22,969 results match your criteria Bladder Management

Factors associated with surgical repair success of female genital fistula in the Democratic Republic of Congo: Experiences of the Fistula Care Plus Project, 2017-2019.

Trop Med Int Health 2022 Jun 24. Epub 2022 Jun 24.

Centre National de Formation et de Recherche en Santé Rurale de Maferinyah, Forécariah, Guinea.

Objective: We sought to document outcomes and factors associated with surgical success in hospitals supported by the Fistula Care Plus Project in the DRC, 2017-2019.

Methods: This was a retrospective cohort study analyzing routine repair data on women with Female Genital Fistula. Univariate and multivariate analyses were conducted to determine factors associated with successful fistula repair. Read More

View Article and Full-Text PDF

Validation of a scoring system to predict bladder dysfunction after laparoscopic rectal cancer surgery.

Langenbecks Arch Surg 2022 Jun 24. Epub 2022 Jun 24.

Department of Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul, 03181, Republic of Korea.

Purpose: A recent trend in  urinary catheter management in patients who underwent laparoscopic rectal cancer surgery is early removal. However, some patients develop bladder dysfunction and require urinary re-catheterization. In 2016, a scoring system to predict bladder dysfunction after laparoscopic rectal cancer surgery was developed in our institution. Read More

View Article and Full-Text PDF

Pediatric Spina Bifida and Spinal Cord Injury.

J Pers Med 2022 Jun 17;12(6). Epub 2022 Jun 17.

Department of Physical Medicine and Rehabilitation, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.

Pediatric spina bifida (SB) and spinal cord injury (SCI) are unfortunately common in our society, and their unique findings and comorbidities warrant special consideration. This manuscript will discuss the epidemiology, pathophysiology, prevention, and management strategies for children growing and developing with these unique neuromuscular disorders. Growth and development of the maturing child places them at high risk of spinal cord tethering, syringomyelia, ascending paralysis, pressure injuries, and orthopedic abnormalities that must be addressed frequently and judiciously. Read More

View Article and Full-Text PDF

Neurogenic Bladder Physiology, Pathogenesis, and Management after Spinal Cord Injury.

J Pers Med 2022 Jun 14;12(6). Epub 2022 Jun 14.

Department of Physical Medicine and Rehabilitation, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

Urinary incontinence is common after spinal cord injury (SCI) due to loss of supraspinal coordination and unabated reflexes in both autonomic and somatic nervous systems; if unchecked, these disturbances can become life-threatening. This manuscript will review normal anatomy and physiology of the urinary system and discuss pathophysiology secondary to SCI. This includes a discussion of autonomic dysreflexia, as well as its diagnosis and management. Read More

View Article and Full-Text PDF

En-bloc Laser Resection of Bladder Tumors: Where Are We Now?

J Clin Med 2022 Jun 16;11(12). Epub 2022 Jun 16.

Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, Italy.

Transurethral resection of bladder tumors (TURBT) is a crucial procedure in the management of bladder cancer [... Read More

View Article and Full-Text PDF

Repetitive Transcranial Magnetic Stimulation of the Primary Motor Cortex beyond Motor Rehabilitation: A Review of the Current Evidence.

Brain Sci 2022 Jun 10;12(6). Epub 2022 Jun 10.

Department of Neurology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.

Transcranial magnetic stimulation (TMS) has emerged as a novel technique to stimulate the human brain through the scalp. Over the years, identifying the optimal brain region and stimulation parameters has been a subject of debate in the literature on therapeutic uses of repetitive TMS (rTMS). Nevertheless, the primary motor cortex (M1) has been a conventional target for rTMS to treat motor symptoms, such as hemiplegia and spasticity, as it controls the voluntary movement of the body. Read More

View Article and Full-Text PDF

Fetal and Newborn Management of Cloacal Malformations.

Children (Basel) 2022 Jun 14;9(6). Epub 2022 Jun 14.

Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, DC 20010, USA.

Cloaca is a rare, complex malformation encompassing the genitourinary and anorectal tract of the female in which these tracts fail to separate in utero, resulting in a single perineal orifice. Prenatal sonography detects a few cases with findings such as renal and urinary tract malformations, intraluminal calcifications, dilated bowel, ambiguous genitalia, a cystic pelvic mass, or identification of other associated anomalies prompting further imaging. Multi-disciplinary collaboration between neonatology, pediatric surgery, urology, and gynecology is paramount to achieving safe outcomes. Read More

View Article and Full-Text PDF

Rac1 as a Target to Treat Dysfunctions and Cancer of the Bladder.

Biomedicines 2022 Jun 8;10(6). Epub 2022 Jun 8.

OncoWitan, Scientific Consulting Office, 59290 Lille (Wasquehal), France.

Bladder pathologies, very common in the aged population, have a considerable negative impact on quality of life. Novel targets are needed to design drugs and combinations to treat diseases such as overactive bladder and bladder cancers. A promising new target is the ubiquitous Rho GTPase Rac1, frequently dysregulated and overexpressed in bladder pathologies. Read More

View Article and Full-Text PDF

Compact Smartphone-Based Laser Speckle Contrast Imaging Endoscope Device for Point-of-Care Blood Flow Monitoring.

Biosensors (Basel) 2022 Jun 9;12(6). Epub 2022 Jun 9.

Biomedical Engineering Research Center, Asan Institute for Life Science, Asan Medical Center, Seoul 05505, Korea.

Laser speckle contrast imaging (LSCI) is a powerful visualization tool for quantifying blood flow in tissues, providing simplicity of configuration, ease of use, and intuitive results. With recent advancements, smartphone and camera technologies are suitable for the development of smartphone-based LSCI applications for point-of-care (POC) diagnosis. A smartphone-based portable LSCI endoscope system was validated for POC diagnosis of vascular disorders. Read More

View Article and Full-Text PDF

Adherence to professional society guidelines among women with stress or mixed urinary incontinence.

Neurourol Urodyn 2022 Jun 22. Epub 2022 Jun 22.

Renovia, Inc., Boston, Massachusetts, USA.

Aims: The objective of this analysis was to describe longitudinal adherence with recommended urinary incontinence (UI) evaluation and treatment guidelines over a 2-year period in patients newly diagnosed with stress (SUI) or mixed UI (MUI), and average 2-year cost associated with initial treatment.

Methods: A retrospective claims analysis using the IBM MarketScan database was conducted. Women diagnosed with SUI/MUI between July 1, 2014 and June 30, 2016 were identified using the International Classification of Diseases (ICD) 9 and 10 codes for SUI or MUI. Read More

View Article and Full-Text PDF

Hyperbaric oxygen therapy as adjuvant treatment for surgical site infections after male-to-female gender affirmation surgery: A ten-year experience.

Andrology 2022 Jun 21. Epub 2022 Jun 21.

Urology Unit, Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.

Introduction: Several urological conditions that share an impairment of tissue oxygenation can benefit from hyperbaric oxygen therapy (HBO), limited evidence is available on the impact of HBO in patients undergoing male-to-female (MtF) Gender Affirmation Surgery (GAS).

Aim: To evaluate the efficacy and safety of HBO as adjuvant treatment for surgical site infections in patients undergoing MtF GAS.

Methods: This research was conducted as an observational retrospective study. Read More

View Article and Full-Text PDF

Radiologic Diagnosis and Staging of Bladder Cancer: An Update.

J Comput Assist Tomogr 2022 Jun 18. Epub 2022 Jun 18.

From the University of Texas MD Anderson Cancer Center, Houston, TX.

Although cystoscopic biopsy is the standard of care for initial diagnosis and local staging of bladder cancer, radiologic imaging plays a major role in identifying local invasion, nodal status, distant metastasis, and posttreatment surveillance. Recent development of the Vesical Imaging-Reporting and Data System for interpretation of multiparametric magnetic resonance imaging of the bladder has expanded the role diagnostic imaging in the management of bladder cancer. This article reviews multimodality imaging appearances, staging, and differential diagnosis of bladder cancer. Read More

View Article and Full-Text PDF

The Value of Preoperative Local Symptoms in Prognosis of Upper Tract Urothelial Carcinoma After Radical Nephroureterectomy: A Retrospective, Multicenter Cohort Study.

Front Oncol 2022 2;12:872849. Epub 2022 Jun 2.

Department of Urology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

Purpose: We aimed to evaluate the impact of preoperative local symptoms on prognosis after radical nephroureterectomy in patients with upper tract urothelial carcinoma (UTUC).

Methods: This retrospective study consisted of 2,662 UTUC patients treated at 15 institutions in Taiwan from 1988 to 2019. Clinicopathological data were retrospectively collected for analysis by the Taiwan UTUC Collaboration Group. Read More

View Article and Full-Text PDF

Immunotherapy With Bacillus Calmette-Guerin (BCG) in a 16-Year-Old With Urothelial Bladder Carcinoma.

Cureus 2022 May 14;14(5):e24994. Epub 2022 May 14.

School of Medicine, Universidad Anahuac Mexico, Mexico City, MEX.

Urothelial bladder cancer (UBC) is an exceptionally rare condition in adolescents between 15 and 19 years of age. Typically, adolescents and pediatric patients with UBC are more likely to have a favorable histological report. The aim of the paper is to report our experience in the management of a 16-year-old patient with UBC with no risk factors that came to the office because of a history of painless gross hematuria. Read More

View Article and Full-Text PDF

Web-Based Prediction Models for Overall Survival and Cancer-Specific Survival of Patients With Primary Urachal Carcinoma: A Study Based on SEER Database.

Front Public Health 2022 2;10:870920. Epub 2022 Jun 2.

Department of Urology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.

Objective: We aimed to establish nomograms to predict the overall survival (OS) and cancer-specific survival (CSS) of patients with primary urachal carcinoma (UrC).

Methods: Information on patients diagnosed with UrC from 1975 to 2018 was collected from the Surveillance, Epidemiology, and End Results (SEER) Program Research Data. The independent prognostic factors were determined using univariate and multivariate Cox regression. Read More

View Article and Full-Text PDF

A Robust Immuno-Prognostic Model of Non-Muscle-Invasive Bladder Cancer Indicates Dynamic Interaction in Tumor Immune Microenvironment Contributes to Cancer Progression.

Front Genet 2022 3;13:833989. Epub 2022 Jun 3.

Institutes of Biomedical Sciences and School of Basic Medical Sciences, Fudan University, Shanghai, China.

Non-muscle-invasive bladder cancer (NMIBC) accounts for more than 70% of urothelial cancer. More than half of NMIBC patients experience recurrence, progression, or metastasis, which essentially reduces life quality and survival time. Identifying the high-risk patients prone to progression remains the primary concern of risk management of NMIBC. Read More

View Article and Full-Text PDF

Identification of Feature Genes of a Novel Neural Network Model for Bladder Cancer.

Front Genet 2022 1;13:912171. Epub 2022 Jun 1.

Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

The combination of deep learning methods and oncogenomics can provide an effective diagnostic method for malignant tumors; thus, we attempted to construct a reliable artificial neural network model as a novel diagnostic tool for Bladder cancer (BLCA). Three expression profiling datasets (GSE61615, GSE65635, and GSE100926) were downloaded from the Gene Expression Omnibus (GEO) database. GSE61615 and GSE65635 were taken as the train group, while GSE100926 was set as the test group. Read More

View Article and Full-Text PDF

Intermediate-risk Non-muscle-invasive Bladder Cancer: Updated Consensus Definition and Management Recommendations from the International Bladder Cancer Group.

Eur Urol Oncol 2022 Jun 16. Epub 2022 Jun 16.

Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

Context: Intermediate-risk (IR) non-muscle-invasive bladder cancer (NMIBC) is a heterogeneous disease.

Objective: To update the International Bladder Cancer Group (IBCG) guidance and provide practical recommendations on IR NMIBC management.

Evidence Acquisition: A collaborative review of published randomized clinical trials, meta-analyses, systematic reviews, and clinical practice guidance on IR NMIBC published before January 2022 was undertaken using PubMed/Medline. Read More

View Article and Full-Text PDF

Status of Hospital Infection Prevention Practices in Thailand in the Era of COVID-19: Results from a National Survey.

Am J Infect Control 2022 Jun 16. Epub 2022 Jun 16.

Division of Infectious Diseases, Thammasart University Hospital, Pratumthani, Thailand. Electronic address:

Background: . A 2014 study assessed infection prevention (IP) practices in Thai hospitals for catheter-associated urinary tract infection (CAUTI), central line-associated bloodstream infection (CLABSI), and ventilator-associated pneumonia (VAP). This study compares current IP practices to results obtained in 2014. Read More

View Article and Full-Text PDF

Subjective Outcome after Discontinuation of Botulinum Toxin-A Detrusor Injection for Lower Urinary Tract Disorders: The Majority Suffers!

Urol Int 2022 Jun 17:1-10. Epub 2022 Jun 17.

Department of Urology, Charité - University Hospital Berlin, Berlin, Germany.

Introduction: According to the EAU guidelines, botulinum toxin type A (BoNT-A) detrusor injections are one of the last options in the management of overactive bladder before opting for invasive surgery. So far, there have been no studies dedicated exclusively to such patients who have undergone this treatment and in whom this treatment has presumably failed. From the patient's point of view, there are questions regarding what reasons led to discontinuation, how patients perceive their BoNT-A treatment in hindsight, what further treatment do these patients receive, and how satisfied such patients are with their current situation. Read More

View Article and Full-Text PDF

18F-Fluorodeoxyglucose-PET-Computerized Tomography and non-Fluorodeoxyglucose PET-Computerized Tomography in Hepatobiliary and Pancreatic Malignancies.

PET Clin 2022 Jul;17(3):369-388

University College London Hospitals NHS Foundation Trust, London, United Kingdom.

Molecular imaging with PET-computerized tomography (PET-CT) plays an important role in oncology. There is current and evolving evidence supporting the use of fluorodeoxyglucose (FDG) and non-FDG tracers in assessment patients with hepatobiliary and pancreatic cancers in various clinical scenarios. In this chapter, we discuss the advantages and limitations of FDG and non-FDG PET-CT in the management of patients with hepatobiliary and pancreatic cancers. Read More

View Article and Full-Text PDF

Precursors of Urinary Bladder Cancer: Molecular Alterations and Biomarkers.

Hum Pathol 2022 Jun 15. Epub 2022 Jun 15.

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA; Michigan Center for Translational Pathology, Ann Arbor, MI, USA. Electronic address:

Clinical surveillance and follow-up of patients diagnosed with or at risk for urinary bladder cancers represent long-term, invasive, and costly processes for which supplemental biomarker information could help provide objective, personalized risk assessment. In particular, there are several precursors and possible precursors to urinary bladder cancer for which clinical behavior is heterogenous and interobserver variability in histopathologic diagnosis make it difficult to standardize management. This review seeks to highlight these precursor lesions from a diagnostic perspective (including flat urothelial lesions, papillary urothelial lesions, squamous lesions, and glandular lesions) and qualify known multi-omic biomarkers that may help explain their behavior, predict patient risk, and acknowledge the nuance inherent to the question of whether these lesions are "benign" or "preneoplastic. Read More

View Article and Full-Text PDF

Prognostic implication of TERT promoter mutation and circulating tumor cells in muscle-invasive bladder cancer.

World J Urol 2022 Jun 17. Epub 2022 Jun 17.

Laboratori i Servei d Urologia, Hospital Clínic de Barcelona, Barcelona, Spain.

Purpose: Current clinical prognostic factors are not accurate enough to identify and monitor those muscle-invasive bladder cancer (MIBC) patients at high risk of progression after radical cystectomy (RC). Here, we determined genetic alterations in the tumor and circulating tumor cell (CTC) enumeration to find biomarkers useful for the management of MIBC after RC.

Methods: Thirty-nine MIBC patients undergoing RC were included. Read More

View Article and Full-Text PDF

Use of ginger to control nausea and vomiting caused by chemotherapy in patients with cervical cancer undergoing treatment: An experiment.

Medicine (Baltimore) 2022 Jun 17;101(24):e29403. Epub 2022 Jun 17.

Nursing Graduate Program, Federal University of Rio Grande do Norte, Natal, Brazil.

Introduction: Uterine cervix tumors have an invasive nature, with the capacity to proliferate to surrounding organs such as the vagina, bladder, and rectum, as well as the capacity for dissemination and involvement of structures distant from its place of origin. According to the International Federation of Gynecology and Obstetrics, patients with stages IB I, IB I microscopic (small dimension <4 cm) are indicated for radiotherapy or adjuvant chemoradiotherapy with cisplatin (40 mg/m2). However, cisplatin has side effects such as hematological implications (anemia, neutropenia, and thrombocytopenia), gastrointestinal disorders (nausea, vomiting, diarrhea, constipation), and fatigue. Read More

View Article and Full-Text PDF

Experiences in managing different consequences of forgotten ureteral stents.

Urol Ann 2022 Apr-Jun;14(2):141-146. Epub 2022 Feb 15.

Department of Urology, Minimally Invasive Surgery Center, Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Purpose: We reported the different consequences of forgotten stents and share our managing experiences.

Patients And Methods: From July 2011 to August 2019, eight patients (five men and three women) with forgotten encrusted ureteral stents were treated by different endoscopic procedures in our center. Plain-film radiography (kidney, ureter, and bladder [KUB]) and computed tomography were used to evaluate the position of stents, the site of encrustation, and the stone burden. Read More

View Article and Full-Text PDF
February 2022

Non-inferior and more feasible transcutaneous tibial nerve stimulation in treating overactive bladder: A systematic review and meta-analysis.

Int J Urol 2022 Jun 16. Epub 2022 Jun 16.

Department of Urology, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, Saudi Arabia.

Objectives: Overactive bladder (OAB) is identified as a urinary urgency accompanied by frequency and nocturia with or without urgency urinary incontinence in the nonexistence of a urinary tract infection or other evident pathologies. This systematic review and meta-analysis aimed to evaluate the efficacy of the transcutaneous tibial nerve stimulation (TTNS) versus percutaneous tibial nerve stimulation (PTNS) or anticholinergic drugs in reducing symptoms and improving the quality of life for OAB patients.

Methods: We performed a systematic search in Medline, Embase, and CENTRAL, in which we included randomized controlled trials that compared TTNS with anticholinergic drugs or PTNS in treating idiopathic OAB. Read More

View Article and Full-Text PDF

Case of metachronous clear cell bladder metastasis on low risk localized renal cell carcinoma patient.

Int J Surg Case Rep 2022 May 6;96:107158. Epub 2022 May 6.

Department of Anatomical Pathology, Hasan Sadikin Academic Medical Center - Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.

Introduction: Renal cell carcinoma (RCC) is well known for its ability to metastasize into different organs. However, the management of metachronous RCC is still not yet standardized.

Case Presentation: A 62 years old man was presented with haematuria for the last 2 months. Read More

View Article and Full-Text PDF

Mesenchymal neoplasms of the urinary bladder: a comprehensive review with focus on cross-sectional imaging findings.

Abdom Radiol (NY) 2022 Jun 15. Epub 2022 Jun 15.

Department of Abdominal Imaging, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1473, Houston, TX, 77030, USA.

Mesenchymal neoplasms of the urinary bladder are exceedingly rare and display remarkable diversity. These tumors demonstrate distinct pathological features as well as variable biological behavior and cross-sectional imaging findings. The rarity of tumors, nonspecific symptoms and seemingly normal cystoscopic findings (particularly with small and exophytic tumors) frequently lead to misdiagnosis or missed diagnosis. Read More

View Article and Full-Text PDF

Bladder augmentation in exstrophy vesicae: Long-term results of a single experienced center.

Birth Defects Res 2022 Jun 15. Epub 2022 Jun 15.

Department of Pediatric Surgery, Başakşehir Çam and Sakura City Hospital/Health Sciences University, İstanbul, Turkey.

Background: In this study, we present our long-term treatment outcomes of bladder augmentation (BA), bladder neck closure, and Mitrofanoff clean intermittent catheterization (CIC) in managing bladder exstrophy (BE).

Methods: This was a retrospective medical records' review of 33 children diagnosed as born with BE, followed up at a tertiary pediatric urology clinic from 1988 to 2020. Outcomes such as surgical interventions, presence of renal calculi, hydronephrosis, and continence status were extracted. Read More

View Article and Full-Text PDF

Intravesical MgSO for the treatment of BCG refractory T1 G3 bladder cancer: Preliminary results on efficacy and safety.

Intractable Rare Dis Res 2022 May;11(2):81-83

Department of Urology, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris Descartes University, Paris, France.

An urgent need of therapy exists for patients with high-risk non-muscle invasive bladder cancer (NMIBC) for whom Bacillus Calmette-Guérin (BCG) refractory treatment has failed. We investigated the role of intravesical magnesium sulfate (MgSO) therapy in the management of BCG refractory T1 high grade (G3) NMIBC. Between January 2018 and July 2021, we performed a prospective trial enrolling participants with T1 G3 NMIBC refractory in BCG therapy. Read More

View Article and Full-Text PDF