25,723 results match your criteria Bites Human


Understanding the Connections Between Dogs, Health and Inuit Through a Mixed-Methods Study.

Ecohealth 2018 Dec 14. Epub 2018 Dec 14.

Groupe de recherche en épidémiologie des zoonoses et santé publique, Université de Montréal, 3200 Sicotte, Saint-Hyacinthe, QC, J2S 7C6, Canada.

Dogs have been an integral part of the Inuit social and cultural environment for generations, but their presence also generates public health risks such as bites and exposure to zoonotic diseases such as rabies. In Nunavik, Canada, some prevention and control interventions targeting dogs have been implemented but have not demonstrated their effectiveness in a long-term sustainable perspective. This study was conducted in one Inuit community of Nunavik and used mixed methods to get a better understanding of factors that affect human and dog health, dog-related risks for humans and perceptions of dogs in Inuit communities using an interdisciplinary perspective in line with the Ecohealth approach. Read More

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December 2018

Snakebite Mitigation Project of the Madras Crocodile Bank/Centre for Herpetology, India: background and a brief summary of activities.

Authors:
Romulus Whitaker

Trans R Soc Trop Med Hyg 2018 Dec 14. Epub 2018 Dec 14.

Project Manager (India), Global Snakebite Initiative, East Coast Road, Mamallapuram, Chennai, India.

Snakebite is a serious problem in rural India where several highly venomous species are commonly found in and around agricultural areas where prey such as rodents and amphibians are abundant. Four snake species, referred to as the Big Four, are responsible for the most serious and fatal bites: spectacled cobra (Naja naja), Russell's viper (Daboia russelii), common krait (Bungarus caeruleus) and saw-scaled viper (Echis carinatus). A polyvalent antivenom is made to treat these bites but public awareness and distribution of this life-saving drug is inadequate. Read More

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December 2018

Effectiveness of repellent delivered through village health volunteers on malaria incidence in villages in South-East Myanmar: a stepped-wedge cluster-randomised controlled trial protocol.

BMC Infect Dis 2018 Dec 14;18(1):663. Epub 2018 Dec 14.

Burnet Institute, Melbourne, Australia.

Background: To combat emerging drug resistance in the Greater Mekong Sub-region (GMS) the World Health Organization and GMS countries have committed to eliminating malaria in the region by 2030. The overall approach includes providing universal access to diagnosis and treatment of malaria, and sustainable preventive measures, including vector control. Topical repellents are an intervention that can be used to target residual malaria transmission not covered by long lasting insecticide nets and indoor residual spraying. Read More

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December 2018

Combined effects of flow speed and sub-lethal insecticide exposure on predator-prey interactions between the California killifish and an infaunal polychaete.

Ecotoxicology 2018 Dec 13. Epub 2018 Dec 13.

Department of Biology and Coastal and Marine Institute, San Diego State University, 5500 Campanile Drive, San Diego, CA, 92182-4614, USA.

Hydrodynamics and pollution affect estuarine populations, but their ecological effects have rarely been studied in combination. We conducted two laboratory experiments to quantify whether predator-prey interactions between California killifish, Fundulus parvipinnis, and the polychaete Polydora cornuta vary with flow speed and chlorpyrifos exposure. In one experiment, only F. Read More

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December 2018

Saliva Induces Heme Oxygenase-1 Expression at Bite Sites.

Front Immunol 2018 28;9:2779. Epub 2018 Nov 28.

Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Brazil.

Sand flies bite mammalian hosts to obtain a blood meal, driving changes in the host inflammatory response that support the establishment of infection. This effect is partially attributed to components of sand fly saliva, which are able to recruit and activate leukocytes. Our group has shown that heme oxygenase-1 (HO-1) favors survival in infected cells by reducing inflammatory responses. Read More

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November 2018

Host-specific expression of Ixodes scapularis salivary genes.

Ticks Tick Borne Dis 2018 Dec 3. Epub 2018 Dec 3.

Section of Infectious Diseases, New Haven, CT, 06520, USA; Howard Hughes Medical Institute, Chevy Chase, Maryland, 20815, USA.

Ixodes scapularis vectors several pathogens including Borrelia burgdorferi, the agent of Lyme disease. Nymphal and larval stages, and the pathogens transmitted by I. scapularis are maintained in a zoonotic cycle involving rodent reservoir hosts, predominantly Peromyscus leucopus. Read More

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December 2018

Kidney injury following envenoming by hump-nosed pit viper (Genus: Hypnale) in Sri Lanka: proven and probable cases.

Trans R Soc Trop Med Hyg 2018 Dec 13. Epub 2018 Dec 13.

Department of Medicine, Faculty of Medicine, University of Peradeniya, Sri Lanka.

Background: Hump-nosed pit vipers (Hypnale hypnale) are highly venomous snakes found in Sri Lanka and the Western Ghats region of India. They are the most common cause of venomous snakebites in Sri Lanka, mainly causing local envenoming leading to pain, swelling and necrosis. Systemic envenoming causing acute kidney injury and coagulopathy are more commonly recognized following their bites. Read More

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December 2018
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Identification and characterization of the causative triatomine bugs of anaphylactic shock in Zhanjiang, China.

Infect Dis Poverty 2018 Dec 11;7(1):127. Epub 2018 Dec 11.

Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.

Background: Two health concerns primarily related to triatomine bugs are transmission of Trypanosoma cruzi through infective feces, and allergic reactions induced by triatomine bites. In the Southwestern United States, reduviid bugs bites commonly cause insect allergy. In South China, four cases of anaphylactic shock have been reported after this bite exposure. Read More

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December 2018

[Rabies knowledge, attitudes, and practices of human and animal healthcare providers in Chad].

Sante Publique 2018 May June;30(3):418-428

Introduction: Rabies, an infectious disease mainly transmitted by dog bites, is fatal due to lack of appropriate knowledge-attitudes-practices (KAP). The KAP of healthcare providers are particularly important because of their presence in the communities and their profession and were evaluated in the present study.

Methods: A cross-sectional, questionnaire-based descriptive study was conducted in healthcare providers recruited from four health districts in Chad in 2015. Read More

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December 2018
1 Read

Teaching Children and Parents to Understand Dog Signaling.

Front Vet Sci 2018 20;5:257. Epub 2018 Nov 20.

Department Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium.

Safe human-dog relationships require understanding of dogs' signaling. As children are at particularly high risk of dog bites, we investigated longitudinally how children from 3 to 5 years and parents perceive and interpret dogs' distress signaling gestures. All participants were then taught how to link their perception of the dog with the correct interpretation of dogs' behavioral signals and tested again. Read More

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November 2018
1 Read

The evolutionary relationship between beak shape, mechanical advantage, and feeding ecology in modern birds.

Evolution 2018 Dec 8. Epub 2018 Dec 8.

School of Earth Sciences, University of Bristol, Life Sciences Building, Bristol, UK.

Extensive research on avian adaptive radiations has led to a presumption that beak morphology predicts feeding ecology in birds. However, this ecomorphological relationship has only been quantified in a handful of avian lineages, where associations are of variable strength, and never at a broad macroevolutionary scale. Here, we used shape analysis and phylogenetic comparative methods to quantify the relationships between beak shape, mechanical advantage, and two measures of feeding ecology (feeding behaviour and semi-quantitative dietary preferences) in a broad sample of modern birds, comprising most living orders. Read More

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December 2018
1 Read

Modeling the Transmission Dynamics of Rabies for Dog, Chinese Ferret Badger and Human Interactions in Zhejiang Province, China.

Bull Math Biol 2018 Dec 10. Epub 2018 Dec 10.

School of Mathematics and Statistics, Central China Normal University, Wuhan, 430079, People's Republic of China.

Human rabies is one of the major public health problems in China with an average of 1977 cases per year. It is estimated that 95% of these human rabies cases are due to dog bites. In recent years, the number of wildlife-associated human rabies cases has increased, particularly in the southeast and northeast regions of mainland China. Read More

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December 2018

Screening of mosquitoes for filarioid helminths in urban areas in south western Poland-common patterns in European Setaria tundra xenomonitoring studies.

Parasitol Res 2018 Dec 8. Epub 2018 Dec 8.

Department of Influenza Research, National Influenza Center, National Institute of Public Health - National Institute of Hygiene, Chocimska 24, 00-791, Warszawa, Poland.

In recent years, numerous studies screening mosquitoes for filarioid helminths (xenomonitoring) have been performed in Europe. The entomological monitoring of filarial nematode infections in mosquitoes by molecular xenomonitoring might serve as the measure of the rate at which humans and animals expose mosquitoes to microfilariae and the rate at which animals and humans are exposed to the bites of the infected mosquitoes. We hypothesized that combining the data obtained from molecular xenomonitoring and phenological studies of mosquitoes in the urban environment would provide insights into the transmission risk of filarial diseases. Read More

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December 2018
1 Read

[Chikungunya, emerging disease in Latin America. Description of the first cases in Chile].

Rev Chilena Infectol 2018 Aug;35(4):413-419

Laboratorio de Infectología y Virología Molecular, Pontificia Universidad Católica de Chile, Chile.

Background: Chikungunya (CHIK) was introduced in The Americas in 2013, spreading rapidly. In 2014, the first imported case was diagnosed in Chile.

Aim: To identify patients with clinical suspicion of CHIK and describe their clinical and laboratory characteristics. Read More

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Total Nose and Upper Lip Replantation: A Case Report and Literature Review.

Plast Reconstr Surg Glob Open 2018 Oct 3;6(10):e1839. Epub 2018 Oct 3.

Division of Plastic Surgery, University of Alberta, Edmonton, Alberta, Canada.

The nose plays a critical role in olfaction, air filtration and humidification, and facial aesthetics. Most nasal amputations result from animal bites, human bites, and lacerations from glass. Successful replantation yields the best aesthetic and functional outcomes and is preferred compared with multistage nasal reconstruction. Read More

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October 2018
1 Read

Evaluation of the possible use of genus Mentha derived essential oils in the prevention of SENLAT syndrome caused by Rickettsia slovaca.

J Ethnopharmacol 2018 Dec 5. Epub 2018 Dec 5.

Biomedical Research Center, Institute of Virology, Slovak Academy of Sciences, Dúbravská cesta 9, 845 05 Bratislava, Slovakia.

Ethnopharmacological Relevance: Essential oils and essential oil bearing medicinal and culinary plants have a long tradition of being used to combat infection, treat various conditions, and promote and restore health. Mint oils are traditionally applied to repel insects and treat various conditions including wounds, skin infections, inflammation, eczema, urticaria, psoriasis, scabies and insect bites. They are among essential oils promoted as a natural way to prevent tick-borne diseases and recommended as ingredients in various homemade repellent mixtures and tick-bite treatments. Read More

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December 2018

Stepping into a dangerous quagmire: Macroecological determinants of Bothrops envenomings, Brazilian Amazon.

PLoS One 2018 6;13(12):e0208532. Epub 2018 Dec 6.

Escola Superior de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Brazil.

Despite significant and successful efforts in Brazil regarding snakebites in the areas of research, antivenom manufacture and quality control, training of health professionals in the diagnosis and clinical management of bites, little is known about determinants of snakebites incidence in order to further plan interventions to reduce the impact of this medical condition. Understanding the complexity of ecological interactions in a geographical region is important for prediction, prevention and control measures of snakebites. This investigation aims to describe spatial distribution and identify environmental determinants of human envenoming by lancehead pit vipers (Bothrops genus), in the Brazilian Amazon. Read More

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December 2018
1 Read

Age trends in asymptomatic and symptomatic Leishmania donovani infection in the Indian subcontinent: A review and analysis of data from diagnostic and epidemiological studies.

PLoS Negl Trop Dis 2018 Dec 6;12(12):e0006803. Epub 2018 Dec 6.

Zeeman Institute, University of Warwick, Coventry, United Kingdom.

Background: Age patterns in asymptomatic and symptomatic infection with Leishmania donovani, the causative agent of visceral leishmaniasis (VL) in the Indian subcontinent (ISC), are currently poorly understood. Age-stratified serology and infection incidence have been used to assess transmission levels of other diseases, which suggests that they may also be of use for monitoring and targeting control programmes to achieve elimination of VL and should be included in VL transmission dynamic models. We therefore analysed available age-stratified data on both disease incidence and prevalence of immune markers with the aim of collating the currently available data, estimating rates of infection, and informing modelling and future data collection. Read More

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December 2018
3 Reads

Reasons for Declining Venom Immunotherapy.

Acta Med Port 2018 Nov 30;31(11):618-623. Epub 2018 Nov 30.

Serviço de Imunoalergologia. Centro Hospitalar de São João. Porto. Portugal.

Introduction: Hymenoptera venom allergy is associated with significant morbidity and deterioration in health-related quality of life, and risk of fatal systemic reactions. Although venom immunotherapy is safe and the only effective treatment in allergic individuals, some patients prefer not to pursue this treatment. Since 2011, when the 50% reimbursement was stopped, patients must fully support the cost of immunotherapy. Read More

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November 2018
2 Reads

T-cell Activating Tribodies as a Novel Approach for Efficient Killing of ErbB2-positive Cancer Cells.

J Immunother 2019 Jan;42(1):1-10

Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II.

The Tyrosine Kinase Receptor ErbB2 (HER2) when overexpressed in breast cancer (BC) is associated with poor prognosis. The monoclonal antibody Trastuzumab has become a standard treatment of ErbB2+BC. The antibody treatment has limited efficacy, often meets resistance and induces cardiotoxicity. Read More

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January 2019
3 Reads

A case of ulceroglandular tularemia presenting with lymphadenopathy and an ulcer on a linear morphoea lesion surrounded by erysipelas.

Int Med Case Rep J 2018 12;11:313-318. Epub 2018 Nov 12.

Department of Infectious Diseases, Regional Hospital of Bellinzona e Valli, 6500 Bellinzona, Ticino, Switzerland.

Tularemia is a zoonosis caused by the infection of (a gram-negative aerobic bacterium). Transmission to other animals or humans usually occurs through insect or tick bites, direct contact with a contaminated environment (mud or water), infected animals - mainly lagomorphs - or by ingesting undercooked meat or inhaling contaminated dust (hay or soil). This paper discusses the case of a 32-year-old man, who came to our Emergency Room presenting with persistent fever, inguinal lymphadenopathy, and an ulcer on his left lower limb on a linear morphoea lesion that had been there for some time. Read More

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November 2018
1 Read

Bites that Spur the Blues: Maculae Ceruleae.

Am J Med 2018 Nov 29. Epub 2018 Nov 29.

Department of Dermatology, University of Minnesota, Minneapolis, MN.

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November 2018
1 Read

Unintended Consequences: A Review of Pharmacologically-Induced Priapism.

Sex Med Rev 2018 Nov 28. Epub 2018 Nov 28.

Department of Urology, Tulane University, New Orleans, LA, USA. Electronic address:

Background: Priapism has been linked to many commonly prescribed medications, as well as recreational drugs and toxins. Although the incidence of priapism as a result of medication is small, the increasing use of antidepressants, antipsychotics, and recreational drugs may lead to more cases of pharmacologically-induced priapism in the future.

Aim: To provide a comprehensive, up-to-date review of the most common causes of pharmacologically induced priapism and discuss incidence, pathophysiology, and basic management strategies. Read More

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November 2018
1 Read

Human rabies: evaluation of post-exposure prophylaxis prevalence in Ceará, Brazil, 2007-2015.

Epidemiol Serv Saude 2018 Nov 29;27(4):e2017547. Epub 2018 Nov 29.

Universidade Federal do Ceará, Departamento de Saúde Comunitária, Fortaleza, CE, Brasil.

Objective: to analyze the prevalence of inadequate human anti-rabies post-exposure prophylaxis in patients attacked by animals in the state of Ceará, Brazil, 2007-2015.

Methods: this was a study of the prevalence of inadequate prophylaxis procedures, using data on reported cases of accidents involving animals potentially capable of transmitting rabies registered on the Notifiable Diseases Information System (SINAN) from January 2007 to December 2015.

Results: of the 231,694 reported cases, 95. Read More

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November 2018
2 Reads

Reduced Eating Pace (RePace) Behavioral Intervention for Children Prone to or with Obesity: Does the Turtle Win the Race?

Obesity (Silver Spring) 2018 Dec 4. Epub 2018 Dec 4.

Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Objective: Rapid eating is a risk factor for childhood obesity but has not been a focus of intervention with young children. The short-term effects of a novel family-based treatment, "Reduced Eating Pace" (RePace), were tested on child eating speed and secondary outcomes.

Methods: Twenty-eight rapid eating children were randomized to RePace (n  = 14) or Delayed Usual Care Control (DUC) (n  = 14). Read More

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December 2018
4 Reads

An updated meta-analysis of the distribution and prevalence of Borrelia burgdorferi s.l. in ticks in Europe.

Int J Health Geogr 2018 Dec 4;17(1):41. Epub 2018 Dec 4.

Department of Parasitology and Parasitic Diseases, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Cluj-Napoca, Romania.

Background: The bacteria of the group Borrelia burgdorferi s.l. are the etiological agents of Lyme borreliosis in humans, transmitted by bites of ticks. Read More

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December 2018
3 Reads

Productive Propagation of Rift Valley Fever Phlebovirus Vaccine Strain MP-12 in Rousettus aegyptiacus Fruit Bats.

Viruses 2018 Nov 30;10(12). Epub 2018 Nov 30.

Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany.

Rift Valley fever phlebovirus (RVFV), the causative agent of an emerging zoonotic disease in Africa and Arabia, can infect a variety of species, predominantly ruminants, camelids, and humans. While clinical symptoms are mostly absent in adult ruminants and camelids, RVFV infection may lead to a serious, sometimes fatal disease in humans. Virus transmissions between individuals and between species mainly occur through mosquito bites, but direct or even indirect contact with infectious materials may also result in infection. Read More

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November 2018
2 Reads

The Role of Telemedicine in the Management of Maxillofacial Trauma in Emergency Departments - Preliminary Results.

J Stomatol Oral Maxillofac Surg 2018 Dec 1. Epub 2018 Dec 1.

Department of Maxillofacial Surgery, Caen University Hospital, 14000 Caen, France; Caen Faculty of Medicine, University of Caen Basse Normandie, 14032 Caen Cedex 5, France; UNICAEN, EA7451 Equipe BioConnecT, Avenue de la Côte de Nacre, 14000 Caen, France.

New technologies have over the past forty years become widespread across all domains of basic and applied research particularly in health-related fields. Telemedicine is a form of remote medical practice using information and communication technologies. It connects one or more health professionals with other health professionals or with patients. Read More

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December 2018
2 Reads

Human antibody reaction against recombinant salivary proteins of Phlebotomus orientalis in Eastern Africa.

PLoS Negl Trop Dis 2018 Dec 4;12(12):e0006981. Epub 2018 Dec 4.

Department of Parasitology, Faculty of Science, Charles University, Prague, Czech Republic.

Background: Phlebotomus orientalis is a vector of Leishmania donovani, the causative agent of life threatening visceral leishmaniasis spread in Eastern Africa. During blood-feeding, sand fly females salivate into the skin of the host. Sand fly saliva contains a large variety of proteins, some of which elicit specific antibody responses in the bitten hosts. Read More

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December 2018
7 Reads

Adverse Events in the Efficacy of Crotalidae Polyvalent Immune Fab Antivenom vs Placebo in Recovery from Copperhead Snakebite Trial.

South Med J 2018 Dec;111(12):716-720

From the Division of Emergency Medicine, Washington University School of Medicine, St Louis, Missouri, the Division of Emergency Medicine, Duke University, Durham, North Carolina, the Department of Emergency Medicine, East Carolina University Brody School of Medicine, Greenville, North Carolina, the Department of Emergency Medicine, Virginia Commonwealth University, Richmond, the Department of Emergency Medicine, Baylor College of Medicine, Houston, Texas, the Department of Emergency Medicine, University of North Carolina, Chapel Hill, North Carolina, Texas A&M Health Sciences Center, Bryan, Rocky Mountain Poison & Drug Center, Denver, Colorado, the Department of Emergency Medicine, UT Southwestern Medical Center, Dallas, Texas, the Department of Emergency Medicine, Augusta University, Augusta, Georgia, the Department of Emergency Medicine, University of Virginia, Charlottesville, the Department of Surgery, East Carolina University Brody School of Medicine, Greenville, North Carolina, and the Department of Surgery, Marshall University, Huntington, West Virginia.

Objective: To compare the incidence of hypersensitivity reactions following copperhead envenomation treated with Fab antivenom (FabAV) or placebo.

Methods: Patients with copperhead snakebites received treatment and follow-up in a prospective, randomized, double-blind, placebo-controlled trial of FabAV or placebo. The treatment allocation ratio was 2:1 (FabAV:placebo). Read More

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December 2018
3 Reads

Post-exposure prophylaxis vaccination rate and risk factors of human rabies in mainland China: a meta-analysis.

Epidemiol Infect 2018 Dec 4:1-6. Epub 2018 Dec 4.

Department of Epidemiology and Health Statistics,School of Public Health, Southeast University,Nanjing (210009),China.

Rabies is one of the major public health problems in China, and the mortality rate of rabies remains the highest among all notifiable infectious diseases. A meta-analysis was conducted to investigate the post-exposure prophylaxis (PEP) vaccination rate and risk factors for human rabies in mainland China. The PubMed, Web of Science, Chinese National Knowledge Infrastructure, Chinese Science and Technology Periodical and Wanfang databases were searched for articles on rabies vaccination status (published between 2007 and 2017). Read More

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December 2018
4 Reads

Antibiotic resistant zoonotic bacteria in Irrawaddy squirrel (Callosciurus pygerythrus).

Vet Med Sci 2018 Nov 29. Epub 2018 Nov 29.

Department of Microbiology and Veterinary Public Health, Chittagong Veterinary and Animal Sciences University (CVASU), Chittagong, Bangladesh.

Irrawaddy squirrel (Callosciurus pygerythrus) may play an important role in the transmission of zoonotic bacteria, but little is known about the carriage of zoonotic bacteria in this common frugivorous rodent in Bangladesh. We aimed to investigate the presence of common zoonotic bacterial pathogens in Irrawaddy squirrel in the southeast part of Bangladesh. A total of 27 rectal and 27 oro-nasal swabs were collected from 27 healthy wild Irrawaddy squirrels. Read More

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November 2018
4 Reads

Epstein-Barr virus and skin.

An Bras Dermatol 2018 Nov/Dec;93(6):786-799

Hospital Cayetano Heredia, Lima, Peru.

Epstein-Barr virus is a DNA virus infecting human beings and could affect 90% of human population. It is crucial to take in account that in Latin America, unlike what happens in developed countries, the exposure to the virus is very early and therefore people have a much longer interaction with the virus. The virus is related to many diseases, mainly the oncological ones, and when the onset is in cutaneous tissue, it can present many clinical variants, as well acute as chronic ones. Read More

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February 2018
1 Read

Spatial-temporal heterogeneity in malaria receptivity is best estimated by vector biting rates in areas nearing elimination.

Parasit Vectors 2018 Nov 27;11(1):606. Epub 2018 Nov 27.

James Cook University, Australian Institute of Tropical Health and Medicine, Cairns, QLD, 4870, Australia.

Background: Decisions on when vector control can be withdrawn after malaria is eliminated depend on the receptivity or potential of an area to support vector populations. To guide malaria control and elimination programmes, the potential of biting rates, sporozoite rates, entomological inoculation rates and parity rates to estimate malaria receptivity and transmission were compared within and among geographically localised villages of active transmission in the Western Province of the Solomon Islands.

Results: Malaria transmission and transmission potential was heterogeneous in both time and space both among and within villages as defined by anopheline species composition and biting densities. Read More

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November 2018

Snakebite envenomation in the Brazilian Amazon: a descriptive study.

Trans R Soc Trop Med Hyg 2018 Nov 24. Epub 2018 Nov 24.

Núcleo de Medicina Tropical (Tropical Medicine Centre), Universidade de Brasília (UnB), University Campus Darcy Ribeiro, Asa Norte, Brasília-DF, Brazil.

Snakebite envenomation in the Brazilian Amazon is a recognized public health problem that does not receive the appropriate attention from key stakeholders. The morbidity rate is relevant, but still underestimated. Thus, the present study updates the current state of knowledge on snakebite envenomation in the Brazilian Amazon. Read More

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November 2018
3 Reads

Perceptions of HIV transmission and pre-exposure prophylaxis among health care workers and community members in Rwanda.

PLoS One 2018 26;13(11):e0207650. Epub 2018 Nov 26.

Department of Medicine, University Teaching Hospital of Kigali, Kigali, Rwanda.

There are too many new HIV infections globally with 1.8 million persons infected in 2016 alone. Pre-exposure prophylaxis (PrEP) holds potential to decrease new infections and is synergistic with efforts currently in place to achieve an end to the AIDS epidemic in Sub-Saharan African, but uptake is limited. Read More

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November 2018

Pediatric Dog Bite Injuries in Central Texas.

J Pediatr Surg 2018 Oct 31. Epub 2018 Oct 31.

Texas A&M University Health Science Center, Temple, TX. Electronic address:

Purpose: Identify children at greatest risk for dog bite injuries and to provide injury prevention recommendations.

Methods: A retrospective review of patients aged ≤18 years treated for dog bite injuries from October 2011 to October 2016 was performed. Data collected included patient demographics, parental presence, time of injury, dog breed and ownership status, injury location and characteristics, need for operative intervention, and hospitalization. Read More

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October 2018
1 Read

First reported case of thrombocytopenia from a Heterodon nasicus envenomation.

Toxicon 2018 Nov 19;157:12-17. Epub 2018 Nov 19.

Rocky Mountain Poison and Drug Center - Denver Health and Hospital Authority, Denver, CO, USA.

Context: The vast majority of the 2.5 million annual worldwide venomous snakebites are attributed to Viperidae or Elapidae envenomations. Of the nearly 2000 Colubridae species described, only a handful are known to cause medically significant envenomations. Read More

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November 2018
1 Read

Exposure history, post-exposure prophylaxis use, and clinical characteristics of human rabies cases in China, 2006-2012.

Sci Rep 2018 Nov 21;8(1):17188. Epub 2018 Nov 21.

Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Rabies is still a public health threat in China. Evaluating the exposure history, clinical characteristics, and post-exposure prophylaxis (PEP) of the cases could help in identifying approaches to reducing the number of these preventable deaths. We analysed data collected from 10,971 case-investigations conducted in China from 2006 to 2012. Read More

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November 2018

A comparative study of the bispecific monoclonal antibody, blinatumomab expression in CHO cells and E. coli.

Prep Biochem Biotechnol 2018 Nov 21:1-7. Epub 2018 Nov 21.

b Biotechnology Research Center , Pasteur Institute of Iran , Tehran , Iran.

The "bispecifics" market improved over the past decade due to the development of many technological platforms including bispecific T cell engagers (BiTEs). The approval of blinatumomab, the most advanced bispecific T-cell engager (BiTE) in clinical trials, can be a significant milestone in the development of bispecific antibodies. Both Chinese hamster ovary (CHO) cells and E. Read More

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November 2018
13 Reads

Capnocytophaga canimorsus Capsular Serovar and Disease Severity, Helsinki Hospital District, Finland, 2000-2017.

Emerg Infect Dis 2018 Dec;24(12):2195-2201

We assembled a collection of 73 Capnocytophaga canimorsus isolates obtained from blood cultures taken from patients treated at Helsinki University Hospital (Helsinki, Finland) during 2000-2017. We serotyped these isolates by PCR and Western blot and attempted to correlate pathogen serovar with patient characteristics. Our analyses showed, in agreement with previous research, that 3 C. Read More

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December 2018

Interventions to prevent Lyme disease in humans: A systematic review.

Prev Med Rep 2019 Mar 13;13:16-22. Epub 2018 Nov 13.

EPPI-Centre, UCL Institute of Education, University College London, London, UK.

Lyme disease (LD) is an infection transferred to humans through bites from infected ticks. Surveillance indicates that the number of LD cases is increasing in the UK, therefore, improved knowledge about reducing transmission from ticks to humans is needed. Eighteen electronic databases were searched and additional web-based searching was conducted, to locate empirical research, published from 2002 onwards. Read More

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March 2019
8 Reads

Preventing tick bites - Educational resources.

Authors:
Jane Chiodini

Travel Med Infect Dis 2018 Nov - Dec;26:75-78. Epub 2018 Nov 16.

Amersham Vale Practice, London, UK. Electronic address:

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November 2018

Growth patterns and overbite depth indicators of long and short faces in Korean adolescents: Revisited through mixed-effects analysis.

Orthod Craniofac Res 2018 Nov 19. Epub 2018 Nov 19.

Department of Oral Anatomy, Dental Research Institute and School of Dentistry, Seoul National University, Seoul, Korea.

Objective: The purpose was to evaluate skeletal factors related to the growth of subjects with skeletal open and deep bites based on lateral cephalographs from 9 years of pure longitudinal data using mixed effect analysis.

Setting And Sample Population: Fifty-one children with extreme lower anterior facial height to total anterior facial height (LAFH/TAFH) ratio values at the age of 14 were assigned to either skeletal open bite or skeletal deep bite groups from a total of 223 subjects.

Material & Methods: The palatal plane angle (PPA), mandibular plane angle (MPA), gonial angle (GA), palatomandibular plane angle (PMA), upper gonial angle (UGA), lower gonial angle (LGA), occlusal plane angle (OPA) and overbite depth indicator (ODI) were measured and analysed. Read More

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November 2018
3 Reads

Are Dog Bites a Problem of Nature or Nurture?

Plast Surg (Oakv) 2018 Nov 3;26(4):297-298. Epub 2018 Oct 3.

University of British Columbia, Vancouver, British Columbia, Canada.

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November 2018

Dog Bites in Children: A Descriptive Analysis.

Plast Surg (Oakv) 2018 Nov 24;26(4):256-262. Epub 2018 Apr 24.

Division of Plastic Surgery, Dalhousie University, Halifax, Nova Scotia, Canada.

Objective: To describe characteristics of dog bites and their treatment in a pediatric population including infection, medical specialties involved, rates of admission, and need for surgery.

Method: Patients presenting with a dog bite to the emergency department of a tertiary care pediatric hospital between January 1, 2015, and June 30, 2017, were included. Details related to demographics, complications, consultations, and treatment were extracted from the patients' records. Read More

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November 2018
9 Reads

The results of cephalometric analysis in the dynamics of orthodontic treatment of patients with transversal anomalies of occlusion.

Wiad Lek 2018 ;71(7):1206-1213

Public Medical Establishment "Municipal Stomatological Polyclinic", Chernivtsi, Ukraine.

Objective: Introduction: This article discusses the problems of the current issue of modern orthodontics aimed at increasing the effectiveness of diagnosis and treatment of transversal anomalies of occlusion in patients in periods of alternating and permanent bites by using standard orthodontic equipment in combination with orthopedic treatment by physical rehabilitation methods. In this work, the features of cephalometric indices in patients with transversal anomalies of occlusion have been studied, which make it possible to approach the choice of orthodontic treatment method in a comprehensive way. The aim was to prove the efficiency of the combination of standard orthodontic equipment with orthopedic treatment by physical rehabilitation methods. Read More

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January 2018

Incidence of snakebites in 3 different geographic regions in Thua Thien Hue province, central Vietnam: Green pit vipers and cobras cause the majority of bites.

Toxicon 2018 Dec 15;156:61-65. Epub 2018 Nov 15.

Institute for Community Health Research, College of Medicine and Pharmacy, Hue University, Hue, Viet Nam.

Background: The annual incidence of snakebites in Vietnam is not known and only few publications about snakebite envenoming and medically relevant snakes can be found in English language literature. The present community-based surveys provide data on incidence of snakebites in three different geographic regions of Thua Thien Hue (TT Hue) province, central Vietnam and snake species responsible for bites in this region.

Methodology/results: The cross-sectional community based surveys were conducted from March to July 2017. Read More

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December 2018
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An unusual case of gross myoglobinuria in a child following Russell's viper (Daboia russelii) envenomation.

Toxicon 2018 Nov 16;157:77-79. Epub 2018 Nov 16.

Department of Medicine, Faculty of Medicine, University of Peradeniya, 20400, Sri Lanka.

Overt myoglobinuria associated with myotoxicity is a classic feature of sea snake envenomation. Russell's viper bites usually result in coagulopathy, neurotoxicity and nephrotoxicity but rarely myotoxicity has been reported, especially in the Sri Lankan variety (Daboia russelii). All those studies have demonstrated mild degree myotoxicity with microscopic level myoglobinuria. Read More

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November 2018
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Immunotherapy: A Novel Era of Promising Treatments for Multiple Myeloma.

Int J Mol Sci 2018 Nov 15;19(11). Epub 2018 Nov 15.

Department of Hematology, Hospital Clinic, IDIBAPS, 08036 Barcelona, Spain.

Multiple myeloma (MM) remains an incurable hematological malignancy characterized by clonal proliferation of malignant plasma cells in bone marrow. In the last 20 years, the introduction of autologous stem cell transplantation, followed by proteasome inhibitors and immunomodulatory agents, increased the survival of MM patients by 50%. However, still a high proportion of patients relapse and become refractory, especially, high-risk patients with adverse cytogenetics where these treatment combinations have shown limited benefit. Read More

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November 2018
7 Reads