2 results match your criteria Blood Cells Molecules And Diseases[Journal]

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Immunological Features in the Process of Blood Platelet-Induced Alloimmunisation, with a Focus on Platelet Component Transfusion.

Diseases 2019 Jan 14;7(1). Epub 2019 Jan 14.

Établissement Français du Sang Auvergne-Rhône-Alpes, 69150 Décines, France.

Alloimmunisation to platelet antigens is not uncommon; a large number of females, having had pregnancies, developed antibodies to Human Leukocyte Antigen (HLA) moieties harboured on their foetuses' cells (inherited from the father(s)) that may conflict with further pregnancies and transfused Platelet Components occasionally. This is possible since platelets constitutionally express HLA class I molecules (though in copy numbers that consistently differ among individuals). Platelets also express HPA moieties that are variants of naturally expressed adhesion and aggregation molecules; HPA differences between mothers and foetuses and between donors and recipients explain alloimmune conflicts and consequences. Read More

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http://dx.doi.org/10.3390/diseases7010007DOI Listing
January 2019
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Levels of Soluble Endothelium Adhesion Molecules and Complications among Sickle Cell Disease Patients in Ghana.

Diseases 2018 04 21;6(2). Epub 2018 Apr 21.

Department of Haematology, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.

Background: Soluble adhesion molecules are involved in the gathering and joining of inflammatory cells to vascular endothelium. Therefore, they serve as potential markers of endothelial dysfunction in vascular diseases including sickle cell disease (SCD). In Ghana, there are scarcely any report on the levels of adhesion molecules among SCD patients. Read More

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http://dx.doi.org/10.3390/diseases6020029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023299PMC
April 2018
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