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Curr Rheumatol Rev 2022 Aug 17. Epub 2022 Aug 17.

Institute for Health Sciences from Federal University of Bahia, Salvador, Bahia, Brazil.

Background: Few studies have described lymphocytic interstitial pneumonia (LIP) in Sjögren's syndrome (SS). We aimed to analyze the clinical, therapeutic, and outcome of patients with SS and LIP.

Methods: We searched for articles in PubMed/MEDLINE, LILACS, SciELO, and Cochrane from 1966 to 2020, in English, Spanish, French, Chinese, and Japanese literature had an English summary about LIP and SS. Read More

New Phytol 2001 Oct;152(1):151-158

Mycorrhiza Research Group, School of Science Food & Horticulture, University of Western Sydney, Parramatta Campus, Locked Bag 1797, PENRITH SOUTH DC, NSW 1797, Australia.

•  Genes for ligninolytic enzymes, normally associated with white-rot fungi, are shown to be widespread in a broad taxonomic range of ectomycorrhizal (ECM) fungi. •  ECM fungi were screened for lignin peroxidase (LiP) and manganese peroxidase (MnP) genes by PCR using primers specific for known isozymes in the white-rot fungus Phanerochaete chrysosporium, with DNA sequencing used to confirm the identity of the amplified fragments. •  Genes for LiPs were detected in ECM fungi representing the orders Agaricales, Aphyllophorales, Boletales, Cantharellales, Hymenochaetales, Sclerodermatales, Stereales and Thelephorales. Read More

Microbiol Spectr 2022 Aug 16:e0272421. Epub 2022 Aug 16.

Department of Microbiology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt.

Vaginal candidiasis is a medical condition characterized by the overgrowth of spp. in the vaginal cavity with complex recurrent pathogenicity as well as tolerance to antifungal therapy and hence is awaiting more safe and effective treatments. This work aimed to assess the potential antifungal activity of galloylquinic acid compounds (GQAs) from Copaifera lucens leaves against vaginal Candida albicans. Read More

J Oral Maxillofac Pathol 2022 Apr-Jun;26(2):283. Epub 2022 Jun 28.

Department of Oral Pathology and Microbiology, Postgraduate Institute of Dental Sciences, Rohtak, Haryana, India.

Background: Mucoceles are mucus-filled cavities and are broadly of two types: mucus retention cysts and mucus extravasation phenomenon. A wide variety of histological features have been documented in the literature. The present study was an attempt to study these histological features: papillary synovial metaplasia-like changes (PSM-like changes) in particular. Read More

Front Oncol 2022 28;12:934862. Epub 2022 Jul 28.

Department of Radiation Oncology, Qilu Hospital of Shandong University, Jinan, China.

Background: Ectopic adrenal tissue is rare in adults, with an incidence of only about 1%. We report a rare case of ectopic adrenocortical adenoma in the left renal sinus.

Case Preentation: A 57-year-old woman was admitted to the Department of Urology due to "a left kidney tumor" on physical examination. Read More

Clin Case Rep 2022 Aug 9;10(8):e6240. Epub 2022 Aug 9.

Kathmandu Medical College Teaching Hospital Kathmandu Nepal.

Macrocheilia, as an initial manifestation of leprosy, is uncommon. We present a case of a 50-year-old female, with lower lip swelling, initially diagnosed as Cheilitis Granulomatosa Miescher. Unresponsiveness to local intralesional corticosteroids necessitated further evaluation. Read More

Clin Case Rep 2022 Aug 8;10(8):e6191. Epub 2022 Aug 8.

Skin Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

The lichen planus (LP) is an inflammatory and immune-mediated disorder that can affect the hair, mucous membranes, nails, and skin. Lichen planus rarely affects the lips. In cases of lip involvement, it presents as radiated streaks, lace-like papules, and erosions. Read More

Case Rep Dent 2022 2;2022:6121315. Epub 2022 Aug 2.

Division of Oral and Maxillofacial Surgery, Department of Surgery Related, Kobe University Graduate School of Medicine, Kobe, Japan.

Actinomycosis is usually a chronic infectious disease caused by species, which are anaerobic Gram-positive bacteria that normally colonize the human oral cavity and digestive and urogenital tracts. Although this lesion often occurs on soft tissue around the mandible, cases localized in the lip are very uncommon. We encountered a patient with actinomycosis in the lower lip. Read More

Mod Rheumatol Case Rep 2022 Aug 11. Epub 2022 Aug 11.

Department of Paediatrics, Nippon Medical School, Tokyo, Japan.

In paediatric, primary Sjögren's syndrome, the initial symptoms manifest systemically, such as fever, general fatigue, and lymphadenopathy, rather than sicca symptoms. Most children with primary Sjögren's syndrome have autoantibodies, such as antinuclear, anti-Ro/SS-A, and/or anti-La/SS-B antibodies; however, some patients are seronegative. Similar to paediatric patiantis with primary Sjögren's syndrome, those with Takayasu arteritis initially only present constitutional symptoms, making it difficult to suspect, unless characteristic features are present. Read More

Ann Dermatol 2022 Aug;34(4):291-296

Department of Stomatology, Public Health and Forensic Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

Focal dermal hypoplasia (FDH), also known as Goltz syndrome, consists of an unusual genodermatosis that affects tissues of ectodermal and mesodermal origin and various organs and systems, especially skin, bones, eyes, and oral cavity. While systemic manifestations of FDH have been well documented, the oral manifestations have not been extensively discussed. We present a 22-year-old female patient with history of FDH that showed a variety of systemic and oral manifestations. Read More

Am J Pathol 2022 Aug 7. Epub 2022 Aug 7.

Departments of Genetics, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, 35294, USA; Pathology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, 35294, USA; Dermatology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, 35294, USA. Electronic address:

Mitochondrial dysfunction is one of the hallmarks of aging. Changes in sebaceous gland function and sebum production have been reported during aging. Here we report the direct effects of mitochondrial dysfunction on sebaceous gland morphology and function. Read More

Rev Assoc Med Bras (1992) 2022 Jul;68(7):877-878

Lusiada University Centre, Department of Dermatology - Santos (SP), Brazil.

Sao Paulo Med J 2022 Aug 8. Epub 2022 Aug 8.

DDS, PhD. Associate Professor, Department of Surgery, Stomatology, Pathology and Radiology, Faculdade de Odontologia de Bauru (FOB), Universidade de Sao Paulo (USP), Bauru (SP), Brazil.

Background: There is a need for studies that correlate the severity of oral mucositis (OM) with chemotherapy protocols, transient myelosuppression and oral health.

Objective: To analyze the severity of OM among individuals with solid tumors during hospitalization and its correlation with the type of chemotherapy, myelosuppression and oral health condition.

Design And Setting: Retrospective study at a public hospital in Bauru, state of São Paulo, Brazil, that is a regional referral center. Read More

JAAD Case Rep 2022 Aug 2;26:101-103. Epub 2022 Jul 2.

Department of Dermatology, Saint-Louis Hospital, Assistances Publiques des Hôpitaux de Paris, Paris, France.

Clin Cosmet Investig Dermatol 2022 1;15:1475-1483. Epub 2022 Aug 1.

Department of Otolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong, People's Republic of China.

Purpose: The clinical and pathological data of patients with rhinofacial ulcers were retrospectively reviewed and analyzed to lay the foundation for standardized clinical treatment.

Patients And Methods: We retrospectively analyzed the clinical data, etiology, pathological features, treatment methods, and prognosis of 243 patients with rhinofacial ulcers treated in the Departments of Otorhinolaryngology and Dermatology at six hospitals in Shandong Province, China from July 2014 to October 2021. The clinical characteristics and treatment methods of the rhinofacial ulcers were summarized to provide a basis for standardizing patients' diagnosis and treatment. Read More

BMC Neurol 2022 Aug 5;22(1):294. Epub 2022 Aug 5.

Department of Neurology, Chonnam National University Medical School and Hospital, 42 Jebong-ro, Dong-gu, Gwangju, 58128, South Korea.

Background: Trigeminal neuropathy is characterized by numbness in the region innervated by the trigeminal nerves, with or without neuropathic weakness in the muscles of mastication. Trigeminal neuritis is a form of trigeminal neuropathy in which the lesion is caused by an inflammation. Herein, we report a patient with trigeminal neuritis due to central nervous system (CNS) involvement of herpes labialis (HL) infection, which was successfully treated with anti-viral and anti-inflammatory agents. Read More

J Control Release 2022 Aug 3;349:796-811. Epub 2022 Aug 3.

Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, USA. Electronic address:

We describe a role of CD44-mediated signaling during host-defense against tuberculosis (TB) using a mouse model of TB and studies in M. tuberculosis (Mtb) infected human macrophage (MФ). Liposomes targeting CD44 using thioaptamers (CD44TA-LIP) were designed and tested as new vaccines to boost host immunity in TB. Read More

Spec Care Dentist 2022 Aug 1. Epub 2022 Aug 1.

Department of Social and Preventive Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Aims: To synthesize the oral alterations observed in children with microcephaly associated with congenital Zika virus syndrome (CZS); and to compare the oral alterations of these children to a normotypic healthy controls.

Methods And Results: A search was performed in six electronic databases. Observational studies published that reported oral alterations in children with CZS were selected. Read More

Cleft Palate Craniofac J 2022 Aug 1:10556656221104027. Epub 2022 Aug 1.

Department of Surgery, 5228University of Wisconsin Madison, Madison, WI, USA.

To determine the prevalence of laryngeal pathology in children presenting with cleft palate with or without cleft lip (CP ± L) who underwent nasoendoscopy to assess palatal function. A secondary aim was to determine the relationship between patient demographics, resonance, articulation, and prevalence of laryngeal pathology in this population.

Retrospective, observational cohort study. Read More

Pan Afr Med J 2022 11;42:24. Epub 2022 May 11.

Maxillo-Facial Surgery Department, University Hospital Center Mohammed VI, Marrakech, Morocco.

Benign schwannomas are uncommon and their intraosseous location is even rarer counting for less than 1% of all benign primary bone tumors. They exceptionally occur in the oral cavity with the tongue being the most common site of involvement. We report here a case of intramandibular schwannoma derived from the inferior alveolar nerve, in a 57-year-old patient with a 3 months history of inferior left lip paresthesia. Read More

OTO Open 2022 Jul-Sep;6(3):2473974X221116107. Epub 2022 Jul 25.

Department of Otolaryngology-Head and Neck Surgery, NYU Langone Health, New York, New York, USA.

Objective: Previous studies have questioned the safety and efficacy of minor salivary gland biopsy in the diagnosis of Sjögren's syndrome, citing complications and difficulty of pathologic evaluation. This study aims to determine the rate of biopsy specimen adequacy and the risk of complications after minor salivary gland biopsy.

Study Design: Case series. Read More

Wiad Lek 2022 ;75(6):1453-1458

BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.

Objective: The aim: To conduct a prospective clinical study to assess the prevalence, structure, risk factors and features of clinical manifestations of precancerous diseases of oral mucosa and red lip in Kyiv residents and to analyze opportunities to improve the quality of their primary diagnosis.

Patients And Methods: Materials and methods: The examination of 423 patients with precancerous diseases of oral mucosa and red lip included clarification of the main complaints and anamnesis of the disease, objective assessment of the state of oral mucosa and red border of the lips according to visual, stomatoscopic, luminescent analysis, cyto-, histological studies.

Results: Results: Attention is drawn to the prevalence among precancerous diseases of patients with leukoplakia - 41. Read More

Virol J 2022 Jul 29;19(1):127. Epub 2022 Jul 29.

College of Information and Communication Technologies (CoICT), University of Dar Es Salaam, 14113, Dar es Salaam, Tanzania.

Background: HPV (human papillomavirus) is an important cause of cervical cancer. Cervical-vaginal infection with pathogens, such as herpes simplex virus (HSV), bacterial vaginosis Trichomonas vaginalis and vaginal candidiasis could be a cofactor. This study aimed to assess the relationship between vaginal infection with HPV genotype and cytology test results and analyze the relationship between vaginal and HPV infections and cervical cancer. Read More

J Med Case Rep 2022 Jul 28;16(1):306. Epub 2022 Jul 28.

Department of Pediatrics, Pediatric Genetics, Hacettepe University Medical Faculty, Ankara, Turkey.

Background: Xeroderma pigmentosum is an extremely serious genetic disorder defined by sensitivity to sunlight, resulting in sunburn and pigment changes. If patients are not completely protected from ultraviolet radiation, xeroderma pigmentosum is characterized by a greatly increased risk of sunlight-induced cutaneous neoplasms. There is no standard therapy for skin cancer of xeroderma pigmentosum. Read More

J Cancer Res Ther 2022 Apr-Jun;18(3):765-769

Department of Oral and Maxillofacial Surgery, Konaseema Institute of Dental Sciences, Amalapuram, Andhra Pradesh, India.

Minor salivary gland neoplasms constitute up to approximately 25% of all salivary gland tumors. The incidence of malignancy of these tumors is slightly greater than half. Basal cell adenocarcinoma (BCAC) is a rare salivary gland malignancy that occurs most commonly in the parotid gland. Read More

Plants (Basel) 2022 Jul 14;11(14). Epub 2022 Jul 14.

Cassava Program, Crops for Nutrition and Health, International Center for Tropical Agriculture (CIAT), The Americas Hub, Km 17 Recta Cali-Palmira, Cali 763537, Colombia.

Cassava frogskin disease (CFSD) is a graft-transmissible disease of cassava reported for the first time in the 1970s, in Colombia. The disease is characterized by the formation of longitudinal lip-like fissures on the peel of the cassava storage roots and a progressive reduction in fresh weight and starch content. Since its first report, different pathogens have been identified in CFSD-affected plants and improved sequencing technologies have unraveled complex mixed infections building up in plants with severe root symptoms. Read More

Molecules 2022 Jul 20;27(14). Epub 2022 Jul 20.

Key Laboratory of Coarse Cereal Processing, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.

Cell surface thiols can be targeted by thiol-reactive groups of various materials such as peptides, nanoparticles, and polymers. Here, we used the maleimide group, which can rapidly and covalently conjugate with thiol groups, to prepare surface-modified liposomes (M-Lip) that prolong retention of doxorubicin (Dox) at tumor sites, enhancing its efficacy. Surface modification with the maleimide moiety had no effect on the drug loading efficiency or drug release properties. Read More

Dent J (Basel) 2022 Jul 5;10(7). Epub 2022 Jul 5.

The Iowa Institute for Oral Health Research, College of Dentistry, University of Iowa, Iowa City, IA 52242, USA.

Individuals with orofacial clefting (OFC) have a higher prevalence of tooth agenesis (TA) overall. Neither the precise etiology of TA, nor whether TA occurs in patterns that differ by gender or cleft type is yet known. This meta-analysis aims to identify the spectrum of tooth agenesis patterns in subjects with non-syndromic OFC and controls using the Tooth Agenesis Code (TAC) program. Read More

Cleft Palate Craniofac J 2022 Jul 25:10556656221116005. Epub 2022 Jul 25.

Division of Plastic and Reconstructive Surgery, 12223Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Midface hypoplasia (MFH) is a long-term sequela of cleft lip and palate repair, and is poorly understood. No study has examined the aggregate data on sagittal growth restriction of the midface following repair of the lip, but not palate, in these patients.

A systematic review of 3780 articles was performed. Read More

Eur J Dermatol 2022 04;32(2):287-289

Department of Dermatology, Iwate Medical University School of Medicine, Yahaba-cho, Japan