1,531 results match your criteria Biomedica[Journal]


Aptamers as a novel diagnostic and therapeutic tool and their potential use in parasitology

Biomedica 2020 05 1;40(Supl. 1):148-165. Epub 2020 May 1.

Instituto Colombiano de Medicina Tropical, Universidad CES, Medellín, Colombia.

Aptamers are single-stranded DNA or RNA sequences that adopt unique three-dimensional structures that allow them to recognize a specific target with high affinity. They can potentially be used for the diagnosis of diseases, as new therapeutic agents, for the detection of food risks, as biosensors, for the detection of toxins, and as drug carriers and nanoparticle markers, among other applications. To date, an aptamer called pegaptanib is the only aptamer approved by the Food and Drug Administration (FDA) for commercial use. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4765DOI Listing

Comparison of Escherichia coli antibiotic-resistance profiles and incidence of betalactamase phenotypes in three private health facilities in Perú

Biomedica 2020 05 1;40(Supl. 1):139-147. Epub 2020 May 1.

Laboratorio de Microbiología, Hospital Nacional Docente "Madre Niño San Bartolomé", Lima, Perú.

Introduction: The appearance of multidrug-resistant and beta-lactamase producing enterobacteria in outpatient care facilities represent a public health problem in Perú. Objective: To compare the resistance profiles of uropathogenic Escherichia coli and to identify extended-spectrum beta-lactamase-producing phenotypes in three private health facilities located in the Peruvian coast, Andean and jungle regions. Materials and methods: We conducted a descriptive study on 98 urine samples from Lima (coast), Juliaca (Andean region) and Iquitos (jungle region) during 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4772DOI Listing

Satisfaction and knowledge among patients with HIV after switching from tenofovir to tenofovir alafenamide in regimens containing emtricitabine and rilpivirine

Biomedica 2020 05 1;40(Supl. 1):132-138. Epub 2020 May 1.

Servicio de Farmacia, Hospital Universitario Ramón y Cajal, Madrid, España.

Introduction: Satisfaction and knowledge among patients with HIV after switching from tenofovir to tenofovir/alafenamide remain unexplored. Given that both parameters are associated with better health outcomes it is relevant to measure them in patients during routine clinical practice. Objective: To evaluate the degree of knowledge and satisfaction in patients who had their antiretroviral regimen switched from rilpivirine (RPV)/emtricitabine (FTC)/TDF to RPV/FTC/TAF. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4989DOI Listing

Comparison of quick SOFA and SIRS scales at the bedside of patients with Staphylococcus aureus bacteremia

Biomedica 2020 05 1;40(Supl. 1):125-131. Epub 2020 May 1.

Grupo de Investigación en Medicina interna, Universidad Tecnológica de Pereira, Pereira, Colombia.

Introduction: One of the primary causes of community-acquired bacteremia also associated with nosocomial infections is Staphylococcus aureus, which is responsible for a high percentage of complications leading to high morbidity and mortality rates. The systemic inflammatory response syndrome (SIRS) criteria have been traditionally used to evaluate the presence of sepsis; however, recent evidence questions its predictive value due to its low sensitivity and specificity. In 2016, new criteria for sepsis were published and a new tool emerged, quick SOFA (qSOFA), for the rapid evaluation of infection in emergency services. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4943DOI Listing

Salivary markers of oxidative stress and periodontal pathogens in patients with periodontitis from Santander, Colombia.

Biomedica 2020 05 1;40(Supl. 1):113-124. Epub 2020 May 1.

Facultad de Odontología, Universidad Antonio Nariño, Bucaramanga, Colombia.

Introduction: Periodontitis affects more than 20% of the Latin American population. Oxidative markers are associated with greater progression of periodontitis; therefore, its role in pathogenesis should be studied.

Objective: To determine the prevalence of the main oral bacteria and viruses associated with periodontitis and estimate the total antioxidant capacity and lipid peroxidation in saliva from patients with periodontitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.5149DOI Listing

Risk factors associated with pulmonary tuberculosis relapses in Cali, Colombia.

Biomedica 2020 05 1;40(Supl. 1):102-112. Epub 2020 May 1.

Fundación para la Producción y Gestión del Conocimiento, Cali, Colombia .

Introduction: Relapses in tuberculosis occur due to endogenous reactivations or exogenous reinfections and represent up to 27% of tuberculosis cases. Its importance lies in the risk of the appearance of multidrug-resistant Mycobacterium tuberculosis strains. According to the reports published in 2011 by the Colombian Instituto Nacional de Salud, there were 572 relapse cases reported in the country, i. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.5061DOI Listing

In vitro effectivity of three approved drugs and their synergistic interaction against Leishmania infantum.

Biomedica 2020 05 1;40(Supl. 1):89-101. Epub 2020 May 1.

Medical Parasitology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

Introduction: Leishmaniasis remains one of the neglected tropical diseases. Repurposing existing drugs has proven to be successful for treating neglected tropical diseases while combination therapy is a strategic alternative for the treatment of infectious diseases. Auranofin, lopinavir/ritonavir, and sorafenib are FDA approved drugs used in the treatment of diverse diseases by acting on different essential biological enzymes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4891DOI Listing

Molecular characterization of Epstein-Barr virus variants detected in the oral cavity of adolescents in Cali, Colombia

Biomedica 2020 05 1;40(Supl. 1):76-88. Epub 2020 May 1.

Departamento de Biología, Facultad de Ciencias Naturales y Exactas, Universidad del Valle, Cali, Colombia.

Introduction: The Epstein-Barr virus (EBV) is an ubiquitous and oncogenic virus associated with the development of diseases such as infectious mononucleosis, Burkitt’s lymphoma, nasopharyngeal carcinoma, and other neoplasms. Currently, two types are recognized: EBV-1 and EBV-2, which have genetic differences with their EBNA nuclear antigens. Likewise, due to the high degree of heterogeneity and variability found in the LMP1 protein of the virus, variants associated with pathogenesis or specific geographic regions have been described. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4917DOI Listing

Prevalence of leptospirosis in vaccinated working dogs and humans with occupational risk

Biomedica 2020 05 1;40(Supl. 1):62-75. Epub 2020 May 1.

Grupo CIENVET, Departamento Salud Animal, Facultad de Ciencias Agropecuarias, Universidad de Caldas, Manizales, Colombia.

Introduction: Working dogs have been identified as a risk group for developing leptospirosis because they can be infected by Leptospira spp., which can be kept in the renal tubules and interstices for a long time, making them carriers and sources of infection for other hosts, including humans. Objective: To establish the prevalence of Leptospira spp. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.5009DOI Listing

Leishmaniasis en Bolivia. Comprehensive review and current status in Tarija, in the border with Argentina

Biomedica 2020 05 1;40(Supl. 1):45-61. Epub 2020 May 1.

Instituto Nacional Medicina Tropical, Puerto Iguazú, Misiones, Argentina.

Introduction: In the department of Tarija in the Bolivian-Argentine border, human cases with ulcers on uncovered parts of the skin plus clinical and epidemiological characteristics related to leishmaniasis were reported for the first time in 1997. Objective: To describe and to verify the presence of leishmaniasis in Tarija, sixth endemic department in Bolivia. Materials and methods: We conducted both an outbreak study (November, 1998, to December, 2002) and a longitudinal study (1997 to 2018) in humans, as well as captures of Phlebotominae and potential reservoirs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4990DOI Listing

Methicillin-resistant Staphylococcus aureus nasal colonization in cardiovascular surgery patients at a university hospital in Bogotá, Colombia

Biomedica 2020 05 1;40(Supl. 1):37-44. Epub 2020 May 1.

Grupo de Enfermedades Infecciosas, Departamento de Microbiología, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.

Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a microorganism that colonizes nostrils and different parts of the body, which is considered a risk factor to acquire invasive infections, especially in cardiovascular surgery patients. Objective: To determine the frequency of nasal colonization by MRSA and to establish the clinical characteristics in patients scheduled for cardiovascular surgery. Materials and methods: This was a descriptive study conducted between February and December, 2015. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4791DOI Listing

Fatal Strongyloides stercoralis hyperinfection syndrome in an alcoholic diabetic patient from México

Biomedica 2020 05 1;40(Supl. 1):32-36. Epub 2020 May 1.

Escuela de Medicina, Universidad del Valle, Cali, Colombia.

Strongyloides stercoralis hyperinfection syndrome is a medical emergency that requires a high level of suspicion. Immunocompromised patients are at high risk of hyperinfection syndrome; however, malnutrition, alcoholism, and diabetes mellitus also need to be considered as predisposing factors. The diagnosis and treatment of Strongyloides hyperinfection are challenging and patients often have severe complications. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.5071DOI Listing
May 2020
0.617 Impact Factor

Leprosy in the Colombian island of Providencia

Biomedica 2020 05 1;40(Supl. 1):26-31. Epub 2020 May 1.

Oficina de Docencia e Investigación, Hospital Universitario Centro Dermatológico Federico Lleras Acosta, Bogotá, D.C., Colombia; Facultad de Medicina, Universidad de la Sabana, Chía, Colombia.

San Andrés and Providencia are Colombian islands in the Caribbean Sea. San Andrés has 68,283 inhabitants and has registered cases of leprosy in immigrants from continental Colombia. Providencia has 5,037 inhabitants and historically health programs did not have records of the disease, but in 2009 two cases of multibacillary histoid leprosy were confirmed and, subsequently, another two, which represents a prevalence of 8 cases per 10,000 inhabitants and places the island as a hyperendemic site for leprosy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4974DOI Listing

Tuberculous pericarditis

Biomedica 2020 05 1;40(Supl. 1):23-25. Epub 2020 May 1.

Departamento de Patología y Laboratorios, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, D.C., Colombia; Departamento de Patología, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, D.C., Colombia; Departamento de Microbiología, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, D.C., Colombia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4911DOI Listing

Adrenal paracoccidioidomycosis

Biomedica 2020 05 1;40(Supl. 1):20-22. Epub 2020 May 1.

Departamento de Patología, Universidad de Antioquia, Medellín, Colombia.

Primary adrenal insufficiency is a defect in glucocorticoid, mineralocorticoid and sexual androgens production. Patients with this disorder have low cortisol levels and aldosterone deficiency with concomitant hyponatremia and hyperkalemia. The most common etiology of this disease is the production of antibodies against the enzyme 21 hydroxylase. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4844DOI Listing

With regard to the bicentennial of the independence of Colombia: Reading practices of Antonio Nariño and the development of a presumably effective vaccine against smallpox

Biomedica 2020 05 1;40(Supl. 1):8-19. Epub 2020 May 1.

Facultad de Ciencias de la Salud, Pontificia Universidad Javeriana, Cali, Colombia; Facultad de Humanidades, Universidad del Valle, Cali, Colombia.

Introduction: The social history of written culture reflects the reading and writing habits and practices that allow us to appropriate the texts to build our sense of community. Hence, the library of individuals reflects their reading habits, their way of imagining nature, their relationship with political and religious power, and their involvement with society. Objective: To interpret Antonio Nariño’s reading practices by means of the medical books in his library to approach the way he developed a presumably effective vaccine against smallpox. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.5024DOI Listing

[Infecciones en el trópico: retos para la investigación aplicada].

Biomedica 2020 May 1;40(Supl. 1):5-7. Epub 2020 May 1.

Junta Directiva, Asociación Colombiana de Parasitología y Medicina Tropical.

View Article

Download full-text PDF

Source

[Factores socioeconómicos y clínicos asociados con infecciones oportunistas en pacientes con HIV afiliados al sistema de salud].

Biomedica 2020 Mar 1;40(1):208-210. Epub 2020 Mar 1.

Semillero de Investigación SISALUD, Facultad Nacional de Salud Pública, Universidad de Antioquia, Medellín, Colombia.

View Article

Download full-text PDF

Source
March 2020
0.617 Impact Factor

Candidemia in Colombia

Biomedica 2020 03 1;40(1):195-207. Epub 2020 Mar 1.

Departamento Médico, Pfizer, Bogotá, D.C., Colombia.

In Colombia, especially in intensive care units, candidemia is a frequent cause of infection, accounting for 88% of fungal infections in hospitalized patients, with mortality ranging from 36% to 78%. Its incidence in Colombia is higher than that reported in developed countries and even higher than in other Latin American countries. First, the patient’s risk factors should be considered, and then clinical characteristics should be assessed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4400DOI Listing

Breast cancer in six families from Tolima and Huila: BRCA1 3450del4 mutation

Biomedica 2020 03 1;40(1):185-194. Epub 2020 Mar 1.

Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Universidad del Tolima, Ibagué, Colombia.

Introduction: Breast cancer is a worldwide public health problem; between 5% and 10% of the cases present familial aggregation explained by genes of high risk such as BRCA1 and BRCA2. The founding origin of the deletion BRCA1 3450del4 in Colombia has been previously reported. Objective: To carry out in six families from Tolima and Huila departments a descriptive analysis of the presence of the BRCA1 3450del4 mutation associated with breast cancer and familial aggregation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4673DOI Listing

Clinical and metabolic effect of a multidisciplinary intervention through a comprehensive care program for children and adolescents with obesity

Biomedica 2020 03 1;40(1):166-184. Epub 2020 Mar 1.

Programa de Obesidad Infantil, Hospital Universitario de San Vicente Fundación, Medellín, Colombia; Dirección de Investigaciones, Hospital Universitario de San Vicente Fundación, Medellín, Colombia.

Introduction: The approach to childhood obesity requires multidisciplinary programs including all the dimensions susceptible to management. Objective: To describe the clinical and metabolic changes in patients with obesity after a comprehensive care program for childhood obesity. Materials and methods: We conducted a retrospective observational and analytical study in a cohort of patients between 6 and 17 years old treated in the obesity program at the Hospital Universitario San Vicente Fundación (2012-2015). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4593DOI Listing

Quantitative analysis of the expression of fluconazole-resistant genes in strains of Candida albicans isolated from elderly people at their admission in an intensive care unit in Manizales, Colombia

Biomedica 2020 03 1;40(1):153-165. Epub 2020 Mar 1.

Grupo de Investigación en Enfermedades Infecciosas, Universidad Católica de Manizales, Manizales, Colombia; Grupo de Resistencia Antibiótica de Manizales, Manizales, Colombia.

Introducción. Las infecciones oportunistas asociadas con Candida albicans han tenido gran repercusión en la salud pública por la mortalidad que generan en determinados grupos poblacionales. Aunque existen tratamientos farmacológicos disponibles, es evidente el aumento de la resistencia desarrollada por el agente patógeno, por lo que la determinación de los mecanismos de resistencia de las cepas presentes en las áreas hospitalarias es importante, ya que permitiría plantear mejores esquemas de tratamiento. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4723DOI Listing
March 2020
0.617 Impact Factor

Spatial analysis of PM2.5 concentrations in Bogotá according to the World Health Organization air quality guidelines for cardiopulmonary diseases, 2014-2015

Biomedica 2020 03 1;40(1):137-152. Epub 2020 Mar 1.

Maestría en Salud Pública, Universidad Santo Tomás, Bogotá, D.C, Colombia.

Introduction: The World Health Organization (WHO) points out that 3 million deaths per year caused by cardiopulmonary diseases are related to exposure to air pollution. Objective: To estimate areas of concentration of PM2.5 in Bogotá according to the WHO Air Quality Guidelines (AQG) for cardiopulmonary diseases during the period 2014-2015. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4719DOI Listing

Quality of life in patients with multiple sclerosis and their caregivers in Colombia: One-year follow-up.

Biomedica 2020 03 1;40(1):129-136. Epub 2020 Mar 1.

Unidad de Neurología, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.

Introduction: Multiple sclerosis is a chronic inflammatory demyelinating disease associated with neurological disability. Clinical features include motor, cerebellar, visual, and sensory function alterations, as well as psychiatric comorbidities, such as depression, anxiety, and irritability. There is little literature available on the quality of life of patients and their caregivers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4759DOI Listing

Concordance analysis of three diagnostic tests for malaria in the symptomatic population of Colombian endemic municipalities

Biomedica 2020 03 1;40(1):117-128. Epub 2020 Mar 1.

Grupo de Parasitología, Subdirección Laboratorio Nacional de Referencia, Dirección de Redes en Salud Pública, Instituto Nacional de Salud, Bogotá, D.C., Colombia.

Introduction: Taking into account the difficulty of performing malaria microscopic diagnosis in rural areas, rapid diagnostic tests (RDT) are a good alternative, but it is important to verify their diagnostic performance. Objective: To evaluate the diagnostic performance of the RDTs used in five Colombian departments by comparing them with the microscopic diagnosis and using PCR as the reference standard. Materials and methods: Thick blood film and RDTs were used to diagnose symptomatic individuals; additionally, the filter paper was impregnated with blood for the molecular test. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4893DOI Listing

The healthy aging phenotype in older people in Manizales

Biomedica 2020 03 1;40(1):102-116. Epub 2020 Mar 1.

Programa de Investigaciones en Gerontología y Geriatría, Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia.

Introduction: The healthy aging phenotype is present in those individuals that age with low morbidity, no functional or cognitive deterioration, and retain an acceptable level of wellness and social participation. Objective: To establish the frequency of the healthy aging phenotype in older people in the community using a multidimensional, a biomedical, and a psychosocial model and to identify the predicting factors in each model. Materials and methods: We conducted a cross-sectional, observational and descriptive study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4799DOI Listing

The delayed detection of an acute neurological worsening increases traumatic brain injury lethality

Biomedica 2020 03 1;40(1):89-101. Epub 2020 Mar 1.

Departamento de Medicina, Universidad del Norte, Barranquilla, Colombia.

Introduction: Traumatic brain injury is a leading worldwide cause of death and disability in young people. Severity classification is based on the Glasgow Coma Scale. However, the neurological worsening in an acute setting does not always correspond to the initial severity suggesting an underestimation of the real magnitude of the injury. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4786DOI Listing

Human olfactory mesenchymal stromal cells co-expressing horizontal basal and ensheathing cell proteins in culture.

Biomedica 2020 03 1;40(1):72-88. Epub 2020 Mar 1.

Unidad de Terapia Celular, Laboratorio de Patología Celular y Molecular, Centro de Medicina Experimental, Instituto Venezolano de Investigaciones Científicas, Caracas, Venezuela.

Introduction: The olfactory neuro-epithelium has an intrinsic capability of renewal during lifetime provided by the existence of globose and horizontal olfactory precursor cells. Additionally, mesenchymal stromal olfactory cells also support the homeostasis of the olfactory mucosa cell population. Under in vitro culture conditions with Dulbecco modified eagle/F12 medium supplemented with 10% fetal bovine serum, tissue biopsies from upper turbinate have generated an adherent population of cells expressing mainly mesenchymal stromal phenotypic markers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4762DOI Listing

Antimicrobial activity of endophytic fungi from the medicinal plants Mammea americana (Calophyllaceae) and Moringa oleifera (Moringaceae)

Biomedica 2020 03 1;40(1):55-71. Epub 2020 Mar 1.

Grupo de Investigación en Biotecnología, Agroambiente y Salud - Microbiota; maestría en Investigación de Enfermedades Infecciosas, Universidad de Santander, Bucaramanga, Colombia.

Introduction: Infectious diseases represent one of the leading causes of death worldwide. Considering the growing global challenge of antimicrobial resistance, research into new sources of potentially effective antimicrobial agents from natural origins is of great importance for world health. Objective: To evaluate the antimicrobial activity of endophytic fungi from Mammea americana and Moringa oleifera upon Staphylococcus aureus (ATCC 29213), S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4644DOI Listing

Vastus lateralis and medialis muscular activation during frontal and sagittal single-leg jumps in sportswomen

Biomedica 2020 03 1;40(1):43-54. Epub 2020 Mar 1.

Grupo de Movimiento Corporal Humano y Calidad de Vida, Universidad del Cauca, Popayán, Colombia.

Introduction: Differences in the lateral and medial portions from quadriceps muscular activation during the execution of the jump can become a neuromuscular risk factor raising knee dynamic valgus and increasing the risk for anterior cruciate ligament injury. Objective: To determine the difference in the activation of the lateral and medial vastus using surface electromyography during single-leg jumps in the sagittal and frontal plane in female athletes. Materials and methods: This was a quantitative, cross-sectional study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4938DOI Listing

Health status and barriers in health care for children with birth defects born between 2011 and 2017 in two institutions in Cali

Biomedica 2020 03 1;40(1):34-42. Epub 2020 Mar 1.

Grupo de Investigación en Ciencias Básicas y Clínicas de la Salud, Departamento de Ciencias Básicas de la Salud, Facultad de Ciencias de la Salud, Pontificia Universidad Javeriana, Cali, Colombia; Centro Médico Imbanaco, Cali, Colombia.

Introduction: Birth defects affect 2-3% of births contributing an important load to the causes of infant morbidity and mortality during the first five years of life. In Colombia, they are the second cause of infant mortality according to reports from the Departamento Administrativo Nacional de Estadística (DANE) 2011. Objective: To describe the state of health and barriers in the health care of children with congenital defects born between 2011 and 2017 in two institutions of Cali. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4906DOI Listing

Multiple brain abscesses due to Nocardia spp. in an immunocompetent patient

Biomedica 2020 03 1;40(1):27-33. Epub 2020 Mar 1.

Área de Radiología e Imágenes Diagnósticas, Hospital Universitario Mayor - Méderi, Bogotá, D.C., Colombia.

The infection by Nocardia spp is not common in immunocompetent patients. The empirical antimicrobial treatment directed by anatomical regions does not contemplate the particularities of the germ and the microbiological analysis is necessary for the specific treatment. We present the case of a previously healthy and immunocompetent patient, without known risk factors for Nocardia spp. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4925DOI Listing

A case of envenomation by the false fer-de-lance snake Leptodeira annulata (Linnaeus, 1758) in the department of La Guajira, Colombia.

Biomedica 2020 03 1;40(1):20-26. Epub 2020 Mar 1.

Grupo de Investigación en Proteínas, Departamento de Química, Universidad Nacional de Colombia, Bogotá, D.C., Colombia.

Envenomations by colubrid snakes in Colombia are poorly known, consequently, the clinical relevance of these species in snakebite accidents has been historically underestimated. Herein, we report the first case of envenomation by opisthoglyphous snakes in Colombia occurred under fieldwork conditions at the municipality of Distracción, in the department of La Guajira. A female biologist was bitten on the index finger knuckle of her right hand when she tried to handle a false fer-de-lance snake (Leptodeira annulata). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4773DOI Listing

Acute intermittent porphyria: A case report

Biomedica 2020 03 1;40(1):14-19. Epub 2020 Mar 1.

Escuela de Medicina, Universidad Pedagógica y Tecnológica de Colombia, Tunja, Colombia; Servicio de Medicina Interna, Hospital San Rafael, Tunja, Colombia.

The term ‘porphyria’ comes from the Greek ‘porphyra’. It refers to a heterogeneous group of metabolic disorders caused by the enzymatic deficiency in the biosynthesis of the heme group. Acute intermittent porphyria is caused by a deficiency of the porphobilinogen deaminase enzyme. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4767DOI Listing

The challenge of communicating and controlling the coronavirus epidemic

Biomedica 2020 Mar 1;40(1):11-13. Epub 2020 Mar 1.

Fundación Santa Fe de Bogotá; Editor asociado, Biomédica.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.5455DOI Listing

[Candida auris: estrategias y retos para prevenir un brote].

Biomedica 2020 Mar 1;40(1):5-10. Epub 2020 Mar 1.

Unidad de Micología Médica y Experimental, Corporación para Investigaciones Biológicas (CIB), Medellín, Colombia.

View Article

Download full-text PDF

Source

[Índices de evaluadores, autores y artículos 2019].

Biomedica 2019 Dec 1;39(4):821-833. Epub 2019 Dec 1.

.

View Article

Download full-text PDF

Source
December 2019

[Máncel Enrique Martínez Durán (1953-2019)].

Biomedica 2019 Dec 1;39(4):818-820. Epub 2019 Dec 1.

Departamento de Salud Pública, Universidad Nacional de Colombia, Bogotá, D.C., Colombia.

View Article

Download full-text PDF

Source
December 2019

Which should be the first-line treatment for Helicobacter pylori in Colombia? A lesson from a recent study.

Biomedica 2019 Dec 1;39(4):811-815. Epub 2019 Dec 1.

Unit of Gastroenterology, Molinette-SGAS Hospitals, Via Cavour 31, 10126 Turin, Turin 10123, Italy.

View Article

Download full-text PDF

Source
December 2019

[Autoría de regalo: elemento para NO considerar en una publicación].

Biomedica 2019 12 1;39(4):816-817. Epub 2019 Dec 1.

Grupo de Investigación UROGIV, Universidad del Valle, Cali, Colombia.

View Article

Download full-text PDF

Source
December 2019

Leptolegnia chapmanii como alternativa biológica para el control de Aedes aegypti

Biomedica 2019 12 1;39(4):798-810. Epub 2019 Dec 1.

Laboratorio de Hongos Entomopatógenos y Control Biológico, Centro de Estudios Parasitológicos y de Vectores (CEPAVE), Universidad Nacional de La Plata-CONICET, Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

Leptolegnia chapmanii is a facultative pathogen of many species of mosquitoes, among which species of the genus Aedes, Culex and Anopheles stand out for their medical and sanitary importance. The potential of L. chapmanii as an alternative to control lies in its virulence, pathogenicity and specificity against the larval stages of mosquitoes, and because of its harmlessness to non-target species such as fish and amphibians, among others. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4598DOI Listing
December 2019

First report of Aedes (Stegomyia) albopictus (Skuse) in Orinoquia region of Colombia

Biomedica 2019 12 1;39(4):785-797. Epub 2019 Dec 1.

Laboratorio de Entomología, Secretaría de Salud de Casanare, Yopal, Colombia.

Introducción. Aedes albopictus es vector de arbovirus, como Flavivirus, Alphavirus, Bunyavirus, Phlebovirus, Orbivirus y Picornavirus. Muchos son agentes etiológicos de enfermedades en humanos. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4344DOI Listing
December 2019

Trypanosoma cruzi infection in puerperal women and their neonates at Barcelona, Anzoategui State, Venezuela

Biomedica 2019 12 1;39(4):769-784. Epub 2019 Dec 1.

Posgrado en Biología Aplicada, Universidad de Oriente, Núcleo de Sucre, Cumaná, Venezuela.

Introduction. Trypanosoma cruzi is mainly transmitted by vectors. Other pathways such as oral and congenital transmission have become increasingly relevant. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4606DOI Listing
December 2019

Lipid-lowering drug prescriptions in a group of Colombian patients.

Biomedica 2019 12 1;39(4):759-768. Epub 2019 Dec 1.

Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia, Universidad Tecnológica de Pereira-Audifarma, S. A., Pereira, Colombia; Grupo de Investigación en Biomedicina, Fundación Universitaria Autónoma de las Américas, Pereira, Colombia.

Introduction: Lipid-lowering drugs, especially statins, have shown great relevance in preventing and treating cardiovascular diseases.

Objective: To determine the prescription patterns of lipid-lowering drugs and the variables associated with their use in a Colombian population.

Materials And Methods: This is a cross-sectional descriptive study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4801DOI Listing
December 2019

Frequency of emergency department visits and hospitalizations due to chronic obstructive pulmonary disease exacerbations in patients included in two models of care

Biomedica 2019 12 1;39(4):748-758. Epub 2019 Dec 1.

Departamento de Investigación, Fundación Neumológica Colombiana, Bogotá, D.C., Colombia.

Introduction: Exacerbations of chronic obstructive pulmonary disease (COPD) have a huge impact on lung function, quality of life and mortality of patients. Emergency Department visits and hospitalizations due to exacerbations cause a significant economic burden on the health system.

Objective: To describe the differences in the number of emergency visits and hospitalizations due to exacerbations of COPD among patients included in two models of care of the same institution. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4815DOI Listing
December 2019

Inequalities in health by regime of affiliation to the health system in events of obligatory notification, Colombia, 2015

Biomedica 2019 12 1;39(4):737-747. Epub 2019 Dec 1.

Observatorio Nacional de Salud, Instituto Nacional de Salud, Bogotá, D.C., Colombia.

Introduction: Inequalities in the health field are caused by the differences in the social and economic conditions, that influence the disease risk and the measures taken to treat the disease. Objective: We aimed to estimate the social inequalities in health in Colombia, according to the type of affiliation to the health system as a proxy of socioeconomic status. Materials and methods: We conducted a retrospective descriptive analysis calculating incidence rates age and sex adjusted for all mandatory reporting events using the affiliation regime (subsidized and contributory) as a socioeconomic proxy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4453DOI Listing
December 2019

Snakebite in the department of Nariño, Colombia: a retrospective analysis, 2008-2017

Biomedica 2019 12 1;39(4):715-736. Epub 2019 Dec 1.

Facultad de Ciencias Exactas y Naturales, Departamento de Biología, Grupo de Investigación en Ecología Evolutiva, Universidad de Nariño, Pasto, Colombia.

Introduction. Snakebite envenoming is a relevant public health problem, and, in Colombia, it was included as a mandatory notification event since 2004. Because it is a tropical country with great ecosystem diversity, it occupies third place in Latin America, after Mexico and Brazil, reaching the highest number of snakebites. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4830DOI Listing
December 2019

Extensively resistant tuberculosis, Colombia, 2006-2016

Biomedica 2019 12 1;39(4):707-714. Epub 2019 Dec 1.

Grupo de Micobacterias, Dirección Redes en Salud Pública, Instituto Nacional de Salud, Bogotá, D.C., Colombia.

Introducción. La tuberculosis extremadamente resistente a los medicamentos (TB-XDR) es el resultado de deficiencias en la administración del tratamiento y en la prevención de la transmisión de la enfermedad; además, es un reto para los programas nacionales de control de la tuberculosis. Objetivo. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4842DOI Listing
December 2019

Recovery of aerobic and anaerobic bacteria from patients with acute appendicitis using blood culture bottles

Biomedica 2019 12 1;39(4):699-706. Epub 2019 Dec 1.

Unidad de Prevención y Control de Infecciones, Hospital de San José, Bogotá, D.C., Colombia; Facultad de Medicina, Fundación Universitaria de Ciencias de la Salud, Bogotá, D.C., Colombia.

Introduction: Acute appendicitis is the first cause of acute abdomen, however, there is a little information about the associated bacteria and its sensibility profile. Objetive: To identify and to determine the resistance pattern of aerobic and anaerobic bacteria isolated in periapendicular fluid cultures taken in patients with acute appendicitis and to establish the proportions of isolates according to the clinical phase. Materials and methods: A descriptive and prospective study was undertaken at the Hospital Universitario de San José (Bogotá, Colombia) of patients older than sixteen years of age, undergoing an open appendectomy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4774DOI Listing
December 2019

Vagino-rectal colonization prevalence by Streptococcus agalactiae and its susceptibility profile in pregnant women attending a third-level hospital

Biomedica 2019 12 1;39(4):689-698. Epub 2019 Dec 1.

Departamento de Ginecología y Obstetricia, Hospital Universitario de Santander, Bucaramanga, Colombia.

Introduction: Streptococcus agalactiae is the main etiological agent causing invasive infection of the newborn with symptoms that may be associated with septicemia, pneumonia or meningitis and prevalences up to 50% worldwide where there is an increase in antibiotic resistance. Objective: To estimate the prevalence of vagino-rectal colonization by S. agalactiae and its sensitivity profile in pregnant women attending a third-level hospital. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7705/biomedica.4514DOI Listing
December 2019