21,480 results match your criteria Bladder Management

Rethinking the approach to evaluation and management of overactive bladder.

Patrick J Shenot

Can J Urol 2021 Jun;28(3):10705

Department of Urology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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The Genitourinary Pathology Society Update on Classification of Variant Histologies, T1 Substaging, Molecular Taxonomy, and Immunotherapy and PD-L1 Testing Implications of Urothelial Cancers.

Adv Anat Pathol 2021 Jul;28(4):196-208

Department of Pathology, West German Cancer Center/University Hospital Essen, University of Duisburg-Essen, Duisburg.

The Genitourinary Pathology Society (GUPS) undertook a critical review of the recent advances in bladder cancer focusing on important topics of high interest for the practicing surgical pathologist and urologist. This review represents the second of 2 manuscripts ensuing from this effort. Herein, we address the effective reporting of bladder cancer, focusing particularly on newly published data since the last 2016 World Health Organization (WHO) classification. Read More

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Accuracy of Frozen Section Analysis of Urethral and Ureteral Margins During Radical Cystectomy for Bladder Cancer: A Systematic Review and Diagnostic Meta-Analysis.

Eur Urol Focus 2021 Jun 11. Epub 2021 Jun 11.

Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

Context: The question of the ability of frozen section analysis (FSA) to accurately detect malignant pathology intraoperatively has been discussed for many decades.

Objective: We aimed to conduct a systematic review and meta-analysis assessing the diagnostic estimates of FSA of the urethral and ureteral margins in patients treated with radical cystectomy (RC) for bladder cancer (BCa).

Evidence Acquisition: The MEDLINE and EMBASE databases were searched in February 2021 for studies analyzing the association between FSA and the final urethral and ureteral margin status in patients treated with RC for BCa. Read More

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Outcome Prediction for Patients With Ischemic Stroke in Acute Care: New Three-Level Model by Eating and Bladder Functions.

Ann Rehabil Med 2021 Jun 14. Epub 2021 Jun 14.

Department of Rehabilitation Medicine, Nishinomiya Kyoritsu Neurosurgical Hospital, Nishinomiya, Japan.

Objective: To develop a new prediction model by combining independence in eating and bladder management functions, and to assess its utility in an acute care setting.

Methods: Patients with ischemic stroke who were admitted in our acute stroke care unit (n=250) were enrolled in this study. Functional Independence Measure (FIM) scores for eating and bladder management on the initial day of rehabilitative treatment (median, 3 days) were collected as predictive variables. Read More

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The prevalence of right-sided colonic diverticulosis in a New Zealand population.

ANZ J Surg 2021 Jun 14. Epub 2021 Jun 14.

Department of General Surgery, Christchurch Hospital, Christchurch, New Zealand.

Background: Once considered to be a congenital condition, the epidemiology of right-sided colonic diverticulosis (RCD) is evolving. Acute diverticulitis (AD) is a complication of RCD which is frequently misdiagnosed as appendicitis, resulting in unnecessary surgery, as there is strong evidence supporting medical management for right-sided AD. In general, the incidence of AD correlates with the prevalence of RCD, which shows marked geographic variation. Read More

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CRISPReader System Sensing the Ets-1 Transcription Factor Can Effectively Identify Cancer Cells.

Front Mol Biosci 2021 28;8:672040. Epub 2021 May 28.

HuiZhou Municipal Central Hospital, Huizhou, China.

By targeting key genes, the CRISPR system can effectively exert its anti-cancer activity. The latest research suggests that the CRISPReader system that regulates gene transcription can effectively target and inhibit bladder cancer cells by sensing transcription factors such as c-Myc and Get-1 in the cell. An interesting question is whether the CRISPReader system can exert its anti-cancer ability against a variety of tumors by sensing the broad-spectrum transcription factor Ets-1. Read More

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Pooled Analysis on the Effectiveness and Safety of Lipegfilgrastim in Patients With Urological Malignancies in the Real-World Setting.

Front Oncol 2021 28;11:655355. Epub 2021 May 28.

Department of Internal Medicine I, University Hospital St. Poelten, Karl Landsteiner, University of Health Sciences, St. Poelten, Austria.

Lipegfilgrastim is a long-acting glycopegylated granulocyte-colony stimulating factor (G-CSF) approved for the management of chemotherapy-induced neutropenia. In general, there is little information on the use of any G-CSFs specifically in patients with urological malignancies receiving chemotherapy. This report combines information from two prospective non-interventional studies on the prophylactic use of lipegfilgrastim in urological cancer patients receiving chemotherapy in the real-world setting. Read More

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Neonatal Renal Failure in the Setting of Anorectal Malformation: A Case Report and Literature Review.

Cureus 2021 May 12;13(5):e14984. Epub 2021 May 12.

Pediatric Surgery, University of Missouri Kansas City School of Medicine, Kansas City, USA.

Anorectal malformations (ARMs) can occur in isolation or in association with other anomalies, most commonly those of the genitourinary systems. Morbidity and mortality are highest among patients who develop end-stage renal disease (ESRD) either from severe congenital anomalies (dysplastic kidneys) or from repeated infections in those who have vesicoureteral reflux or persistent recto-urinary fistulas. We describe our management strategy for a patient born with an ARM and bilateral dysplastic kidneys to highlight the nuances and complex decision-making considerations required in taking care of this complex patient population. Read More

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Successful conservative management of a spontaneous intraperitoneal urinary bladder rupture secondary to benign prostatic hyperplasia: a case report.

Pan Afr Med J 2021 16;38:268. Epub 2021 Mar 16.

Department of Urology A, Ibn Sina University Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.

A spontaneous intraperitoneal bladder rupture is a rare, serious and life-threatening surgical emergency of various etiologies, with unspecific clinical presentation, and difficult diagnosis. Surgical treatment is the standard therapy for intraperitoneal bladder rupture; however, there is an increasing tendency toward conservative management in selected patients with favorable characteristics. Herein, we report a rare case of a 65-year-old male patient presented to the emergency department with intraperitoneal bladder rupture following an episode of acute urinary retention due to benign prostatic hyperplasia, and which was successfully managed conservatively with urinary bladder catheterization and antibiotic therapy, without any complication. Read More

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Clinico-epidemiological profile and outcomes of babies with neural tube defects in a tertiary care center in Northern India.

J Matern Fetal Neonatal Med 2021 Jun 13:1-6. Epub 2021 Jun 13.

Department of Neonatology, Dr Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, New Delhi, India, Atal Bihari Vajpayi Institute of Medical Sciences (ABVIMS) and Dr Ram Manohar Lohia Hospital, New Delhi, India.

Introduction: Neural tube defects constitute a major source of disability among children. Proper management requires accurate diagnosis, an assessment of the severity of the lesion, a decision whether intervention is warranted, the nature of the intervention, and educating the family of the need for lifelong medical care. But to do so, reliable data regarding presentation and outcome is very crucial. Read More

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J Endourol 2021 Jun 13. Epub 2021 Jun 13.

CHU Tours, Department of urology, Tours, France.

Purpose: The bladder cuff management and its surgical approach represent an essential and debated step in radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC). The objective of our study was to determine which bladder-cuff management has the best oncological outcomes in terms of bladder recurrence-free survival ( BRFS).

Methods: We retrospectively analyzed all patients who underwent an open robot-assisted laparoscopic (RNU) or a combined RNU between March 2012 and March 2019 in three academic hospitals. Read More

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Endoscopic treatment of primary vesicoureteral reflux in children with two different bulking agents, high success and low complication rates: comparison of Dexell and Vantris.

Actas Urol Esp 2021 Jun 10. Epub 2021 Jun 10.

Departamento de Cirugía Pediátrica, Facultad de Medicina, Universidad Sütçü İmam, Kahramanmaraş, Turquía.

Introduction And Objectives: To compare the results in terms of efficacy and safety of the endoscopic management for vesicoureteral reflux (VUR) in two different standardized primary VUR cohorts treated with Dexell and Vantris.

Patients: 128 refluxing renal units (RRU) in 87 patients with primary VUR (64 females, 23 males). Patients with secondary VUR and severe bladder and bowel dysfunction were excluded. Read More

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Current status of intravesical therapies for bladder pain syndrome (BPS): a narrative review of emerging evidence.

Urology 2021 Jun 9. Epub 2021 Jun 9.

Chief of Department, Consultant Urological Surgeon, Professor of Urology, President of Scandinavian Association of Urology; Department of Clinical Medicine, University of Bergen, Bergen, Norway; Department of Urology, Haukeland University Hospital, Bergen, Norway.

Bladder pain syndrome (BPS) is a complex condition, which can have debilitating sequelae for patients. Many elements of BPS remain poorly understood including pathophysiology, diagnosis and treatment. Navigating patient care can therefore be challenging for the clinician. Read More

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Impact of sex on response to BCG in non-muscle invasive bladder cancer patients: a contemporary review from a tertiary care center.

World J Urol 2021 Jun 12. Epub 2021 Jun 12.

Department of Urology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Purpose: Female sex has been implicated with higher stage at diagnosis and as a negative prognostic factor amongst patients with non-muscle invasive bladder cancer (NMIBC). Whether this holds true with contemporary management paradigms is unknown. We analyzed a cohort of patients treated with adequate bacillus Calmette-Guerin (BCG) for NMIBC in an effort to identify sex-specific influence on BCG response. Read More

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How I Handle Retreatment of LUTS Following a Failed MIST.

Curr Urol Rep 2021 Jun 11;22(8):40. Epub 2021 Jun 11.

Department of Urology, Weill Cornell Medical College of Cornell University, 425 East 61st street, 12th floor, New York, NY, 10065, USA.

Purpose Of Review: The goal of this paper is to review retreatment management after failed minimally invasive treatment (MIST) of various technologies.

Recent Findings: A failed MIST can be defined by the return, persistence, or worsening of LUTS, as documented by symptom scores. Persistence, development, or recurrence of comorbidities such as recurrent urinary tract infection (UTI), retention, stones, hematuria, and incontinence can also signal a failed MIST. Read More

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Laparoscopic removal of intravesically inserted transobturator tape.

Int Urogynecol J 2021 Jun 11. Epub 2021 Jun 11.

Department of Obstetrics and Gynecology, 1st Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.

Introduction And Hypothesis: The aim of this video is to provide a step-by-step description of our approach to the surgical management of intravesically localized transobturator tape after previous failure of repeated cystoscopic tape resection.

Methods: This video presents a patient with tape erosion to the urinary bladder after repeated cystoscopic tape resection, recurrent stone formation, and repeated lithotripsy, with recurrent urinary tract infections and overactive bladder (OAB) with urgency incontinence.

Results: During the laparoscopy procedure tape was identified in the left obturator muscle, cut near the obturator muscle, and dissected up to the bladder wall. Read More

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Identification of a tumor microenvironment-related seven-gene signature for predicting prognosis in bladder cancer.

BMC Cancer 2021 Jun 10;21(1):692. Epub 2021 Jun 10.

Department of Urology, Xiangya Hospital of Central South University, No.88 Xiangya Road, Changsha, 410008, Hunan, China.

Background: Accumulating evidences demonstrated tumor microenvironment (TME) of bladder cancer (BLCA) may play a pivotal role in modulating tumorigenesis, progression, and alteration of biological features. Currently we aimed to establish a prognostic model based on TME-related gene expression for guiding clinical management of BLCA.

Methods: We employed ESTIMATE algorithm to evaluate TME cell infiltration in BLCA. Read More

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Preoperative estimate of natural ureteral length based on computed tomography and/or plain radiography.

Sci Rep 2021 Jun 9;11(1):12202. Epub 2021 Jun 9.

Department of Urology, MacKay Memorial Hospital, No. 92, Sec. 2, Zhongshan N. Rd., Zhongshan Dist., Taipei City, 10449, Taiwan, ROC.

To predict natural ureter lengths based on clinical images. We reviewed our image database of patients who underwent multiphasic computed tomography urography from January 2019 to April 2020. Natural ureteral length (UL) was measured using a three-dimensional curved multiplanar reformation technique. Read More

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Neoadjuvant immunotherapy is reshaping cancer management across multiple tumour types: The future is now!

Eur J Cancer 2021 Jun 6;152:155-164. Epub 2021 Jun 6.

Princess Máxima Center, University Medical Center Utrecht, Heidelberglaan 25, 3584 Utrecht, the Netherlands. Electronic address:

The Italian Network for Tumor Biotherapy (Network Italiano per la Bioterapia dei Tumori [NIBIT]) Foundation hosted its annual 2020 Think Tank meeting virtually, at which representatives from academic, clinical, industry, philanthropic, and regulatory organisations discussed the role of neoadjuvant immunotherapy for the treatment of cancer. Although the number of neoadjuvant immunotherapeutic trials is increasing across all malignancies, the Think Tank focused its discussion on the status of neoadjuvant trials in cutaneous melanoma (CM), muscle-invasive urothelial bladder cancer (MIBC), head and neck squamous cell carcinoma (HNSCC), and pancreatic adenocarcinoma (PDAC). Neoadjuvant developments in CM are nothing short of trailblazing. Read More

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Using a novel breathable silicone adhesive (Sil2 technology) in stoma appliances to improve peristomal skin health: answering the key questions.

Fiona Le Ber

Br J Nurs 2021 Mar;30(Sup8):19-24

Clinical Nurse Specialist in Community Continence and Stoma Care, Queen's Nurse and Committee Member of the Royal College of Nursing Bladder and Bowel Forum, Jersey.

Fiona Le Ber answers some of the questions that stoma care nurses may have regarding this novel silicone adhesive based technology, which helps to avoid medical adhesive related skin injury (MARSI) and moisture-associated skin damage (MASD). Whereas hydrocolloid stoma appliances absorb moisture, this has a non-absorptive method of moisture management that prevents peristomal skin becoming damp and excoriated. Read More

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Intermittent catheterisation: the common complications.

Br J Community Nurs 2021 Jun;26(6):272-277

Doctor, Department of Epidemiology and Public Health, Faculty of Medicine of Tunis, Tunis, Tunisia.

Intermittent catheterisation (IC) has been in practice for more than 40 years and is considered the gold standard in the management of urinary retention in the neurological bladder. IC has many advantages over indwelling urethral or suprapubic catheterisation, including reducing the risk of infection, protecting the bladder and improving quality of life. However, complications can be caused by the practice of this technique, the most common of which is infection. Read More

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Managing intractable incontinence from a Yang-Monti channel in a case of enterocystoplasty with bladder neck closure - Challenges and a modified surgical technique.

Indian J Urol 2021 Apr-Jun;37(2):180-182. Epub 2021 Apr 1.

Department of Urology and Renal Transplantation, JIPMER, Puducherry, India.

Incontinence in the Mitrofanoff principle varies between 2% and 40% and is a challenging problem to treat. Incontinence is even more when a Yang-Monti channel is used with simultaneous enterocystoplasty, probably due to ineffective submucosal tunneling owing to the inferior quality of bowel mucosa. Here, we report the management options of such problems along with a novel surgical technique. Read More

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Mullerianosis of the urinary bladder; A case report.

Int J Surg Case Rep 2021 May 26;83:106040. Epub 2021 May 26.

Smart Health Tower, Madam Mitterrand Str, Sulaimani, Kurdistan, Iraq; Kscien Organization, Hamdi Str, Azadi Mall, Sulaimani, Kurdistan, Iraq.

Introduction: Mullerianosis is a sporadic condition of the urinary bladder. The study aims to present a case of mullerianosis with a brief literature review.

Case Presentation: A 52-year-old lady presented with hematuria for one-year duration. Read More

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Pulsed electromagnetic field (PEMF) as an adjunct therapy for pain management in interstitial cystitis/bladder pain syndrome.

Int Urogynecol J 2021 Jun 8. Epub 2021 Jun 8.

Wake Forest Institute for Regenerative Medicine, Wake Forest Baptist Medical Center, 391 Technology Way, Winston Salem, NC, 27101, USA.

Introduction And Hypothesis: Patients with interstitial cystitis/bladder pain syndrome (IC/BPS) often experience chronic pelvic and even systemic pain that can be difficult to clinically manage. Pulsed electromagnetic field (PEMF) therapy, a non-invasive strategy that has shown significant efficacy for pain reduction in other chronic pain conditions, may provide benefit for pain management in patients with IC/BPS.

Methods: PEMF delivery to patients occurs via a bio-electromagnetic-energy device which consists of a flexible mat (180 × 50 cm) that the patient lies on for systemic, full-body delivery and/or a flexible pad (50 × 15 cm) for targeted delivery to a specific body region (e. Read More

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[Side effects of immune checkpoint inhibitor treatment of urological tumors].

Urologe A 2021 Jun 8;60(6):803-815. Epub 2021 Jun 8.

Urologische Klinik und Poliklinik, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Deutschland.

Immune checkpoint inhibitors (ICI) are currently routinely used for the treatment of advanced or metastatic urothelial and renal cell carcinomas. Furthermore, several clinical trials are currently investigating their role in adjuvant and neoadjuvant settings as well as in high-risk non-muscle-invasive bladder cancer. As a result, urologists are increasingly confronted with patients who are currently receiving, have recently received or will receive ICI treatment. Read More

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Prospective cohort study on hospitalised patients with suspected urinary tract infection and risk factors por multidrug resistance.

Sci Rep 2021 Jun 7;11(1):11927. Epub 2021 Jun 7.

Infectious Disease Unit, University and Polytechnic Hospital La Fe, Valencia, Spain.

Urinary tract infections (UTIs) are among the most common bacterial infections and a frequent cause for hospitalization in the elderly. The aim of our study was to analyse epidemiological, microbiological, therapeutic, and prognostic of elderly hospitalised patients with and to determine independent risk factors for multidrug resistance and its outcome implications. A single-centre observational prospective cohort analysis of 163 adult patients hospitalized for suspected symptomatic UTI in the Departments of Internal Medicine, Infectious Diseases and Short-Stay Medical Unit of a tertiary hospital was conducted. Read More

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Role of Radiomics in the Prediction of Muscle-invasive Bladder Cancer: A Systematic Review and Meta-analysis.

Eur Urol Focus 2021 Jun 4. Epub 2021 Jun 4.

Urology Clinic, Centre of Postgraduate Medical Education, Department of Urology, Professor Witold Orlowski Independent Public Hospital, Warsaw, Poland.

Context: Radiomics is a field of science that aims to develop improved methods of medical image analysis by extracting a large number of quantitative features. New data have emerged on the successful application of radiomics and machine-learning techniques to the prediction of muscle-invasive bladder cancer (MIBC).

Objective: To systematically review the diagnostic performance of radiomic techniques in predicting MIBC. Read More

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Managing LUTS in primary care: Qualitative study of GPs' and patients' experiences.

Br J Gen Pract 2021 Jun 4. Epub 2021 Jun 4.

Cardiff University, Division of Population Medicine, School of Medicine, Cardiff, United Kingdom.

Background: Lower urinary tract symptoms (LUTS) are common in older men and impact considerably on their quality of life. Management can be complex, and although most LUTS could be treated effectively in primary care, referrals to urology outpatients are increasing. The experiences of General Practitioners (GPs) and patients relating to the management of LUTS have not yet been fully explored. Read More

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Machine Learning Methods to Identify Missed Cases of Bladder Cancer in Population-Based Registries.

JCO Clin Cancer Inform 2021 06;5:641-653

University of Michigan, Ann Arbor, MI.

Purpose: Population-based cancer incidence rates of bladder cancer may be underestimated. Accurate estimates are needed for understanding the burden of bladder cancer in the United States. We developed and evaluated the feasibility of a machine learning-based classifier to identify bladder cancer cases missed by cancer registries, and estimated the rate of bladder cancer cases potentially missed. Read More

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Mitrofanoff external continent urinary diversion in the management of bladder exstrophy-epispadias complex in adolescents.

Urol Case Rep 2021 Sep 19;38:101727. Epub 2021 May 19.

Urology Department, Academic Hospital Habib Bourguiba, Sfax, Tunisia.

Despite theadvancements in surgical reconstructive techniques for bladder exstrophy-epispadias complex, urinary incontinence represents a major problem that affects the quality of life. Bladder augmentation associated to Mitrofanoff external continent urinary diversion (ECUD) constitute for some surgeon the best solution for the management of bladder exstrophyallowing to achieve continence and to preserve renal function. Read More

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September 2021