Search our Database of Scientific Publications and Authors

I’m looking for a

    6273 results match your criteria Biological trace element research[Journal]

    1 OF 126

    Correction to: Potentiometric Determination of Fluoride Concentration in Beers.
    Biol Trace Elem Res 2017 Nov 21. Epub 2017 Nov 21.
    Área de Fisioterapia, Facultad de Ciencias de la Salud, Universidad de La Laguna, Campus de Ofra s/n, 38071, Santa Cruz de Tenerife, Spain.
    The original version of the article unfortunately contained a mistake. The first author Inmaculada Gutiérrez was omitted. Read More

    Effects of Arsenic Trioxide on INF-gamma Gene Expression in MRL/lpr Mice and Human Lupus.
    Biol Trace Elem Res 2017 Nov 20. Epub 2017 Nov 20.
    Department of Rheumatology, The First Affiliated Hospital of Wenzhou Medical University, Nan Bai Xiang Street, Ouhai District, Wenzhou, Zhejiang Province, 325000, China.
    Arsenic trioxide (As2O3; ATO), a traditional Chinese medicine, is used to treat patients with acute promye-locytic leukemia, while its application for treatment of systemic lupus erythematosus (SLE) is still under evaluation. The high expression of INF-gamma (INF-γ) is a primary pathogenic factor in SLE. It is found that ATO can reduce INF-γ expression levels in lupus-prone mice, whereas it is not clear whether ATO has the same effect on SLE patients. Read More

    Health Risk Contamination of Heavy Metals in Yolk and Albumen of Duck Eggs Collected in Central and Western Thailand.
    Biol Trace Elem Res 2017 Nov 18. Epub 2017 Nov 18.
    Center for Duck Health Science, Faculty of Veterinary Medicine, Kasetsart University Kamphaeng Saen Campus, Nakhon Pathom, 73140, Thailand.
    Two hundred duck egg samples were collected from 20 farms in Central and Western Thailand. The levels of Zn, Co, Mn, Fe, and Cr in yolks were found significantly higher than in albumen, whereas the levels of Cd and Cu contaminations in egg albumen were significantly higher than in yolks. The mean level of Pb contamination in whole eggs was 4. Read More

    Comparative Hair Trace Element Profile in the Population of Sakhalin and Taiwan Pacific Islands.
    Biol Trace Elem Res 2017 Nov 17. Epub 2017 Nov 17.
    Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya St., 6, Moscow, Russian Federation, 105064.
    The objective of the current study is to perform a comparative analysis of hair trace element content in 393 apparently healthy adults living in Taipei, Taiwan, Republic of China (94 women and 46 men) and Yuzhno-Sakhalinsk, Sakhalin, Russia (186 women and 67 men). The obtained data indicate that Yuzhno-Sakhalinsk inhabitants were characterized by significantly higher hair Co, Cr, Mn, and V levels, exceeding the respective Taipei values by a factor of 3, 2, 7, and 5, respectively (all p < 0.001). Read More

    Effect of Cys, GSH, and pH on Mercury Release from Tibetan Medicine Zuotai, β-HgS, and α-HgS in Artificial Gastrointestinal Juices.
    Biol Trace Elem Res 2017 Nov 12. Epub 2017 Nov 12.
    Qinghai Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xinning Road 23, Xining, Qinghai, 810008, China.
    Zuotai, also named as "gTso thal", a known Tibetan medicinal mixture containing insoluble cubic crystal mercuric sulfide (β-HgS), has been used to treat diseases with long history. The mercury release ratio from Zuotai in gastrointestinal environment is one determinant factor for its bioavailability and biological effect. However, the information is still scarce now. Read More

    Protective Effect of Agaricus blazei Polysaccharide Against Cadmium-Induced Damage on the Testis of Chicken.
    Biol Trace Elem Res 2017 Nov 10. Epub 2017 Nov 10.
    Department of Clinical Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, China.
    Cadmium (Cd) exposure can cause reproductive toxicity through oxidative stress and inflammatory response. A polysaccharide extract of the edible mushroom Agaricus blazei Murill has been isolated and exhibits antioxidant activity and immunoregulatory effect. The aim of this study was to investigate the protective role of Agaricus blazei polysaccharide (ABP) against Cd-induced damage in chicken testis through enhancing antioxidant activity and alleviating inflammatory response. Read More

    The Effects of Magnesium and Zinc Co-Supplementation on Biomarkers of Inflammation and Oxidative Stress, and Gene Expression Related to Inflammation in Polycystic Ovary Syndrome: a Randomized Controlled Clinical Trial.
    Biol Trace Elem Res 2017 Nov 10. Epub 2017 Nov 10.
    Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, IR, Iran.
    Magnesium and zinc are known to exert multiple beneficial effects including anti-inflammatory and antioxidant actions. To our knowledge, data on the effects of magnesium and zinc co-supplementation on biomarkers of inflammation and oxidative stress and gene expression related to inflammation in subjects of polycystic ovary syndrome (PCOS) are scarce. This study was conducted to evaluate the effects of magnesium and zinc co-supplementation on biomarkers of inflammation and oxidative stress and gene expression related to inflammation in subjects with PCOS. Read More

    Effect of Application of Fe-Glycinate Chelate in Diet for Broiler Chickens in an Amount Covering 50 or 25% of the Requirement on Physical, Morphometric and Strength Parameters of Tibia Bones.
    Biol Trace Elem Res 2017 Nov 9. Epub 2017 Nov 9.
    Institute of Animal Nutrition and Bromatology, University of Life Sciences in Lublin, Akademicka 13, 20-950, Lublin, Poland.
    The purpose of the work was to check whether the application of Fe-glycinate chelate in mixtures fed to poultry in an amount covering 50 or 25% of the requirement would decrease the physical, morphometric and strength parameters of tibia bones in male Ross-308 broiler chickens in comparison to groups receiving Fe in an amount covering 100% of the requirement in the form of glycinate chelate or sulphate. It was found that the results for chickens from groups receiving Fe chelate covering 50 or 25% of the requirement were generally not lower than in the sulphate group and were higher than in the group receiving Fe in the amount covering 100% of the requirement. The presented results indicate that the standard requirement for Fe (40 mg kg(-1) feed) as recommended by producers of Ross chickens may be too high if glycinate chelate is the source of Fe. Read More

    Effect of Chromium Nanoparticles on Physiological Stress Induced by Exogenous Dexamethasone in Japanese Quails.
    Biol Trace Elem Res 2017 Nov 2. Epub 2017 Nov 2.
    Department of Animal and Poultry Science, College of Aburaihan, University of Tehran, Pakdasht, Theran, P.O. Box: 11365//7117, Tehran, Iran.
    Chromium (Cr), as an essential trace element, plays a critical role in carbohydrate, protein, and lipid metabolism in animals. It has been suggested that the beneficial effects of Cr increase by environmental stresses, which lead to greater Cr effects on stressed animals. The objective of the present study was to evaluate the response of physiologically stressed Japanese quails (Coturnix japonica) to dietary chromium nanoparticle (Nano-Cr) supplementation. Read More

    Nutrient Composition of Three Mangulica Pork Cuts from Serbia.
    Biol Trace Elem Res 2017 Nov 2. Epub 2017 Nov 2.
    Faculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, Belgrade, 11000, Serbia.
    The purpose of this study was to analyze and evaluate the levels of essential elements (Mn, Fe, Cu, Zn, and Se) and proximate composition (moisture, protein, fat, and ash) of three pork cuts (loin, hind leg, and shoulder) from free-range Mangulica pigs from Serbia. Essential elements were determined by inductively coupled plasma mass spectrometry (ICP-MS). Shoulder contained the highest levels of essential elements (Mn, 0. Read More

    Correction to: Mercury Exposure: Protein Biomarkers of Mercury Exposure in Jaraqui Fish from the Amazon Region.
    Biol Trace Elem Res 2017 Nov 2. Epub 2017 Nov 2.
    Institute of Bioscience of Botucatu, São Paulo State University (UNESP), Rubião Júnior, Botucatu, São Paulo, 18618-970, Brazil.
    In the affiliation section, Luiz Fabricio Zara's affiliation "Pontifical Catholic University of Goiás (PUC), Goiânia, GO, Brazil" was incorrect. The correct affiliation is College of Planaltina, UnB - University of Brasília, Distrito Federal, Brazil. Read More

    Ameliorative Effects of Selenium on Cadmium-Induced Injury in the Chicken Ovary: Mechanisms of Oxidative Stress and Endoplasmic Reticulum Stress in Cadmium-Induced Apoptosis.
    Biol Trace Elem Res 2017 Oct 31. Epub 2017 Oct 31.
    College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
    Despite the well-established toxicity of cadmium (Cd) to animals and the ameliorative effects of selenium (Se), some specific mechanisms in the chicken ovary are not yet clarified. To explore the mechanism by which the toxicity effect of Cd is induced and explore the effect of supranutritional Se on Cd toxicity in female bird reproduction, forty-eight 50-day-old Isa Brown female chickens were divided randomly into four groups. Group I (control group) was fed the basic diet containing 0. Read More

    Selenium and Zinc against Aβ25-35-Induced Cytotoxicity and Tau Phosphorylation in PC12 Cells and Inhibits γ-cleavage of APP.
    Biol Trace Elem Res 2017 Oct 28. Epub 2017 Oct 28.
    Department of Preventive Medicine, Medical College, Yanbian University, Yanji, Jilin, 133002, China.
    Amyloid beta (Aβ) is the main component of the amyloid plaques that accumulate in the brains of Alzheimer patients. The present study was conducted to investigate whether the combined treatment with selenium (Se) and zinc (Zn) offers more beneficial effects than that provided by either of them alone in reversing Aβ25-35-induced neurotoxicity in PC12 cells. Cells were pretreated with 0. Read More

    Effects of Dietary Supplementation of Zinc Oxide and Zinc Methionine on Layer Performance, Egg Quality, and Blood Serum Indices.
    Biol Trace Elem Res 2017 Oct 28. Epub 2017 Oct 28.
    Department of Poultry Production, Faculty of Agriculture, Assiut University, Assiut, 71515, Egypt.
    The objective of this study was to evaluate the effectiveness of dietary zinc oxide (ZnO) and zinc methionine (Zn-Met) supplementation on layer performance, quality of egg, some blood constituents, and oxidative status in blood of laying hens. A total of 120 laying hens (Hisex Brown) 22-week-old were indiscriminately allotted into five groups of 24 hens with six replications (four birds/replicate). A complete randomized design experiment was performed including control (basal diet), two levels of ZnO (50 and 100 mg/kg basal diet), and two levels of Zn-Met (50 and 100 mg/kg basal diet) through 22 to 34 weeks of age. Read More

    Zoledronic Acid, Bevacizumab and Dexamethasone-Induced Apoptosis, Mitochondrial Oxidative Stress, and Calcium Signaling Are Decreased in Human Osteoblast-Like Cell Line by Selenium Treatment.
    Biol Trace Elem Res 2017 Oct 28. Epub 2017 Oct 28.
    Department of Biophysics, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey.
    Increased intracellular free calcium ion (Ca(2+)) concentration induces excessive oxidative stress and apoptosis. Medical procedures such as zoledronic acid (Zol), bevacizumab (Bev), and dexamethasone (Dex) are usually used in the treatment of bone diseases (osteoporosis, Paget's disease, etc.) and to prevent metastasis in the bone although the procedures induce osteonecrosis of the jaw through excessive production of reactive oxygen species (ROS). Read More

    Regional Distribution of Longevity Population and Elements in Drinking Water in Jiangjin District, Chongqing City, China.
    Biol Trace Elem Res 2017 Oct 25. Epub 2017 Oct 25.
    Institute of Geographic Sciences and Natural Resources Research, CAS, Beijing, 100101, China.
    In order to determine the spatial variation of longevity population and elements contained in the drinking water of longevity region in Jiangjin and investigate the relationship between the elements in drinking water and longevity, population censuses on township level and 98 drinking water samples from Jiangjin District, Chongqing City in West China were collected and analyzed. Population statistics on township level showed that the number of centenarians per 100,000 inhabitants (OC), centenarity index (CI), and number of centenarians per 10,000 over 65-year-old subjects (UC) present obvious geographic distribution properties, generally Central region > Northern region > Southern region (Kruskal-Wallis test, p < 0.05). Read More

    Toxicity of Copper Oxide (CuO) Nanoparticles on Human Blood Lymphocytes.
    Biol Trace Elem Res 2017 Oct 24. Epub 2017 Oct 24.
    Department of Pharmacology and Toxicology, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, P.O. Box 14155-6153, Tehran, Iran.
    CuO nanoparticles (CuO-NPs) serve several important functions in human life, particularly in the fields of medicine, engineering, and technology. These nanoparticles have been utilized as catalysts, semiconductors, sensors, gaseous and solid ceramic pigments, and magnet rotatable devices. Further use for CuO-NPs has been employed in the pharmaceutical industry especially in the production of anti-microbial fabric treatments or prevention of infections caused by Escherichia coli and methicillin-resistant Staphylococcus aureus. Read More

    Phagocytosis Deficiency of Macrophages in NOD.H-2(h4) Mice Accelerates the Severity of Iodine-Induced Autoimmune Thyroiditis.
    Biol Trace Elem Res 2017 Oct 20. Epub 2017 Oct 20.
    Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, First Affiliated Hospital of China Medical University, No. 155 Nanjing North Street, Shenyang, Liaoning, 110001, China.
    Apoptosis occurs in many autoimmune diseases. Excess iodine induces thyrocyte apoptosis and increases the incidence and prevalence of autoimmune thyroiditis (AIT). However, the sequence of events between the appearance of thyrocyte apoptosis and the occurrence of thyroiditis remains uncharacterized. Read More

    Regulation of Osteoblast Differentiation and Iron Content in MC3T3-E1 Cells by Static Magnetic Field with Different Intensities.
    Biol Trace Elem Res 2017 Oct 19. Epub 2017 Oct 19.
    Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
    Many studies have indicated that static magnetic fields (SMFs) have positive effects on bone tissue, including bone formation and bone healing process. Evaluating the effects of SMFs on bone cell (especially osteoblast) function and exploring the mechanism, which is critical for understanding the possible risks or benefits from SMFs to the balance of bone remodeling. Iron and magnetic fields have the natural relationship, and iron is an essential element for normal bone metabolism. Read More

    Effects of Zinc Oxide Nanoparticles on Performance, Egg Quality, Tissue Zinc Content, Bone Parameters, and Antioxidative Status in Laying Hens.
    Biol Trace Elem Res 2017 Oct 18. Epub 2017 Oct 18.
    Department of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, 14115-336, Iran.
    The objective of this study was to observe the effects of dietary supplementation with zinc oxide nanoparticles (ZnO-NPs) on performance, egg quality, tissue Zn content, bone parameters, superoxide dismutase activity (SOD), and egg malondialdehyde (MDA) content in laying hens. A total of 288 laying hens at 64 weeks of age were randomly assigned to 4 treatments, 6 replicates, with 12 birds each. Experimental diets included the based diet (without Zn supplementation), and basal diet supplemented with 40, 80, and 120 mg Zn/kg from ZnO-NPs. Read More

    Agaricus blazei Murill Polysaccharides Protect Against Cadmium-Induced Oxidative Stress and Inflammatory Damage in Chicken Spleens.
    Biol Trace Elem Res 2017 Oct 14. Epub 2017 Oct 14.
    College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
    Agaricus blazei Murill polysaccharide (ABP) has exhibited antioxidant and immunoregulatory activity. The aim of this study was to investigate the effect of ABP on cadmium (Cd)-induced antioxidant functions and inflammatory damage in chicken spleens. In this study, groups of 7-day-old chickens were fed with normal saline (0. Read More

    Dietary Supplementation with Methylseleninic Acid Inhibits Mammary Tumorigenesis and Metastasis in Male MMTV-PyMT Mice.
    Biol Trace Elem Res 2017 Oct 14. Epub 2017 Oct 14.
    U.S. Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, ND, 58202, USA.
    Male breast cancer, which makes up approximately 1% of all breast cancers, is an aggressive disease with poor prognosis. We investigated the effects of dietary supplementation with selenium in the form of methylseleninic acid [(MSeA) 2.5 mg selenium/kg] on mammary tumorigenesis in male MMTV-PyMT mice. Read More

    Fas- and Mitochondria-Mediated Signaling Pathway Involved in Osteoblast Apoptosis Induced by AlCl3.
    Biol Trace Elem Res 2017 Oct 12. Epub 2017 Oct 12.
    Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, College of Veterinary Medicine, Northeast Agricultural University, No. 59 Mucai Street, Xiangfang District, Harbin, 150030, China.
    Aluminum (Al) is known to induce apoptosis of osteoblasts (OBs). However, the mechanism is not yet established. To investigate the apoptotic mechanism of OBs induced by aluminum trichloride (AlCl3), the primary OBs from the craniums of fetal Wistar rats were exposed to 0 mg/mL (control group, CG), 0. Read More

    The Protective Effect of Selenium on Bovine Mammary Epithelial Cell Injury Caused by Depression of Thioredoxin Reductase.
    Biol Trace Elem Res 2017 Oct 11. Epub 2017 Oct 11.
    College of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, China.
    To elucidate the effect of selenium (Se) on antioxidant function of mammary glands in dairy cows and the underlying mechanism, an experiment was conducted using a single-factor completely randomized design study. Bovine mammary epithelial cells (BMECs) were randomly divided into four groups: control, Se treatment, 2,4-dinitrochlorobenzene (DNCB) inhibition, and Se prevention. Treatment of BMECs with Se was found to significantly reverse decreased cell proliferation and the expression of thioredoxin reductase (TrxR) after DNCB exposure. Read More

    The Effect of Boron on Some Biochemical Parameters in Experimental Diabetic Rats.
    Biol Trace Elem Res 2017 Oct 10. Epub 2017 Oct 10.
    Hakan Çetinsaya Experimental Animal Center, University of Erciyes, Melikgazi, 38039, Kayseri, Turkey.
    In this study, we evaluated the effect of boron (B) as boric acid (BA) on body weight (b.w.); blood glucose; plasma insulin; lipase and paraoxonase (PON1) activities; and serum triglyceride, total cholesterol, high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol, lipid peroxidation (MDA), and total antioxidant capacity (TAC) in streptozotocin (STZ)-induced experimental diabetes in rats. Read More

    Chitosan-Zn Chelate Downregulates TLR4-NF-κB Signal Pathway of Inflammatory Response and Cell Death-Associated Proteins Compared to Inorganic Zinc.
    Biol Trace Elem Res 2017 Oct 10. Epub 2017 Oct 10.
    Key Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China.
    The study was conducted to investigate the effect of chitosan-zinc chelate (CS-Zn) on TLR4-NF-κB signaling pathway and cell death-associated proteins in a weanling pig model. A total of 90 weaned piglets were allotted to three dietary treatments (the dietary treatments were as follows: (1) experimental diet with supplemental ZnSO4 (150 mg Zn/kg diet), (2) experimental diet with supplemental CS-Zn (150 mg Zn/kg diet), and (3) experimental diet with a supplemental mixture of chitosan and ZnSO4 (150 mg/kg Zn; the content of chitosan was equal to CS-Zn, which is according to molar basis)). The feeding trial lasted 30 days. Read More

    The Protective Effect of Selenium on the Chicken Pancreas against Cadmium Toxicity via Alleviating Oxidative Stress and Autophagy.
    Biol Trace Elem Res 2017 Oct 9. Epub 2017 Oct 9.
    College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
    Cadmium (Cd) is a highly toxic heavy metal that can affect human and animal health. Selenium (Se) is an essential microelement that can protect various organs against toxic heavy metals. Although many studies have investigated the adverse effect of Cd in rats and several other animals, little is known regarding the mechanisms of Cd-induced autophagy in the chicken pancreas and the antagonistic effect of Se on Cd. Read More

    Comparative In Vitro Toxicity Evaluation of Heavy Metals (Lead, Cadmium, Arsenic, and Methylmercury) on HT-22 Hippocampal Cell Line.
    Biol Trace Elem Res 2017 Oct 9. Epub 2017 Oct 9.
    Environmental Engineering Laboratory, Departament d'Enginyeria Quimica, Universitat Rovira i Virgili, Av. Països Catalans 26, 43007, Tarragona, Spain.
    Heavy metals are considered some of the most toxic environmental pollutants. Exposure to heavy metals including lead (Pb), cadmium (Cd), arsenic (As), and methyl mercury (MeHg) has long been known to cause damage to human health. Many recent studies have supported the hippocampus as the major target for these four metals for inflicting cognitive dysfunction. Read More

    Characterization, Cytotoxicity, and Genotoxicity of TiO2 and Folate-Coupled Chitosan Nanoparticles Loading Polyprenol-Based Nanoemulsion.
    Biol Trace Elem Res 2017 Oct 9. Epub 2017 Oct 9.
    Institute of Chemical Industry of Forest Products, CAF, Nanjing, Jiangsu Province, 210042, China.
    The structure and bioactivity of Ginkgo biloba leaves polyprenol (GBP) are similar to that of dolichol which widely exists in human and mammalian organs. GBP possesses potential pharmacological activities against cancer. This study involved oil-in-water type nanoemulsion (NE) loading GBP was prepared by dissolving polyprenol in nanoemulsion of sodium tripolyphosphate (TPP)/TiO2 solution, Triton X-100, and 1-octanol by inversed-phase emulsification (EIP) and ultrasonic emulsification (UE) method. Read More

    Blood Cadmium Concentrations in Women with Ectopic Pregnancy.
    Biol Trace Elem Res 2017 Oct 8. Epub 2017 Oct 8.
    Laboratory of Atomic Absorption Spectrometry, Scientific and Technological Research Center, Inonu University, Malatya, Turkey.
    The purpose of this study is to investigate the relationship between the blood level of cadmium and the occurrence of ectopic pregnancy. Forty-one (41) case patients with ectopic pregnancy and 41 uncomplicated intrauterine pregnant patients as controls were recruited. The concentrations of cadmium (Cd) were measured from blood samples using atomic absorption spectrometry. Read More

    Effects of Fluoride on SOD and CAT in Testis and Epididymis of Mice.
    Biol Trace Elem Res 2017 Oct 8. Epub 2017 Oct 8.
    College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, China.
    Oxidative damage has been implicated to be one of main mechanisms by which fluoride (F) induces toxic effects. Previous studies reported that F destroyed the epididymal structure of mouse and rabbit. Epididymis is the important place for sperm maturation. Read More

    Evaluation of Potassium Dichromate (K2Cr2O7)-Induced Liver Oxidative Stress and Ameliorative Effect of Picrorhiza kurroa Extract in Wistar Albino Rats.
    Biol Trace Elem Res 2017 Oct 9. Epub 2017 Oct 9.
    Applied Nutrition Division, Defence Food Research Laboratory, DRDO, Siddhartha Nagar, Mysore, 570011, India.
    The aim of the study was to assess the protective effect of Picrorhiza kurroa hydroalcoholic extract (PCK), a glycoside-rich extract, against potassium dichromate (PDC)-induced liver oxidative stress in Wistar albino rats. Thirty-six male Wistar rats were divided into six groups: the control group (which received distilled water), the SIL group (which received 60 mg/kg silymarin), the PDC group (which received 30 mg/kg K2Cr2O7), and the treatment groups (which received 25, 50, 100 mg/kg PCK). Administration of PDC resulted in increased levels of liver enzymes such as alanine transaminase (ALT), aspartate transaminase (AST), and alkaline phosphatase (ALP); up-regulated peroxidation biomarkers, i. Read More

    Lithium Treatment Aggregates the Adverse Effects on Erythrocytes Subjected to Arsenic Exposure.
    Biol Trace Elem Res 2017 Oct 7. Epub 2017 Oct 7.
    Department of Biophysics, Panjab University Chandigarh, Chandigarh, 160014, India.
    The present study was designed to investigate the effects of lithium treatment on red blood cells which were given arsenic exposure. Long-term lithium therapy is being extensively used for the treatment of bipolar disorders. Arsenic is a group I carcinogen and a major toxic pollutant in drinking water that affects millions of people worldwide. Read More

    Biogenic and Risk Elements in Wines from the Slovak Market with the Estimation of Consumer Exposure.
    Biol Trace Elem Res 2017 Oct 7. Epub 2017 Oct 7.
    Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054, Krakow, Poland.
    Wine consumption delivers macroelements and microelements necessary for the proper metabolism. On the other hand, wine can be an important source of toxic metals. The aim of this study was to estimate the concentrations of Ca, Cd, Cu, Fe, Hg, Mg, Ni, Pb, and Zn in the Slovak and non-Slovak wines. Read More

    Scarce Occurrence of Calcification in Human Sinoatrial Nodal Arteries in Old Age.
    Biol Trace Elem Res 2017 Oct 7. Epub 2017 Oct 7.
    Department of Anatomy, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.
    To elucidate age-related changes of the sinoatrial (sinuatrial) nodal (SAN) artery, the authors investigated age-related changes of elements in the SAN artery by direct chemical analysis. In addition, the effects of different arterial origins, arterial sizes, and genders on element accumulation were investigated in the SAN artery. Fifty-nine formalin-fixed adult Thai hearts were dissected, and the following three types of the SAN artery were found: The first type was a single SAN artery arising from the right coronary artery (RCA). Read More

    Associations Between Selenium Content in Hair and Kashin-Beck Disease/Keshan Disease in Children in Northwestern China: a Prospective Cohort Study.
    Biol Trace Elem Res 2017 Oct 6. Epub 2017 Oct 6.
    School of Public Health, Health Science Center, Key Laboratory of Trace Elements and Endemic Diseases, National Health and Family Planning Commission of People's Republic of China, Xi'an Jiaotong University, No.76 Yan Ta West Road, Xi'an, Shannxi, 710061, People's Republic of China.
    The objective of this study was to investigate the relationship between selenium content in hair and the incidence of Kashin-Beck disease (KBD) and Keshan disease (KD) in China. A prospective cohort study was conducted among children aged 5-12 years with different levels of low-selenium (group 1, Se ≤ 110 ng/g; group 2, 110 < Se ≤ 150 ng/g; and group 3, 150 < Se ≤ 200 ng/g) or selenium-supplemented (group 4, Se > 200 ng/g) exposure. A person-years approach was used to calculate the incidence and rate of positive clinical signs. Read More

    Selenoprotein K Mediates the Proliferation, Migration, and Invasion of Human Choriocarcinoma Cells by Negatively Regulating Human Chorionic Gonadotropin Expression via ERK, p38 MAPK, and Akt Signaling Pathway.
    Biol Trace Elem Res 2017 Oct 6. Epub 2017 Oct 6.
    Department of Biochemistry and Molecular Biology, Basic Medical Science College, Harbin Medical University, 157 Baojian Road, Harbin, 150081, China.
    Selenoprotein K (SelK), a member of selenoprotein family, is identified as a single endoplasmic reticulum (ER) transmembrane protein. Although over-expression of SelK inhibits adherence and migration of human gastric cancer BGC-823 cells, the effects of SelK in human choriocarcinoma (CCA) are not well understood. In this study, the expression levels of SelK in three CCA cell lines, BeWo, JEG-3, and JAR, were examined. Read More

    MRP2 and the Transport Kinetics of Cysteine Conjugates of Inorganic Mercury.
    Biol Trace Elem Res 2017 Oct 4. Epub 2017 Oct 4.
    Department of Biomedical Sciences, Mercer University School of Medicine, 1501 College St., Macon, GA, 31207, USA.
    Human exposure to mercuric species occurs regularly throughout the world. Mercuric ions may accumulate in target cells and subsequently lead to cellular intoxication and death. Therefore, it is important to have a thorough understanding of how transportable species of mercury are handled by specific membrane transporters. Read More

    Effect of Selenium on Ion Profiles and Antioxidant Defense in Mice Livers.
    Biol Trace Elem Res 2017 Oct 4. Epub 2017 Oct 4.
    Zhongkai University of Agriculture and Engineering, Guangzhou, 501225, China.
    Se entering the mammalian body from diverse sources shows different liver accumulation patterns. However, the effects of Se from diverse sources on the body's I on spectrum and the relationship between the changes in the ion spectrum and antioxidant function are not clear. In this study, 80 3-week-old female mice were randomly divided into four groups: a control group, sodium selenite group, yeast Se group, and seaweed Se group. Read More

    Comparison Study of Bone Defect Healing Effect of Raw and Processed Pyritum in Rats.
    Biol Trace Elem Res 2017 Oct 4. Epub 2017 Oct 4.
    College of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Nanjing, 210023, Jiangsu, People's Republic of China.
    To evaluate and compare the effect of raw and processed pyritum on tibial defect healing, 32 male Sprague Dawley rats were randomly divided into four groups. After tibial defect, animals were produced and grouped: sham and control group were orally administrated with distilled water (1 mL/100 g), while treatment groups were given aqueous extracts of raw and processed pyritum (1.5 g/kg) for successive 42 days. Read More

    Nigella sativa Oil and Chromium Picolinate Ameliorate Fructose-Induced Hyperinsulinemia by Enhancing Insulin Signaling and Suppressing Insulin-Degrading Enzyme in Male Rats.
    Biol Trace Elem Res 2017 Oct 4. Epub 2017 Oct 4.
    Department of Biochemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Sharkia, 44519, Egypt.
    In vivo and in vitro studies suggested that chromium enhances insulin sensitivity by promoting insulin receptor signaling. However, its effect on insulin clearance has not been yet identified. Nigella sativa, a widely used spice, possesses an antidiabetic activity. Read More

    The Effect of Chitosan on the Erythrocyte Antioxidant Potential of Lead Toxicity-Induced Rats.
    Biol Trace Elem Res 2017 Oct 2. Epub 2017 Oct 2.
    Biochemistry Department, Faculty of Veterinary Medicine, University of Yuzuncu Yil, Yuzuncu Yil, 65080, Van, Turkey.
    In the present study, the effects of chitosan on erythrocyte malondialdehyde (MDA) and glutathione (GSH) levels and glutathione peroxidase (GSH-Px), glutathione reductase (GR), and glucose-6-phosphate dehydrogenase (G6PDH) enzyme activities in lead toxicity-induced rats were investigated. Twenty-eight male Wistar albino rats were divided into four groups of control (C), lead group (Pb group), lead + chitosan group (Pb + CS group), and chitosan group (CS group). Lead groups were administered 50 mg/kg lead acetate intraperitoneally (ip) for 5 days and chitosan groups were administered 200 mg/kg chitosan for 28 days via gavage. Read More

    Heterogeneity of Multimedia Exposures to Neurotoxic Elements (Al, As, Cd, Pb, Mn, and Hg) in Breastfed Infants from Porto Velho, Brazil.
    Biol Trace Elem Res 2017 Oct 1. Epub 2017 Oct 1.
    Environmental Biogeochemistry Laboratory WCP, Federal University of Rondônia, Porto Velho, RO, 76815-800, Brazil.
    Infant exposure to neurotoxic elements is a public health issue that needs monitoring with regard to breast milk composition. We studied six neurotoxic elements in breast milk samples at different stages of lactation in mothers from Porto Velho, Brazil. We used a flow-injection mercury system (FIMS) to determine total Hg concentrations and an inductively coupled plasma optical emission spectrometer (ICP-OES) to determine the concentrations of Al, As, Cd, Pb, and Mn in 106 donors of a human milk bank. Read More

    Protective Role of Selenium in Immune-Relevant Cytokine and Immunoglobulin Production by Piglet Splenic Lymphocytes Exposed to Deoxynivalenol.
    Biol Trace Elem Res 2017 Sep 26. Epub 2017 Sep 26.
    College of Veterinary Medicine, Sichuan Province Key Laboratory of Animal Disease and Human Health, Key Laboratory of Environmental Hazard and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, 611130, China.
    Deoxynivalenol (DON) is a mycotoxin that causes immunosuppression, especially in swine. Selenium (Se) is essential for proper functioning of the immune system in animals. However, little is known about the effects of DON and Se on cytokine or immunoglobulin production in piglets. Read More

    Zinc Status in Beta Thalassemia Major Patients.
    Biol Trace Elem Res 2017 Sep 23. Epub 2017 Sep 23.
    Department of Pediatrics, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
    Beta thalassemia is a common monogenic hereditary hemoglobinopathy which is associated with compound complications. Zinc deficiency, which is commonly observed in thalassemia patients, is also associated with multiple health complications. The objective of this study was to determine the zinc status and its effect on the growth and immune functions of young beta thalassemia major patients. Read More

    Cytoprotective Effects of the Red Marine Alga Chondrus canaliculatus Against Maneb-Induced Hematotoxicity and Bone Oxidative Damages in Adult Rats.
    Biol Trace Elem Res 2017 Sep 22. Epub 2017 Sep 22.
    Unit of Functional Genomics and Plant Physiology, Higher Institute of Biotechnology of Sfax, University of Sfax, 3000, Sfax, Tunisia.
    The current study aimed at evaluating the ability of a mineral and antioxidant-rich extract from Chondrus canaliculatus to improve maneb (MB)-induced toxicity in adult rat. The animals were divided into four groups: group 1 used as a control group, group 2 received MB, group 3 received MB + C. canaliculatus extract, and group 4 received only the algal extract. Read More

    Trace Metal Levels in Rainbow Trout (Oncorhynchus mykiss) Cultured in Net Cages in a Reservoir and Evaluation of Human Health Risks from Consumption.
    Biol Trace Elem Res 2017 Sep 19. Epub 2017 Sep 19.
    Aquaculture Research Institute, Elazığ, Turkey.
    Although fish consumption has positive health effects, metals accumulated in fish can cause human health risks. In this study, the levels of ten metals in rainbow trout (Oncorhynchus mykiss) farmed in the Keban Dam Reservoir, which has the biggest rainbow trout production capacity in Turkey, were determined and compared with the maximum permissible levels (MPLs). Also, human health risks associated with rainbow trout consumption were assessed. Read More

    Nutrients Other than Selenium Are Important for Promoting Children's Health in Kashin-Beck Disease Areas.
    Biol Trace Elem Res 2017 Sep 18. Epub 2017 Sep 18.
    School of Public Health, Health Science Center, Xi'an Jiaotong University, Key Laboratory of Trace Elements and Endemic Diseases, National Health and Family Planning Commission, No.76 Yanta West Road, Xi'an, 710061, People's Republic of China.
    Overall nutritional status has been proved associated with people's health. The overall nutritional status of children in Kashin-Beck disease (KBD) areas has been overlooked for decades. Therefore, it is worth investigating in the current generation to gather evidence and make suggestions for improvement. Read More

    Manganese-Induced Neurotoxicity and Alterations in Gene Expression in Human Neuroblastoma SH-SY5Y Cells.
    Biol Trace Elem Res 2017 Sep 15. Epub 2017 Sep 15.
    Environmental Impact and Sustainability Division, CSIR-National Environmental Engineering Research Institute (NEERI), Nagpur, India.
    Manganese (Mn) is an essential trace element required for many physiological functions including proper biochemical and cellular functioning of the central nervous system (CNS). However, exposure to excess level of Mn through occupational settings or from environmental sources has been associated with neurotoxicity. The cellular and molecular mechanism of Mn-induced neurotoxicity remains unclear. Read More

    A Spectroscopic Study of Interaction of Auricyanide with n-Acetylcysteine.
    Biol Trace Elem Res 2017 Sep 14. Epub 2017 Sep 14.
    Department of Chemistry, Illinois State University, Normal, IL, 61790-4160, USA.
    Interaction of auricyanide, an important metabolite of anti-arthritic gold-based drug auranofin, was studied in vitro with a pharmacologically active ligand n-acetylcysteine with a view to understand reactivity of gold in vivo. Formation of reduction product aurocyanide occurred through mono- and di-n-acetylcysteine-substituted intermediates. The product and intermediates were identified and monitored spectrophotometrically and by electrospray ionization mass spectrometry. Read More

    1 OF 126