1,781 results match your criteria Bipolar disorders[Journal]


Retinal vascular abnormalities in schizophrenia and bipolar disorder: A window to the brain.

Bipolar Disord 2019 Apr 22. Epub 2019 Apr 22.

Dept. of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.

Objectives: The examination of retinal microvascular abnormalities through fundus photography is currently the best available non-invasive technique for assessment of cerebral vascular status. Several studies in the last decade have reported higher incidences of adverse cerebrovascular events in Schizophrenia (SCZ) and bipolar disorder (BD). However, retinal microvasculature abnormalities in SCZ and BD have remained under-explored, and no study has compared this aspect of SCZ and BD till date. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/bdi.12779
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http://dx.doi.org/10.1111/bdi.12779DOI Listing
April 2019
1 Read

Agitated depression in bipolar disorder.

Bipolar Disord 2019 Apr 20. Epub 2019 Apr 20.

Psychological Medicine, University of Worcester, UK.

Objectives: It has been suggested that agitated depression (AD) is a common, severe feature in bipolar disorder. We aimed to estimate the prevalence of AD and investigate whether presence of AD was associated with episodic and lifetime clinical features in a large well-characterised bipolar disorder sample.

Method: The prevalence of agitation, based on semi-structured interview and medical case-notes, in the most severe depressive episode was estimated in 2925 individuals with DSM-IV bipolar disorder recruited into the UK Bipolar Disorder Research Network. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/bdi.12778
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http://dx.doi.org/10.1111/bdi.12778DOI Listing
April 2019
1 Read

Data impress… but beliefs seduce.

Authors:
Michael Gitlin

Bipolar Disord 2019 Apr 20. Epub 2019 Apr 20.

Geffen School of Medicine at UCLA.

Aside from the quest/development of a reliable diagnostic system-e.g. the DSM and/or ICD- in which the meanings and definitions of words and diagnoses are consensually agreed upon, the most important development in modern clinical psychiatry has been the evolution of a data base of clinical studies, using research designs so that efficacy can be demonstrated by studies as opposed to being opined by one expert or another. Read More

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http://dx.doi.org/10.1111/bdi.12777DOI Listing

Lamotrigine, bipolar disorder, and the pill-free week.

Authors:
Arne Reimers

Bipolar Disord 2019 Mar 28. Epub 2019 Mar 28.

Department of Clinical Chemistry and Pharmacology, Division of Laboratory Medicine, Lund, Sweden.

Lamotrigine (LTG) was introduced in 1991 as one of the first second-generation antiepileptic drugs, and very soon its mood-stabilizing effects were discovered. Today, LTG is one of the most used drugs for epilepsy and mood disorders, especially in women. Because it is devoid of enzyme-inducing properties, LTG does not affect the efficacy of hormonal contraception like most of the first-generation antiepileptic drugs (AEDs) do. Read More

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http://dx.doi.org/10.1111/bdi.12776DOI Listing

Commentary on chronic mood instability: Bipolar, borderline or both?

Bipolar Disord 2019 Mar 19. Epub 2019 Mar 19.

Clinica Psichiatrica, Dipartimento di Medicina, Sperimentale University of Pisa, Pisa, Toscany, Italy.

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http://dx.doi.org/10.1111/bdi.12774DOI Listing

Functional outcome assessment in bipolar disorder: A systematic literature review.

Bipolar Disord 2019 Mar 18. Epub 2019 Mar 18.

Department of Psychiatry & Behavioral Sciences, University of New Mexico, Albuquerque, New Mexico.

Objectives: Functional impairment is an important driver of disability in patients with bipolar disorder (BD) and can persist even when symptomatic remission has been achieved. The objectives of this systematic literature review were to identify studies that assessed functioning in patients with BD and describe the functional scales used and their implementation.

Methods: A systematic literature review of English-language articles published between 2000 and 2017 reporting peer-reviewed, original research related to functional assessment in patients with BD was conducted. Read More

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http://dx.doi.org/10.1111/bdi.12775DOI Listing
March 2019
2 Reads

Welcome Letter.

Bipolar Disord 2019 Mar;21 Suppl 1

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http://dx.doi.org/10.1111/bdi.12754DOI Listing

Conference Committee.

Authors:

Bipolar Disord 2019 Mar;21 Suppl 1

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http://dx.doi.org/10.1111/bdi.12755DOI Listing

Keynote Lectures.

Authors:

Bipolar Disord 2019 Mar;21 Suppl 1:8-10

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http://dx.doi.org/10.1111/bdi.12758DOI Listing

Light modulation for bipolar disorder: A commentary on "An update on adjunctive treatment options for bipolar disorder" by Dean et al. (2018).

Bipolar Disord 2019 Mar 18. Epub 2019 Mar 18.

Department of Neuropsychiatry, Faculty of Medicine, Oita University, Yufu-city, Oita, Japan.

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http://dx.doi.org/10.1111/bdi.12773DOI Listing
March 2019
1 Read

New drug candidates for bipolar disorder-A nation-wide population-based study.

Bipolar Disord 2019 Mar 14. Epub 2019 Mar 14.

Department of Biostatistics, University of Copenhagen, Copenhagen, Denmark.

Objective: Drug repurposing is an increasingly promising idea in many fields of medicine. We systematically used Danish nation-wide population-based registers to investigate whether continued use of non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs), low-dose aspirin, high-dose aspirin, statins, allopurinol, and angiotensin agents decrease the rate of incident mania/bipolar disorder.

Methods: A nation-wide population-based longitudinal study using Poisson regression analyses including all persons in Denmark who purchased the exposure medication of interest and a random sample of 30% of the Danish population. Read More

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http://dx.doi.org/10.1111/bdi.12772DOI Listing
March 2019
2 Reads

Mood episodes are associated with increased cortical thinning: A longitudinal study of bipolar disorder type II.

Bipolar Disord 2019 Mar 12. Epub 2019 Mar 12.

Norwegian Centre for Mental Disorders Research (NORMENT), K.G. Jebsen Centre for Psychosis Research, Oslo University Hospital, Oslo, Norway.

Objectives: Previous studies found evidence for thinner frontotemporal cortices in bipolar disorder (BD), yet whether this represents a stable disease trait or an effect of mood episodes remains unknown. Here, we assessed the reproducibility of thinner frontotemporal cortices in BD type II, compared longitudinal changes in cortical thickness between individuals with BD type II and healthy controls (HCs), and examined the effect of mood episodes on cortical thickness change.

Methods: Thirty-three HCs and 29 individuals with BD type II underwent 3T magnetic resonance imaging at baseline, as published previously, and 2. Read More

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http://doi.wiley.com/10.1111/bdi.12771
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http://dx.doi.org/10.1111/bdi.12771DOI Listing
March 2019
3 Reads

Longitudinal proton spectroscopy study of the prefrontal cortex in youth at risk for bipolar disorder before and after their first mood episode.

Bipolar Disord 2019 Mar 12. Epub 2019 Mar 12.

Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH.

Objectives: To investigate neurochemical abnormalities in the left and right ventrolateral prefrontal cortex (VLPFC) and anterior cingulate cortex (ACC) of youth at risk for bipolar disorder using proton magnetic resonance spectroscopy before and after their first mood episode.

Methods: Children and adolescents offspring of parents with bipolar I disorder (at-risk group, n = 117) and matched healthy controls (HC group, n = 61) were recruited at the University of Cincinnati. At-risk subjects had no lifetime major mood and psychotic disorders at baseline, and were followed up every 4 months to monitor for development of a major depressive, manic, hypomanic, or mixed mood episode. Read More

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http://dx.doi.org/10.1111/bdi.12770DOI Listing
March 2019
4.965 Impact Factor

Laboratories should provide a separate therapeutic range for serum lithium levels in maintenance treatment of older adults with bipolar disorder (OABD).

Bipolar Disord 2019 Mar 12. Epub 2019 Mar 12.

Department of Old Age Psychiatry, GGZinGeest/Vumc, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1111/bdi.12769DOI Listing
March 2019
1 Read

Neural mechanisms of face emotion processing in youths and adults with bipolar disorder.

Bipolar Disord 2019 Mar 9. Epub 2019 Mar 9.

San Diego State University/University of California, San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA.

Objectives: Little is known about potential differences in the pathophysiology of bipolar disorder (BD) across development. The present study aimed to characterize age-related neural mechanisms of BD.

Methods: Youths and adults with and without BD (N = 108, age range = 9. Read More

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http://dx.doi.org/10.1111/bdi.12768DOI Listing
March 2019
1 Read

Longitudinal brain functional changes between mania and euthymia in bipolar disorder.

Bipolar Disord 2019 Mar 8. Epub 2019 Mar 8.

FIDMAG Germanes Hospitalàries Research Foundation, Barcelona, Spain.

Objectives: While widespread cortical and subcortical brain functional abnormalities have been found in bipolar disorder, the changes that take place between illness phases to recovery are less clearly documented. Only a small number of longitudinal studies of manic patients, in particular, have been carried out.

Methods: Twenty-six bipolar patients underwent fMRI during performance of the n-back working memory task when manic and again after recovery. Read More

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http://dx.doi.org/10.1111/bdi.12767DOI Listing
March 2019
1 Read

That which does not kill you-May afflict you? Psychological trauma in bipolar disorder.

Bipolar Disord 2019 Feb 27. Epub 2019 Feb 27.

Centre Fòrum Research Unit, Institut de Neuropsiquiatria i Addiccions, Barcelona, Spain.

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http://dx.doi.org/10.1111/bdi.12766DOI Listing
February 2019
1 Read

Retigabine-ezogabine: A new treatment option for bipolar disorder?

Bipolar Disord 2019 Feb 27. Epub 2019 Feb 27.

Department of Geriatrics, Neuroscience and Orthopedics, Institute of Psychiatry and Psychology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.

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http://doi.wiley.com/10.1111/bdi.12762
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http://dx.doi.org/10.1111/bdi.12762DOI Listing
February 2019
26 Reads

Successful lithium treatment in a patient on hemodialysis.

Bipolar Disord 2019 Feb 12. Epub 2019 Feb 12.

Antes Center for Mental Health Care, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1111/bdi.12756DOI Listing
February 2019
3 Reads

Lithium treatment for chronic traumatic encephalopathy: A proposal.

Bipolar Disord 2019 Mar 13;21(2):104-105. Epub 2019 Mar 13.

Forensic Pathologist/Neuropathologist/Epidemiologist, San Joaquin County Sheriff-Coroner/Chief Medical Examiner. Clinical Professor of Medical Pathology and Laboratory Medicine, University of California, Davis, California.

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http://dx.doi.org/10.1111/bdi.12757DOI Listing
March 2019
1 Read

Lithium and the Woozle effect.

Authors:
Tammas Kelly

Bipolar Disord 2019 Feb 9. Epub 2019 Feb 9.

Department of Psychiatry and Behavioral Sciences, George Washington University, Washington, District of Columbia.

Objectives: Lithium is the oldest and most-studied treatment for bipolar depression. Many treatment guidelines place lithium as a top treatment recommendation for bipolar depression; yet some guidelines do not recommend lithium at all. These discrepancies were explored by examining the following errors: the Woozle effect (evidence by citation), reference inflation (overreporting the findings of cited studies) and belief perseverance (maintaining a belief despite new contradictory evidence) as possible causes for these discrepancies. Read More

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http://dx.doi.org/10.1111/bdi.12753DOI Listing
February 2019

Combined oral anticonceptives and the pill-free week in two bipolar patients treated with lamotrigine.

Bipolar Disord 2019 Feb 7. Epub 2019 Feb 7.

Department of Psychiatry, GGZ inGeest De Nieuwe Valerius, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/bdi.12751DOI Listing
February 2019
1 Read

Predictive modeling for response to lithium and quetiapine in bipolar disorder.

Bipolar Disord 2019 Feb 7. Epub 2019 Feb 7.

The Dauten Family Center for Bipolar Treatment Innovation, Massachusetts General Hospital, Boston, Massachusetts.

Objectives: Lithium and quetiapine are known to be effective treatments for bipolar disorder. However, little information is available to inform prediction of response to these medications. Machine-learning methods can identify predictors of response by examining variables simultaneously. Read More

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http://dx.doi.org/10.1111/bdi.12752DOI Listing
February 2019
4 Reads

Clinical staging model in bipolar disorder: A few considerations.

Bipolar Disord 2019 Feb 6. Epub 2019 Feb 6.

Department of Psychiatry and NDDTC, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1111/bdi.12750DOI Listing
February 2019
1 Read

Differences in serum uric acid between 'unipolar' and 'bipolar' depression: Preliminary data.

Bipolar Disord 2019 Feb 2. Epub 2019 Feb 2.

Department of Medicine and Surgery, University of Milano Bicocca, Milano, Italy.

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http://dx.doi.org/10.1111/bdi.12749DOI Listing
February 2019
1 Read

The need for prospective longitudinal cohort studies on the clinical staging models in bipolar disorder-A commentary to the study by van der Markt et al, 2018.

Bipolar Disord 2019 Jan 22. Epub 2019 Jan 22.

Department O, Copenhagen Affective Disorder Research Center (CADIC), Psychiatric Center Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/bdi.12742DOI Listing
January 2019

Anxiety comorbidity in older adults with bipolar disorders: Overlooked and underappreciated.

Bipolar Disord 2019 Mar 15;21(2):174-175. Epub 2019 Feb 15.

Department of Psychiatry and of Neurology, Case Western Reserve University School of Medicine, Cleveland, Ohio.

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http://doi.wiley.com/10.1111/bdi.12741
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http://dx.doi.org/10.1111/bdi.12741DOI Listing
March 2019
9 Reads

Comorbid bipolar and obsessive-compulsive disorders: A commentary.

Bipolar Disord 2019 Jan 21. Epub 2019 Jan 21.

Mood Disorders Program, Tufts Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1111/bdi.12740DOI Listing
January 2019
1 Read

Deficits in frontoparietal activation and anterior insula functional connectivity during regulation of cognitive-affective interference in bipolar disorder.

Bipolar Disord 2018 Nov 22. Epub 2018 Nov 22.

Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Objectives: Bipolar disorders (BD) are characterized by emotion and cognitive dysregulation. Mapping deficits in the neurocircuitry of cognitive-affective regulation allows for potential identification of intervention targets. This study used functional MRI data in BD patients and healthy controls during performance on a task requiring cognitive and inhibitory control superimposed on affective images, assessing cognitive and affective interference. Read More

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http://dx.doi.org/10.1111/bdi.12709DOI Listing
November 2018
1 Read

Mogens Schou (1918-2005): A scientist, a doctor and a lithium champion.

Bipolar Disord 2018 12;20(8):680-682

Department of Psychiatry, Aalborg University Hospital, Aalborg, Denmark.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/bdi.12739
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http://dx.doi.org/10.1111/bdi.12739DOI Listing
December 2018
24 Reads

Commentary on Simon et al. 2018: "Comparative economic evaluation of quetiapine plus lamotrigine combination vs quetiapine monotherapy (and folic acid vs placebo) in patients with bipolar depression (CEQUEL)".

Authors:
Denise Razzouk

Bipolar Disord 2019 Mar 6;21(2):170-171. Epub 2019 Jan 6.

Centre of Economic Mental Health, Department of Psychiatry, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.

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http://dx.doi.org/10.1111/bdi.12738DOI Listing
March 2019
1 Read

The microbiome in bipolar depression: A longitudinal study of one pair of monozygotic twins.

Bipolar Disord 2019 Feb 3;21(1):93-97. Epub 2019 Feb 3.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/bdi.12736
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http://dx.doi.org/10.1111/bdi.12736DOI Listing
February 2019
4 Reads

Ethanol normalizes glutamate-induced elevation of intracellular sodium in olfactory neuroepithelial progenitors from subjects with bipolar illness but not nonbipolar controls: Biologic evidence for the self-medication hypothesis.

Bipolar Disord 2019 Mar 3;21(2):179-181. Epub 2019 Feb 3.

Mood Disorders Research Program, Department of Psychiatry and Behavioral Medicine, University of Louisville School of Medicine, Louisville, Kentucky.

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http://dx.doi.org/10.1111/bdi.12737DOI Listing
March 2019
2 Reads

The metabolic basis of psychosis in bipolar disorder: A positron emission tomography study.

Bipolar Disord 2019 Mar 1;21(2):151-158. Epub 2018 Dec 1.

Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.

Objectives: Psychotic symptoms are a common feature in bipolar disorder (BD), especially during manic phases, and are associated with a more severe course of illness. However, not all bipolar subjects experience psychosis during the course of their illness, and this difference often guides assessment and pharmacological treatment. The aim of the present study is to elucidate, for the first time, the FDG uptake dysfunctions associated with psychosis in BD patients with and without a history of past psychotic symptoms, through a positron emission tomography (PET) approach. Read More

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http://dx.doi.org/10.1111/bdi.12710DOI Listing
March 2019
3 Reads

Bottom-up gamma and bipolar disorder, clinical and neuroepigenetic implications.

Bipolar Disord 2019 Mar 28;21(2):108-116. Epub 2018 Dec 28.

Center for Translational Neuroscience, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

Objectives: This limited review examines the role of the reticular activating system (RAS), especially the pedunculopontine nucleus (PPN), one site of origin of bottom-up gamma, in the symptoms of bipolar disorder (BD).

Methods: The expression of neuronal calcium sensor protein 1 (NCS-1) in the brains of BD patients is increased. It has recently been found that all PPN neurons manifest intrinsic membrane beta/gamma frequency oscillations mediated by high threshold calcium channels, suggesting that it is one source of bottom-up gamma. Read More

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http://dx.doi.org/10.1111/bdi.12735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441386PMC
March 2019
2 Reads

Differences between unipolar mania and bipolar-I disorder: Evidence from nine epidemiological studies.

Bipolar Disord 2018 Nov 26. Epub 2018 Nov 26.

Department of Psychiatry, University Hospital of Lausanne, Prilly, Switzerland.

Objectives: Although clinical evidence suggests important differences between unipolar mania and bipolar-I disorder (BP-I), epidemiological data are limited. Combining data from nine population-based studies, we compared subjects with mania (M) or mania with mild depression (Md) to those with BP-I with both manic and depressive episodes with respect to demographic and clinical characteristics in order to highlight differences.

Methods: Participants were compared for gender, age, age at onset of mania, psychiatric comorbidity, temperament, and family history of mental disorders. Read More

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http://doi.wiley.com/10.1111/bdi.12732
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http://dx.doi.org/10.1111/bdi.12732DOI Listing
November 2018
13 Reads

What is early intervention in bipolar disorder? Recommendation of a pragmatic way focusing on early intervention in patients with newly diagnosed bipolar disorder.

Authors:
Lars V Kessing

Bipolar Disord 2019 Mar 14;21(2):168-169. Epub 2018 Dec 14.

The Copenhagen Affective Disorder Research Center, Psychiatric Center Copenhagen, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/bdi.12733DOI Listing
March 2019
2 Reads

Aspirin for recurrence prevention in bipolar disorder-Promising, yet clinically understudied?

Bipolar Disord 2019 Feb 19;21(1):13-15. Epub 2018 Dec 19.

Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/bdi.12731DOI Listing
February 2019
3 Reads

Compliance with the guidelines for laboratory monitoring of patients treated with lithium: A retrospective follow-up study among ambulatory patients in the Netherlands.

Bipolar Disord 2018 Nov 25. Epub 2018 Nov 25.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

Objectives: Laboratory monitoring of patients using lithium is important to prevent harm and to increase effectiveness. The aim of this study is to determine compliance with the guidelines for laboratory monitoring of patients treated with lithium overall and within subgroups.

Methods: Patients having at least one lithium dispensing for 6 months or longer between January 2010 and December 2015 were identified retrospectively using data from the Dutch PHARMO Database Network. Read More

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http://dx.doi.org/10.1111/bdi.12730DOI Listing
November 2018
15 Reads

A report of affective switching associated with ketamine: The case of ketamine-induced mania is not closed.

Bipolar Disord 2019 Mar 1;21(2):176-178. Epub 2019 Feb 1.

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1111/bdi.12728DOI Listing
March 2019
1 Read

Testing a clinical staging model for bipolar disorder using longitudinal life chart data.

Bipolar Disord 2018 Nov 17. Epub 2018 Nov 17.

Department of Psychiatry, Amsterdam Public Health, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Objective: Bipolar disorder has a wide range of clinical manifestations which may progress over time. The aim of this study was to test the applicability of a clinical staging model for bipolar disorder and to gain insight into the nature of the variables influencing progression through consecutive stages.

Methods: Using retrospectively reported longitudinal life chart data of 99 subjects from the Stanley Foundation Bipolar Network Naturalistic Follow-up Study, the occurrence, duration and timely sequence of stages 2-4 were determined per month. Read More

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http://doi.wiley.com/10.1111/bdi.12727
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http://dx.doi.org/10.1111/bdi.12727DOI Listing
November 2018
16 Reads

Acquired mania associated with a left temporal meningioma.

Bipolar Disord 2018 12 16;20(8):774-777. Epub 2018 Nov 16.

Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.

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http://doi.wiley.com/10.1111/bdi.12711
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http://dx.doi.org/10.1111/bdi.12711DOI Listing
December 2018
15 Reads

Neural signatures of the risk for bipolar disorder: A meta-analysis of structural and functional neuroimaging studies.

Bipolar Disord 2018 Nov 16. Epub 2018 Nov 16.

Department of Medicine (DAME), University of Udine, Udine, Italy.

Objective: Widespread functional and structural alterations in the brain have been extensively reported in unaffected relatives (RELs) of patients with bipolar disorder (BD) who are at genetic risk for BD. A sufficiently powered meta-analysis of structural (sMRI) and functional magnetic resonance imaging (fMRI) alterations in RELs is still lacking.

Methods: Functional and structural magnetic resonance imaging studies investigating RELs and healthy controls (HCs) published by July 2017 were included in the meta-analyses. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/bdi.12720
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http://dx.doi.org/10.1111/bdi.12720DOI Listing
November 2018
12 Reads

Use of gray sunglasses to alleviate hypomanic state in two patients with bipolar II disorder.

Bipolar Disord 2019 Mar 29;21(2):182-184. Epub 2019 Jan 29.

Department of Neuropsychiatry, Faculty of Medicine, Oita University, Yufu-city, Oita, Japan.

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http://doi.wiley.com/10.1111/bdi.12725
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http://dx.doi.org/10.1111/bdi.12725DOI Listing
March 2019
7 Reads