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Animals (Basel) 2019 Apr 13;9(4). Epub 2019 Apr 13.

Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad Universitaria, D.F. México C.P. 04501, Mexico.

There is great need for veterinary care for working equids worldwide. Addressing this need provides an opportunity for veterinary students to gain primary care experience. An annual two week collaborative outreach and educational program with Michigan State University (MSU), the Universidad Nacional Autónoma de México (UNAM) and the Universidad Veracruzana (UV) was developed to provide care for working equids in rural Mexican communities. Read More

Health Place 2019 Apr 15;57:70-73. Epub 2019 Apr 15.

Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Canada; Faculty of Social Work, University of Calgary, Canada.

Despite calls for the adoption of 'One-Health' approaches, dog-bite injuries remain neglected in healthcare and public health, and our study may help to understand why. Media coverage can influence policy directions, including policies that address dogs. We collected articles (n = 65) published in two local newspapers, 2012-2017, then carried out an ethnographically-informed discourse analysis of the dog-bite reports. Read More

Exp Ther Med 2019 May 6;17(5):3768-3774. Epub 2019 Mar 6.

Department of Emergency, Southwest Hospital of the Third Military Medical University, Chongqing 400038, P.R. China.

bites are conventionally treated with animal-derived antivenom, the use of which is limited due to allergic reactions and serum sickness. Thus in the present study, the genes of humanized antibodies produced in response to venom were extracted from lymphocytes from patients bitten by . A single-chain variable fragment (scFv) library against venom was constructed using a T7 phage display system. Read More

Rev Prat 2019 Mar;69(3):320-323

Ancien professeur en pathologie infectieuse, École nationale vétérinaire, agroalimentaire et de l'alimentation de Nantes-Atlantique, Oniris, Nantes, France.

Risk of zoonoses by animal bites and scratches. The objectives of this study are to identify zoonosis risks related to animal bites and scratches in France. Pet-transmitted zoonoses, as pasteurellosis, cat scratches disease and various specific bacterial infections, are predominant, resulting usually in localized infections or, sometimes, in serious systemic infections (as those caused by Capnocytophaga canimorsus) in immunocompromised patients. Read More

BMC Infect Dis 2019 Apr 11;19(1):321. Epub 2019 Apr 11.

Pasteur Institute of Dakar, Epidemiology unit, Dakar, Senegal.

Background: Rabies remains a major public health problem in developing countries. Most fatal rabies cases, especially in children, result from dog bites and occur in low-income countries, such as those in Sub-Saharan Africa. Rabies can be controlled through mass dog vaccination and human deaths prevented through timely and appropriate post-exposure prophylaxis (PEP). Read More

JAAPA 2018 Apr;31(4):27-31

John B. Hurt is an assistant professor and director of clinical education in the PA program at Samford University in Birmingham, Ala. Kristopher R. Maday is program director of the PA program at the University of Tennessee Health Science Center in Memphis. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Animal bites account for 1% of ED visits and more than $50 million in healthcare costs annually in the United States. Managing bite wounds can be challenging and providers must consider the patient's tetanus status, species of animal inflicting the bite, and infection risk. This article describes treatment and care of bites and when rabies prophylaxis is indicated. Read More

Rev Med Suisse 2019 Apr;15(646):780-785

Service des maladies infectieuses, HUG, 1211 Genève 14.

Animal and human bites are a common cause of admission to the emergency room and the infections are common, although they are often trivialized. Complications can range from simple cellulitis to septic shock especially in asplenic patients with Capnoyctophaga canimorsus infection. Other less common infections are possible such as rat-bite fever, leptospirosis, tularemia, and evaluation of post-exposure prophylaxis (anti-tetanus, anti-rabies, HIV, HBV) is essential. Read More

Vet Microbiol 2019 Apr 23;231:80-86. Epub 2019 Feb 23.

National Veterinary Institute, Technical University of Denmark, Kemitorvet, DK-2800 Kgs Lyngby, Denmark. Electronic address:

The aim of the present study was to identify the animal prevalence and environmental reservoir of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) in mink farms. LA-MRSA on mink constitutes a human health hazard to farmers and farm workers, who handle the animals and are at risk of bites and scratches from colonized sites. The primary route of LA-MRSA colonization of mink is suspected to be by ingestion of contaminated pig by-products. Read More

Parasit Vectors 2019 Apr 3;12(1):154. Epub 2019 Apr 3.

UMR BIPAR, INRA, ANSES, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est, Maisons-Alfort, 94700, France.

This primer focuses on a recently diagnosed tick-borne allergic disease known as the alpha-Gal syndrome (AGS). Tick bites induce in humans high levels of IgE antibodies against the carbohydrate Galα1-3Galβ1-(3)4GlcNAc-R (α-Gal) present on tick salivary glycoproteins and tissues of non-catarrhine mammals, leading to the AGS in some individuals. This immune response evolved as a conflict and cooperation between ticks and human hosts including their gut microbiota. Read More

J Travel Med 2019 Apr 1. Epub 2019 Apr 1.

Travel Medicine & Tropical Diseases Clinic, Division of Infectious Diseases, Rambam Medical Center, Haifa, Israel.

Background:: Immediate and long-term recall of a pretravel consultation are suboptimal. We aimed to assess the role of online consultation for travelers.

Methods:: We randomized travelers into two study groups. Read More

Pan Afr Med J 2018 10;31:21. Epub 2018 Sep 10.

Nigeria Field Epidemiology and Laboratory Training Program, Abuja, Nigeria.

Introduction: Rabies is a fatal neglected zoonosis killing 55,000 people worldwide annually. It is endemic in Nigeria with 10,000 people exposed annually through dog-bites. To inform adequate intervention due to the rise in reported dog-bite cases, we assessed knowledge, attitudes and practices (KAP). Read More

Am J Trop Med Hyg 2019 Mar 25. Epub 2019 Mar 25.

Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland.

We evaluated differences in pretravel care, exposures, and illnesses among pediatric and adult travelers, using a prospective, observational cohort. Eighty-one pediatric travelers were matched 1:1 with adult military dependents by travel region, destination's malaria risk, and travel duration. Pediatric travelers were more likely to have coverage for hepatitis A and B (90% versus 67% of adults; 85% versus 44%), visit friends and relatives (36% versus 16%), report mosquito bites (69% versus 44%), and have close contact with wild or domesticated animals (40% versus 20%) than adults ( < 0. Read More

Parasit Vectors 2019 Mar 25;12(1):143. Epub 2019 Mar 25.

Department of Disease Control, London School of Hygiene & Tropical Medicine, London, UK.

Background: The biting behaviour and dispersal of insect vectors in the field underlies the transmission of many diseases. Here, a novel collection methodology coupled with the molecular analysis of blood-meal sources and digestion rates is introduced with the aim of aiding the understanding of two critical and relatively understudied mosquito behaviours: plasticity in blood-host choice and vector dispersal.

Results: A collection strategy utilising a transect of mosquito traps placed at 50 m intervals allowed the collection of blood-fed Anopheles coluzzii from a malaria-endemic village of southern Ghana where human host availability ranged from zero (a cattle pen), increasing until humans were the dominant host choice (the middle of the village). Read More

Parasit Vectors 2019 Mar 26;12(1):128. Epub 2019 Mar 26.

Global Health and Tropical Medicine (GHMT), Instituto de Higiene e Medicina Tropical (IHMT), Universidade Nova de Lisboa (UNL), Lisboa, Portugal.

Background: Zoonotic leishmaniosis, caused by the protozoan Leishmania infantum, is a public and animal health problem in Asia, Central and South America, the Middle East and the Mediterranean Basin. Several phlebotomine sand fly species from the subgenus Larroussius are vectors of L. infantum. Read More

Parasit Vectors 2019 Mar 21;12(1):132. Epub 2019 Mar 21.

Université de Toulouse, ENVT, Small Animal Hospital, Dermatology Service, 23, Chemin des Capelles, 31076, Toulouse cedex3, France.

Background: A prospective clinical study evaluated the tolerance and the efficacy of a combination of imidacloprid (10%) and permethrin (50%) (ADVANTIX: Bayer HC AH, France) applied topically as a spot-on, for the treatment of natural canine fly dermatitis due to Stomxys calcitrans. The study was an open-label controlled study and one-month follow-up.

Methods: Fifteen dogs, from the same animal kennel, with active pinnal lesions of fly dermatitis, received a single application of the solution on the cranium and the base of the ears on Day 0 (D0). Read More

Rev Soc Bras Med Trop 2019 Mar 18;52:e20180195. Epub 2019 Mar 18.

Laboratório de Herpetologia, Centro Multidisciplinar, Campus Floresta, Universidade Federal do Acre, Cruzeiro do Sul, AC, Brasil.

Introduction: We present here the risk from snakebites because of palm extractivism in western Amazonia.

Methods: The data were extracted from a cross-sectional sample study, from January 2016 to April 2018, at the Juruá Regional Hospital of Cruzeiro do Sul (Acre).

Results: There were 14 Bothrops incidents involving males, most of them occurring during the harvesting of "açaí" (Euterpe precatoria). Read More

Cureus 2019 Jan 8;11(1):e3845. Epub 2019 Jan 8.

Emergency Medicine, Charleston Area Medical Center, Charleston, USA.

Acute compartment syndrome (ACS) of the hand is uncommon, especially secondary to exotic animal bites. In this case, we describe a patient who developed ACS of the hand after being bitten by her pet, an African grey parrot. The patient required emergent fasciotomy that resulted in symptom improvement. Read More

Malar J 2019 Mar 18;18(1):83. Epub 2019 Mar 18.

Environmental Health and Ecological Sciences Department, Ifakara Health Institute, Off Mlabani Passage, P.O. Box 53, Ifakara, Tanzania.

Background: Mosquito biting rates and host preferences are crucial determinants of human exposure to vector-borne diseases and the impact of vector control measures. The human landing catch (HLC) is a gold standard method for measuring human exposure to bites, but presents risks to participants by requiring some exposure to mosquito vectors. Mosquito electrocuting traps (METs) represent an exposure-free alternative to HLCs for measuring human exposure to malaria vectors. Read More

Parasite Immunol 2019 May;41(5):e12624

Laboratory of Vaccinology and Applied Immunology, Kanazawa University School of Pharmacy, Kanazawa, Japan.

Plasmodium falciparum circumsporozoite protein (PfCSP) is the main target antigen in development of pre-erythrocytic malaria vaccines. To evaluate PfCSP vaccines in animal models, challenge by intravenous sporozoite injection is preferentially used. However, in clinical trials, vaccinated human volunteers are exposed to the bites of malaria-infected mosquitoes. Read More

Plast Reconstr Surg Glob Open 2018 Nov 5;6(11):e1820. Epub 2018 Nov 5.

Clinic of Plastic and Reconstructive Surgery, University of Padova, Padua, Italy.

Background: Ear avulsion is a rare complication of different traumas, such as car accidents, human or animal bites and stab wounds, and can result in dramatic cosmetic consequences for the patient. Ear replantation, revascularization, and reattachment are the options offering best aesthetic results. But venous outflow insufficiency is responsible for a high rate of failures. Read More

J Forensic Leg Med 2019 Apr 5;63:52-55. Epub 2019 Mar 5.

The University of Adelaide Medical School, Frome Road, Adelaide, SA, 5005, Australia; Forensic Science SA, 21 Divett Place, Adelaide, SA, 5000, Australia. Electronic address:

Clinical and pathological case files of lethal snakebites were reviewed from the XXXX, Magway, Myanmar, over a five-year period (January 2013 December 2017). A total of 2069 postmortem examinations were performed which included 84 cases of lethal snake bite (4.1%). Read More

Parasit Vectors 2019 Mar 12;12(1):90. Epub 2019 Mar 12.

Institute of Animal Hygiene and Veterinary Public Health, Faculty of Veterinary Medicine, University of Leipzig, An den Tierkliniken 1, 04103, Leipzig, Germany.

Background: Tick-borne encephalitis (TBE) virus is transmitted to humans and animals through tick bites and is thought to circulate in very strictly defined natural environments called natural foci. The most common tick serving as a vector for the TBE virus in central Europe is Ixodes ricinus; it is rarely found in other tick species and in Dermacentor reticulatus it has, so far, only been reported in Poland.

Methods: Between autumn 2016 and spring 2018 ticks were collected by the flagging method in a new TBE focus in the district of northern Saxony, Germany, outside the known risk areas as defined by the national Robert Koch Institute. Read More

Parasit Vectors 2019 Mar 12;12(1):87. Epub 2019 Mar 12.

Department of Wetland Ecology, Estación Biológica de Doñana (EBD-CSIC), C/Américo Vespucio 26, 41092, Seville, Spain.

Background: The transmission of mosquito-borne pathogens is strongly influenced by the contact rates between mosquitoes and susceptible hosts. The biting rates of mosquitoes depend on different factors including the mosquito species and host-related traits (i.e. Read More

Arch Insect Biochem Physiol 2019 Mar 11:e21544. Epub 2019 Mar 11.

Hebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, Hebei, China.

Ticks are obligate blood-sucking ectoparasites, which not only directly damage through bites but also transmit many pathogens. China has a high diversity of tick species, 125 species have been reported, including 111 hard tick and 14 soft tick species. Many of the ticks are important vectors of pathogens, resulting in zoonoses. Read More

Case Rep Infect Dis 2019 30;2019:2156269. Epub 2019 Jan 30.

Orthopedic Surgery and Traumatology, Department of Orthopedic Surgery and Traumatology, Military Hospital Mohammed V (HMIMV), BP 10100 Rabat, Morocco.

Almost 2% of all emergency admissions involve an animal bite. While horses bite humans very rarely, their bites are mostly associated with fatalities. Herein, we report the case of a 23-year old bitten by a domestic horse causing a crush injury to his fourth finger with fracture dislocation of the proximal interphalangeal joint. Read More

Trauma Case Rep 2019 Apr 21;20:100179. Epub 2019 Feb 21.

Spaarne Gasthuis, Department of Trauma Surgery, Spaarnepoort 1, 2143 TM, Hoofddorp, the Netherlands.

Introduction: Every year patients present to the emergency department due to bites, scratches and falls caused by animals. Although bite and scratch injuries have been described in literature, the exact number of patients that visit the emergency department due to all animal related injuries has never been described before.

Methods: A retrospective analysis of all emergency department visits throughout a 1-year period was performed from April 2015 until March 2016. Read More

Home Healthc Now 2019 Mar/Apr;37(2):111-115

Susan Lombardo, PhD, RN, is a Clinical Associate Professor, School of Nursing, D'Youville College, Buffalo, New York. Kendra Schmitz, MSN, RN, is a Clinical Assistant Professor, School of Nursing, D'Youville College, Buffalo, New York.

This article discusses safety issues involved when home healthcare clinicians visit the homes of patients with pets, particularly cats and dogs. Threats to the safety of home care clinicians are explored and concerns such as animal bites, animal scratches, and infection control are detailed in this article. Although it is acknowledged that pets can provide positive health benefits to owners, the focus is on the responsibility of the pet owners to secure pets when clinicians visit in order to keep the clinician and patient safe during the home visit. Read More

BMC Public Health 2019 Feb 27;19(1):237. Epub 2019 Feb 27.

Zoonosis Program, Department of Public Health, Ministry of Health, Thimphu, Bhutan.

Background: Dog bites are the main source of rabies infection and death in humans, contributing up to 99% of all cases. We conducted a contact-tracing study to evaluate the health seeking and treatment compliance behaviors of people following potential exposure to rabies in rabies endemic south Bhutan.

Methods: Using information from the rabies post exposure prophylaxis (PEP) register, animal-exposed victims who had visited five hospitals in south Bhutan between January and March 2017 were traced and further data were collected from them using a structured questionnaire. Read More

PLoS Negl Trop Dis 2019 02 21;13(2):e0007059. Epub 2019 Feb 21.

Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom.

Rev Bras Parasitol Vet 2019 Jan-Mar;28(1):134-139. Epub 2019 Feb 14.

Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo - FMVZ-USP, São Paulo, SP, Brasil.

Ornithonyssus bursa, known as the "tropical fowl mite", is a hematophagous mite of domestic and wild birds, occasionally biting humans. Infestation on humans occurs mainly when the abandoned nests are close to homes, or by manipulation of infested birds by humans. In Brazil, this species occurs in the south and southeast of the country. Read More

PLoS One 2019 19;14(2):e0211781. Epub 2019 Feb 19.

Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging infectious diseases, Pasteur Institute of Iran, Tehran, Iran.

Background: Q fever is a zoonotic disease of great public health importance in Iran. This disease is presented with high phase I antibody development in chronic and high phase II antibody in the acute form of illness. This study was conducted to evaluate the seroprevalence of Q fever among high-risk occupations in the Ilam province in Western Iran. Read More

Germs 2018 Dec 3;8(4):214-217. Epub 2018 Dec 3.

PhD, Laboratory of Clinical Microbiology and Molecular Microbiology, School of Medicine, University of Crete, 70013 Heraklion, Crete, Greece.

Introduction: Human pasteurellosis is a severe human infection that accounts for 20-30 human deaths annually worldwide. Mucous secretions derived from pets comprise the primary source of infection, which are transmitted through animal scratches or bites.

Case Report: We describe a case of wound infection in an immunocompetent adult with a decubitus ulcer of the lower extremity. Read More

Trop Med Int Health 2019 Feb 16. Epub 2019 Feb 16.

Heidelberg Institute of Global Health, University of Heidelberg, Germany.

Objective: To assesses what is known and identify knowledge gaps for Zika virus (ZIKV) transmission patterns.

Methods: Meta-review searching the databases BioSys; Cochrane Infectious Diseases Group Specialised Register and Cochrane Central Register of Controlled Trials; EMBASE; Google Scholar; LILACS; MEDLINE (PubMed); Web of Science; and WHOLIS with the term 'ZIKA'. Systematic reviews and reviews specifying the search methods and describing potential modes of transmission were eligible for analysis. Read More

PLoS Negl Trop Dis 2019 02 15;13(2):e0007171. Epub 2019 Feb 15.

Department of Renal Medicine, Royal Adelaide Hospital, Adelaide, Australia.

Introduction: Every year millions of people in developing countries suffer from snakebite, causing a large number of deaths and long term complications. Prevention and appropriate first aid could reduce the incidence and improve the health outcomes for those who suffer bites. However, many communities where snakebite is a major issue suffer from a lack of information about prevention and first aid measures that a family or community member could take to prevent severe envenoming, complications and poor outcomes. Read More

Am Surg 2019 Jan;85(1):64-70

The decision to introduce canines (K9s) to a law enforcement (LE) agency does not typically involve the evaluation of the fiscal or clinical impact on local hospitals. This study compared injury, cost, and care associated with K9s to a common nonlethal force method, the Thomas A Swift Electrical Rifle (TASER), to highlight the cost and resources required to treat both patient types. Patients treated for LE-related K9 and TASER injuries at a Level I community-based trauma center (2011-2016) were evaluated for level of care required (, surgeon/specialist), clinical interventions, proxy medical costs, and length of stay (LOS). Read More

PLoS Negl Trop Dis 2019 02 12;13(2):e0007116. Epub 2019 Feb 12.

Department of Entomology and Nematology, University of California, Davis, Davis, California, United States of America.

Background: Transmission of dengue virus (DENV) from humans to mosquitoes represents a critical component of dengue epidemiology. Examinations of this process have generally been hampered by a lack of methods that adequately represent natural acquisition of DENV by mosquitoes from humans. In this study, we assessed artificial and natural blood feeding methods based on rates of DENV infection and dissemination within mosquitoes for use in a field-based epidemiological cohort study in Iquitos, Peru. Read More

Rev Sci Tech 2018 Aug;37(2):439-449

Rabies is an acute and progressive encephalitis caused by lyssaviruses (family Rhabdoviridae, order Mononegavirales). Approximately 99% of the estimated 59,000 annual human rabies deaths in Africa and Asia are attributed to dog bites and are preventable through parenteral dog vaccination. In addition to dog rabies, the rabies virus also circulates in wildlife carnivores in southern Africa and virus exchange occurs readily across species barriers. Read More

Rev Sci Tech 2018 Aug;37(2):529-542

The Indian subcontinent comprises Afghanistan, Bangladesh, Bhutan, India, Nepal, the Maldives, Myanmar, Pakistan and Sri Lanka. In all of these countries, except the Maldives, rabies is endemic. An estimated 59,000 people die from rabies each year; 45% of these deaths occur on the Indian subcontinent and approximately 33% take place in India. Read More

Rev Sci Tech 2018 Aug;37(2):569-580

Rabies is an acute neurological infection of humans and animals, caused by rabies virus and usually transmitted by animal bites. After an incubation period usually lasting weeks or longer, a variety of prodromal symptoms may occur. Encephalitic rabies (80% of cases) is associated with episodes of generalised arousal or hyperexcitability and hydrophobia, in which spasms involve the contraction of inspiratory muscles with swallowing. Read More

Rev Sci Tech 2018 Aug;37(2):629-647

Rabies is entirely preventable. All deaths are the result of failed prophylaxis. Rabies encephalomyelitis has never been reported in anyone who received both pre-exposure vaccination and a post-exposure booster. Read More

PLoS Negl Trop Dis 2019 02 11;13(2):e0007090. Epub 2019 Feb 11.

Global Community Health and Behavioral Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States of America.

As part of a study to investigate drivers of dengue virus (DENV) transmission dynamics, this qualitative study explored whether DENV-infected residents of Iquitos, Peru, considered it acceptable (1) to participate in direct mosquito feeding experiments (lab-reared Aedes aegypti mosquitoes fed directly on human volunteers) and (2) to provide blood meals indirectly (Ae. aegypti fed on blood drawn from participants by venipuncture). Twelve focus group discussions (FGDs; 94 participants: 82 females and 12 males) were conducted in January 2014 to explore six themes: (1) concerns and preferences regarding direct mosquito feeds and blood draws, (2) comprehension of and misconceptions about study procedures, (3) motivating factors for participation, (4) acceptability of children's participation, (5) willingness to provide multiple samples over several days, and (6) preference for direct feedings in homes versus the study laboratory. Read More

Rev Epidemiol Sante Publique 2019 Apr 8;67(2):92-97. Epub 2019 Feb 8.

UFR Sciences médicales d'Abidjan, université Félix Houphouët Boigny de Cocody, Abidjan, Cote d'Ivoire; Institut national d'hygiène publique (Inhp), Cote d'Ivoire.

Aim: Human rabies is a major public health problem in many African countries, including Ivory Coast. The objective of this study was to evaluate the influence of human rabies knowledge on compliance with post-exposure prophylaxis.

Materials And Methods: We conducted a descriptive and analytical cross-sectional study from September 2014 to May 2015 at the Abidjan Rabid Center, Treichville. Read More

J Emerg Med 2019 02;56(2):230-231

University of California San Diego School of Medicine, San Diego, California.

J Emerg Med 2019 02;56(2):229-230

Emergency Department, Grand Strand Regional Medical Center, Myrtle Beach, South Carolina.

Wilderness Environ Med 2019 Mar 6;30(1):79-85. Epub 2019 Feb 6.

National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.

This case report documents envenomation by an arboreal white-lipped green pit viper (Trimeresurus albolabris), a species found in South and Southeast Asia that causes the majority of venomous snakebites among Southeast Asian pit vipers. Clinical features vary from asymptomatic to serious coagulopathy that may progress into life-threatening or fatal hemorrhage. The proven life-threatening cases described in published literature, however, are sparse. Read More

J Enzyme Inhib Med Chem 2019 Dec;34(1):310-321

a Immunochemistry Laboratory , Butantan Institute , São Paulo , SP , Brazil.

Loxosceles spiders' venoms consist of a mixture of proteins, including the sphingomyelinases D (SMases D), which are the main toxic components responsible for local and systemic effects in human envenomation. Herein, based on the structural information of SMase D from Loxosceles laeta spider venom and virtual docking-based screening approach, three benzene sulphonate compounds (named 1, 5 and 6) were identified as potential Loxosceles SMase D inhibitors. All compounds inhibited the hydrolysis of the sphingomyelin substrate by both recombinant and native SMases D. Read More

An Bras Dermatol 2019 Jan-Feb;94(1):122-123

Postgraduate Program in Infectious Diseases, Health Science Center, Universidade Federal do Espírito Santo, Vitória (ES), Brazil.

Ann Parasitol 2018;64(4):309-315

Department of Epizootiology and Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Sciences, ul. Głęboka 30, 20-612 Lublin, Poland

Bartonellosis is a disease caused by Bartonella spp. microorganisms which belong to the Rickettsiales order. This disease is a zoonosis, B. Read More

Vet Ophthalmol 2019 Feb 4. Epub 2019 Feb 4.

Department of Pathological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin.

Purpose: To describe the clinical and histopathologic features secondary to ocular and periocular snakebites in dogs requiring enucleation.

Methods: Retrospective review of patients with recorded snakebite envenomation from the archives of the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) and Texas A&M Veterinary Medical Teaching Hospital (1997-2017). The cases included in this study required witnessed snakebites to the dog by the owner, clinical signs supportive of periocular or ocular envenomation, and/or histopathologic lesions compatible with snakebites. Read More