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Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Mar;54(3):187-191

Department of Otorhinolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education(Capital Medical University), Beijing 100730, China.

To discuss the clinical and radiological features of IgG4-related rhinosinusitis. In this retrospective research, the clinical data of 16 patients diagnosed with IgG4 related rhinosinusitis, who were enrolled in Beijing Tongren Hospital from November 2013 to September 2017, were collected. The clinical features, laboratory findings, radiological findings, histological features, treatment and prognosis were all summarized. Read More

BMC Ophthalmol 2019 Mar 7;19(1):67. Epub 2019 Mar 7.

Department of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Xuhui District, Shanghai, 200031, China.

Background: To evaluate the ocular surface characteristics and the infestation of Demodex in Chinese paediatric and adult blepharokeratoconjunctivitis (BKC).

Methods: Fifty consecutive patients with BKC and 50 age- and sex-matched healthy subjects were enrolled. Lid margin characteristics and corneal disorders were evaluated under slit-lamp illumination. Read More

Clin Ophthalmol 2019 22;13:189-198. Epub 2019 Jan 22.

Clinical Trials Section, Central Eye Care, Arlington Heights, IL, USA,

Purpose: Evaluation of the safety and effectiveness of a TearCare retreatment in adult subjects with clinically significant dry eye disease (DED).

Patients And Methods: This was an extension of an initial 6-month, prospective, single-center, randomized, parallel-group pilot study. In the initial study, subjects with DED were randomized to either a single TearCare treatment or 4 weeks of daily warm compress therapy. Read More

Graefes Arch Clin Exp Ophthalmol 2019 Apr 21;257(4):785-790. Epub 2019 Jan 21.

Save Sight Institute, University of Sydney, Sydney Eye Hospital Campus, 8 Macquarie Street, Sydney, NSW, 2000, Australia.

Purpose: 3-Hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR), the rate-limiting enzyme of cholesterol production, has been found to contribute to lipid secretion from skin sebaceous glands and hair follicles. We assessed for HMGCR expression in human eyelid tissue and in immortalized human meibomian gland epithelial cells (HMGECs) using immunohistochemistry.

Methods: Full thickness human eyelid specimens in archival paraffin blocks were obtained. Read More

Clin Ophthalmol 2018 14;12:2629-2636. Epub 2018 Dec 14.

Ophthalmology Department, Paris Nord Val-de-Seine University Hospitals, Hôpital Bretonneau, Tours, France.

Background: Dry eye disease (DED) is characterized by a loss of homeostasis of the tear film. It goes along with ocular symptoms, in which ocular surface inflammation and damage play etiological roles. High-mobility group box 1 protein (HMGB1) is a pro-inflammatory protein found in the tear fluid during conjunctivitis, blepharitis and DED. Read More

Cornea 2019 Feb;38(2):146-150

Ophthalmic Research Center, Department of Ophthalmology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: To investigate the rate and agents of contamination in bandage soft contact lenses fitted for management of persistent corneal epithelial defects.

Methods: This prospective comparative case series enrolled 57 consecutive eyes fitted with bandage contact lenses for treatment of persistent corneal epithelial defects. The lenses were collected at the time of epithelial closure or when it was necessary to exchange contact lenses and were immediately placed in sterile tubes containing an enriched thioglycolate liquid medium. Read More

Biol Pharm Bull 2018 ;41(11):1694-1700

Department of Digestive Surgery, Kyoto Okamoto Memorial Hospital.

Paclitaxel and nanoparticle albumin-bound paclitaxel are known to cause adverse events of eye disorders, such as cystoid macular edema. However, at present, the risk factors remain unclear. Therefore, risk factors for eye disorders caused by paclitaxel and nanoparticle albumin-bound paclitaxel were studied. Read More

Jpn J Ophthalmol 2018 Nov 25;62(6):628-633. Epub 2018 Sep 25.

Department of Microbiology, Wroclaw Medical University, Chalubinskiego Street 4, 50-368, Wrocław, Poland.

Purpose: Two Demodex species (eyelash mites)-D. folliculorum and D brevis-are believed to be associated with human skin and eye diseases. However, the clinical significance of infection with Demodex species remains controversial. Read More

Indian J Public Health 2018 Jul-Sep;62(3):239-241

Assistant Professor, Department of Ophthalmology, Hamdard Institute of Medical Sciences and Research, Hamdard University, New Delhi, India.

In humans, Pthirus pubis or crab louse usually infests hair of pubic region. Phthiriasis palpebrarum (infestation of the eyelashes and eyelids) is not as rare as is reported in literature, especially in low socioeconomic communities. It is possible that the disease is being perhaps missed due to its clinical similarity with anterior blepharitis. Read More

Eur J Gastroenterol Hepatol 2018 12;30(12):1502-1506

Department of Ophthalmology, Martin Luther University Halle-Wittenberg, Halle, Germany.

Objective: Ocular manifestations of inflammatory bowel disease (IBD) are relevant complications of IBD. Only a few prospective studies are available on the characteristics of these manifestations. The aim of this study was to characterize the frequency of eye disease in patients with IBD, including primary and secondary ocular manifestations of IBD, and to identify patients who may need specialized ophthalmologic care. Read More

Can J Ophthalmol 2018 08 11;53(4):e149-e151. Epub 2017 Dec 11.

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Turkiye Parazitol Derg 2018 Jun;42(2):130-133

İstanbul Medipol Üniversitesi, Göz Hastalıkları Anabilim Dalı, İstanbul, Türkiye.

Objective: Demodex acari is an obligate ectoparasite, and it is usually located in the human hair follicles, eyelash roots, and sebaceous glands. The aim of this study was to investigate the presence of Demodex infestation in chronic blepharitis cases that are resistant to therapy.

Methods: Patients who were admitted at the Istanbul Medipol University School of Medicine Hospital with a diagnosis of chronic blepharitis were included. Read More

Arch Soc Esp Oftalmol 2018 Oct 19;93(10):476-480. Epub 2018 Jul 19.

Departamento de Bioquímica Aplicada, Facultad de Química, UNAM, Coyoacán, Ciudad de México, México. Electronic address:

Objective: To determine the relationship between the components of the metabolic syndrome with the presence of blepharitis.

Methods: The study included 60 patients with a diagnosis of blepharitis and 30 control subjects. Anthropometric measurements and blood pressure were recorded, and peripheral venous blood samples were obtained under fasting conditions to determine the concentration of Glucose, Cholesterol, and Triglycerides. Read More

J Optom 2018 Oct - Dec;11(4):232-241. Epub 2018 Jul 17.

Centre for Contact Lens Research, School of Optometry& Vision Science University of Waterloo, 200 University Avenue West, Waterloo, ON, Canada.

Purpose: Diagnostic testing for dry eye disease (DED) in Sjogren's syndrome (SS) is well described. Little is published about monitoring this systemic autoimmune DED. We analyzed the SS related DED tests used in North American optometric practices and compared academic settings to private practice settings. Read More

Int J Dermatol 2018 Dec 26;57(12):1437-1438. Epub 2018 Jun 26.

Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium.

Eye Contact Lens 2018 Nov;44(6):e25-e26

Department of Ophthalmology, Diskapi Yildirim Beyazit Education and Training Hospital, University of Health Sciences, Ankara, Turkey.

Demodex is an important pathogen in ophthalmology. It is believed to cause a variety of eyelid and eyelash diseases. Currently, light microscopes are being used for imaging demodex. Read More

Eye Contact Lens 2019 Jan;45(1):61-66

Department of Ophthalmology, (B.Y., M.C.M., S.K., M.I.), Hacettepe University, Ankara, Turkey; and Department of Pediatrics (Ç.T.), Division of Immunology, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Objectives: To determine whether silicone hydrogel (SH) contact lens (CL) use, with or without meibomian gland dysfunction (MGD), promotes ocular surface inflammation.

Methods: Subjects wearing SH-CL for at least 6 months who also had coexisting MGD (group 1, n=20), SH-CL users who did not have MGD (group 2, n=20), patients who had MGD but did not use CL (group 3, n=20), and healthy CL-naive individuals with no known systemic or ocular diseases (group 4, n=20) were included in this cross-sectional, single-center study. All subjects underwent tear function tests consisting of tear break-up time (tBUT), ocular surface staining, Schirmer test, and the Ocular Surface Disease Index (OSDI) questionnaire, as well as determination of tear IL-1RA, IL-1β, IL-2, IL-2R, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12, IL-13, IL-15, IL-17, IFN-α, IFN-γ, TNF-α, granulocyte-macrophage colony-stimulating factor, IP-10, monokine induced by gamma interferon, RANTES, eotaxin, MIP-1α, MIP-1β, and MCP-1 levels using Luminex multicytokine immunobead assay. Read More

Mikrobiyol Bul 2018 Apr;52(2):214-220

Selçuk University Faculty of Veterinary, Department of Parasitology, Konya, Turkey.

Demodicosis is an ectoparasitic cutaneous infestation of pilosebaceous unit caused by Demodex mites. Demodex spp. are considered to be pathogenic when they increase in number and infect dermis. Read More

Arq Bras Oftalmol 2018 Jun;81(3):219-225

Dermatology Department, Universidade do Estado do Pará, Belém, PA, Brazil.

Purpose: We aimed to report the ocular manifestations observed in patients with psoriasis.

Methods: Patients were included and referred to our ophthalmology clinic from dermatology clinics of Universidade do Estado do Pará between October 2013 and August 2014. Clinical interviews were conducted to identify relevant epidemiological data, clinical features, and treatment details, and data were recorded using the same protocol. Read More

Ophthalmic Res 2018 6;60(2):109-114. Epub 2018 Jun 6.

Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Multi-Centric Residency Program in Ophthalmology, Monterrey, Mexico.

Aims: The purpose of this paper was to determine the lacrimal concentration of IL-1α and MMP-9 in patients with active ocular rosacea before and after systemic treatment with azithromycin or doxycycline.

Methods: After 4 weeks of therapy with azithromycin (500 mg/day, 3 days a week PO) or doxycycline (200 mg/day PO), lacrimal samples were analyzed using an enzyme-linked immunosorbent assay multiplex.

Results: There was a significant difference between baseline IL-1α (37. Read More

Turkiye Parazitol Derg 2018 Mar;42(1):90-92

Dünyagöz Hospital, Bursa, Turkey.

A six-year-old male patient was admitted to our hospital due to itching and scalding crusts that persisted 10-15 days in both eyes. Upon biomicroscopic examination, 5-6 semi-translucent, yellowish brown living lice attached to the upper eyelashes and a large number of eggs were observed. Following application of pilocarpine hydrochloride (Pilomann 2%, Bausch-Lomb) and topical proparacaine hydrochloride (Alcaine 0. Read More

Dermatol Ther 2018 Jul 23;31(4):e12609. Epub 2018 Apr 23.

Dermatology department, University Hospital of Paracelsus, Medical University of Salzburg, Salzburg, Austria.

Morbihan's disease is characterized by chronic persistent facial edema of the upper half of the face, absence of typical diagnostic findings, and refractoriness to treatment. A 44-year-old man was diagnosed with Morbihan's disease based on clinical signs and histopathology, which showed dermal edema in upper dermis, discrete lymphocytic infiltrate without granulomatous reaction, and mast cell infiltration. After long-term therapy with intralesional triamcinolone a remarkable objective and subjective clinical response was observed. Read More

Acta Ophthalmol 2018 Sep 15;96(6):e707-e711. Epub 2018 Apr 15.

Department of Ophthalmology, Medical University of Graz, Graz, Austria.

Purpose: The purpose of this study was to assess the prevalence of meibomian gland dysfunction (MGD) and its association with tear film and ocular surface parameters in an Austrian clinical population of dry eye patients.

Methods: The records of 1372 consecutive patients from a dry eye unit were analysed retrospectively. Symptoms and objective tear film and ocular surface parameters were evaluated. Read More

J Fr Ophtalmol 2018 Mar 19;41(3):224-230. Epub 2018 Mar 19.

Unité de pneumo-allergologie de l'enfant, pôle pédiatrique Pr-Labbé, CHU de Clermont-Ferrand-Estaing, 1, rue Lucie-Aubrac, 63100 Clermont-Ferrand, France. Electronic address:

Allergies are frequently implicated in ophthalmologic practice. These typically benign allergies can be potentially severe for the ocular surface and have an impact in everyday life. We relate, through a case of keratoconjunctivitis involving 2 types of hypersensitivity, the various triggers and therapeutic choices to allow a more effective treatment. Read More

PLoS One 2018 21;13(2):e0193161. Epub 2018 Feb 21.

Ophthalmology department, Chiang Mai University Hospital, Chiang Mai, Thailand.

Human immunodeficiency virus (HIV) causes impairment to the human immune system which leads to immunocompromised conditions, including ocular complications. Several important HIV-associated disorders may involve the anterior segment, ocular surface, and adnexae organ such as dry eye, blepharitis which reduce quality of life of patients. In present, potent antiretroviral therapies HAART (highly active antiretroviral therapy) has improved the length and quality of life which may lead to an increased prevalence of anterior segment ocular disorders. Read More

Cornea 2018 Apr;37(4):442-447

Cornea Department, Fundación Oftalmológica Los Andes, Santiago, Chile.

Purpose: This study describes ophthalmologic and systemic clinical findings in different subtypes of epidermolysis bullosa (EB) establishing genotype-phenotype correlations.

Methods: A cross-sectional study was conducted in 58 patients with EB together with the Dystrophic Epidermolysis Bullosa Research Association, Chile. Data were stratified by major subtypes such as "simplex epidermolysis bullosa" (EBS), "junctional epidermolysis bullosa" (JEB), "recessive and dominant dystrophic epidermolysis bullosa" and "dominant dystrophic epidermolysis bullosa" (DDEB), and "Kindler syndrome" (KS). Read More

Int Ophthalmol 2019 Feb 29;39(2):405-417. Epub 2018 Jan 29.

The National Optometry Centre, Dublin Institute of Technology, Kevin Street, Dublin 8, Ireland.

Purpose: To investigate the prevalence of ocular Demodex folliculorum (DF) in an Irish population. To validate a modified Ocular Surface Disease Index questionnaire and employ it to evaluate the relationship between dry eye symptoms and the presence of DF.

Methods: One hundred and fifty-six subjects were enrolled in an epidemiological cross-sectional prevalence study. Read More

Health Qual Life Outcomes 2018 Jan 11;16(1):11. Epub 2018 Jan 11.

UCLA Department of Medicine, Division of General Internal Medicine & Health Services Research, 911 Broxton Avenue, Los Angeles, CA, 90024, USA.

Background: Blepharitis is an ocular surface disease and chronic ophthalmic condition. This paper reports on the development of psychometric evaluation of a patient-reported measure of blepharitis symptoms.

Methods: Self-reports of 13 blepharitis symptoms collected in a Phase 3 multi-site, randomized, double-masked, 4-arm parallel group, clinical trial of 907 individuals with blepharitis (mean age = 62, range: 19-93; 57% female) were analyzed. Read More

Indian J Ophthalmol 2018 01;66(1):36-38

Department of Ophthalmology, Hospital General Gea Gonzalez, Calzada de Tlalpan 4800, México.

Purpose: The objective of the study is to compare the frequency of Demodex on the eyelash follicle of patients with rosacea and referents without rosacea or ophthalmological disorders.

Methods: This is a comparative, open, observational, and cross-sectional study that included 41 patients diagnosed with rosacea and 41 referents without rosacea diagnosis or ophthalmic alterations. The individuals underwent a slit-lamp examination in which two eyelashes per eyelid were removed with fine forceps. Read More

Aerosp Med Hum Perform 2018 Jan;89(1):72-74

Kitz R. You're the flight surgeon: blepharitis. Aerosp Med Hum Perform. Read More

Med Sci Monit 2017 Dec 10;23:5862-5869. Epub 2017 Dec 10.

Department of Ophthalmology, Uludag University School of Medicine, Bursa, Turkey.

BACKGROUND Demodex may cause chronic and refractory blepharitis with associated ocular surface problems, and its diagnosis and treatment can be quite challenging. In this study, our aim was to assess the efficacy of tea tree oil in Demodex treatment on caucasian patients in an industrialized region of Turkey, and to develop a systematic scoring system for extremely accurate diagnosis in the absence of advanced facilities. MATERIAL AND METHODS Charts of 412 patients with blepharitis were reviewed. Read More

Ophthalmic Plast Reconstr Surg 2018 Mar/Apr;34(2):e52-e53

Ophthalmic Plastic Surgery, Ocular Oncology & Aesthetic Services, LV Prasad Eye Institute, Vijaywada, India.

Koebner phenomenon is the development of isomorphic pathologic lesions on a wound of a patient with preexisting cutaneous disease, most commonly psoriasis. An elderly male with palmoplantar psoriasis developed periocular psoriasis in the form of blepharitis and conjunctivitis following an external dacryocystorhinostomy as a manifestation of Koebner phenomenon. Immediate diagnosis and treatment with topical steroids led to complete recovery. Read More

Ophthalmic Genet 2018 04 28;39(2):268-270. Epub 2017 Nov 28.

c Center for Medical Genetics , Ghent University Hospital , Ghent , Belgium.

Background: To describe ocular and vascular findings in a patient with multiple endocrine neoplasia type 2B.

Materials And Methods: Case report of a 31-year-old male who was referred for ocular assessment following diagnosis of a carotid artery dissection and multiple vascular anomalies.

Results: Clinical examination revealed a marfanoid habitus, myelinated corneal nerve fibers, neuromas in the perilimbal area, conjunctival hyperemia with peripheral corneal neovascularization, and posterior blepharitis. Read More

Arq Bras Oftalmol 2017 Sep-Oct;80(5):296-299

Department of Ophthalmology, School of Medicine, Uludağ University, Bursa, Turkey.

Purpose: To estimate the prevalence of external punctal stenosis (EPS) in the elderly population and investigate associated factors.

Methods: A total of 278 patients ≥65 years of age were evaluated for evidence of EPS from January to July 2016. Associated systemic, ocular, demographic, and lifestyle factors were investigated. Read More

Br J Ophthalmol 2018 09 16;102(9):1283-1287. Epub 2017 Nov 16.

Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan.

Background: To investigate the relationship between blepharitis and metabolic syndrome (MetS) by using the Longitudinal Health Insurance Database (LHID) of Taiwan.

Methods: This retrospective cohort study was conducted using data collected from the LHID for the period from 2009 to 2013. This study enrolled patients who received a diagnosis of blepharitis according to the International Classification of Diseases, Ninth Revision, diagnostic code. Read More

Cont Lens Anterior Eye 2018 04 21;41(2):201-204. Epub 2017 Oct 21.

Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Laboratory, 17 Hou Gou Lane, Chong Nei Street, Beijing 100005, China. Electronic address:

Purpose: To describe the type of complications related to contact lens (CL) wear in a tertiary hospital in XX, China.

Methods: A retrospective study of 141 patients who complained discomfort after wearing contact lens on an outpatient basis of XX Hospital were conducted from the January 2012 to December 2015. The data included patients' demographics, lens type, history, slit-lamp examination, reports of corneal scrapings, culture, and examination of in vivo confocal microscopy. Read More

Eye Contact Lens 2018 Nov;44 Suppl 2:S87-S92

Centre for Contact Lens Research (W.N., L.J.), School of Optometry & Vision Science, University of Waterloo, Waterloo, ON, Canada; and École d'optométrie (E.B.), Université de Montréal, Montreal, Quebec, Canada.

Purpose: To quantify the discomfort over time of various eyelid cleansers against Demodex.

Methods: This was a prospective, randomized, controlled, crossover, open-label study that enrolled 26 participants. The cleansers used in this study were Biotissue Cliradex (CD), OCuSOFT Lid Scrubs Plus (OP), OCuSOFT OUST Demodex Swabstix (ODS), TheraTears Theralid (TT), NovaBay Avenova (NA). Read More

Cornea 2017 Dec;36(12):1567-1569

*Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan; †Department of Ophthalmology, Fukuchiyama City Hospital, Kyoto, Japan; ‡Oike-Ganka Ikeda Clinic, Kyoto, Japan; §Department of Ophthalmology, National Center for Geriatrics and Gerontology, Obu, Japan; and ¶Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Purpose: The primary side effects associated with 0.1% brimonidine tartrate (BT) ophthalmic solution with sodium chlorite are allergic conjunctivitis, blepharitis, and conjunctival hyperemia. However, cornea-related side effects are rare. Read More

J Ocul Pharmacol Ther 2017 11 18;33(9):678-685. Epub 2017 Sep 18.

12 Department of Ophthalmology, Ludwig Maximilian University , Munich, Germany .

Purpose: Meibomian gland disease is generally accepted as the leading cause for evaporative dry eye disease (DED). In a previous study, perfluorohexyloctane, a semifluorinated alkane, has been demonstrated to significantly increase tear film breakup time and to reduce corneal fluorescein staining in patients with evaporative DED, thereby vastly reducing dry eye-related symptoms. This study was set up to evaluate perfluorohexyloctane in a larger population of patients with Meibomian gland dysfunction. Read More

Curr Eye Res 2017 11 18;42(11):1440-1444. Epub 2017 Sep 18.

b Department of Ophthalmology , Santa Casa de Misericórdia de São Paulo , São Paulo , Brazil.

Purpose: This prospective, randomized, double-blind interventional case series was designed to evaluate the short-term efficacy of 0.03% tacrolimus ointment as a new therapeutic approach for refractory cases of posterior blepharitis.

Methods: Forty eyes (20 patients) with posterior blepharitis refractory to previous treatment were randomized. Read More

Am J Emerg Med 2017 Nov 7;35(11):1789.e3-1789.e5. Epub 2017 Aug 7.

Emergency Department, University Hospital of Bichat, AP-HP, Paris, France; Ilumens - Simulation laboratory, University of Paris-Diderot, Paris, France. Electronic address:

Background: Myiasis designates the infestation of live human and vertebrate animals with dipterous (two-winged) larvae (maggots) and is the fourth most common travel-associated skin disease. Furuncle is the most common aspect of cutaneous myiasis.

Case Presentation: A 24-year-old Caucasian female had been back from Cap-Vert. Read More

Orbit 2018 Feb 30;37(1):36-40. Epub 2017 Aug 30.

a Faculdade de Medicina de Botucatu , Universidade Estadual Paulista , Botucatu, Sao Paulo State , Brazil.

The purpose of this article is to analyze the outcomes of two surgical techniques to treat major trichiasis. A retrospective chart review of 67 patients (89 eyelids) with major trichiasis was performed who underwent surgical treatment using one of two techniques: intermarginal split lamella with graft (ISLG group) or lid lamella resection (LLR group). There were 30 lids in the ISLG group with mean patient age of 71. Read More

BMC Ophthalmol 2017 Aug 22;17(1):151. Epub 2017 Aug 22.

Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences (CMHS), University of Gondar (UOG), P.O. box 196, Gondar, Ethiopia.

Background: External ocular infection is a public health problem in Ethiopia. The aim of this study was to determine the prevalence and antimicrobial susceptibility pattern of external ocular bacterial infections.

Methods: A cross sectional study was conducted at the University of Gondar Hospital among patients seeking health services at the Department of Ophthalmology from January to April, 2016. Read More

Graefes Arch Clin Exp Ophthalmol 2017 Nov 24;255(11):2277-2285. Epub 2017 Jul 24.

Department of Ophthalmology, University Eye Hospital Bonn, University of Bonn, Ernst-Abbe Str. 2, 53127, Bonn, Germany.

Purpose: The purpose of the study was to evaluate the characteristics of sebaceous gland carcinoma (SGC) of the ocular adnexae, which is due to a high variability in clinical, histological and immunohistochemical characteristics often challenging to diagnose.

Methods: Records of six patients with SGC were reviewed, who underwent surgical excision and who were histologically diagnosed with SGC. For comparison, there were specimens from four patients with basal cell carcinoma (BCC) and four patients with squamous cell carcinoma (SCC). Read More

Graefes Arch Clin Exp Ophthalmol 2017 Oct 15;255(10):2009-2015. Epub 2017 Jul 15.

Department of Ophthalmology and Micro-technology, Yokohama City University School of Medicine, 4-57 Urafune-cho, Minami-ku, Yokohama, Kanagawa, 232-0024, Japan.

Purpose: The aim of this study was to evaluate the one-year efficacy, ability to lower intraocular pressure, and tolerability of ripasudil, a rho-kinase inhibitor, in patients with glaucoma inadequately controlled with maximum medical therapy.

Methods: This prospective, non-comparative, interventional case-series study included 39 patients with primary open-angle glaucoma inadequately controlled with maximum medical therapy before treatment with ripasudil. Ripasudil was administered twice per day as adjunctive therapy to ongoing glaucoma treatment. Read More

Prim Care Diabetes 2017 10 23;11(5):421-429. Epub 2017 Jun 23.

Section of Clinical Medicine and Ageing, Department of Clinical and Experimental Medicine, University of Surrey, Guildford GU2 7PX, UK.

Aim: To examine whether diabetes and the degree of glycaemic control is associated with an increased risk of acute eye infection, and prescribing of ocular antimicrobial agents.

Design And Setting: A retrospective cohort study was carried out using the Royal College of General Practitioners Research and Surveillance Centre database (RCGP RSC), a large primary care database in the United Kingdom. We compared ocular infection rates in people aged ≥15 years without diabetes to those with diabetes, both type 1 and type 2. Read More

J Parasit Dis 2017 Jun 22;41(2):367-370. Epub 2016 Jun 22.

College of Veterinary Sciences and Animal Husbandry, UP Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura, 281001 India.

Two adult Barbari goats were presented to the Division of Animal Health of the Institute with the history of unilateral protrusion of the left eye ball, blepharitis and congestion of the conjunctival membrane. Physical and ultrasonographical examination revealed large fluctuating fluid filled bladder with distinct dimensions. The cysts were successfully removed along with its membrane and parasitological examination revealed it as a , the intermediate stage of . Read More

Arch Soc Esp Oftalmol 2017 Sep 25;92(9):412-418. Epub 2017 May 25.

Programa de Biología Celular y Molecular, Facultad de Medicina-ICBM, Universidad de Chile, Santiago, Chile.

Objective: To determine prevalence of Demodex spp. and infestation index (II) by the parasite among patients of different ages with blepharitis and to assess association with occurrence of cylindrical dandruff (CC).

Materials And Methods: Prospective study including patients diagnosed with posterior blepharitis between 2013 and 2015, without previous acaricide treatment, was conducted by Fundación Oftalmológica Los Andes (Chile). Read More

Int J Ophthalmol 2017 18;10(5):776-781. Epub 2017 May 18.

School of medicine, College of Medicine and Health Sciences, Hawassa University, Hawassa P.O.box 1560, Ethiopia.

Aim: To assess the pattern of ocular manifestation and associated factors among human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients on highly active antiretroviral therapy (HAART) at Hawassa University Referral Hospital, Southern Ethiopia.

Methods: A cross sectional study was conducted from January 2014 to April 2015. After obtaining informed written consent, 240 adult HIV/AIDS patients on HAART were randomly selected regardless of their ophthalmic symptoms, WHO status or CD4 count. Read More

Epidemiol Infect 2017 09 19;145(12):2520-2529. Epub 2017 May 19.

Anova Health Institute,Johannesburg,South Africa.

Introduction of antiretroviral therapy (ART) has dramatically reduced the incidence of infectious ocular diseases in human immunodeficiency virus (HIV)-infected individuals. However, the effects of long-term ART and chronic HIV infection on the eye are ill-defined. This study determined the occurrence and severity of ocular diseases among 342 participants in a rural South African setting: HIV-naïve (n = 105), HIV-infected ART-naïve (n = 16), HIV-infected on ART for 36 months (long-term ART; n = 165). Read More