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    Synergy between dinotefuran and fipronil against the cat flea (Ctenocephalides felis): improved onset of action and residual speed of kill in adult cats.
    Parasit Vectors 2017 Jul 19;10(1):341. Epub 2017 Jul 19.
    Ceva Santé Animale, 10 avenue de la Ballastière, 33500, Libourne, France.
    Background: The cat flea, Ctenocephalides felis felis (C. felis), is a cosmopolitan hematophagous ectoparasite, and is considered to be the most prevalent flea species in both Europe and the USA. Clinical signs frequently associated with flea bites include pruritus, dermatitis and in severe cases even pyodermatitis and alopecia. Read More

    The incidence of public sector hospitalisations due to dog bites in Australia 2001-2013.
    Aust N Z J Public Health 2017 Jul 16. Epub 2017 Jul 16.
    Advanced Animal Dentistry, Queensland.
    Objective: To estimate the incidence of dog bite-related injuries requiring public sector hospitalisation in Australia during the period 2001-13.

    Methods: Summary data on public sector hospitalisations due to dog bite-related injuries with an ICD 10-AM W54.0 coding were sourced from the Australian Institute of Health and Welfare for the study period 2001-2013. Read More

    Dog-bites, rabies and One Health: Towards improved coordination in research, policy and practice.
    Soc Sci Med 2017 Aug 28;187:126-133. Epub 2017 Jun 28.
    Centre for Values, Ethics and the Law in Medicine, School of Public Health, University of Sydney, Canada.
    Dog-bites and rabies are neglected problems worldwide, notwithstanding recent efforts to raise awareness and to consolidate preventive action. As problems, dog-bites and rabies are entangled with one another, and both align with the concept of One Health. This concept emphasizes interdependence between humans and non-human species in complex socio-ecological systems. Read More

    A Clinical Approach to Animal Bites with an Avulsion Flap: A Case Report.
    Perm J 2017 ;21
    Physician Assistant in the Emergency Department at the San Diego Medical Center in CA.
    Introduction: Animal bites are a common reason for visits to the Emergency Department in the US and worldwide. There are many different approaches to managing these wounds.

    Case Presentation: We present a case of a 90-year-old white woman who sustained a large dog bite to her hand, over the dorsal aspect of the first metacarpal. Read More

    Bites from the same dog, different outcomes for two patients: a case report.
    Infect Dis Poverty 2017 Jul 5;6(1):107. Epub 2017 Jul 5.
    Henan Center for Disease Control and Prevention, Zhengzhou, China.
    Background: Rabies is a serious reemerging zoonosis in China. At present human rabies cases are primarily diagnosed based on clinical presentation.

    Case Presentation: In August 2012, a woman and her son were attacked by a stray dog in Henan, China. Read More

    Incidence and mortality due to snakebite in the Americas.
    PLoS Negl Trop Dis 2017 Jun 21;11(6):e0005662. Epub 2017 Jun 21.
    CERPAGE, Faculté des Sciences de la Santé, Université d'Abomey-Calavi, Cotonou, Bénin.
    Background: Better knowledge of the epidemiological characteristics of snakebites could help to take measures to improve their management. The incidence and mortality of snakebites in the Americas are most often estimated from medical and scientific literature, which generally lack precision and representativeness.

    Methodology/principal Findings: Authors used the notifications of snakebites treated in health centers collected by the Ministries of Health of the American countries to estimate their incidence and mortality. Read More

    Epidemiology of Animal Bites and Factors Associated With Delays in Initiating Post-exposure Prophylaxis for Rabies Prevention Among Animal Bite Cases: A Population-based Study.
    J Prev Med Public Health 2017 ;50(3):210-216
    Department of Health Economic, School of Nursing and Midwifery, Maragheh University of Medical Sciences, Maragheh, Iran.
    Objectives: One way to prevent deaths due to rabies is the timely utilization of post-exposure prophylaxis (PEP). Therefore, in addition to an understanding of the epidemiological distribution of animal bites, it is necessary to explore the factors leading to delays in PEP initiation.

    Methods: This cross-sectional study was conducted in Iran in 2011, and included 7097 cases of animal bites recorded at the Rabies Treatment Center of the Shiraz University of Medical Sciences using the census method. Read More

    Animal, Microbial, and Fungal Borne Skin Pathology in the Mountain Wilderness: A Review.
    Wilderness Environ Med 2017 Jun;28(2):127-138
    School of Medicine, University of Colorado, Aurora, Colorado (Drs Brandenburg, Califf, Manly, and Levandowski).
    Mountains are home to numerous organisms known to cause skin disease. Bites, stings, poisons, chemicals, toxins, trauma, and infections all contribute to this end. Numerous plants, animals, fungi, bacteria, viruses, and protozoa are responsible. Read More

    Novel Areas for Prevention and Control of Canine Leishmaniosis.
    Trends Parasitol 2017 Jun 7. Epub 2017 Jun 7.
    Department of Veterinary Medicine and Food Production, University of Naples Federico II, Via Delpino 1, Naples 80137, Italy.
    There have been multiple recent advances regarding tools for the control and prevention of canine leishmaniosis (CanL), including new preventative vaccines. In this review, these advances are evaluated based on control targets, including vector and parasite. Leishvet recommendations are provided for control practices based on the dog's risk of infection. Read More

    Domestic Predation of an Elder: A Fatal Dog Attack Case.
    J Forensic Sci 2017 Jun 9. Epub 2017 Jun 9.
    Service de Médecine Légale, CHU Lille, F-59000, Lille, France.
    We present the case of a 91-year-old woman lived alone at her home with two domestic dogs, that is,, a Labrador Retriever and a Staffordshire Bull Terrier and found dead. The investigation of the scene revealed that the Bull Terrier's jawbone and chest were covered with blood. The autopsy revealed multiple, histologically confirmed, life-threatening skin and bone lacerations without scavenging marks. Read More

    Dog rabies data reported to multinational organizations from Southern and Eastern African countries.
    BMC Res Notes 2017 Jun 8;10(1):199. Epub 2017 Jun 8.
    Business Economics Group, Wageningen University, Hollandseweg 1, 6706KN, Wageningen, The Netherlands.
    Objective: Rabies is one of the viral diseases with the highest case fatality rate in humans. The main transmission route to humans is through bites, especially of infected dogs. Decisions on the allocation of resources to control and reduce the socio-economic impacts of rabies require reliable data. Read More

    Acute kidney injury complicating bee stings - a review.
    Rev Inst Med Trop Sao Paulo 2017 Jun 1;59:e25. Epub 2017 Jun 1.
    Universidade Federal do Ceará, Faculdade de Medicina, Departamento de Medicina Clínica, Fortaleza, Ceará, Brazil.
    Bee stings can cause severe reactions and have caused many victims in the last years. Allergic reactions can be triggered by a single sting and the greater the number of stings, the worse the prognosis. The poisoning effects can be systemic and can eventually cause death. Read More

    Going beyond personal protection against mosquito bites to eliminate malaria transmission: population suppression of malaria vectors that exploit both human and animal blood.
    BMJ Glob Health 2017 Mar 26;2(2):e000198. Epub 2017 Apr 26.
    Oxford Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.
    Protecting individuals and households against mosquito bites with long-lasting insecticidal nets (LLINs) or indoor residual spraying (IRS) can suppress entire populations of unusually efficient malaria vector species that predominantly feed indoors on humans. Mosquitoes which usually feed on animals are less reliant on human blood, so they are far less vulnerable to population suppression effects of such human-targeted insecticidal measures. Fortunately, the dozens of mosquito species which primarily feed on animals are also relatively inefficient vectors of malaria, so personal protection against mosquito bites may be sufficient to eliminate transmission. Read More

    A fatal case of hypothermia caused by dog bites.
    Med Sci Law 2017 Jul 6;57(3):130-133. Epub 2017 Jun 6.
    1 Department of Forensic Pathology, School of Forensic Medicine, China Medical University, Shenyang, PR China.
    Death from hypothermia usually *We presented a fatal case of hypothermia after being bitten by dog in this article. occurs among people exposed to cold and humid environmental conditions when they are homeless, aged, suffering from natural or psychiatric diseases and drug or alcohol intoxication. A normal healthy person dying from hypothermia due to dog bites is unusual and rare. Read More

    Absolute venomics: Absolute quantification of intact venom proteins through elemental mass spectrometry.
    J Proteomics 2017 Jul 2;164:33-42. Epub 2017 Jun 2.
    Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Científicas (CSIC), Jaume Roig 11, 46010 Valencia, Spain. Electronic address:
    We report the application of a hybrid element and molecular MS configuration for the parallel absolute quantification of μHPLC-separated intact sulfur-containing venom proteins, via ICP triple quadrupole MS and (32)S/(34)S isotope dilution analysis, and identification by ESI-QToF-MS of the toxins of the medically important African black-necked spitting cobra, Naja nigricollis (Tanzania); New Guinea small-eyed snake, Micropechis ikaheka; and Papuan black snake, Pseudechis papuanus. The main advantage of this approach is that only one generic sulfur-containing standard is required to quantify each and all intact Cys- and/or Met-containing toxins of the venom proteome. The results of absolute quantification are in reasonably good agreement with previously reported relative quantification of the most abundant protein families. Read More

    Mosquito co-infection with Zika and chikungunya virus allows simultaneous transmission without affecting vector competence of Aedes aegypti.
    PLoS Negl Trop Dis 2017 Jun 1;11(6):e0005654. Epub 2017 Jun 1.
    Laboratory of Virology, Wageningen University & Research, Wageningen, The Netherlands.
    Background: Zika virus (ZIKV) and chikungunya virus (CHIKV) are highly pathogenic arthropod-borne viruses that are currently a serious health burden in the Americas, and elsewhere in the world. ZIKV and CHIKV co-circulate in the same geographical regions and are mainly transmitted by Aedes aegypti mosquitoes. There is a growing number of case reports of ZIKV and CHIKV co-infections in humans, but it is uncertain whether co-infection occurs via single or multiple mosquito bites. Read More

    Infrared thermography to diagnose and manage venomous animal bites and stings.
    Rev Soc Bras Med Trop 2017 Mar-Apr;50(2):260-264
    Divisão de Neurologia e Neurocirurgia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, SP, São Paulo, Brasil.
    Introduction: Infrared imaging (IR) is a noninvasive technique that quantifies body surface temperature, producing a digital color image. IR has been used to study diseases in which skin temperature can reflect the presence of inflammation.

    Methods: This was an observational pilot study of eight patients envenomed by snakes, spiders, and scorpions. Read More

    Bilateral Testicular Loss due to Dog Bite in a Child.
    APSP J Case Rep 2017 May-Jun;8(3):20. Epub 2017 May 1.
    Department of Urology, Kobe Children's Hospital, Kobe, Japan.
    Although animal bites are common, genital trauma caused by animal bites is rare. Here we report a case of bilateral testicular loss in an infant due to a dog bite. The patient was bitten by a friend's dog while his mother was intoxicated and, therefore, did not receive immediate medical attention. Read More

    Soft Tissue Management in Facial Trauma.
    Semin Plast Surg 2017 May;31(2):73-79
    Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.
    The management of soft tissue injury after facial trauma poses unique challenges to the plastic surgeon, given the specialized nature of facial tissue and the aesthetic importance of the face. The general principles of trauma management and wound care are applied in all cases. The management of severe injuries to the face is discussed in relation to the location and the mechanism of injury. Read More

    Ethnopharmacological uses, phytochemistry, biological activities, and therapeutic applications of Clinacanthus nutans (Burm. f.) Lindau: A comprehensive review.
    J Ethnopharmacol 2017 Jul 8;206:245-266. Epub 2017 May 8.
    Pharmacy, School of Medicine, University of Tasmania, 7001 Hobart, Tasmania, Australia.
    Ethnopharmacological Relevance: Clinacanthus nutans (Burm. f.) Lindau, a widely used medicinal plant, is extensively grown in tropical Asia and Southeast Asian countries. Read More

    Human fatalities caused by animal attacks: A six-year autopsy study.
    Med Leg J 2017 Jan 1:25817217707166. Epub 2017 Jan 1.
    1 Dept. of Forensic Medicine and Toxicology, Indira Gandhi Govt. Medical College & Hospital, Nagpur, India.
    Deaths caused by animal attacks in urban as well as rural areas are rising. With dwindling forest cover and with more interaction of animals with humans in day-to-day life, we need to understand the reasons, manner and causes of these fatal events. We studied 151 cases of fatal animal/human conflicts and in particular, the manner and mechanism of causation of injuries with respect to different types of animals. Read More

    Laboratory Animal Bite Anaphylaxis-A National Survey: Part 1: Case Series and Review of the Literature.
    J Occup Environ Med 2017 Apr 20. Epub 2017 Apr 20.
    Division of Occupational and Environmental Medicine, Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina.
    Objective: This study documents previously unreported cases of laboratory animal bite anaphylaxis in animal laboratory facilities in the United States.

    Methods: An online survey was e-mailed to designated institutional officials at laboratory animal facilities identified by the National Institutes of Health Office of Laboratory Animal Welfare.

    Results: One hundred ninety eight organizations responded and 15 organizations indicated that workers had experienced anaphylaxis following an animal bite. Read More

    Efficacy and user acceptability of transfluthrin-treated sisal and hessian decorations for protecting against mosquito bites in outdoor bars.
    Parasit Vectors 2017 Apr 20;10(1):197. Epub 2017 Apr 20.
    Environmental Health and Ecological Sciences Department, Ifakara Health Institute, Off Mlabani Passage, Ifakara, P.O Box 53, Morogoro, United Republic of Tanzania.
    Background: A number of mosquito vectors bite and rest outdoors, which contributes to sustained residual malaria transmission in endemic areas. Spatial repellents are thought to create a protective "bubble" within which mosquito bites are reduced and may be ideal for outdoor use. This study builds on previous studies that proved efficacy of transfluthrin-treated hessian strips against outdoor biting mosquitoes. Read More

    Thromboelastography Utilization in Delayed Recurrent Coagulopathy after Severe Eastern Diamondback Rattlesnake Envenomation.
    Am Surg 2017 Apr;83(4):332-336
    Venomous snakebites are fairly common in the United States and can present with a wide range of symptoms. A 48-year-old man presented after Eastern Diamondback rattlesnake envenomation. His hospital course was complicated by right leg compartment syndrome and delayed recurrent coagulopathy, requiring multiple doses of Crotalidae Polyvalent Immune Fab (CroFab) antivenom and transfusions. Read More

    Tick-host conflict: immunoglobulin E antibodies to tick proteins in patients with anaphylaxis to tick bite.
    Oncotarget 2017 Mar;8(13):20630-20644
    SaBio, Instituto de Investigación de Recursos Cinegéticos, IREC-CSIC-UCLM-JCCM, Ciudad Real, Spain.
    Tick-borne infectious diseases and allergies are a growing problem worldwide. Tick bite allergy has been associated with the direct effect of immunoglobulin E (IgE) response to tick salivary antigens, or secondary to the induction of allergy to red meat consumption through IgE antibodies against the carbohydrate α-Gal (Gal α 1-3Gal β 1-(3)4GlcNAc-R). However, despite the growing burden of this pathology, the proteins associated with anaphylaxis to tick bite have not been characterized. Read More

    Defining the complex phenotype of severe systemic loxoscelism using a large electronic health record cohort.
    PLoS One 2017 19;12(4):e0174941. Epub 2017 Apr 19.
    Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States of America.
    Objective: Systemic loxoscelism is a rare illness resulting from the bite of the recluse spider and, in its most severe form, can lead to widespread hemolysis, coagulopathy, and death. We aim to describe the clinical features and outcomes of the largest known cohort of individuals with moderate to severe loxoscelism.

    Methods: We performed a retrospective, cross sectional study from January 1, 1995, to December 31, 2015, at a tertiary-care academic medical center, to determine individuals with clinical records consistent with moderate to severe loxoscelism. Read More

    Community-based survey during rabies outbreaks in Rangjung town, Trashigang, eastern Bhutan, 2016.
    BMC Infect Dis 2017 Apr 17;17(1):281. Epub 2017 Apr 17.
    Regional Livestock Development Centre, Department of Livestock, Khangma, Trashigang, Bhutan.
    Background: Rabies is a highly fatal disease transmitted through the bite of a rabid animal. Human deaths can be prevented by prompt administering of rabies vaccine and rabies immunoglobulin following the exposure. An assessment of community knowledge, awareness and practices on rabies is important during outbreak to understand their preparedness and target educational messages and response activities by the rapid response team. Read More

    Arthropod Envenomation in North America.
    Emerg Med Clin North Am 2017 May;35(2):355-375
    Section of Emergency Medicine, University of Chicago, Chicago, IL, USA.
    Arthropods (phylum Arthopoda) account for a higher percentage of morbidity and mortality to humans than do mammalian bites, snake bites, or marine envenomation. They are ubiquitous in domestic dwellings, caves, and campsites and in wilderness settings such as deserts, forests, and lakes. Although arthropods are most intrusive during warmer months, many are active throughout the winter, particularly indoors. Read More

    North American Snake Envenomation.
    Emerg Med Clin North Am 2017 May;35(2):339-354
    Division of Medical Toxicology, Department of Emergency Medicine, UC San Diego Health, 200 West Arbor Drive # 8676, San Diego, CA 92103, USA.
    Native US snakes that produce clinically significant envenomation can be divided into 2 groups, crotalids and elapids. The crotalids include rattlesnakes, cottonmouths, and copperheads. Crotalid envenomation can result in significant local tissue damage as well as thrombocytopenia and coagulopathy. Read More

    Mycobacterium ulcerans low infectious dose and mechanical transmission support insect bites and puncturing injuries in the spread of Buruli ulcer.
    PLoS Negl Trop Dis 2017 Apr 14;11(4):e0005553. Epub 2017 Apr 14.
    Department of Microbiology and Immunology, at the Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia.
    Addressing the transmission enigma of the neglected disease Buruli ulcer (BU) is a World Health Organization priority. In Australia, we have observed an association between mosquitoes harboring the causative agent, Mycobacterium ulcerans, and BU. Here we tested a contaminated skin model of BU transmission by dipping the tails from healthy mice in cultures of the causative agent, Mycobacterium ulcerans. Read More

    Zika Virus: Common Questions and Answers.
    Am Fam Physician 2017 Apr;95(8):507-513
    Centers for Disease Control and Prevention, Atlanta, GA, USA.
    Since local mosquito-borne transmission of Zika virus was first reported in Brazil in early 2015, the virus has spread rapidly, with active transmission reported in at least 61 countries and territories worldwide, including the United States. Zika virus infection during pregnancy is a cause of microcephaly and other severe brain anomalies. The virus is transmitted primarily through the bite of an infected Aedes mosquito, but other routes of transmission include sexual, mother-to-fetus during pregnancy, mother-to-infant at delivery, laboratory exposure, and, possibly, transfusion of blood products. Read More

    Bacteremia caused by Bergeyella zoohelcum in an infective endocarditis patient: case report and review of literature.
    BMC Infect Dis 2017 Apr 12;17(1):271. Epub 2017 Apr 12.
    Department of Laboratory Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China.
    Background: Bergeyella zoohelcum is an aerobic, Gram-negative bacterium that is frequently isolated from the upper respiratory tract of dogs, cats and other mammals. Clinically, B. zoohelcum has been reported causing cellulitis, tenosynovitis, leg abscess and septicemia, which is closely connected with animal bites. Read More

    Preparation and neutralization efficacy of IgY antibodies raised against Deinagkistrodon acutus venom.
    J Venom Anim Toxins Incl Trop Dis 2017 4;23:22. Epub 2017 Apr 4.
    Animal Toxin Group, Chongqing Key Laboratory of Animal Biology, Chongqing Engineering Research Center of Bioactive Substances, Engineering Research Center of Active Substances and Biotechnology, Ministry of Education, College of Life Science, Chongqing, 401331 China.
    Background: The five-paced pit viper (Deinagkistrodon acutus), endemic to China and northern Vietnam, is responsible for most snakebites in the Chinese territory. Antivenom produced from horses is the main treatment for snakebites, but it may cause numerous clinical side effects and have other disadvantages involved in their production such as the welfare of animals. The present study was conducted aiming to develop an alternative antibody (IgY) from the egg yolk of leghorn chickens immunized with snake venom. Read More

    Examining evidence on dog bite injuries and their management in children.
    Nurs Child Young People 2017 Apr;29(3):35-39
    Birmingham Children's Hospital NHS Foundation Trust, Birmingham, England.
    Dog bites are common injuries in children. The effects of such injuries can be devastating for the children concerned and their families. It is therefore important to provide holistic care and to consider psychological well-being as well as physical recovery. Read More

    A low technology emanator treated with the volatile pyrethroid transfluthrin confers long term protection against outdoor biting vectors of lymphatic filariasis, arboviruses and malaria.
    PLoS Negl Trop Dis 2017 Apr 7;11(4):e0005455. Epub 2017 Apr 7.
    Ifakara Health Institute, Environmental Health and Ecological Sciences Thematic Group, Coordination Office, Dar es Salaam, United Republic of Tanzania.
    Background: The vapor phase of the volatile pyrethroid transfluthrin incapacitates mosquitoes and prevents them from feeding. Although existing emanator products for delivering volatile pyrethroids protect against outdoor mosquito bites, they are too short-lived to be practical or affordable for routine use in low-income settings. New transfluthrin emanators, comprised simply of treated hessian fabric strips, have recently proven highly protective against outdoor-biting vectors of lymphatic filariasis, arboviruses and malaria, but their full protective lifespan, minimum dose requirements, and range of protection have not previously been assessed. Read More

    On gonads and gadflies: the estrus angle.
    J Endocrinol 2017 Jun 6;233(3):C1-C8. Epub 2017 Apr 6.
    Medical Research Council Centre for Reproductive HealthUniversity of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom
    The first sex steroid to be crystallized was the vertebrate ovarian hormone, estrone - a less potent metabolite of 17β-estradiol, which in mammals stimulates the female urge to mate (estrus). The gadfly (Greek oistros) lent its name to the process of estrus, as an insect that bites and torments in classical Greek mythology. With the purification and crystallization of a moult-inducing steroid (ecdysone) from insects, an interesting parallel emerged between mating and moulting in lower mammals and arthropods. Read More

    Successful strategies implemented towards the elimination of canine rabies in the Western Hemisphere.
    Antiviral Res 2017 Jul 4;143:1-12. Epub 2017 Apr 4.
    Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, Atlanta, 30329 GA, USA.
    Almost all cases of human rabies result from dog bites, making the elimination of canine rabies a global priority. During recent decades, many countries in the Western Hemisphere have carried out large-scale dog vaccination campaigns, controlled their free-ranging dog populations and enforced legislation for responsible pet ownership. This article reviews progress in eliminating canine rabies from the Western Hemisphere. Read More

    Unusual Aetiology of Pasteurella canis Biovar 2 Causing Dacryocystitis in HIV Patient: A Case Report and Review of Literature.
    J Clin Diagn Res 2017 Feb 1;11(2):DD01-DD03. Epub 2017 Feb 1.
    Senior Resident, Department of Microbiology, All India Institute of Medical Sciences , Raipur, Chhattisgarh, India .
    Pasteurella species are zoonotic bacterial pathogens implicated very infrequently in various human infections following animal bites or licks usually of dogs and cats. This case report described a rare clinical presentation of dacryocystitis caused by P.canis in a Human Immunodeficiency Virus (HIV) positive young male patient involved in caring of cattle. Read More

    Animal Bite Injuries in Children: Review of Literature and Case Series.
    Int J Clin Pediatr Dent 2017 Jan-Mar;10(1):67-72. Epub 2017 Feb 27.
    Assistant Professor,Department of Oral and Maxillofacial Surgery, Postgraduate Institute of Dental Sciences, Rohtak, Haryana, India.
    Introduction: Maxillofacial region in children is particularly vulnerable to animal bite injuries. These injuries may range from insignificant scratches to life-threatening neck and facial injuries. Children are the common victims, particularly of dog bites. Read More

    In Vitro Activity of Pexiganan and 10 Comparator Antimicrobials against 234 Isolates, Including 93 Pasteurella Species and 50 Anaerobic Bacterial Isolates Recovered from Animal Bite Wounds.
    Antimicrob Agents Chemother 2017 Jun 24;61(6). Epub 2017 May 24.
    R. M. Alden Research Laboratory, Culver City, California, USA.
    Animal bite wounds affect more than 5 million Americans annually, resulting in 300,000 emergency department visits, 10,000 hospitalizations, and an untold number of physician office visits. Various forms of topical therapy are empirically self-employed by many patients prior to seeking medical attention. Pexiganan, a 22-amino-acid synthetic cationic analogue of the peptide magainin II, acts by selectively damaging bacterial cell membranes. Read More

    Ticks and Tick Bites Presenting as "Funny Moles": A Review of Different Presentations and a Focus on Tick-borne Diseases.
    J Clin Aesthet Dermatol 2017 Mar 1;10(3):46-50. Epub 2017 Mar 1.
    Veterans Affairs Medical Center, Brooklyn, New York.
    Purpose: To describe a man with an adherent tick mimicking a melanoma, summarize the salient features of this condition, and review other cases of ticks mistaken for dermatoses. Background: Ticks are obligatory ectoparasites. Disease-causing ticks belong to two families: Ixodidae (hard ticks) and Argasidae (soft ticks). Read More

    Hot water immersion v icepacks for treating the pain of Chironex fleckeri stings: a randomised controlled trial.
    Med J Aust 2017 Apr;206(6):258-261
    Menzies School of Health, Royal Darwin Hospital, Darwin, NT.
    Objective: To investigate the effectiveness of hot water immersion for relieving the pain of major box jellyfish (Chironex fleckeri) stings.Design, interventions: Open label, randomised controlled trial comparing the effects of hot water immersion (45°C) and icepacks.Setting, participants: 42 patients with suspected C. Read More

    Repellent effect of microencapsulated essential oil in lotion formulation against mosquito bites.
    J Vector Borne Dis 2017 Jan-Mar;54(1):44-53
    Medical Entomology Unit, Institute of Medical Research, Kuala Lumpur, Malaysia.
    Background & Objectives: Many essential oils have been reported as natural sources of insect repellents; however, due to high volatility, they present low repellent effect. Formulation technique by using microencapsulation enables to control the volatility of essential oil and thereby extends the duration of repellency. In this study, the effectiveness of microencapsulated essential oils of Alpinia galanga, Citrus grandis and C. Read More

    Antivenom for European Vipera species envenoming.
    Clin Toxicol (Phila) 2017 Jul 28;55(6):557-568. Epub 2017 Mar 28.
    a Department of Pharmacology, Toxicology, and Therapeutics , University/BHF Centre for Cardiovascular Science, University of Edinburgh , Edinburgh , UK.
    Background: European viper bite is relatively uncommon but can cause serious envenoming, particularly swelling and hemorrhage spreading from limb to trunk that can cause long term disability. Systemic features are relatively mild compared to many other venomous species. Moderate-to-severe envenoming requires antivenom, which is given many hundreds of times each year across the continent. Read More

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