume by Mid-Dilution Hemodiafiltration on the Subclinical Chronic Inflammation in Maintenance Hemodialysis Patients.

Blood Purif 2018 Oct 5:1-9. Epub 2018 Oct 5.

University of Campania "Luigi Vanvitelli", Naples, Italy.

Mid-dilution hemodiafiltration (MID) is a dialytic technique that might improve systemic inflammation of patients in chronic hemodialysis (HD) by increasing substitution volumes. To verify this hypothesis, we performed a prospective cross-over study comparing the effect on inflammatory biomarkers of higher convection by MID versus standard convection by post-dilution hemodiafiltration (HDF). Patients under chronic HD were therefore treated by MID and HDF by crossover design. Read More

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http://dx.doi.org/10.1159/000492377DOI Listing
October 2018
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International Survey on the Management of Acute Kidney Injury and Continuous Renal Replacement Therapies: Year 2018.

Blood Purif 2018 Sep 28:1-7. Epub 2018 Sep 28.

IRRIV-International Renal Research Institute, Vicenza, Italy.

Introduction: Definition, prevention, and management of acute kidney injury (AKI) and the optimal prescription and delivery of renal replacement therapy (RRT) are currently matters of ongoing discussion. Due to the lack of definitive published literature, a wide gap might exist between routine clinical practice and available recommendations. The aim of this survey was to explore the clinical approach to AKI and RRT in a broad population of nephrologists and intensivists participating in the 36th International course on AKI and Continuous RRT (CRRT), held in Vicenza in June 2018. Read More

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http://dx.doi.org/10.1159/000493724DOI Listing
September 2018
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The Incidence Prognosis and Risk Factors of Cognitive Impairment in Maintenance Haemodialysis Patients.

Blood Purif 2018 Sep 25:1-8. Epub 2018 Sep 25.

Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Objective: To investigate the incidence and the prognosis of cognitive impairment (CI) and to find out the risk factors associated with the outcome in maintenance haemodialysis (MHD) patients.

Methods: Enrolled the patients who met the criteria as below: MHD (≥3 months) patients before July 2014, ≥18 years old and could carry on the cognitive function test (Montreal Cognitive Assessment [MoCA]). All enrolled patients were divided into 2 groups: CI group (MoCA < 26) and non-CI group (MoCA ≥26). Read More

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http://dx.doi.org/10.1159/000493524DOI Listing
September 2018
2 Reads
1.920 Impact Factor