1,382 results match your criteria Biomedica[Journal]


Inequalities on mortality due to acute respiratory infection in children: A Colombian analysis.

Biomedica 2018 Dec 1;38(4):586-593. Epub 2018 Dec 1.

Observatorio Nacional de Salud, Instituto Nacional de Salud, Bogotá, D.C., Colombia; Departamento de Gestión Organizacional, Universidad de la Costa, Barranquilla, Colombia.

Introduction: Acute respiratory infections (ARI) are a leading public health issue worldwide.

Objective: To explore the inequalities in ARI mortality rates in under-5, according to socioeconomic characteristics.

Materials And Methods: We conducted an ecological analysis to study inequalities at municipal level due to ARI mortality in children under 5 years. Read More

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https://www.revistabiomedica.org/index.php/biomedica/article
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http://dx.doi.org/10.7705/biomedica.v38i4.4062DOI Listing
December 2018
10 Reads

Calidad de vida y percepción de apoyo social en personas con HIV en Bogotá, Colombia.

Biomedica 2018 Dec 1;38(4):577-585. Epub 2018 Dec 1.

Grupo de Medicina Comunitaria, Universidad El Bosque, Bogotá, D.C., Colombia.

Introducción. En estudios llevados a cabo en países desarrollados se ha establecido que las personas con HIV/sida refieren tener una menos calidad de vida y menor apoyo social.Objetivo. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.3819DOI Listing
December 2018
1 Read

Percepción de diversos sectores sociales de Colombia sobre los biobancos con fines de investigación.

Biomedica 2018 Dec 1;38(4):569-576. Epub 2018 Dec 1.

Centro de Investigaciones, Fundación Cardiovascular de Colombia, Floridablanca, Colombia Centro de Investigaciones, Hospital Internacional de Colombia, Piedecuesta, Colombia Centro de Investigaciones, Fundación Universitaria - Fundación Cardiovascular de Colombia, Piedecuesta, Colombia.

Introducción. Los biobancos con fines de investigación son un bien público que necesita de la participación activa de todas las partes interesadas, por lo cual es importante conocer la percepción que tiene el público general en Colombia sobre su intervención en un biobanco.Objetivo. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.4327DOI Listing
December 2018
1 Read

Polimorfismos en los genes de la enzima alcohol deshidrogenasa (ADH1) y la citocromo P450 2E1 (CYP2E1) en pacientes con cirrosis y carcinoma hepatocelular.

Biomedica 2018 Dec 1;38(4):555-568. Epub 2018 Dec 1.

Grupo de Gastrohepatología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.

Introducción. Uno de los principales factores de riesgo del carcinoma hepatocelular es el consumo crónico de alcohol. En estudios en diferentes poblaciones, se sugiere que las variantes genéticas de las enzimas que participan en el metabolismo del alcohol, como la alcohol deshidrogenasa (ADH) y la citocromo P450 (CYP2E1), estarían asociadas con riesgo de enfermedades hepáticas terminales. Read More

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https://www.revistabiomedica.org/index.php/biomedica/article
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http://dx.doi.org/10.7705/biomedica.v38i4.3897DOI Listing
December 2018
8 Reads

Prevalencia de factores de riesgo cardiovascular en escolares de un área rural y de una urbana en Colombia.

Biomedica 2018 Dec 1;38(4):545-554. Epub 2018 Dec 1.

Fundación Cardioinfantil - Instituto de Cardiología, Bogotá, D.C., Colombia.

Introducción. Los factores de riesgo cardiovascular tienen su origen en la infancia. En diversos estudios, se han registrado diferencias en la prevalencia de tales factores entre las áreas rurales y las urbanas, probablemente asociadas con los estilos de vida. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.4223DOI Listing
December 2018
1 Read

Modelos potenciales de distribución geográfica y climática del complejo Amblyomma cajennense (Acari: Ixodidae), potencial vector de Rickettsia rickettsii en Colombia.

Biomedica 2018 Dec 1;38(4):534-544. Epub 2018 Dec 1.

Grupo de Investigación en Ciencias Veterinarias Centauro, Universidad de Antioquia, Medellín, Colombia.

Introducción. Las especies del complejo Amblyomma cajennense, potenciales vectores implicados en la transmisión de Rickettsia rickettsii en Centroamérica y Suramérica, presentan una amplia distribución geográfica en el neotrópico. En Colombia, todavía es incipiente el conocimiento sobre las especies de este complejo, su distribución y su ecología. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.3916DOI Listing
December 2018
1 Read

[Profile of antiretroviral agents use in Colombia].

Biomedica 2018 Dec 1;38(4):527-533. Epub 2018 Dec 1.

Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia, Universidad Tecnológica de Pereira, Audifarma, S. A., Pereira, Colombia.

Introduction: Since the beginning of the epidemic, human immunodeficiency virus (HIV) has taken more than 36 million lives.

Objective: To determine the antiretroviral drug prescription patterns in a population of individuals with HIV infection in Colombia.

Materials And Methods: Cross-sectional study analyzing the profiles of patients treated with antiretroviral drugs between April 1st and September 30th, 2015. Read More

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https://www.revistabiomedica.org/index.php/biomedica/article
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http://dx.doi.org/10.7705/biomedica.v38i4.3885DOI Listing
December 2018
11 Reads

Puntos de corte provisionales para el diagnóstico de sarcopenia en ancianos de Caldas, Colombia.

Biomedica 2018 Dec 1;38(4):521-526. Epub 2018 Dec 1.

Grupo de Investigación en Bioimpedancia Eléctrica, Universidad de Caldas, Manizales, Colombia Grupo de Investigación en Gerontología y Geriatría, Universidad de Caldas, Manizales, Colombia.

Introducción. La sarcopenia es la disminución de masa muscular y la consecuente reducción del rendimiento y de la función física. Su aparición puede ser indicativa de riesgo de otras condiciones en los ancianos, y su diagnóstico requiere la comparación con los datos sobre la composición corporal de la población joven sana para establecer valores de referencia de la disminución de la masa muscular. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.4302DOI Listing
December 2018
2 Reads

[Frecuencia de las reacciones alérgicas a la vacuna triple viral en pacientes con alergia al huevo].

Biomedica 2018 Dec 1;38(4):514-520. Epub 2018 Dec 1.

Grupo de Alergología Clínica y Experimental, IPS Universitaria, Universidad de Antioquia, Medellín, Colombia Fundación para el Desarrollo de las Ciencias Médicas y Biológicas (FUNDEMEB), Cartagena, Colombia Instituto de Investigaciones Inmunológicas, Universidad de Cartagena, Cartagena, Colombia.

Introducción. La vacunación es la intervención en salud pública más efectiva de todos los tiempos, pues reduce la mortalidad y la morbilidad de múltiples enfermedades infecciosas. En muchas ocasiones, la aplicación de las vacunas se retrasa por el temor a las reacciones alérgicas, lo cual es frecuente entre los pacientes con alergia al huevo que requieren la vacuna triple viral (rubeola-sarampión-parotiditis). Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.3779DOI Listing
December 2018
1 Read

Actividad in vitro del tedizolid y de antibióticos de comparación en aislamientos de Staphylococcus aureus resistentes a meticilina en infecciones de piel y tejidos blandos en siete hospitales de Colombia.

Biomedica 2018 Dec 1;38(4):507-513. Epub 2018 Dec 1.

Departamento de Microbiología, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, D.C., Colombia Grupo para el Control de la Resistencia Bacteriana de Bogotá, Grebo, Bogotá, D.C., Colombia Departamento de Patología y Laboratorios, Fundación Santa Fe de Bogotá, Bogotá, D.C., Colombia Departamento de Medicina Interna, Fundación Santa Fe de Bogotá, Bogotá, D.C., Colombia.

Introducción. Staphylococcus aureus resistente a meticilina (SARM) causa infecciones graves de la piel y los tejidos blandos en los hospitales y, en los últimos años, en la comunidad. El tedizolid es una nueva oxazolidinona cuya potencia in vitro ha demostrado ser mayor que la del linezolid frente a este microorganismo. Read More

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https://www.revistabiomedica.org/index.php/biomedica/article
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http://dx.doi.org/10.7705/biomedica.v38i4.4022DOI Listing
December 2018
2 Reads

[Effects of exercise on the cognition of older women treated with lovastatin].

Biomedica 2018 Dec 1;38(4):496-506. Epub 2018 Dec 1.

Departamento de Educación Física, Universidad Metropolitana de Ciencias de la Educación, Santiago de Chile, Chile.

Introduction: The deterioration of cognition is highly predominant in older adults.

Objective: The aim of this study was to analyze the effects of a walking program on the cognition and blood concentration of lipids in women over 60 years of age who were being treated with lovastatin.

Materials And Methods: Participants were distributed in two groups: An exercise group (EG, n=45) with aerobic training and an inactive sedentary group (SG, n=22). Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.4262DOI Listing
December 2018
2 Reads

Evaluación de la intercambiabilidad in vitro de diferentes marcas de tabletas de diclofenaco sódico disponibles en el mercado colombiano.

Biomedica 2018 Dec 1;38(4):486-495. Epub 2018 Dec 1.

Grupo de Investigación en Sistemas para la Liberación Controlada de Moléculas Biológicamente Activas, Departamento de Farmacia, Facultad de Ciencias, Universidad Nacional de Colombia, Bogotá, D.C., Colombia.

Introducción. El diclofenaco sódico se clasifica como un antiinflamatorio no esteroide. Dado que es de venta libre, el paciente no tiene ningún seguimiento por parte de los equipos de salud, y como sus fuentes son múltiples, es necesario establecer la equivalencia entre ellas en estudios in vitro, que son los más prácticos y plantean un menor compromiso ético. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.3988DOI Listing
December 2018
1 Read

[Efecto de un enfoque estandarizado para el manejo de lactantes hospitalizados por eventos aparentemente letales].

Biomedica 2018 Dec 1;38(4):479-485. Epub 2018 Dec 1.

Departamento de Pediatría, Facultad de Medicina, Universidad de Concepción, Concepción, Chile Servicio de Pediatría, Hospital Guillermo Grant Benavente, Concepción, Chile.

Introducción. Los eventos aparentemente letales (Apparent Life-Threatening Event, ALTE) son causa frecuente de hospitalización en lactantes. Hay poca información sobre el enfoque estandarizado para establecer su etiología, a pesar de que un diagnóstico causal correcto puede afectar la evolución clínica, la duración de la hospitalización y los recursos sanitarios. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.3754DOI Listing
December 2018
1 Read

Evaluación de la exposición al polvo de carbón y de sílice en sitios de minería subterránea en tres departamentos de Colombia.

Biomedica 2018 Dec 1;38(4):467-478. Epub 2018 Dec 1.

Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, D.C., Colombia.

Introducción. La neumoconiosis de mineros del carbón es una enfermedad crónica e irreversible que se considera un problema de salud pública.Objetivo. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.4183DOI Listing
December 2018
1 Read

Síndrome epiléptico ligado al cromosoma X por mutación de la protocaderina 19 (OMIM 300088) asociado con leucoencefalopatía y tractopatía posterior reversible.

Biomedica 2018 Dec 1;38(4):463-466. Epub 2018 Dec 1.

Grupo de Neurología Infantil, Universidad de Antioquia, Medellín, Colombia.

La epilepsia con retardo mental ligado al cromosoma X por mutación del gen PCDH19, es una condición que solo se presenta en las mujeres. El cuadro clínico suele verse complicado con retardo global del desarrollo y epilepsia. En la edad adulta puede manifestarse con discapacidad intelectual y hasta 20 % de las mujeres afectadas no presentan convulsiones ni retardo intelectual. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.3900DOI Listing
December 2018
1 Read

[Glomerulonefritis colapsante con marcadores de desdiferenciación podocitaria en síndrome hemofagocítico secundario a linfoma hepatoesplénico de células T].

Biomedica 2018 Dec 1;38(4):456-462. Epub 2018 Dec 1.

Unidad de Nefrología, Hospital de Poniente, El Ejido, España.

El síndrome hemofagocítico es una condición clínica e histológica grave, secundaria a diferentes procesos. La glomerulonefritis colapsante es una podocitopatía proliferativa, generalmente de pronóstico desfavorable para la función renal. Se presenta un caso en el que las dos condiciones aparecieron asociadas, lo cual es una forma infrecuente de presentación del linfoma hepatoesplénico de células T. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.3893DOI Listing
December 2018
2 Reads

[Control integrado de garrapatas y su importancia en salud pública].

Biomedica 2018 Dec 1;38(4):452-455. Epub 2018 Dec 1.

Laboratorio de Parasitología Veterinaria, Departamento de Salud Animal, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogotá, D. C., Colombia.

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December 2018
2 Reads

Levels of physical activity, health-related quality of life, physical self-concept and body-mass index among Colombian students

Biomedica 2018 Sep 1;38(3):451-452. Epub 2018 Sep 1.

Departamento de Pediatría, Universidad del Valle, Cali, Colombia.

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http://dx.doi.org/10.7705/biomedica.v38i3.4746DOI Listing
September 2018

A new theory of depression based on the serotonin/kynurenine relationship and the hypothalamicpituitary- adrenal axis

Biomedica 2018 09 1;38(3):437-450. Epub 2018 Sep 1.

Departamento de Neurociencias, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi", Universidad Autónoma de Yucatán, Mérida, México.

The serotonergic and immunological hypothesis of depression proposes that certain types of excessive stress distort the relationship between the activities of the innate immune and central nervous systems, so that the stress caused by an infection, or excessive psychological stress, activate toll-like receptors such as the TLR-4, the transcription factor NF-kB, the inflammasome NLRP3, as well as the secretion of interleukin-1 beta (IL-1β), interleukin-6 (IL-6) and other factors of the innate immune response, causing first, the general symptoms of the disease which appear with any infection, but also those characteristic of depressive illness such as dysphoria and anhedonia. The evidence indicates that, if the stimulus persists or recurs within 24 hours, the indole-2, 3-dioxygenase enzyme (IDO) of the kynurenine metabolic pathway, which increases the synthesis of quinolinic acid, is activated with an associated reduction of serotonin synthesis. Quinolinic acid activates NMDA receptors in the central nervous system and stimulates the secretion of interleukins IL-6 and 1L-1β, among others, promoting hyper-activity of the HPA axis and reinforcing a bias of the tryptophan metabolism to produce quinolinic acid, and interleukins by the innate immune system, further reducing the synthesis of serotonin and consolidating the depressive process. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3688DOI Listing
September 2018
17 Reads
0.620 Impact Factor

Serum adipokine levels and insulin resistance in the first trimester of pregnancy in adolescents and their relationship with neonatal weight

Biomedica 2018 09 1;38(3):427-436. Epub 2018 Sep 1.

Grupo de Cuidado Materno Perinatal, Facultad de Enfermería, Universidad Nacional de Colombia, Bogotá, D.C., Colombia División de Lípidos y Diabetes, Departamento de Ciencias Fisiológicas, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, D.C., Colombia.

Introduction: The approach to the physiology of pregnancy based on adipokine behavior and the homeostasis-insulin resistance (HOMA-IR) model, along with their relationship to neonatal weight, has been poorly studied in adolescent pregnant women. Objective: To determine possible correlations between adipokines –leptin and adiponectin– and HOMA-IR in pregnant women aged 14 to 17 years, and first-trimester body mass index (BMI) and neonatal weight. Materials and methods: In the weeks 11 to 14 of gestation, the biochemical variables leptin, adiponectin, glycemia and insulin were measured and HOMA-IR was calculated. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.4035DOI Listing
September 2018
5 Reads

[Prescribing patterns of antiparkinson drugs in a group of Colombian patients, 2015].

Biomedica 2018 09 1;38(3):417-426. Epub 2018 Sep 1.

Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia, Universidad Tecnológica de Pereira-Audifarma, S.A., Pereira, Colombia.

Introduction: Parkinson's disease, whose prevalence in Colombia is 4.7 per 1,000 inhabitants, is a public health problem and a therapeutic challenge for health professionals.

Objective: To determine the prescribing patterns of antiparkinson drugs and the variables associated with its use in a population from Colombia. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.3781DOI Listing
September 2018
1 Read

Characterization of potential drug-drug interactions in patients hospitalized in the intensive care unit of a tertiary hospital in Bogotá

Biomedica 2018 09 1;38(3):407-416. Epub 2018 Sep 1.

Departamento de Farmacología Clínica y Terapéutica, Universidad de La Sabana, Chía, Colombia.

Introduction: Drug-drug interactions occur more frequently in intensive care units than in other services. However, in Colombia, there are few studies on this problem in critically ill patients. Objectives: To characterize potential drug-drug interactions generated from prescriptions during hospitalization in an intensive care unit and to determine factors associated with their onset. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.3884DOI Listing
September 2018
2 Reads

Drug utilization study of two generic antibiotics in a tertiary hospital in Bogotá

Biomedica 2018 09 1;38(3):398-406. Epub 2018 Sep 1.

Grupo de Investigación de la Red para el Uso Adecuado de Medicamentos, Departamento de Farmacia, Facultad de Ciencias, Universidad Nacional de Colombia, Bogotá, D.C., Colombia.

Introduction: The Colombian national pharmaceutical policy establishes as a strategy the generation of greater pharmaco-epidemiological research at the national level, especially in the case of antibiotic drugs. Objective: To provide local pharmaco-epidemiological evidence regarding the effectiveness, conditions of use and safety of generic meropenem and cefepime in a tertiary hospital in Bogotá. Materials and methods: We conducted a descriptive, longitudinal and retrospective drug utilization study. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.3831DOI Listing
September 2018
2 Reads

[Neurogenesis and gliogenesis modulation in cerebral ischemia by CDK5 RNAi-based therapy].

Biomedica 2018 09 1;38(3):388-397. Epub 2018 Sep 1.

Grupo de Neurociencias de Antioquia, Área de Neurobiología Celular y Molecular, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.

Introduction: Cerebral ischemia is the third cause of death risk in Colombia and the first cause of physical disability worldwide. Different studies on the silencing of the cyclin-dependent kinase 5 (CDK5) have shown that reducing its activity is beneficial in ischemic contexts. However, its effect on neural cell production after cerebral ischemia has not been well studied yet. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.3800DOI Listing
September 2018
8 Reads

Flow cytometry in peripheral blood reticulocytes as a marker of chromosome instability in highgrade glioma patients

Biomedica 2018 09 1;38(3):379-387. Epub 2018 Sep 1.

Grupo de Genética, Regeneración y Cáncer (GRC), Instituto de Biología, Universidad de Antioquia, Medellín, Colombia.

Introduction: The quantification of chromosomal instability is an important parameter to assess genotoxicity and radiosensitivity. Most conventional techniques require cell cultures or laborious microscopic analyses of chromosomes or nuclei. However, a flow cytometry that selects the reticulocytes has been developed as an alternative for in vivo studies, which expedites the analytical procedures and increases up to 20 times the number of target cells to be analyzed. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.3882DOI Listing
September 2018
1 Read

Immediate versus delayed breast reconstruction in breast cancer patients in Colombia: A costutility analysis

Biomedica 2018 09 1;38(3):363-378. Epub 2018 Sep 1.

Servicio de Anestesiología, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.

Introduction. Breast reconstruction, either immediate or delayed, is part of the treatment of breast cancer. Each country and health system pays for and evaluates these procedures in different ways. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3705DOI Listing
September 2018
18 Reads

Feeding in adults with type II diabetes mellitus in three public hospitals in Cundinamarca, Colombia

Biomedica 2018 09 1;38(3):355-362. Epub 2018 Sep 1.

Grupo de Nutrición, Subdirección de Investigación Científica y Tecnológica, Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, D.C., Colombia.

Introduction: Type II diabetes mellitus (DMII) is one of the main causes of morbidity and mortality both worldwide and in Colombia. It mainly affects men and women over 45 years of age. Inadequate control of this disease can generate greater health complications making it one of the most costly diseases in the country. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3816DOI Listing
September 2018

[Full-term low birth weight and its relationship with the socioeconomic conditions of municipalities in Antioquia: Spatio-temporal analysis].

Biomedica 2018 09 1;38(3):345-354. Epub 2018 Sep 1.

Grupo de Investigación en Determinantes Sociales de la Salud y la Nutrición, Universidad de Antioquia, Medellín, Colombia.

Introduction: Low birth weight is one of the main health predictors for childhood and adulthood. It is highly prevalent in developing countries and in children from poorer social classes.

Objective: To analyze the geographical distribution and the trends of full-term low birth weight in the 125 municipalities of the department of Antioquia and their association with the socioeconomic conditions of the municipalities between 2000 and 2014. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3734DOI Listing
September 2018
2 Reads

Isolation of Bacillus cereus in school restaurants in Colombia

Biomedica 2018 09 1;38(3):338-344. Epub 2018 Sep 1.

Grupo de Nutrición, Subdirección de Investigación Científica y Tecnológica, Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, D.C., Colombia.

Introduction: Bacillus cereus is recognized as a pathogen that causes food poisoning. It is a facultative aerobic metabolism bacterium capable of forming spores, which allows it to survive pasteurization and heating even by the gamma irradiation used to reduce pathogens in food. Objective: To study the presence of Bacillus cereus and its diarrheal toxin in rice and ready-to-eat cereals, flours, and starches in school restaurants in Colombia. Read More

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https://www.revistabiomedica.org/index.php/biomedica/article
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http://dx.doi.org/10.7705/biomedica.v38i3.3802DOI Listing
September 2018
1 Read

Classical HLA alleles tag SNP in families from Antioquia with type 1 diabetes mellitus

Biomedica 2018 09 1;38(3):329-337. Epub 2018 Sep 1.

Grupo de Mapeo Genético, Departamento de Pediatría, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.

Introduction: The HLA region strongly associates with autoimmune diseases, such as type 1 diabetes. An alternative way to test classical HLA alleles is by using tag SNP. A set of tag SNP for several classical HLA alleles has been reported as associated with susceptibility or resistance to this disease in Europeans. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3768DOI Listing
September 2018
3 Reads

JAG1, MEF2C and BDNF polymorphisms associated with bone mineral density in women from Northern México

Biomedica 2018 09 1;38(3):320-328. Epub 2018 Sep 1.

Centro de Investigación en Nutrición y Salud Pública, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.

Introduction: Osteoporosis is characterized by a low bone mineral density. Genetic composition is one of the most influential factors in determining bone mineral density (BMD). There are few studies on genes associated with BMD in the Mexican population. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.4014DOI Listing
September 2018

A pathogenic homozygous variant of the BBS10 gene in a patient with Bardet Biedl syndrome

Biomedica 2018 09 1;38(3):308-320. Epub 2018 Sep 1.

Departamento de Genética, Grupo de Investigación GenHOMI, Fundación Hospital Pediátrico La Misericordia-HOMI, Bogotá, D.C., Colombia Maestría en Genética Humana, Universidad Nacional de Colombia, Bogotá, D.C., Colombia.

The Bardet-Biedl syndrome is an autosomal recessive hereditary disorder with vast locus heterogeneity that belongs to the so-called ciliopathies, whose proteins are localized in the primary cilia and present functional deficiency. The multisystemic features of the disease include ocular, renal, cognitive, skeletal, as well as gonadal involvement and obesity, among others, with high inter- and intrafamilial variability. We describe the clinical case of an adolescent male patient with Bardet-Biedl syndrome, including the approach, the results from a 22-gene sequencing panel, and the analysis of updated scientific literature. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.4199DOI Listing
September 2018
22 Reads

Myoclonus induced by salbutamol: A case report

Biomedica 2018 09 1;38(3):303-307. Epub 2018 Sep 1.

Centro de Información y Estudio de Medicamentos y Tóxicos, Departamento de Farmacología y Toxicología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.

Salbutamol is a β2 adrenergic agonist widely prescribed in patients with obstructive and restrictive lung diseases. The main side effects associated with its use are tachycardia and tremor. Myoclonus is an involuntary, irregular, abrupt, brief and sudden muscular contraction, which can be generalized, focal or multifocal. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3813DOI Listing
September 2018
4 Reads
0.620 Impact Factor

Disseminated histoplasmosis as a first clinical manifestation in a patient with small lymphocytic lymphoma: A case report

Biomedica 2018 09 1;38(3):298-302. Epub 2018 Sep 1.

Departamento de Hemato-Patología, Fundación Valle del Lili, Cali, Colombia.

The small lymphocytic lymphoma is a mature B cell neoplasm with a broad spectrum of clinical presentations. Opportunistic infections that are not related to the treatment, even in advanced stages, have a low incidence rate. There are few case reports in the medical literature of patients who have not received immunosuppressive therapy and present with small lymphocytic lymphoma associated with disseminated histoplasmosis at diagnosis. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3739DOI Listing
September 2018
13 Reads

Genetic polymorphism in Colombian populations and its importance for public health

Biomedica 2018 Sep 1;38(3):295-297. Epub 2018 Sep 1.

Genética Clínica, Departamento de Biociencias, Universidad de La Sabana, Chía, Colombia.

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September 2018
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Cutaneous leishmaniasis and pregnancy

Biomedica 2018 Aug 1;38(0):144-146. Epub 2018 Aug 1.

Facultad de Medicina, Universidad de La Sabana

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In vitro culture of L3 larvae of nematodes obtained from the African giant snail Lissachatina fulica (Mollusca: Gastropoda) in Santa Fe de Antioquia.

Biomedica 2018 Aug 1;38(0):24-29. Epub 2018 Aug 1.

Grupo de Microbiología Ambiental, Escuela de Microbiología, Universidad de Antioquia, Medellín, Colombia.

Introduction: Over 170 municipalities in Colombia have been invaded by Lissachatina fulica, an African snail that can carry larvae of nematodes of interest in human and veterinary health. Nematodes enter the host snail as larvae L1 and then change to L2 and L3, the infectious form for vertebrates.

Objective: To standardize culture in vitro of L3 carried by L. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3408DOI Listing
August 2018
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Severe disseminated acute toxoplasmosis in an adult immunocompetent patient from the Colombian Pacific

Biomedica 2018 08 1;38(0):19-23. Epub 2018 Aug 1.

Facultad de Salud, Departamento de Patología, Universidad del Valle, Cali, Colombia.

We present the case of a 72-year-old immunocompetent patient from Chocó, Colombia, with a 12-day course of fever, headache, progressive neurological deterioration, and rapid evolution to multiorgan failure and death. In the histopathological study of tissues obtained at necropsy, tissue cysts morphologically suggestive of being bradyzoites of Toxoplasma gondii were identified and confirmed by immunohistochemistry in heart, brain, and striated muscle. Read More

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http://dx.doi.org/10.7705/biomedica.v38i0.4087DOI Listing
August 2018
1 Read

Microcephaly in Colombia before the Zika outbreak: A systematic literature review.

Biomedica 2018 Aug 1;38(0):127-134. Epub 2018 Aug 1.

Centro de Investigaciones en Anomalías Congénitas y Enfermedades Raras, Universidad Icesi, Cali, Colombia Biomaterials and Tissues Engineering, University College London, London, United Kingdom.

Introduction: Microcephaly is characterized by a smaller than normal head circumference. Recently, Zika virus (ZV) has been associated with microcephaly.

Objective: To describe the prevalence of microcephaly in Colombia taking as the baseline the information from the period before the Zika virus infection epidemics. Read More

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http://dx.doi.org/10.7705/biomedica.v38i0.4413DOI Listing

Genetic diversity and population structure of Anopheles triannulatus s. l. in the department of Córdoba, Colombia, using DNA barcoding

Biomedica 2018 08 1;38(0):117-126. Epub 2018 Aug 1.

Grupo de Investigaciones en Enfermedades Tropicales y Resistencia Bacteriana, Universidad del Sinú, Montería, Colombia.

Introduction: Anopheles triannulatus is not incriminated as a vector of malaria transmission in Colombia despite recent reports of infection with Plasmodium spp. in populations related to the northwestern and southeastern lineages. Genetic diversity can delimit information about gene flow and population differentiation in localities with malaria. Read More

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https://www.revistabiomedica.org/index.php/biomedica/article
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http://dx.doi.org/10.7705/biomedica.v38i0.4055DOI Listing
August 2018
4 Reads

Knowledge, practices and entomological aspects of dengue in Medellín, Colombia: A comparative study of neighborhoods with high and low incidence

Biomedica 2018 08 1;38(0):106-116. Epub 2018 Aug 1.

Grupo de Entomología Médica, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.

Introduction: Dengue, mainly transmitted by Aedes aegypti, is a very important viral disease in terms of public health. Colombia is an endemoepidemic country for dengue and, in cities like Medellín, there are neighborhoods with high and low incidence. The disease dynamics in the neighborhoods might be determined by differences in the knowledge, practices and entomological aspects of the vector among the communities. Read More

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http://dx.doi.org/10.7705/biomedica.v38i0.3957DOI Listing
August 2018
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Novel larvicide tablets of Bacillus thuringiensis var. israelensis: Assessment of larvicidal effect on Aedes aegypti (Diptera: Culicidae) in Colombia.

Biomedica 2018 Aug 1;38(0):95-105. Epub 2018 Aug 1.

Instituto Colombiano de Medicina Tropical-Universidad CES, Sabaneta, Colombia.

Introduction: Aedes (Stegomyia) aegypti is the vector for dengue, chikungunya, and Zika arboviruses. Bti-CECIF is a bioinsecticide designed and developed in the form of a solid tablet for the control of this vector. It contains Bacillus thuringiensis var. Read More

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http://dx.doi.org/10.7705/biomedica.v38i0.3940DOI Listing
August 2018
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Mycobacterioses identified in the National Reference Laboratory of Colombia from 2012 to 2016

Biomedica 2018 08 1;38(0):87-94. Epub 2018 Aug 1.

Grupo de Micobacterias, Laboratorio Nacional de Referencia, Instituto Nacional de Salud, Bogotá, D.C., Colombia.

Introduction: In recent years, there has been an increase in the prevalence of mycobacterioses caused by non-tuberculous mycobacteria, which are considered as emerging pathogens. Their presence depends on several factors such as the clinical history, the health status of the affected person, and the presence of these microorganisms in the water, the soil, and the animals, among others. Objective: To describe the mycobacteria and the etiological agent identified in isolates received at the Laboratorio Nacional de Referencia de Micobacterias of the Instituto Nacional de Salud between 2012 and 2016. Read More

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http://dx.doi.org/10.7705/biomedica.v38i0.4143DOI Listing
August 2018
18 Reads

[Nuclei ultrastructural changes of C6/36 cells infected with virus dengue type 2].

Biomedica 2018 08 1;38(0):135-143. Epub 2018 Aug 1.

Grupo de Morfología Celular, Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, D.C., Colombia.

Introduction: Dengue virus replication has been considered mainly cytoplasmic, however, studies indicate that some flaviviruses may use the intranuclear pathway as part of the machinery that the virus uses to increase infection capacity in the host cell. This paper describes alterations at nuclear level in the cell infected with dengue, which are likely involved in the virus replication processes.

Objective: This paper addresses the ultrastructural observations of C6/36 cells of the Aedes albopictus mosquito infected with dengue virus type 2. Read More

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http://dx.doi.org/10.7705/biomedica.v38i0.3997DOI Listing
August 2018
3 Reads

[First report of Dioctophyma renale (Nematoda, Dioctophymatidae) in Colombia].

Biomedica 2018 08 1;38(0):13-18. Epub 2018 Aug 1.

Facultad de Ciencias Exactas, Naturales y Agropecuarias, Programa de Medicina Veterinaria, Laboratorio de Parasitología, Universidad de Santander, Bucaramanga, Colombia.

Dioctophymosis is a zoonotic parasitic disease caused by Dioctophyma renale (Goeze, 1782). It is distributed worldwide and it affects a large number of wild and domestic mammals.Here we report the first confirmed case of canine dioctophymosis in Colombia. Read More

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https://www.revistabiomedica.org/index.php/biomedica/article
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http://dx.doi.org/10.7705/biomedica.v38i4.4042DOI Listing
August 2018
3 Reads

Exposure and sensitization to insects in allergic patients in the tropics

Biomedica 2018 08 1;38(0):80-86. Epub 2018 Aug 1.

Grupo de Alergología Clínica y Experimental, IPS Universitaria, Universidad de Antioquia, Medellín, Colombia Fundación para el Desarrollo de las Ciencias Médicas y Biológicas, Cartagena, Colombia.

Introduction: Mites are an important source of allergens in the tropics. Other potential sources of allergens prevalent in the region such as insects have been poorly studied. Objective: To determine the relationship between exposure and allergic sensitization to cockroaches, mosquitos, ants and the interaction with mite sensitization. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3801DOI Listing
August 2018
3 Reads

Tuberculosis and human immunodeficiency virus coinfection: Epidemiological situation in the department of Meta, 2010- 2015

Biomedica 2018 08 1;38(0):68-79. Epub 2018 Aug 1.

Facultad de Ciencias de la Salud, Universidad de los Llanos, Villavicencio, Colombia.

Introduction. One third of the increase in tuberculosis cases is attributed to the spread of HIV. Objective. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3930DOI Listing
August 2018
1 Read

[Current characteristics of tuberculosis and human immunodeficiency virus co-infection in a cohort of hospitalized patients in Medellín, Colombia].

Biomedica 2018 08 1;38(0):59-67. Epub 2018 Aug 1.

Grupo Investigador de Problemas en Enfermedades Infecciosas, Facultad de Medicina, Sede de Investigación Universitaria, Universidad de Antioquia, Medellín, Colombia.

Introduction: Tuberculosis (TB) is an important cause of morbidity and mortality in HIV patients. It is unknown if the advent of molecular diagnostic methods and a greater availability of antiretroviral therapy (ART) in our country have changed some characteristics of the TB/HIV co-infection.

Objective: To describe the epidemiology, clinical features, diagnosis, resistance patterns, tuberculosis drug effects and mortality in co-infected patients. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3862DOI Listing
August 2018
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Molecular detection of pathogenic Leptospira in synanthropic and wild rodents captured in Yucatán, México

Biomedica 2018 08 1;38(0):51-58. Epub 2018 Aug 1.

Laboratorio de Enfermedades Emergentes y Reemergentes, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi", Universidad Autónoma de Yucatán, Mérida, México.

Introduction: Leptospirosis is a zoonotic disease caused by bacteria of the genus Leptospira, which is endemic in México and considered a public and veterinary health problem. Rodents are the most relevant reservoirs of Leptospira spp. because the bacteria establish and reproduce in its renal tissue and are excreted through the urine. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3938DOI Listing
August 2018
6 Reads

Genetic variability in coding regions of the surface antigen and reverse transcriptase domain of hepatitis B virus polymerase, Colombia, 2002-2014

Biomedica 2018 08 1;38(0):37-50. Epub 2018 Aug 1.

Laboratorio de Virología, Subdirección de Laboratorio Nacional de Referencia, Dirección de Redes en Salud Pública, Instituto Nacional de Salud, Bogotá, D.C., Colombia.

Introduction: Despite the availability of an effective vaccine and treatment to reduce the viral load and progressive hepatocellular injury, approximately 240 million people worldwide are chronically infected with the hepatitis B virus (HBV). In Colombia, the circulation of different viral genotypes has been confirmed. Mutations in the genome have been associated to antiviral therapy resistance, viral escape to neutralizing antibodies, occult infection and progression to hepatocellular carcinoma. Read More

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http://dx.doi.org/10.7705/biomedica.v38i3.3871DOI Listing
August 2018
6 Reads