176,080 results match your criteria Bladder Management
BJU Int 2018 Dec 11. Epub 2018 Dec 11.
Department of Urology, Antwerp University Hospital, Edegem, Belgium.
Objectives: To assess clinical follow-up data over 24 months using the standardized tined lead implantation technique, comparing the use of the curved vs straight stylet.
Patients And Methods: Single tertiary center, prospective study (August 2013 - June 2015) involving 40 patients with overactive bladder and 15 with non-obstructive urinary retention refractory to first-line treatment.
Primary Outcome: successful tined lead procedure; intention to treat analysis at 12 and 24 months. Read More
J Cell Biochem 2018 Dec 9. Epub 2018 Dec 9.
Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
FAM83H-AS1, also known as oncogenic long noncoding RNA (lncRNA)-3, is a novel lncRNA that has been suggested to be dysregulated in a variety of human cancers. However, the expression status and function of FAM83H-AS1 in bladder cancer are still unknown. The object of our study is to explore the clinical value of FAM83H-AS1 in patients with bladder cancer and the biological function of FAM83H-AS1 in bladder cancer cells. Read More
J Physiol 2018 Dec 7. Epub 2018 Dec 7.
Department of Pharmacology, University of Vermont, Burlington, VT, 05405.
Key Points Summary: K 7 channels are a family of voltage-dependent K channels expressed in many cell types, which open in response to membrane depolarization to regulate cell excitability. Drugs that target K 7 channels are used clinically to treat epilepsy. Interestingly, these drugs also cause urinary retention, but it was unclear how. Read More
J Appl Clin Med Phys 2018 Dec 7. Epub 2018 Dec 7.
Department of Oncology Physics, Edinburgh Cancer Centre, Western General Hospital, Edinburgh, UK.
Background: Independent verification of the dose delivered by complex radiotherapy can be performed by electronic portal imaging device (EPID) dosimetry. This paper presents 5-yr EPID in vivo dosimetry (IVD) data obtained using the Dosimetry Check (DC) software on a large cohort including breast, lung, prostate, and head and neck (H&N) cancer patients.
Material And Methods: The difference between in vivo dose measurements obtained by DC and point doses calculated by the Eclipse treatment planning system was obtained on 3795 radiotherapy patients treated with volumetric modulated arc therapy (VMAT) (n = 842) and three-dimensional conformal radiotherapy (3DCRT) (n = 2953) at 6, 10, and 15 MV. Read More
Med Phys 2018 Dec 11. Epub 2018 Dec 11.
Department of Radiation Oncology, Stanford University, 875 Blake Wilbur Drive, Stanford, CA, 94305-5847, USA.
Purpose: Few features characterizing the dosimetric properties of the patients are included in currently available dose-volume histogram (DVH) prediction models, making it intractable to build a correlative relationship between the input and output parameters. Here we use PTV-only treatment plans of the patients (i.e. Read More
Eur J Nucl Med Mol Imaging 2018 Dec 11. Epub 2018 Dec 11.
Departments of Radiology and Medical Physics, University of Wisconsin - Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
Genes Genomics 2018 Dec 8. Epub 2018 Dec 8.
Department of Informatics, University of Evora, 7004-516, Evora, Portugal.
Background: Identification of differentially expressed genes, i.e., genes whose transcript abundance level differs across different biological or physiological conditions, was indeed a challenging task. Read More
Int Urogynecol J 2018 Dec 7. Epub 2018 Dec 7.
James Cook University Hospital, Middlesbrough, TS4 3BW, UK.
Introduction And Hypothesis: Sexual function is being increasingly recognized as an important patient-reported outcome. Sacral neuromodulation (SNM) is a treatment with an expanding list of indications. The effect of sacral neuromodulation on sexual function has been examined in a number of studies with variable results. Read More
World J Urol 2018 Dec 10. Epub 2018 Dec 10.
Department of Urology, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, Korea.
Purpose: To develop and validate novel nomograms to predict recurrence and progression after transurethral resection of bladder tumor (TURBT) in Korean patients with non-muscle-invasive bladder cancer (NMIBC).
Methods: We retrospectively analyzed the clinical data on 970 newly diagnosed NMIBC patients after TURBT between 2000 and 2013 in a single institution. We used multivariate Cox proportional hazard models to identify the significant predictors of recurrence and progression, which resulted in the construction of the nomograms predicting the 5-year probability of recurrence and progression. Read More
World J Urol 2018 Dec 10. Epub 2018 Dec 10.
Sino-Singapore Eco-city Hospital of Tianjin Medical University, No. 3333, Hechang Road, Binhai New Area, Tianjin City, 300467, China.
Background: Bladder cancer is the most common malignancy of urinary system with high morbidity and mortality. In general, the development and progression of bladder cancer are complicated pathological processes, and the treatment methods mainly include surgical resection, radiotherapy, chemotherapy, and combined therapy. In recent years, targeted therapy has made progress in the treatment of bladder cancer. Read More
World J Urol 2018 Dec 7. Epub 2018 Dec 7.
H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Introduction: Intravesical therapy has been an important aspect of the management of non-muscle invasive bladder cancer (NMIBC) for 40 years. Bacillus Calmette-Guerin (BCG) is considered standard of care for intermediate and high-grade non-invasive disease, yet understanding the nuances of subsequent intravesical therapy is important for any provider managing bladder cancer. Herein, we review the literature and describe optimal use of intravesical therapies for NMIBC. Read More
Rom J Morphol Embryol 2018 ;59(3):773-780
Department of Nephrology and Dialysis, "St. John" Emergency Clinical Hospital, Clinical Department No. 3, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania;
The aim of the study was to observe similarities and differences regarding surgical safety and prognosis between en bloc bipolar resection and monopolar transurethral resection of bladder tumors (TURBTs) in medium size papillary non-muscle invasive bladder tumors (NMIBTs). A total of 90 patients with papillary bladder tumors presenting a diameter between 1 and 3 cm were equally divided and alternatively assigned for en bloc bipolar ablation (the study group) and conventional TURBT (the control group). During one year, every three months, the follow-up was performed and the protocol included urinary cytology and cystoscopy. Read More
Rom J Morphol Embryol 2018 ;59(3):755-762
Department of Research Methodology, University of Medicine and Pharmacy of Craiova, Romania;
Multiple sclerosis (MS) is a complex chronic neurodegenerative disease that involves an abnormal autoimmune response directed against the brain, nerves and spinal cord; it is considered the most frequent cause of neurological disability, because MS-associated inflammatory lesions can affect a wide range of systems to a varying degree and may cause a plethora of neurological comorbidities and symptoms. The symptoms are quite variable from patient to patient and depend on the spatial distribution of the central nervous system (CNS) lesions, but usually involve sensory disturbances, cognitive deficits, unilateral vision loss, bladder dysfunction, ataxia, fatigue, double vision, weakness of the limbs and intestinal disorders. Experimental autoimmune encephalitis (EAE) mouse model reproduces the pathological features of the human disease, and is a widely used model used for studying the pathology and different treatment options in the preclinical stage. Read More
Case Rep Hematol 2018 11;2018:9750532. Epub 2018 Nov 11.
Physician, General Medicine, Hospital de Carabineros de Chile, Simón Bolívar 2200, Ñuñoa 7770199, Santiago, Chile.
Myelodysplasia is a clonal disorder characterized by progressive cytopenias. Intravescial BCG is standard immunotherapy for superficial bladder cancer. We present a patient with transfusion-dependent myelodysplasia whose blood counts normalized during treatment with intravesical BCG for bladder cancer. Read More
Arab J Urol 2018 Dec 18;16(4):441-445. Epub 2018 May 18.
Department of Urology, Hisar Intercontinental Hospital, Istanbul, Turkey.
Objective: To evaluate the effectiveness and safety of bilateral same-session flexible ureterorenoscopy (f-URS) in the treatment of bilateral renal and/or ureteric stone disease.
Patients And Methods: From October 2007 to December 2015, 62 patients who had undergone bilateral, same-session f-URS were included in the study. The procedures were performed under general anaesthesia, in lithotomy, and initiated on the side in which the patient was clinically symptomatic or on the side in which the stone was smaller. Read More
Arab J Urol 2018 Dec 26;16(4):422-428. Epub 2018 Jul 26.
Department of Urology, Benha Faculty of Medicine, Benha University, Benha, Egypt.
Objective: To evaluate the efficacy of silodosin therapy, as a new α-adrenergic receptor (α-AR) blocker, on the success rate of semi-rigid ureteroscopy (URS) for the management of large distal ureteric stones.
Patients And Methods: This prospective study recruited 127 adult patients with single distal ureteric stone of ≥1 cm. The patients were randomly allocated to two groups: the first group included 62 patients who received silodosin (8 mg) for 10 days before URS (Silodosin group), whilst the second group included 65 patients who received placebo, in the form of multivitamins, for 10 days before URS (Placebo group). Read More
Arab J Urol 2018 Dec 11;16(4):417-421. Epub 2018 Jun 11.
M.S. Ramaiah Hospital, Bangalore, India.
Objective: To describe the effectiveness and safety of our novel technique of simultaneous percutaneous cystolithotripsy with transurethral resection of prostate (TURP) for patients with benign prostatic hyperplasia (BPH) complicated with large vesical calculi.
Patients And Methods: This was a retrospective analysis of 25 patients who underwent simultaneous percutaneous cystolithotripsy with TURP between January 2012 and January 2016. Technique: A 28-F Amplatz sheath was inserted percutaneously into the bladder after sequential dilatation under cystoscopic guidance. Read More
Arab J Urol 2018 Dec 5;16(4):411-416. Epub 2018 Jul 5.
Department of Urology and Men's Health, Al Garhoud Private Hospital, Dubai, United Arab Emirates.
Objectives: To report our experience with the emerging technique of thulium laser enucleation of the prostate (ThuLEP) for the treatment for prostate hyperplasia.
Patients And Methods: Our inclusion criteria were an International Prostate Symptom Score (IPSS) of >15 and a quality-of-life (QoL) score of >3 in patients with confirmed bladder outflow obstruction, no longer responsive to medical therapy, with a significant post-void residual urine volume (PVR; >100 mL), with or without recurrent urinary tract infection and/or acute urinary retention. Patients with neurogenic bladder, urethral strictures, bladder stones, and previously failed transurethral prostate surgery were excluded. Read More
Arab J Urol 2018 Dec 7;16(4):391-396. Epub 2018 Aug 7.
Department of Neurosurgery, Al-Mustansiriya University, Baghdad, Iraq.
Objectives: To present our experience, in Iraq, with sacral neuromodulation (SNM) in patients with refractory lower urinary tract dysfunction, with discussion of the factors that affect the response rate.
Patients And Methods: In this prospective, clinical, interventional study, 24 patients were evaluated and treated by a team comprised of a Urologist and a Neurosurgeon with SNM over a 1.5-year period. Read More
Arab J Urol 2018 Dec 14;16(4):386-390. Epub 2018 Jul 14.
Department of Urology, Christian Medical College and Hospital, Vellore, Tamilnadu, India.
Objective: To identify primary tumour-related factors at transurethral resection of bladder tumour (TURBT) that may predict positive distal ureteric margins (PUM) at the time of radical cystectomy (RC).
Patients And Methods: A retrospective, cohort study was conducted using our institution's data from June 2007 to June 2016. Patients who underwent TURBT followed by RC for non-metastatic urothelial carcinoma (UC) of the bladder were identified. Read More
Nurs Open 2019 Jan 14;6(1):109-115. Epub 2018 Sep 14.
School of Nursing and Midwifery Dezful University of Medical Sciences Dezful Iran.
Aim: The present study aimed to determine the level of applying safety standards in treatment and therapy processes.
Design: In the present descriptive study, 120 cases of nasogastric intubation, bladder catheterization and intramuscular and intravenous injections done by emergency staff were randomly selected.
Methods: The data were collected by a two-section checklist including demographic features and four sheets of observation. Read More
Rep Pract Oncol Radiother 2018 Nov-Dec;23(6):510-516. Epub 2018 Oct 19.
Department of Radiation Oncology, Hospital de Navarra, Pamplona, Spain.
Purpose: To evaluate dosimetric and clinical findings of MRI-guided HDR brachytherapy (HDR-B) for cervical carcinoma.
Material And Methods: All patients had a CT, MRI and pelvic-paraaortic lymphadenectomy. Treatment: pelvic (+/-)para-aortic3D/IMRT radiotherapy (45 Gy), weekly cisplatin and HDR-B and pelvic node/parametrial boost 60 Gy until interstitial brachytherapy was done. Read More
Turk J Emerg Med 2018 Dec 23;18(4):170-171. Epub 2018 Feb 23.
TOBB Economy and Technology University, Faculty of Medicine, Department of Urology, Yaşam Caddesi No: 5 Söğütözü, 06510, Ankara, Turkey.
Urinary retention is defined as the inability to void; frequently the patient is able to void partially, thus can not completely empty the bladder and diagnosed by increased post-void residual urine (PVR) volumes. It is usually seen in men, but a rare condition in women. The etiological factors may be neurological, anatomical, infectious or pharmacological. Read More
Bladder Cancer 2018 3;4(Suppl 1):S14-S15. Epub 2018 Oct 3.
Division of Urology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.
Res Rep Urol 2018 16;10:219-225. Epub 2018 Nov 16.
Department of Surgery, Division of Urology, Duke University Medical Center, Durham, NC, USA,
Purpose: Diabetes is a grave and progressive condition characterized by debilitating complications. Diabetic bladder dysfunction (DBD) is a very common complication with no specific treatments currently available. Unlike other tissues affected by this disease, the bladder is subjected to two independent insults; 1) polyuria, created by the osmotic effects of glucose in the urine, and 2) hyperglycemia itself. Read More
PeerJ 2018 4;6:e6036. Epub 2018 Dec 4.
Central Laboratory, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, Haikou, China.
Background: Bladder cancer is a malignant tumor in the urinary system with high mortality and recurrence rates. However, the causes and recurrence mechanism of bladder cancer are not fully understood. In this study, we used integrated bioinformatics to screen for key genes associated with the development of bladder cancer and reveal their potential molecular mechanisms. Read More
Pain 2018 Dec 5. Epub 2018 Dec 5.
Visceral Pain Research Group, Centre for Neuroscience, College of Medicine and Public Health, Flinders University, Bedford Park, South Australia, 5042, AUSTRALIA.
Primary afferent neurons transduce distension of the bladder wall into action potentials that are relayed into the spinal cord and brain, where autonomic reflexes necessary for maintaining continence are coordinated with pathways involved in sensation. However, the relationship between spinal circuits involved with physiological and nociceptive signalling from the bladder have only been partially characterised. We used ex-vivo bladder afferent recordings to characterise mechanosensitive afferent responses to graded distension (0-60mmHg) and retrograde tracing from the bladder wall to identify central axon projections within the dorsal horn of the lumbosacral spinal cord. Read More
Biomed Res 2018 ;39(6):269-277
Department of Biochemistry, Graduate School of Medicine, University of the Ryukyus.
Pelvic venous congestion (PC) is thought to be related to several diseases of the lower urinary tract (LUT). We examined the characteristics of the LUT in rats with PC. To create PC, female rats were anesthetized with isoflurane, and the bilateral common iliac veins and bilateral uterine veins were ligated. Read More
Neural Regen Res 2019 Jan;14(1):149-155
Department of Neurosurgery, PLA General Hospital, Beijing, China.
Tethered cord syndrome is a progressive disease with a typically insidious onset in infants and children, and which can lead to persistent progress of neurological deficits and a high rate of disability without timely intervention. The purpose of this study was to investigate the curative effect of microsurgery in children with different types of tethered cord syndrome. In this study, we analyzed 326 patients with tethered cord syndrome, aged from 2 months to 14 years old, who were followed for 3-36 months after microscopic surgery. Read More
Neural Regen Res 2019 Feb;14(2):222-226
Department of Neural & Behavioral Sciences, Penn State University College of Medicine, Hershey, PA, USA.
The devastating losses following traumatic spinal cord injury (SCI) encompass the motor, sensory and autonomic nervous systems. Neurogenic bowel is a slow transit colonic dysfunction marked by constipation, rectal evacuation difficulties, decreased anorectal sensation, fecal incontinence or some combination thereof. Furthermore, neurogenic bowel is one of the most prevalent comorbidities of SCI and is recognized by afflicted individuals and caregivers as a lifelong physical and psychological challenge that profoundly affects quality of life. Read More
Z Naturforsch C 2018 Dec 8. Epub 2018 Dec 8.
Department of Catering and Tourism, University of Food Technologies, Plovdiv, Bulgaria.
The study's objective was to investigate the volatile compounds, assess the total phenolic content and phenolic acids profile, determine the antioxidant capacity and evaluate the anthocyanin and flavonoid contents in stinging nettle (Urtica dioica L.), tansy (Tanacetum vulgare L.), bladder campion (Silene vulgaris (Moench) Garcke) and rosehip fruit (Rosa canina L. Read More
J Exp Biol 2018 Dec 10. Epub 2018 Dec 10.
Bamfield Marine Sciences Centre, 100 Pachena Road, Bamfield, BC, V0R 1B0, Canada.
Ureotelic elasmobranchs require nitrogen for both protein growth and urea-based osmoregulation, and therefore are probably nitrogen-limited in nature. Mechanisms exist for retaining and/or scavenging nitrogen at gills, kidney, rectal gland, and gut, but as yet, the latter are not well characterized. Intestinal sac preparations of the Pacific spiny dogfish shark () incubated strongly reabsorbed urea from the lumen after feeding, but mucosal fluid ammonia concentrations increased with incubation time. Read More
BMJ Open 2018 Dec 9;8(12):e023136. Epub 2018 Dec 9.
Department of Urology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Objective: Ileal conduit urinary diversion (ICUD) is the most common procedure after radical cystectomy. Although complications have been reported, few patients with ICUD and bladder preservation controls have been available for long-term follow-up. This study compared the long-term effect of structural changes after cystectomy with ICUD to that in bladder preservation controls. Read More
Clin Biochem 2018 Dec 4. Epub 2018 Dec 4.
Department of Urology, University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany; National Center for Tumor Diseases (NCT), Partner site Dresden, Dresden, Germany. Electronic address:
Background: Cell-free DNA (cfDNA) is proposed to be a valuable source of biomarkers in liquid biopsies for various diseases as it is supposed to partially originate from tumor cells. However, data about the diagnostic implications of cfDNA in urine for the detection of bladder cancer (BCa) is sparse.
Methods: We evaluated the usability of urinary cfDNA for diagnostic purposes compared to urine sediment DNA (sDNA) in 53 BCa patients and 36 control subjects by analyzing two abundant point-mutations (C228T/C250T) in the TERT promoter using Next-Generation Sequencing. Read More
Urol Oncol 2018 Dec 8. Epub 2018 Dec 8.
Vancouver Prostate Centre, University of British Columbia, Vancouver, Canada. Electronic address:
Background: Despite years of slow progress, muscle invasive bladder cancer (MIBC) is finally entering the era of molecularly guided targeted therapy. However, tumor heterogeneity is high in MIBC and may impact treatment response and resistance. The objective of this review is to dissect recent insights into inter- and intratumor heterogeneity (ITH) in MIBC, with emphasis on the clinical implications of this heterogeneity for biomarker-driven strategies and the development of new therapies. Read More
Cancer Epidemiol 2018 Dec 5;58:83-88. Epub 2018 Dec 5.
Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada; Division of Urology, University of Montreal Hospital Center (CHUM), Montreal, Quebec, Canada.
Background: Patients with organ confined muscle-invasive bladder cancer (MIBC) who are candidates for radical cystectomy (RC) should receive neoadjuvant chemotherapy (CHT). However, the most contemporary CHT use rates indicate low adherence to these guidelines. We tested contemporary neoadjuvant CHT rates and associated cancer-specific mortality (CSM) and overall mortality (OM) in pT2N0 MIBC patients treated with RC. Read More
Eur J Cancer 2018 Dec 5;106:234-243. Epub 2018 Dec 5.
Institute of Pathology, Technical University Munich, Munich, Germany. Electronic address:
Background: Recently, the Food and Drug Administration (FDA)/European Medicines Agency (EMA) restricted first-line use of atezolizumab and pembrolizumab in patients with metastasised urothelial carcinoma by defining distinct programmed cell death ligand-1 cut-offs. We analysed the diagnostic performance of all FDA/EMA-approved programmed cell death ligand-1 assays with emphasis on new restrictions for first-line treatment with atezolizumab and pembrolizumab.
Patients And Methods: Two hundred fifty-one urothelial carcinomas were analysed on tissue microarrays with four cores of each tumour. Read More
Urology 2018 Dec 4. Epub 2018 Dec 4.
Vanderbilt University Medical Center, Department of Urologic Surgery, Nashville, TN, USA. Electronic address:
Objectives: To estimate effective dose of kidney-ureter-bladder (KUB) radiographs in a contemporary population of patients with urolithiasis.
Methods: A retrospective review was performed to identify patients visiting a urology clinic for urolithiasis where a KUB was obtained and whom had a recent CT. Effective dose for KUBs was estimated using a Monte Carlo based simulation program and for CT utilizing the reported dose-length-product. Read More
Urology 2018 Dec 4. Epub 2018 Dec 4.
Department of Urology, Hitit University School of Medicine, Corum, Turkey.
Objective: To evaluate ultrasonically determined bladder wall thickness (BWT) and prostatic calcification presence, in men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), and to correlate the findings with patient characteristics and the UPOINT classification system.
Material And Methods: Between January 2008 and December 2017 data of 1294 patients diagnosed with chronic prostatitis, in a single urology clinic, meeting a number of selective inclusion/exclusion criterias, were retrospectively analyzed. Patients, compliant to fill out all requested questionnaires, between the ages of 21-65 years were included to the study. Read More
Urol Oncol 2018 Dec 6. Epub 2018 Dec 6.
Institute for Technology Assessment, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA. Electronic address:
Purpose: Our purpose was to evaluate the effect of PD-L1 testing on the cost-effectiveness of pembrolizumab for second-line treatment of advanced urothelial carcinoma in the bladder from the U.S. societal perspective. Read More
Int J Radiat Oncol Biol Phys 2018 Dec 6. Epub 2018 Dec 6.
The Institute of Cancer Research, London, United Kingdom.
Purpose: To establish the toxicity profile of high-dose pelvic lymph node intensity-modulated radiation therapy (IMRT) and to assess whether it is safely deliverable at multiple centers.
Methods And Materials: In this phase 2 noncomparative multicenter trial, 124 patients with locally advanced, high-risk prostate cancer were randomized between prostate-only IMRT (PO) (74 Gy/37 fractions) and prostate and pelvic lymph node IMRT (P&P; 74 Gy/37 fractions to prostate, 60 Gy/37 fractions to pelvis). The primary endpoint was acute lower gastrointestinal (GI) Radiation Therapy Oncology Group (RTOG) toxicity at week 18, aiming to exclude a grade 2 or greater (G2+) toxicity-free rate of 80% in the P&P group. Read More
J Pediatr Urol 2018 Nov 14. Epub 2018 Nov 14.
Department of Woman, Child and of General and Specialized Surgery, Università Della Campania "Luigi Vanvitelli", Via Luigi De Crecchio 2, 80138, Napoli, Italy.
Introduction: The nocturnal polyuria is considered a significant predictive value for response to desmopressin. The cutoff value useful to define nocturnal polyuria is still a matter of debate. Moreover, it is current notion that maximal voided volume (MVV) could be used as a predictor for desmopressin response. Read More
Adv Biol Regul 2018 Nov 22. Epub 2018 Nov 22.
Section Molecular Immunology, Institute of Immunology, Heidelberg University Hospital, Heidelberg, Germany. Electronic address:
Sulforaphane (SFN) is a naturally occurring isothiocyanate derived from cruciferous vegetables such as broccoli. It has been reported to inhibit the growth of a variety of cancers, such as breast, prostate, colon, skin, lung, gastric or bladder cancer. SFN is supposed to act primarily as an antioxidant due to the activation of the Nrf2-Keap1 signaling pathway. Read More
J Perianesth Nurs 2018 Dec 5. Epub 2018 Dec 5.
Purpose: Postoperative ureteroscopy patients can develop bladder spasms, complaints of pain, and the urgent need to void during emergence from anesthesia. Discomfort leads to patient agitation, resulting in a risk to patient safety. The purpose of this study was to determine the effectiveness of a preemptive preoperative belladonna and opium (B + O) suppository on postoperative bladder comfort, narcotic requirements, and length of stay of ureteroscopy patients. Read More
Biochem Biophys Res Commun 2018 Dec 6. Epub 2018 Dec 6.
Department of Urology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou City, Fujian Province, 362000, China. Electronic address:
Accumulating evidence has shown the critical role of long non-coding RNAs (lncRNAs) during cancer progression. However, the involvement of ELF3-AS1 in bladder cancer (BC) remains largely unclear. By lncRNA profiling, we identified ELF3-AS1 as a novel oncogenic lncRNA during bladder cancer development. Read More
J Pediatr Surg 2018 Nov 7. Epub 2018 Nov 7.
Department of Paediatric Urology, Birmingham Children's Hospital, UK. Electronic address:
Aim: Posterior urethral valves (PUVs) are the most common cause of congenital bladder outlet obstruction (BOO) in boys and end-stage renal failure (ESRF) in childhood. In the 1980s, 1 in 4000 boys had PUV. Presentation was 1/3 antenatal/neonatally, 1/3 postnatal, 1/3 late (>1 year). Read More
J Pediatr Surg 2018 Nov 6. Epub 2018 Nov 6.
Department of Paediatric Urology, Birmingham Children's Hospital, UK. Electronic address:
Aim: The most common cause of congenital bladder outlet obstruction (BOO) is posterior urethral valves (PUV). Initial treatment requires decompression, but transurethral incision (TUI) or primary diversion is all described. There is no randomized control trial to guide management. Read More
Med Dosim 2018 Dec 5. Epub 2018 Dec 5.
The University of Hong Kong, Department of Clinical Oncology, Pok Fu Lam, Hong Kong.
The purpose of this study is to develop and evaluate a statistics-based model to predict the achievability of the planning criteria for intensity-modulated radiation therapy planning. A statistics-based model was proposed to predict the achievability of the planning criteria based on the structure set. A retrospective study was performed to validate the proposed model. Read More
Eur Urol 2018 Dec 5. Epub 2018 Dec 5.
Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Guangzhou Institute of Biomedicine and Health, Chinese Academy of Science, Guangzhou, People's Republic of China; CNRS Emeritus CNRS UMR 7057 Matter and Complex Systems, University Paris Denis Diderot, Paris, France; INSERM UMR 1186, Integrative Tumor Immunology and Genetic Oncology, Gustave Roussy, Université Paris-Saclay, Villejuif, France. Electronic address:
J Pediatr Surg 2018 Nov 7. Epub 2018 Nov 7.
Department of Paediatric Urology, Great Ormond Street Hospital for Children, Great Ormond Street, London, UK. Electronic address:
This is based on the 2018 Storz Urology Lecture at the BAPS Conference and is a personal review of three reconstructive paediatric urological conditions: hypospadias, congenital adrenal hyperplasia, and bladder exstrophy from the perspective of changing expectations and outcomes. LEVEL OF EVIDENCE: V (Expert Opinion). Read More