Grey Matter Microstructural Integrity Alterations in Blepharospasm Are Partially Reversed by Botulinum Neurotoxin Therapy.
- Hanganu Alexandru,
- Muthuraman Muthuraman,
- Venkata Chaitanya Chirumamilla,
- Nabin Koirala,
- Burcu Paktas,
- Günther Deuschl,
- Kirsten E Zeuner,
- Sergiu Groppa
PLoS One 2016 16;11(12):e0168652. Epub 2016 Dec 16.
Department of Neurology, University of Kiel, Kiel, Germany.
Objective: Benign Essential Blepharospasm (BEB) and hemifacial spasm (HFS) are the most common hyperkinetic movement disorders of facial muscles. Although similar in clinical presentation different pathophysiological mechanisms are assumed. Botulinum Neurotoxin (BoNT) is a standard evidence-based treatment for both conditions. Read More