6,477 results match your criteria Biological trace element research[Journal]


Histone Deacetylation in the Promoter of p16 Is Involved in Fluoride-Induced Human Osteoblast Activation via the Inhibition of Sp1 Binding.

Biol Trace Elem Res 2018 Jun 21. Epub 2018 Jun 21.

Department of Toxicology, School of Public Health, Guizhou Medical University, Guiyang, 550025, Guizhou, China.

Chronic fluorosis is a systemic condition which principally manifests as defects in the skeleton and teeth. Skeletal fluorosis is characterized by aberrant proliferation and activation of osteoblasts, however, the underlying mechanisms of osteoblast activation induced by fluoride are not fully understood. Therefore, we investigated the pathogenic mechanism of human primary osteoblast proliferation and activation in relation to histone acetylation of the promoter p16, a well-known cell cycle regulation-related gene. Read More

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Borax Supplementation Alleviates Hematotoxicity and DNA Damage in Rainbow Trout (Oncorhynchus mykiss) Exposed to Copper.

Biol Trace Elem Res 2018 Jun 21. Epub 2018 Jun 21.

Department of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, TR-25030, Erzurum, Turkey.

Heavy metals have harmful effects on health of both ecosystems and organisms to their accumulation ability. Copper (Cu) is an essential element for organism survival, but EPA considers Cu as a priority pollutant. On the other hand, boron has well-defined biological effects in living organisms including cytoprotection and genoprotection, although borax (BX) metabolism is poorly described in fish. Read More

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June 2018
1 Read

Changes in Liver Tissue Trace Element Concentrations During Hepatitis B Viral Infection Treatment.

Biol Trace Elem Res 2018 Jun 20. Epub 2018 Jun 20.

General Surgery Department, Mersin University, Mersin, Turkey.

Approximately 350-400 million people in the world have Hbs Ag (hepatitis B virus surface antigen) positivity. In the international guidelines, the permanent suppression of replication in chronic hepatitis B virus (HBV) infection therapy is reported as the primary therapeutic goal. Trace elements play a key role in liver diseases. Read More

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Selenium Deficiency Affects Immune Function by Influencing Selenoprotein and Cytokine Expression in Chicken Spleen.

Biol Trace Elem Res 2018 Jun 20. Epub 2018 Jun 20.

College of Veterinary Medicine*, Northeast Agricultural University, Harbin, 150030, People's Republic of China.

Se is an important bioelement essential for a healthy immune system. Dietary Se influences both innate and adaptive immune responses. However, the effects of Se deficiency in chicken spleen are still unknown; thus, we designed an experiment to study the role of Se in chicken spleen. Read More

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Selenium Rescues Aflatoxin B-Inhibited T Cell Subsets and Cytokine Levels in Cecal Tonsil of Chickens.

Biol Trace Elem Res 2018 Jun 20. Epub 2018 Jun 20.

College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, Sichuan, China.

Cecal tonsil is the largest peripheral lymphoid organ of the gut-associated lymphoid tissue executing immune function. To evaluate the protective effect of selenium (Se) on the cecal tonsil of chicken exposed to aflatoxin B (AFB), 144 1-day-old healthy Cobb chickens were randomly divided into four groups, and fed with basal diet (control group), 0.6 mg/kg AFB (AFB group), 0. Read More

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June 2018
2 Reads

Effects of Fluoride on Autophagy in Mouse Sertoli Cells.

Biol Trace Elem Res 2018 Jun 19. Epub 2018 Jun 19.

Shanxi Key Laboratory of Ecological Animal Science and Environmental Veterinary Medicine, College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, 030801, Shanxi, People's Republic of China.

Fluoride had been reported to damage the structure and function of testicular tissues and reproductive cells; however, the mechanisms underlying its toxicity remained unclear. Autophagy plays a key role in reproductive function. In this study, we aimed to investigate the effect of fluoride on autophagy in Sertoli cells. Read More

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Dietary Intake and Content of Some Micronutrients and Toxic Elements in Two Algerian Spices (Coriandrum sativum L. and Cuminum cyminum L.).

Biol Trace Elem Res 2018 Jun 17. Epub 2018 Jun 17.

Nuclear Research Centre of Birine, Po Box 180, Ain Oussera, 17200, Djelfa, Algeria.

This study presents the elemental concentration obtained in two Algerian spices (Coriandrum sativum L. and Cuminum cyminum L.) evaluated by instrumental neutron activation analysis (INAA), in order to highlight the importance of these spices as a potential source of micronutrients. Read More

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Blood Levels of Trace Elements in Children with Attention-Deficit Hyperactivity Disorder: Results from a Case-Control Study.

Biol Trace Elem Res 2018 Jun 16. Epub 2018 Jun 16.

Department of Child Health Care, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.

Some trace elements may participate in the pathogenesis of attention-deficit hyperactivity disorder (ADHD). This study aimed to investigate the trace element status of zinc (Zn), copper (Cu), iron (Fe), magnesium (Mg), and lead (Pb) in children with ADHD, and to compare them with normal controls. Associations between examined elements and SNAP-IV rating scores of ADHD symptoms were also assessed. Read More

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Heavy Metals in Indigenous Preparations Used for Sex Selection During Pregnancy in India.

Biol Trace Elem Res 2018 Jun 16. Epub 2018 Jun 16.

Public Health Foundation of India, Indian Institute of Public Health, Delhi, India.

Indigenous preparations (IPs) have evoked a considerable interest in alleviating infections and chronic diseases and improving wellbeing. While such formulations have been a part of traditional practice in several countries and many have been reviewed scientifically for their claims, several of them until date remain to be investigated. A class of IPs for sex selection by Indian pregnant women exists with an aim of begetting a male offspring. Read More

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Evaluation of Arsenic, Cadmium, Nickel and Lead in Common Spices in Pakistan.

Biol Trace Elem Res 2018 Jun 7. Epub 2018 Jun 7.

National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, 76080, Pakistan.

The quantitative assessments and daily intake of arsenic (As), cadmium (Cd), nickel (Ni) and lead (Pb) were conducted in the 26 common spices collected from the market of Hyderabad, Pakistan. Conventional acid digestion procedure was applied for dissolution of common spices and the contents of toxic elemental were determined by graphite furnace atomic absorption spectrometry. The conventional acid digestion method was validated by certified reference materials and standard addition. Read More

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June 2018
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Therapeutic Effect of Strontium Ranelate on Bone in Chemotherapy-Induced Osteopenic Rats via Increased Bone Volume and Reduced Bone Loss.

Biol Trace Elem Res 2018 Jun 7. Epub 2018 Jun 7.

Department of Bone and Soft Tissue Surgery, Liaoning Cancer Hospital & Institute, Cancer Hospital of China Medical University, No.44 Xiaoheyan Road, Dadong District, Shenyang, 110042, Liaoning Province, People's Republic of China.

The purpose of this study was to determine whether treatment with strontium ranelate (SrR) can restore bone mass and strength at a skeletal site with established osteopenia in chemotherapy-induced rats. Forty-five Sprague-Dawley male rats were randomly assigned to three study groups (n = 15 rats per group): normal rats (control group), osteopenic rats (chemo group), and osteopenic rats with SrR (chemo-SrR group). We chose a male rat model that mimicked a clinical setting by weekly intravenous injection of cyclophosphamide at 20 mg/kg. Read More

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June 2018
3 Reads

Levels of Toxic Elements in Tea Brands Commercialized in Egypt Using Optimized Dual-Pulsed Laser-Induced Spectral Analysis Spectrometer.

Biol Trace Elem Res 2018 Jun 6. Epub 2018 Jun 6.

Department of Environmental Health, College of Public Health, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

We report on qualitative and quantitative analyses of the toxic metal content in a series of 13 various commercial tea brands available in Egypt utilizing optimized double-pulse laser ablation spectroscopy (DP-LAS) and inductively coupled plasma-optical emission spectrometry (ICP-OES). The compositional analysis study utilizing the calibration, DP-LAS system, is based on the recorded accumulation spectra of the laser-created plasma plume. The toxic elements like lead, aluminum, and zinc that exist in the tea brands were accurately identified. Read More

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June 2018
4 Reads

Lanthanum Chloride Impairs the Blood-Brain Barrier Integrity by Reduction of Junctional Proteins and Upregulation of MMP-9 in Rats.

Biol Trace Elem Res 2018 Jun 6. Epub 2018 Jun 6.

Department of Toxicology, School of Public Health, China Medical University, #77 Puhe Road, Shenyang, 110122, People's Republic of China.

Lanthanum could cause cognitive impairment in children and rodent animals. The normal blood-brain barrier (BBB) integrity is essential for protecting the brain from systemic toxins and maintaining the homeostasis for proper neuronal function. BBB dysfunction has been implicated as a potential mechanism of heavy metal-induced neurotoxicity. Read More

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June 2018
5 Reads

Effect of Boron on the Repair of Osteochondral Defect and Oxidative Stress in Rats: an Experimental Study.

Biol Trace Elem Res 2018 Jun 4. Epub 2018 Jun 4.

Department of Surgery, Faculty of Veterinary Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.

The aim of this study was to investigate the effect of boron on the repair of osteochondral defect and also on some antioxidant and oxidant parameters of both cartilage tissue and blood. A total of 24 adult male Wistar rats weighing between 350 and 400 g were used in the study. Animals were randomly divided into control (n = 8), boron (n = 8) and hyaluronic acid (HA) groups (n = 8). Read More

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June 2018
2 Reads

Hematobiochemical Disturbances and Oxidative Stress After Subacute Manganese Chloride Exposure and Potential Protective Effects of Ebselen in Rats.

Biol Trace Elem Res 2018 Jun 2. Epub 2018 Jun 2.

Department of Clinical Pathology, Faculty of Veterinary Medicine, Zagazig University, 1 Alzeraa Street, Zagazig, Sharkia Province, 44511, Egypt.

The present study aimed to detect the possible disturbances induced by subacute exposure to manganese chloride (MnCl) on some biomarkers of hematology, clinical chemistry and oxidative stress, serum iron homeostasis, and ferritin status beside the histopathological alterations in hepatic and renal tissues, and the potential protective effects of ebselen on the Mn toxicity were also evaluated. Forty-eight rats were divided into four groups: Group 1 was used as a control. Groups 2, 3, and 4 were administered of ebselen as a single protective dose (15 mg/kg BW) intraperitoneal, daily manganese chloride (50 mg/kg BW) orally, and ebselen plus manganese chloride, respectively. Read More

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June 2018
2 Reads

Correction to: Effect of Selenium on Lipid and Amino Acid Metabolism in Yeast Cells.

Biol Trace Elem Res 2018 Jun 1. Epub 2018 Jun 1.

Faculty of Food Sciences, Department of Biotechnology, Microbiology and Food Evaluation, Warsaw University of Life Sciences - SGGW, Nowoursynowska 159 C, 02-776, Warsaw, Poland.

The authors forgot to include the following information in Materials and Methods. Read More

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Selenium Biofortification and Antioxidant Activity in Cordyceps militaris Supplied with Selenate, Selenite, or Selenomethionine.

Biol Trace Elem Res 2018 May 31. Epub 2018 May 31.

College of Resources and Environmental Sciences, China Agricultural University, Beijing, 100193, China.

Selenium (Se) is an essential trace element with multiple functions that may help mitigate adverse health conditions. Cordyceps militaris is an edible mushroom with medicinal properties. The experiment was conducted under artificial cultivation, with five Se concentrations (0, 5, 10, 20, and 40 μg g) and three forms of Se (selenate, selenite, and selenomethionine). Read More

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Are There as Many Essential and Non-essential Minerals in Hydroponic Strawberry (Fragaria ananassa L.) Compared to Those Grown in Soil?

Biol Trace Elem Res 2018 May 30. Epub 2018 May 30.

Division of Applied Life Science (BK21 Plus), Gyeongsang National University, Jinju, 52828, Republic of Korea.

The present study aims to compare the contents of minerals (essential major-K, Ca, Mg, Na, P, S; essential trace-Fe, Mn, Zn, Cu, B, Mo, As, Se, Ni, V, Cr, Co; non-essential-Sn, Ga, Li, Be, Rb, Sr, Al, Pd, Cd, Hg, Pb, Ge) in strawberry (stem, leaf, and fruit) cultivated in two different cultivation systems, soil and hydroponic. The concentrations of 30 minerals in the acid-digested strawberry samples were determined by ICP-MS and ICP-OES. Hydroponic strawberry (leaf > fruit > stem) indicated higher values for most minerals which were below the plant toxicity levels. Read More

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Co-exposure to an Aryl Hydrocarbon Receptor Endogenous Ligand, 6-Formylindolo[3,2-b]carbazole (FICZ), and Cadmium Induces Cardiovascular Developmental Abnormalities in Mice.

Biol Trace Elem Res 2018 May 28. Epub 2018 May 28.

Department of Pharmacology and Toxicology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.

6-Formylindolo[3,2-b]carbazole (FICZ) is a signal substance and an endogenous activator of aryl hydrocarbon receptor (AHR). Cadmium (Cd) is an environmental pollutant that can activate both AHR and Wnt/β-catenin signaling pathways. We aimed to determine how dysregulated signaling through AHR-Wnt/β-catenin cross-talk can influence mice heart development. Read More

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May 2018
2 Reads
1.75 Impact Factor

Green Engineered Biomolecule-Capped Silver Nanoparticles Fabricated from Cichorium intybus Extract: In Vitro Assessment on Apoptosis Properties Toward Human Breast Cancer (MCF-7) Cells.

Biol Trace Elem Res 2018 May 28. Epub 2018 May 28.

Department of Biology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.

The current experiment reveals the anticancer properties of silver nanoparticles (AgNPs) synthesized using aqueous leaf extract of Cichorium intybus, a significant medicinal plant. The characteristics of AgNPs were continuously studied by powder X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), zeta potential, transmission electron microscopy (TEM), scanning electron microscopy (SEM), and energy-dispersive spectroscopy (EDS) analysis. Current microscopic results show that produced AgNPs were spherical in shape with an average size of 17. Read More

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May 2018
1 Read

Influence of Chronic Toxicity, Lipid Metabolism, Learning and Memory Ability, and Related Enzyme in Sprague-Dawley Rats by Long-Term Chromium Malate Supplementation.

Biol Trace Elem Res 2018 May 24. Epub 2018 May 24.

School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, Jiangsu, China.

In our previous study, chromium malate is beneficial for type 2 diabetic rats in control glycometabolism and lipid metabolism. The present study was designed to observe the chronic toxicity, lipid metabolism, learning and memory ability, and related enzymes of chromium malate in rats during the year. The results showed that pathological, toxic, feces, and urine of chromium malate (at daily doses of 10. Read More

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May 2018
1 Read

Trivalent Chromium Supplementation Ameliorates Oleic Acid-Induced Hepatic Steatosis in Mice.

Biol Trace Elem Res 2018 May 24. Epub 2018 May 24.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.

Trivalent chromium [Cr(III)] is recognized as an essential trace element for human health, whereas its effect on hepatic lipid metabolism has not yet been fully understood. This study aimed to investigate the beneficial effects and potential mechanisms of Cr(III) on hepatic steatosis in an oleic acid (OA) induced mice model. Mice were fed with high OA for 12 weeks to induce lipid accumulation, and co-administrated with Cr(III) supplementation. Read More

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May 2018
2 Reads

Effects of Restoring the Primary Dentition with Stainless-Steel Crowns on Children's Salivary Nickel and Chromium Levels, and the Associations with Saliva pH: a Preliminary Before-After Clinical Trial.

Biol Trace Elem Res 2018 May 23. Epub 2018 May 23.

Department of Dental Anatomy, Dental Faculty, Azad University of Medical Sciences, Tehran, Iran.

Nickel and chromium existing in stainless-steel crowns (SSCs, used in pediatric dentistry) might be cytotoxic and allergenic. However, no in vivo studies have examined their salivary levels in children using SSCs, or in young children without SSCs. Also, the effect of acidity on metal ion release has not yet been evaluated in any previous in vivo studies in the whole literature. Read More

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May 2018
2 Reads

Calcium Channels, Rho-Kinase, Protein Kinase-C, and Phospholipase-C Pathways Mediate Mercury Chloride-Induced Myometrial Contractions in Rats.

Biol Trace Elem Res 2018 May 21. Epub 2018 May 21.

Experimental Pharmacology Laboratory, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura, 281001 (U.P.), India.

Adverse effects of mercury on female reproduction are reported; however, its effect on myogenic activity of uterus and mechanism thereof is obscure. Present study was undertaken to unravel the mechanistic pathways of mercuric chloride (HgCl)-induced myometrial contraction in rats. Isometric tension in myometrial strips of rats following in vitro exposure to HgCl was recorded using data acquisition system-based physiograph. Read More

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May 2018
1 Read

Dietary Intake and Content of Cu, Mn, Fe, and Zn in Selected Cereal Products Marketed in Poland.

Biol Trace Elem Res 2018 May 18. Epub 2018 May 18.

Department of Bromatology and Food Physiology, University of Life Sciences in Lublin, Akademicka 13, 20-950, Lublin, Poland.

This paper aims to verify whether cereal products are a good source of Cu, Mn, Fe, and Zn in the diets of Poles. The study material comprised of 445 cereal products including baked goods, breakfast cereals and groats, pasta, and rice. Products that required culinary treatment (pasta, groats, rice) were boiled in drinking quality water as recommended by the producer. Read More

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May 2018
1 Read

Preconcentration and Determination of Trace Nickel and Cobalt in Milk-Based Samples by Ultrasound-Assisted Cloud Point Extraction Coupled with Flame Atomic Absorption Spectrometry.

Biol Trace Elem Res 2018 May 18. Epub 2018 May 18.

Faculty of Sciences, Department of Chemistry/Analytical Chemistry, University of Cumhuriyet, TR-58140, Sivas, Turkey.

In this study, ultrasound-assisted cloud point extraction (UA-CPE) method was developed for the determination of Ni(II) and Co(II) in milk-based products. After extraction and preconcentration, the Ni(II) and Co(II) contents of samples were determined by flame atomic absorption spectrometry (FAAS). After their complexation with hydroxy naphthol blue (HNB) in the presence of cationic surfactant, CTAB at pH 4. Read More

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May 2018
2 Reads

Mercury Involvement in Neuronal Damage and in Neurodegenerative Diseases.

Biol Trace Elem Res 2018 May 18. Epub 2018 May 18.

IRCCS Centro Neurolesi "Bonino Pulejo", Via Provinciale Palermo, Contrada Casazza, 98124, Messina, Italy.

Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis are characterized by a chronic and selective process of neuronal cell death. Although the causes of neurodegenerative diseases remain still unknown, it is now a well-established idea that more factors, such as genetic, endogenous, and environmental, are involved. Among environmental causes, the accumulation of mercury, a heavy metal considered a toxic agent, was largely studied as a probable factor involved in neurodegenerative disease course. Read More

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May 2018
1 Read

Requirement of TGFβ Signaling for Effect of Fluoride on Osteoblastic Differentiation.

Biol Trace Elem Res 2018 May 16. Epub 2018 May 16.

School of Pharmaceutical Sciences, Jilin University, 1163 Xinmin Street, Changchun, Jilin Province, 130021, People's Republic of China.

Research focused on transforming growth factor β (TGFβ) signaling in osteoblast is gradually increasing, whereas literature is rare in terms of fluorosis. This work aimed to investigate how TGFβ signaling participated in regulation of the osteoblast by different doses of fluoride treatment. Bone marrow stem cells (BMSCs) were developed into osteoblastic cells and exposed to 1, 4, and 16 mg/L F with and without 10 ng/mL of TGFβ. Read More

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May 2018
1 Read

Heme and Non-heme Iron on Growth Performances, Blood Parameters, Tissue Mineral Concentration, and Intestinal Morphology of Weanling Pigs.

Biol Trace Elem Res 2018 May 16. Epub 2018 May 16.

Key Laboratory of Animal Nutrition & Feed Science, College of Animal Science, Zhejiang University, Hangzhou, 310058, China.

This experiment was conducted to evaluate the effects of heme and non-heme iron sources on growth performances, blood parameters, tissue mineral concentration, and intestinal morphology in weanling pigs. At 25 days of age, 32 newly weaned piglets (Duroc × Landrace × Yorkshire; 8.66 ± 0. Read More

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Selenium Ameliorates AFBInduced Excess Apoptosis in Chicken Splenocytes Through Death Receptor and Endoplasmic Reticulum Pathways.

Biol Trace Elem Res 2018 May 16. Epub 2018 May 16.

College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, Sichuan, People's Republic of China.

Aflatoxin B (AFB) can cause hepatotoxicity, genotoxicity, and immunosuppressive effects for a variety of organisms. Selenium (Se), as an essential nutrient element, plays important protective effects against cell apoptosis induced by AFB. This research aimed to reveal the ameliorative effects of selenium on AFB-induced excess apoptosis in chicken splenocytes through death receptor and endoplasmic reticulum pathways in vivo. Read More

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May 2018
3 Reads

Carnosine and Histidine Supplementation Blunt Lead-Induced Reproductive Toxicity through Antioxidative and Mitochondria-Dependent Mechanisms.

Biol Trace Elem Res 2018 May 16. Epub 2018 May 16.

Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Lead (Pb)-induced reproductive toxicity is a well-characterized adverse effect associated with this heavy metal. It has been found that Pb exposure is associated with altered spermatogenesis, increased testicular degeneration, and pathological sperm alterations. On the other hand, it has been reported that Pb-induced reproductive toxicity is associated with increased reactive oxygen species (ROS) formation and diminished antioxidant capacity in the reproductive system. Read More

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May 2018
2 Reads

Zinc Supplementation Ameliorates Diabetic Cataract Through Modulation of Crystallin Proteins and Polyol Pathway in Experimental Rats.

Biol Trace Elem Res 2018 May 13. Epub 2018 May 13.

Department of Biochemistry, CSIR - Central Food Technological Research Institute, Mysore, 570 020, India.

Non-enzymatic glycation of lens proteins and elevated polyol pathway in the eye lens have been the characteristic features of a diabetic condition. We have previously reported the benefits of zinc supplementation in reducing hyperglycemia and associated metabolic abnormalities and oxidative stress in diabetic rats. The current study explored whether zinc supplementation protects against cataractogenesis through modulation of glycation of lens proteins, elevated polyol pathway, oxidative stress, and proportion of different heat shock proteins in the eye lens of diabetic rats. Read More

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May 2018
1 Read

Ecological and Human Health Risk Assessment of Heavy Metal Content of Atmospheric Dry Deposition, a Case Study: Kermanshah, Iran.

Biol Trace Elem Res 2018 May 12. Epub 2018 May 12.

Department of the Environment, College of Basic Sciences, Hamedan Branch, Islamic Azad University, Hamedan, Iran.

The present study was intended to investigate the ecological and human health risk of cobalt, nickel, and vanadium in the atmospheric dry deposition of the Kermanshah city, Iran, in 2015. Totally 54 samples of atmospheric dry deposition were collected from the three regions of the city with different traffic intensity, and after acid digestion of the samples with ultrapure concentrated HNO, the total contents of the metals were determined using inductively coupled plasma optical emission spectrometer (ICP-OES). Also, all statistical analyses were performed using the SPSS statistical package. Read More

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Determination of Seasonal Vitamin and Mineral Contents of Sea Bream (Sparus aurata L., 1758) Cultured in Net Cages in Central Black Sea Region.

Biol Trace Elem Res 2018 May 12. Epub 2018 May 12.

Faculty of Fisheries and Aquatic Science, Department of Aquaculture, Sinop University, Sinop, Turkey.

This study aimed to determine the seasonal vitamin and mineral contents of sea bream (Sparus aurata) cultured in net cages in Central Black Sea region. The average seasonal A, D, and E vitamins values in fish meat were between 0.27 ± 0. Read More

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May 2018
2 Reads

Association Between Selenium and Malondialdehyde as an Efficient Biomarker of Oxidative Stress in Infantile Cardiac Surgery.

Biol Trace Elem Res 2018 May 12. Epub 2018 May 12.

Group of Spectroscopy and Bioinformatics Applied Biodiversity and Health, School of Medicine, Federal University of Mato Grosso do Sul-FAMED/UFMS, Cidade Universitária, Box 549, Campo Grande, MS, 79070-900, Brazil.

The present work describes a method to quantify the level of oxidative stress in infantile cardiac surgery. Fifteen patients, 6 girls and 9 boys, aged between 3 months and 16 years were divided into three groups. The first group sought to quantify the oxidative stress from differing concentrations of selenium. Read More

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May 2018
1 Read

Selenium Nanoparticles Induce the Chemo-Sensitivity of Fluorouracil Nanoparticles in Breast and Colon Cancer Cells.

Biol Trace Elem Res 2018 May 11. Epub 2018 May 11.

Hormones Department, Medical Research Division, National Research Centre, P.O. 12622, Dokki, Giza, Egypt.

Drug resistance is a major challenge of breast and colon cancer therapies leading to treatment failure. The main objective of the current study is to investigate whether selenium nanoparticles (nano-Se) can induce the chemo-sensitivity of 5-fluorouracil (FU)-encapsulated poly (D, L-lactide-co-glycolide) nanoparticles (nano-FU) in breast and colon cancer cell lines. Nano-Se and nano-FU were synthesized and characterized, then applied individually or in combination upon MCF7, MDA-MB-231, HCT 116, and Caco-2 cancerous cell lines. Read More

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Positive PCNA and Ki-67 Expression in the Testis Correlates with Spermatogenesis Dysfunction in Fluoride-Treated Rats.

Biol Trace Elem Res 2018 May 10. Epub 2018 May 10.

College of Animal Science and Technology, Henan University of Science and Technology, Kaiyuan Avenue 263, Luoyang, 471000, Henan, People's Republic of China.

The present study aimed to evaluate the effect of fluoride (F) on spermatogenesis in male rats. F at 50 and 100 mg/L was administered for 70 days, after which the testicular and epididymis tissues were collected to observe the histopathological structure under a light microscope. The ultrastructure of the testis and sperm was also examined via transmission electron microscopy. Read More

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May 2018
3 Reads

Toxicological Aspect of Some Selected Medicinal Plant Samples Collected from Djelfa, Algeria Region.

Biol Trace Elem Res 2018 May 10. Epub 2018 May 10.

Neutron Activation Analysis Department NAA, Nuclear Research Centre of Birine, Po Box 180, Ain Oussera, 17200, Djelfa, Algeria.

Instrumental neutron activation analysis (INAA) has been used to determine the concentration of some toxic chemical elements in a variety of aromatic plants samples collected from Djelfa region. In the present work, eight medicinal plants were examined, such as Artemisia herba-alba Asso., Artemisia compestris L. Read More

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May 2018
9 Reads

Effects of Humic Acids in Chronic Lead Poisoning.

Biol Trace Elem Res 2018 May 10. Epub 2018 May 10.

Department of Medical and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Tr. SNP 1, 040 66, Košice, Slovak Republic.

Chronic exposure to lead causes disruption to energy production mechanisms and tissue damage, in particular through its binding to thiol groups and competition for zinc binding sites. We investigated the possibility of preventing the consequences of chronic lead poisoning by administration of three different doses of humic acids (HAs) into feed with the aim of establishing an effective HA dose. During the 10-week experiment, a sub-lethal dose of lead acetate was given to rats during the first 5 weeks, with continuous administration of HA over 10 weeks. Read More

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May 2018
6 Reads

Perinatal Exposure to Arsenic in Drinking Water Alters Glutamatergic Neurotransmission in the Striatum of C57BL/6 Mice.

Biol Trace Elem Res 2018 May 10. Epub 2018 May 10.

Collage of Pharmacy, Keimyung University, Daegu, 42601, Republic of Korea.

Although exposure to arsenic (As) induces developmental neurotoxicity, there is a lack of data regarding its specific effects on glutamatergic neurotransmission in offspring from dams exposed to As during gestation and lactation. In this study, the body weight, glutamate content, and expression of vesicular glutamate transporter 2 (VGLUT2) and metabotropic glutamate receptors mGluR2 and mGluR3 was examined in the striatum of offspring following treatment of the dams with As (10 or 100 mg/L NaAsO in drinking water). At postnatal day 21, body weight was decreased significantly, whereas the glutamate content in the striatum of offspring in the 100-mg/L As group were not significantly different from those in the control group. Read More

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May 2018
2 Reads

Zinc and Metallothionein in the Development and Progression of Dental Caries.

Biol Trace Elem Res 2018 May 9. Epub 2018 May 9.

Department of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Jalan Universiti, 50603, Kuala Lumpur, Malaysia.

Chronic oxidative stress and reactive oxygen species (ROS) in oral cavity as well as acidic pH on dental enamel surface due to the metabolic activities of bacterial plaque are the major contributors in the development and progression of dental caries. Along with other factors, deposition or dissolution Ca and Mg mostly determines the re- or demineralization of dental enamel. Zn plays an important role for both Ca and Mg bioavailability in oral cavity. Read More

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Du-Zhong (Eucommia ulmoides Oliv.) Cortex Extract Alleviates Lead Acetate-Induced Bone Loss in Rats.

Biol Trace Elem Res 2018 May 9. Epub 2018 May 9.

College of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong, 723000, Shaanxi, China.

The purpose of this study was to evaluate the protective effect of Du-Zhong cortex extract (DZCE) on lead acetate-induced bone loss in rats. Forty female Sprague-Dawley rats were randomly divided into four groups: group I (control) was provided with distilled water. Group II (PbAc) received 500 ppm lead acetate in drinking water for 60 days. Read More

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May 2018
1 Read

Identification of Biomarkers of Mercury Contamination in Brachyplatystoma filamentosum of the Madeira River, Brazil, Using Metalloproteomic Strategies.

Biol Trace Elem Res 2018 May 8. Epub 2018 May 8.

School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.

Predator fish can accumulate high levels of mercury, which qualifies them as potential indicators of this toxic metal. The predatory species Brachyplatystoma filamentosum, popularly known as filhote, is among the most consumed species in the Brazilian Amazon. Continuing the metalloproteomic studies of mercury in Amazonian fishes that have been developed in the last 5 years, the present paper provides the data of protein characterization associated with mercury in muscle and liver samples of filhote (Brachyplatystoma filamentosum) collected in the Madeira River, Brazilian Amazon. Read More

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May 2018
1 Read

Role of Melatonin in Aluminum-Related Neurodegenerative Disorders: a Review.

Biol Trace Elem Res 2018 May 7. Epub 2018 May 7.

Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201, Reus, Catalonia, Spain.

Aluminum (Al), a potentially neurotoxic element, provokes various adverse effects on human health such as dialysis dementia, osteomalacia, and microcytic anemia. It has been also associated with serious neurodegenerative diseases such as Alzheimer's disease (AD), amyotrophic lateral sclerosis, and Parkinsonism dementia of Guam. The "aluminum hypothesis" of AD assumes that the metal complexes can potentiate the rate of aggregation of amyloid-β (Aβ), enhancing the toxicity of this peptide, and being able of contributing to the pathogenesis of AD. Read More

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Effect of Selenium Nanoparticle Supplementation on Tissue Inflammation, Blood Cell Count, and IGF-1 Levels in Spinal Cord Injury-Induced Rats.

Biol Trace Elem Res 2018 May 5. Epub 2018 May 5.

Department of Veterinary Surgery and Radiology, Faculty of Veterinary Medicine, Shahrekord University, P.O. 88186-34141, Shahrekord, Iran.

Selenium is known to be a neuroprotective agent in respect to a number of neuronal diseases and pain. The aim of this study was to evaluate the neuroprotective effect of the oral administration of selenium nanoparticles in rats with spinal cord injury (SCI). Forty adult female rats were randomly assigned to two equal groups as experimental and control. Read More

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May 2018
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A Comparative Study of Iodized Salt Programs: Shanghai and Switzerland.

Biol Trace Elem Res 2018 May 5. Epub 2018 May 5.

Institute of Iodine Deficiency Disorders Prevention and Control, Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang, China.

Both Shanghai and Switzerland are developed regions with long-standing salt iodization programs and periodic monitoring. However, the two regions have their own approach to the implementation of the iodized salt policy. In Shanghai, monitoring was carried out every few years, using probability-proportional-to-size sampling technique to select 30 sampling units. Read More

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May 2018
3 Reads

The Safety Assessment of Toxic Metals in Commonly Used Pharmaceutical Herbal Products and Traditional Herbs for Infants in Jordanian Market.

Biol Trace Elem Res 2018 May 5. Epub 2018 May 5.

Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, 130, Amman, 11733, Jordan.

The objective of this study was to assess the levels of contamination by toxic metals (Pb, Al, Ni, Cd and As) that may be present in 25 infant pharmaceutical herbal products and 15 traditional herbs in Jordan. Both products and medicinal herbs are currently prescribed by paediatricians. They are available as over-the-counter medicines and are sold the in herbal market, ensuring easy accessibility for parents. Read More

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May 2018
4 Reads

Moringa oleifera Leaves Extract Protects Titanium Dioxide Nanoparticles-Induced Nephrotoxicity via Nrf2/HO-1 Signaling and Amelioration of Oxidative Stress.

Biol Trace Elem Res 2018 May 4. Epub 2018 May 4.

Department of Toxicology and Forensic Medicine, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt.

The efficacy of Moringa oleifera leaf extract (MO) in alleviating nephrotoxicity induced by titanium dioxide nanoparticles (TiO NPs) was studied. Rats were divided into four groups. Group I received distilled water. Read More

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May 2018
2 Reads

Effect of Cooking on Speciation and In Vitro Bioaccessibility of Hg and As from Rice, Using Ordinary and Pressure Cookers.

Biol Trace Elem Res 2018 May 3. Epub 2018 May 3.

National Key Laboratory of Water Environment Simulation and Pollution Control, South China Institute of Environmental Sciences, Ministry of Environmental Protection, Guangzhou, 510655, China.

Rice is the most widely consumed staple food for a large part of the world's human population, and owing to environmental pollution, it is a major source of human exposure to mercury (Hg) and arsenic (As). We evaluated the impact of cooking on the speciation and bioaccessibility of Hg and As from rice in this study. Results show that the dominant Hg and As species in rice from Guangzhou market in China were their inorganic forms (iHg and iAs), respectively. Read More

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May 2018
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Health Risk Assessment and Urinary Excretion of Children Exposed to Arsenic through Drinking Water and Soils in Sonora, Mexico.

Biol Trace Elem Res 2018 May 2. Epub 2018 May 2.

Departamento de Recursos Naturales, Instituto Tecnológico de Sonora, 5 de Febrero 818 Sur, 85000, Cd. Obregón, Sonora, Mexico.

Environmental arsenic exposure is associated with increased risk of non-cancerous chronic diseases and a variety of cancers in humans. The aims of this study were to carry out for the first time a health risk assessment for two common arsenic exposure routes (drinking water and soil ingestion) in children living in the most important agricultural areas in the Yaqui and Mayo valleys in Sonora, Mexico. Drinking water sampling was conducted in the wells of 57 towns. Read More

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May 2018
2 Reads