1,761 results match your criteria Bipolar disorders[Journal]


Successful lithium treatment in a patient on hemodialysis.

Bipolar Disord 2019 Feb 12. Epub 2019 Feb 12.

Antes Center for Mental Health Care, Rotterdam, the Netherlands.

In 2010 a 69-year old patient with bipolar I disorder, type 2 diabetes and hypertension was referred to the Nephrology outpatient clinic of the Maasstad Hospital for progressive kidney disease. Her creatinine was 205 μmol/L (estimated Glomerular Filtration Rate (eGFR) 22 mL/min/1.73m ). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12756DOI Listing
February 2019
2 Reads

Lithium treatment for chronic traumatic encephalopathy: A proposal.

Bipolar Disord 2019 Feb 12. Epub 2019 Feb 12.

Forensic Pathologist/Neuropathologist/Epidemiologist, San Joaquin County Sheriff-Coroner/Chief Medical Examiner. Clinical Professor of Medical Pathology and Laboratory Medicine, University of California, Davis.

Chronic traumatic encephalopathy (CTE) is a diagnosis recently discovered and described in the context of American football. It is a a neurodegenerative disease that is a consequence of repetitive brain injury such as concussion. Such injury most notably occurs in physically violent sports but can also occur in other settings, such as during military duty, where explosive blasts can cause subconcussive impacts to the head. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12757DOI Listing
February 2019
1 Read

Lithium and the Woozle effect.

Authors:
Tammas Kelly

Bipolar Disord 2019 Feb 9. Epub 2019 Feb 9.

Psychiatry and Behavioral Sciences George Washington University GWU MFA, Department of Psychiatry and Behavioral Sciences, 2120 L St NW, Suite 600, Washington, DC, 20037.

Lithium is the oldest and most-studied treatment for bipolar depression. Many treatment guidelines place Lithium as a top treatment recommendation for bipolar depression; yet some guidelines don't recommend lithium at all. These discrepancies were explored by examining the following errors: the Woozle effect (evidence by citation), reference inflation (overreporting the findings of cited studies) and belief perseverance (maintaining a belief despite new contradictory evidence) as possible causes for these discrepancies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12753DOI Listing
February 2019

Combined oral anticonceptives (COC) and the pill-free week in two bipolar patients treated with lamotrigine.

Bipolar Disord 2019 Feb 7. Epub 2019 Feb 7.

Department of Psychiatry, GGZ inGeest De Nieuwe Valerius, Amstelveenseweg 589, 1081, JC, Amsterdam, The Netherlands.

Lamotrigine plasma concentrations are potentially lowered up to 60% due to interaction with combined oral anticonceptives containing ethinyl estradiol. Our clinical experience is that this variability does not influence mood stability or side-effects. A pill-free week may be safe when treating stable bipolar disorder, but there is no evidence for this claim. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12751DOI Listing
February 2019
1 Read

Predictive modeling for response to lithium and quetiapine in bipolar disorder.

Bipolar Disord 2019 Feb 7. Epub 2019 Feb 7.

The Dauten Family Center for Bipolar Treatment Innovation, Massachusetts General Hospital, Boston, MA.

Objectives: Lithium and quetiapine are known to be effective treatments for bipolar disorder. However, little information is available to inform prediction of response to these medications. Machine-learning methods can identify predictors of response by examining variables simultaneously. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12752DOI Listing
February 2019
3 Reads

Clinical staging model in Bipolar disorder: A few considerations.

Bipolar Disord 2019 Feb 6. Epub 2019 Feb 6.

Department of Psychiatry and NDDTC, All India Institute of Medical Sciences, New Delhi, India, 110029.

Staging of psychiatric disorders can serve various purposes. Not only are they helpful for prognostication, they can also be linked to treatment approaches best suited to a particular phase of the disorder. Though there have been attempts at staging psychiatric disorders, there remains a void of universally accepted and implemented staging mechanisms and criteria for these illnesses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12750DOI Listing
February 2019
1 Read

Differences in serum uric acid between 'unipolar' and 'bipolar' depression: Preliminary data.

Bipolar Disord 2019 Feb 5. Epub 2019 Feb 5.

Department of Medicine and Surgery, University of Milano Bicocca, Milano, Italy.

Uric acid is the end-product of adenosine catabolism, influenced by the activity of the enzymes adenosine deaminase and xanthine oxidase. In recent years novel research has been conducted on the role of serum uric acid in both bipolar and major depressive disorders, possibly based on the imbalance of purinergic system metabolism. Despite some limitations, our previous meta-analysis preliminarily estimated increased levels of serum uric acid in subjects suffering from bipolar disorder as compared with both healthy controls and individuals with major depressive disorder. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12749DOI Listing
February 2019
1 Read

The International Consortium Investigating Neurocognition in Bipolar Disorder (ICONIC-BD).

Bipolar Disord 2019 Feb 5. Epub 2019 Feb 5.

Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London& South London, London, England, UK.

Bipolar Disorder (BD) is the 4 leading cause of disability worldwide among young people ages 10-24 years. Although the diagnosis is largely defined by the mood episodes associated with the illness, cognitive deficits are among the most persistent and disabling symptoms of illness and have a profound impact on clinical course and functional outcome. Specifically, trait-like impairment is common in the domains of attention, verbal learning, and executive function; these deficits contribute to functional disability and are targets for emerging treatments and preventions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12748DOI Listing
February 2019
2 Reads

Comparative economic evaluation of quetiapine plus lamotrigine combination vs quetiapine monotherapy(and folic acid vs placebo) in patients with bipolar depression (CEQUEL).

Bipolar Disord 2019 Jan 30. Epub 2019 Jan 30.

Research Office Hospital Moinhos de Vento - Porto alegre, Brazil.

Economic evaluations in the field of psychiatry are still scarce. The article by Simon et al (2018) is unique as it proposes a comparative economic analysis of the association between lamotrigine and quetiapine (first-line treatment) in acute bipolar depression . Different economic analyses have already been performed with lamotrigine for disorders such as epilepsy, borderline personality disorder, and Lennox-Gastaut Syndrome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12747DOI Listing
January 2019
2 Reads

The need for prospective longitudinal cohort studies on the clinical staging models in bipolar disorder-A commentary to the study by van der Markt et al, 2018.

Bipolar Disord 2019 Jan 22. Epub 2019 Jan 22.

Department O, Copenhagen Affective Disorder Research Center (CADIC), Psychiatric Center Copenhagen, Copenhagen, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12742DOI Listing
January 2019

Anxiety comorbidity in older adults with bipolar disorders: Overlooked and underappreciated.

Bipolar Disord 2019 Jan 22. Epub 2019 Jan 22.

Department of Psychiatry and of Neurology, Case Western Reserve University School of Medicine, Cleveland, Ohio.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12741
Publisher Site
http://dx.doi.org/10.1111/bdi.12741DOI Listing
January 2019
5 Reads

Comorbid bipolar and obsessive-compulsive disorders: A commentary.

Bipolar Disord 2019 Jan 21. Epub 2019 Jan 21.

Mood Disorders Program, Tufts Medical Center, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12740DOI Listing
January 2019
1 Read

Deficits in frontoparietal activation and anterior insula functional connectivity during regulation of cognitive-affective interference in bipolar disorder.

Bipolar Disord 2018 Nov 22. Epub 2018 Nov 22.

Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Objectives: Bipolar disorders (BD) are characterized by emotion and cognitive dysregulation. Mapping deficits in the neurocircuitry of cognitive-affective regulation allows for potential identification of intervention targets. This study used functional MRI data in BD patients and healthy controls during performance on a task requiring cognitive and inhibitory control superimposed on affective images, assessing cognitive and affective interference. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12709DOI Listing
November 2018
1 Read

Mogens Schou (1918-2005): A scientist, a doctor and a lithium champion.

Bipolar Disord 2018 Dec;20(8):680-682

Department of Psychiatry, Aalborg University Hospital, Aalborg, Denmark.

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/bdi.12739
Publisher Site
http://dx.doi.org/10.1111/bdi.12739DOI Listing
December 2018
17 Reads

Commentary on Simon et al. 2018: "Comparative economic evaluation of quetiapine plus lamotrigine combination vs quetiapine monotherapy (and folic acid vs placebo) in patients with bipolar depression (CEQUEL)".

Authors:
Denise Razzouk

Bipolar Disord 2018 Dec 11. Epub 2018 Dec 11.

Centre of Economic Mental Health, Department of Psychiatry, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12738DOI Listing
December 2018
1 Read

The microbiome in bipolar depression: A longitudinal study of one pair of monozygotic twins.

Bipolar Disord 2018 Dec 9. Epub 2018 Dec 9.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/bdi.12736
Publisher Site
http://dx.doi.org/10.1111/bdi.12736DOI Listing
December 2018
2 Reads

Ethanol normalizes glutamate-induced elevation of intracellular sodium in olfactory neuroepithelial progenitors from subjects with bipolar illness but not nonbipolar controls: Biologic evidence for the self-medication hypothesis.

Bipolar Disord 2018 Dec 9. Epub 2018 Dec 9.

Mood Disorders Research Program, Department of Psychiatry and Behavioral Medicine, University of Louisville School of Medicine, Louisville, Kentucky.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12737DOI Listing
December 2018
2 Reads

The metabolic basis of psychosis in bipolar disorder: A positron emission tomography study.

Bipolar Disord 2018 Dec 1. Epub 2018 Dec 1.

Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.

Objectives: Psychotic symptoms are a common feature in bipolar disorder (BD), especially during manic phases, and are associated with a more severe course of illness. However, not all bipolar subjects experience psychosis during the course of their illness, and this difference often guides assessment and pharmacological treatment. The aim of the present study is to elucidate, for the first time, the FDG uptake dysfunctions associated with psychosis in BD patients with and without a history of past psychotic symptoms, through a positron emission tomography (PET) approach. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12710DOI Listing
December 2018
2 Reads

Bottom-up gamma and bipolar disorder, clinical and neuroepigenetic implications.

Bipolar Disord 2018 Dec 1. Epub 2018 Dec 1.

Center for Translational Neuroscience, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

Objectives: This limited review examines the role of the reticular activating system (RAS), especially the pedunculopontine nucleus (PPN), one site of origin of bottom-up gamma, in the symptoms of bipolar disorder (BD).

Methods: The expression of neuronal calcium sensor protein 1 (NCS-1) in the brains of BD patients is increased. It has recently been found that all PPN neurons manifest intrinsic membrane beta/gamma frequency oscillations mediated by high threshold calcium channels, suggesting that it is one source of bottom-up gamma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12735DOI Listing
December 2018
2 Reads

Differences between unipolar mania and bipolar-I disorder: Evidence from nine epidemiological studies.

Bipolar Disord 2018 Nov 26. Epub 2018 Nov 26.

Department of Psychiatry, University Hospital of Lausanne, Prilly, Switzerland.

Objectives: Although clinical evidence suggests important differences between unipolar mania and bipolar-I disorder (BP-I), epidemiological data are limited. Combining data from nine population-based studies, we compared subjects with mania (M) or mania with mild depression (Md) to those with BP-I with both manic and depressive episodes with respect to demographic and clinical characteristics in order to highlight differences.

Methods: Participants were compared for gender, age, age at onset of mania, psychiatric comorbidity, temperament, and family history of mental disorders. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12732
Publisher Site
http://dx.doi.org/10.1111/bdi.12732DOI Listing
November 2018
10 Reads

What is early intervention in bipolar disorder? Recommendation of a pragmatic way focusing on early intervention in patients with newly diagnosed bipolar disorder.

Authors:
Lars V Kessing

Bipolar Disord 2018 Nov 26. Epub 2018 Nov 26.

The Copenhagen Affective Disorder Research Center, Psychiatric Center Copenhagen, University of Copenhagen, Copenhagen, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12733DOI Listing
November 2018
2 Reads

Aspirin for recurrence prevention in bipolar disorder-Promising, yet clinically understudied?

Bipolar Disord 2018 Nov 25. Epub 2018 Nov 25.

Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12731DOI Listing
November 2018
2 Reads

Compliance with the guidelines for laboratory monitoring of patients treated with lithium: A retrospective follow-up study among ambulatory patients in the Netherlands.

Bipolar Disord 2018 Nov 25. Epub 2018 Nov 25.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

Objectives: Laboratory monitoring of patients using lithium is important to prevent harm and to increase effectiveness. The aim of this study is to determine compliance with the guidelines for laboratory monitoring of patients treated with lithium overall and within subgroups.

Methods: Patients having at least one lithium dispensing for 6 months or longer between January 2010 and December 2015 were identified retrospectively using data from the Dutch PHARMO Database Network. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12730DOI Listing
November 2018
10 Reads

A report of affective switching associated with ketamine: The case of ketamine-induced mania is not closed.

Bipolar Disord 2018 Nov 19. Epub 2018 Nov 19.

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12728DOI Listing
November 2018
1 Read

Testing a clinical staging model for bipolar disorder using longitudinal life chart data.

Bipolar Disord 2018 Nov 17. Epub 2018 Nov 17.

Department of Psychiatry, Amsterdam Public Health, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Objective: Bipolar disorder has a wide range of clinical manifestations which may progress over time. The aim of this study was to test the applicability of a clinical staging model for bipolar disorder and to gain insight into the nature of the variables influencing progression through consecutive stages.

Methods: Using retrospectively reported longitudinal life chart data of 99 subjects from the Stanley Foundation Bipolar Network Naturalistic Follow-up Study, the occurrence, duration and timely sequence of stages 2-4 were determined per month. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12727
Publisher Site
http://dx.doi.org/10.1111/bdi.12727DOI Listing
November 2018
10 Reads

Acquired mania associated with a left temporal meningioma.

Bipolar Disord 2018 Dec 16;20(8):774-777. Epub 2018 Nov 16.

Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12711
Publisher Site
http://dx.doi.org/10.1111/bdi.12711DOI Listing
December 2018
9 Reads

Neural signatures of the risk for bipolar disorder: A meta-analysis of structural and functional neuroimaging studies.

Bipolar Disord 2018 Nov 16. Epub 2018 Nov 16.

Department of Medicine (DAME), University of Udine, Udine, Italy.

Objective: Widespread functional and structural alterations in the brain have been extensively reported in unaffected relatives (RELs) of patients with bipolar disorder (BD) who are at genetic risk for BD. A sufficiently powered meta-analysis of structural (sMRI) and functional magnetic resonance imaging (fMRI) alterations in RELs is still lacking.

Methods: Functional and structural magnetic resonance imaging studies investigating RELs and healthy controls (HCs) published by July 2017 were included in the meta-analyses. Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/bdi.12720
Publisher Site
http://dx.doi.org/10.1111/bdi.12720DOI Listing
November 2018
8 Reads

Use of gray sunglasses to alleviate hypomanic state in two patients with bipolar II disorder.

Bipolar Disord 2018 Nov 14. Epub 2018 Nov 14.

Department of Neuropsychiatry, Faculty of Medicine, Oita University, Yufu-city, Oita, Japan.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12725
Publisher Site
http://dx.doi.org/10.1111/bdi.12725DOI Listing
November 2018
7 Reads

Affective temperaments are associated with the white matter microstructure in healthy participants.

Bipolar Disord 2018 Nov 14. Epub 2018 Nov 14.

Department of Neurosurgery, Faculty of Medicine, Oita University, Oita, Japan.

Objectives: Five affective temperaments are regarded as potential precursors of bipolar disorder. These are depressive, cyclothymic, hyperthymic, irritable, and anxious temperaments. However, the neural substrates underlying these temperaments have not been identified. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12726DOI Listing
November 2018
1 Read

Secondary mania as a possible presentation of a C9orf72 hexanucleotide repeat expansion.

Bipolar Disord 2018 Nov 14. Epub 2018 Nov 14.

Department of Old Age Psychiatry, GGZ inGeest/VU University Medical Center, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12724DOI Listing
November 2018
4 Reads

Daily and weekly mood ratings using a remote capture method in high-risk offspring of bipolar parents: Compliance and symptom monitoring.

Bipolar Disord 2018 Nov 13. Epub 2018 Nov 13.

Department of Psychiatry, University of Oxford, Oxford, UK.

Objectives: To determine the compliance and clinical utility of weekly and daily electronic mood symptom monitoring in adolescents and young adults at risk for mood disorder.

Methods: Fifty emerging adult offspring of bipolar parents were recruited from the Flourish Canadian high-risk offspring cohort study along with 108 university student controls. Participants were assessed by KSADS/SADS-L semi-structured interviews and used a remote capture method to complete weekly and daily mood symptom ratings using validated scales for 90 consecutive days. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12721DOI Listing
November 2018
2 Reads

Weight gain as a predictor of frontal and temporal lobe volume loss in bipolar disorder: A prospective MRI study.

Bipolar Disord 2018 Nov 13. Epub 2018 Nov 13.

Mood Disorders Centre, University of British Columbia, Vancouver, British Columbia, Canada.

Objectives: A sizable fraction of people with bipolar I disorder (BDI) experience a deteriorating clinical course with increasingly frequent mood episodes and chronic disability. This is believed to result from neurobiological illness progression, or neuroprogression. Excessive weight gain predicts neuroprogression across multiple brain illnesses, but no prospective studies have investigated this in BDI. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12722DOI Listing
November 2018
10 Reads

Elevated mirror neuron system activity in bipolar mania: Evidence from a transcranial magnetic stimulation study.

Bipolar Disord 2018 Nov 13. Epub 2018 Nov 13.

Department of Psychiatry, National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore, India.

Objectives: The role of the "mirror neuron system" (MNS) in the pathophysiology of mood disorders is not well studied. Given its posited role in the often-impaired socio-emotional processes like intention detection, empathy, and imitation, we compared putative MNS-activity in patients with bipolar mania and healthy comparison subjects. We also examined the association between putative MNS-activity and hyper-imitative behaviors in patients. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12723
Publisher Site
http://dx.doi.org/10.1111/bdi.12723DOI Listing
November 2018
10 Reads

Reduced cerebrovascular reactivity among adolescents with bipolar disorder.

Bipolar Disord 2018 Nov 13. Epub 2018 Nov 13.

Centre for Youth Bipolar Disorder, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

Objectives: Cardiovascular disease (CVD) is excessive and premature among individuals with bipolar disorder (BD). Cerebrovascular reactivity (CVR), reflecting vasodilatory capacity of cerebral blood vessels in response to vasoactive substances, is a marker of cerebrovascular health. Despite informative findings in other diseases, CVR has not previously been examined in BD. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12719
Publisher Site
http://dx.doi.org/10.1111/bdi.12719DOI Listing
November 2018
10 Reads

Lithium monotherapy associated longitudinal effects on resting state brain networks in clinical treatment of bipolar disorder.

Bipolar Disord 2018 Nov 12. Epub 2018 Nov 12.

Center for Behavioral Health, Cleveland Clinic Foundation, Cleveland, Ohio.

Objectives: Lithium is one of the most effective and specific treatments for bipolar disorder (BP), but the neural mechanisms by which lithium impacts symptoms remain unclear. Past research has been limited by a reliance on cross-sectional designs, which does not allow for identification of within-person changes due to lithium and has not examined communication between brain regions (ie, networks). In the present study, we prospectively investigated the lithium monotherapy associated effects in vivo on the brain connectome in medication-free BP patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12718DOI Listing
November 2018
3 Reads

Second-generation antipsychotic long-acting injections in bipolar disorder: Systematic review and meta-analysis.

Bipolar Disord 2018 Dec 11;20(8):687-696. Epub 2018 Nov 11.

School of Life and Health Sciences, Aston University, Birmingham, UK.

Background: Non-adherence is a significant problem in bipolar disorder. Second-generation antipsychotics (SGA) long-acting injections (LAIs) may improve adherence in bipolar disorder and may prevent relapses. However, the evidence is limited and conflicting. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12707DOI Listing
December 2018
2 Reads

Is obesity changing the phenotype of bipolar disorder from predominately euphoric toward mixed presentations?

Authors:
Roger S McIntyre

Bipolar Disord 2018 Dec 28;20(8):685-686. Epub 2018 Nov 28.

University of Toronto, Toronto, Canada.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12717
Publisher Site
http://dx.doi.org/10.1111/bdi.12717DOI Listing
December 2018
10 Reads

Overhauling technology-based interventions for young people with bipolar disorder: Lessons learned from adults.

Bipolar Disord 2018 Nov 2. Epub 2018 Nov 2.

Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12716DOI Listing
November 2018
2 Reads

Patterns of changes in bipolar depressive symptoms revealed by trajectory analysis among 482 patients with bipolar disorder.

Bipolar Disord 2018 Nov 1. Epub 2018 Nov 1.

Dauten Family Center for Bipolar Treatment Innovation, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.

Introduction: Depressive episodes are often prevalent among patients with bipolar disorder, but little is known regarding the differential patterns of development over time. We aimed to determine and characterize trajectories of depressive symptoms among adults with bipolar disorder during 6 months of systematic treatment.

Methods: The pragmatic clinical trial, Bipolar Clinical Health Outcomes Initiative in Comparative Effectiveness (CHOICE), randomized 482 outpatients with bipolar disorder to lithium or quetiapine. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12715
Publisher Site
http://dx.doi.org/10.1111/bdi.12715DOI Listing
November 2018
8 Reads

Obesity, mixed, and bipolar features in major depression: Should we identify the usual suspects or also look for covert mediators?

Bipolar Disord 2018 Dec 16;20(8):772-773. Epub 2018 Nov 16.

INSERM UMRS1144, Paris, France.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12712
Publisher Site
http://dx.doi.org/10.1111/bdi.12712DOI Listing
December 2018
8 Reads

Delphi survey of maintenance lithium treatment in older adults with bipolar disorder: An ISBD task force report.

Bipolar Disord 2018 Oct 30. Epub 2018 Oct 30.

Department of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio.

Objectives: Despite the growing numbers and proportion of older adults with bipolar disorder (OABD), there are very limited guidelines for the use of lithium with its double-edged potential for effectiveness and toxicity in this population. The primary aims of this Delphi survey were: (a) To determine the place of lithium among the preferred choices for maintenance treatment of OABD. (b) To provide detailed clinical guidelines for the safe and effective use of lithium in OABD. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12714
Publisher Site
http://dx.doi.org/10.1111/bdi.12714DOI Listing
October 2018
17 Reads

Comparative economic evaluation of quetiapine plus lamotrigine combination vs quetiapine monotherapy (and folic acid vs placebo) in patients with bipolar depression (CEQUEL).

Bipolar Disord 2018 Dec 17;20(8):733-745. Epub 2018 Dec 17.

Department of Health Economics, Center for Public Health, Medical University of Vienna, Vienna, Austria.

Objectives: Although not licensed for acute bipolar depression, lamotrigine has evidence for efficacy in trials and its use is recommended in guidelines. So far there had been no prospective health economic evaluation of its use.

Methods: Cost-utility analysis of the CEQUEL trial comparing quetiapine plus lamotrigine vs quetiapine monotherapy (and folic acid vs placebo in an add-on factorial design) for patients with bipolar depression (n = 201) from the health and social care perspective. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12713DOI Listing
December 2018
4 Reads

Serum uric acid as a predictor of bipolarity in individuals with a major depressive episode.

Bipolar Disord 2018 Oct 30. Epub 2018 Oct 30.

Psychiatry Department, Coimbra Hospital and University Centre, Coimbra, Portugal.

Objectives: There are no well-established biomarkers to predict the risk of conversion to bipolar disorder (BD) in patients with depression. Given the putative role of purinergic neurotransmission dysfunction in BD, the purpose of our study was to evaluate if higher serum uric acid (UA) levels could predict BD conversion in depressed inpatients.

Methods: We reviewed retrospectively the records of subjects hospitalized between June 2007 and June 2010 with a diagnosis of major depressive disorder (MDD) who had undergone routine UA levels testing at admission. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12708
Publisher Site
http://dx.doi.org/10.1111/bdi.12708DOI Listing
October 2018
28 Reads

Targeting the gut to achieve improved outcomes in mood disorders.

Authors:
Felice N Jacka

Bipolar Disord 2018 Oct 25. Epub 2018 Oct 25.

Food & Mood Centre, IMPACT Strategic Research Centre, School of Medicine, Deakin University, Barwon Health, Geelong, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12706DOI Listing
October 2018
1 Read

Can obesity in a major depressive episode be considered as a biomarker for bipolar spectrum disorders?

Authors:
Keming Gao

Bipolar Disord 2018 Oct 25. Epub 2018 Oct 25.

Mood and Anxiety Clinic in the Mood Disorders Program of the Department of Psychiatry, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/bdi.12705
Publisher Site
http://dx.doi.org/10.1111/bdi.12705DOI Listing
October 2018
9 Reads

Investigating the complex relationship between bipolarity and obesity: "Not because it is easy, but because it is hard".

Authors:
David J Bond

Bipolar Disord 2018 Oct 25. Epub 2018 Oct 25.

Department of Psychiatry, University of Minnesota Medical School, Minneapolis, Minnesota.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12703DOI Listing
October 2018
1 Read

Modelling mood disorders: An ACE solution?

Bipolar Disord 2018 11;20 Suppl 2:4-16

Sophisticated Mood Appraisal & Refinement of Treatment (SMART) Group.

Objectives: The treatment of mood disorders remains sub-optimal. A major reason for this is our lack of understanding of the underlying pathophysiology of depression and bipolar disorder. A core problem is the lack of specificity of our current diagnoses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12700DOI Listing
November 2018
1 Read

Treating depression with adjunctive antipsychotics.

Bipolar Disord 2018 11;20 Suppl 2:17-24

Sophisticated Mood Appraisal & Refinement of Treatment (SMART) Group.

Objectives: To evaluate the efficacy and safety of using adjunctive antipsychotics in patients with major depressive disorder.

Method: Studies published since the last Cochrane review conducted in 2010 were identified via a literature search of recognised databases, using the keywords "adjunct*", "augment*", "antipsychotic" and "depression", and systematically evaluated. A targeted review of relevant guidelines was undertaken. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bdi.12701DOI Listing
November 2018
1 Read