939 results match your criteria Biometrical Journal [Journal]


A Developmental Twin Study of Emotion Recognition and Its Negative Affective Clinical Correlates.

J Am Acad Child Adolesc Psychiatry 2018 Dec 29;57(12):925-933.e3. Epub 2018 Sep 29.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond.

Objective: Youth with psychiatric disorders distinguished by irritability, including depression and associated trait neuroticism, show deficits in the ability to recognize facial expressions of emotion, particularly happiness. However, the contribution of genetic and environmental factors to this ability remains unknown. The present study examined this trait in twins to assess the genetic and environmental influences on face-emotion recognition abilities and their association with irritability, neuroticism, and depression. Read More

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December 2018

Decomposing the causes of the socioeconomic status-health gradient with biometrical modeling.

J Pers Soc Psychol 2018 Nov 8. Epub 2018 Nov 8.

Department of Psychology and Human Development, Vanderbilt University.

The consistent relationship between socioeconomic status (SES) and health has been widely covered in the media and scientific journals, which typically argue that physical-health inequalities are caused by material disadvantage directly or indirectly (e.g., chronic environmental-stress, health care resources, etc. Read More

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November 2018
15 Reads

Sonographic prediction of macrosomia in pregnancies complicated by maternal diabetes: finding the best formula.

Arch Gynecol Obstet 2018 Oct 16. Epub 2018 Oct 16.

Hillel Yaffe Medical Center, Hadera, Israel.

Purpose: To evaluate the best performing formula for macrosomia prediction in pregnancies complicated by diabetes.

Methods: A retrospective analysis was performed of 1060 sonographic fetal biometrical measurements performed within 7 days of delivery in term pregnancies (37-42 gestational weeks) complicated by diabetes. Sonographic prediction of macrosomia (≥ 4000, ≥ 4250, and ≥ 4500 g) was evaluated utilizing ten previously published formulas by: (1) calculating for each macrosomia threshold the sensitivity, specificity, positive and negative predictive value, and ± likelihood ratio for macrosomia prediction; (2) comparing the systematic and random error and the proportion of estimates < 10% of birth weights between macrosomic and non-macrosomic neonates. Read More

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October 2018
3 Reads

GDP-l-fucose synthase is a CD4 T cell-specific autoantigen in DRB3*02:02 patients with multiple sclerosis.

Sci Transl Med 2018 Oct;10(462)

Neuroimmunology and MS Research (nims), Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zürich, Switzerland.

Multiple sclerosis is an immune-mediated autoimmune disease of the central nervous system that develops in genetically susceptible individuals and likely requires environmental triggers. The autoantigens and molecular mimics triggering the autoimmune response in multiple sclerosis remain incompletely understood. By using a brain-infiltrating CD4 T cell clone that is clonally expanded in multiple sclerosis brain lesions and a systematic approach for the identification of its target antigens, positional scanning peptide libraries in combination with biometrical analysis, we have identified guanosine diphosphate (GDP)-l-fucose synthase as an autoantigen that is recognized by cerebrospinal fluid-infiltrating CD4 T cells from HLA-DRB3*-positive patients. Read More

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October 2018
15 Reads

Canakinumab in patients with systemic juvenile idiopathic arthritis and active systemic features: results from the 5-year long-term extension of the phase III pivotal trials.

Ann Rheum Dis 2018 Dec 29;77(12):1710-1719. Epub 2018 Sep 29.

Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Objectives: To evaluate the long-term efficacy and safety of canakinumab in patients with active systemic juvenile idiopathic arthritis (JIA).

Methods: Patients (2-19 years) entered two phase III studies and continued in the long-term extension (LTE) study. Efficacy assessments were performed every 3 months, including adapted JIA American College of Rheumatology (aJIA-ACR) criteria, Juvenile Arthritis Disease Activity Score (JADAS) and ACR clinical remission on medication criteria (CR). Read More

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December 2018
13 Reads

Associations Between Alcohol Involvement and Drive for Thinness and Body Dissatisfaction in Adolescent Twins: A Bivariate Twin Study.

Alcohol Clin Exp Res 2018 Nov 4;42(11):2214-2223. Epub 2018 Sep 4.

Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia.

Background: Alcohol involvement has familial associations with bulimic symptoms (i.e., binge eating, inappropriate compensatory behaviors), with several studies indicating a genetic overlap between the two. Read More

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November 2018
1 Read

Z-scores of early diastolic blood flow widths of mitral and tricuspid valves in normal fetuses and fetuses with dilated coronary sinus.

J Matern Fetal Neonatal Med 2018 Oct 29:1-8. Epub 2018 Oct 29.

a Zhejiang University School of Medicine, Sir Run Run Shaw Hospital , Department of Diagnostic Ultrasound and Echocardiography, Hangzhou , P. R. China.

Objectives: To establish Z-score models for early diastolic blood flow widths of mitral and tricuspid valves in normal fetuses and compare Z-scores and other blood flow dynamic parameters between normal fetuses and fetuses with dilated coronary sinus (CS). This study seeks to assess whether dilated CS affects cardiac structure or hemodynamics.

Methods: One hundred twenty-nine normal fetuses (Group I) and 15 fetuses with dilated CS connected to persistent left superior vena cava (PLSVC) (Group II) were included in this study. Read More

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October 2018

Scrotum bipartite in sheep as a parameter indicative of adaptation to semi-arid climates: A thermographic and reproductive study.

Theriogenology 2018 Nov 29;121:91-96. Epub 2018 Jul 29.

Federal University of Rio Grande do Norte, Natal, RN, Brazil.

With the objective of assessing the influence of scrotum bipartition on scrotum-testiclar thermoregulation and semen quality in sheep native to a semiarid region, 14 adult crossbred rams were placed into groups, GI (7 with bipartition in the scrotum) and GII (7 without bipartition). Images were taken of the caudal scrotum surface using a Fluke (Ti25) thermographic camera, for temperature analysis. Two semen collections were made, at an eight-day interval, by electroejaculation, to analyze macroscopic and microscopic parameters. Read More

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November 2018
4 Reads

Developing sarcopenia criteria and cutoffs for an older Caucasian cohort - a strictly biometrical approach.

Clin Interv Aging 2018 2;13:1365-1373. Epub 2018 Aug 2.

Department of Medical and Life Sciences, University of Furtwangen, Villingen-Schwenningen, Germany.

Background: The aim of this strictly statistical approach was to provide a figure discrimination in a homogeneous cohort that is based on a main component, which includes disability, physical performance, and autonomy parameters.

Methods: We used data of 939 community-dwelling men aged ≥70 years, living in the area of Erlangen-Nürnberg, Germany. Briefly, we conducted a scaled principal component analysis based on criteria related to "physical function", "disability", "weakness", and "autonomy" to identify men who are likely to have sarcopenia as per the recognized sarcopenia criteria. Read More

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November 2018
4 Reads

Potential for Genetic Improvement of the Main Slaughter Yields in Common Carp With Morphological Predictors.

Front Genet 2018 30;9:283. Epub 2018 Jul 30.

Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, University of South Bohemia in České Budějovice, Vodňany, Czechia.

Common carp is a major aquaculture species worldwide, commonly sold alive but also as processed headless carcass or filets. However, recording of processing yields is impossible on live breeding candidates, and alternatives for genetic improvement are either sib selection based on slaughtered fish, or indirect selection on correlated traits recorded . Morphological predictors that can be measured on live fish and that correlate with real slaughter yields hence remain a possible alternative. Read More

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July 2018
4 Reads

The Effect of Feeding Cocoa Powder and on the Composition and Function of Pig Intestinal Microbiome.

Curr Dev Nutr 2018 May 9;2(5):nzy011. Epub 2018 Feb 9.

Office of Dietary Supplements, National Institutes of Health, Bethesda, MD.

Background: Dietary habits have been linked with variability of gut microbiota composition and disease risk.

Objective: The aim of this study was to evaluate the effect of feeding a cocoa powder with or without a probiotic on the composition and function of the fecal microbiome of pigs.

Methods: Four groups of 8 pigs each were fed a standard growth diet supplemented with cocoa powder, (LGG), cocoa powder + LGG, or an equal amount of fiber similar to that found in cocoa powder (control group). Read More

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May 2018
5 Reads

Phenotyping for Genetic Improvement of Feed Efficiency in Fish: Lessons From Pig Breeding.

Front Genet 2018 24;9:184. Epub 2018 May 24.

Biometrical Genetics, Natural Resources Institute Finland (Luke), Jokioinen, Finland.

Feed incurs most of the cost of aquaculture production, so feed efficiency (FE) improvement is of great importance. Our aim is to use work done in pigs to formulate a logical framework for assessing the most useful component traits influencing feed intake (FI) and efficiency in farmed fish - either to identify traits that can together be used for genetic improvement of FE, or as substitute traits for FI recording. Improvement of gross FE in growing fish can be accomplished by selection for increased growth rate. Read More

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May 2018
5 Reads

Etiology of Stability and Growth of Internalizing and Externalizing Behavior Problems Across Childhood and Adolescence.

Behav Genet 2018 07 20;48(4):298-314. Epub 2018 Apr 20.

Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.

Internalizing and externalizing behaviors are heritable, and show genetic stability during childhood and adolescence. Less work has explored how genes influence individual differences in developmental trajectories. We estimated ACE biometrical latent growth curve models for the Teacher Report Form (TRF) and parent Child Behavior Checklist (CBCL) internalizing and externalizing scales from ages 7 to 16 years in 408 twin pairs from the Colorado Longitudinal Twin Study. Read More

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July 2018
3 Reads

Serotonergic gene polymorphisms (5-HTTLPR, 5HTR1A, 5HTR2A), and population differences in aggression: traditional (Hadza and Datoga) and industrial (Russians) populations compared.

J Physiol Anthropol 2018 Apr 16;37(1):10. Epub 2018 Apr 16.

Department of Evolutionary and Developmental Genetics, Koltzov Institute of Developmental Biology, Russian Academy of Sciences, Vavilova St. 26, Moscow, Russia, 119334.

Background: Current knowledge on genetic basis of aggressive behavior is still contradictory. This may be due to the fact that the majority of studies targeting associations between candidate genes and aggression are conducted on industrial societies and mainly dealing with various types of psychopathology and disorders. Because of that, our study was carried on healthy adult individuals of both sex (n = 853). Read More

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April 2018
4 Reads

Ultrasonographic estimation of fetal weight: development of new model and assessment of performance of previous models.

Ultrasound Obstet Gynecol 2018 07 3;52(1):35-43. Epub 2018 Jun 3.

Department of Fetal Medicine, King's College Hospital, London, UK.

Objectives: To develop a new formula for ultrasonographic estimation of fetal weight and evaluate the accuracy of this and all previous formulae in the prediction of birth weight.

Methods: The study population consisted of 5163 singleton pregnancies with fetal biometry at 22-43 weeks' gestation and live birth of a phenotypically normal neonate within 2 days of the ultrasound examination. Multivariable fractional polynomial analysis was used to determine the combination of variables that provided the best-fitting models for estimated fetal weight (EFW). Read More

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July 2018
6 Reads

Editorial for the Biometrical Journal Special Issue ISCB 2016.

Authors:
Nigel Stallard

Biom J 2018 03;60(2):231

Warwick Medical School, University of Warwick, Coventry, UK.

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March 2018
2 Reads

Authors:

Rhinology 2018 Feb 15. Epub 2018 Feb 15.

Background: The lack of nasal tip support resulting in poor protection and projection of the nose is a common cause of nasal obstruction and cosmetic impairment. Although septal cartilage is preferred for restoration of nasal tip support, there is often not enough septal cartilage available. We describe an intercrural columellar strut graft in a circumferential soft tissue pocket: the I-Beam technique. Read More

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February 2018
5 Reads

Long-term results after restoring nasal tip support using auricular cartilage as an intercrural columellar strut graft: the "I-Beam" technique.

Rhinology 2018 Jun;56(2):183-188

Department of Otorhinolaryngology, Head, Neck and Facial Plastic Surgery, Luzerner Kantonsspital, Lucerne, Switzerland.

Background: The lack of nasal tip support resulting in poor protection and projection of the nose is a common cause of nasal obstruction and cosmetic impairment. Although septal cartilage is preferred for restoration of nasal tip support, there is often not enough septal cartilage available. We describe an intercrural columellar strut graft in a circumferential soft tissue pocket: the I-Beam technique. Read More

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June 2018
2 Reads

Detection of evaluation bias caused by genomic preselection.

J Dairy Sci 2018 Apr 4;101(4):3155-3163. Epub 2018 Feb 4.

Natural Resources Institute Finland (Luke), Green Technology, Biometrical Genetics, 31600 Jokioinen, Finland.

The aim of this simulation study was to investigate whether it is possible to detect the effect of genomic preselection on Mendelian sampling (MS) means or variances obtained by the MS validation test. Genomic preselection of bull calves is 1 additional potential source of bias in international evaluations unless adequately accounted for in national evaluations. Selection creates no bias in traditional breeding value evaluation if the data of all animals are included. Read More

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How much confidence do we need in animal experiments? Statistical assumptions in sample size estimation.

J Appl Anim Welf Sci 2018 Oct-Dec;21(4):325-333. Epub 2018 Jan 26.

a Institute of Epidemiology and Medical Biometry , Ulm University , Ulm , Germany.

Statistical sample size calculation is a crucial part of planning nonhuman animal experiments in basic medical research. The 3R principle intends to reduce the number of animals to a sufficient minimum. When planning experiments, one may consider the impact of less rigorous assumptions during sample size determination as it might result in a considerable reduction in the number of required animals. Read More

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January 2018

Validation of consistency of Mendelian sampling variance.

J Dairy Sci 2018 Mar 28;101(3):2187-2198. Epub 2017 Dec 28.

Natural Resources Institute Finland, Green Technology, Biometrical Genetics, 31600 Jokioinen, Finland.

Experiences from international sire evaluation indicate that the multiple-trait across-country evaluation method is sensitive to changes in genetic variance over time. Top bulls from birth year classes with inflated genetic variance will benefit, hampering reliable ranking of bulls. However, none of the methods available today enable countries to validate their national evaluation models for heterogeneity of genetic variance. Read More

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Morphological, biometrical and molecular characterization of Archaeopsylla erinacei (Bouché, 1835).

Bull Entomol Res 2018 Dec 22;108(6):726-738. Epub 2017 Dec 22.

Department of Microbiology and Parasitology,Faculty of Pharmacy,University of Seville,Profesor García González 2,41012 Seville,Spain.

In the present work, we carried out a morphological, biometrical and molecular study of the species Archaeopsylla erinacei (Bouché, 1835) and their subspecies: Archaeopsylla erinacei erinacei (Bouché, 1835) and Archaeopsylla erinacei maura (Jordan & Rothschild, 1912) isolated from hedgehogs (Erinaceus europaeus) from different geographical regions (Seville and Corse). We have found morphological differences in females of A. erinacei from the same geographical origin that did not correspond with molecular differences. Read More

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December 2018
1 Read

Morphological-molecular characterization and phylogenetic relationships of a new Trichuris species (Nematoda: Trichuridae) parasitic on Holochilus chacarius (Cricetidae: Sigmodontinae) from the Chaco ecoregion (Argentina).

Infect Genet Evol 2018 03 12;58:66-76. Epub 2017 Dec 12.

Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Seville, Spain.

A new Trichuris species isolated from Holochilus chacarius (Cricetidae: Sigmodontinae) from the Chaco ecoregion in Argentina is described based on morphological characteristics and mitochondrial (cox1, cob) and nuclear (ITS2) markers. The new species is distinguished from 27 species of Trichuris from North and South American rodents based on morphological and biometrical features, such as the absence of a spicular tube, presence of a cylindrical spicular sheath, non-protrusive vulva, length of spicule, and proximal and distal cloacal tube. In addition, the results based on three molecular markers of the new species and three Trichuris species previously analysed from sigmodontine rodents: Trichuris pardinasi, Trichuris navonae and Trichuris bainae confirmed that the specimens here studied belong to a different species. Read More

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March 2018
7 Reads

Meta-analysis for the comparison of two diagnostic tests-A new approach based on copulas.

Stat Med 2018 Feb 29;37(5):739-748. Epub 2017 Nov 29.

German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Institute for Biometrics and Epidemiology, 40225 Düsseldorf, Germany.

Meta-analysis of diagnostic studies is still field of ongoing biometrical research. Especially, clinical researchers call for methods that allow for a comparison of different diagnostic tests to a common gold standard. Focussing on two diagnostic tests, the main parameters of interest are differences of sensitivities and specificities (with their corresponding confidence intervals) between the two diagnostic tests while accounting for the various associations across the two tests and the single studies. Read More

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February 2018
1 Read

Differentiating Merkel cell carcinoma of lymph nodes without a detectable primary skin tumor from other metastatic neuroendocrine carcinomas: The ELECTHIP criteria.

J Am Acad Dermatol 2018 05 24;78(5):964-972.e3. Epub 2017 Nov 24.

Department of Pathology, Université Francois Rabelais, Centre Hospitalier Universitaire de Tours, Tours, France; Biologie des Infections à Polyomavirus Team Unite Mixte de Recherche 1282 Infectiologie et Santé Publique, Institut National de la Recherche Agronomique (INRA), Université Francois Rabelais, Tours, France.

Background: Merkel cell carcinoma (MCC) can present as a cutaneous tumor or a lymph node metastasis without a primary tumor. MCC presenting without a primary tumor (MCCWOPT) can be misinterpreted on histologic examination as lymph node metastasis (LNM) from another neuroendocrine carcinoma (LNMNEC). However, this distinction is crucial for therapeutic management. Read More

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May 2018
13 Reads

Reduced frontal grey matter, life history of aggression, and underlying genetic influence.

Psychiatry Res Neuroimaging 2018 01 13;271:126-134. Epub 2017 Nov 13.

Clinical Neuroscience Research Unit, Department of Psychiatry and Behavioral Neuroscience, Pritzker School of Medicine, The University of Chicago, Chicago 60637, IL, USA.

Physically healthy, adult, same-sexed twins (n = 287) from a population-based twin cohort underwent high-resolution magnetic resonance imaging (MRI) to identify fronto-limbic brain regions significantly associated with lifetime history of aggression. MRI scans used a 3D magnetization-prepared rapid acquisition gradient-echo (MP-RAGE) sequence, for voxel-based morphometry (VBM) and history of aggressive behavior was assessed using the Life History of Aggression measure. Aggression had modest, inverse associations with grey matter volume (GMV) in medial prefrontal cortex (mPFC, b = -0. Read More

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January 2018

The Influence of Class II Division 2 Malocclusions on the Harmony of the Human Face Profile.

Authors:
Tatjana Perović

Med Sci Monit 2017 Nov 24;23:5589-5598. Epub 2017 Nov 24.

Medical Faculty, University of Niš, Niš, Serbia.

BACKGROUND Persons with class II division 2 malocclusion are characterized by a very specific dento-skeletal and soft-tissue profile (a profile in which a protruding nose and chin, retruding lips, concave and shortened lower third of the face, and gummy smile are dominant), which is the opposite of the currently modern profiles (convex profile of protruding lips and small chin). The aim of this research was to determine the differences in parameters of harmonies of facial profiles between persons with class II division 2 malocclusions and class I, and to establish the significance of those differences. MATERIAL AND METHODS For this study, 50 patients with class II division 2 malocclusions and 50 patients with class I were selected; profile photos were recorded and a photometric analysis was done: a type of profile according to Schwarz, the shape of a nose, the prominence of chin, biometrical field, the position of lips in relation to the tangent Sn-Pg, S-line (Steiner), E-line (Riketts) and a facial angle according to Arnett. Read More

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November 2017
2 Reads

Prepubertal chrysin exposure upregulates either AR in male ventral prostate or AR and ERα in Skene's paraurethral gland of pubertal and adult gerbils.

Fitoterapia 2018 Jan 10;124:137-144. Epub 2017 Nov 10.

Department of Histology, Embryology and Cell Biology, Laboratory of Histophysiology, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Goiás 74001970, Brazil. Electronic address:

Chrysin is a plant-derived polyphenol that has the potential to increase endogenous testosterone levels both by inhibiting the aromatase enzyme and by stimulating testicular steroidogenesis. The effects of chrysin on the prostate are unknown, especially during its development and functional maturation. Thus, the aim of this study was to evaluate the effects of chrysin prepubertal exposure on the male and female prostates of both pubertal and adult gerbils. Read More

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January 2018
11 Reads

Flavanol-Rich Cocoa Powder Interacts with Lactobacillus rhamnossus LGG to Alter the Antibody Response to Infection with the Parasitic Nematode Ascaris suum.

Nutrients 2017 Oct 12;9(10). Epub 2017 Oct 12.

USDA, ARS, Beltsville Human Nutrition Research Center, Diet, Genomics, and Immunology Laboratory, Beltsville, MD 20705, USA.

Consumption of the probiotic bacteria and flavanol-rich cocoa have purported immune modulating effects. This study compared the host response to infection with in three-month-old pigs fed a standard growth diet supplemented with a vehicle control: LGG, cocoa powder (CP) or LGG + CP. Pigs were inoculated with infective . Read More

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October 2017
39 Reads

The Mechanical Properties and Biometrical Effect of 3D Preformed Titanium Membrane for Guided Bone Regeneration on Alveolar Bone Defect.

Biomed Res Int 2017 5;2017:7102123. Epub 2017 Sep 5.

Department of Prosthodontics, Dental Research Institute, Institute of Translational Dental Sciences, BK21 PLUS Project, School of Dentistry, Pusan National University, Yangsan 50612, Republic of Korea.

The purpose of this study is to evaluate the effect of three-dimensional preformed titanium membrane (3D-PFTM) to enhance mechanical properties and ability of bone regeneration on the peri-implant bone defect. 3D-PFTMs by new mechanically compressive molding technology and manually shaped- (MS-) PFTMs by hand manipulation were applied in artificial peri-implant bone defect model for static compressive load test and cyclic fatigue load test. In 12 implants installed in the mandibular of three beagle dogs, six 3D-PFTMs, and six collagen membranes (CM) randomly were applied to 2. Read More

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May 2018
3 Reads

Siblings and Adolescent Weapon Carrying: Contributions of Genetics, Shared Environment, and Nonshared Environment.

Authors:
Lacey N Wallace

Youth Violence Juv Justice 2017 Jul 18;15(3):264-280. Epub 2016 Mar 18.

Department of Criminal Justice, Penn State Altoona, Altoona, PA, USA.

Many past studies have observed evidence of sibling similarity and influence for delinquency and substance use. However, studies of sibling similarity for adolescent weapon carrying, particularly for weapons beyond firearms, are largely absent from the literature. The present study assesses sibling similarity in weapon carrying as well as the relative contributions of genetics, shared environment, and nonshared environment. Read More

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Clinical and biometrical 12-month follow-up in patients after reconstruction of the sural nerve biopsy defect by the collagen-based nerve guide Neuromaix.

Eur J Med Res 2017 Sep 22;22(1):34. Epub 2017 Sep 22.

Department of Plastic Surgery, Reconstructive and Hand Surgery, Burn Center, RWTH Aachen University Hospital, Aachen, Germany.

Many new strategies for the reconstruction of peripheral nerve injuries have been explored for their effectiveness in supporting nerve regeneration. However only a few of these materials were actually clinically evaluated and approved for human use. This open, mono-center, non-randomized clinical study summarizes the 12-month follow-up of patients receiving reconstruction of the sural nerve biopsy defect by the collagen-based nerve guide Neuromaix. Read More

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September 2017
6 Reads

Different formulas, different thresholds and different performance-the prediction of macrosomia by ultrasound.

J Perinatol 2017 Dec 14;37(12):1285-1291. Epub 2017 Sep 14.

Hillel Yaffe Medical Center, Hadera, Israel.

Objective: The sonographic prediction of fetal macrosomia affects obstetrical decision regarding the timing and mode of delivery. We aimed to compare the accuracy of various formulas for prediction of macrosomia at different thresholds.

Study Design: This was a retrospective cohort study of singleton gestations at term, with fetal biometrical measurements taken up to 7 days prior to delivery (2007 to 2014). Read More

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December 2017
2 Reads

Comparison of coronary sinus diameter Z-scores in normal fetuses and fetuses with persistent left superior vena cava (PLSVC).

Int J Cardiovasc Imaging 2018 Feb 14;34(2):223-228. Epub 2017 Aug 14.

Department of Diagnostic Ultrasound and Echocardiography, Sir Run Shaw Hospital, Zhejiang University College of Medicine, No.3 East Qingchun Road, Hangzhou, 310016, China.

To establish Z-score reference ranges for coronary sinus (CS) diameter in normal fetuses and explore the diagnostic value of CS Z-score in fetuses with persistent left superior vena cava (PLSVC). Study of 235 normal fetuses and 30 fetuses with PLSVC was involved. Noncardiac biometrical parameters included biparietal diameter (BPD), femoral length (FL), heart area (HA), gestation age (GA). Read More

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February 2018
46 Reads

Effect of Milk Fermented with Lactic Acid Bacteria on Diarrheal Incidence, Growth Performance and Microbiological and Blood Profiles of Newborn Dairy Calves.

Probiotics Antimicrob Proteins 2018 Dec;10(4):668-676

Centro de Referencia para Lactobacilos (CERELA-CONICET), Chacabuco 145, 4000, San Miguel de Tucumán, Argentina.

The effect of the administration of milk fermented with lactic acid bacteria to calves was evaluated. The strains included were: Lactobacillus murinus CRL1695, Lact. mucosae CRL1696, Lact. Read More

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December 2018
1 Read

Estimation of genetic parameters of the productive and reproductive traits in Ethiopian Holstein using multi-trait models.

Asian-Australas J Anim Sci 2017 Nov 27;30(11):1550-1556. Epub 2017 Jun 27.

Natural Resources Institute Finland (Luke), Biometrical Genetics, Jokioinen 31600, Finland.

Objective: This study estimated the genetic parameters for productive and reproductive traits.

Methods: The data included production and reproduction records of animals that have calved between 1979 and 2013. The genetic parameters were estimated using multivariate mixed models (DMU) package, fitting univariate and multivariate mixed models with average information restricted maximum likelihood algorithm. Read More

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November 2017
4 Reads

Anti-obesogenic effects of WY14643 (PPAR-alpha agonist): Hepatic mitochondrial enhancement and suppressed lipogenic pathway in diet-induced obese mice.

Biochimie 2017 Sep 12;140:106-116. Epub 2017 Jul 12.

Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Brazil. Electronic address:

Non-alcoholic fatty liver disease (NAFLD) presents with growing prevalence worldwide, though its pharmacological treatment remains to be established. This study aimed to evaluate the effects of a PPAR-alpha agonist on liver tissue structure, ultrastructure, and metabolism, focusing on gene and protein expression of de novo lipogenesis and gluconeogenesis pathways, in diet-induced obese mice. Male C57BL/6 mice (three months old) received a control diet (C, 10% of lipids, n = 10) or a high-fat diet (HFD, 50% of lipids, n = 10) for ten weeks. Read More

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September 2017
14 Reads

Biometrical evaluation of the performance of the revised OECD Test Guideline 402 for assessing acute dermal toxicity.

Regul Toxicol Pharmacol 2017 Oct 11;89:26-39. Epub 2017 Jul 11.

Dow AgroSciences Ltd, European Development Centre, 3B Park Square, Milton Park, Abingdon, Oxon, OX14 4RN, UK.

A comprehensive biometrical assessment was conducted to compare the performance of multiple test designs for acute dermal systemic toxicity to support the animal welfare update to the original OECD Test Guideline (TG) 402 for acute dermal toxicity. The test designs evaluated included: (1) two, three, or five animals per dose group (2) evident toxicity or lethality endpoints and (3) absence or presence of a one-animal sighting study. The revision of TG 402 respected the 3R principles (replace, reduce, refine) of animal testing. Read More

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October 2017
4 Reads

Shared familial risk between bulimic symptoms and alcohol involvement during adolescence.

J Abnorm Psychol 2017 Jul;126(5):506-518

Department of Psychiatry, VA Commonwealth University.

Twin studies show the established relation between bulimic symptoms and problematic alcohol involvement in adult females is partly due to shared familial factors, specifically shared genetic effects. However, it is unclear if similar shared etiological factors exist during adolescence or in males. We examined the familial overlap (i. Read More

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July 2017
19 Reads

Influence of CYP2C19 Genotypes on the Occurrence of Adverse Drug Reactions of Voriconazole among Hematological Patients after Allo-HSCT.

Pathol Oncol Res 2018 Jul 6;24(3):541-545. Epub 2017 Jul 6.

Department of Clinical Pharmacology, Faculty of Pharmacy, Wrocław Medical University, 211a Borowska St, 50-556, Wrocław, Poland.

The aim of this study was to determine the influence of different CYP2C19 genotypes on selected liver function parameters, and ADR occurrence during VCZ prophylaxis in adult patients after allo-HSCT (allogeneic hematopoietic stem cell transplantation). CYP2C19 mutations were determined in a cohort of 30 adults using PCR-RFLP methods established by Sim et al. and Goldstein and Blaisdell. Read More

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July 2018
36 Reads

Geometric morphometrics in mosquitoes: What has been measured?

Infect Genet Evol 2017 10 30;54:205-215. Epub 2017 Jun 30.

Instituto Butantan, Av. Vital Brazil 1500, Butantã, São Paulo, SP CEP 0553-900, Brazil; Instituto de Medicina Tropical, Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar 470, Jardim América, São Paulo, SP CEP 05403-000, Brazil.

The field of morphometrics is developing quickly. Recent advances have enabled geometric techniques to be applied to many zoological problems, particularly those involving epidemiologically-relevant mosquitoes. Herein, we briefly introduce geometric morphometric (GM) techniques and then review selected groups of mosquitoes (Culicidae) to which those techniques have been applied. Read More

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October 2017
14 Reads

Stratified exact tests for the weak causal null hypothesis in randomized trials with a binary outcome.

Authors:
Yasutaka Chiba

Biom J 2017 Sep 12;59(5):986-997. Epub 2017 Jun 12.

Clinical Research Center, Kinki University Hospital, 377-2 Ohno-higashi, Osakasayama, Osaka, Japan.

Fisher's exact test is commonly used to compare two groups when the outcome is binary in randomized trials. In the context of causal inference, this test explores the sharp causal null hypothesis (i.e. Read More

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September 2017
6 Reads

A morphometric system to distinguish sheep and goat postcranial bones.

PLoS One 2017 8;12(6):e0178543. Epub 2017 Jun 8.

Department of Archaeology, University of Sheffield, Northgate House, Sheffield, United Kingdom.

Distinguishing between the bones of sheep and goat is a notorious challenge in zooarchaeology. Several methodological contributions have been published at different times and by various people to facilitate this task, largely relying on a macro-morphological approach. This is now routinely adopted by zooarchaeologists but, although it certainly has its value, has also been shown to have limitations. Read More

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September 2017

Excimer Laser Surgery: Biometrical Iris Eye Recognition with Cyclorotational Control Eye Tracker System.

Sensors (Basel) 2017 May 25;17(6). Epub 2017 May 25.

Swiss Eye Research Foundation, Eye Clinic ORASIS, 5734 Reinach AG, Switzerland.

A prospective comparative study assessing the importance of the intra-operative dynamic rotational tracking-especially in the treatment of astigmatisms in corneal refractive Excimer laser correction-concerning clinical outcomes is presented. The cyclotorsion from upright to supine position was measured using iris image comparison. The Group 1 of patients was additionally treated with cyclorotational control and Group 2 only with X-Y control. Read More

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May 2017
3 Reads

Redescription and genetic characterization of Cystidicoloides vaucheri, including first description of male and current status on the phylogeny of Cystidicolidae (Nematoda: Habronematoidea).

J Helminthol 2018 May 31;92(3):387-394. Epub 2017 May 31.

Departamento de Parasitologia Animal, and Programa de Pós-Graduação em Ciências Veterinárias,Universidade Federal Rural do Rio de Janeiro (UFRRJ),Caixa Postal 74540,Seropédica, RJ,23851-970,Brazil.

Cystidicoloides vaucheri collected in the stomach of the redtail catfish Phractocephalus hemioliopterus from River Acre, State of Acre, Brazil is redescribed, including the first description of males and the first genetic characterization based upon 18S and 28S genes of the rRNA. Newly collected females were biometrically smaller than those reported in the original description, but similar morphology shared by the two samples revealed that they belong to the same species. Scanning electron micrographs showed the accurate structure of the cephalic region, described here in detail. Read More

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May 2018
16 Reads

Minimum Volume Discussion in the Treatment of Colon and Rectal Cancer: A Review of the Current Status and Relevance of Surgeon and Hospital Volume regarding Result Quality and the Impact on Health Economics.

Visc Med 2017 May 20;33(2):140-147. Epub 2017 Apr 20.

Forschungsgruppe Onkologie Gastrointestinale Tumoren (FOGT), University of Ulm, Ulm, Germany.

Background: To answer the question whether minimum caseloads need to be stipulated in the German S3 (or any other) guidelines for colorectal cancer, we analyzed the current representative literature. The question is important regarding medical quality as well as health economics and policy.

Methods: A literature research was conducted in PubMed for papers concerning 'colon cancer' (CC), 'rectal cancer' (RC), and 'colorectal cancer' (CRC), with 'results', 'quality', and 'mortality' between the years 2000 and 2016 being relevant factors. Read More

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May 2017
10 Reads

Solving efficiently large single-step genomic best linear unbiased prediction models.

J Anim Breed Genet 2017 Jun;134(3):264-274

Natural Resources Institute Finland (Luke), Green Technology, Biometrical Genetics, Jokioinen, Finland.

Single-step genomic BLUP (ssGBLUP) requires a dense matrix of the size equal to the number of genotyped animals in the coefficient matrix of mixed model equations (MME). When the number of genotyped animals is high, solving time of MME will be dominated by this matrix. The matrix is the difference of two inverse relationship matrices: genomic (G) and pedigree (A ). Read More

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June 2017
3 Reads

The Sleeping Remnant. Effect of Roux-En-Y Gastric Bypass on Plasma Levels of Gastric Biomarkers in Morbidly Obese Women: A Prospective Longitudinal Study.

Obes Surg 2017 07;27(7):1901-1905

Department of Clinical and Experimental Medicine, University of Parma, School of Medicine, Via Gramsci 14, 43126, Parma, Italy.

Background: Morpho-functional modifications of the gastric remnant after Roux-en-Y gastric bypass (RYGB) have not been completely defined, due to its inaccessibility for bioptic mapping. The aim of the study is to evaluate such modifications using Gastropanel®, a non-invasive blood test cross-checking four gastric biomarkers, able to provide a snapshot of mucosa conditions.

Subjects And Methods: Twenty-four women undergoing RYGB were prospectively enrolled. Read More

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July 2017
9 Reads

Ovarian follicle development and genital tract characteristics in different birthweight gilts at 150 days of age.

Reprod Domest Anim 2017 Oct 22;52(5):756-762. Epub 2017 Apr 22.

Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.

In the last decades, selection for improved prolificacy has resulted in higher litter sizes and has thereby increased the proportion of low birthweight (LW) piglets. It is well documented that LW piglets have lower growth performance, muscle accretion and poor carcass quality. However, little is known about the relations of birthweight with subsequent reproductive performance in gilts. Read More

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October 2017

Use of multi-trait and random regression models to identify genetic variation in tolerance to porcine reproductive and respiratory syndrome virus.

Genet Sel Evol 2017 04 19;49(1):37. Epub 2017 Apr 19.

The Roslin Institute & R(D)SVS, University of Edinburgh, Edinburgh, Midlothian, UK.

Background: A host can adopt two response strategies to infection: resistance (reduce pathogen load) and tolerance (minimize impact of infection on performance). Both strategies may be under genetic control and could thus be targeted for genetic improvement. Although there is evidence that supports a genetic basis for resistance to porcine reproductive and respiratory syndrome (PRRS), it is not known whether pigs also differ genetically in tolerance. Read More

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April 2017
5 Reads