364,010 results match your criteria Birth Defects Research Part B-developmental And Reproductive Toxicology[Journal]


[Effects of hyperemesis gravidarum on the course of pregnancy and birth, with special attention to the risk factor of migration background].

Z Geburtshilfe Neonatol 2020 Jul 6. Epub 2020 Jul 6.

Klinik für Gynäkologie, Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Berlin.

Main Questions: In this investigation of hospitalized cases of HG and subsequent births, we examine differences between patients who have and who have not experienced migration as well as the effect of HG on perinatal outcome.

Methods: Retrospective quantitative data of hospitalized patients suffering from HG (1997-2015) was analyzed. Also analyzed was a retrospective record of perinatal data on a subgroup of patients (2002-2016), and a control group (matched pairs) based on the register of births created. Read More

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http://dx.doi.org/10.1055/a-1144-3811DOI Listing

Outcome of Very Low and Low Birth Weight Infants with Esophageal Atresia: Results of the Turkish Esophageal Atresia Registry.

Eur J Pediatr Surg 2020 Jul 6. Epub 2020 Jul 6.

Department of Pediatric Surgery, Sisli Hamidiye Etfal Education and Research Hospital, Istanbul, Turkey.

Introduction:  The data of the Turkish Esophageal Atresia Registry (TEAR) was evaluated to define the outcome of very low birth weight (VLBW) and low BW (LWB) infants with esophageal atresia (EA).

Materials And Methods:  The data registered by 24 centers between 2014 and 2018 were evaluated for demographic features, prenatal findings, associated anomalies, surgical treatment, and outcome. Patients were enrolled in three groups according to their BWs (VLBW <1,500 g), LWB = 1,500-2,500 g), and normal BW (NBW; >2,500 g). Read More

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http://dx.doi.org/10.1055/s-0040-1713663DOI Listing

Q Fever (Coxiella Burnetii).

Semin Respir Crit Care Med 2020 Aug 6;41(4):509-521. Epub 2020 Jul 6.

Department of Pneumology, Hospital Clinic of Barcelona, Barcelona, Spain.

Q fever is a zoonotic infectious disease caused by the bacterium. It is an obligate intracellular pathogen with a high infection capacity that proliferates exclusively in an acidified medium, forming a lysosome-like vacuole. It presents a peculiar phenomenon called "antigenic phase variation," produced by a modification in the complexity of the membrane lipopolysaccharides. Read More

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http://dx.doi.org/10.1055/s-0040-1710594DOI Listing

Clinical spectrum and prevalence of congenital heart disease in children in Botswana.

Cardiovasc J Afr 2020 Jun 22;31:1-5. Epub 2020 Jun 22.

Department of Paediatric and Adolescent Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana; Department of Paediatrics, Princess Marina Hospital, Gaborone, Botswana.

Background: Reliable data on congenital heart disease (CHD) from diverse settings is important both for planning health systems in each country and to elucidate possible aetiologies of CHD in different settings. There is a lack of data on the clinical spectrum and prevalence of CHD in Botswana. The aim of this study was to describe the clinical spectrum and prevalence of CHD in Botswana. Read More

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http://dx.doi.org/10.5830/CVJA-2020-021DOI Listing

Shedding light on excessive crying in babies.

Pediatr Res 2020 Jul 6. Epub 2020 Jul 6.

Division of Development and Growth, Department of Pediatrics, Obstetrics and Gynaecology, University of Geneva, Geneva, Switzerland.

Background: Excessive and inconsolable crying behavior in otherwise healthy infants (a condition called infant colic (IC)) is very distressing to parents, may lead to maternal depression, and in extreme cases, may result in shaken baby syndrome. Despite the high prevalence of this condition (20% of healthy infants), the underlying neural mechanisms of IC are still unknown.

Methods: By employing the latest magnetic resonance imaging (MRI) techniques in newborns, we prospectively investigated whether newborns' early brain responses to a sensory stimulus (smell) is associated with a subsequent crying behavior. Read More

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http://dx.doi.org/10.1038/s41390-020-1048-6DOI Listing

Fetoscopic Laser Ablation Therapy for Type II Vasa Previa.

Fetal Diagn Ther 2020 Jul 6:1-7. Epub 2020 Jul 6.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Background: In type II vasa previa, fetoscopic laser ablation has the potential to avoid prolonged hospitalization, elective prematurity, and cesarean delivery associated with traditional conservative management.

Objective: To assess the feasibility and to report perinatal outcomes of type II vasa previa patients treated via fetoscopic laser ablation.

Study Design: This is a retrospective descriptive study of all women with vasa previa treated with laser at our center between 2006 and 2019. Read More

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http://dx.doi.org/10.1159/000508044DOI Listing

Insomnia symptoms increase during pregnancy, but no increase in sleepiness - Associations with symptoms of depression and anxiety.

Sleep Med 2020 Apr 9;72:150-156. Epub 2020 Apr 9.

Department of Obstetrics and Gynecology, Turku University Hospital and University of Turku, Turku, Finland; Sleep Research Unit, Department of Physiology, University of Turku, Turku, Finland.

Objective: To evaluate alteration in insomnia and sleepiness symptoms during pregnancy and assess early pregnancy risk factors for these symptoms, especially depressive and anxiety symptoms.

Methods: A cohort of 1858 women was enrolled from the FinnBrain Birth Cohort Study. Insomnia and sleepiness symptoms were measured in early, mid- and late pregnancy with the Basic Nordic Sleep Questionnaire. Read More

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http://dx.doi.org/10.1016/j.sleep.2020.03.031DOI Listing

Neonatal outcomes in obese pregnant women who develop preeclampsia.

Pregnancy Hypertens 2020 Jun 1;21:191-196. Epub 2020 Jun 1.

Department of Obstetrics & Gynecology, Nassau University Medical Center, East Meadow, NY, USA; Department of Business Management, Brooklyn College of the City University of New York, Brooklyn, NY, USA. Electronic address:

Objective: Obesity and preeclampsia in pregnant women are each independently associated with poorer neonatal outcomes. We study obesity and preeclampsia alone and also in combination in pregnant women to determine their association with neonatal outcomes.

Study Design: This retrospective study (n = 664) compared four groups: 1) no preeclampsia/no obesity, 2) no preeclampsia/yes obesity, 3) yes preeclampsia/no obesity, and 4) yes preeclampsia/yes obesity. Read More

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http://dx.doi.org/10.1016/j.preghy.2020.05.016DOI Listing

Management factors associated with time-to-onset and fecal egg/oocyst counts of gastrointestinal parasites in heifer calves on Kenyan smallholder farms.

Vet Parasitol 2020 Jun 23;283:109174. Epub 2020 Jun 23.

Department of Biomedical Sciences, Atlantic Veterinary College, UPEI, Canada.

A prospective cohort study on zero-grazed smallholder dairy farms was conducted to determine factors associated with onset and counts of gastrointestinal parasitism in heifer calves. The researchers recruited 187 newborn heifer calves from 150 farms in Kenya. Over 16 months, farm visits every two months were used to collect rectal fecal samples and animal- and farm-level measures. Read More

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http://dx.doi.org/10.1016/j.vetpar.2020.109174DOI Listing

Utility of Neonatal Ophthalmologic Examination for Detection of Infectious Etiologies for Symmetric Intrauterine Growth Restriction.

J Pediatr 2020 Jul 3. Epub 2020 Jul 3.

Wills Eye Hospital, Philadelphia, PA; Cooper University Hospital, Camden, NJ.

Objective: To determine the utility of ophthalmologic examination as part of evaluation for infection in infants with intrauterine growth restriction (IUGR).

Study Design: This is a single-institution retrospective chart review of neonates diagnosed with symmetric IUGR or small for gestational age (SGA) who underwent complete ophthalmologic consultation to assess for intraocular findings suggestive of congenital infection. Data collected included other factors that may cause IUGR, findings of the general and ophthalmologic examination, and results of investigation for intrauterine infection. Read More

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http://dx.doi.org/10.1016/j.jpeds.2020.07.003DOI Listing

Multi and transgenerational epigenetic effects of di-(2-ethylhexyl) phthalate (DEHP) in liver.

Toxicol Appl Pharmacol 2020 Jul 3:115123. Epub 2020 Jul 3.

Department of Bioengineering. University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Biomedical Research Center in Mills Breast Cancer Institute, Carle Foundation Hospital, Urbana, IL 61801, USA; Department of Comparative Biosciences, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA; Micro and Nanotechnology Laboratory. University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Electronic address:

Di-(2-ethylhexyl) phthalate (DEHP), a ubiquitous industrial pollutant, is a known endocrine disrupter implicated in metabolic diseases. Prenatal DEHP exposure promotes epigenetic multi- and transgenerational inheritance of adult onset disease in subsequent generations (F1-F3), however, the epigenetic toxicity is less understood in the liver. In this study, CD-1 mice were prenatally exposed to 20 μg/kg/day, 200 μg/kg/day, 500 mg/kg/day, or 750 mg/kg/day DEHP from gestational day (GD) 10. Read More

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http://dx.doi.org/10.1016/j.taap.2020.115123DOI Listing

Knock-out of MicroRNA 145 impairs cardiac fibroblast function and wound healing post-myocardial infarction.

J Cell Mol Med 2020 Jul 6. Epub 2020 Jul 6.

Toronto General Research Institute, University Health Network, Toronto, ON, Canada.

Prevention of infarct scar thinning and dilatation and stimulation of scar contracture can prevent progressive heart failure. Since microRNA 145 (miR-145) plays an important role in cardiac fibroblast response to wound healing and cardiac repair after an myocardial infarction (MI), using a miR-145 knock-out (KO) mouse model, we evaluated contribution of down-regulation of miR-145 to cardiac fibroblast and myofibroblast function during adverse cardiac remodelling. Cardiac function decreased more and the infarct size was larger in miR-145 KO than that in WT mice after MI and this phenomenon was accompanied by a decrease in cardiac fibroblast-to-myofibroblast differentiation. Read More

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http://dx.doi.org/10.1111/jcmm.15597DOI Listing

Association between Neonatal birth weight and risk of maternal glucose intolerance after gestational diabetes mellitus.

J Diabetes Investig 2020 Jul 6. Epub 2020 Jul 6.

Department of Obstetrics and Gynaecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Aims: To evaluate whether the neonatal birth weight(NBW) is associated with early postpartum glucose intolerance in women with gestational diabetes mellitus(GDM).

Methods: A total of 1113 women diagnosed with GDM who completed oral glucose tolerance test at 6-9 weeks postpartum between April 1 2014 and January 8 2020, were included in this observational prospective cohort study. They were grouped by neonatal birthweight quartiles and odds ratios of postpartum glucose intolerance for different levels of neonatal birth weight were assessed. Read More

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http://dx.doi.org/10.1111/jdi.13349DOI Listing

Dual-trigger improves the outcomes of in vitro fertilization cycles in older patients with diminished ovarian reserve: A retrospective cohort study.

PLoS One 2020 6;15(7):e0235707. Epub 2020 Jul 6.

Department of Obstetrics and Gynecology, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan.

Background: Dual-trigger for final oocyte maturation has been applied on the women with poor ovarian response or diminished ovarian reserve. However, the results were controversial. The Patient-Oriented Strategies Encompassing IndividualizeD Oocyte Number (POSEIDON) stratification is a set of newly established criteria for low prognosis patients. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235707PLOS

Parents' smoking onset before conception as related to body mass index and fat mass in adult offspring: Findings from the RHINESSA generation study.

PLoS One 2020 6;15(7):e0235632. Epub 2020 Jul 6.

Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.

Emerging evidence suggests that parents' preconception exposures may influence offspring health. We aimed to investigate maternal and paternal smoking onset in specific time windows in relation to offspring body mass index (BMI) and fat mass index (FMI). We investigated fathers (n = 2111) and mothers (n = 2569) aged 39-65 years, of the population based RHINE and ECRHS studies, and their offspring aged 18-49 years (n = 6487, mean age 29. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235632PLOS

Association between vitamin D level and bronchopulmonary dysplasia: A systematic review and meta-analysis.

PLoS One 2020 6;15(7):e0235332. Epub 2020 Jul 6.

Department of Pediatrics, Konkuk University Medical Center, Seoul, Republic of Korea.

Neonatal vitamin D deficiency is common and is associated with development of pulmonary disease in children and adults. While the role of vitamin D in normal lung development is well established, the association between vitamin D deficiency and bronchopulmonary dysplasia (BPD) remains unclear. The present meta-analysis was conducted to evaluate the relationship between vitamin D and BPD. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235332PLOS

Prevalence and associated factors of delayed first antenatal care booking among reproductive age women in Ethiopia; a multilevel analysis of EDHS 2016 data.

PLoS One 2020 6;15(7):e0235538. Epub 2020 Jul 6.

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Early or timely initiation of antenatal care and regular visits based on the schedule have a tremendous effect on both maternal and fetal health. Despite the paramount benefits of early initiation of ANC within the first 12 weeks of pregnancy, women still do not have adequate and equal access to high-quality early antenatal care.

Objective: To determine the prevalence and factors associated with delayed first ANC booking in Ethiopia. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235538PLOS

Susceptibility of Armigeres subalbatus Coquillett (Diptera: Culicidae) to Zika virus through oral and urine infection.

PLoS Negl Trop Dis 2020 Jul 6;14(7):e0008450. Epub 2020 Jul 6.

Department of Vector Biology and Control, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.

Background: Zika virus (ZIKV) disease outbreaks have been occurring in South America since 2015, and has spread to North America. Because birth defects and cases of Guillain Barré have been associated with infection with ZIKV, this has drawn global attention. ZIKV is generally considered an Aedes-transmitted pathogen. Read More

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http://dx.doi.org/10.1371/journal.pntd.0008450DOI Listing

Giving birth and dying alone in hospital during the COVID-19 pandemic - a time for shifting paradigm toward continuity of care.

J Perinat Med 2020 Jul 6. Epub 2020 Jul 6.

Department of Anatomy, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.

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http://dx.doi.org/10.1515/jpm-2020-0220DOI Listing

Prenatal screening diagnosis and management in the era of coronavirus: the Sardinian experience.

J Perinat Med 2020 Jul 7. Epub 2020 Jul 7.

Department of Obstetrics and Gynecology, Prenatal and Preimplantation Genetic Diagnosis, Fetal Therapy, Microcitemico Pediatric Hospital "Antonio Cao", Cagliari, Sardinia, Italy.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new coronavirus, was first identified in December 2019 in Wuhan, China and spread rapidly, affecting many other countries. The disease is now referred to as coronavirus disease 2019 (COVID-19).The Italian government declared a state of emergency on 31st January 2020 and on 11th March World Health Organization (WHO) officially declared the COVID-19 outbreak a global pandemic. Read More

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http://dx.doi.org/10.1515/jpm-2020-0208DOI Listing

Prenatal Exposures to Perfluoroalkyl Acids and Associations with Markers of Adiposity and Plasma Lipids in Infancy: An Odense Child Cohort Study.

Environ Health Perspect 2020 Jul 6;128(7):77001. Epub 2020 Jul 6.

Department of Environmental Medicine, University of Southern Denmark, Odense, Denmark.

Background: Perfluoroalkyl acids (PFAA) are repellants that cross the placental barrier, enabling interference with fetal programming. Maternal PFAA concentrations have been associated with offspring obesity and dyslipidemia in childhood and adulthood, but this association has not been studied in infancy.

Objectives: We investigated associations between maternal PFAA concentrations and repeated markers of adiposity and lipid metabolism in infancy. Read More

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http://dx.doi.org/10.1289/EHP5184DOI Listing

TETANUS VACCINE DURING PREGNANCY: DATA OF A TERTIARY HOSPITAL IN TURKEY.

Turk J Med Sci 2020 Jul 6. Epub 2020 Jul 6.

Background/aim: To evaluate the prevalence of tetanus vaccination in pregnant women, and to determine the factors affecting the vaccination and barriers to the vaccination.

Materials And Methods: We conducted an observational-descriptive study with 494 patients who gave birth in Etlik Zubeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkey. Participants were divided into two groups; vaccinated and not-vaccinated. Read More

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http://dx.doi.org/10.3906/sag-2001-77DOI Listing

[Scientific and practical contribution of professor M.F. Tsytovich in the development of domestic otorhinolaryngology (to the 150th anniversary from his birth)].

Vestn Otorinolaringol 2020 ;85(3):100-103

V.I. Razumovsky Saratov State Medical University of the Ministry of Health of Russia, Saratov, Russia.

The article presents biographical information about Professor M.F. Tsytovich, reflecting his scientific and practical contribution to the formation and development of domestic otorhinolaryngology, to the training of scientific and pedagogical personnel, as well as characterizing his social activities in the first half of the twentieth century. Read More

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http://dx.doi.org/10.17116/otorino202085031100DOI Listing
January 2020

A reduction in reported alcohol use in pregnancy in Australian Aboriginal communities: a prevention campaign showing promise.

Aust N Z J Public Health 2020 Jul 6. Epub 2020 Jul 6.

Telethon Kids Institute, The University of Western Australia, Perth, Western Australia.

Objective: Aboriginal leaders in remote Western Australian communities with high rates of prenatal alcohol exposure invited researchers to evaluate the community-led Marulu foetal alcohol spectrum disorder (FASD) Prevention Strategy initiated in 2010.

Methods: The proportion of women reporting alcohol use during pregnancy to midwives was compared between 2008, 2010 and 2015. Initial midwife appointments were calculated by weeks of gestation. Read More

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http://dx.doi.org/10.1111/1753-6405.13012DOI Listing

Evaluation of Color Difference in Placenta with Twin Anemia Polycythemia Sequence.

J Vis Exp 2020 Jun 17(160). Epub 2020 Jun 17.

Division of Neonatology, Department of Pediatrics, Leiden University Medical Center;

Twin anemia polycythemia sequence (TAPS) occurs in 5% of monochorionic twins and is characterized by large inter-twin hemoglobin differences. The postnatal diagnostic criteria for TAPS are based on hematologic parameters and placental characteristics. Placental examination after birth shows that color of the maternal side between placental territories of the anemic and polycythemic twins is remarkably different. Read More

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http://dx.doi.org/10.3791/61312DOI Listing

Effect of a Health System-Sponsored Mobile App on Perinatal Health Behaviors: Retrospective Cohort Study.

JMIR Mhealth Uhealth 2020 Jul 6;8(7):e17183. Epub 2020 Jul 6.

Center for Outcomes Research and Education, Providence Portland Medical Center, Portland, OR, United States.

Background: Pregnancy mobile apps are becoming increasingly popular, with parents-to-be seeking information related to their pregnancy and their baby through mobile technology. This increase raises the need for prenatal apps with evidence-based content that is personalized and reliable. Previous studies have looked at whether prenatal apps impact health and behavior outcomes among pregnant and postpartum individuals; however, research has been limited. Read More

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http://dx.doi.org/10.2196/17183DOI Listing

Hyperketonemia GWAS and parity dependent SNP associations in Holstein dairy cows intensively sampled for blood β-hydroxybutyrate concentration.

Physiol Genomics 2020 Jul 6. Epub 2020 Jul 6.

Department of Dairy Science, University of Wisconsin, United States.

Hyperketonemia (HYK) is a metabolic disorder that affects early postpartum dairy cows; however, there has been limited success in identifying genomic variants contributing to HYK susceptibility. We conducted a genome-wide association study (GWAS) using HYK phenotypes based on an intensive screening protocol, interrogated genotype interactions with parity group (GWIS), and evaluated the enrichment of annotated metabolic pathways. Holstein cows were enrolled onto the experiment after parturition and blood samples were collected at 4 timepoints between 5 to 18 days postpartum. Read More

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http://dx.doi.org/10.1152/physiolgenomics.00016.2020DOI Listing

Changes in oxidative stress markers in plasma of sows during periparturient period.

Authors:
M Szczubiał

Pol J Vet Sci 2020 Jun;23(1):185-190

Department and Clinic of Animal Reproduction, Faculty of Veterinary Medicine, University of Life Sciences, Głęboka 30, 20-612 Lublin, Poland.

The aim of the present study was to determine changes in oxidative status in plasma of sows during periparturient period using markers of lipid and protein peroxidation intensity. Plasma from 12 pregnant gilts collected on days 14 and 1 before parturition and on days 1, 7 and 14 postpartum was used in the study. As indicators of alterations in the oxidative status, plasma concentrations of thiobarbituric acid reactive substances (TBARS) and sulphydryl groups (SH groups) were measured spectrophotometrically, as well as plasma concentrations of bityrosine and formylokinurenine were determined by the spectrofluorimetric method. Read More

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http://dx.doi.org/10.24425/pjvs.2020.132764DOI Listing

Galectin-7 overexpression destroy airway epithelial barrier in transgenic mice.

Integr Zool 2020 Jul 6. Epub 2020 Jul 6.

Department of Respiratory Medicine II, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China.

When the integrity of airway epithelium is destroyed, the ordered airway barrier no longer exists and increase sensitivity to viral infections and allergens, leading to the occurrence of airway inflammation such as asthma. Here, we found that galectin-7 transgenic(+) mice exhibited abnormal airway structures as embryos and after birth. These abnormalities included absent or substantially reduced pseudostratified columnar ciliated epithelium and increased monolayer cells with irregular arrangement and widening of intercellular spaces. Read More

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http://dx.doi.org/10.1111/1749-4877.12463DOI Listing

Changes in Cardiometabolic Risk Factors Before and After Gestational Diabetes: A Prospective Life-Course Analysis in CARDIA Women.

Obesity (Silver Spring) 2020 Jul 6. Epub 2020 Jul 6.

Cardiovascular and Metabolic Conditions Section, Division of Research, Kaiser Permanente Northern California, Oakland, California, USA.

Objective: This study hypothesized that both preconception and postchildbearing patterns of cardiometabolic risk factors may be different for women with gestational diabetes mellitus (GDM) compared with women without GDM.

Methods: Among 1,302 (51% black) women in the Coronary Artery Risk Development in Young Adults (CARDIA) study with births and followed for 30 years, this study evaluated changes in cardiometabolic factors (BMI, waist circumference [WC], lipids, blood pressure) during prechildbearing (prior to the first postbaseline birth) and postchildbearing periods (after the last birth) by GDM status using piecewise linear mixed models adjusted for sociodemographics, parity, and time-varying covariates.

Results: Compared with women who did not develop GDM, weight and WC increases in women who developed GDM (n = 152, 12%) were faster (BMI difference: +0. Read More

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http://dx.doi.org/10.1002/oby.22848DOI Listing

Clinical characteristics of children with congenital Zika syndrome: a case series.

Arq Neuropsiquiatr 2020 Jun 29. Epub 2020 Jun 29.

Pontifícia Universidade Católica de São Paulo, Curso de Fisioterapia, Departamento Teorias e Métodos em Fisioterapia e Fonoaudiologia, São Paulo SP, Brazil.

Background: The congenital Zika syndrome involves structural brain changes, including ventriculomegaly, thin cerebral cortices, abnormal gyral pattern, cortical malformations, hypoplasia of the corpus callosum, myelination delay, subcortical diffuse calcifications, brainstem hypoplasia, and microcephaly in newborns.

Objective: This study aimed to describe the clinical characteristics of children with congenital Zika syndrome; to compare the outcomes of infants infected in the first (1T, n=20) and second trimesters of pregnancy (2T, n=11); to investigate correlations between birth weight, birth and follow-up head circumference, birth gestational age, and gross motor scores.

Methods: Participants were evaluated with Alberta Infant Motor Scale (AIMS) and part A of the Gross Motor Function Measure (GMFM-A). Read More

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http://dx.doi.org/10.1590/0004-282X20200020DOI Listing

Effect of prenatal nutritional intervention on foetal growth restriction: a real-world study in Shenzhen, China.

J Matern Fetal Neonatal Med 2020 Jul 6:1-10. Epub 2020 Jul 6.

Guangzhou Key Laboratory of Environmental Pollution and Health Assessment, Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.

Fetal growth restriction (FGR) is the primary cause of infant morbidity and mortality. Although nutritional intervention is generally used to cure FGR, its effects on early- and late-onset FGR have not been reported. This study aimed to resolve this issue in a real-world setting. Read More

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http://dx.doi.org/10.1080/14767058.2020.1786512DOI Listing

Assessment of social factors influencing hospitalization cost of US preterm newborns, 2016.

Authors:
Fu-Sheng Chou

J Matern Fetal Neonatal Med 2020 Jul 6:1-9. Epub 2020 Jul 6.

Division of Neonatology, Department of Pediatrics, Loma Linda University, Loma Linda, CA, USA.

Preterm newborn (PTN) care is costly in the US, and the preterm birth (PTB) rate has not seen substantial improvement. PTB remains a significant public health issue because of risks of adverse health outcomes and the associated economic burden. Assessing factors leading to high hospital cost is imperative in order to ease economic burden associated with PTB. Read More

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http://dx.doi.org/10.1080/14767058.2020.1776252DOI Listing

Marijuana Use for Women: To Prescribe or Not to Prescribe.

Subst Use Misuse 2020 Jul 5:1-2. Epub 2020 Jul 5.

Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

The marijuana policy varies greatly worldwide. Marijuana use is illegal in most countries. Nevertheless, the medical potentials of marijuana have been increasingly uncovered, and its use by women is increasing. Read More

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http://dx.doi.org/10.1080/10826084.2020.1782938DOI Listing

Evaluation of the new expert consensus-based definition of selective fetal growth restriction in monochorionic pregnancies.

J Matern Fetal Neonatal Med 2020 Jul 6:1-7. Epub 2020 Jul 6.

Department of Obstetrics and Gynecology, University Hospital Brugmann, Université Libre de Bruxelles, Brussels, Belgium.

To compare the outcomes of a cohort of monochorionic pregnancies with selective fetal growth restriction (sFGR) diagnosed according to the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) definition published in 2015 with a cohort considered as sFGR according to new expert consensus-based diagnostic parameters published in 2019. This was a retrospective study, conducted between January 1st 2010 and July 30th 2019. We reviewed the medical records of all the monochorionic pregnancies followed in our center including perinatal outcomes. Read More

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http://dx.doi.org/10.1080/14767058.2020.1786053DOI Listing

Management of sickle cell disease during pregnancy: experience in a third-level hospital and future recommendations.

J Matern Fetal Neonatal Med 2020 Jul 6:1-9. Epub 2020 Jul 6.

Department of Obstetrics and Gynecology, University Hospital Brugmann, Université Libre de Bruxelles, Brussels, Belgium.

To describe the outcomes of sickle-cell disease in pregnancy according to the different treatments adopted before and during pregnancy and to propose a systematic approach to treat sickle-cell disease (SCD) during pregnancy. A retrospective descriptive study compared pregnancy outcomes among women with SCD who stopped hydroxyurea (HU) once pregnant (Group 1), were never treated before and during pregnancy (Group 2) or were treated by HU before conception who received prophylactic transfusion during pregnancy (Group 3). For each group we recorded the population's characteristics and the transfusion-related, obstetrical, perinatal and SCD complications. Read More

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http://dx.doi.org/10.1080/14767058.2020.1786054DOI Listing

Comparison of the combination of recombinant follicle-stimulating hormone and recombinant luteinizing hormone protocol versus human menopausal gonadotropin protocol in controlled ovarian stimulation: A systematic review and meta-analysis.

J Evid Based Med 2020 Jul 6. Epub 2020 Jul 6.

Chinese Evidence-based Medicine Center and CREAT Group, West China Hospital, Sichuan University, Chengdu, PR China.

Objective: To systematically review the efficacy of a combination of recombinant follicle-stimulating hormone (rFSH) and recombinant luteinizing hormone (rLH) protocol versus human menopausal gonadotropin (hMG) protocol in controlled ovarian stimulation (COS).

Methods: PubMed, EMbase, The Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, and WanFang Data were searched to collect studies published prior to January 2019 on the efficacy of rFSH combined with rLH versus hMG alone in COS. Two reviewers independently screened the literature, conducted the data extraction, and assessed the risk of bias for all selected studies. Read More

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http://dx.doi.org/10.1111/jebm.12390DOI Listing

Minimization of bias in measures of gestational weight gain.

Obes Rev 2020 Jul 6. Epub 2020 Jul 6.

Department of Women's and Children's Health, University of Otago, Dunedin, New Zealand.

Gestational weight gain (GWG) is an important predictor of adverse pregnancy outcomes including gestational diabetes, preterm birth, delivery by caesarean and post-partum weight retention. The Institute of Medicine guidelines on GWG are widely adopted, and GWG is widely researched as an outcome of interest in lifestyle interventions during pregnancy. However, estimation of prepregnancy weight and measurement of weight prior to delivery introduce bias into measures of GWG. Read More

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http://dx.doi.org/10.1111/obr.13056DOI Listing

Prenatal tobacco exposure and psychiatric outcomes in adolescence: is the effect mediated through birth weight?

Acta Psychiatr Scand 2020 Jul 6. Epub 2020 Jul 6.

Department of Psychology, Royal College of Surgeons in Ireland, Dublin, Ireland.

Objective: This study aims to examine the associations between prenatal exposure to maternal smoking, birthweight and persistent offspring psychiatric symptoms. Additionally we aim to examine whether the relationship between prenatal maternal smoking and persistent offspring psychiatric symptoms is mediated by offspring birthweight.

Methods: This study used the Growing Up in Ireland (GUI) longitudinal cohort. Read More

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http://dx.doi.org/10.1111/acps.13210DOI Listing

The usefulness of periostin determination in gynecology and obstetrics.

Ginekol Pol 2020 ;91(6):364-351

Department of Physiotherapy, Higher School of Physical Education, Wroclaw, Poland.

Periostin (POSTN) is a multifunctional glycoprotein that belongs to the group of extracellular matrix (ECM) proteins. Due to the molecular structure, cellular interactions, tissue locations as well functions of POSTN, we realize that its pivotal role is organization and regulation of ECM microenvironment. In available databases there is a lack of data summarizing current knowledge about POSTN expression in the field of gynecology and obstetrics. Read More

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http://dx.doi.org/10.5603/GP.2020.0064DOI Listing
January 2020

Comments on a recent case-control study of malignant mesothelioma of the pericardium and the tunica vaginalis testis.

Scand J Work Environ Health 2020 Jul 6. Epub 2020 Jul 6.

Health Sciences, Exponent, Inc., 149 Commonwealth Drive, Menlo Park, California, 94025, USA.

As the first case-control study of malignant mesothelioma of the pericardium and the tunica vaginalis testis (mTVT), the paper by Marinaccio et al (1) is potentially an important epidemiologic contribution. A careful review of the paper, however, raises a number of methodological issues. Any case-control study can be viewed as being nested within a conceptual cohort, with controls being sampled from the at-risk cohort as cases arise over time. Read More

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http://dx.doi.org/10.5271/sjweh.3909DOI Listing

Efficacy of antiepileptic drugs in neonatal seizures: a systematic review protocol.

BMJ Paediatr Open 2020 29;4(1):e000683. Epub 2020 Jun 29.

Key Laboratory of Obstetrics & Gynecologic and Pediatric Diseases and Birth Defects of the Ministry of Education, Sichuan University, Chengdu, China.

Introduction: Seizures are one of the most common neurological disorders of neonates, which is also an emergency in the neonatal intensive care unit. For neonates, the recommended first-line antiepileptic drugs (AEDs) include phenobarbitone, which may be effective in only 50% of seizures. Some new AEDs, such as levetiracetam, have been shown to be effective in adults and older children. Read More

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http://dx.doi.org/10.1136/bmjpo-2020-000683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326240PMC

Comparison of Machine Learning Methods and Conventional Logistic Regressions for Predicting Gestational Diabetes Using Routine Clinical Data: A Retrospective Cohort Study.

J Diabetes Res 2020 12;2020:4168340. Epub 2020 Jun 12.

Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.

Background: Gestational diabetes mellitus (GDM) contributes to adverse pregnancy and birth outcomes. In recent decades, extensive research has been devoted to the early prediction of GDM by various methods. Machine learning methods are flexible prediction algorithms with potential advantages over conventional regression. Read More

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http://dx.doi.org/10.1155/2020/4168340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306091PMC

Age-Period-Cohort Analysis of Type 2 Diabetes Mortality Attributable to Particulate Matter Pollution in China and the U.S.

J Diabetes Res 2020 11;2020:1243947. Epub 2020 Jun 11.

Department of Preventive Medicine, School of Health Sciences, Wuhan University, Wuhan 430071, China.

Aim: We aimed to assess and compare secular trends in type 2 diabetes mortality attributable to particulate matter pollution in China and U.S.

Methods: We performed an age-period-cohort (APC) analysis to estimate the independent effects of age, period, and cohort on mortality of type 2 diabetes attributable to particulate matter pollution. Read More

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http://dx.doi.org/10.1155/2020/1243947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306083PMC

The Role of circRNA-SETD2/miR-519a/PTEN Axis in Fetal Birth Weight through Regulating Trophoblast Proliferation.

Biomed Res Int 2020 12;2020:9809632. Epub 2020 Jun 12.

Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, China ).

Abnormal birth weight is the one of the major causes of adulthood diseases such as obesity, metabolic syndrome, cardiovascular disease, type 2 diabetes, and hypertension. Accumulating evidence has suggested that the placental trophoblast is one of the most important reasons that influence birth weight. Our previous study showed that miR-519a are correlated with low fetal birth weight through regulating trophoblast proliferation. Read More

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http://dx.doi.org/10.1155/2020/9809632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306081PMC

Intramuscular progesterone versus 8% Crinone vaginal gel for luteal phase support following blastocyst cryopreserved single embryo transfer: a retrospective cohort study.

Fertil Res Pract 2020 1;6:10. Epub 2020 Jul 1.

Department of Obstetrics & Gynecology, Brigham & Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115 USA.

Background: The optimal route of progesterone administration for luteal support in cryopreserved embryo transfer (CET) has been the subject of much debate. While most published research has pertained to day 3 transfers, recent data on blastocyst CET has suggested that intramuscular progesterone (IMP) is superior to twice daily vaginal Endometrin suppositories for luteal phase support, resulting in significantly higher ongoing pregnancy rates. This study aimed to determine whether IMP is similarly superior to 8% Crinone vaginal gel for luteal phase support following blastocyst CET. Read More

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http://dx.doi.org/10.1186/s40738-020-00079-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329474PMC

Postpartum meloxicam administration alters plasma haptoglobin, polyunsaturated fatty acid, and oxylipid concentrations in postpartum ewes.

J Anim Sci Biotechnol 2020 1;11:68. Epub 2020 Jul 1.

Department of Animal Science, Iowa State University, Ames, IA USA.

Background: Postpartum inflammation is a natural and necessary response; however, a dysfunctional inflammatory response can be detrimental to animal productivity. The objective of this study was to determine the effects of a non-steroidal anti-inflammatory drug (meloxicam) on ewe postpartum inflammatory response, ewe plasma polyunsaturated fatty acid and oxylipid concentrations, and lamb growth.

Results: After lambing, 36 Hampshire and Hampshire × Suffolk ewes were sequentially assigned within type of birth to control ( = 17) or meloxicam orally administered on d 1 and 4 of lactation (MEL; 90 mg,  = 19). Read More

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http://dx.doi.org/10.1186/s40104-020-00473-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329520PMC

Impact of Nutrition Support Team on Postoperative Nutritional Status and Outcome of Patients with Congenital Gastrointestinal Anomalies.

Middle East J Dig Dis 2020 Apr;12(2):116-122

Department of Pediatrics, Mashhad University of Medical Science, Mashhad, Iran.

BACKGROUND The aim of this study was to evaluate postoperative nutritional status in patients who underwent operations due to congenital gastrointestinal anomalies in surgical neonatal intensive care units (NICUs) and to investigate the role of nutrition support teams (NSTs) on the outcome. METHODS A retrospective clinical study was carried out at two NICUs in Dr. Sheikh Pediatric Hospital, Mashhad, Iran. Read More

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http://dx.doi.org/10.34172/mejdd.2020.171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320989PMC

Appropriate age range for introduction of complementary feeding into an infant's diet.

EFSA J 2019 Sep 12;17(9):e05780. Epub 2019 Sep 12.

Following a request from the European Commission, the Panel on Nutrition, Novel Foods and Food Allergens (NDA) revised its 2009 Opinion on the appropriate age for introduction of complementary feeding of infants. This age has been evaluated considering the effects on health outcomes, nutritional aspects and infant development, and depends on the individual's characteristics and development. As long as foods have an age-appropriate texture, are nutritionally appropriate and prepared following good hygiene practices, there is no convincing evidence that at any age investigated in the included studies (< 1 to < 6 months), the introduction of complementary foods (CFs) is associated with adverse health effects or benefits (except for infants at risk of iron depletion). Read More

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http://dx.doi.org/10.2903/j.efsa.2019.5780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009265PMC
September 2019

Partial trisomy 4q and monosomy 5p inherited from a maternal translocationt(4;5)(q33; p15) in three adverse pregnancies.

Mol Cytogenet 2020 30;13:26. Epub 2020 Jun 30.

Department of Prenatal Diagnosis Medical Center of Xuzhou Central Hospital, Xuzhou Clinical Schools of Xuzhou Medical University and Nanjing Medical University, 199 South Jiefang Road, Xuzhou, 221009 Jiangsu China.

Background: Carriers of balanced reciprocal chromosomal translocations are at known reproductive risk for offspring with unbalanced genotypes and resultantly abnormal phenotypes. Once fertilization of a balanced translocation gamete with a normal gamete, the partial monosomy or partial trisomy embryo will undergo abortion, fetal arrest or fetal malformations. We reported a woman with chromosomal balanced translocation who had two adverse pregnancies. Read More

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http://dx.doi.org/10.1186/s13039-020-00492-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329393PMC