15 results match your criteria Biological Rhythm Research[Journal]

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The mutation impairs circadian locomotor activity.

Biol Rhythm Res 2019 8;50(3):375-388. Epub 2018 Mar 8.

Biology Department, Skidmore College, Saratoga Springs, NY USA, 518-580-5082.

We investigated effects of mutation ap on circadian locomotor activity, eclosion rhythms, and transcript levels of and in . We investigated circadian locomotor activity and eclosion rhythms in and wild-type flies, their F1 and F2 offspring, and wingless mutants and show that disrupts circadian locomotor rhythms in a genetically recessive manner, that is not caused by the absence of wings. The strain also showed impaired circadian activity rhythms, providing independent evidence for a significant role of in circadian locomotor rhythm expression. Read More

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http://dx.doi.org/10.1080/09291016.2018.1447353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474370PMC

Haloperidol, but not olanzapine, may affect expression of genes in human glioblastoma cell line.

Biol Rhythm Res 2016 11 1;47(6):865-871. Epub 2016 Jul 1.

Department of Clinical Pharmacology, Medical University of Łódź , Łódź , Poland.

: There is barely any evidence of antipsychotic drugs affecting the molecular clockwork in human, yet it is suggested that clock genes are associated with dopaminergic transmission, i.e. the main target of this therapeutics. Read More

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http://dx.doi.org/10.1080/09291016.2016.1202379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044774PMC
November 2016
7 Reads

Circadian expressions of cardiac ion channel genes in mouse might be associated with the central clock in the SCN but not the peripheral clock in the heart.

Biol Rhythm Res 2013 Aug 6;44(4):519-530. Epub 2012 Aug 6.

Department of Cardiology, Fujita Health University School of Medicine, Toyoake, Japan.

Significant circadian variations exist in the frequency of cardiac arrhythmia, but few studies have examined the relation between cardiac ion channels genes and biological clocks. We investigated this relation using suprachiasmatic nuclei lesion (SCNX) and pharmacological autonomic nervous system block (ANSB) mice. Significant 24-h variations were observed in the expression of clock genes Per2, Bmal1, and Dbp and ion channel genes KCNA5, KCND2, KCHIP2, and KCNK3 in the control mice hearts. Read More

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http://dx.doi.org/10.1080/09291016.2012.704801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570950PMC
August 2013
8 Reads

Short wavelength light administered just prior to waking: a pilot study.

Biol Rhythm Res 2013 Jan 15;44(1):13-32. Epub 2012 Feb 15.

Center for Sleep and Circadian Neurobiology, Division of Sleep Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Bright light in the blue-green range, administered in the early morning hours (prior to waking) may be particularly effective in shifting circadian rhythms and may increase gonadotropin production. Accordingly, we tested the feasibility and utility of a mask that emits bright blue/green light (compared to a similar mask that emitted a dim red light) towards the end of sleep in a randomized, placebo-controlled pilot study. The study included a 3-day baseline period, immediately followed by a 12-day intervention period. Read More

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http://dx.doi.org/10.1080/09291016.2011.632578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529958PMC
January 2013
1 Read

Daily oscillation of glutathione redox cycle is dampened in the nutritional vitamin A deficiency.

Biol Rhythm Res 2012 Jul 1;43(4):351-372. Epub 2011 Aug 1.

Laboratory of Chronobiology, Multidisciplinary Institute of Biological Research San Luis (IMIBIO-SL), National Council of Science and Technology (CONICET), National University of San Luis (UNSL). Chacabuco y Pedernera, D5700HHW, San Luis, Argentina.

Examples of hormonal phase-shifting of circadian gene expression began to emerge a few years ago. Vitamin A fulfills a hormonal function by binding of retinoic acid to its nuclear receptors, RARs and RXRs. We found retinoid- as well as clock-responsive sites on regulatory regions of Glutathione reductase (GR) and Glutathione peroxidase (GPx) genes. Read More

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http://dx.doi.org/10.1080/09291016.2011.593847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438693PMC
July 2012
2 Reads

The Effects of 24-hour Sleep Deprivation on the Exploration-Exploitation Trade-off.

Biol Rhythm Res 2011 Apr;42(2):99-110

Department of Psychology, University of Texas at Austin, Austin, United States.

Sleep deprivation has a complex set of neurological effects that go beyond a mere slowing of mental processes. While cognitive and perceptual impairments in sleep deprived individuals are widespread, some abilities remain intact. In an effort to characterize these effects, some have suggested an impairment of complex decision making ability despite intact ability to follow simple rules. Read More

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http://dx.doi.org/10.1080/09291011003726532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113536PMC
April 2011
1 Read

Procedures for numerical analysis of circadian rhythms.

Biol Rhythm Res 2007 ;38(4):275-325

Circadian Rhythm Laboratory, University of South Carolina, SC, USA.

This article reviews various procedures used in the analysis of circadian rhythms at the populational, organismal, cellular and molecular levels. The procedures range from visual inspection of time plots and actograms to several mathematical methods of time series analysis. Computational steps are described in some detail, and additional bibliographic resources and computer programs are listed. Read More

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http://dx.doi.org/10.1080/09291010600903692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663600PMC
January 2007
13 Reads

A procedure of multiple period searching in unequally spaced time-series with the Lomb-Scargle method.

Biol Rhythm Res 1999 ;30(2):149-77

Unit for Experimental Psychiatry, Univ. of Pennsylvania School of Medicine, Philadelphia, USA.

Periodogram analysis of unequally spaced time-series, as part of many biological rhythm investigations, is complicated. The mathematical framework is scattered over the literature, and the interpretation of results is often debatable. In this paper, we show that the Lomb-Scargle method is the appropriate tool for periodogram analysis of unequally spaced data. Read More

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http://dx.doi.org/10.1076/brhm.30.2.149.1424DOI Listing
January 2002

The issue of significant features in random noise.

Authors:
M Schimmel

Biol Rhythm Res 2001 Jul;32(3):355-60

Department of Geophysics, University of Sao Paulo, Brazil.

With respect to the first example in Schimmel (2001), Van Dongen et al. (2001) conclude from their Lomb-Scargle analysis that the noise I used 'contains new periodicities that are added to the signal (these periodicities by themselves resemble a harmonic series of a 38-hour rhythm).' They infer that 'the variance of the added noise is about five times as large as the variance of the signal' causing the detection of the new significant periodicities in the noise prior to the 24-h bimodal rhythm. Read More

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http://dx.doi.org/10.1076/brhm.32.3.355.1346DOI Listing

Emphasizing difficulties in the detection of rhythms with Lomb-Scargle periodograms.

Authors:
M Schimmel

Biol Rhythm Res 2001 Jul;32(3):341-5

Department of Geophysics, University of Sao Paulo, Brazil.

The Lomb-Scargle periodogram was introduced in astrophysics to detect sinusoidal signals in noisy unevenly sampled time series. It proved to be a powerful tool in time series analysis and has recently been adapted in biomedical sciences. Its use is motivated by handling non-uniform data which is a common characteristic due to the restricted and irregular observations of, for instance, free-living animals. Read More

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http://dx.doi.org/10.1076/brhm.32.3.341.1340DOI Listing
July 2001
1 Read

A brief response to Dr. Schimmel's reply.

Biol Rhythm Res 2001 Jul;32(3):361-2

Unit for Experimental Psychiatry, University of Pennsylvania School of Medicine, PA, USA.

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http://dx.doi.org/10.1076/brhm.32.3.361.1344DOI Listing

Analysis of problematic time series with the Lomb-Scargle Method, a reply to 'emphasizing difficulties in the detection of rhythms with Lomb-Scargle periodograms'.

Biol Rhythm Res 2001 Jul;32(3):347-54

Unit for Experimental Psychiatry, University of Pennsylvania School of Medicine, PA, USA.

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http://dx.doi.org/10.1076/brhm.32.3.347.1348DOI Listing

Estimates of the daily phase and amplitude of the endogenous component of the circadian rhythm of core temperature in sedentary humans living nychthemerally.

Biol Rhythm Res 2000 Feb;31(1):88-107

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, UK.

Fifteen healthy female subjects were studied for eight days while living conventionally. Subjects were free to choose the ways they spent their time within a framework of regular times of retiring and rising; in practice, much of the waking time was spent in sedentary activities. Nine of the subjects were aware of the natural light-dark cycle, this approximating to a 12:12 L:D schedule at the time of year when the study took place. Read More

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http://dx.doi.org/10.1076/0929-1016(200002)31:1;1-0;FT088DOI Listing
February 2000

Human sleep-wake cycles in the high Arctic: effects of unusual photoperiodicity in a natural setting.

Biol Rhythm Res 1995 Nov;26(5):582-92

Department of Parks, Recreation, and Tourism, Lincoln University.

Studies of human circadian rhythms are typically conducted in artificial environments that are low in ecological validity. In the current study, six subjects and the field director lived in temporal isolation in a completely natural environment with constant daylight (a high Arctic research camp) for six weeks. Detailed daily sleep logs were kept. Read More

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http://dx.doi.org/10.1080/09291019509360360DOI Listing
November 1995

Impact of microgravity and hypergravity on free-running circadian rhythm of the desert beetle Trigonoscelis gigas Reitt.

Biol Rhythm Res 1994 Apr;25(2):168-77

Institute of Biomedical Problems, Moscow, Russia.

Free-running circadian rhythms of locomotor activity of Tenebrionid beetles Trigonoscelis gigas Reitt., taken from the Turkmenian sand desert, were monitored in DD. The effects of microgravity --11 days in space flight aboard the Russian BION-10 "COSMOS" satellite, and of 2G hypergravity--seven days on a centrifuge, were determined. Read More

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http://dx.doi.org/10.1080/09291019409360284DOI Listing
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