918 results match your criteria Biopsy Fine Needle Neck Mass


Risk of thyroid carcinoma in patients treated surgically with assumed benign cytology in Riyadh, Saudi Arabia.

Acta Otorhinolaryngol Ital 2022 Jun;42(3):237-242

Department of Otolaryngology, Head and Neck Surgery, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Objectives: This study aimed to report the rate of thyroid malignancy in benign fine-needle aspirations (Bethesda II) at King Abdulaziz Medical City and evaluate the factors that affect false-negative outcomes of FNA.

Methods: All patients referred for thyroidectomy from 2009 to 2019 were reviewed (n = 1968). Only patients with a benign FNA, corresponding to the Bethesda II, were included (n = 384). Read More

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Proposal of Diagnostic Approach of Periodontal Primary Non Hodgkin Lymphoma of Bone with Flow Cytometry as an Essential Diagnostic Component.

Head Neck Pathol 2022 Jul 8. Epub 2022 Jul 8.

Department of Pathology, The University of Texas Medical Branch, Galveston, TX, 77555, USA.

Background: Primary bone lymphoma is a rare type of lymphoid neoplasm with favorable prognosis, where Primary Non Hodgkin Lymphoma of bone (PB-NHL) is most common with the subtype. Amongst PB-NHL, diffuse large Bcell lymphoma represents the majority of cases. The mandible is a very uncommon site of involvement, presenting as a painful bone mass with high suspicion of osteomyelitis. Read More

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Ectopic Papillary Thyroid Carcinoma Presenting as Right Lateral Neck Mass: A Case Report.

J ASEAN Fed Endocr Soc 2022 20;37(1):103-106. Epub 2022 Apr 20.

Department of Pathology, College of Medicine, University of the Philippines Manila, Metro Manila, Philippines.

A lateral neck mass can be the initial presentation of a papillary thyroid carcinoma. A 24-year-old female presented with a 2.0 x 2. Read More

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An Adult Female Presenting With "Scrofula-Tubercular Lymphadenitis" a Rare Encounter: A Case Report.

Cureus 2022 Jun 4;14(6):e25650. Epub 2022 Jun 4.

Department of Internal Medicine, Mount Sinai Hospital, Chicago, USA.

Cervical lymphadenitis is the most common extra-pulmonary manifestation of tuberculosis (TB). Usually, presenting with a neck mass with minimal systemic symptoms is a diagnostic challenge for physicians. Diagnosis is made by combining clinical features, microscopic and radiological imaging, and fine-needle aspiration biopsy. Read More

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Middle thyroid vein tumor thrombus in metastatic papillary thyroid microcarcinoma: A case report and review of literature.

World J Clin Cases 2022 Apr;10(10):3213-3221

Department of Otorhinolaryngology Head and Neck Surgery, Gansu Provincial Hospital, Lanzhou 730000, Gansu Province, China.

Background: Although papillary thyroid microcarcinoma (PTMC) is not considered a threatening tumor, in some cases, it can be aggressive. Metastatic thrombosis of papillary thyroid carcinoma, follicular thyroid carcinoma, Hürthle cell carcinoma, poorly differentiated thyroid carcinoma and anaplastic thyroid carcinoma have been reported in the literature, but there have been no reports about PTMC.

Case Summary: A 45-year-old woman presented with a thyroid mass and thrombosis in a middle thyroid vein during a physical examination. Read More

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Papillary thyroid microcarcinoma with contralateral lymphatic skip metastasis and breast cancer: A case report.

World J Clin Cases 2022 Apr;10(11):3609-3614

Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

Background: The recognized pattern of cervical lymph node metastasis (CLNM) of papillary thyroid carcinoma involves a stepwise route. Contralateral lymph node skip metastasis is very rare. In addition, the patient in our case report also suffered from a breast carcinoma accompanied by left supraclavicular lymphadenopathy, which made it difficult to distinguish the origin of the CLNM. Read More

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Papillary Thyroid Carcinoma with Nodular Fasciitis-Like Stroma in a 28-Year-Old Patient.

Iran J Pathol 2022 8;17(2):225-228. Epub 2022 Mar 8.

Department of Otolaryngology-Head and Neck Surgery, Otorhinolaryngology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Papillary thyroid carcinoma (PTC) is considered as a relatively common type of malignancy showing a wide morphologic spectrum. Different variants of this tumor have been reported. Among PTC variants, PTC with nodular fasciitis-like stroma (PTCFLS) is rare. Read More

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A case of primary histiocytic sarcoma arising from a neck lymph node.

Ear Nose Throat J 2022 Apr 20:1455613221097200. Epub 2022 Apr 20.

Department of Otolaryngology-Head and Neck Surgery, 38051Asahikawa Medical University, Asahikawa, Japan.

Histiocytic sarcoma (HS) is an aggressive and rare hematological malignancy. Its treatment has not been established, and most patients die within 2 years of diagnosis. Resection can provide a favorable prognosis for solitary lesions. Read More

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Modern Approach to the Neck Mass.

Surg Clin North Am 2022 Apr;102(2S):e1-e6

Department of Otolaryngology - Head and Neck Surgery, University of Colorado School of Medicine, Aurora, CO, USA. Electronic address:

Neck mass is a common first sign of malignancy in adult patients. Timely diagnosis can prevent disease progression. Initial evaluation of a neck mass includes creating a plan for obtaining further diagnostic information such as through imaging and tissue diagnosis. Read More

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Clinicopathological and Molecular Features of Secondary Cancer (Metastasis) to the Thyroid and Advances in Management.

Int J Mol Sci 2022 Mar 17;23(6). Epub 2022 Mar 17.

Cancer Molecular Pathology, School of Medicine and Dentistry, Menzies Health Institute Queensland, Griffith University, Gold Coast 4222, Australia.

Secondary tumours to the thyroid gland are uncommon and often incidentally discovered on imaging. Symptomatic patients often present with a neck mass. Collision tumours of secondary tumours and primary thyroid neoplasms do occur. Read More

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Oncocytoid Variant of High-Grade Salivary Duct Carcinoma: A Potential Diagnostic Pitfall. A Report on Two Patients.

Head Neck Pathol 2022 Mar 7. Epub 2022 Mar 7.

Department of Pathology, Icahn School of Medicine at Mount Sinai, 1468 Madison Avenue, New York, NY, 10029, USA.

Salivary duct carcinoma (SDC) is an uncommon and aggressive salivary malignancy. The oncocytoid variant of salivary duct carcinoma (OSDC) has only been reported in the English literature once before. Here we detail two new patients. Read More

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A 34-Year-Old Man With a Neck Mass.

Chest 2022 03;161(3):e145-e148

Department of Medicine, University of Malawi College of Medicine, Blantyre, Malawi; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, England. Electronic address:

Case Presentation: A 34-year-old man presented to Queen Elizabeth Central Hospital in Blantyre, Malawi with multiple enlarged right cervical lymph nodes. He had no associated constitutional symptoms. Fine-needle aspirate (FNA) of one of the lymph nodes was negative for acid-fast bacilli (AFB) by smear microscopy. Read More

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The Role of Anatomical Imaging and Intraoperative Neuromonitoring (IONM) for Successful Prediction of a Nonrecurrent Laryngeal Nerve.

Case Rep Surg 2022 21;2022:3147824. Epub 2022 Feb 21.

Department of Otolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.

A nonrecurrent laryngeal nerve (NRLN) is a rare anatomical variant of laryngeal nerves that branches directly from the vagus nerve. The anatomical abnormality makes it difficult to identify the NRLN and results in high incidence of accidental nerve injury during surgery. A 76-year-old woman complained of swelling in the right side of her neck and visited our university hospital for further examination. Read More

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February 2022

Coexistent Rosai Dorfman disease and Langerhans cell histiocytosis in an Orbital mass: A Case Report.

Eur J Ophthalmol 2022 Mar 1:11206721221083727. Epub 2022 Mar 1.

76300Guru Nanak Eye Centre, 28862Maulana Azad Medical College, New Delhi, India.

Introduction: Rosai Dorfman disease (RDD) is a rare benign histiocytic proliferative disorder of lymph node sinuses. Langerhans cell histiocytosis (LCH) is a solitary or multisystem clonal proliferation of abnormal dendritic cells (Langerhans cells) with varied presentations. The co-occurrence of these two entities is quite rare. Read More

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Excising Parotid Benign Mass With a Minimal Incision.

Cureus 2022 Feb 19;14(2):e22382. Epub 2022 Feb 19.

Otolaryngology - Head and Neck Surgery, King Saud Hospital, Qassim, SAU.

We report a case of a 30-year-old man who presented with a one-year history of a right-sided parotid mass that was asymptomatic but slowly increasing in size. On examination, there was a 2 × 2 cm superficial, soft, painless, and mobile mass in the right parotid region. Computed tomography revealed a benign mass in the right parotid tail measuring 2 × 3 cm, and a fine needle aspiration biopsy revealed a Warthin's tumor. Read More

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February 2022

Thyroid Follicular Cell-derived Carcinomas in a Background of Multiple Adenomatous Nodules Leading to a Diagnosis of Hamartoma Tumor Syndrome in an Adult Patient With a Novel Mutation.

Anticancer Res 2022 Mar;42(3):1481-1485

Department of Pathology and Laboratory Medicine, Kaiser Permanente Sacramento Medical Center, Sacramento, CA, U.S.A.

Background: Phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome (PHTS) is a complex disorder. Carriers develop hamartomatous tumors, with an increased risk for developing malignant tumors in multiple organs. Surveillance to facilitate the early detection and treatment of malignancies is extremely important. Read More

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Single fiber reflectance spectroscopy for pancreatic cancer detection during endoscopic ultrasound guided fine needle biopsy: a prospective cohort study.

Int J Med Sci 2022 1;19(2):205-212. Epub 2022 Jan 1.

Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.

This study aimed to determine the ability of single fiber reflectance (SFR) spectroscopy incorporated in endoscopic ultrasound fine needle biopsy (EUS-FNB) procedures in the pancreas to distinguish benign and malignant pancreatic tissue in patient with pancreatic masses suspected for malignancy. This study was designed as a prospective observational single center study and included consecutive adult patients, who were scheduled for EUS-FNB of a solid pancreatic mass suspected for pancreatic ductal adenocarcinoma (PDAC). In total, seven optical parameters, derived from the absorption acquired spectra, were analyzed: blood volume fraction (BVF), microvascular saturation, average vessel diameter, bilirubin concentration (BIL), Mie amplitude, Mie slope and Rayleigh amplitude. Read More

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Primary T-Cell Lymphoma of the Parotid Gland.

J Coll Physicians Surg Pak 2022 Mar;32(3):392-394

Department of Pathology, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey.

Primary malignant lymphomas of parotid gland are very rare. Most are B-cell lymphomas, and T-cell lymphomas are very rare. Unfortunately, fine needle aspiration biopsy is non-diagnostic. Read More

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Anaplastic thyroid carcinoma with unusual long-term survival: a case report.

J Med Case Rep 2022 Feb 1;16(1):39. Epub 2022 Feb 1.

Departamento de Patología, Hospital General San Juan de Dios, Guatemala, Guatemala.

Background: Anaplastic thyroid carcinoma is a rare, rapidly progressive, and highly aggressive tumor. It has a global annual incidence of 1-2 per million people. It mostly affects older adults and women. Read More

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February 2022

Ameloblastoma with adenoid features: Case report with cyto-histopathologic correlation and molecular findings.

Diagn Cytopathol 2022 Jun 25;50(6):E140-E145. Epub 2022 Jan 25.

Department of Pathology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA.

Ameloblastomas are benign but locally aggressive odontogenic tumors that commonly present as expansile lesions in the tooth-bearing areas. Fine-needle aspiration (FNA) biopsies of ameloblastomas are rare in clinical practice, and only a handful of case reports and series have described their cytologic features. We present the case of a 70-year-old woman with a large and disfiguring maxillary sinus soft tissue mass sampled via transcutaneous FNA. Read More

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Fine-needle aspiration cytology of an intrathyroidal nodule diagnosed as squamous cell carcinoma: A case report.

World J Clin Cases 2021 Nov;9(32):9982-9989

Department of Pathology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China.

Background: Both squamous cell carcinoma (SCC) and papillary thyroid carcinoma (PTC) are common malignant tumors in the neck. However, seldom has SCC of the thyroid been diagnosed. Further, cytological features of SCC and PTC have rarely been reported. Read More

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November 2021

Intrasalivary Thymic Carcinoma: A Case Report and Literature Review.

Head Neck Pathol 2021 Nov 22. Epub 2021 Nov 22.

Department of Pathomorphology, Medical University of Gdansk, Smoluchowskiego 17, Gdańsk, Poland.

Ectopic thymic carcinomas are rarely diagnosed in the thyroid gland, let alone in extrathyroid tissues. In the currently available literature, only five cases of extrathyroidal malignancies with thymic differentiation have been reported as arising in the major salivary glands. A 69-year-old female presented with a slow-growing palpable mass in the left parotid gland. Read More

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November 2021

Isolated poorly differentiated cancer (insular) in a thyroglossal cyst: a case report.

Pan Afr Med J 2021 20;39:254. Epub 2021 Aug 20.

Princess Eman Laboratory Center, King Hussein Medical Center, Amman, Jordan.

A 23-year-old young man presented with a painless neck mass that he noticed slowly growing over the past 4 years. Neck imaging showed an irregular 5 x 5 cm mixed solid and cystic mass in mid neck that looked suspicious but normal looking thyroid and no neck lymphadenopathy. Thyroid uptake scan was within normal also. Read More

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November 2021

Mediastinal Thyroid Carcinoma and Graves' Disease: A Rare Presentation.

Case Rep Endocrinol 2021 12;2021:6584616. Epub 2021 Oct 12.

Serviço de Endocrinologia, Instituto Português de Oncologia de Lisboa Francisco Gentil, Rua Professor Lima Basto, 1099-023 Lisboa, Portugal.

Background: Mediastinal thyroid carcinoma is extremely rare, with few cases reported in the literature. . A 73-year-old man presented with weight loss for 6 months. Read More

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October 2021

Non-neoplastic Lesions among Lateral Neck Mass Specimens in a Tertiary Care Center: A Descriptive Cross-sectional Study.

JNMA J Nepal Med Assoc 2021 Jul 30;59(239):663-666. Epub 2021 Jul 30.

Department of Community Medicine, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.

Introduction: Lateral neck masses present clinically as neoplastic or non-neoplastic lesions of lymph nodes, salivary glands, and thyroid. Non-neoplastic lesions, if evaluated timely, may not transform into malignancy thus reducing clinical burden. A cytomorphological study using fine needle aspiration is a reliable method for the diagnosis of such masses. Read More

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Thyroid hemiagenesis associated with Hurthle cell carcinoma: A case report.

Int J Surg Case Rep 2021 Sep 7;86:106372. Epub 2021 Sep 7.

Surgical Oncology Division, Department of Surgery, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia.

Introduction And Importance: Thyroid hemiagenesis (TH) is a rare congenital anomaly where one lobe fails to develop, especially more frequently occurs on the left lobe. The exact mechanisms for thyroid morphogenesis remain unclear. In this paper, we report a rare case of right lobe TH associated with Hurthle cell carcinoma. Read More

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September 2021

Clavicular Metastasis as an Initial Presentation of Papillary Thyroid Cancer.

Case Rep Endocrinol 2021 26;2021:6662071. Epub 2021 Aug 26.

Division of Endocrinology, University of Florida College of Medicine-Jacksonville, Jacksonville, FL, USA.

Objective: We present the case of a 44-year-old man with a large neck mass to highlight the unique presentation of papillary thyroid carcinoma (PTC) metastatic to the clavicle.

Methods: We reviewed the medical record for a detailed history and physical examination findings. Our radiology colleagues examined the diagnostic imaging studies performed. Read More

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Intraparotid Facial Nerve Schwannoma Mimicking Primary Parotid Neoplasm.

Ear Nose Throat J 2021 Sep 17;100(6_suppl):881S-883S. Epub 2021 Aug 17.

22494Cedars Sinai Sinus Center of Excellence, Los Angeles, CA, USA.

The following report is of a 36-year-old male who presented with a growing mass in the region of the parotid gland. Initial fine needle aspiration biopsy suggested a primary neoplasm of the parotid gland, but subsequent frozen section analysis intraoperatively demonstrated a schwannoma of the facial nerve. An intracapsular enucleation of the schwannoma was performed in order to preserve the fibers of the motor nerve. Read More

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September 2021

Evaluation and Management of a Neck Mass.

Med Clin North Am 2021 Sep 12;105(5):827-837. Epub 2021 Jul 12.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

Neck masses are common physical examination findings seen in the outpatient setting but identifying an underlying cause can be challenging. A careful medical history should be obtained, and a thorough physical examination should be performed, which will guide the need for follow-up examination with imaging, biopsies, and specialist referrals. The goal of this article is to provide a working framework to evaluate and manage some of the most common causes of adult neck masses. Read More

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September 2021

Follicular dendritic cell sarcoma of the cervical lymph node diagnosed on fine needle aspiration cytology.

Cytopathology 2022 01 30;33(1):119-122. Epub 2021 Aug 30.

Department of Pathology, New York University Langone Health, New York, NY, USA.

Follicular dendritic cell sarcomas (FDCS) are rare tumours of lymph nodes and extranodal tissues which are grouped with the histiocytic and dendritic cell neoplasms. The diagnosis is usually made after thorough clinical and pathological examination with immunohistochemical analysis. Difficulties persist in diagnosing FDCS on cytological preparations. Read More

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January 2022