- Oleg N Tikhodeyev
Biol Rev Camb Philos Soc 2018 May 22. Epub 2018 May 22.
Department of Genetics & Biotechnology, Saint-Petersburg State University, Saint-Petersburg 199034, Russia.
Although epigenetic inheritance (EI) is a rapidly growing field of modern biology, it still has no clear place in fundamental genetic concepts which are traditionally based on the hereditary role of DNA. Moreover, not all mechanisms of EI attract the same attention, with most studies focused on DNA methylation, histone modification, RNA interference and amyloid prionization, but relatively few considering other mechanisms such as stable inhibition of plastid translation. Herein, we discuss all known and some hypothetical mechanisms that can underlie the stable inheritance of phenotypically distinct hereditary factors that lack differences in DNA sequence. Read More