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    6336 results match your criteria Biological trace element research[Journal]

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    Effects of Dietary Zinc Oxide Nanoparticles on Growth, Diarrhea, Mineral Deposition, Intestinal Morphology, and Barrier of Weaned Piglets.
    Biol Trace Elem Res 2018 Feb 21. Epub 2018 Feb 21.
    College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
    This study was conducted to investigate effects of dietary zinc oxide nanoparticles (nano-ZnOs) on growth, diarrhea rate, mineral deposition (Zn, Fe, and Mn), intestinal morphology, and barrier of weaned piglets. A total of 384 weaned piglets (Duroc × Landrace × Yorkshire) in 4 groups were fed a basal diet supplemented with 0, 400, and 800 mg/kg nano-ZnOs or 3000 mg/kg ZnO for 14 days. Compared with the control group, 800 mg/kg nano-ZnOs and 3000 mg/kg ZnO significantly increased average daily gain and decreased diarrhea rate of weaned piglets. Read More

    Selenium-Enriched Saccharomyces cerevisiae Reduces the Progression of Colorectal Cancer.
    Biol Trace Elem Res 2018 Feb 21. Epub 2018 Feb 21.
    Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
    Colorectal cancer is one of the most common causes of mortality in the world while malnutrition is responsible for one third of the problem. Selenium has been recommended for prevention of colorectal cancer. The present study was conducted to investigate the effect of selenium-enriched Saccharomyces cerevisiae in reducing colorectal cancer progression in rats. Read More

    Influences of Copper/Zinc-Loaded Montmorillonite on Growth Performance, Mineral Retention, Intestinal Morphology, Mucosa Antioxidant Capacity, and Cytokine Contents in Weaned Piglets.
    Biol Trace Elem Res 2018 Feb 21. Epub 2018 Feb 21.
    Animal Science College, Key Laboratory of Molecular Animal Nutrition, Ministry of Education; Key Laboratory of Animal Nutrition and Feed in East China, Ministry of Agriculture, Zhejiang University, Hangzhou, 310058, China.
    The effects of copper/zinc-loaded montmorillonite (Cu/Zn-Mt) on growth performance, mineral retention, intestinal morphology, mucosa antioxidant capacity, and cytokine contents in weaned piglets were investigated in the present study. One hundred eight piglets weaned at 21 ± 1 days of age (Duroc × Landrace× Yorkshire; average initial weight of 6.36 kg) were allotted to three treatments for 2 weeks. Read More

    Fluoride Alters Serum Elemental (Calcium, Magnesium, Copper, and Zinc) Homeostasis Along with Erythrocyte Carbonic Anhydrase Activity in Fluorosis Endemic Villages and Restores on Supply of Safe Drinking Water in School-Going Children of Nalgonda District, India.
    Biol Trace Elem Res 2018 Feb 17. Epub 2018 Feb 17.
    Department of Statistics, National Institute of Nutrition, ICMR, Hyderabad, India.
    The present study aimed to determine the serum trace elements (copper (Cu), zinc (Zn), calcium (Ca), magnesium (Mg)) along with erythrocyte carbonic anhydrase (CA) activity and effect of intervention with safe drinking water for 5 years in the school children of fluorosis endemic area. For this purpose, three categories of villages were selected based on drinking water fluoride (F): Category I (control, F = 1.68 mg/L), category II (affected F = 3. Read More

    Effects of Silver Nanoparticles on Hematological Parameters and Hepatorenal Functions in Laying Japanese Quails.
    Biol Trace Elem Res 2018 Feb 15. Epub 2018 Feb 15.
    Department of Immunology & Hematology, Kurdistan University of Medical Sciences, Sanandaj, 6618634683, Iran.
    Silver nanoparticles (AgNPs) have recently emerged as a powerful agents for disinfection in the poultry industry. AgNPs are capable of epithelial barriers passing from the route of exposure to the vital organs and cells. This study evaluated the effects of AgNPs on organs weights, blood biochemical, hematological, and coagulation parameters, antioxidant enzyme activities, and histopathological changes and silver concentrations of liver and kidney tissues in laying Japanese quails after exposure to the nanoparticles. Read More

    Accumulation Patterns of Sub-chronic Aluminum Toxicity Model After Gastrointestinal Administration in Rats.
    Biol Trace Elem Res 2018 Feb 13. Epub 2018 Feb 13.
    Institute of Toxicology of Federal Medico-Biological Agency, St. Petersburg, Russia.
    Although aluminum chronic neurotoxicity is well documented, there are no well-established experimental protocols of Al exposure. In the current study, toxic effects of sub-chronic Al exposure have been evaluated in outbreed male rats (gastrointestinal administration). Forty animals were used: 10 were administered with AlClwater solution (2 mg/kg Al per day) for 1 month, 10 received the same concentration of AlClfor 3 month, and 20 (10 per observation period) saline as control. Read More

    Preliminary Study of Mechanisms of Fluoride-Induced Suppression of Nitric Oxide Synthesis in Human Umbilical Vein Endothelial Cells.
    Biol Trace Elem Res 2018 Feb 12. Epub 2018 Feb 12.
    Department of Rheumatology and Immunology, the First Hospital, Jilin University, 71# Xinmin Street, Changchun, 130021, China.
    This study was aimed to determine if excessive exposure to fluoride could suppress the synthesis of nitric oxide (NO) and to detail the mechanisms involved. With the exception of the control group, human umbilical vein endothelial cells (HUVECs) were treated with sodium fluoride (NaF) (1.2 μg/mL) for 24 h, with or without a 2-h pretreatment with 100 nM insulin-like growth factor 1 (IGF-1, a PI3K/AKT agonist), or 10 μM histamine (HIS, a eNOS agonist). Read More

    Toxicological Effects of Mercury Chloride on Laying Performance, Egg Quality, Serum Biochemistry, and Histopathology of Liver and Kidney in Laying Hens.
    Biol Trace Elem Res 2018 Feb 9. Epub 2018 Feb 9.
    College of Animal Science, Zhejiang University, Hangzhou, 310058, China.
    The objective of this study was to determine the effects of mercury chloride (HgCl) on laying performance, egg quality, hepatic and renal histopathology, and serum biochemical profiles in laying hens. A total of 768 Hy-line brown laying hens aged 40 weeks were randomly allocated to four groups (8 pens per group and 24 hens per pen). The concentrations of mercury (Hg) in four groups were 0. Read More

    Probiotics as a Complementary Therapy in the Model of Cadmium Chloride Toxicity: Crosstalk of β-Catenin, BDNF, and StAR Signaling Pathways.
    Biol Trace Elem Res 2018 Feb 9. Epub 2018 Feb 9.
    Molecular Biology, Therapeutic Chemistry Department, National Research Centre, Cairo, Egypt.
    Cadmium chloride (CdCl) is a ubiquitous environmental toxicant that causes a variety of disturbances in biological systems, including brain dysfunction and testicular tissue degeneration. On the other hand, it is supposed that beneficial properties of probiotic bacteria (Lactobacillus and Acidobacillus) are related to their capacity to adhere or bind different targets, thus leading to improved intestinal microbial balance and other benefits to the host. Bearing aforementioned in mind, the present study was undertaken to investigate the protective effect of probiotic supplementation against cadmium chloride-induced brain and testis toxicity in mice model. Read More

    Effect of In Ovo Zinc Injection on the Embryonic Development and Epigenetics-Related Indices of Zinc-Deprived Broiler Breeder Eggs.
    Biol Trace Elem Res 2018 Feb 9. Epub 2018 Feb 9.
    College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
    The role of in ovo zinc (Zn) injection in improving the embryonic development in eggs from Zn-deficient hens, via epigenetic and antioxidant mechanisms, was examined. A completely randomized design involving a 1 (the non-injected control) + 1 (the injected control with sterilized water) + 2 (Zn source) × 2 (Zn level) factorial arrangement of treatments was used. The two injected Zn sources were inorganic Zn sulfate and organic Zn-lysine chelate with a moderate chelation strength, and the two injected Zn levels were 50 and 100 μg Zn/egg. Read More

    Chronic Exposure to Fluoride During Gestation and Lactation Increases Mandibular Bone Volume of Suckling Rats.
    Biol Trace Elem Res 2018 Feb 6. Epub 2018 Feb 6.
    Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra "A" de Química Biológica. Pabellón Argentina, Ciudad Universitaria, 5000, Córdoba, Argentina.
    We aimed to investigate the effect of maternal exposure to NaF on mandibular bone microarchitecture and phosphocalcic plasma parameters of the offspring. For this purpose, 10-, 15-, and 21-day-old pups (n = 6-8 per group) from two groups of mothers, control and NaF 50mg/L treated dams, were used. Plasma calcium (Ca) and phosphorus (P) levels and alkaline phosphatase activity (ALP) were measured. Read More

    Effects of Copper and Zinc Supplementation on Weight Gain and Hematological Parameters in Pre-weaning Calves.
    Biol Trace Elem Res 2018 Feb 5. Epub 2018 Feb 5.
    Laboratorio de Nutrición Mineral, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, 60 y 118, 1900, La Plata, Argentina.
    Cow-calf operations may be affected by trace mineral deficiencies, particularly copper (Cu) and zinc (Zn) deficiency, which may decrease the calf daily weight gain and alter hematological parameters. We evaluated the effect of Cu and Zn supplementation on pre-weaning calves (n = 40; 92 ± 6 kg initial body weight) from the Salado River basin, Buenos Aires, Argentina. Calves were divided into four groups (n = 10 each) and subcutaneously administered 0. Read More

    Comparing the Effects of Chitosan Scaffolds Containing Various Divalent Metal Phosphates on Osteogenic Differentiation of Stem Cells from Human Exfoliated Deciduous Teeth.
    Biol Trace Elem Res 2018 Feb 4. Epub 2018 Feb 4.
    Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, 1 Sec. 3, Chung-Hsiao E. Rd, Taipei, 10608, Taiwan.
    Inducing the differentiation of stem cells from human exfoliated deciduous teeth (SHEDs) proceeds with low efficiency, which greatly limits clinical applications. Divalent metal elements play an important role in osteoinductivity for bone remodeling because they can simulate bone formation and decrease bone resorption. The purpose of this study was to investigate the effect of some divalent metal phosphates on osteogenic differentiation from human exfoliated deciduous teeth. Read More

    Protective Effects of Quercetin Against Cadmium Chloride-Induced Oxidative Injury in Goat Sperm and Zygotes.
    Biol Trace Elem Res 2018 Feb 4. Epub 2018 Feb 4.
    Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Taicheng Road, Yangling, Xianyang, Shaanxi, 712100, China.
    Quercetin, a plant-derived flavonoid, is frequently used as an antioxidant for efficient anti-oxidative capacity. However, whether quercetin has protective effects on goat sperm and preimplantation embryos against Cd-induced oxidative injury is still unclear. So, we researched the influence of quercetin on goat sperm and zygotes respectively under the oxidative stress induced by Cd. Read More

    Bone Strength in Growing Rats Treated with Fluoride: a Multi-dose Histomorphometric, Biomechanical and Densitometric Study.
    Biol Trace Elem Res 2018 Feb 2. Epub 2018 Feb 2.
    Bone Biology Laboratory, School of Medicine, Rosario National University, Rosario, S2002KTR, Santa Fe, Argentina.
    Bone deformation and fragility are common signs of skeletal fluorosis. Disorganisation of bone tissue and presence of inflammatory foci were observed after fluoride (F) administration. Most information about Feffects on bone has been obtained in adult individuals. Read More

    Selenium (NaSeO) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
    Biol Trace Elem Res 2018 Jan 31. Epub 2018 Jan 31.
    Department of Animal Genetics, Breeding and Reproduction, College of Animal Science and Technology, Northeast Agricultural University, Harbin, People's Republic of China.
    Sertoli cells were isolated from newborn calves and cultured in a medium supplemented with 0, 0.25, 0.50, 0. Read More

    Dietary Supplementation with Chromium Picolinate Influences Serum Glucose and Immune Response of Brown-Egg Laying Hens.
    Biol Trace Elem Res 2018 Jan 29. Epub 2018 Jan 29.
    Mineral Nutrition Research Division, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, 100193, People's Republic of China.
    To investigate the effect of chromium picolinate (CrPic) on egg production performance, egg quality, blood indices, and immune function of laying hens, 270 23-week-old Beijing Red brown-egg laying hens were randomly assigned to one of three treatments with six replicates of 15 birds per replicate for each treatment in a completely randomized design. Laying hens were fed a Cr-unsupplemented corn-soybean meal basal diet (control, containing 0.45 mg Cr/kg by analysis) or the basal diet supplemented with 0. Read More

    pH-Dependent Effects of L-Cysteine on Mercury Dissolution of α-HgS and β-HgS.
    Biol Trace Elem Res 2018 Jan 29. Epub 2018 Jan 29.
    Northwest Institute of Plateau Biology, Qinghai Provincial Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Chinese Academy of Sciences, Xin-ning Road 23, Xi-ning, Qinghai, China.
    Mercury sulfide is an insoluble inorganic mercury compound, and it is the main chemical form in traditional oral mercury-containing medicines. Hghas a high affinity for thiols, and small molecule thiols in the gastrointestinal tract may promote mercury dissolution of mercury sulfide by binding to Hg. L-cysteine is the only amino acid that possesses a reducing sulfhydryl group (-SH), out of the 20 amino acids. Read More

    Zinc Supplementation Does Not Affect Glucagon Response to Intravenous Glucose and Insulin Infusion in Patients with Well-Controlled Type 2 Diabetes.
    Biol Trace Elem Res 2018 Jan 26. Epub 2018 Jan 26.
    Department of Nutrition, Faculty of Medicine, University of Chile, Independencia 1027, Santiago, Chile.
    Glucagon dysregulation is an essential component in the pathophysiology of type 2 diabetes. Studies in vitro and in animal models have shown that zinc co-secreted with insulin suppresses glucagon secretion. Zinc supplementation improves blood glucose control in patients with type 2 diabetes, although there is little information about how zinc supplementation may affect glucagon secretion. Read More

    Breast Milk Iodine Concentration Rather than Maternal Urinary Iodine Is a Reliable Indicator for Monitoring Iodine Status of Breastfed Neonates.
    Biol Trace Elem Res 2018 Jan 25. Epub 2018 Jan 25.
    Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, P.O. Box: 19395-4763, Tehran, Iran.
    There is no scientific consensus on whether breast milk iodine concentration (BMIC) accurately reflects iodine status in lactating mothers and breastfed infants. This study aimed to compare BMIC and maternal urinary iodine concentration (UIC) as indicators of iodine status in breastfed neonates. In this cross-sectional study, 147 lactating mothers and their neonates (3-5 days postpartum) were randomly selected from health care centers. Read More

    Antioxidant and Cytoprotective Activity of Oxydiacetate Complexes of Cobalt(II) and Nickel(II) with 1,10-Phenantroline and 2,2'-Bipyridine.
    Biol Trace Elem Res 2018 Jan 25. Epub 2018 Jan 25.
    Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308, Gdańsk, Poland.
    The antioxidant properties of oxydiacetate complexes of cobalt(II) and nickel(II) with 1,10-phenantroline and 2,2'-bipyridine have been investigated towards the superoxide radical using the nitro blue tetrazolium chloride (NBT) test and the cyclic voltammetry (CV). Moreover, the biological activity of the complexes under study has been investigated in the Human Dermal Fibroblasts adult (HDFa) cell line. In the first step, the cytotoxic and the antiproliferative activities of the complexes were examined. Read More

    Cadmium Profiles in Dental Calculus: a Cross-Sectional Population-Based Study in Hunan Province of China.
    Biol Trace Elem Res 2018 Jan 24. Epub 2018 Jan 24.
    Hanwoo DNA Solutions Co., Ltd, Changsha, China.
    We aimed to investigate whether the cadmium concentrations differ in human dental calculus obtained from the residents with no smoking living in the contaminated area and those with no smoking living in noncontaminated area. In total, there were 260 samples of dental calculus from the adults (n = 50) with no smoking living in contaminated area, the adults (n = 60) with no smoking living in mountainous area, and the adults (n = 150) with no smoking living in low altitude area in Hunan province of China. All samples were analyzed by inductively coupled plasma mass spectrometry (ICP-MS) for cadmium levels. Read More

    Correction to: Biomonitoring of Trace Metals in the Keban Dam Reservoir (Turkey) Using Mussels (Unio elongatulus eucirrus) and Crayfish (Astacus leptodactylus).
    Biol Trace Elem Res 2018 Jan 22. Epub 2018 Jan 22.
    Aquaculture Research Institute, Elazığ, Turkey.
    The original version of this article contained mistakes: the units mg/kgand μg/kgfound on tables 1, 2, 4, 5 and 6 should be mg kgand μg kg, respectively. Read More

    Mercuric Chloride Induced Ovarian Oxidative Stress by Suppressing Nrf2-Keap1 Signal Pathway and its Downstream Genes in Laying Hens.
    Biol Trace Elem Res 2018 Jan 18. Epub 2018 Jan 18.
    Key Laboratory of Animal Feed and Nutrition of Zhejiang Province, Feed Science Institute, College of Animal Science, Zhejiang University, Hangzhou, 310058, China.
    The present study evaluated the effects of mercury chloride (HgCl) on follicular atresia rate, sex hormone secretion, and ovarian oxidative stress in laying hens. Antioxidant enzyme genes and the nuclear factor erythroid 2-related factor 2 (Nrf2)-Kelch-like ECH-associated protein 1 (Keap1) signal pathway were further studied to uncover the molecular mechanism. A total of 768 40-week-old Hy-Line Brown laying hens were randomly allocated to four treatments with eight pens per treatment and 24 hens of each pen. Read More

    Environment-Friendly Synthesis of Trace Element Zn, Sr, and F Codoping Hydroxyapatite with Non-cytotoxicity and Improved Osteoblast Proliferation and Differentiation.
    Biol Trace Elem Res 2018 Jan 18. Epub 2018 Jan 18.
    Key Laboratory of Inorganic Coating Materials CAS, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China.
    Hydroxyapatite (HAp, Ca[PO][OH]) doped with numerous trace elements possesses sensational biochemical effects in natural bones. To study the biochemical function of Zn, Sr, and F elements, a series of neoteric HAp biomaterials with Zn, Sr, and F concentrations close to natural bones are firstly synthesized by one-pot hydrothermal method. These materials are characterized through powder X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscope (SEM). Read More

    Dietary Chromium Picolinate Supplementation Affects Growth, Whole-Body Composition, and Gene Expression Related to Glucose Metabolism and Lipogenesis in Juvenile Blunt Snout Bream, Megalobrama amblycephala.
    Biol Trace Elem Res 2018 Jan 18. Epub 2018 Jan 18.
    Key Laboratory for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Freshwater Fisheries Research Center (FFRC), Chinese Academy of Fishery Sciences (CAFS), Wuxi, 214081, People's Republic of China.
    An 11-week feeding trial was carried out to investigate the effects of supplemented chromium picolinate (Cr-Pic) on the growth, whole-body composition, and relative mRNA expression related to lipogenesis and glucose metabolism in juvenile blunt snout bream. Seven isonitrogenous and isoenergetic diets with graded Cr supplementation levels were fed to triplicate groups. The final weight (FW), feed conversion ratio (FCR), and specific growth rate (SGR) were improved with increasing dietary Cr supplementation levels up to 0. Read More

    The Content of Mercury in Herbal Dietary Supplements.
    Biol Trace Elem Res 2018 Jan 17. Epub 2018 Jan 17.
    Department of Toxicology and Bioanalysis School of Pharmacy with the Division of Laboratory Medicine, Medical University of Silesia, 4 Jagiellonska Str, 41-200, Sosnowiec, Poland.
    The dietary supplement market in Poland has been growing rapidly, and the number of registered products and their consumption increases steadily. Among the most popular and the easiest to get are herbal supplements, available in any supermarket. The aim of this paper was to investigate the mercury content in the herbal supplements. Read More

    Comparative Proteomics of Chromium-Transformed Beas-2B Cells by 2D-DIGE and MALDI-TOF/TOF MS.
    Biol Trace Elem Res 2018 Jan 16. Epub 2018 Jan 16.
    Nanjing Military Region Stomatological Center, No. 359 Hospital, the People's Liberation Army, Zhenjiang, China.
    Chromium (Cr) is a highly toxic, common heavy metal used in industrial production. There are two types of Cr in nature: hexavalent chromium (Cr(VI)) and chromium trichloride (Cr(III)). Cr(III) is involved in the metabolism of sugars and lipids, whereas Cr(VI) is absorbed through the respiratory tract and skin and generates free radicals that result in secondary toxicity. Read More

    Low, but Not High, Doses of Copper Sulfate Impair Synaptic Plasticity in the Hippocampal CA1 Region In Vivo.
    Biol Trace Elem Res 2018 Jan 15. Epub 2018 Jan 15.
    Department of Physiology, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.
    Previous studies have shown the inhibitory effect of the in vitro application of copper sulfate on hippocampal long-term potentiation. While in vivo administration of copper did not affect spatial learning and memory. To find possible answers to this controversial issue, we evaluate the effect of different doses of copper sulfate on in vivo long-term potentiation, synaptic transmission, and paired-pulse behavior of CA1 pyramidal cells. Read More

    Methylmercury Intoxication Promotes Metallothionein Response and Cell Damage in Salivary Glands of Rats.
    Biol Trace Elem Res 2018 Jan 14. Epub 2018 Jan 14.
    Laboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Para, Street Augusto Correa N. 01, Guamá, Belém, Para, 66075-900, Brazil.
    Environmental and occupational mercury exposure is considered a major public health issue. Despite being well known that MeHg exposure causes adverse effects in several physiologic functions, MeHg effects on salivary glands still not completely elucidated. Here, we investigated the cellular MeHg-induced damage in the three major salivary glands (parotid, submandibular, and sublingual) of adult rats after chronic, systemic and low doses of MeHg exposure. Read More

    Metal Concentrations in Tissues of Gadwall and Common Teal from Miankaleh and Gomishan International Wetlands, Iran.
    Biol Trace Elem Res 2018 Jan 13. Epub 2018 Jan 13.
    Illinois Natural History Survey, University of Illinois at Urbana-Champaign, Champaign, USA.
    Miankaleh and Gomishan International Wetlands are important wintering areas for waterbirds in the Caspian Sea region. Previous studies revealed increased exposure to metals in some species of waterbirds using these wetlands. In this study, we examined concentrations of cadmium (Cd), chromium (Cr), iron (Fe), lead (Pb), and zinc (Zn) in kidneys, liver, and pectoral muscle of wintering Gadwall (Anas strepera) and Common Teal (Anas crecca) collected in 2012. Read More

    Serum Copper Homeostasis in Hypertensive Intracerebral Hemorrhage and its Clinical Significance.
    Biol Trace Elem Res 2018 Jan 11. Epub 2018 Jan 11.
    Department of Microbiology and Immunology, Shantou University Medical College, Shantou, 515041, China.
    This study was to investigate the alterations of serum copper homeostasis after hypertensive intracerebral hemorrhage (ICH), which is not yet clear. We recruited 85 hypertensive ICH patients and determined their serum levels of total copper (TCu), small molecule copper (SMC), and ceruloplasmin (Cp). Sera from 32 healthy persons and 12 primary hypertension patients were collected and analyzed as well. Read More

    The Influences of Chromium Supplementation on Glycemic Control, Markers of Cardio-Metabolic Risk, and Oxidative Stress in Infertile Polycystic ovary Syndrome Women Candidate for In vitro Fertilization: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Biol Trace Elem Res 2018 Jan 6. Epub 2018 Jan 6.
    Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, I.R, Iran.
    This study was carried out to investigate the effects of chromium intake on glycemic control, markers of cardio-metabolic risk, and oxidative stress in infertile polycystic ovary syndrome (PCOS) women candidate for in vitro fertilization (IVF). This randomized double-blind, placebo-controlled trial was done among 40 subjects with infertile PCOS candidate for IVF, aged 18-40 years old. Individuals were randomly allocated into two groups to take either 200 μg/day of chromium (n = 20) or placebo (n = 20) for 8 weeks. Read More

    Lanthanum-Induced Mucosal Alterations in the Stomach (Lanthanum Gastropathy): a Comparative Study Using an Animal Model.
    Biol Trace Elem Res 2018 Jan 4. Epub 2018 Jan 4.
    Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan.
    Lanthanum (La) carbonate (LC) is one of the most potent phosphate binders that prevents the elevation of serum phosphate levels in patients with end-stage renal diseases undergoing dialysis. LC binds strongly to dietary phosphate and forms insoluble complexes that pass through the gastrointestinal tract. La deposition in patients treated with LC is a recently documented finding particularly observed in gastric mucosa. Read More

    The Adverse Effects of Se Toxicity on Inflammatory and Immune Responses in Chicken Spleens.
    Biol Trace Elem Res 2018 Jan 4. Epub 2018 Jan 4.
    Engineering Research Center of Biomass Materials, Ministry of Education, Southwest University of Science and Technology, Mianyang, Sichuan, 621010, China.
    Selenium (Se) is an essential trace element, but excessive intake of Se could induce Se poisoning, and result in various health problems. NF-κB regulated many molecules of the immune response and the inflammatory response, and Th1/Th2 balance played a key in the regulation of immune response. The aim of this study is to investigate the role of NF-κB pathway and Th1/Th2 imbalance in the adverse influence of Se poisoning on chicken spleens. Read More

    Biomonitoring of Trace Metals in the Keban Dam Reservoir (Turkey) Using Mussels (Unio elongatulus eucirrus) and Crayfish (Astacus leptodactylus).
    Biol Trace Elem Res 2018 Jan 3. Epub 2018 Jan 3.
    Aquaculture Research Institute, Elazığ, Turkey.
    Freshwater mussels and crayfish are commonly used as biomonitors of trace metals. In the present study, the concentrations of ten metals were determined in mussels (Unio elongatulus eucirrus) and crayfish (Astacus leptodactylus) collected from the Keban Dam Reservoir in Turkey. The significant spatial differences in concentrations of studied metals except As in mussels were not found. Read More

    Acute and Cumulative Effects of Unmodified 50-nm Nano-ZnO on Mice.
    Biol Trace Elem Res 2018 Jan 2. Epub 2018 Jan 2.
    College of Animal Science and Veterinary Medicine, Henan University of Science and Technology, No. 263 Kaiyuan Road, Luoyang, Henan, 471023, People's Republic of China.
    Nanometer zinc oxide (nano-ZnO) is widely used in diverse industrial and agricultural fields. Due to the extensive contact humans have with these particles, it is crucial to understand the potential effects that nano-ZnO have on human health. Currently, information related to the toxicity and mechanisms of nano-ZnO is limited. Read More

    Protective Effects of Selenium on Cyclophosphamide-Induced Oxidative Stress and Kidney Injury.
    Biol Trace Elem Res 2017 Dec 30. Epub 2017 Dec 30.
    Faculty of Medicine Department of Physiology, Eskisehir Osmangazi University, Eskisehir, Turkey.
    Cyclophosphamide (CP) is a common anticancer drug, but its use in cancer treatment is limited due to its severe toxicities induced mainly by oxidative stress in normal cells. Reactive oxygen species (ROS) lead to multiple organ injuries, including the kidneys. Selenium (Se) is a nutritionally essential trace element with antioxidant properties. Read More

    The Divalent Elements Changes in Early Stages of Chronic Kidney Disease.
    Biol Trace Elem Res 2017 Dec 28. Epub 2017 Dec 28.
    Department of Medical Laboratory Science and Biotechnology, Fooyin University, Kaohsiung, Taiwan.
    As the glomerular filtration rate (GFR) decreases, it can cause imbalance in some divalent elements. These imbalances can cause increased oxidative stress in patients with renal impairment. The aim of present study was to investigate the changes of these divalent elements with CKD progression. Read More

    Determination of Heavy Metals in Almonds and Mistletoe as a Parasite Growing on the Almond Tree Using ICP-OES or ICP-MS.
    Biol Trace Elem Res 2017 Dec 28. Epub 2017 Dec 28.
    Department of Chemistry, Faculty of Science, Ankara University, 06100, Ankara, Turkey.
    In this study, the elements of Al, As, B, Ba, Ca, Cd, Co, Cr, Cu, Fe, K, Mg, Mn, Mo, Ni, Sr, Pb, Ti, and Zn were determined in the leaves, fruits, and branches of mistletoe, (Viscum albüm L.), used as a medicinal plant, and in the leaves, branches and barks of almond tree which mistletoe grows on. The aim of the study is to investigate whether the mistletoe are more absorbent than the almond tree in terms of the heavy metal contents and the determination of the amount of the elements penetrated into the mistletoe from the almond tree. Read More

    Hair Mineral and Trace Element Contents as Reliable Markers of Nutritional Status Compared to Serum Levels of These Elements in Children Newly Diagnosed with Inflammatory Bowel Disease.
    Biol Trace Elem Res 2017 Dec 27. Epub 2017 Dec 27.
    Department of Pediatrics, Seoul National University Bundang Hospital, 82 Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-707, South Korea.
    Patients with inflammatory bowel disease (IBD) are at high risk for nutritional deficiencies because of long-term inflammation in the gut mucosa and decreased oral intake. Because inflammation responses affect serum micronutrient concentrations, serum levels are limited in reflecting body nutrient status in acute and chronic illness. We investigated the usefulness of measuring trace elements in hair as reliable markers of nutritional status compared to serum levels in children with IBD. Read More

    The Antagonistic Effect of Selenium on Lead-Induced Immune Dysfunction via Recovery of Cytokine and Heat Shock Protein Expression in Chicken Neutrophils.
    Biol Trace Elem Res 2017 Dec 20. Epub 2017 Dec 20.
    College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
    Lead (Pb) is a ubiquitous and toxic heavy metal and it can damage the immune system in humans and animals. Many researchers have reported that Selenium (Se) could possess various pharmacological effects in mammals. However, few studies have been carried out to investigate the protective role of Se in birds, especially in chickens. Read More

    Serum Concentration of Macro-, Micro-, and Trace Elements in Silver Fox (Vulpes vulpes) and Their Interrelationships with Morphometric, Densitometric, and Mechanical Properties of the Mandible.
    Biol Trace Elem Res 2017 Dec 20. Epub 2017 Dec 20.
    II Department of Radiology, Medical University in Lublin, ul. Staszica 16, 20-081, Lublin, Poland.
    The optimal content of macro-, micro-, and trace elements in tissues ensures proper systemic growth and development and optimal health status in animals and humans. However, very little is known on the elemental content in the plasma compartment in Silver fox. The aim of this study was to determine the content of selected elements in serum obtained from 8-month-old female (N = 8) and male (N = 7) silver foxes. Read More

    Chronic Exposure to Water of Lake Qaroun Induced Metal-Related Testicular Damage and Endocrine Disruption in Male Fish.
    Biol Trace Elem Res 2017 Dec 18. Epub 2017 Dec 18.
    Department of Zoology, Faculty of Science, Cairo University, Giza, Egypt.
    The uncontrolled releasing of hazardous wastes into Lake Qaroun was adversely impacting the aquatic environment and its biota. Therefore, this approach was designed to investigate the impact of these discharges on the reproductive and testicular function of Oreochromis niloticus. Several biomarkers were applied on the testicular tissues as metal bioaccumulation levels, histological examination with recording the ovotestis appearance and antioxidant status after 45 days of exposure to 0, 10, 20, & 30% of Lake Qaroun water (LQW). Read More

    Effects of Zinc Supplementation During In Vitro Maturation on Meiotic Maturation of Oocytes and Developmental Capacity in Yak.
    Biol Trace Elem Res 2017 Dec 15. Epub 2017 Dec 15.
    College of Life Science and Technology, Southwest Minzu University, Chengdu, Sichuan, 610041, China.
    Zinc (Zn) is an essential trace element that is required during mammalian developmental processes. The objective of this study was to investigate the effects of Zn supplementation during in vitro maturation (IVM) on the developmental capacity of yak (Bos grunniens) oocytes. Cumulus expansion, nuclear maturation, intracellular glutathione (GSH), reactive oxygen species (ROS) levels, superoxide dismutase (SOD) activity, subsequent embryonic development, and the expression of Zn transporters (ZnTs) and Zrt and Irt-like proteins (ZiPs) were evaluated. Read More

    Effect of Arsenic Exposure on NRF2-KEAP1 Pathway and Epigenetic Modification.
    Biol Trace Elem Res 2017 Dec 15. Epub 2017 Dec 15.
    Department of Environmental and Biological Monitoring, Nofer Institute of Occupational Medicine, St. Teresy 8, 91-348, Lodz, Poland.
    Arsenic (As) is a known toxic element and carcinogen. Transcription factor nuclear factor-erythroid 2-related factor 2 (NRF2) controls cellular adaptation to oxidants and electrophiles by inducing antioxidant genes in response to redox stress. To explore associations between As level and NRF2-regulated cytoprotective genes expression, an observational study was conducted in a population of 61 occupationally exposed men with median (Me) age 50 years (interquartile range (IQR) 42-54) and in a control group of 52 men aged 40 (IQR 31-51. Read More

    Cadmium Testicular Toxicity in Male Wistar Rats: Protective Roles of Zinc and Magnesium.
    Biol Trace Elem Res 2017 Dec 14. Epub 2017 Dec 14.
    Department of Anatomy Sciences, Isfahan University of Medical Scienses, Isfahan, Iran.
    Cadmium (Cd) is a highly toxic element, which may cause toxicity to most organs in the body. Zinc (Zn) and magnesium (Mg) are essential minerals with probable benefits on Cd harmful effects. Finding an efficient and non-pathological treatment against Cd toxicity seems promising. Read More

    Anemia and Iron Status Among Different Body Size Phenotypes in Chinese Adult Population: a Nation-Wide, Health and Nutrition Survey.
    Biol Trace Elem Res 2017 Dec 9. Epub 2017 Dec 9.
    Department of Laboratory Medicine, China-Japan Friendship Hospital, No. 2 Yinghua East Rd, Beijing, 100029, China.
    Previous studies have shown that there is a controversial relationship between iron homeostasis and obesity. This study aims to explore the relationship of anemia and iron status with different body size phenotypes in adult Chinese population. Using information on iron status-related parameters and lifestyle data from 8462 participants of the 2009 wave of China Health and Nutrition Survey (2009 CHNS), we performed multivariable logistic regression analyses to estimate the odds ratios (ORs) for the risk of anemia and iron parameters according to different body size phenotypes. Read More

    Effect of Oral Zinc Supplementation on the Thiol Oxido-Reductive Index and Thiol-Related Enzymes in Seminal Plasma and Spermatozoa of Iraqi Asthenospermic Patients.
    Biol Trace Elem Res 2017 Dec 8. Epub 2017 Dec 8.
    Chemistry Department, College of Science, University of Babylon, Hillah, Iraq.
    A thiol group plays an essential role in sperm metabolism and the antioxidative defense state. Zinc is the second most abundant element in the human body, following iron. The present study was conducted to study the effect of zinc supplementation on the characteristics of semen along with thiol and thiol-related enzymes in semen of asthenospermic patients. Read More

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