910 results match your criteria Biological Research For Nursing [Journal]


Systematic Review of the Kynurenine Pathway and Psychoneurological Symptoms Among Adult Cancer Survivors.

Biol Res Nurs 2020 Jun 30:1099800420938141. Epub 2020 Jun 30.

Department of Biobehavioral Health Science, College of Nursing, University of Illinois, Chicago, IL, USA.

The co-occurrence of multiple psychoneurological symptoms, including pain, sleep disturbance, fatigue, depression, anxiety, and cognitive disturbance among adult cancer survivors led us to question which common biological mechanisms are shared among these conditions. Variances in tryptophan (Trp) levels and downstream metabolites of the kynurenine (Kyn) metabolic pathway are known to affect immune response and psychoneurological symptoms. The objective of this systematic review was to help us (a) better understand the role of the Kyn pathway in psychoneurological symptoms among adult cancer survivors and (b) identify common significant biomarkers across psychoneurological symptoms as a guide for future research. Read More

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http://dx.doi.org/10.1177/1099800420938141DOI Listing

Early Ambulation After Injury Is Associated With Increased Muscle Size and Strength.

Biol Res Nurs 2020 Jun 19:1099800420934873. Epub 2020 Jun 19.

UK HealthCare, University of Kentucky, Lexington, KY, USA.

Background: Trauma and management of injuries can result in reduction or loss of mobility, which can lead to skeletal muscle deconditioning and sustained disability. Prior investigators have examined changes in skeletal muscle due to injury and immobility separately. The muscular consequences of combined immobility and trauma have not been systematically investigated. Read More

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http://dx.doi.org/10.1177/1099800420934873DOI Listing

Using Salivary Cortisol as an Objective Measure of Physiological Stress in People With Dementia and Chronic Pain: A Pilot Feasibility Study.

Biol Res Nurs 2020 Jun 18:1099800420934543. Epub 2020 Jun 18.

Menzies Health Institute Queensland, Griffith University, Australia.

Background: Pain can elevate stress in people with dementia. Although salivary cortisol is used as a biomarker of stress in people with dementia, few studies have reported the feasibility of collection methods to assess salivary cortisol in nursing home residents with both dementia and chronic pain.

Objective: To explore the feasibility of collecting cortisol via salivary swab as an indicator of stress in people with dementia and chronic pain. Read More

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http://dx.doi.org/10.1177/1099800420934543DOI Listing

Exploring Biologic Correlates of Cancer-Related Fatigue in Men With Prostate Cancer: Cell Damage Pathways and Oxidative Stress.

Biol Res Nurs 2020 Jun 9:1099800420933347. Epub 2020 Jun 9.

Symptom Biology Unit, National Institute of Nursing Research, National Institutes of Health, Bethesda, MD, USA.

The pathobiology of cancer-related fatigue (CRF) remains elusive, hindering the development of targeted treatments. Radiation therapy (RT), a common treatment for men with prostate cancer, induces cell damage through the generation of free radicals and oxidative stress. We hypothesized that disruption in cellular responses to this surge of nonphysiological oxidative stress might contribute to CRF in men with prostate cancer treated with RT. Read More

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http://dx.doi.org/10.1177/1099800420933347DOI Listing

Effects of Environmental Enrichment on Neurotrophins in an MPTP-Induced Parkinson's Disease Animal Model: A Randomized Trial.

Biol Res Nurs 2020 Jun 4:1099800420931183. Epub 2020 Jun 4.

Department of Nursing, Kunsan National University, 558, Daehak-ro, Gunsan-si, Jeonllabuk-do, Republic of Korea.

The aim of this study was to investigate the effect of environmental enrichment (EE) on neurotrophin expression in an animal model of Parkinson's disease (PD). PD was induced via intraperitoneal injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Male mice ( = 42) were randomly divided into 3 groups: control, MPTP + standard condition (SC), and MPTP + EE. Read More

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http://dx.doi.org/10.1177/1099800420931183DOI Listing

Plasma 25-Hydroxyvitamin D Level at Admission Predicts Unfavorable Outcome in Intensive Care Unit Patients.

Biol Res Nurs 2020 Jul 12;22(3):388-396. Epub 2020 May 12.

University of Tunis El Manar, Faculty of Medicine of Tunis, Tunis, Tunisia.

Introduction: Patients in intensive care units (ICUs) are at high risk of unfavorable outcomes. Considering the role of vitamin D (Vit D) in cardiovascular and immune functions, Vit D deficiency could affect ICU patients' outcomes. This study aimed to evaluate Vit D status and its predictive value for outcome in ICU patients. Read More

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http://dx.doi.org/10.1177/1099800420923746DOI Listing

Genetic Variation Near chrXq22-q23 Is Linked to Emotional Functioning in Cystic Fibrosis.

Biol Res Nurs 2020 Jul 11;22(3):319-325. Epub 2020 May 11.

Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, USA.

Introduction: Cystic fibrosis (CF) is an autosomal recessive disease that affects many organ systems, most notably the pulmonary and gastrointestinal systems. Through genome-wide association studies, multiple genetic regions modifying CF-related pulmonary and gastrointestinal symptoms have been identified, but translation of these findings to clinical benefit remains elusive. Symptom variation in CF patients has been associated with changes in health-related quality of life (HRQOL), but the relationship between CF symptom-modifying genetic loci and HRQOL has not been explored. Read More

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http://dx.doi.org/10.1177/1099800420924125DOI Listing

The Effect of Noise in the Intensive Care Unit on the Oxidative Stress Response in Rats.

Biol Res Nurs 2020 Jul 11;22(3):397-402. Epub 2020 May 11.

Department of Surgical Nursing, Faculty of Nursing, Aydin Adnan Menderes University, Aydin, Turkey.

Objective: The objective of this study was to determine the effect of noise in the intensive care unit (ICU) on oxidative stress in a rat model.

Method: This study had both a descriptive and a randomized controlled experimental stage. In the descriptive stage, to create a laboratory model of noise in the ICU, the noise level was measured for 24 hr on a randomly selected day in a surgical ICU, and voice recording was performed using a sound recording device. Read More

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http://dx.doi.org/10.1177/1099800420923397DOI Listing

Synergistic Effect of Low Neutrophil-Lymphocyte Ratio With Physical Activity on Quality of Life in Type 2 Diabetes Mellitus: A Community-Based Study.

Biol Res Nurs 2020 Jul 11;22(3):378-387. Epub 2020 May 11.

Post-Baccalaureate Program in Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan, R.O.C.

Background: Physical inactivity and Type 2 diabetes mellitus (T2DM)-associated inflammatory biomarkers are correlated with poor quality of life (QoL). However, no study has investigated the synergistic effect of physical activity (PA) and lower neutrophil-lymphocyte ratio (NLR) on QoL.

Objective: We examined the independent and synergistic effects of PA and inflammatory biomarkers on three domains of QoL in T2DM. Read More

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http://dx.doi.org/10.1177/1099800420924126DOI Listing

Lipidome Profiles Are Related to Depressive Symptoms and Preterm Birth Among African American Women.

Biol Res Nurs 2020 Jul 8;22(3):354-361. Epub 2020 May 8.

College of Nursing, University of Central Florida, Orlando, FL, USA.

African American women have the highest rate of preterm birth (PTB; <37 completed weeks' gestation) of any racial and ethnic group in the United States (14.1%). Depressive symptoms (DS) have been linked to PTB risk of African American women. Read More

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http://dx.doi.org/10.1177/1099800420923032DOI Listing

Effects of Far-Infrared Therapy on Foot Circulation Among Hemodialysis Patients With Diabetes Mellitus.

Biol Res Nurs 2020 Jul 5;22(3):403-411. Epub 2020 May 5.

Institute of Long-Term Care, Mackay Medical College, New Taipei City.

Background: Far-infrared radiation (FIR) therapy improves vessel dilation, circulation, vessel endothelial function, and angiogenesis and reduces atherosclerosis. However, evidence of FIR therapy's effects on foot circulation among diabetic patients undergoing hemodialysis is scarce.

Aim: To determine whether FIR therapy improves foot circulation in diabetic patients undergoing hemodialysis. Read More

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http://dx.doi.org/10.1177/1099800420923730DOI Listing

Exercise-Induced Premature Ventricular Contractions Are Associated With Myocardial Ischemia Among Asymptomatic Adult Male Firefighters: Implications for Enhanced Risk Stratification.

Biol Res Nurs 2020 Jul 28;22(3):369-377. Epub 2020 Apr 28.

University of Rochester School of Nursing, NY, USA.

Background: Exercise-induced premature ventricular contractions (EI-PVCs) are associated with an increased risk of cardiovascular disease among asymptomatic adult males, but the underlying mechanisms remain understudied. Myocardial ischemia due to cardiovascular disease reduces coronary blood flow, may impair exercise performance, and initiates EI-PVCs; thus, EI-PVCs may be an early indicator of cardiovascular disease.

Objective: The objective of this study was to determine whether EI-PVCs are associated with myocardial ischemia and reduced exercise performance among asymptomatic adult firefighters. Read More

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http://dx.doi.org/10.1177/1099800420921944DOI Listing

Animal-Assisted Activity in Critically Ill Older Adults: A Randomized Pilot and Feasibility Trial.

Biol Res Nurs 2020 Jul 22;22(3):412-417. Epub 2020 Apr 22.

Cizik School of Nursing, The University of Texas Health Science Center at Houston, TX, USA.

Background: Limited evidence suggests the efficacy of animal-assisted activities (AAA) in improving biobehavioral stress responses in older patients in intensive care units (ICUs).

Objectives: To assess the feasibility of an AAA (dog) intervention for improving biobehavioral stress response, measured by self-reported stress and anxiety and salivary cortisol, C-reactive protein, and interleukin-1β in older ICU patients, we examined enrollment, attrition, completion, data collection, and biobehavioral stress responses.

Methods: ICU patients ≥60 years old were randomly assigned to a 10-min AAA intervention or control/usual ICU care. Read More

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http://dx.doi.org/10.1177/1099800420920719DOI Listing

Occurrence of and Factors Associated With the Presence of Aflatoxin M in Breast Milk of Mothers in Fethiye, Turkey.

Biol Res Nurs 2020 Jul 21;22(3):362-368. Epub 2020 Apr 21.

Department of Medical Pharmacology, Faculty of Medicine, Karabük University, Turkey.

Aflatoxins comprise a group of mycotoxins that are found in the environment. Exposure to aflatoxins has been reported to cause serious health problems in humans. Since aflatoxin M (AFM) is secreted in breast milk, the exposure of infants to this toxin is an important concern. Read More

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http://dx.doi.org/10.1177/1099800420919900DOI Listing

The State of Data Science in Genomic Nursing.

Biol Res Nurs 2020 Jul 8;22(3):309-318. Epub 2020 Apr 8.

School of Nursing, Columbia University, New York, NY, USA.

Nurse scientists are generating, acquiring, distributing, processing, storing, and analyzing greater volumes of complex omics data than ever before. To take full advantage of big omics data, to address core biological questions, and to enhance patient care, however, genomic nurse scientists must embrace data science. Intended for readership with limited but expanding data science knowledge and skills, this article aims to provide a brief overview of the state of data science in genomic nursing. Read More

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http://dx.doi.org/10.1177/1099800420915991DOI Listing

The Effect of Age and Pain on Quantitative Sensory Testing Measurements After Moderate-to-Severe Traumatic Brain Injury: Preliminary Findings.

Biol Res Nurs 2020 Jul 25;22(3):341-353. Epub 2020 Mar 25.

Research Center and Trauma Division, Hôpital du Sacré-Coeur de Montréal, Québec, Canada.

Background: Chronic pain after moderate-to-severe traumatic brain injury (TBI) is associated with notable sensory alterations. Although the incidence of TBI is rapidly growing in older populations, elderly individuals have been largely excluded from sensory testing studies, thus limiting evidence regarding the influence of age on pain-related sensory alterations after TBI. This study aimed to investigate the effect of age on the sensory profiles of patients with and without chronic pain after moderate-to-severe TBI. Read More

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http://dx.doi.org/10.1177/1099800420912462DOI Listing

Response to Commentary on "Heart Rate Variability and Risk of All-Cause Death and Cardiovascular Events in Patients With Cardiovascular Disease: A Meta-Analysis of Cohort Studies".

Biol Res Nurs 2020 Jul 24;22(3):421-422. Epub 2020 Mar 24.

School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.

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http://dx.doi.org/10.1177/1099800420909142DOI Listing

PAV Haplotype Predicts Vegetable Consumption in Community-Dwelling Caucasian Adults at Risk for Cardiovascular Disease.

Biol Res Nurs 2020 Jul 24;22(3):326-333. Epub 2020 Mar 24.

College of Nursing, University of Kentucky, Lexington, KY, USA.

Introduction: A heart-healthy diet might reduce cardiovascular disease (CVD) risk. Genetic variants that affect taste are associated with food choices. This study aims to investigate the associations of the haplotype with consumption of sodium, sugar, saturated fats, and vegetables. Read More

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http://dx.doi.org/10.1177/1099800420913935DOI Listing

Genetic Variation in the Gene and Patient Outcomes Following Severe Traumatic Brain Injury.

Biol Res Nurs 2020 Jul 24;22(3):334-340. Epub 2020 Mar 24.

Department of Human Genetics, School of Nursing, University of Pittsburgh, PA, USA.

Traumatic brain injury (TBI) is a leading cause of death and disability, with more than 5 million people in the United States living with long-term complications related to TBI. This study examined the relationship between , the gene that codes for the protein p53, and outcome variability following severe TBI. The p53 protein impacts neuronal apoptosis following TBI, thus investigation into genetic variability as a prognosticator for TBI outcomes (mortality, Glasgow Outcome Scale [GOS], Neurobehavioral Rating Scale [NRS], and Disability Rating Scale [DRS]) is warranted. Read More

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http://dx.doi.org/10.1177/1099800420912335DOI Listing

The Role of Old Photos in Reminiscence Therapy in Elderly Women With Depressive Symptoms: A Functional Magnetic Resonance Imaging Study.

Biol Res Nurs 2020 04;22(2):234-246

Huaxi MR Research Center (HMRRC), Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Background: Although evidence shows that reminiscence therapy relieves depression in the elderly, few studies have explored its mechanisms and it is unclear whether old public photos rather than personal photos are effective prompts.

Objectives: The aims of this functional magnetic resonance imaging (fMRI) study with an event-related design were to explore whether old public photos can evoke autobiographical memories and compare brain-activation responses to photos between elderly women with depressive symptoms (DS) and normal controls (NC).

Methods: Elderly women with DS ( = 16) and NC ( = 18) were recruited from urban communities in Southwest China. Read More

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http://dx.doi.org/10.1177/1099800420908002DOI Listing

Obesogenic Toxicants in Breast Milk of Lactating Women: Investigation of a Risk Factor for Childhood Obesity.

Biol Res Nurs 2020 04;22(2):295-301

Clinical Research Institute, Texas Tech University Health Sciences Center, Lubbock, TX, USA.

Background: Persistent organic pollutants (POPs), dispersed in all environmental compartments, are associated with increased adipogenesis and body weight. These lipophilic toxicants bioaccumulate in the human body and get transferred from mothers to their offspring via the placental circulation and breast milk. The current study was designed to compare polychlorinated biphenyl (PCB) and hexachlorobenzene (HCB) concentrations between obese and normal-weight lactating women. Read More

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http://dx.doi.org/10.1177/1099800420909151DOI Listing

A Systematic Review of Biological Mechanisms and Chronic Pain Outcomes During Stress Reduction Interventions.

Biol Res Nurs 2020 04;22(2):205-216

School of Nursing, University of Connecticut, Storrs, CT, USA.

Background: Nonpharmacologic stress reduction interventions provide an opportunity to modify chronic pain trajectories; however, the biological mechanisms underlying these interventions are poorly understood.

Objectives: To examine clinical literature published in 2012-2018 with the goals of (1) identifying which biological mechanisms or biomarkers are currently being measured in nonpharmacologic stress reduction intervention studies for individuals with chronic pain and (2) evaluating the evidence to determine whether these stress reduction interventions lead to changes in (a) pain outcomes and/or (b) measured biomarkers.

Data Sources: Scientific articles in the electronic databases PubMed/Medline, Cumulative Index of Nursing and Allied Health Literature, PsychINFO, and SCOPUS following the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Read More

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http://dx.doi.org/10.1177/1099800420907964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273806PMC

Commentary on "Heart Rate Variability and Risk of All-Cause Death and Cardiovascular Events in Patients With Cardiovascular Disease: A Meta-Analysis of Cohort Studies".

Biol Res Nurs 2020 Jul 4;22(3):418-420. Epub 2020 Mar 4.

Department of Psychosomatic Medicine and Psychotherapy, Ulm University Medical Center, Ulm, Germany.

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http://dx.doi.org/10.1177/1099800420909420DOI Listing

The Obesity Paradox in Sepsis: A Theoretical Framework.

Biol Res Nurs 2020 04 17;22(2):287-294. Epub 2020 Feb 17.

Department of Adult Health and Nursing Systems, School of Nursing, Virginia Commonwealth University, Richmond, VA, USA.

Sepsis is a life-threatening syndrome that occurs in response to a severe infection. In recent years, the understanding of the pathobiology of sepsis has been refined, with research describing an altered host response as the underlying cause. Survivors of sepsis often have long hospital stays and suffer from subsequent frailty and long-term health consequences. Read More

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http://dx.doi.org/10.1177/1099800420905889DOI Listing
April 2020
1.341 Impact Factor

The Connection and Disconnection Between Microbiome and Metabolome: A Critical Appraisal in Clinical Research.

Biol Res Nurs 2020 Feb 4:1099800420903083. Epub 2020 Feb 4.

Center for Precision Medicine, Department of Internal Medicine, Section of Molecular Medicine, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC, USA.

Big data-driven omics research has led to a steep rise in investigations involving two of the most functional omes, the metabolome and microbiome. The former is touted as the closest to the phenotype, and the latter is implicated in general well-being and a plethora of human diseases. Although some research publications have integrated the concepts of the two domains, most focus their analyses on evidence solely originating from one or the other. Read More

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http://dx.doi.org/10.1177/1099800420903083DOI Listing
February 2020
1.341 Impact Factor

Real-Time Associations Between Glucose Levels and Fatigue in Type 2 Diabetes: Sex and Time Effects.

Biol Res Nurs 2020 04 3;22(2):197-204. Epub 2020 Feb 3.

Department of Biobehavioral Health Science, College of Nursing, University of Illinois at Chicago, Chicago, IL, USA.

Objective: Fatigue is a pervasive and serious complaint among aging adults with type 2 diabetes. Anecdotally, hyperglycemia was thought to cause fatigue, but prior cross-sectional analyses failed to find any relationship between glucose levels and fatigue. However, study methodology may have caused this relationship to be missed. Read More

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http://dx.doi.org/10.1177/1099800419898002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273801PMC

Metabolic Pathways Associated With Term Labor Induction Course in African American Women.

Biol Res Nurs 2020 04 27;22(2):157-168. Epub 2020 Jan 27.

Division of Pulmonary, Allergy, and Critical Care, Emory University, Atlanta, GA, USA.

Objectives: The purpose of this study was to evaluate differences in the metabolic pathways activated in late-pregnancy serum samples among African American women who went on to have term (≥37 weeks) labor induction requiring high total oxytocin doses to complete first-stage labor compared to those in similar women with low-oxytocin labor inductions.

Study Design: Case-control study ( = 27 women with labor induction with successful cervical ripening: 13 requiring the highest total doses of synthetic oxytocin to progress from 4- to 10-cm cervical dilation and 14 requiring the lowest total doses) with groups balanced on parity and gestational age. Serum samples obtained between 24 and 30 weeks' gestation were analyzed using ultra-high-resolution metabolomics. Read More

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http://dx.doi.org/10.1177/1099800419899730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273804PMC

Oxidative Stress Biomarker Decreased in Preterm Neonates Treated With Kangaroo Mother Care.

Biol Res Nurs 2020 04 24;22(2):188-196. Epub 2020 Jan 24.

Department of Basic Sciences, Division of Biochemistry, School of Medicine, Loma Linda University, Loma Linda, CA, USA.

Objective: Due to physiological and metabolic immaturity, prematurely born infants are at increased risk because of maternal separation in many neonatal intensive care units (NICUs). The stress induced from maternal-infant separation can lead to well-documented short-term physiologic instability and potentially lifelong neurological, sociological, or psychological sequelae. Based on previous studies of kangaroo mother care (KMC) that demonstrated improvement in physiologic parameters, we examined the impact of KMC on physiologic measures of stress (abdominal temperature, heart rate, oxygen saturation, perfusion index, near-infrared spectrometry), oxidative stress, and energy utilization/conservation in preterm infants. Read More

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http://dx.doi.org/10.1177/1099800419900231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273802PMC
April 2020
1.341 Impact Factor

Genes Involved in the HPA Axis and the Symptom Cluster of Fatigue, Depressive Symptoms, and Anxiety in Women With Breast Cancer During 18 Months of Adjuvant Therapy.

Biol Res Nurs 2020 04 7;22(2):277-286. Epub 2020 Jan 7.

Department of Health and Community Systems, School of Nursing, University of Pittsburgh, PA, USA.

This study aimed to (1) identify subgroups of women with breast cancer with the psychological symptom cluster (fatigue, depressive symptoms, and anxiety) during the first 18 months of adjuvant therapy and (2) explore associations between demographic and clinical characteristics and variations in genetic polymorphisms related to hypothalamic-pituitary-adrenal (HPA) axis function and predicted symptom trajectory subgroup membership. We obtained symptom data at 4 time points from baseline to 18 months of adjuvant therapy among 292 postmenopausal women with breast cancer. Genetic data were collected in a subgroup at baseline ( = 184). Read More

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http://dx.doi.org/10.1177/1099800419899727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273805PMC

Positive Association Between Serum Levels of High-Sensitivity C-Reactive Protein and Depression/Anxiety in Female, but Not Male, Patients With Type 2 Diabetes Mellitus.

Biol Res Nurs 2020 04 23;22(2):178-187. Epub 2019 Dec 23.

School of Nursing, Shandong University, Shandong, People's Republic of China.

Purpose: Patients with Type 2 diabetes (T2D) have increased risk of depression and anxiety. Evidence suggests that a heightened inflammatory state may contribute to this association. Females experience more depression and higher inflammation levels than males. Read More

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http://dx.doi.org/10.1177/1099800419894641DOI Listing
April 2020
1.341 Impact Factor

Relationship of Anxiety, Inflammation, and Telomere Length in Postpartum Women: A Pilot Study.

Biol Res Nurs 2020 04 20;22(2):256-262. Epub 2019 Dec 20.

Department of Obstetrics and Gynecology, NYU Langone Medical Center, NY, USA.

Background: The postpartum period can be a vulnerable time during which many women are prone to mood disturbances. Since telomere length (TL) is known to be associated with dysphoric moods, inflammation, and stress in many populations, this study's objective was to assess the relationships among TL, dysphoric moods, stress, and inflammation during the postpartum period.

Method: This cross-sectional pilot study is a secondary analysis of data collected in a larger parent study of anti-thyroid peroxidase (TPO) enzyme antibody positive versus negative women. Read More

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http://dx.doi.org/10.1177/1099800419890424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273803PMC

The Psychometric Properties of the Minnesota Tobacco Withdrawal Scale Among Patients With Mental Illness.

Biol Res Nurs 2020 04 19;22(2):247-255. Epub 2019 Dec 19.

The University of Kentucky College of Nursing, Lexington, KY, USA.

Background And Objectives: Approximately 65% of psychiatric inpatients experience moderate-to-severe nicotine withdrawal (NW), a set of symptoms appearing within 24 hr after an abrupt cessation or reduction of use of tobacco-containing products in those using nicotine daily for at least a couple of weeks. The Minnesota Tobacco Withdrawal Scale (MTWS) is a widely used instrument for detecting NW. However, the psychometric properties of the MTWS have not previously been examined among patients with serious mental illness (SMI) undergoing tobacco-free hospitalization. Read More

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http://dx.doi.org/10.1177/1099800419895573DOI Listing

Genetic Underpinnings of Musculoskeletal Pain During Treatment With Aromatase Inhibitors for Breast Cancer: A Biological Pathway Analysis.

Biol Res Nurs 2020 04 18;22(2):263-276. Epub 2019 Dec 18.

School of Nursing, University of Pittsburgh, PA, USA.

Background: Musculoskeletal pain (MSKP) is the most reported symptom during treatment with aromatase inhibitors (AIs) for breast cancer. The mechanisms underlying MSKP are multidimensional and not well understood. The goals of this biological pathway analysis were to (1) gain an understanding of the genetic variation and biological mechanisms underlying MSKP with AI therapy and (2) identify plausible biological pathways and candidate genes for future investigation. Read More

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http://dx.doi.org/10.1177/1099800419895114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273800PMC

Patient Position Affects Venodilation for Peripheral Intravenous Cannulation.

Biol Res Nurs 2020 04 13;22(2):226-233. Epub 2019 Dec 13.

Department of Health Science, Osaka University Graduate School of Medicine, Japan.

Background: Larger veins are associated with a higher rate of success of peripheral intravenous cannulation. Although patient position affects venodilation during central venous cannulation, the association between patient position and vein size for peripheral intravenous cannulation remains unclear.

Purpose: We examined the effect of seated versus supine positioning on vein size during peripheral intravenous cannulation before and after tourniquet application. Read More

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http://dx.doi.org/10.1177/1099800419893027DOI Listing

A Systematic Review of Taste Differences Among People With Eating Disorders.

Biol Res Nurs 2020 01 4;22(1):82-91. Epub 2019 Sep 4.

Sensory Science & Metabolism Unit, Biobehavioral Branch, Division of Intramural Research, Department of Health and Human Services, National Institutes of Health, Bethesda, MD, USA.

Background: Eating disorders are a significant cause of morbidity and mortality. The etiology and maintenance of eating-disorder symptoms are not well understood. Evidence suggests that there may be gustatory alterations in patients with eating disorders. Read More

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http://dx.doi.org/10.1177/1099800419872824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912928PMC
January 2020
1.341 Impact Factor

Relevance of Sex and Subtype in Patients With IBS: An Exploratory Study of Gene Expression.

Biol Res Nurs 2020 01;22(1):13-23

Digestive Disorders Unit, Division of Intramural Research, National Institute of Nursing Research, National Institutes of Health, Bethesda, MD, USA.

Background: Psychological state, stress level, and gastrointestinal function are intricately related and relevant to symptom exacerbation in patients with irritable bowel syndrome (IBS), but genetic contributors to this brain-gut connection are not fully understood. The purpose of this exploratory study was to compare gene expression in participants with IBS to that of healthy controls (HC) and to examine patterns of expression in participants with IBS by sex and IBS subtype.

Method: Participants were recruited to an ongoing protocol at the National Institutes of Health. Read More

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http://dx.doi.org/10.1177/1099800419889189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068753PMC
January 2020

High Coping Self-Efficacy Associated With Lower Sweat Inflammatory Cytokines in Adults: A Pilot Study.

Biol Res Nurs 2020 01 5;22(1):75-81. Epub 2019 Sep 5.

Center on Innovative Care in Aging, Johns Hopkins University School of Nursing, Baltimore, MD, USA.

Introduction/background: Chronic diseases, like diabetes and heart disease, are considered inflammatory conditions with elevated levels of the proinflammatory cytokines interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α) and the anti-inflammatory cytokine interleukin-10 (IL-10). Disease progression is not consistent from person to person. Psychosocial factors are hypothesized to play a modifying role. Read More

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http://dx.doi.org/10.1177/1099800419870607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068750PMC
January 2020

The Relationships of High-Sensitivity C-Reactive Protein and Homocysteine Levels With Disease Activity, Damage Accrual, and Cardiovascular Risk in Systemic Lupus Erythematosus.

Biol Res Nurs 2020 04 25;22(2):169-177. Epub 2019 Nov 25.

Department of Nursing, Health Sciences Faculty, University of Granada, Spain.

Results: hs-CRP correlated significantly with SLEDAI-2K ( = .036), SDI ( = .00), anti-dsDNA titers ( = . Read More

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http://dx.doi.org/10.1177/1099800419889192DOI Listing
April 2020
1.341 Impact Factor

Self-Reported Parenting Stress and Cortisol Awakening Response Following Mindfulness-Based Stress Reduction Intervention for Parents of Children With Developmental Delays: A Pilot Study.

Biol Res Nurs 2020 04 22;22(2):217-225. Epub 2019 Nov 22.

Department of Psychology, Loma Linda University, CA, USA.

Background: Many parents of children with developmental delays (DDs) experience high levels of parental stress, and young children with DDs are likely to exhibit clinical levels of behavioral problems. The reciprocal relationship between the two issues makes these families vulnerable to stress-related health risks. To address this, the current study aims to investigate the effectiveness of mindfulness-based stress reduction (MBSR) at reducing parent stress, as measured by both psychological self-report and a physiological biomarker. Read More

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http://dx.doi.org/10.1177/1099800419890125DOI Listing

Relationship Between Diurnal Cortisol Profile and Sleep Quality in Patients With Hepatocellular Carcinoma.

Biol Res Nurs 2020 01 19;22(1):139-147. Epub 2019 Nov 19.

School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.

Purpose: Hepatocellular carcinoma (HCC) is the second leading cause of cancer mortality worldwide. Sleep problems are common in HCC patients and may be attributable to disturbances in the circadian rhythm. Research into the role of circadian rhythms in sleep quality among HCC patients is lacking, however. Read More

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http://dx.doi.org/10.1177/1099800419881195DOI Listing
January 2020

Exploring Relationships Among Peripheral Amyloid Beta, Tau, Cytokines, Cognitive Function, and Psychosomatic Symptoms in Breast Cancer Survivors.

Biol Res Nurs 2020 01 10;22(1):126-138. Epub 2019 Nov 10.

School of Nursing; Department of Oncology, University of Texas at Austin, Austin, TX, USA.

Objective: Accelerated brain aging has been proposed to explain cancer-related cognitive impairment, but empirical evidence for this relationship is lacking. The purpose of this study was to evaluate amyloid beta (Aβ) and tau, biomarkers of neurodegeneration, in relation to cognition in breast cancer survivors (BCSs). We explored relationships among peripheral concentrations of Aβ42, Aβ-40, tau, and cytokines; cognitive function; and psychosomatic symptoms in a cohort of BCSs post-chemotherapy. Read More

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http://dx.doi.org/10.1177/1099800419887230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068749PMC
January 2020

Low-Intensity Exercise Training Increases Heart Rate Variability in Patients With Peripheral Artery Disease.

Biol Res Nurs 2020 01 4;22(1):24-33. Epub 2019 Nov 4.

Division of Vascular Surgery, Queens University, Kingston, Ontario, Canada.

Patients with peripheral artery disease (PAD), consistent with others with atherosclerotic occlusive disorders, have autonomic dysfunction (as measured by low heart rate variability [HRV]) that predisposes them to sympathetically mediated cardiac arrhythmias and sudden death. Exercise therapy has been shown to increase HRV in patients with coronary artery disease by increasing parasympathetic modulation of heart rate. This study quantified the circulatory and autonomic effects of a progressive, 12-week home-based, low-intensity (pain-free walking) exercise program in PAD and intermittent claudication. Read More

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http://dx.doi.org/10.1177/1099800419884642DOI Listing
January 2020

Effects of Heart Rate Variability Biofeedback in Patients With Acute Ischemic Stroke: A Randomized Controlled Trial.

Biol Res Nurs 2020 01 21;22(1):34-44. Epub 2019 Oct 21.

School of Nursing, National Defense Medical Center, Taipei.

Background: Autonomic dysfunction, cognitive impairment, and psychological distress are associated with poorer prognosis in patients with acute ischemic stroke (AIS). Heart rate variability (HRV) biofeedback (BF) improves autonomic dysfunction, cognitive impairment, and psychological distress in other patient populations, but its effect in patients with AIS is still unclear.

Objective: This study investigated the effects of an HRVBF intervention on autonomic function, cognitive impairment, and psychological distress in patients with AIS. Read More

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http://dx.doi.org/10.1177/1099800419881210DOI Listing
January 2020

Characterization of Spatial Learning and Sickness Responses in Aging Rats Following Recurrent Lipopolysaccharide Administration.

Biol Res Nurs 2020 01 10;22(1):92-102. Epub 2019 Oct 10.

School of Nursing, The University of Michigan-Flint, Flint, MI, USA.

Infections in older individuals can result in cognitive function decline, yet research is limited on how recurrent infections affect cognitive responses. Activation of the immune system results in sickness responses mediated by cytokines. This pilot study examined effects of a model of recurrent infection in aged, male Brown Norway rats on sickness responses, including spatial learning, and cytokine levels. Read More

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http://dx.doi.org/10.1177/1099800419875824DOI Listing
January 2020

Influence of Maternal Prepregnancy Obesity and Excessive Gestational Weight Gain on Maternal and Child Gastrointestinal Microbiome Composition: A Systematic Review.

Biol Res Nurs 2020 01 9;22(1):114-125. Epub 2019 Oct 9.

School of Nursing, University of Virginia, Charlottesville, VA, USA.

Background: Maternal obesity is a well-known risk factor for significant obstetric and neonatal complications. The influence of the gastrointestinal microbiome in the setting of maternal obesity during pregnancy is less understood. The purpose of this systematic review is to synthesize the literature on the relationships between maternal obesity and excessive gestational weight gain (EGWG) and the composition of maternal and child gastrointestinal microbiomes. Read More

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http://dx.doi.org/10.1177/1099800419880615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140212PMC
January 2020

Heart Rate Variability and Risk of All-Cause Death and Cardiovascular Events in Patients With Cardiovascular Disease: A Meta-Analysis of Cohort Studies.

Biol Res Nurs 2020 01 26;22(1):45-56. Epub 2019 Sep 26.

School of Nursing, College of Nursing, Taipei Medical University, Taipei.

Lower heart rate variability (HRV) is associated with a higher risk of cardiovascular events and mortality, although the extent of the association is uncertain. We performed a meta-analysis of cohort studies to elucidate the association between HRV and the risk of all-cause death or cardiovascular events in patients with cardiovascular disease (CVD) during a follow-up of at least 1 year. We searched four databases (PubMed, MEDLINE, Embase, and Cochrane Central Register of Controlled Trials) and extracted the adjusted hazard ratio (HR) from eligible studies. Read More

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http://dx.doi.org/10.1177/1099800419877442DOI Listing
January 2020
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Obesity and 1-Year Mortality in Adults After Sepsis: A Systematic Review.

Biol Res Nurs 2020 01 18;22(1):103-113. Epub 2019 Sep 18.

Department of Adult Health and Nursing Systems, School of Nursing, Virginia Commonwealth University, Richmond, VA, USA.

Purpose: In recent years, researchers have noted an "obesity paradox," where individuals with obesity survive sepsis at higher rates than their nonobese counterparts. This systematic review summarizes the literature on studies examining the association between obesity and 1-year mortality among patients admitted with sepsis, severe sepsis, or septic shock.

Materials And Methods: Using a comprehensive search strategy, a systematic review was conducted to identify studies examining the association of obesity and sepsis mortality. Read More

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http://dx.doi.org/10.1177/1099800419876070DOI Listing
January 2020
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1.341 Impact Factor

Immediate Prone Positioning After Massive Gastric Aspiration Reduces Lung Injury Possibly by Attenuating Interleukin-6-Mediated Lung-Tissue Inflammation in Pigs.

Biol Res Nurs 2020 01 17;22(1):64-74. Epub 2019 Sep 17.

School of Nursing, Capital Medical University, Beijing, China.

Gastric aspiration, which can cause acute, diffuse, inflammatory lung injury, is of particular concern in critically ill patients. This study aimed to determine the effects of immediate prone positioning on the degree of lung injury and inflammatory response induced by gastric aspiration. Following induction of gastric aspiration by injection of gastric fluid, 16 healthy pigs were randomized to one of two groups: supine position (SP) or prone position (PP). Read More

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http://dx.doi.org/10.1177/1099800419875521DOI Listing
January 2020
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The Effect of Transcranial Direct Current Stimulation on Inflammation in Older Adults With Knee Osteoarthritis: A Bayesian Residual Change Analysis.

Biol Res Nurs 2020 01 15;22(1):57-63. Epub 2019 Aug 15.

Cizik School of Nursing, University of Texas Health Science Center at Houston, Houston, TX, USA.

Transcranial direct current stimulation (tDCS) has demonstrated effectiveness in reducing clinical and experimental measures of pain in patients with chronic pain; however, research examining the mechanisms of action for the effects of tDCS has been lacking. The present study investigated the effect of active tDCS on measures of inflammation and stress. Older adults (aged 50-70 years) with knee osteoarthritis (OA) were randomly assigned to receive daily 20-min sessions of either tDCS ( = 20) or sham tDCS ( = 20) for 5 consecutive days. Read More

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http://dx.doi.org/10.1177/1099800419869845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068751PMC
January 2020