828 results match your criteria Biological Research For Nursing [Journal]


Associations of Hormonal Biomarkers With Mental Health and Healthy Behaviors Among Mothers of Very-Low-Birthweight Infants.

Biol Res Nurs 2019 Feb 14:1099800419829592. Epub 2019 Feb 14.

3 School of Nursing, Duke University, Durham, NC, USA.

Objectives:: To examine the concurrent use of self-report questionnaires and hormonal biomarkers, specifically levels of testosterone and cortisol, along with demographic variables and corrected age (CA) in the assessment of mental health and healthy behaviors among mothers of very-low-birthweight (VLBW, BW < 1,500 g) infants at five time points over 2 years post birth.

Method:: Data on 40 mothers from a neonatal intensive care unit of a tertiary medical center in the southeast United States were collected from the medical record, standard questionnaires for the mother (depressive symptoms, perceived stress, anxiety, mental health status, parenting stress, and healthy lifestyle behaviors), and biochemical measurement of maternal testosterone and cortisol using enzyme immunoassay at birth, 40 weeks' postmenstrual age, and 6, 12, and 24 months CA.

Results:: Maternal self-report of mental health improved from birth to 6 or 12 months then worsened at 24 months. Read More

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http://dx.doi.org/10.1177/1099800419829592DOI Listing
February 2019

Serum Albumin Trend Is a Predictor of Mortality in ICU Patients With Sepsis.

Biol Res Nurs 2019 Feb 5:1099800419827600. Epub 2019 Feb 5.

2 Department of Biomedical and Health Informatics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.

Introduction:: Patients admitted to the hospital with sepsis are 8 times more likely to die than patients with other diagnoses. There is no diagnostic test that clearly identifies the presence of the dysregulated host response that is central to sepsis. Researchers have identified serum albumin as a possible predictor of mortality in a number of critically ill patient populations. Read More

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http://dx.doi.org/10.1177/1099800419827600DOI Listing
February 2019

Neonatal Skin-to-Skin Contact: Implications for Learning and Autonomic Nervous System Function in Infants With Congenital Heart Disease.

Biol Res Nurs 2019 Feb 5:1099800419827599. Epub 2019 Feb 5.

5 The Ohio State University School of Health and Rehabilitation Sciences, Columbus, OH, USA.

Background:: Infants with complex congenital heart disease (CCHD) often develop neurodevelopmental disabilities. Cognitive abilities are associated with vagally mediated autonomic function. Skin-to-skin contact (SSC) interventions enhance infant neurodevelopment and autonomic function in other high-risk populations. Read More

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http://dx.doi.org/10.1177/1099800419827599DOI Listing
February 2019
1 Read

A Pilot Study Using a Multistaged Integrated Analysis of Gene Expression and Methylation to Evaluate Mechanisms for Evening Fatigue in Women Who Received Chemotherapy for Breast Cancer.

Biol Res Nurs 2019 Mar 31;21(2):142-156. Epub 2019 Jan 31.

1 School of Nursing, University of California, San Francisco, San Francisco, CA, USA.

Context:: Fatigue is the most common symptom associated with cancer and its treatment. Investigation of molecular mechanisms associated with fatigue may identify new therapeutic targets.

Objective:: The objective of this pilot study was to evaluate the relationships between gene expression and methylation status and evening fatigue severity in women with breast cancer who received chemotherapy. Read More

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http://dx.doi.org/10.1177/1099800418823286DOI Listing
March 2019
1 Read

Genetic Variants and the Cortisol Response in Children: An Exploratory Study.

Biol Res Nurs 2019 Mar 30;21(2):157-165. Epub 2019 Jan 30.

7 College of Nursing, The University of Iowa, Iowa, IA, USA.

Objective:: We examined genomic variation potentially associated with the cortisol stress response in children having a painful medical procedure.

Design:: Children 4-10 years old having a peripheral intravenous line inserted provided saliva samples for evaluation of the cortisol response as a biological measure of distress: two on the day of the procedure and two at home on a nonstressful day for comparison values. Children and biological parents also provided samples for genotyping of variants with known or suspected association with the cortisol stress response. Read More

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http://dx.doi.org/10.1177/1099800419826315DOI Listing
March 2019
3 Reads

Allostatic Load and Biomarkers of Stress in the Preterm Infant: An Integrative Review.

Biol Res Nurs 2019 Mar 17;21(2):210-223. Epub 2019 Jan 17.

1 School of Nursing, University of Connecticut, Storrs, CT, USA.

Background:: Every year, an estimated 15 million babies are born preterm (<37 weeks' gestational age) globally. These preterm infants are exposed to repeated stressful and often painful procedures as part of routine life-saving care within the neonatal intensive care unit (NICU). Low thresholds for tactile and nociceptive input make it more difficult for neonates to discriminate between noxious and nonnoxious stimuli, which can result in continuous activation of stress responses in an attempt to achieve stability through adaptation, or allostasis. Read More

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http://dx.doi.org/10.1177/1099800418824415DOI Listing
March 2019
2 Reads

Are Patients With Fibromyalgia in a Prothrombotic State?

Biol Res Nurs 2019 Mar 17;21(2):224-230. Epub 2019 Jan 17.

3 Department of Cell Biology, University of Granada, Granada, Spain.

Objectives:: The aim of this study was to investigate thrombosis-related parameters (blood coagulation parameters, platelet indices, red blood cell [RBC] count, and inflammatory markers) in patients with fibromyalgia (FM).

Method:: We carried out a case-control study with 35 women with FM and 12 age-matched healthy volunteers to analyze fibrinogen levels, prothrombin time, cephaline time, platelet count, platelet distribution width (PDW), mean platelet volume (MPV), RBC count, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio (PLR).

Results:: The results showed significantly increased fibrinogen levels ( p < . Read More

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http://dx.doi.org/10.1177/1099800418824716DOI Listing
March 2019
5 Reads

Glycemic Control in Insulin-Treated Patients With Type 2 Diabetes: Empowerment Perceptions and Diabetes Distress as Important Determinants.

Biol Res Nurs 2019 Mar 25;21(2):182-189. Epub 2018 Dec 25.

1 Department of Internal Medicine, Tri-Service General Hospital, Taipei, Taiwan.

The purpose of this cross-sectional study was to explore the determinants of hemoglobin A1c (HbA1c) levels in insulin-treated patients with Type 2 diabetes mellitus (T2DM) based on demographic and disease characteristics, self-reported regimen adherence factors (adherence in insulin regimen and self-monitoring of blood glucose), and psychosocial factors (decisional balance for insulin injection, health literacy, self-efficacy for insulin injection, diabetes distress, and empowerment perceptions). Via convenience sampling, 255 insulin-treated patients with T2DM were recruited from two endocrinology clinics in Taiwan. A self-report questionnaire was used to collect demographic and disease characteristics, regimen adherence factors, and psychosocial factors. Read More

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http://dx.doi.org/10.1177/1099800418820170DOI Listing
March 2019
2 Reads

Impact of Yoga on Inflammatory Biomarkers: A Systematic Review.

Biol Res Nurs 2019 Mar 20;21(2):198-209. Epub 2018 Dec 20.

4 Nursing Department, National Institutes of Health Clinical Center, Bethesda, MD, USA.

Background:: Many chronic conditions, including heart disease, cancer, and rheumatoid arthritis, are associated with underlying chronic inflammatory processes. Literature reviews have analyzed a variety of integrative therapies and their relationships with chronic inflammation. This systematic review is unique in reporting solely on yoga's relationship with inflammation. Read More

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http://dx.doi.org/10.1177/1099800418820162DOI Listing
March 2019
3 Reads

Associations Between Unhealthy Lifestyle Behaviors and Metabolic Syndrome by Gender in Young Adults.

Biol Res Nurs 2019 Mar 6;21(2):173-181. Epub 2018 Dec 6.

4 College of Management, Chaoyang University of Technology, Taichung City.

Objective:: Unhealthy lifestyle behaviors, such as smoking, drinking, betel-quid chewing, insufficient exercise, and inadequate sleep are significantly correlated with metabolic syndrome (MetS). To further understand this relationship, this study examined the main effect of unhealthy lifestyle behaviors and their interaction on MetS by gender in young adults.

Method:: A cross-sectional study involving 694 young adults from a national survey was performed in which demographic characteristics, unhealthy lifestyle behaviors, anthropometric measurements, and blood chemistry panels were collected during face-to-face interviews. Read More

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http://dx.doi.org/10.1177/1099800418816175DOI Listing
March 2019
1 Read
1.341 Impact Factor

Methicillin-Resistant Staphylococcus aureus and Other Multidrug-Resistant Colonizations/Infections in an Intensive Care Unit: Predictive Factors.

Biol Res Nurs 2019 Mar 11;21(2):190-197. Epub 2018 Dec 11.

2 Faculty of Nursing, Catholic University of Murcia (UCAM), Murcia, Spain.

Introduction And Objectives:: Methicillin-resistant Staphylococcus aureus (MRSA) is the most prevalent pathogen causing nosocomial infections in hospitals and health centers. This work is an effort to understand the epidemiology of MRSA and other multidrug-resistant pathogens in an intensive care unit (ICU) and to analyze characteristics that might determine the risk of MRSA colonization/infection in this unit.

Method:: An observational, 1-year prospective longitudinal study was conducted to obtain information about MRSA and other multidrug-resistant colonizations/infections. Read More

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http://dx.doi.org/10.1177/1099800418818387DOI Listing
March 2019
1 Read

Depressive Symptoms, Perceived Stress, and Cortisol in School-Age Children With Type 1 Diabetes: A Pilot Study.

Biol Res Nurs 2019 Mar 5;21(2):166-172. Epub 2018 Dec 5.

4 School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.

Despite adequate insulin regimens and concurrent treatments for Type 1 diabetes (T1D), many children have trouble achieving glycemic control, as evidenced by elevated HbA1c levels. Maternal and child depressive symptoms, as well as child perceived stress, are associated with less optimal glycemic control. Cortisol, a stress hormone, may mediate the relationships among depressive symptoms, perceived stress, and glycemic control. Read More

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http://journals.sagepub.com/doi/10.1177/1099800418813713
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http://dx.doi.org/10.1177/1099800418813713DOI Listing
March 2019
8 Reads

Melatonin Improves Mood Status and Quality of Life and Decreases Cortisol Levels in Fibromyalgia.

Biol Res Nurs 2018 Nov 11:1099800418811634. Epub 2018 Nov 11.

1 Department of Physiology, Neuroimmunophysiology and Chrononutrition Research Group, Faculty of Science, University of Extremadura, Badajoz, Spain.

Background:: Mood disturbances are implicated in the pathogenesis of fibromyalgia. The aim of this study was to assess the effect of different doses of melatonin on quality of life, mood status, pain, anxiety, and urinary cortisol levels in patients with fibromyalgia.

Methods:: After a 10-day baseline period for the collection of data about participants' initial status, participants took different doses of melatonin for 10 consecutive days each, with placebo given during the 10 days either before or between melatonin doses. Read More

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http://dx.doi.org/10.1177/1099800418811634DOI Listing
November 2018
23 Reads

Considerations When Designing a Microbiome Study: Implications for Nursing Science.

Biol Res Nurs 2019 Mar 8;21(2):125-141. Epub 2018 Nov 8.

3 Sensory Science and Metabolism Unit, Biobehavioral Branch, Division of Intramural Research, National Institute of Nursing Research, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.

Nurse scientists play an important role in studying complex relationships among human genetics, environmental factors, and the microbiome, all of which can contribute to human health and disease. Therefore, it is essential that they have the tools necessary to execute a successful microbiome research study. The purpose of this article is to highlight important methodological factors for nurse scientists to consider when designing a microbiome study. Read More

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http://dx.doi.org/10.1177/1099800418811639DOI Listing
March 2019
12 Reads

NuRsing Research in the 21st Century: R You Ready?

Biol Res Nurs 2018 Nov 1:1099800418810514. Epub 2018 Nov 1.

2 Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.

Nurse scientists are adept at translating findings from basic science into useful clinical- and community-based interventions to improve health. Over time, the focus of some nursing research has grown to include the assessment and evaluation of genomic and other output from high-throughput, or "omic," technologies as indicators related to health and disease. To date, the growth in the application of omics technologies in nursing research has included calls to increase attention to omics in nursing school curricula and educational training opportunities, such as the Summer Genetics Institute offered by the National Institute of Nursing Research. Read More

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http://dx.doi.org/10.1177/1099800418810514DOI Listing
November 2018
12 Reads

Beneficial Effects of Electroacupuncture on Neuropathic Pain Evoked by Spinal Cord Injury and Involvement of PI3K-mTOR Mechanisms.

Biol Res Nurs 2018 Oct 17:1099800418804896. Epub 2018 Oct 17.

1 Department of Pulmonary Medicine, The First Hospital of Jilin University, Changchun, Jilin, China.

The purpose of this study was to examine the beneficial effects of electroacupuncture (EA) on neuropathic pain evoked by spinal cord injury (SCI) and determine the underlying molecular mechanisms of these effects. SCI was induced in rats. Behavioral tests were performed to examine pain responses induced by mechanical and thermal stimulation. Read More

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http://dx.doi.org/10.1177/1099800418804896DOI Listing
October 2018
3 Reads

Association of Fatigue With TPH2 Genetic Polymorphisms in Women With Irritable Bowel Syndrome.

Biol Res Nurs 2018 Oct 11:1099800418806055. Epub 2018 Oct 11.

2 Department of Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, WA, USA.

Fatigue is the most common extraintestinal symptom in women with irritable bowel syndrome (IBS). Genetic polymorphisms of monoamines are associated with fatigue in many chronic diseases. In this pilot exploratory study, the primary aim was to determine whether genetic polymorphisms of tryptophan hydroxylase ( TPH1/TPH2), serotonin reuptake transporter ( SERT), or catechol-O-methyltransferase ( COMT) are associated with fatigue in women with IBS. Read More

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http://dx.doi.org/10.1177/1099800418806055DOI Listing
October 2018
8 Reads

Role of Exercise Activity in Alleviating Neuropathic Pain in Diabetes via Inhibition of the Pro-Inflammatory Signal Pathway.

Biol Res Nurs 2018 Oct 10:1099800418803175. Epub 2018 Oct 10.

5 Department of Thoracic Surgery, The First Hospital of Jilin University, Changchun, Jilin, China.

Hyperalgesia and allodynia are commonly observed in patients with diabetic neuropathy. The treatment and management of painful peripheral neuropathy is important in these patients. The purpose of this study was to examine the role of exercise in modulating neuropathic pain induced by diabetes. Read More

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http://journals.sagepub.com/doi/10.1177/1099800418803175
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http://dx.doi.org/10.1177/1099800418803175DOI Listing
October 2018
2 Reads

Diet Quality and High-Sensitivity C-Reactive Protein in Patients With Systemic Lupus Erythematosus.

Biol Res Nurs 2018 Oct 3:1099800418803176. Epub 2018 Oct 3.

1 Instituto de Investigación Biosanitaria (IBS), Granada, Spain.

Background And Aims: C-reactive protein (CRP) is commonly used as a biomarker for inflammation. Mild elevations of CRP have been seen in chronic autoimmune diseases like systemic lupus erythematosus (SLE), and CRP has been linked to an increased risk of cardiovascular events. Diet quality and certain dietary factors seem to influence CRP levels in healthy subjects. Read More

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http://dx.doi.org/10.1177/1099800418803176DOI Listing
October 2018
4 Reads

Effects of Listening to Live Singing in Patients Undergoing Hemodialysis: A Randomized Controlled Crossover Study.

Biol Res Nurs 2018 Sep 24:1099800418802638. Epub 2018 Sep 24.

6 Department of Medicine, Baylor College of Medicine, Selzman Institute for Kidney Health, Houston, TX, USA.

Background: Participation in music therapy is associated with improved psychological and physical indices among chronically ill patients. Listening to music during hemodialysis treatments positively affects patients' hemodynamics, laboratory values, quality of life, and physical symptoms. The effect of live singing during hemodialysis treatments, however, has not previously been studied. Read More

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http://dx.doi.org/10.1177/1099800418802638DOI Listing
September 2018
1 Read

A Systematic Review of Genetic Influence on Psychological Resilience.

Biol Res Nurs 2018 Sep 17:1099800418800396. Epub 2018 Sep 17.

2 College of Nursing, University of Nebraska Medical Center, Omaha, NE, USA.

When exposed to adversity, some individuals are at an increased risk of posttraumatic stress disorder, experiencing persistent biopsychosocial disturbances, whereas others adapt well, described as resilience. Resilience is a complex biopsychosocial phenomenon conceptualized as adaptation to adversity influenced by an individual's genetic variants, epistasis, epigenetics, and gene-by-environment interactions. Studies on psychological resilience have focused on behavioral and psychosocial variables with far less examination of the genetic contributions. Read More

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http://dx.doi.org/10.1177/1099800418800396DOI Listing
September 2018
4 Reads

Exploratory Study of Associations Between DNA Repair and Oxidative Stress Gene Polymorphisms and Cognitive Problems Reported by Postmenopausal Women With and Without Breast Cancer.

Biol Res Nurs 2018 Sep 13:1099800418799964. Epub 2018 Sep 13.

2 School of Nursing, University of Pittsburgh, Pittsburgh, USA.

Purpose: Women with breast cancer report varying frequencies of cognitive problems during adjuvant systemic therapy. This variability suggests latent subgroups. Therefore, we identified latent subgroups of self-reported cognitive problems among postmenopausal women with and without breast cancer. Read More

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http://dx.doi.org/10.1177/1099800418799964DOI Listing
September 2018
2 Reads

Biological Processes and Biomarkers Related to Frailty in Older Adults: A State-of-the-Science Literature Review.

Biol Res Nurs 2019 Jan 9;21(1):80-106. Epub 2018 Sep 9.

3 School of Nursing, University of Minnesota, Minneapolis, MN, USA.

The objectives of this literature review were to (1) synthesize biological processes linked to frailty and their corresponding biomarkers and (2) identify potential associations among these processes and biomarkers. In September 2016, PubMed, Cumulative Index to Nursing and Allied Health, Cochrane Library, and Embase were searched. Studies examining biological processes related to frailty in older adults (≥60 years) were included. Read More

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http://dx.doi.org/10.1177/1099800418798047DOI Listing
January 2019
3 Reads

A Large Randomized Trial: Effects of Mindfulness-Based Stress Reduction (MBSR) for Breast Cancer (BC) Survivors on Salivary Cortisol and IL-6.

Biol Res Nurs 2018 Aug 5:1099800418789777. Epub 2018 Aug 5.

2 H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

Breast cancer survivors (BCS) often experience psychological and physiological symptoms after cancer treatment. Mindfulness-based stress reduction (MBSR), a complementary and alternative therapy, has reduced subjective measures of stress, anxiety, and fatigue among BCS. Little is known, however, about how MBSR affects objective markers of stress, specifically the stress hormone cortisol and the pro-inflammatory cytokine interleukin-6 (IL-6). Read More

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http://dx.doi.org/10.1177/1099800418789777DOI Listing
August 2018
8 Reads

Sleep, Lifestyle Behaviors, and Cardiometabolic Health Markers in Overweight/Obese Young Adults: A Pilot Study Using the SenseWear® Armband.

Biol Res Nurs 2018 10 2;20(5):541-548. Epub 2018 Aug 2.

2 Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.

Aim: This pilot study examined associations between sleep quality and metabolic risk profiles, underlying hormones, inflammatory markers, and behaviors in overweight and obese young adults, aged 18-29 years.

Design: Cross-sectional, descriptive, correlational study design.

Method: A partial sample ( n = 29) was re-recruited from a parent study on screening for risk of early-onset diabetes. Read More

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http://dx.doi.org/10.1177/1099800418791047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346317PMC
October 2018
3 Reads
1 Citation
1.341 Impact Factor

Oxidative Stress and Preterm Birth: An Integrative Review.

Biol Res Nurs 2018 10 1;20(5):497-512. Epub 2018 Aug 1.

3 College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA.

Background: A variety of methods and measures have been used to quantify oxidative stress in clinical studies related to preterm birth (PTB), and studies have reported conflicting findings. No integrative reviews have been conducted.

Objective: To describe specific molecules used as markers of oxidative stress and methods to measure these molecules and to review the literature for associations between oxidative stress and PTB specific to these molecules. Read More

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http://dx.doi.org/10.1177/1099800418791028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346316PMC
October 2018
10 Reads

Associations of Anthropometric Characteristics, Dietary Habits, and Aerobic Capacity With Cardiovascular Risk Factors of Health-Science Students.

Biol Res Nurs 2018 10 19;20(5):549-557. Epub 2018 Jul 19.

1 Department of Nursing I, Faculty of Medicine and Nursing, University of the Basque Country, Bizkaia, Spain.

The aim of this cross-sectional study was to study the relative importance of dietary habits and aerobic capacity in parameters related to cardiovascular risk in 271 female and 95 male health-science students (mean age = 19.1 ± 1.4 years). Read More

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http://dx.doi.org/10.1177/1099800418788652DOI Listing
October 2018
4 Reads

Catecholamine and Indolamine Pathway: A Case-Control Study in Fibromyalgia.

Biol Res Nurs 2018 10 15;20(5):577-586. Epub 2018 Jul 15.

2 Department of Health Sciences, University of Jaén, Jaén, Spain.

Objectives: Fibromyalgia (FM) is a complex syndrome characterized by widespread pain. Its etiology is unclear, and diagnosis is difficult. The aim of this study was to assess plasma levels of monoamine neurotransmitters (catecholamines, indolamines, and intermediate metabolites) in patients with FM and healthy controls to investigate possible alterations in the metabolism of these molecules in FM. Read More

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http://dx.doi.org/10.1177/1099800418787672DOI Listing
October 2018
16 Reads

The Effect of the Relationship of APOE Polymorphisms and Cerebral Vasospasm on Functional Outcomes in Children With Traumatic Brain Injury.

Biol Res Nurs 2018 10 11;20(5):566-576. Epub 2018 Jul 11.

3 Department of Neurology, Duke University School of Medicine, Durham, NC, USA.

Background: Pediatric traumatic brain injury (TBI) is a leading cause of death and disability. Polymorphisms in the apolipoprotein E ( APOE) gene have been linked to cerebral vasospasm (CV) and poor outcomes in adults with TBI, yet these associations remain poorly defined in children.

Objective: We examined the effect of the relationship between APOE polymorphisms and CV on functional outcomes in children with a TBI. Read More

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http://dx.doi.org/10.1177/1099800418785982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346318PMC
October 2018
4 Reads

Potential Role of the Gut Microbiome in ALS: A Systematic Review.

Biol Res Nurs 2018 10 20;20(5):513-521. Epub 2018 Jun 20.

1 Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.

Amyotrophic lateral sclerosis (ALS) etiology and pathophysiology are not well understood. Recent data suggest that dysbiosis of gut microbiota may contribute to ALS etiology and progression. This review aims to explore evidence of associations between gut microbiota and ALS etiology and pathophysiology. Read More

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http://dx.doi.org/10.1177/1099800418784202DOI Listing
October 2018
8 Reads

Dose of Early Therapeutic Mobility: Does Frequency or Intensity Matter?

Biol Res Nurs 2018 10 14;20(5):522-530. Epub 2018 Jun 14.

8 Department of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

Objective: Investigate the feasibility of a nurse-led mobility protocol and compare the effects of once- versus twice-daily episodes of early therapeutic mobility (ETM) and low- versus moderate-intensity ETM on serum biomarkers of inflammation and selected outcomes in critically ill adults.

Design: Randomized interventional study with repeated measures and blinded assessment of outcomes.

Setting: Four adult intensive care units (ICUs) in two academic medical centers. Read More

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http://dx.doi.org/10.1177/1099800418780492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346319PMC
October 2018
21 Reads

Associations Between Secondhand Tobacco Smoke Exposure and Nicotine Dependence and Smoking Cessation Attempts Among Adult Tobacco Users With a Psychiatric Disorder.

Biol Res Nurs 2018 10 14;20(5):558-565. Epub 2018 Jun 14.

1 University of Kentucky College of Nursing, Lexington, KY, USA.

Introduction: Secondhand smoke exposure (SHSe) is predictive of greater nicotine dependence (ND) and poor smoking cessation (SC) outcomes. SHSe and its impact on ND and SC attempts in people with psychiatric disorders (PD) remain poorly understood. Hence, the objectives of this study were to (1) quantify SHSe, (2) examine the association of SHSe with ND, and (3) assess the association between SHSe and SC among tobacco users with PD. Read More

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http://dx.doi.org/10.1177/1099800418781914DOI Listing
October 2018
5 Reads

Chronic Stress in Children and Adolescents: A Review of Biomarkers for Use in Pediatric Research.

Authors:
Eileen M Condon

Biol Res Nurs 2018 10 4;20(5):473-496. Epub 2018 Jun 4.

1 Yale School of Nursing, West Campus Drive, Orange, CT, USA.

Problem: Incorporating biomarkers of chronic stress into pediatric research studies may help to explicate the links between exposure to adversity and lifelong health, but there are currently very few parameters to guide nurse researchers in choosing appropriate biomarkers of chronic stress for use in research with children and adolescents.

Methods: Biomarkers of chronic stress are described, including primary mediators (glucocorticoids, catecholamines, and cytokines) and secondary outcomes (neurologic, immune, metabolic, cardiovascular, respiratory, and anthropometric) of the chronic stress response.

Results: Evidence of the use of each biomarker in pediatric research studies is reviewed. Read More

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http://dx.doi.org/10.1177/1099800418779214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346321PMC
October 2018
3 Reads

Eating Behavior, Stress, and Adiposity: Discordance Between Perception and Physiology.

Biol Res Nurs 2018 10 31;20(5):531-540. Epub 2018 May 31.

2 Digestive Disorders Unit, Division of Intramural Research, Department of Health and Human Services (DHHS), National Institute of Nursing Research (NINR), National Institutes of Health (NIH), Bethesda, MD, USA.

The purpose of the study was to examine the interrelationships among stress, eating behavior, and adiposity in a cohort of normal- and overweight individuals. Clinical markers of physiological stress (fasting serum cortisol) and adiposity (body mass index [BMI] and percent body fat) were obtained from participants selected for a natural history protocol ( n = 107). Self-reported data on eating behavior (using the Three-Factor Eating Questionnaire subscales such as Cognitive Restraint, Disinhibition, and Hunger) and psychological stress (via the Perceived Stress Scale) were evaluated. Read More

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http://dx.doi.org/10.1177/1099800418779460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346320PMC
October 2018
5 Reads

Biological Sex Differences in Depression: A Systematic Review.

Biol Res Nurs 2018 07 14;20(4):383-392. Epub 2018 May 14.

1 Department of Basic Psychological Processes and their Development, University of the Basque Country, San Sebastián, Spain.

Depression is the leading cause of disability worldwide, and its prevalence is 2 times higher in women than in men. There is, however, a lack of data on sex-specific pathophysiology of this disorder. The purpose of this systematic review is to identify the biological sex differences found in major depressive disorder (MDD) in studies published in the last 10 years. Read More

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http://dx.doi.org/10.1177/1099800418776082DOI Listing
July 2018
6 Reads

Impact of Positive Pressure Treatment of the Airway on Health-Related Quality of Life in Elderly Patients With Obstructive Sleep Apnea.

Biol Res Nurs 2018 07 3;20(4):452-461. Epub 2018 May 3.

1 Sleep Unit, Respiratory Department, University Hospital Reina Sofia, Córdoba, Spain.

Background: Obstructive sleep apnea (OSA) is a chronic illness that increases in prevalence with age. Treatment includes continuous positive airway pressure (CPAP) devices. Studies about the use of CPAP in the elderly are scarce. Read More

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http://dx.doi.org/10.1177/1099800418774633DOI Listing
July 2018
9 Reads

Influence of Nitrosative Stress on Fatigue During Childhood Leukemia Treatment.

Biol Res Nurs 2018 07 1;20(4):403-409. Epub 2018 May 1.

1 School of Nursing, Duke University, Durham, NC, USA.

The focus on a cure for childhood leukemia over the last three decades has resulted in survival rates of more than 80%. However, efforts to manage leukemia-treatment symptoms have not kept pace with new therapies. Symptom toxicity during treatment can result in complications, treatment delays, and therapy dose reductions. Read More

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http://dx.doi.org/10.1177/1099800418772907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346315PMC
July 2018
8 Reads
1.341 Impact Factor

Mortality in Advanced Chronic Obstructive Pulmonary Disease and Heart Failure Following Cardiopulmonary Rehabilitation.

Biol Res Nurs 2018 07 29;20(4):429-439. Epub 2018 Apr 29.

2 Health Services Research and Development, VA Puget Sound Health Care System, Seattle, WA, USA.

Cardiopulmonary rehabilitation (CR) improves physical function and quality of life (QoL) in chronic obstructive pulmonary disease (COPD) and heart failure (HF), but it is unknown if CR improves outcomes in very severe disease. This study's purpose was to describe functional capacity (6-min walk distance [6MWD], steps/day), symptoms (dyspnea, depression), QoL (Short-Form Health Survey-Veterans [SF-36 V]) and cardiopulmonary function ( N-terminal pro-brain natriuretic peptide [NT-proBNP], forced expiratory volume in 1 s [FEV]), and derive predictors of mortality among patients with severe COPD and HF who participated in CR.

Methods And Results: In this secondary analysis of a randomized controlled trial comparing two CR methods in severe COPD and HF, 90 (COPD = 63, HF = 27) male veterans, mean age 66 ± 9. Read More

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http://dx.doi.org/10.1177/1099800418772346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346312PMC
July 2018
4 Reads

Mechanisms and Measurement of Changes in Gene Expression.

Biol Res Nurs 2018 07 29;20(4):369-382. Epub 2018 Apr 29.

1 Department of Physiological Nursing, School of Nursing, University of California, San Francisco, CA, USA.

Research on gene expression (GE) provides insights into the physiology of a cell or group of cells at a given point in time. Studies of changes in GE can be used to identify patients at higher risk for various medical conditions, a higher symptom burden, and/or the adverse consequences associated with various treatments. The aims of this article are as follows: (1) to describe the different types of RNA transcripts, (2) to describe the processes involved in GE (i. Read More

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http://dx.doi.org/10.1177/1099800418772161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346310PMC
July 2018
4 Reads

Primer in Genetics and Genomics Series: Final Remarks.

Biol Res Nurs 2018 05;20(3):253-254

1 International Society of Nurses in Genetics (ISONG), Pittsburgh, PA, USA.

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http://dx.doi.org/10.1177/1099800418766616DOI Listing
May 2018
4 Reads

Negative Correlation of Serum Adiponectin Levels With Carotid-Femoral Pulse Wave Velocity in Patients Treated With Hemodialysis.

Biol Res Nurs 2018 07 10;20(4):462-468. Epub 2018 Apr 10.

1 Division of Nephrology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.

Purpose: The aim of this study was to evaluate the relationship between serum adiponectin levels and carotid-femoral pulse wave velocity (cfPWV) in hemodialysis (HD) patients.

Method: Blood samples were obtained from 120 HD patients. cfPWV was measured with a validated tonometry system (SphygmoCor; AtCor Medical, West Ryde, Australia). Read More

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http://dx.doi.org/10.1177/1099800418768887DOI Listing
July 2018
6 Reads

Integrative Review of the Relationship Between Sleep Disturbances and Episodic Memory in Older Adults.

Biol Res Nurs 2018 07 4;20(4):440-451. Epub 2018 Apr 4.

1 College of Nursing, The University of Nebraska Medical Center, Omaha, NE, USA.

Impaired episodic memory in older adults has been linked to many factors. One of these factors is sleep disturbances, which are reported by more than 50% of older adults. The relationship between episodic memory and sleep disturbances remains unclear, however, because of the multiple types of measures of sleep and episodic memory used in previous studies. Read More

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http://dx.doi.org/10.1177/1099800418768070DOI Listing
July 2018
8 Reads

Relationships Between Glycemic Control and Cardiovascular Fitness.

Biol Res Nurs 2018 07 2;20(4):422-428. Epub 2018 Apr 2.

4 Department of Health Systems Science, College of Nursing, University of Illinois at Chicago, Chicago, IL, USA.

Introduction: Diabetes is a serious health problem affecting approximately 29.1 million individuals in the United States. Another 86 million have prediabetes. Read More

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http://dx.doi.org/10.1177/1099800418767572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346313PMC
July 2018
4 Reads

A Systematic Review of Biological Mechanisms of Fatigue in Chronic Illness.

Biol Res Nurs 2018 07 14;20(4):410-421. Epub 2018 Mar 14.

1 School of Nursing, University of Pennsylvania, Philadelphia, PA, USA.

Fatigue, a commonly reported symptom, is defined as an overwhelming, debilitating, and sustained sense of exhaustion that decreases the ability to function and carry out daily activities. To date, cancer researchers have been in the forefront in investigating the possible biological mechanisms of fatigue, identifying inflammation, dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, and activation of the autonomic nervous system. The purpose of this systematic review is to describe fatigue and what is known about the biological mechanisms described in cancer in five chronic, noninfectious illnesses: heart failure, multiple sclerosis, chronic kidney disease, rheumatoid arthritis, and chronic obstructive pulmonary disease. Read More

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http://dx.doi.org/10.1177/1099800418764326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346311PMC
July 2018
8 Reads

Changes in Oxidant Defense, Apoptosis, and Cognitive Abilities During Treatment for Childhood Leukemia.

Biol Res Nurs 2018 07 7;20(4):393-402. Epub 2018 Mar 7.

4 Duke University School of Nursing, Durham, NC, USA.

Aggressive central nervous system (CNS)-directed treatment for acute lymphoblastic leukemia (ALL), the most prevalent cancer among children and adolescents, prevents metastasis of leukemia cells into the brain. Up to 60% of survivors experience cognitive problems, but knowledge about risk factors for and mechanisms of neurologic injury is lacking. Objectives of the present study were to (1) quantify changes in oxidant defense and apoptosis over the course of ALL therapy and (2) elucidate risk factors for long-term cognitive problems. Read More

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http://dx.doi.org/10.1177/1099800418763124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346314PMC
July 2018
8 Reads

Altered DNA Methylation Patterns Associated With Clinically Relevant Increases in PTSD Symptoms and PTSD Symptom Profiles in Military Personnel.

Biol Res Nurs 2018 05 7;20(3):352-358. Epub 2018 Mar 7.

1 National Institute of Nursing Research (NINR), National Institutes of Health, Bethesda, MD, USA.

Military personnel experience posttraumatic stress disorder (PTSD), which is associated with differential DNA methylation across the whole genome. However, the relationship between these DNA methylation patterns and clinically relevant increases in PTSD severity is not yet clearly understood. The purpose of this study was to identify differences in DNA methylation associated with PTSD symptoms and investigate DNA methylation changes related to increases in the severity of PTSD in military personnel. Read More

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http://dx.doi.org/10.1177/1099800418758951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993080PMC
May 2018
8 Reads

Primer in Genetics and Genomics, Article 7-Multifactorial Concepts: Gene-Gene Interactions.

Biol Res Nurs 2018 05 7;20(3):359-364. Epub 2018 Mar 7.

2 Department of Genetics, Genomics, and Informatics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.

Most common disorders affecting human health are not attributable to simple Mendelian (single-gene) inheritance patterns. Rather, the risk of developing a complex disease is often the result of interactions across genes, whereby one gene modifies the phenotype of another gene. These types of interactions can occur between two or more genes and are referred to as epistasis. Read More

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http://dx.doi.org/10.1177/1099800418761098DOI Listing
May 2018
4 Reads

Comparison of Hair Cortisol Levels and Perceived Stress in Mothers Who Deliver at Preterm and Term.

Biol Res Nurs 2018 05 28;20(3):292-299. Epub 2018 Feb 28.

1 University of South Florida College of Nursing, Tampa, FL, USA.

Objective: To evaluate relationships between hair cortisol levels and perceived stress in mothers who deliver preterm and term. We hypothesized that the rate of change in cortisol levels would be greater in the preterm delivery group.

Methods: This preliminary study compared hair cortisol levels and Perceived Stress Scale (PSS) scores in predominately Caucasian mothers who delivered preterm ( n = 22) and term ( n = 30). Read More

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http://dx.doi.org/10.1177/1099800418758952DOI Listing
May 2018
4 Reads

A Systematic Review of Placental Biomarkers Predicting Small-for-Gestational-Age Neonates.

Biol Res Nurs 2018 05 28;20(3):272-283. Epub 2018 Feb 28.

2 Department of Women, Children & Family Health Science, College of Nursing, University of Illinois at Chicago, Chicago, IL, USA.

Background: Neonates born small for gestational age (SGA) face increased risk of neonatal mortality, childhood developmental problems, and adult disease. The placenta is a key factor in SGA development because of its multiple biological processes that underlie fetal growth. However, valid and reliable placental biomarkers of SGA have not been determined. Read More

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http://dx.doi.org/10.1177/1099800418760997DOI Listing
May 2018
5 Reads

Different Sickness Responses in Adult and Aged Rats Following Lipopolysaccharide Administration.

Biol Res Nurs 2018 05 25;20(3):335-342. Epub 2018 Feb 25.

3 School of Nursing, Adult Health Nursing, The University of North Carolina at Greensboro, Greensboro, NC, USA.

Objective: Immune challenges result in sickness responses such as decreased activity, fever, and spatial learning deficits. While these responses occur simultaneously, they are not usually evaluated concurrently or for an extended time. The purpose of this study was to examine how an immune challenge affected activity and temperature responses in animals tested concurrently in the Morris water maze (MWM) over 5 days and how aging interacts with such responses. Read More

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http://dx.doi.org/10.1177/1099800418759599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993078PMC
May 2018
4 Reads