39 results match your criteria Bioresources and bioprocessing[Journal]

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Enzymatic characterization of a recombinant carbonyl reductase from sp. CCTCC M209061.

Bioresour Bioprocess 2017 28;4(1):39. Epub 2017 Aug 28.

Lab of Applied Biocatalysis, School of Food Science and Engineering, South China University of Technology, Guangzhou, 510640 Guangdong China.

Background: sp. CCTCC M209061 could catalyze carbonyl compounds to chiral alcohols following anti-Prelog rule with excellent enantioselectivity. Therefore, the enzymatic characterization of carbonyl reductase (CR) from sp. Read More

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http://dx.doi.org/10.1186/s40643-017-0169-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573764PMC
August 2017
5 Reads

Germ soak water as nutrient source to improve fermentation of corn grits from modified corn dry grind process.

Bioresour Bioprocess 2017 23;4(1):38. Epub 2017 Aug 23.

Department of Agricultural and Biological Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801 USA.

Corn fractionation in modified dry grind processes results in low fermentation efficiency of corn grits because of nutrient deficiency. This study investigated the use of nutrient-rich water from germ soaking to improve grits fermentation in the conventional dry grind and granular starch hydrolysis (GSH) processes. Comparison of germ soak water with the use of protease and external B-vitamin addition in improving grits fermentation was conducted. Read More

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http://dx.doi.org/10.1186/s40643-017-0170-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569144PMC
August 2017
10 Reads

Enhancing transglutaminase production of by iterative mutagenesis breeding with atmospheric and room-temperature plasma (ARTP).

Bioresour Bioprocess 2017 12;4(1):37. Epub 2017 Aug 12.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237 People's Republic of China.

Objectives: To improve the fermentation production of transglutaminase (TGase) from for applications in the food industry, the atmospheric and room-temperature plasma (ARTP) mutagenesis was applied to breed mutants with increased TGase production.

Results: After eight rounds of iterative ARTP mutagenesis, four genetically stable mutants, 5-V1, 6-V13, 2-V10, and 7-V12, were identified, which showed increased TGase production by 27, 24, 24, and 19%, respectively. The best mutant 5-V1 exhibited a maximum TGase activity of 5. Read More

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http://dx.doi.org/10.1186/s40643-017-0168-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554476PMC
August 2017
6 Reads

Photocontrolled reversible self-assembly of dodecamer nitrilase.

Bioresour Bioprocess 2017 4;4(1):36. Epub 2017 Aug 4.

State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai, China.

Background: Naturally photoswitchable proteins act as a powerful tool for the spatial and temporal control of biological processes by inducing the formation of a photodimerizer. In this study, a method for the precise and reversible inducible self-assembly of dodecamer nitrilase in vivo (in ) and in vitro (in a cell-free solution) was developed by means of the photoswitch-improved light-inducible dimer (iLID) system which could induce protein-protein dimerization.

Results: Nitrilase was fused with the photoswitch protein AsLOV2-SsrA to achieve the photocontrolled self-assembly of dodecamer nitrilase. Read More

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http://dx.doi.org/10.1186/s40643-017-0167-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544783PMC
August 2017
9 Reads

Application of methanol and sweet potato vine hydrolysate as enhancers of citric acid production by .

Bioresour Bioprocess 2017 27;4(1):35. Epub 2017 Jul 27.

College of Life Sciences, Zhejiang University, Hangzhou, 310058 Zhejiang People's Republic of China.

Background: Agricultural waste is as an alternative low-cost carbon source or beneficial additives which catch most people's eyes. In addition, methanol and sweet potato vine hydrolysate (SVH) have been reported as the efficient enhancers of fermentation according to some reports. The objective of the present study was to confirm SVH as an efficient additive in CA production and explore the synergistic effects of methanol and SVH in fermentation reactions. Read More

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http://dx.doi.org/10.1186/s40643-017-0166-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532408PMC
July 2017
5 Reads

Recent progress on deep eutectic solvents in biocatalysis.

Bioresour Bioprocess 2017 21;4(1):34. Epub 2017 Jul 21.

Laboratory of Applied Biocatalysis, School of Food Sciences and Engineering, South China University of Technology, Guangzhou, 510640 China.

Deep eutectic solvents (DESs) are eutectic mixtures of salts and hydrogen bond donors with melting points low enough to be used as solvents. DESs have proved to be a good alternative to traditional organic solvents and ionic liquids (ILs) in many biocatalytic processes. Apart from the benign characteristics similar to those of ILs (e. Read More

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http://dx.doi.org/10.1186/s40643-017-0165-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522511PMC
July 2017
16 Reads

Microbial transformation of artemisinin by .

Bioresour Bioprocess 2017 17;4(1):33. Epub 2017 Jul 17.

School of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, 541004 People's Republic of China.

Background: Artemisinin () and its derivatives are now being widely used as antimalarial drugs, and they also exhibited good antitumor activities. So there has been much interest in the structural modification of artemisinin and its derivatives because of their effective bioactivities. The microbial transformation is a promising route to obtain artemisinin derivatives. Read More

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http://dx.doi.org/10.1186/s40643-017-0164-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514170PMC
July 2017
4 Reads

Mycoremediation potential of species for heavy metals: a review.

Bioresour Bioprocess 2017 10;4(1):32. Epub 2017 Jul 10.

Department of Biotechnology, Manav Rachna International University, Sector 43, Faridabad, 121004 India.

Mycoremediation is one of the biotechniques that recruits fungi to remove toxic pollutants from environment in an efficient and economical manner. Mushrooms, macro-fungi, are among the nature's most important mycoremediators. species (also called oyster mushrooms) are considered to be the most popular and widely cultivated varieties worldwide and this might be attributed to their low production cost and higher yields. Read More

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http://bioresourcesbioprocessing.springeropen.com/articles/1
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http://dx.doi.org/10.1186/s40643-017-0162-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504202PMC
July 2017
7 Reads

Study on community structure of microbial consortium for the degradation of viscose fiber wastewater.

Bioresour Bioprocess 2017 10;4(1):31. Epub 2017 Jul 10.

Key Laboratory of Industrial Fermentation Microbiology, (Ministry of Education), Tianjin University of Science & Technology, Tianjin, 300457 People's Republic of China.

Background: Enrichment culture was applied to obtain microbial consortium from activated sludge samples collected from biodegradation system, a chemical fiber plant in Hebei Province, China. Bacterial composition and community dynamic variation were assessed employing denaturing gradient gel electrophoresis fingerprinting technology based on amplified 16S rRNA genes in the entire process of enrichment culture for viscose fiber wastewater.

Results: Four bacteria named as VF01, VF02, VF03, and VF04 were isolated from the microbial consortium adopting the spray-plate method. Read More

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http://dx.doi.org/10.1186/s40643-017-0159-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502227PMC
July 2017
9 Reads

Comparative evaluation of wastewater-treatment microbial fuel cells in terms of organics removal, waste-sludge production, and electricity generation.

Bioresour Bioprocess 2017 6;4(1):30. Epub 2017 Jul 6.

School of Life Science, Tokyo University of Pharmacy and Life Sciences, Tokyo, 192-0392 Japan.

Microbial fuel cells (MFCs) are devices that exploit living microbes for electricity generation coupled to organics degradation. MFCs are expected to be applied to energy-saving wastewater treatment (WWT) as alternatives to activated-sludge reactors (ASRs). Although extensive laboratory studies have been performed to develop technologies for WWT-MFCs, limited information is available for comparative evaluation of MFCs and ASRs in terms of organics removal and waste-sludge production. Read More

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http://dx.doi.org/10.1186/s40643-017-0163-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500675PMC
July 2017
5 Reads

Biochemical properties of a new thermo- and solvent-stable xylanase recovered using three phase partitioning from the extract of strain SJ3.

Bioresour Bioprocess 2017 5;4(1):29. Epub 2017 Jul 5.

Laboratory of Applied Microbiology, Faculty of Nature Science and Life, University of Bejaia, 06000 Bejaia, Algeria.

The present study investigates the production and partial biochemical characterization of an extracellular thermostable xylanase from the strain SJ3 newly recovered from Algerian soil using three phase partitioning (TPP). The maximum xylanase activity recorded after 2 days of incubation at 37 °C was 20.24 U/ml in the presence of oat spelt xylan. Read More

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http://dx.doi.org/10.1186/s40643-017-0161-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498614PMC
July 2017
13 Reads

Microbial degradation of petrochemical waste-polycyclic aromatic hydrocarbons.

Authors:
M H Fulekar

Bioresour Bioprocess 2017 30;4(1):28. Epub 2017 Jun 30.

School of Environment and Sustainable Development, Central University of Gujarat, Sector 30, Gandhinagar, 382030 India.

Background: Petrochemical industry is one of the fastest growing industries. This industry has immense importance in the growth of economy and manufacture of large varieties of chemicals. The petrochemical industry is a hazardous group of industry generating hazardous waste containing organic and inorganic compounds. Read More

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http://dx.doi.org/10.1186/s40643-017-0158-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493705PMC

Lobster processing by-products as valuable bioresource of marine functional ingredients, nutraceuticals, and pharmaceuticals.

Bioresour Bioprocess 2017 22;4(1):27. Epub 2017 Jun 22.

Centre for Marine Bioproducts Development, Flinders University, Adelaide, Australia.

The worldwide annual production of lobster was 165,367 tons valued over $3.32 billion in 2004, but this figure rose up to 304,000 tons in 2012. Over half the volume of the worldwide lobster production has been processed to meet the rising global demand in diversified lobster products. Read More

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http://dx.doi.org/10.1186/s40643-017-0157-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487823PMC
June 2017
4 Reads

Detoxification of parthenium () and its metamorphosis into an organic fertilizer and biopesticide.

Bioresour Bioprocess 2017 15;4(1):26. Epub 2017 Jun 15.

Centre for Pollution Control & Environmental Engineering, Pondicherry University, Chinakalapet, Puducherry, 605 014 India.

Background: Vermicompost of the toxic and allelopathic weed parthenium () was explored for its possible use as an organic fertilizer. Replicated plant growth trials were conducted using four levels of parthenium vermicompost (0, 2.5, 3. Read More

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http://dx.doi.org/10.1186/s40643-017-0156-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487821PMC
June 2017
2 Reads

Beechwood carbohydrates for enzymatic synthesis of sustainable glycolipids.

Bioresour Bioprocess 2017 7;4(1):25. Epub 2017 Jun 7.

Institute of Process Engineering in Life Sciences, Section II: Technical Biology, Karlsruhe Institute of Technology (KIT), Engler-Bunte-Ring 3, 76131 Karlsruhe, Germany.

Moving away from crude oil to renewable resources for the production of a wide range of compounds is a challenge for future generations. To overcome this, the use of lignocellulose as substrate can contribute to drastically reduce the consumption of crude oil. In this study, sugars from lignocellulose were used as a starting material for the enzymatic synthesis of surface-active sugar esters. Read More

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http://dx.doi.org/10.1186/s40643-017-0155-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487819PMC
June 2017
5 Reads

Green synthesis of enzyme/metal-organic framework composites with high stability in protein denaturing solvents.

Bioresour Bioprocess 2017 19;4(1):24. Epub 2017 May 19.

Key Lab for Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing, 100084 China.

Objectives: Enzyme/metal-organic framework composites with high stability in protein denaturing solvents were reported in this study.

Results: Encapsulation of enzyme in metal-organic frameworks (MOFs) via co-precipitation process was realized, and the generality of the synthesis was validated by using cytochrome c, horseradish peroxidase, and lipase B as model enzymes. The stability of encapsulated enzyme was greatly increased after immobilization on MOFs. Read More

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http://dx.doi.org/10.1186/s40643-017-0154-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438438PMC
May 2017
55 Reads

Mineralization of a sulfonated textile dye Reactive Red 31 from simulated wastewater using pellets of .

Bioresour Bioprocess 2017 17;4(1):23. Epub 2017 May 17.

School of Environment and Sustainable Development, Central University of Gujarat, Gandhinagar, Gujarat 382030 India.

Background: Reactive Red 31, applied extensively in the commercial textile industry, is a hazardous and persistent azo dye compound often present in dye manufacturing and textile industrial effluents. strain was isolated from dye contaminated zones of Gujarat Industrial Development Corporation, Vatva, Ahmedabad, India. The decolorization potential was monitored by the decrease in maximum absorption of the dye using UV-visible spectroscopy. Read More

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http://dx.doi.org/10.1186/s40643-017-0153-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435774PMC
May 2017
13 Reads

Comprehensive reconstruction and evaluation of genome-scale metabolic model that accounts for 1243 ORFs.

Bioresour Bioprocess 2017 9;4(1):22. Epub 2017 May 9.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, No.130, Meilong Road, Shanghai, 200237 China.

Background: is one of the most important cell factories for production of industrial enzymes and heterogenous proteins. The genome-scale metabolic model of high quality is crucial for comprehensive understanding of the metabolism.

Methods: In this paper, we upgraded genome-scale metabolic model based on the combination of latest genome annotations and literatures. Read More

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http://dx.doi.org/10.1186/s40643-017-0152-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423920PMC
May 2017
3 Reads

Biofibres from biofuel industrial byproduct- seed hull.

Bioresour Bioprocess 2017 21;4(1):14. Epub 2017 Feb 21.

Department of Chemical Engineering, National Institute of Technology Karnataka, Surathkal, India.

Background: Biodiesel production using seeds results in large amount of unused seed hull. These seed hulls serve as a potential source for cellulose fibres which can be exploited as reinforcement in composites.

Methods: These seed hulls were processed using chlorination and alkaline extraction process in order to isolate cellulose fibres. Read More

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http://dx.doi.org/10.1186/s40643-017-0144-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320004PMC
February 2017
6 Reads

Efficient expression of sortase A from in and its enzymatic characterizations.

Bioresour Bioprocess 2017 18;4(1):13. Epub 2017 Feb 18.

The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, China.

Background: Sortase A (SrtA) is a transpeptidase found in , which is widely used in site-specific protein modification. However, SrtA was expressed in () in rather low level (ranging from several milligrams to 76.9 mg/L at most). Read More

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http://dx.doi.org/10.1186/s40643-017-0143-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316389PMC
February 2017
46 Reads

Techno-economic analysis of extraction-based separation systems for acetone, butanol, and ethanol recovery and purification.

Bioresour Bioprocess 2017 13;4(1):12. Epub 2017 Feb 13.

Control y Percepción Inteligente, Departamento de Ingeniería Eléctrica, Electrónica y Computación, Universidad Nacional de Colombia, Cra. 27 No. 64-60, Manizales, Colombia.

Background: Dual extraction, high-temperature extraction, mixture extraction, and oleyl alcohol extraction have been proposed in the literature for acetone, butanol, and ethanol (ABE) production. However, energy and economic evaluation under similar assumptions of extraction-based separation systems are necessary. Hence, the new process proposed in this work, direct steam distillation (DSD), for regeneration of high-boiling extractants was compared with several extraction-based separation systems. Read More

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http://dx.doi.org/10.1186/s40643-017-0142-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306422PMC
February 2017
40 Reads

Advances in industrial microbiome based on microbial consortium for biorefinery.

Bioresour Bioprocess 2017 8;4(1):11. Epub 2017 Feb 8.

School of Life Science and Biotechnology, Dalian University of Technology, Linggong Road 2, Dalian, 116024 Liaoning Province China.

One of the important targets of industrial biotechnology is using cheap biomass resources. The traditional strategy is microbial fermentations with single strain. However, cheap biomass normally contains so complex compositions and impurities that it is very difficult for single microorganism to utilize availably. Read More

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http://dx.doi.org/10.1186/s40643-017-0141-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306255PMC
February 2017
5 Reads

Changes of membrane fatty acids and proteins of treated with cinnamon oil and gamma irradiation.

Bioresour Bioprocess 2017 30;4(1):10. Epub 2017 Jan 30.

Department of Food Science, Ocean College, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou, 310014 China.

Background: In order to detect the antimicrobial mechanism of combined treatment of cinnamon oil and gamma irradiation (GI), the membrane fatty acids and proteins characteristics of () treated with cinnamon oil and GI, and the distribution of cinnamon oil in were observed in this study.

Results: The membrane lipid profile of was notably damaged by treatments of cinnamon oil and the combination of cinnamon oil and GI, with significantly fatty acids decrease in C14:0, C16:0, C16:1, C17:1, C18:1 ( < 0.05). Read More

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http://bioresourcesbioprocessing.springeropen.com/articles/1
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http://dx.doi.org/10.1186/s40643-017-0140-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283506PMC
January 2017
7 Reads

A food-grade expression system for d-psicose 3-epimerase production in using an alanine racemase-encoding selection marker.

Bioresour Bioprocess 2017 28;4(1). Epub 2017 Jan 28.

Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 People's Republic of China.

Background: Food-grade expression systems require that the resultant strains should only contain materials from food-safe microorganisms, and no antibiotic resistance marker can be utilized. To develop a food-grade expression system for d-psicose 3-epimerase production, we use an alanine racemase-encoding gene as selection marker in .

Results: In this study, the d-alanine racemase-encoding gene was deleted from the chromosome of 1A751 using Cre/ system to generate the food-grade host. Read More

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http://dx.doi.org/10.1186/s40643-017-0139-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5274643PMC
January 2017
5 Reads

An efficient multi-stage fermentation strategy for the production of microbial oil rich in arachidonic acid in .

Bioresour Bioprocess 2017 18;4(1). Epub 2017 Jan 18.

College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, No. 30 South Puzhu Road, Nanjing, 211816 People's Republic of China.

Background: Fungal morphology and aeration play a significant role in the growth process of . The production of microbial oil rich in arachidonic acid (ARA) in was enhanced by using a multi-stage fermentation strategy which combined fed-batch culture with precise control of aeration and agitation rates at proper times.

Results: The fermentation period was divided into four stages according to the cultivation characteristics of . Read More

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http://dx.doi.org/10.1186/s40643-017-0138-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243910PMC
January 2017
11 Reads

Recent updates on different methods of pretreatment of lignocellulosic feedstocks: a review.

Bioresour Bioprocess 2017 18;4(1). Epub 2017 Jan 18.

Bioconversion Technology Division, Sardar Patel Renewable Energy Research Institute, Vallabh Vidyanagar, Anand, 388 120 Gujarat India.

Lignocellulosic feedstock materials are the most abundant renewable bioresource material available on earth. It is primarily composed of cellulose, hemicellulose, and lignin, which are strongly associated with each other. Pretreatment processes are mainly involved in effective separation of these complex interlinked fractions and increase the accessibility of each individual component, thereby becoming an essential step in a broad range of applications particularly for biomass valorization. Read More

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http://dx.doi.org/10.1186/s40643-017-0137-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241333PMC
January 2017
4 Reads

Fungal pretreatment of raw digested piggery wastewater enhancing the survival of algae as biofuel feedstock.

Bioresour Bioprocess 2017 12;4(1). Epub 2017 Jan 12.

The Engineering Research Center for Biomass Conversion, Ministry of Education, Nanchang University, Nanchang, 330047 China.

Background: Understanding about the impact of white rot fungi on indigenous bacterial communities, NH and turbidity in digested piggery wastewater, will allow the optimization of wastewater treatment methods and its use as a feasible medium for algal growth. Here, the white rot fungi were inoculated into undiluted and unsterilized digested piggery wastewater under different temperatures and pH regimes in order to lower the pretreatment cost. Diversity and abundance of the bacterial communities in the pretreated wastewater were assessed by PCR-denaturing gradient gel electrophoresis coupled with 16S rDNA sequencing. Read More

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http://dx.doi.org/10.1186/s40643-016-0136-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236085PMC
January 2017
26 Reads

Hydrolysis of carotenoid esters from by the action of lipases from .

Bioresour Bioprocess 2017 6;4(1). Epub 2017 Jan 6.

Departamento de Ingeniería Química, Instituto Tecnológico de Celaya, Av. Tecnológico y A.G. Cubas s/n, 38010 Celaya, Gto Mexico.

The present study was conducted to evaluate the feasibility of enzymatic hydrolysis of carotenoid esters from using lipases from the yeast of , with the aim of obtaining free lutein. The optimal concentrations of seven nutrients, considering the production of lipases relative to biomass () as the response variable, were determined in flask fermentations. In addition, we studied the effect on hydrolysis of growing in the presence of the oleoresin of the marigold flower in flask and stirred tank. Read More

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http://dx.doi.org/10.1186/s40643-016-0131-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236077PMC
January 2017
5 Reads

Investigation of spiral-wound membrane modules for the cross-flow nanofiltration of fermentation broth obtained from a pilot plant fermentation reactor for the continuous production of lactic acid.

Bioresour Bioprocess 2017 4;4(1). Epub 2017 Jan 4.

Department of Bioengineering, Leibniz-Institute for Agricultural Engineering Potsdam-Bornim e.V., Max-Eyth-Allee 100, 14469 Potsdam, Brandenburg Germany.

Background: The separation performance of seven polymer membranes for the nanofiltration of sodium lactate in fermentation broth was investigated. Each module was introduced into the test stand, and the system curve was obtained by recording the permeate flow velocity at different pump head levels. Performance benchmarks were good permeate quality, as determined by high permeate flow velocity, high sodium lactic concentration, low ion impurity concentration, and low organic impurity concentration. Read More

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http://dx.doi.org/10.1186/s40643-016-0133-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236076PMC
January 2017

Online flow cytometry, an interesting investigation process for monitoring lipid accumulation, dimorphism, and cells' growth in the oleaginous yeast JMY 775.

Bioresour Bioprocess 2017 3;4(1). Epub 2017 Jan 3.

Unité de Bio-Industries, Passage des déportés, Université de Liège/Gembloux AGRO-BIO Tech, 2-5030 Gembloux, Belgium.

This study aims to understand and better control the main biological mechanisms and parameters modulating the various phenomena affecting JMY775 and its lipids accumulation. The results obtained in this study stress forward that the use of an original tool, consisting of coupling bioreactors to online flow cytometry, is highly efficient. Throughout 48 h of culturing, this emerging process allowed an online continuous observation of the effects of pH and/or aeration on the cell growth and dimorphism and lipid accumulation by . Read More

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http://dx.doi.org/10.1186/s40643-016-0132-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236074PMC
January 2017
4 Reads

Stereoselective biotransformation of racemic mandelic acid using immobilized laccase and (S)-mandelate dehydrogenase.

Bioresour Bioprocess 2017 3;4(1). Epub 2017 Jan 3.

Department of Bioengineering, Nanjing University of Science and Technology, Xiaolingwei 200, Nanjing, 210094 People's Republic of China.

Objectives: (S)-Mandelate dehydrogenase (SMDH) and laccase were immobilized on chitosan. The bi-enzymatic system with immobilized SMDH and immobilized laccase was taken to catalyze the stereoselective transformation of racemic mandelic acid and (R)-mandelic acid was obtained from its racemic mixture.

Results: Characteristics of the immobilized enzymes were valuated. Read More

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http://dx.doi.org/10.1186/s40643-016-0135-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236080PMC
January 2017
11 Reads

Dissolved oxygen control strategy for improvement of TL1-1 production in submerged fermentation by .

Bioresour Bioprocess 2017 2;4(1). Epub 2017 Jan 2.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Box 283#, Shanghai, 200237 People's Republic of China ; Shanghai Collaborative Innovation Center for Biomanufacturing Technology, 130 Meilong Road, Shanghai, 200237 People's Republic of China.

Background: 2,3-Dihydro-5-hydroxy-2-methylchromen-4-one (TL1-1) is a phenolic compound with significant anti-fungal and anti-cancer activities produced by (). However, studies have rarely been reported on the fermentation process of due to the urgent demand for its pharmaceutical researches and applications.

Results: In this work, the optimal fermentation medium for improved TL1-1 yield was first obtained in a shake flask. Read More

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http://dx.doi.org/10.1186/s40643-016-0134-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236084PMC
January 2017
5 Reads

Degradation study of lindane by novel strains sp. DAB-1Y and sp. DAB-1W.

Bioresour Bioprocess 2016 28;3(1):53. Epub 2016 Dec 28.

Department of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Sonepat, Haryana 131039 India.

Background: This study was carried out to isolate and characterize the bacterial strains from lindane-contaminated soil and they were also assessed for their lindane-degrading potential.

Methods: In this study the enrichment culture method was used for isolation of  lindane degrading bacterial isolates, in which the mineral salt medium (MSM) supplemented with different concentrations of lindane was used. Further, the screening for the potential lindane degrading isolates was done using the spray plate method and colorimetric dechlorinase enzyme assay. Read More

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http://bioresourcesbioprocessing.springeropen.com/articles/1
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http://dx.doi.org/10.1186/s40643-016-0130-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196013PMC
December 2016
11 Reads

Metabolic engineering of MG1 for enhanced production of ()-acetoin.

Bioresour Bioprocess 2016 28;3(1):52. Epub 2016 Nov 28.

State Key Laboratory of Bioreactor Engineering, Shanghai Collaborative Innovation Center for Biomanufacturing Technology, East China University of Science and Technology, Shanghai, 200237 China.

Background: Optically pure acetoin (AC) is an important platform chemical which has been widely used to synthesize novel optically active α-hydroxyketone derivatives and liquid crystal composites.

Results: In this study, C and A encoding -2,3-butanediol dehydrogenase (-2,3-BDH) and glycerol dehydrogenase (GDH), respectively, in MG1 were knocked out to block the conversion from AC to 2,3-butanediol (2,3-BD). The resulting strain MG14 was found to produce a large amount of optically pure ()-AC with a little 2,3-BD, indicating that another enzyme responsible for 2,3-BD formation except -2,3-BDH and GDH existed in the strain MG1. Read More

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http://dx.doi.org/10.1186/s40643-016-0128-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124605PMC
November 2016
7 Reads

Engineering a wild-type diploid strain for second-generation bioethanol production.

Bioresour Bioprocess 2016 24;3(1):51. Epub 2016 Nov 24.

State Key Laboratory of Microbial Technology, Shandong University, Shan Da Nan Road 27, Jinan, 250100 China.

Background: The cost-effective production of second-generation bioethanol, which is made from lignocellulosic materials, has to face the following two problems: co-fermenting xylose with glucose and enhancing the strain's tolerance to lignocellulosic inhibitors. Based on our previous study, the wild-type diploid strain BSIF with robustness and good xylose metabolism genetic background was used as a chassis for constructing efficient xylose-fermenting industrial strains. The performance of the resulting strains in the fermentation of media with sugars and hydrolysates was investigated. Read More

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http://dx.doi.org/10.1186/s40643-016-0126-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122614PMC
November 2016
15 Reads

Electricity generation from rice bran in microbial fuel cells.

Bioresour Bioprocess 2016 23;3(1):50. Epub 2016 Nov 23.

School of Life Science, Tokyo University of Pharmacy and Life Sciences, Tokyo, 192-0392 Japan.

Background: Rice bran is a by-product of the rice milling process and mostly discarded in Japan. Although many studies have shown that microbial fuel cells (MFCs) are able to generate electricity from organic wastes, limited studies have examined MFCs for generating electricity from rice bran.

Findings: Laboratory-scale single-chamber MFCs were inoculated with paddy field soil and supplied with rice bran for examining electricity generation. Read More

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http://bioresourcesbioprocessing.springeropen.com/articles/1
Publisher Site
http://dx.doi.org/10.1186/s40643-016-0129-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120057PMC
November 2016
7 Reads

Penicillin acylase-catalyzed synthesis of -bromoacetyl-7-aminocephalosporanic acid, the key intermediate for the production of cefathiamidine.

Bioresour Bioprocess 2016 19;3(1):49. Epub 2016 Nov 19.

School of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou, 510640 China.

Background: Enzymatic approaches have become promising alternatives to chemical methods for the production of semi-synthetic β-lactam antibiotics. In this work, enzymatic synthesis of -bromoacetyl-7-aminocephalosporanic acid (-bromoacetyl-7-ACA), the key intermediate for the production of cefathiamidine, was reported for the first time.

Results: Of the immobilized penicillin acylases (PAs) tested, PGA-750 was the best biocatalyst. Read More

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http://dx.doi.org/10.1186/s40643-016-0127-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116309PMC
November 2016
2 Reads

In silico profiling of cell growth and succinate production in NZN111.

Bioresour Bioprocess 2016 15;3(1):48. Epub 2016 Nov 15.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China ; Shanghai Collaborative Innovation Center for Biomanufacturing Technology (SCICBT), Shanghai, China.

Background: Succinic acid is a valuable product due to its wide-ranging utilities. To improve succinate production and reduce by-products formation, NZN111 was constructed by insertional inactivation of lactate dehydrogenase (LDH) and pyruvate formate lyase (PFL) encoded by the genes and , respectively. However, this double-deletion mutant is incapable of anaerobically growing on glucose in rich or minimal medium even with acetate supplementation. Read More

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http://dx.doi.org/10.1186/s40643-016-0125-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110578PMC
November 2016
6 Reads

Combined C-assisted metabolomics and metabolic flux analysis reveals the impacts of glutamate on the central metabolism of high β-galactosidase-producing .

Bioresour Bioprocess 2016 2;3(1):47. Epub 2016 Nov 2.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, No.130, Meilong Road, Shanghai, 200237 China.

Background: is a popular recombinant protein expression system for its accessibility of efficient gene manipulation and high protein production. Sufficient supply of precursors, energy, and redox cofactors is crucial for high recombinant protein production. In our present work, we found that the addition of glutamate improved the recombinant β-galactosidase (β-gal) production by G1HL. Read More

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http://dx.doi.org/10.1186/s40643-016-0124-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093185PMC
November 2016
8 Reads
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