15,730 results match your criteria Biomed Res Int[Journal]


Applicability of Smartphone for Dynamic Postural Stability Evaluation.

Biomed Res Int 2019 20;2019:9753898. Epub 2019 Mar 20.

Faculty of Physical Education, The Jerzy Kukuczka Academy of Physical Education in Katowice, Katowice, Poland.

The purpose of this study was to determine the accuracy of smartphone's gyroscope for dynamic postural stability among young healthy adults. The research included convenience sample of 85 healthy adults-37 women (mean age 22.1±1. Read More

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http://dx.doi.org/10.1155/2019/9753898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446100PMC

Clinical and Radiological Outcomes of Anterior Approach Microscopic Surgery for the Pincer Mechanism in Cervical Spondylotic Myelopathy.

Biomed Res Int 2019 20;2019:9175234. Epub 2019 Mar 20.

Department of Neurosurgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, China.

Objective: We aimed to evaluate the efficacy of anterior approach microscopic surgery for patients with the pincer mechanism in cervical spondylotic myelopathy.

Methods: The clinical data of pincer cervical spondylotic myelopathy that received anterior cervical decompression and fusion in our hospital from Aug 2014 to Dec 2017 were analyzed retrospectively, including 12 males and 9 females, with an average age of 64.3 years (range 46-81 years). Read More

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http://dx.doi.org/10.1155/2019/9175234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446116PMC

Efficacy Evaluation and Tracking of Bone Marrow Stromal Stem Cells in a Rat Model of Renal Ischemia-Reperfusion Injury.

Biomed Res Int 2019 20;2019:9105768. Epub 2019 Mar 20.

Imaging Department, First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province 030001, China.

Objectives: The aim of this study was to evaluate the effects of bone marrow stromal stem cells (BMSCs) on renal ischemia-reperfusion injury (RIRI) and dynamically monitor engrafted BMSCs in vivo for the early prediction of their therapeutic effects in a rat model.

Methods: A rat model of RIRI was prepared by clamping the left renal artery for 45 min. One week after renal artery clamping, 2 × 10 superparamagnetic iron oxide- (SPIO-) labeled BMSCs were injected into the renal artery. Read More

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http://dx.doi.org/10.1155/2019/9105768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446097PMC

Potential Role of lncRNA H19 as a Cancer Biomarker in Human Cancers Detection and Diagnosis: A Pooled Analysis Based on 1585 Subjects.

Biomed Res Int 2019 19;2019:9056458. Epub 2019 Mar 19.

Department of Urology, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen 518000, China.

Long noncoding RNAs (lncRNAs) have been reported to serve as diagnostic and prognostic biomarkers of cancers, which play vital roles in tumorigenesis and tumor progression. Several studies have been performed to explore diagnostic value of lncRNA H19 in cancer detection and diagnosis. However, there are still inconsistent results in diagnostic accuracy and reliability in individual studies. Read More

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http://dx.doi.org/10.1155/2019/9056458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444267PMC

Effects of Resveratrol on the Mechanisms of Antioxidants and Estrogen in Alzheimer's Disease.

Biomed Res Int 2019 20;2019:8983752. Epub 2019 Mar 20.

Department of Science and Technology, Guangdong Medical University, Dongguan 523808, Guangdong, China.

Objective: To observe the effects of resveratrol (Res) on the antioxidative function and estrogen level in an Alzheimer's disease (AD) mouse model.

Methods: First, we examined the effects of Res on an AD mice model. SAMP8 mice were selected as the model, and normal-aging SAMR1 mice were used as the control group. Read More

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http://dx.doi.org/10.1155/2019/8983752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446083PMC

Pulmonary Rehabilitation for Exercise Tolerance and Quality of Life in IPF Patients: A Systematic Review and Meta-Analysis.

Biomed Res Int 2019 21;2019:8498603. Epub 2019 Mar 21.

Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China.

Objective: The aim of this study is to evaluate the efficacy and safety of pulmonary rehabilitation (PR) in patients with idiopathic pulmonary fibrosis (IPF). s. Embase, PubMed, Cochrane Library, China National Knowledge Infrastructure (CNKI), Chongqing VIP (CQVIP), Wanfang Data, and Chinese Biomedical Literature Database (SinoMed) were comprehensively searched. Read More

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http://dx.doi.org/10.1155/2019/8498603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448340PMC
March 2019
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Integration of Traditional Birth Attendants into Mental Healthcare: A Multistakeholder Qualitative Study Exploration.

Biomed Res Int 2019 21;2019:8195267. Epub 2019 Mar 21.

Africa Mental Health Research and Training Foundation, Nairobi, Kenya.

Background: A significant number of people with common mental disorders are undiagnosed or undetected at primary healthcare facilities. The experience of traditional birth attendants (TBAs) in reassuring perinatal mothers could be utilized in maternal mental healthcare. The aim of this study was to gain insight into the feasibility of integrating TBAs into maternal mental healthcare using multiple stakeholder views. Read More

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http://dx.doi.org/10.1155/2019/8195267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448332PMC

The Immunomodulatory Effect of Alpha-Lipoic Acid in Autoimmune Diseases.

Biomed Res Int 2019 20;2019:8086257. Epub 2019 Mar 20.

Department of Rheumatology and immunology, Peking University International Hospital, Beijing 102206, China.

Αlpha-lipoic acid is a naturally occurring antioxidant in human body and has been widely used as an antioxidant clinically. Accumulating evidences suggested that -lipoic acid might have immunomodulatory effects on both adaptive and innate immune systems. This review focuses on the evidences and potential targets involved in the immunomodulatory effects of -lipoic acid. Read More

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http://dx.doi.org/10.1155/2019/8086257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446120PMC

Multimodal OCT Reflectivity Analysis of the Cystoid Spaces in Cystoid Macular Edema.

Biomed Res Int 2019 20;2019:7835372. Epub 2019 Mar 20.

Eye Clinic, University of Cagliari, Cagliari, Italy.

Purpose: To compare and evaluate images of macular cysts with different degrees of reflectivity (from gray to black signal) as observed in B scan spectral domain OCT (SDOCT) and EnFace OCT with decorrelation signal obtained with OCT-angiography (OCTA) in eyes with cystoid macular edema (CME) secondary to diabetic retinopathy (DR) and retinal vein occlusion (RVO).

Methods: Images from 3033 patients affected by CME secondary to diabetes or RVO examined OCTA (Optovue XR Avanti, Optovue, USA) at the University Eye Clinic of Créteil, Hôpital Intercommunal, France, and at the University Eye Clinic of Cagliari, "San Giovanni di Dio" Hospital, Italy, were retrospectively examined. The deep capillary plexus OCTA images and the corresponding EnFace OCT images, both acquired with the same automatic segmentation, had been overlapped to compose RGB color images as red and green channels, respectively, using ImageJ software (National Institutes of Health, Bethesda, MD). Read More

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http://dx.doi.org/10.1155/2019/7835372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446091PMC

Combined Optimized Effect of a Highly Self-Organized Nanosubstrate and an Electric Field on Osteoblast Bone Cells Activity.

Biomed Res Int 2019 21;2019:7574635. Epub 2019 Mar 21.

Department of Shoulder and Elbow Surgery, University Hospital of Patras, Rio, Greece.

The effect of an electric field within specific intensity limits on the activity of human cells has been previously investigated. However, there are a considerable number of factors that influence the in vitro development of cell populations. In biocompatibility studies, the nature of the substrate and its topography are decisive in osteoblasts bone cells development. Read More

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http://dx.doi.org/10.1155/2019/7574635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448337PMC

The Prevalence and Health Impacts of Frequent Work Discrimination and Harassment among Women Firefighters in the US Fire Service.

Biomed Res Int 2019 20;2019:6740207. Epub 2019 Mar 20.

Institute for Biobehavioral Health Research, National Development & Research Institutes, 1920 W. 143rd Street, Suite 120, Leawood, KS 66224, USA.

Intro: Both discrimination and harassment directly impact mental and physical health. Further, workplace discrimination degrades workplace culture and negatively impacts health behaviors, job-related outcomes, and family dynamics. Women represent a small proportion of the fire service and are often the targets of discrimination/harassment, yet little research documents the impact of such experiences. Read More

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https://www.hindawi.com/journals/bmri/2019/6740207/
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http://dx.doi.org/10.1155/2019/6740207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446094PMC
March 2019
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Effectiveness of Acupuncture Used for the Management of Postpartum Depression: A Systematic Review and Meta-Analysis.

Biomed Res Int 2019 20;2019:6597503. Epub 2019 Mar 20.

Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China.

Background: Previous studies have demonstrated that acupuncture was an effective alternative for treating major depressive disorders. However, the use of acupuncture for the treatment of postpartum depression remains controversial. This review summarizes the most significant studies in the area of acupuncture treatment for postpartum depression and provides a detailed overview of the efficacy of acupuncture for the treatment of postpartum depression. Read More

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http://dx.doi.org/10.1155/2019/6597503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446093PMC

Introducing of the First DCD Kidney Transplantation Program in Poland.

Biomed Res Int 2019 28;2019:6302153. Epub 2019 Feb 28.

Department of General and Transplant Surgery, Clinical Hospital of Poznan University of Medical Sciences, 60-355 Przybyszewski St. 49, Poland.

In many countries, including Poland, the main problem with transplantation is the insufficiency of organ donors in relation to the demand for organs. Hence, the common aim globally is to increase the pool of donors. The prolonged survival of patients after transplantation, with respect to the survival time of patients on dialysis, makes the search much more intense. Read More

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http://dx.doi.org/10.1155/2019/6302153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425340PMC
February 2019

Combined Effect of Secondhand Smoking and Alcohol Drinking on Risk of Persistent Human Papillomavirus Infection.

Biomed Res Int 2019 21;2019:5829676. Epub 2019 Mar 21.

Center for Cancer Prevention and Detection, Hospital, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si 10408, Republic of Korea.

Tobacco smoking is established as a cofactor of human papillomavirus (HPV) for cervical cancer risk. However, the role of secondhand smoking in cervical carcinogenesis is controversial. We aimed to assess the association between secondhand smoking and high risk- (HR-) HPV persistence, a pivotal event in development of cervical cancer. Read More

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http://dx.doi.org/10.1155/2019/5829676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448343PMC

Comparative Chloroplast Genomes of Species: Sequence Divergence and Phylogenetic Relationships.

Biomed Res Int 2019 19;2019:5046958. Epub 2019 Mar 19.

Institute of Plant Quarantine, Chinese Academy of Inspection and Quarantine, Beijing 100176, China.

Sorghum comprises 31 species that exhibit considerable morphological and ecological diversity. The phylogenetic relationships among S species still remain unresolved due to lower information on the traditional DNA markers, which provides a limited resolution for identifying species. In this study, we sequenced the complete chloroplast genomes of and and analyzed the published chloroplast genomes of and to retrieve valuable chloroplast molecular resources for . Read More

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https://www.hindawi.com/journals/bmri/2019/5046958/
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http://dx.doi.org/10.1155/2019/5046958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444266PMC
March 2019
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Syringobulbia in Patients with Chiari Malformation Type I: A Systematic Review.

Biomed Res Int 2019 19;2019:4829102. Epub 2019 Mar 19.

Department of Neurosurgery, First Affiliated Hospital, School of Medicine, Zhejiang University, China.

This study aimed to summarize the clinical features, diagnosis, and treatment of Chiari malformation type I- (CM-1-) associated syringobulbia. We performed a literature review of CM-1-associated syringobulbia in PubMed, Ovid MEDLINE, and Web of Science databases. Our concerns were the clinical features, radiologic presentations, treatment therapies, and prognoses of CM-1-associated syringobulbia. Read More

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http://dx.doi.org/10.1155/2019/4829102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444244PMC

Effects of Ticagrelor versus Clopidogrel in Patients with Coronary Bifurcation Lesions Undergoing Percutaneous Coronary Intervention.

Biomed Res Int 2019 20;2019:3170957. Epub 2019 Mar 20.

Department of Cardiology, Xinqiao Hospital, Army Medical University, Third Military Medical University, Chongqing 400037, China.

Background: Percutaneous treatment of coronary bifurcation lesions can potentially lead to higher risk of ischemic events than the nonbifurcation ones, thus calling for further optimization of dual antiplatelet therapy (DAPT). This study aimed to compare the clinical outcomes from ticagrelor and clopidogrel in bifurcation lesions patients undergoing percutaneous coronary intervention (PCI).

Methods: We performed a retrospective cohort study in patients with coronary bifurcation lesions. Read More

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https://www.hindawi.com/journals/bmri/2019/3170957/
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http://dx.doi.org/10.1155/2019/3170957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448338PMC
March 2019
1 Read

Pharmacokinetic Study of Delavinone in Mice after Intravenous and Oral Administration by UPLC-MS/MS.

Biomed Res Int 2019 21;2019:3163218. Epub 2019 Mar 21.

Analytical and Testing Centre, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.

Thirty-one compounds, including delavinone, were isolated from the methanol extract of by modern chromatographic techniques. The pharmacological action of is widely used in clinical practice. However, the pharmacokinetic studies on delavinone have not been reported. Read More

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http://dx.doi.org/10.1155/2019/3163218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448330PMC

NNS-Conjugated Chitosan Mediated IGF-1 and miR-140 Overexpression in Articular Chondrocytes Improves Cartilage Repair.

Biomed Res Int 2019 21;2019:2761241. Epub 2019 Mar 21.

Institute of Nanomedicine Technology, Department of Laboratory Medicine, Weifang Medical University, Weifang, Shandong 261053, China.

The aim of the present study was to investigate the effects of phosphorylatable nucleus localization signal linked nucleic kinase substrate short peptide (NNS)-conjugated chitosan (NNS-CS) mediated miR-140 and IGF-1 in both rabbit chondrocytes and cartilage defects model. NNS-CS was combined with pBudCE4.1-IGF-1, pBudCE4. Read More

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http://dx.doi.org/10.1155/2019/2761241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448336PMC

Relation between Red Cell Distribution Width and Mortality in Critically Ill Patients with Acute Respiratory Distress Syndrome.

Biomed Res Int 2019 21;2019:1942078. Epub 2019 Mar 21.

Department of Anesthesiology, Critical Care and Pain Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China.

Background: Currently, evidence regarding the predictive significance of red blood cell distribution width (RDW) among patients with acute respiratory distress syndrome (ARDS) remains scarce. The aim of this study was to determine the prognostic value of RDW for critically ill patients with ARDS.

Methods: We studied all patients with ARDS from the Multiparameter Intelligent Monitoring in Intensive Care Database III (MIMIC-III) for whom RDW was available. Read More

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http://dx.doi.org/10.1155/2019/1942078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448335PMC

Feature Selection for Longitudinal Data by Using Sign Averages to Summarize Gene Expression Values over Time.

Authors:
Suyan Tian Chi Wang

Biomed Res Int 2019 19;2019:1724898. Epub 2019 Mar 19.

Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, KY 40536, USA.

With the rapid evolution of high-throughput technologies, time series/longitudinal high-throughput experiments have become possible and affordable. However, the development of statistical methods dealing with gene expression profiles across time points has not kept up with the explosion of such data. The feature selection process is of critical importance for longitudinal microarray data. Read More

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http://dx.doi.org/10.1155/2019/1724898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444255PMC

An Inulin-Specific Lectin with Anti-HIV-1 Reverse Transcriptase, Antiproliferative, and Mitogenic Activities from the Edible Mushroom .

Biomed Res Int 2019 19;2019:1341370. Epub 2019 Mar 19.

State Key Laboratory for Agrobiotechnology and Department of Microbiology, China Agricultural University, Beijing 100193, China.

A novel lectin (ABL) was purified from the dried fruiting bodies of . An efficient 3-step purification protocol involved two consecutive steps of ion exchange chromatography on Q-Sepharose and SP-Sepharose and gel filtration by FPLC on Superdex 75. ABL is a monomeric protein with the molecular mass of 27. Read More

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http://dx.doi.org/10.1155/2019/1341370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444243PMC

Dynamic Expression Pattern of SERPINA1 Gene from Duck (Anas platyrhynchos).

Biomed Res Int 2019 19;2019:1321287. Epub 2019 Mar 19.

Key Laboratory of Animal Genetics & Breeding and Molecular Design of Jiangsu Province, Yangzhou University, Yangzhou, 225009, China.

SERPINA1 is a member of serine protease inhibitors and is increasingly considered to be a regulator of innate immunity in human and animals. However, the expression and function of SERPINA1 gene in immune defense against viral infection remain unknown in ducks. The full-length cDNA sequence was obtained using reverse transcription polymerase chain reaction (RT-PCR) and rapid amplification of cDNA ends (RACE). Read More

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http://dx.doi.org/10.1155/2019/1321287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444226PMC

Corrigendum to " Genome-Wide Analysis of the ATP-Binding Cassette Transporter Gene Family in Soybean ( L.) and Their Expression Profiling".

Biomed Res Int 2019 21;2019:1289174. Epub 2019 Mar 21.

Department of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk 38541, Republic of Korea.

[This corrects the article DOI: 10.1155/2019/8150523.]. Read More

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http://dx.doi.org/10.1155/2019/1289174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448327PMC

NHL Pathological Image Classification Based on Hierarchical Local Information and GoogLeNet-Based Representations.

Biomed Res Int 2019 21;2019:1065652. Epub 2019 Mar 21.

School of Science and Technology, Nottingham Trent University, Nottingham, UK.

Background: Accurate classification for different non-Hodgkin lymphomas (NHL) is one of the main challenges in clinical pathological diagnosis due to its intrinsic complexity. Therefore, this paper proposes an effective classification model for three types of NHL pathological images, including mantle cell lymphoma (MCL), follicular lymphoma (FL), and chronic lymphocytic leukemia (CLL).

Methods: There are three main parts with respect to our model. Read More

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http://dx.doi.org/10.1155/2019/1065652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448331PMC

The Dosimetric Comparisons of CRT, IMRT, ARC, CRT+IMRT, and CRT+ARC of Postoperative Radiotherapy in IIIA-N2 Stage Non-Small-Cell Lung Cancer Patients.

Biomed Res Int 2019 18;2019:8989241. Epub 2019 Mar 18.

Central South University of Xiangya Hospital, Department of Radiation Oncology, Changsha, Hunan 410008, China.

Currently, studies about PORT in stage IIIA-N2 NSCLC patients in recent years have mostly adopted the conformal radiation therapy (CRT) technique, while other modern techniques such as intensity modulated radiation therapy (IMRT), volumetric modulated arc therapy (VMAT, hereinafter referred to as ARC), helical tomotherapy (HT), and so forth are also developing quickly. In this paper, we intended to compare the dosimetric characteristics of CRT, IMRT, ARC, CRT+IMRT, and CRT+ARC of PORT in stage IIIA-N2 NSCLC patients. Ten patients with stage IIIA-N2 completely resected NSCLC, whom were treated by PORT in the radiotherapy department of our hospital from January 1, 2017, to January 1, 2018, were randomly selected in this study. Read More

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http://dx.doi.org/10.1155/2019/8989241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442440PMC
March 2019
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Stimulatory Effects of Boron Containing Bioactive Glass on Osteogenesis and Angiogenesis of Polycaprolactone: In Vitro Study.

Biomed Res Int 2019 18;2019:8961409. Epub 2019 Mar 18.

Department of Oral Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, China.

Polycaprolactone (PCL) has attracted great attention for bone regeneration attributed to its cost-efficiency, high toughness, and good processability. However, the relatively low elastic modulus, hydrophobic nature, and insufficient bioactivity of pure PCL limited its wider application for bone regeneration. In the present study, the effects of the addition of boron containing bioactive glass (B-BG) materials on the mechanical properties and biological performance of PCL polymer were investigated with different B-BG contents (0, 10, 20, 30, and 40 wt. Read More

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http://dx.doi.org/10.1155/2019/8961409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442456PMC

Prediction of Endometrial Hyperplasia and Cancer among Premenopausal Women with Abnormal Uterine Bleeding.

Biomed Res Int 2019 18;2019:8598152. Epub 2019 Mar 18.

Mother-Infant Department, Institute of Obstetrics and Gynecology, University of Modena and Reggio Emilia, Modena, Italy.

Objective: To create a prediction model including clinical variables for the prediction of premalignant/malignant endometrial pathology in premenopausal women with abnormal uterine bleeding (AUB).

Methods: This is an observational retrospective study including 240 premenopausal women with AUB referred to diagnostic hysteroscopy. Based on the presence of endometrial hyperplasia (EH) or cancer (EC), the women were divided into cases (EH/EC) and controls (no EH/EC). Read More

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https://www.hindawi.com/journals/bmri/2019/8598152/
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http://dx.doi.org/10.1155/2019/8598152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442314PMC
March 2019
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Medication-Related Osteonecrosis of the Jaws: Two Center Retrospective Cohort Studies.

Biomed Res Int 2019 18;2019:8345309. Epub 2019 Mar 18.

Clinic for Maxillofacial Surgery, School of Dental Medicine, University of Belgrade, Serbia.

This retrospective cohort study aims to describe characteristics of patients with MRONJ, to identify factors associated with MRONJ development, and to examine variables associated with favourable outcome. Totally 32 patients were followed and observed: 21 females and 11 males, in the age range 35-84 in the period from 2009 to 2018. Clinical, radiological examination (Orthopantomograph and CBCT) and biopsy were performed in order to achieve diagnosis. Read More

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https://www.hindawi.com/journals/bmri/2019/8345309/
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http://dx.doi.org/10.1155/2019/8345309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442486PMC
March 2019
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Vitamin D Receptor Gene Polymorphism: An Important Predictor of Arthritis Development.

Biomed Res Int 2019 18;2019:8326246. Epub 2019 Mar 18.

Cell and Molecular Biology Lab, Department of Zoology, University of the Punjab, Quaid-i-Azam Campus, Lahore 54590, Pakistan.

Vitamin D is an anti-inflammatory molecule and has a role in prevention of arthritis development. Biologically active form 1, 25(OH)D3 of vitamin D can only exert its action after binding its definite vitamin D receptor encoded by VDR gene. VDR gene polymorphism leads to dysfunctioning of 1, 25(OH)D ultimately disease onset. Read More

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https://www.hindawi.com/journals/bmri/2019/8326246/
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http://dx.doi.org/10.1155/2019/8326246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442488PMC
March 2019
1 Read

Self-Assembled Nanoscaled Metalloporphyrin for Optical Detection of Dimethylmethylphosphonate.

Biomed Res Int 2019 18;2019:7689183. Epub 2019 Mar 18.

Department of Biomedical Sciences, Chengdu Medical College, Chengdu, Sichuan 610500, China.

The self-assembly approach has been widely adopted in the effort to design and prepare functional materials. Herein, we report the synthesis and optical properties of metalloporphyrin nanoparticles. Nanoscaled particles of 5,10,15,20-tetraphenylporphyrin manganese (MnTPP) and 5,10,15,20-tetraphenylporphyrin indium (InTPP) were produced in the water/dimethylsulfoxide (DMSO) mixed solution by self-assembly approach. Read More

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http://dx.doi.org/10.1155/2019/7689183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442447PMC

Diabetes: Oral Health Related Quality of Life and Oral Alterations.

Biomed Res Int 2019 18;2019:5907195. Epub 2019 Mar 18.

Department of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, ME, Italy.

Background And Objectives: About 5% of the world's population is affected by diabetes; these patients must be further treated during medical and surgical treatments. These patients, due to the glycemic conditions, realize during their life multiorgan changes, in different body districts. Moreover, this condition obliges them to undertake hypoglycemic therapies. Read More

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http://dx.doi.org/10.1155/2019/5907195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442307PMC

Effects of Home-Based Robotic Therapy Involving the Single-Joint Hybrid Assistive Limb Robotic Suit in the Chronic Phase of Stroke: A Pilot Study.

Biomed Res Int 2019 18;2019:5462694. Epub 2019 Mar 18.

Graduate School of Sports and Health Sciences, Fukuoka University, Fukuoka, Japan.

Introduction: Robotic therapy has drawn attention in the rehabilitation field including home-based rehabilitation. A previous study has reported that home-based therapy could be more effective for increasing upper limb activity than facility-based therapy. The single-joint hybrid assistive limb (HAL-SJ) is an exoskeleton robot developed according to the interactive biofeedback theory, and several studies have shown its effectiveness for upper limb function in stroke patients. Read More

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http://dx.doi.org/10.1155/2019/5462694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442446PMC

Traumatic Atlantoaxial and Fracture-Related Dislocation.

Biomed Res Int 2019 18;2019:5297950. Epub 2019 Mar 18.

Department of Orthopaedics, Spine and Trauma Surgery, Helios Klinikum Siegburg, Siegburg, Germany.

Traumatic atlantoaxial dislocation due to ligamentous and combined osseous injuries rarely occurs in adults. There are only few cases published in the literature. In this level 4 study, a cohort of nine consecutive patients suffering from traumatic atlantoaxial dislocation has been analyzed regarding morphology of injury, trauma mechanism, and outcome since 2007. Read More

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http://dx.doi.org/10.1155/2019/5297950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442449PMC

Aberrant Interhemispheric Functional Organization in Children with Dyskinetic Cerebral Palsy.

Biomed Res Int 2019 18;2019:4362539. Epub 2019 Mar 18.

The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China, Chengdu 610054, China.

Background: Hemispheric asymmetry is one fundamental principle of neuronal organization. Interhemispheric connectivity and lateralization of intrinsic networks in the resting-state brain demonstrate the interhemispheric functional organization and can be affected by disease processes. This study aims to investigate the interhemispheric organization in children with dyskinetic cerebral palsy (DCP) based on resting-state functional MRI (fMRI). Read More

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http://dx.doi.org/10.1155/2019/4362539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442313PMC

Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB).

Biomed Res Int 2019 18;2019:3235021. Epub 2019 Mar 18.

Department of Breast and Thyroid Surgery, Zhongnan Hospital, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Wuhan University, Wuhan 430071, Hubei, China.

Background: Breast cancer (BC) is one of the most common malignant tumors in women around the world. Atorvastatin (ATO) was found to be associated with a decreased risk of recurrence and mortality in cancer. But the exact mechanism of its carcinostatic effects is unclear. Read More

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http://dx.doi.org/10.1155/2019/3235021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442491PMC

Oral Applications of Cyanoacrylate Adhesives: A Literature Review.

Biomed Res Int 2019 17;2019:8217602. Epub 2019 Mar 17.

Research Centre in Dental Sciences (CICO), Dental School, Universidad de La Frontera, Temuco, Chile.

Cyanoacrylate adhesives have been used in medicine and dentistry with some controversial opinions. The aim of this review was to summarize the relevant literature regarding the use of cyanoacrylate adhesives for oral wounds during dental and surgical procedures, with focus on the applications, indications, advantages, and disadvantages. In conclusion, and clinical studies have demonstrated in the last few years convincing results regarding the safety, efficacy, ease of application, and feasibility of all types of cyanoacrylate adhesives used in intra- and extraoral procedures. Read More

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http://dx.doi.org/10.1155/2019/8217602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441539PMC

Relationship of Natriuretic Peptides with Left Atrial Structure and Function within 1 Month after Electrical Cardioversion in Patients with Persistent Atrial Fibrillation.

Biomed Res Int 2019 17;2019:7636195. Epub 2019 Mar 17.

Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas LT-50161, Lithuania.

Atrial fibrillation (AF) despite the absence of heart failure is related to increased levels of natriuretic peptides (NPs). NPs have not been widely investigated in relation to left atrium (LA) function after sinus rhythm (SR) restoration and duration of AF. The aim of the study was to determine the changes of NPs levels and to define their relation with LA phasic function after electrical cardioversion (ECV). Read More

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http://dx.doi.org/10.1155/2019/7636195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441525PMC

Effectiveness of Platelet-Rich Fibrin as an Adjunctive Material to Bone Graft in Maxillary Sinus Augmentation: A Meta-Analysis of Randomized Controlled Trails.

Biomed Res Int 2019 17;2019:7267062. Epub 2019 Mar 17.

Department of Oral Implantology, Affiliated Stomatological Hospital of Fujian Medical University, Fuzhou, China.

Purpose: To date, it remains unknown whether the addition of platelet-rich fibrin (PRF) to bone grafts actually improves the effectiveness of maxillary sinus augmentation. This study aimed to perform a meta-analysis to evaluate the efficacy of PRF in sinus lift.

Materials And Methods: PubMed, Embase, and the Cochrane Library were searched. Read More

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http://dx.doi.org/10.1155/2019/7267062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441530PMC

First Description of Macrolide-Resistant in Adults with Community-Acquired Pneumonia in Italy.

Biomed Res Int 2019 17;2019:7168949. Epub 2019 Mar 17.

Department of Biomedical Sciences and Human Oncology-Hygiene Section, University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.

Background: is a common cause of community-acquired pneumonia (CAP). This cross-sectional study aimed to determine the prevalence of macrolide-resistant strains in a convenience series of 234 adult hospitalised and nonhospitalised subjects with a diagnosis of CAP in January 2013 to April 2015 in South Italy.

Methods: Respiratory samples were subjected to real-time PCR. Read More

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http://dx.doi.org/10.1155/2019/7168949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441498PMC

Cross-platform Data Analysis Reveals a Generic Gene Expression Signature for Microsatellite Instability in Colorectal Cancer.

Biomed Res Int 2019 17;2019:6763596. Epub 2019 Mar 17.

Faculty of Science, Research Centre for Toxic Compounds in the Environment, Masarykova Univerzita, Kamenice 5, Brno 625 00, Czech Republic.

The dysfunction of the DNA mismatch repair system results in microsatellite instability (MSI). MSI plays a central role in the development of multiple human cancers. In colon cancer, despite being associated with resistance to 5-fluorouracil treatment, MSI is a favourable prognostic marker. Read More

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http://dx.doi.org/10.1155/2019/6763596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441508PMC
March 2019
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Loratadine, an H Antihistamine, Inhibits Melanogenesis in Human Melanocytes.

Biomed Res Int 2019 17;2019:5971546. Epub 2019 Mar 17.

Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea.

It has long been believed that histamine is associated with cutaneous melanogenesis. Specifically, H2-receptor antagonists reportedly inhibit melanogenesis, but H1-receptor antagonists, which are some of the most commonly prescribed medicines in dermatology, have not been studied to determine whether and how they regulate melanogenesis. Therefore, we screened H1-receptor antagonists to determine whether they inhibit melanogenesis and found that loratadine was particularly effective, in this regard without compromising cellular viability. Read More

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http://dx.doi.org/10.1155/2019/5971546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441540PMC

Candy Closure Technique for Chronic Open Infective Lateral Malleolus Bursitis.

Biomed Res Int 2019 17;2019:5490139. Epub 2019 Mar 17.

Department of Foot and Ankle Surgery, Eulji Medical Center, Eulji University, 68 Hangeulbiseok-ro, Nowoungu, 01830 Seoul, Republic of Korea.

The aim of this study was to report the effectiveness of the Candy closure technique as a treatment for chronic open infective lateral malleolus bursitis. From June 2014 to March 2018, we performed the Candy closure technique as a treatment for chronic open infective lateral malleolus bursitis in nine patients without secondary operation. We first performed infectious tissue debridement to control infection, and if primary closure was not possible, we performed the Candy closure technique for small wounds. Read More

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https://www.hindawi.com/journals/bmri/2019/5490139/
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http://dx.doi.org/10.1155/2019/5490139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441521PMC
March 2019
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Comparison of Pharyngeal Airway between Mandibular Setback Surgery Patients (Skeletal Class III) and Nonsurgery Patients (Skeletal Classes I and II).

Biomed Res Int 2019 17;2019:5012037. Epub 2019 Mar 17.

Graduate Institute of Dental Sciences, School of Dental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

Purpose: We investigated the pharyngeal airway dimensions and their correlations in patients who underwent mandibular setback surgery versus those who did not.

Materials And Methods: One hundred and sixty cephalometric radiographs (120 patients) were obtained from patients with three skeletal malocclusion classifications: Class I and Class II in the nonsurgery group and Class III in the surgery group (preoperative and postoperative cephalograms). The following dimensions were measured: nasopharyngeal airway (NOP), uvulopharyngeal airway (UOP), shortest distance from the posterior tongue to the pharyngeal wall (TOP), and distance from the epiglottis to the pharyngeal wall (EOP). Read More

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http://dx.doi.org/10.1155/2019/5012037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441503PMC

Evaluation of Different Stabilizers and Inactivating Compounds for the Enhancement of Vero Cell Rabies Vaccine Stability and Immunogenicity: Study.

Biomed Res Int 2019 17;2019:4518163. Epub 2019 Mar 17.

Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Saudi Arabia.

Inactivation of rabies virus is essential for rabies vaccine preparation where the inactivating compound that is currently recommended for rabies vaccine preparation is -propiolactone (-PL). This compound is considered better than phenol and formalin but it is expensive and potentially carcinogenic. Data revealed that Ascorbic acid (AA) with cupric ions could yield complete and irreversible inactivation of rabies virus without adversely affecting its antigenicity. Read More

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http://dx.doi.org/10.1155/2019/4518163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441502PMC

Do Statins Have a Positive Impact on Patients with Coronary Microvascular Dysfunction on Long-Term Clinical Outcome? A Large Retrospective Cohort Study.

Biomed Res Int 2019 17;2019:4069097. Epub 2019 Mar 17.

Department of Cardiology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.

Objectives: To investigate the influence of statins on major adverse cardiovascular events (MACE) in patients with coronary microvascular dysfunction (CMVD).

Participants: 23,494 patients who received coronary angiography (CAG) were included. Thrombolysis in Myocardial Infarction, Myocardial Perfusion Grading (TMPG), a useful angiographic method, was used to evaluate CMVD. Read More

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http://dx.doi.org/10.1155/2019/4069097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441523PMC

Intestinal Perforation in ACTH-Dependent Cushing's Syndrome.

Biomed Res Int 2019 13;2019:9721781. Epub 2019 Mar 13.

Division of Endocrinology and Metabolism, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada T6G 2S2.

Previous studies have linked systemic glucocorticoid use with intestinal perforation. However, the association between intestinal perforation and endogenous hypercortisolism has not been well described, with only 14 previously published case reports. In this study, we investigated if intestinal perforation occurred more frequently in patients with ectopic ACTH syndrome and in those with a greater than 10-fold elevation of 24-hour urinary free cortisol level. Read More

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http://dx.doi.org/10.1155/2019/9721781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436364PMC

Mutant Lines of Spring Wheat with Increased Iron, Zinc, and Micronutrients in Grains and Enhanced Bioavailability for Human Health.

Biomed Res Int 2019 14;2019:9692053. Epub 2019 Mar 14.

Department of Biotechnology, Kazakh National University, Named After Al-Farabi, Almaty, Kazakhstan.

Deficiency of metals, primarily Fe and Zn, affects over half of the world's population. Human diets dominated by cereal products cause micronutrient malnutrition, which is common in many developing countries where populations depend heavily on staple grain crops such as wheat, maize, and rice. Biofortification is one of the most effective approaches to alleviate malnutrition. Read More

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http://dx.doi.org/10.1155/2019/9692053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437721PMC

Gastric Mucosal Lesions in Tibetans with High-Altitude Polycythemia Show Increased HIF-1A Expression and ROS Production.

Authors:
Kang Li Chaohui He

Biomed Res Int 2019 14;2019:6317015. Epub 2019 Mar 14.

The Fifth Affiliated Hospital of Zunyi Medical University, Zhuhai 519100, China.

Background: Living at a high plateau in a very hostile environment and low oxygen levels often leads to the development of high-altitude polycythemia (HAPC) and gastric mucosal lesions caused by high-level reactive oxygen species (ROS). Hypoxia-inducible factor-1A (HIF-1A) helps maintain oxygen homeostasis by promoting the transcription of various genes and can be affected by ROS levels. To evaluate the molecular mechanism by which HAPC causes the gastric mucosal lesions, the expression of HIF-1A was measured in Tibetans with HAPC and in healthy subjects. Read More

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https://www.hindawi.com/journals/bmri/2019/6317015/
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http://dx.doi.org/10.1155/2019/6317015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437737PMC
March 2019
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A Systematic Review of Right Ventricular Diastolic Assessment by 4D Flow CMR.

Biomed Res Int 2019 14;2019:6074984. Epub 2019 Mar 14.

Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, UK.

Background: Four-dimensional flow cardiovascular magnetic resonance (4D flow CMR) is a noninvasive novel imaging technology that can be used to visualise and assess right ventricular function. The aim of this systematic review is to summarise the literature available on 4D flow CMR methods used to determine right ventricular diastolic function.

Methods: A systematic review of current literature was carried out to ascertain what is known about right ventricular assessment by quantification of 4D flow CMR. Read More

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https://www.hindawi.com/journals/bmri/2019/6074984/
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http://dx.doi.org/10.1155/2019/6074984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437735PMC
March 2019
1 Read