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    6229 results match your criteria Biological trace element research[Journal]

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    Zinc Status in Beta Thalassemia Major Patients.
    Biol Trace Elem Res 2017 Sep 23. Epub 2017 Sep 23.
    Department of Pediatrics, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
    Beta thalassemia is a common monogenic hereditary hemoglobinopathy which is associated with compound complications. Zinc deficiency, which is commonly observed in thalassemia patients, is also associated with multiple health complications. The objective of this study was to determine the zinc status and its effect on the growth and immune functions of young beta thalassemia major patients. Read More

    Cytoprotective Effects of the Red Marine Alga Chondrus canaliculatus Against Maneb-Induced Hematotoxicity and Bone Oxidative Damages in Adult Rats.
    Biol Trace Elem Res 2017 Sep 22. Epub 2017 Sep 22.
    Unit of Functional Genomics and Plant Physiology, Higher Institute of Biotechnology of Sfax, University of Sfax, 3000, Sfax, Tunisia.
    The current study aimed at evaluating the ability of a mineral and antioxidant-rich extract from Chondrus canaliculatus to improve maneb (MB)-induced toxicity in adult rat. The animals were divided into four groups: group 1 used as a control group, group 2 received MB, group 3 received MB + C. canaliculatus extract, and group 4 received only the algal extract. Read More

    Trace Metal Levels in Rainbow Trout (Oncorhynchus mykiss) Cultured in Net Cages in a Reservoir and Evaluation of Human Health Risks from Consumption.
    Biol Trace Elem Res 2017 Sep 19. Epub 2017 Sep 19.
    Aquaculture Research Institute, Elazığ, Turkey.
    Although fish consumption has positive health effects, metals accumulated in fish can cause human health risks. In this study, the levels of ten metals in rainbow trout (Oncorhynchus mykiss) farmed in the Keban Dam Reservoir, which has the biggest rainbow trout production capacity in Turkey, were determined and compared with the maximum permissible levels (MPLs). Also, human health risks associated with rainbow trout consumption were assessed. Read More

    Nutrients Other than Selenium Are Important for Promoting Children's Health in Kashin-Beck Disease Areas.
    Biol Trace Elem Res 2017 Sep 18. Epub 2017 Sep 18.
    School of Public Health, Health Science Center, Xi'an Jiaotong University, Key Laboratory of Trace Elements and Endemic Diseases, National Health and Family Planning Commission, No.76 Yanta West Road, Xi'an, 710061, People's Republic of China.
    Overall nutritional status has been proved associated with people's health. The overall nutritional status of children in Kashin-Beck disease (KBD) areas has been overlooked for decades. Therefore, it is worth investigating in the current generation to gather evidence and make suggestions for improvement. Read More

    Manganese-Induced Neurotoxicity and Alterations in Gene Expression in Human Neuroblastoma SH-SY5Y Cells.
    Biol Trace Elem Res 2017 Sep 15. Epub 2017 Sep 15.
    Environmental Impact and Sustainability Division, CSIR-National Environmental Engineering Research Institute (NEERI), Nagpur, India.
    Manganese (Mn) is an essential trace element required for many physiological functions including proper biochemical and cellular functioning of the central nervous system (CNS). However, exposure to excess level of Mn through occupational settings or from environmental sources has been associated with neurotoxicity. The cellular and molecular mechanism of Mn-induced neurotoxicity remains unclear. Read More

    A Spectroscopic Study of Interaction of Auricyanide with n-Acetylcysteine.
    Biol Trace Elem Res 2017 Sep 14. Epub 2017 Sep 14.
    Department of Chemistry, Illinois State University, Normal, IL, 61790-4160, USA.
    Interaction of auricyanide, an important metabolite of anti-arthritic gold-based drug auranofin, was studied in vitro with a pharmacologically active ligand n-acetylcysteine with a view to understand reactivity of gold in vivo. Formation of reduction product aurocyanide occurred through mono- and di-n-acetylcysteine-substituted intermediates. The product and intermediates were identified and monitored spectrophotometrically and by electrospray ionization mass spectrometry. Read More

    Effects of Fluoride and/or Sulfur Dioxide on Morphology and DNA Integrity in Rats' Hepatic Tissue.
    Biol Trace Elem Res 2017 Sep 14. Epub 2017 Sep 14.
    Shanxi Key Laboratory of Environmental Veterinary Medicine, College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, 030801, China.
    This study was aimed to evaluate the toxic effects of fluoride (F) and/or sulfur dioxide (SO2) on morphology and DNA integrity in liver of male rats. For this, 96 Wistar rats (12-week-old) were randomly divided into four groups after 1-week adaptive breeding: the control group, treated with deionized water; the NaF group, administered high F (100 mg NaF/L in the drinking water); the SO2 group, with sulfur dioxide in ambient air (15 ppm SO2, 4 h/day); and NaF + SO2 group, treated with high F and sulfur dioxide together for 8 consecutive weeks. The body weight, liver organ coefficient, morphology, and DNA damage in the liver of rats were examined. Read More

    Preliminary Studies of Acute Cadmium Administration Effects on the Calcium-Activated Potassium (SKCa and BKCa) Channels and Na(+)/K(+)-ATPase Activity in Isolated Aortic Rings of Rats.
    Biol Trace Elem Res 2017 Sep 13. Epub 2017 Sep 13.
    Federal University of Espírito Santo, Graduate Program in Physiological Sciences, Vitória, ES, Brazil.
    Cadmium is an environmental pollutant closely linked with cardiovascular diseases that seems to involve endothelium dysfunction and reduced nitric oxide (NO) bioavailability. Knowing that NO causes dilatation through the activation of potassium channels and Na(+)/K(+)-ATPase, we aimed to determine whether acute cadmium administration (10 μM) alters the participation of K(+) channels, voltage-activated calcium channel, and Na(+)/K(+)-ATPase activity in vascular function of isolated aortic rings of rats. Cadmium did not modify the acetylcholine-induced relaxation. Read More

    Effect of Zinc Supplementation on Growth Performance, Intestinal Development, and Intestinal Barrier-Related Gene Expression in Pekin Ducks.
    Biol Trace Elem Res 2017 Sep 11. Epub 2017 Sep 11.
    Animal Nutrition Institute, Sichuan Agricultural University, No. 211 Huimin Road, Wenjiang, Chengdu, Sichuan, 611130, China.
    The current study was conducted to investigate the effect of zinc supplementation on the growth performance, intestinal morphology, and the transcription of the barrier function related genes in Pekin ducks. Seven-hundred and sixty-eight 1-day-old Pekin ducks were randomly assigned into six dietary treatments. Each treatment had eight replicates with 16 ducks per replicates. Read More

    How Bad Is Aluminum Exposure to Reproductive Parameters in Rats?
    Biol Trace Elem Res 2017 Sep 8. Epub 2017 Sep 8.
    Department of General Biology, Federal University of Viçosa (UFV), Av. P.H. Rolfs, s/n, Campus Universitário, Viçosa, Minas Gerais, Brazil.
    Aluminum (Al) is the most widely distributed metal in the environment and is extensively used in human daily life without any known biological function. It is known that exposure to high concentrations of Al impacts negatively on serum testosterone levels, testicular histomorphometry, and sperm parameters; however, no information is available about the effects of low exposure levels on reproduction. International organizations have established the Al concentration tolerated in drinking water as 3. Read More

    The Study on the Correlation Between Six Kinds of Mineral Elements and Diabetes.
    Biol Trace Elem Res 2017 Sep 7. Epub 2017 Sep 7.
    Department of Epidemiology and Biostatistics, Jilin University School of Public Health, Changchun, China.
    The study aimed to explore the relationship of six kinds of mineral elements and diabetes among adults in northeast China. A cross-sectional survey was conducted in Jilin Province, northeast China. A total of 366 males and 204 females aged 18 ~ 77 years from Jingyu town, Dongliao town, and Changling town were included using a multistage stratified random cluster sampling design. Read More

    [Cr3O(O2CCH2CH3)6(H2O)3]NO3·H2O (Cr3) Toxicity Potential in Bacterial and Mammalian Cells.
    Biol Trace Elem Res 2017 Sep 7. Epub 2017 Sep 7.
    Department of Biological Sciences, Emporia State University, Emporia, KS, USA.
    Chromium(III) has generally been considered to be essential for proper carbohydrate and lipid metabolism, and, despite recent evidence to the contrary, chromium(III)-containing compounds remain one of the most popular commercial dietary supplements. Cr3, or [Cr3O(O2CCH2CH3)6(H2O)3]NO3·H2O, is a trivalent chromium compound that is a promising chromium nutritional supplement. Studies with Cr3 have indicated that it is non-toxic in developmental and short- and long-term exposure studies in rodents, but the safety of this compound to chromosomes and cells has not been explored. Read More

    Effects of Arsenic Compounds on Microminerals Content and Antioxidant Enzyme Activities in Rat Liver.
    Biol Trace Elem Res 2017 Sep 6. Epub 2017 Sep 6.
    Department of General Biology, Federal University of Viçosa, Av. P.H. Rolfs, s/n, Campus Universitário, Viçosa, Minas Gerais, 36570-900, Brazil.
    Interactions of arsenic with essential trace elements may result in disturbances on body homeostasis. In the present study, we aimed to investigate the effects of different arsenic compounds on micromineral content and antioxidant enzyme activities in rat liver. Male Wistar rats were randomly divided into five groups and exposed to sodium arsenite and sodium arsenate at 0. Read More

    The Effects of Selenium Supplementation on Gene Expression Related to Insulin and Lipid in Infertile Polycystic Ovary Syndrome Women Candidate for In Vitro Fertilization: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Biol Trace Elem Res 2017 Sep 5. Epub 2017 Sep 5.
    Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran.
    This study was conducted to evaluate the effects of selenium supplementation on gene expression related to insulin and lipid in infertile women with polycystic ovary syndrome (PCOS) candidate for in vitro fertilization (IVF). This randomized double-blind, placebo-controlled trial was conducted among 40 infertile women with PCOS candidate for IVF. Subjects were randomly allocated into two groups to intake either 200-μg selenium (n = 20) or placebo (n = 20) per day for 8 weeks. Read More

    Inflammatory Response Occurs in Veins of Broiler Chickens Treated with a Selenium Deficiency Diet.
    Biol Trace Elem Res 2017 Sep 4. Epub 2017 Sep 4.
    Department of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
    Selenium (Se) has been indicated to prevent chronic diseases including cancer, cardiovascular disease, and type 2 diabetes. However, a few studies have indicated that Se deficiency can induce vascular diseases. Thus, in the present study, we investigated the effect of Se deficiency on vascular pathology. Read More

    Protective Effects of Dietary Garlic Powder Against Cadmium-induced Toxicity in Sea Bass Liver: a Chemical, Biochemical, and Transcriptomic Approach.
    Biol Trace Elem Res 2017 Sep 2. Epub 2017 Sep 2.
    Laboratoire de Biochimie et Toxicologie Environnementale, ISA, Chott-Mariem, 4042, Sousse, Tunisia.
    To investigate the protective effect of garlic powder on cadmium-induced toxicity sea bass liver, juvenile fishes where maintained under three food diets (diet 1: normal without garlic supply, diet 2: 2% garlic powder; diet 3: 6% garlic powder). After 30 days of specific diets, each group was injected with 500 μg kg(-1)of Cd. The control group was the one fed with normal diet and not injected with Cd. Read More

    Copper, Manganese, Zinc, and Cadmium in Tea Leaves of Different Types and Origin.
    Biol Trace Elem Res 2017 Sep 2. Epub 2017 Sep 2.
    Department of Food Chemistry and Nutrition, Medical College, Jagiellonian University, Medyczna 9 St., 30-688, Cracow, Poland.
    Concentrations of selected metals (Cu, Mn, Zn, Cd) in tea leaves were investigated. Samples included black, green, and other (red, white, yellow, and oolong) teas. They were purchased on a local market but they covered different countries of origin. Read More

    Comparison of the Trace Elements and Active Components of Lonicera japonica flos and Lonicera flos Using ICP-MS and HPLC-PDA.
    Biol Trace Elem Res 2017 Sep 1. Epub 2017 Sep 1.
    Liaoning University of Traditional Chinese Medicine, 77 Life One Road, DD port, Dalian Economic and Technical Development Zone, Dalian, 116600, People's Republic of China.
    Thirteen trace elements and active constituents of 40 batches of Lonicera japonica flos and Lonicera flos were comparatively studied using inductively coupled plasma mass-spectrometry (ICP-MS) and high-performance liquid chromatography-photodiode array (HPLC-PDA). The trace elements were (24)Mg, (52)Cr, (55)Mn, (57)Fe, (60)Ni, (63)Cu, (66)Zn, (75)As, (82)Se, (98)Mo, (114)Cd, (202)Hg, and (208)Pb, and the active compounds were chlorogenic acid, 3,5-O-dicaffeoylquinc acid, 4,5-O-dicaffeoylquinc acid, luteolin-7-O-glucoside, and 4-O-caffeoylquinic acid. The data of 18 variables were statistically processed using principal component analysis (PCA) and discriminate analysis (DA) to classify L. Read More

    Interaction of Lead with Calcium, Iron, and Zinc in the Biological Samples of Malnourished Children.
    Biol Trace Elem Res 2017 Aug 31. Epub 2017 Aug 31.
    National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, 76080, Pakistan.
    Interaction between toxic and essential elements is of particular interest, because the deficiency of essential element can dramatically increase the absorption rate of toxic metals inside the body. This study was conducted to evaluate the possible correlation of lead (Pb) with calcium (Ca), iron (Fe), and zinc (Zn) in biological samples (whole blood and scalp hair) of malnourished children (MNC). For comparative purposes, age-matched, well-nourished children (WNC) were selected. Read More

    Umbilical Serum Copper Status and Neonatal Birth Outcomes: a Prospective Cohort Study.
    Biol Trace Elem Res 2017 Aug 31. Epub 2017 Aug 31.
    Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
    Our study aimed to assess the distribution of copper (Cu) in umbilical cord serum and estimated the association between umbilical serum Cu status and neonatal birth outcomes in a Chinese population. Through the Ma'anShan Birth Cohort Study, 2689 maternal-singleton pairs with detailed birth records and available serum samples were identified. The tertile levels of ln-transformed Cu were used to define low, medium, and high levels for serum Cu. Read More

    Chromium Supplementation Reduces Resting Heart Rate in Patients with Metabolic Syndrome and Impaired Glucose Tolerance.
    Biol Trace Elem Res 2017 Aug 30. Epub 2017 Aug 30.
    Research Department, Pharma Nord ApS, Vejle, Denmark.
    Chromium (Cr) is considered as an important mineral, involved in biochemical reactions in human metabolic pathways. Organically bound Cr supplementation has been suggested to improve glycemia especially in patients with type 2 diabetes mellitus, but there are conflicting reports on efficacy. Effect of Cr is not clear in prediabetes status. Read More

    Size-Dependent Neurotoxicity of Aluminum Oxide Particles: a Comparison Between Nano- and Micrometer Size on the Basis of Mitochondrial Oxidative Damage.
    Biol Trace Elem Res 2017 Aug 30. Epub 2017 Aug 30.
    Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
    Aluminum nanoparticles (AlNPs) are among the most abundantly produced nanosized particles in the market. There is limited information about the potential harmful effects of aluminum oxide due to its particle size on human health. Considering the toxic effects of Al on brain as its target tissue, in this study, the toxicity of nanoparticles, microparticles, and ionic forms of Al on rat brain and isolated mitochondria was evaluated. Read More

    Aluminum Chloride Causes the Dysfunction of Testes Through Inhibiting the ATPase Enzyme Activities and Gonadotropin Receptor Expression in Rats.
    Biol Trace Elem Res 2017 Aug 30. Epub 2017 Aug 30.
    Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, Northeast Agricultural University, Harbin, 150030, China.
    The aim of this experiment is to explore the effects of aluminum chloride (AlCl3) on the ATPase enzymes and gonadotropin receptors in the testes. Eighty male Wistar rats were orally exposed to 0 mg/kg body weight (BW) (control group, CG), 64 mg/kg BW (low-dose group, LG), 128 mg/kg BW (mid-dose group, MG), or 256 mg/kg BW (high-dose group, HG) for 120 days. The microstructure and ultrastructure of testes; the activities of Na(+)-K(+)-ATPase, Mg(2+)-ATPase, and Ca(2+)-ATPase; and the mRNA and protein expressions of follicle-stimulating hormone receptor (FSHR) and luteinizing hormone receptors (LHR) in the testes were examined. Read More

    Hair Zinc: an Index for Zinc Status in Under-Five Children from Low-Income Communities in Kanam Area of North-Central Nigeria.
    Biol Trace Elem Res 2017 Aug 28. Epub 2017 Aug 28.
    Department of Nutritional Sciences, College of Human Sciences, Oklahoma State University, Stillwater, OK, 74078, USA.
    Nutritional deficiencies of trace elements are among the top ten causes of death in Sub Saharan Africa. In Kanam Local Government Area of Nigeria, the problem is compounded by high levels of poverty and illiteracy. Abnormally low hair zinc levels are important, sensitive diagnostic biochemical indices of Zinc deficiency. Read More

    Synergistic Effects of Genistein and Zinc on Bone Metabolism and the Femoral Metaphyseal Histomorphology in the Ovariectomized Rats.
    Biol Trace Elem Res 2017 Aug 25. Epub 2017 Aug 25.
    Vitamin D Research Institute, Shaanxi University of Technology, Chaoyang Road, Hantai District, Hanzhong City, Shaanxi Province, 723000, China.
    In this study, we evaluated the synergistic effects of genistein and zinc on bone metabolism, bone mineral density, and the femoral metaphyseal histomorphology in the ovariectomized rats. Sixty female Sprague-Dawley rats, aged 13 weeks, were divided into sham-operated group (SHAM), ovariectomized group (OVX), genistein-treated group (OVX-Gen), zinc-treated group (OVX-Zn), genistein combined zinc-treated group (OVX-Gen-Zn), and 17β-estradiol-treated group (OVX-E) (n = 10). Genistein, zinc, and 17β-estradiol injections were started immediately after OVX and continued for 10 weeks. Read More

    Gold and Female Reproductive Organs: an Ultrastructural Study.
    Biol Trace Elem Res 2017 Aug 24. Epub 2017 Aug 24.
    Laboratory of Physiology, Faculty of Medicine of Tunis, University of Tunis El Manar, 15 Rue Djebel Lakhdhar. La Rabta, 1007, Tunis, Tunisia.
    Gold, a heavy yellow-colored metal, is usually found in nature as a metallic element or as salts. This noble metal historically had a reputation as an anti-inflammatory medicine for rheumatoid arthritis, a nervine, and a remedy for nervous disorders, as well as a potential anticancer agent. It has also been used as component in dental restorations and in implant materials. Read More

    Organic Gallium Treatment Improves Osteoporotic Fracture Healing Through Affecting the OPG/RANKL Ratio and Expression of Serum Inflammatory Cytokines in Ovariectomized Rats.
    Biol Trace Elem Res 2017 Aug 24. Epub 2017 Aug 24.
    Department of Orthopedic Surgery, Shengjing Hospital of China Medical University, 36 Sanhao Street, Heping District, Shenyang, 110004, People's Republic of China.
    This study aimed to investigate the impact of organic gallium (OG) on osteoporotic fracture healing in ovariectomized female Sprague-Dawley rats, as well as study the mechanisms of OG on osteoporotic fracture healing. Forty-five female Sprague-Dawley rats were divided into three groups: sham operation group (Sxas control group), ovariectomized group (Ovx), and Ovx treated with OG group (Ovx + OG). Rat femoral fractures were studied using a standardized fracture-healing model utilizing bone fixation with an intramedullary pin. Read More

    Statistical Evaluation of Trace Metals, TSH and T4 in Blood Serum of Thyroid Disease Patients in Comparison with Controls.
    Biol Trace Elem Res 2017 Aug 23. Epub 2017 Aug 23.
    Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
    The present study is based on the measurement of concentrations of selected trace metals (Fe, Zn, Cu, Co, Mn, Ni, Cr, Cd and Pb) and thyroid hormones (TSH and T4) in blood serum of hypothyroid and hyperthyroid patients in comparison with healthy donors/controls in order to establish the imbalances of the trace metals in diseased subjects. The serum samples were digested in HNO3-HClO4 mixture and quantification of the metals was performed by flame atomic absorption spectrometry. Average levels of Fe, Ni, Cu, Cr, Pb and TSH were found to be significantly higher (p < 0. Read More

    Iron: a Strong Element in the Pathogenesis of Chronic Hyperglycaemia After Acute Pancreatitis.
    Biol Trace Elem Res 2017 Aug 23. Epub 2017 Aug 23.
    Department of Surgery, University of Auckland, Room 12.085A, Level 12, Auckland City Hospital, Private Bag 92019, Victoria Street West, Auckland, 1142, New Zealand.
    Evidence shows an association between markers of iron metabolism and glucose metabolism in type 2 diabetes mellitus. Acute pancreatitis is the largest contributor to diabetes of the exocrine pancreas. However, the pathogenesis of new-onset pre-diabetes or diabetes after pancreatitis remains unclear. Read More

    Selenoprotein N Was Required for the Regulation of Selenium on the Uterine Smooth Muscle Contraction in Mice.
    Biol Trace Elem Res 2017 Aug 23. Epub 2017 Aug 23.
    Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China.
    Selenium (Se) is an essential micronutrient affecting various aspects of health. The balance of the Se concentration has an important protective and promoter effect on physiological function in inducing muscular disorders in smooth muscle. Selenoprotein N (SelN) is closely related to Ca(2+) release. Read More

    Mercury Exposure: Protein Biomarkers of Mercury Exposure in Jaraqui Fish from the Amazon Region.
    Biol Trace Elem Res 2017 Aug 21. Epub 2017 Aug 21.
    Institute of Bioscience of Botucatu, São Paulo State University (UNESP), Rubião Júnior, Botucatu, São Paulo, 18618-970, Brazil.
    This study presents data on the extraction and characterization of proteins associated with mercury in the muscle and liver tissues of jaraqui (Semaprochilodus spp.) from the Madeira River in the Brazilian Amazon. Protein fractionation was carried out by two-dimensional electrophoresis (2D-PAGE). Read More

    Analysis and Risk Assessment of Seven Toxic Element Residues in Raw Bovine Milk in China.
    Biol Trace Elem Res 2017 Aug 19. Epub 2017 Aug 19.
    College of Animal Science and Technology, Shihezi University, No. 4, the North Road, Shihezi, Xinjiang, 832002, People's Republic of China.
    The object of this study is to analyze the levels of seven toxic elements residues in raw bovine milk in China and assess the potential health risk of those residues. The 178 raw bovine milk samples were collected from eight main milk-producing provinces and from three types of milk stations in China, and were analyzed for arsenic (As), lead (Pb), cadmium (Cd), chromium (Cr), mercury (Hg), aluminum (Al), and nickel (Ni) using inductively coupled plasma-mass spectrometry (ICP-MS). Al, Pb, Hg, Ni, Cr, and As were detected in 47. Read More

    The Inflammatory Potential of Dietary Manganese in a Cohort of Elderly Men.
    Biol Trace Elem Res 2017 Aug 18. Epub 2017 Aug 18.
    Center for Population Epigenetics, Robert H. Lurie Comprehensive Cancer Center and Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
    Manganese is an essential nutrient that may play a role in the production of inflammatory biomarkers. We examined associations between estimated dietary manganese intake from food/beverages and supplements with circulating biomarkers of inflammation. We further explored whether estimated dietary manganese intake affects DNA methylation of selected genes involved in the production of these biomarkers. Read More

    Network Analysis of Se-and Zn-related Proteins in the Serum Proteomics Expression Profile of the Endemic Dilated Cardiomyopathy Keshan Disease.
    Biol Trace Elem Res 2017 Aug 18. Epub 2017 Aug 18.
    School of Public Health, Health Science Center of Xi'an Jiaotong University, No. 76 Yanta West Road, Xi'an, Shaanxi, 710061, China.
    Keshan disease (KD) is an endemic cardiomyopathy with high mortality. Selenium (Se) and zinc (Zn) deficiencies are closely related to KD. The molecular mechanism of KD pathogenesis is still unclear. Read More

    sEcad and EGF Levels Increased in Urine of Non-ferrous Metal Workers and Medium of Uroepithelial Cell Line Treated by Arsenic.
    Biol Trace Elem Res 2017 Aug 17. Epub 2017 Aug 17.
    Department of Environmental and Occupational Health, Liaoning Provincial Key Laboratory of Arsenic Biological Effect and Poisoning, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang, 110122, Liaoning Province, People's Republic of China.
    Inorganic arsenic (iAs) is a carcinogen and could increase the risks of bladder, lung, and skin cancer. Mining and smelting of non-ferrous metals are common occupational arsenic exposures. In this study, 125 individuals working in non-ferrous metal smelting plants were separated into two groups according to urinary total arsenic (TAs) levels: group 1, TAs < 100 μg/g Cr; group 2, TAs ≥ 100 μg/g Cr. Read More

    Mitigation of Acute Aluminum Toxicity by Sodium Selenite and N-Acetylcysteine in Adult Male Rats.
    Biol Trace Elem Res 2017 Aug 17. Epub 2017 Aug 17.
    Faculty of Science, Department of Zoology, University of Ain Shams, Abbassia, Cairo, 11566, Egypt.
    The objective of this study is to investigate the toxic effects of aluminum and the potential alleviation of selenite and N-acetylcysteine (NAC) on this toxicity. Acute aluminum toxicity was induced by intraperitoneal (i.p. Read More

    Effects of Se and Cd Co-treatment on the Morphology, Oxidative Stress, and Ion Concentrations in the Ovaries of Laying Hens.
    Biol Trace Elem Res 2017 Aug 16. Epub 2017 Aug 16.
    College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
    This study aims at revealing the effects of the combined treatment of selenium and cadmium on ovary morphology, oxidative stress, and 28 kinds of ion concentrations in laying hens. In this experiment, 128 healthy 31-week-old chickens were selected and divided into four treatment groups, three of which were separately fed the basic diets supplemented with either Se or Cd or both Se and Cd for 90 days, and the remaining group was fed the basic diet and treated as a control. The chickens were sacrificed for collecting ovarian tissues. Read More

    Supplemented Organic and Inorganic Selenium Affects Milk Performance and Selenium Concentration in Milk and Tissues in the Guanzhong Dairy Goat.
    Biol Trace Elem Res 2017 Aug 16. Epub 2017 Aug 16.
    College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
    Trace amounts of selenium (Se) are essential for several organisms, and deficiencies therein have adverse effects on growth, development, and reproduction; this is particularly significant in animals raised for milk and livestock production. To study the effect of Se on Guanzhong dairy goats, their diets were supplemented with different sources (inorganic or organic) and Se concentrations (0.2 or 0. Read More

    Effect of Low-Selenium/High-Fat Diet on Pig Peripheral Blood Lymphocytes: Perspectives from Selenoproteins, Heat Shock Proteins, and Cytokines.
    Biol Trace Elem Res 2017 Aug 15. Epub 2017 Aug 15.
    College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
    The aim of the present study was to clarify the effect of low selenium (Se)/high fat on the mRNA expression of selenoproteins, heat shock proteins (HSPs) and cytokines in pig peripheral blood lymphocytes. Forty crossbred boar piglets with healthy lean body weights of 10 kg were randomly divided into four treatment groups (group C, group L-Se, group H-fat, and group L-Se-H-fat) (n = 10/group) and fed with the corresponding diet for 16 weeks. The pig peripheral blood lymphocytes were extracted, and the mRNA expression of selenoproteins, HSPs, and cytokines was measured. Read More

    Zinc Metabolism and Metallothioneins.
    Biol Trace Elem Res 2017 Aug 15. Epub 2017 Aug 15.
    Department of Physiology, Medical Faculty, Selcuk University, Konya, Turkey.
    Among the trace elements, zinc is one of the most used elements in biological systems. Zinc is found in the structure of more than 2700 enzymes, including hydrolases, transferases, oxyreductases, ligases, isomerases, and lyases. Not surprisingly, it is present in almost all body cells. Read More

    Association of Elements with Schizophrenia and Intervention of Selenium Supplements.
    Biol Trace Elem Res 2017 Aug 15. Epub 2017 Aug 15.
    Shandong University, Number 44 in Wenhua Road, Lixia Distrct, Jinan, China.
    The purpose of this study is to explore more trace elements (zinc, potassium, copper, iron, boron, manganese, selenium, chromium and cadmium elements) in addition to calcium, magnesium, lead and arsenic in the sera of patients with schizophrenia and the general population in China and to determine the effect of selenium on schizophrenia patients. Participants were collected from the Pingyin County Mental Health Hospital and Pingyin County. A t test was used to analyse the differences between schizophrenia patients and healthy subjects, and element content differences in gender. Read More

    Effects of Fluoride on Surface Structure of Primary Culture Leydig Cells in Mouse.
    Biol Trace Elem Res 2017 Aug 15. Epub 2017 Aug 15.
    Shanxi Key Laboratory of Ecological Animal Science and Environmental Veterinary Medicine, College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, 030801, China.
    Fluoride (F) is known to induce reproduction toxicity, and the elucidation of its underlying mechanisms is an ongoing research. These findings aim to provide deeper insights into roles of soduim fluoride (NaF) in testis damage, which could contribute to a better understanding of fluoride-induced male reproductive toxicity. The Leydig cells were administrated by 0, 5, 10, and 20 mg/L NaF for 24 h, respectively. Read More

    Speciation of As(ΙΙΙ)/As(V) and Total Inorganic Arsenic in Biological Fluids Using New Mode of Liquid-Phase Microextraction and Electrothermal Atomic Absorption Spectrometry.
    Biol Trace Elem Res 2017 Aug 12. Epub 2017 Aug 12.
    Research Center for Environmental Determinants of Health (RCEDH), Kermanshah University of Medical Sciences, Kermanshah, Iran.
    In this paper, a new extraction method based on countercurrent liquid-liquid microextraction (CLLME) has been developed for the extraction and preconcentration of inorganic arsenic (iAs) in plasma and urine samples prior to their analysis by electrothermal atomic absorption spectrometry (ETAAS). In this method, firstly, 5 ml of water is added to the extraction vessel. Then 30. Read More

    Iodine-Rich Herbs and Potassium Iodate Have Different Effects on the Oxidative Stress and Differentiation of TH17 Cells in Iodine-Deficient NOD.H-2(h4) Mice.
    Biol Trace Elem Res 2017 Aug 12. Epub 2017 Aug 12.
    The First Clinical College, Liaoning University of Traditional Chinese Medicine (TCM), Chongshan East Road No.72, Shenyang, Liaoning, 110032, China.
    Iodine-rich herbs such as seaweed, kelp, and sea tangle were widely used to treat various types of goiter with good effect and without any adverse side effects in China. When compared with potassium iodate (PI), iodine-rich herbs had a positive effect on the recovery of goiter resulting from iodine deficiency without any obvious harmful effects. In NOD. Read More

    Alleviation of Arsenic-Induced Pulmonary Oxidative Damage by GSPE as Shown during In vivo and In vitro Experiments.
    Biol Trace Elem Res 2017 Aug 12. Epub 2017 Aug 12.
    Shihezi University School of Medicine, Shihezi, Xinjiang, 832000, China.
    A long-term exposure to arsenic may lead to lung damage due to oxidative stress. In this context, GSPE can play a major role as a strong antioxidant. Our study attempted to reveal the connection between arsenic-induced lung injury and the antagonistic effect of GSPE. Read More

    Growth Performance, Mineral Digestibility, and Blood Characteristics of Ostriches Receiving Drinking Water Supplemented with Varying Levels of Chelated Trace Mineral Complex.
    Biol Trace Elem Res 2017 Aug 11. Epub 2017 Aug 11.
    Department of Research and Development, Sodour Ahrar Shargh Company, Tehran, Iran.
    The effects of water supplementation of chelated trace minerals (CTM, which is named Bonzaplex designed with chelate compounds technology) on growth performance, apparent total tract digestibility (ATTD) of minerals, and some blood metabolites, TM, and antioxidant enzyme values in African ostriches were investigated from 8 to 12 months of age. A total of 20 8-month-old ostriches (five birds in five replicate pens) was randomly allocated into one of the following four treatments: (1) control (basal diet + tap water), (2) low CTM (basal diet +100 mg/bird/day CTM powder in tap water), (3) medium CTM (basal diet +1 g/bird/day CTM powder in tap water), and (4) high CTM (basal diet +2 g/bird/day CTM powder in tap water). Compared with control, medium CTM improved (P < 0. Read More

    Effect of Disturbances of Zinc and Copper on the Physical and Mental Health Status of Patients with Alcohol Dependence.
    Biol Trace Elem Res 2017 Aug 12. Epub 2017 Aug 12.
    Department of Pharmacodynamics, Centre for Preclinical, Research and Technology (CePT), Medical University of Warsaw, Warsaw, Poland.
    The concentrations of copper and zinc in the tissues of alcohol-addicted people can significantly correlate with the variables describing their mental state. Studies on the homeostasis of zinc in alcohol-dependent patients have often been characterized by low hypozincemia detection. This may be caused by a low content of zinc in blood serum (1%) compared to the average zinc level in the body. Read More

    Trace Element and Heavy Metal Levels in Colorectal Cancer: Comparison Between Cancerous and Non-cancerous Tissues.
    Biol Trace Elem Res 2017 Aug 9. Epub 2017 Aug 9.
    Gastrointestinal and Liver Disease Research Center (GILDRC), Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
    Cases of colorectal cancer (CRC) have increased dramatically in Middle Eastern and other Asian countries. Many studies indicate an important role of environmental factors, including trace elements as an etiology of cancer. This study aims to assess the concentration of eight trace elements in cancerous and adjacent non-cancerous tissues in case of CRC. Read More

    Identification and Characterization of Cadmium-Related Genes in Liver Carcinoma.
    Biol Trace Elem Res 2017 Aug 8. Epub 2017 Aug 8.
    College of Food Science and Nutritional Engineering, China Agriculture University, Beijing, China.
    Evidence indicates that exposure to heavy trace element might be a risk factor for liver carcinoma. Cadmium has been supposed to be a carcinogen that has a correlation with the risk of a number of cancers, including liver cancer. However, the mechanisms underlying Cadmium-induced malignant transformation in liver cells are not fully understood. Read More

    Selenium Deficiency Augments the Levels of Inflammatory Factors and Heat Shock Proteins via the Redox Regulatory Pathway in the Skeletal Muscles of Mice.
    Biol Trace Elem Res 2017 Aug 5. Epub 2017 Aug 5.
    Department of Osteology, The Daqing Oilfield General Hospital, Daqing, 163319, Heilongjiang, People's Republic of China.
    Dietary selenium (Se) deficiency is known to cause myodynia syndrome and Se influences immune responses by changing the expression of inflammatory cytokines and heat shock proteins (Hsps), but the details are not completely elucidated. In the present study, 72 1-day-old mice were divided into two groups; the first group was fed a Se-sufficient diet, while the second group was fed a Se-deficient diet. Skeletal muscles and blood samples were taken from all mice after 42 days of treatment. Read More

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