Harnessing a Methane-Fueled, Sediment-Free Mixed Microbial Community for Utilization of Distributed Sources of Natural Gas.
- Jeffrey J Marlow,
- Amit Kumar,
- Brandon Enalls,
- Linda M Reynard,
- Noreen Tuross,
- Gregory Stephanopoulos,
- Peter Girguis
Biotechnol Bioeng 2018 Feb 20. Epub 2018 Feb 20.
Department of Organismic & Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
Harnessing the metabolic potential of uncultured microbial communities is a compelling opportunity for the biotechnology industry, an approach that would vastly expand the portfolio of usable feedstocks. Methane is particularly promising because it is abundant and energy-rich, yet the most efficient methane-activating metabolic pathways involve mixed communities of anaerobic methanotrophic archaea and sulfate reducing bacteria. These communities oxidize methane at high catabolic efficiency and produce chemically reduced by-products at a comparable rate and in near-stoichiometric proportion to methane consumption. Read More