Proenkephalin and risk of developing chronic kidney disease: the Prevention of Renal and Vascular End-stage Disease study.
- Lyanne M Kieneker,
- Oliver Hartmann,
- Andreas Bergmann,
- Rudolf A de Boer,
- Ron T Gansevoort,
- Michel M Joosten,
- Joachim Struck,
- Stephan J L Bakker
Biomarkers 2018 Feb 22:1-30. Epub 2018 Feb 22.
a University of Groningen, University Medical Center Groningen, Department of Internal Medicine , Groningen , the Netherlands.
Background: Proenkephalin (pro-ENK) was recently found to be associated with low eGFR. The association of pro-ENK with urinary albumin excretion (UAE), another marker for CKD, has not been investigated. We examined the association of pro-ENK with eGFR and UAE as a markers of CKD. Read More