5 results match your criteria Biotarget[Journal]

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Mesenchymal stem cell derived extracellular vesicles: a promising new therapeutic approach for hepatic injury.

Biotarget 2017 Sep 19;1. Epub 2017 Sep 19.

Departments of Transplantation and Cancer Biology, Mayo Clinic, Jacksonville, Florida, USA.

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http://dx.doi.org/10.21037/biotarget.2017.08.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130825PMC
September 2017

Vacuolar H-ATPases (V-ATPases) as therapeutic targets: a brief review and recent developments.

Biotarget 2017 Dec 13;1. Epub 2017 Dec 13.

Departments of Orthodontics and Anatomy & Cell Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.

Vacuolar H-ATPases (V-ATPases) are multi-subunit enzymes that play housekeeping roles in eukaryotic cells by acidifying lysosomes, late endosomes, Golgi, and other membrane-bounded compartments. Beyond that, V-ATPases have specialized functions in certain cell types linked to diseases including osteoporosis and cancer. Efforts to identify strategies to develop inhibitors selective for V-ATPases that are involved in disease progression have been ongoing for more than two decades, but so far have not yielded a therapeutic agent that has been translated to the clinic. Read More

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http://dx.doi.org/10.21037/biotarget.2017.12.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448788PMC
December 2017
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Stimulatory role of exosomes in the context of therapeutic anti-cancer vaccines.

Biotarget 2017 May 25;1. Epub 2017 May 25.

University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.21037/biotarget.2017.05.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448778PMC

New insights into MTORC1 amino acid sensing and activation.

Biotarget 2017 May 16;1. Epub 2017 May 16.

Life Sciences Institute and Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, USA.

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http://biotarget.amegroups.com/article/view/3650/4339
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http://dx.doi.org/10.21037/biotarget.2017.04.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110396PMC
May 2017
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